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Books in Molecular biology cellular biology and genetics

This collection offers insights into gene expression, cell signalling, and genetic regulation. Supporting researchers, clinicians, and students, it features advanced techniques, genetic engineering, and disease mechanisms, fostering innovations in personalized medicine, regenerative therapies, and molecular diagnostics.

  • Cell Death Part C

    • 1st Edition
    • Volume 208
    • English
    Cell Death: Part C, Volume 208 continues the comprehensive exploration of cellular mechanisms governing the fate of cells in health and disease. This volume delves deep into the molecular pathways, regulatory networks, and biological consequences of various cell death modalities, including apoptosis, necrosis, autophagy, ferroptosis, pyroptosis, and other emerging forms.

  • Molecular Targets and Therapeutic Design

    • 1st Edition
    • Volume 152
    • English
    Molecular Targets and Therapeutic Design, Volume 152 provides a comprehensive overview of the current landscape and future directions in the identification and exploitation of molecular targets for the development of new therapeutics. This volume brings together leading experts to discuss the fundamental principles of target discovery, validation, and the strategies used to design molecules that modulate biological pathways in disease. Topics covered in this new release include Recent Strategies and Approaches for the Development of Molecularly Targeted Nanomedicine, Transcriptomic Profiling for Therapeutic Target Discovery in Neuropsychiatric Conditions, Transcriptomic Insights into Hormone-Driven Malignancies: Toward Targeted Therapeutic Strategies, and much more.Additional chapters cover Targeting Kinases in Neurodegenerative Diseases and Cancer: Structural Insights and Therapeutic Strategies, Small molecular therapeutic targets for neurodegenerative diseases, Signaling cascades of Tau protein, Understanding molecular role of lipids for Alzheimer's disease, Clinical Challenges and Therapeutic Strategies in Chordoma, Molecular Characterization and Experimental Models of Chordoma, Disordered Proteins as Fuzzy Viral Drug Targets, amongst other timely topics.

  • Statistical Bioinformatics with R

    • 2nd Edition
    • Sunil K. Mathur
    • English
    Statistical Bioinformatics with R, Second Edition offers a balanced treatment of statistical theory within the context of bioinformatics applications. The book goes beyond gene expression and sequence analysis to include a careful integration of statistical theory in bioinformatics. The inclusion of R codes, along with the development of advanced methodologies such as Bayesian and Markov models, equips students with a solid foundation for conducting bioinformatics research. Sections incorporate the latest advancements in bioinformatics and statistical methodologies, including new chapters on cutting-edge topics such as high-throughput sequencing data analysis, AI/machine learning applications in bioinformatics, and advanced statistical methods.From new and updated practical examples and case studies that illustrate real-world applications of statistical techniques to bioinformatic problems, to enhanced end-of-chapter exercises, detailed code annotations, and an improved companion website with supplementary materials, including datasets and R scripts, this book is a valuable resource for both self-study and formal coursework, fostering a deeper understanding of statistical bioinformatics and equipping readers with the skills needed to tackle complex biological data analysis challenges.

  • The Potential of Extracellular Vesicles from Plant and Animal Sources for Improving Human Beauty and Health

    • 1st Edition
    • Khalid Rehman Hakeem + 2 more
    • English
    The Potential of Extracellular Vesicles from Plant and Animal Sources for Improving Human Beauty and Health is a comprehensive resource that consolidates the latest research on the mechanisms of extracellular vesicles (EVs) and their applications in the cosmetic industry. The book explores a range of topics, including the latest techniques in isolation and characterization of EVs, safety considerations, methods, and challenges associated with large-scale production, and recent advancements in biomedical applications. The therapeutic potential of EVs for age-related neurological conditions and autoimmune skin diseases is investigated, as well as the application of EVs for skincare, hair loss and anti-aging products.The book considers EVs from a variety of sources, including humans, plants, animals and bacteria, highlighting their major differences. It also includes a discussion of market trends and the global impact for EV products in cosmetic and anti-aging industries. With growing interest in the role of extracellular vesicles in enhancing health and beauty, this book provides invaluable insights to researchers working in this field, equipping them with the knowledge to leverage EVs for innovative cosmetic applications and natural solutions.

  • Molecular Insights into Proteinopathies

    Increased Scope from Neurodegeneration to other Pathologies of the Brain
    • 1st Edition
    • Eva Žerovnik + 1 more
    • English
    Molecular Insights into Proteinopathies: Increased Scope from Neurodegeneration to other Pathologies of the Brain investigates the molecular events that lead to various diseases. The book is divided into four parts, the first of which delves into protein aggregation across a range of diseases, including Alzheimer’s disease, Parkinson’s disease, schizophrenia, and neuropsychiatric diseases. It then moves on to discuss signaling pathways and biomarkers of disease, including oxidative stress, mitochondrial decline, and dysregulated molecular pathways. The third part explores small molecules as modulators of key processes in the pathogenesis of proteinopathies, including antioxidants, polyphenol compounds, metal chelators, and repurposed drugs that modulate proteinopathies.The final section considers biophysical methods, molecular dynamics, and machine learning approaches in the study of these aspects. The book provides a detailed overview of protein dysfunction and its implications for health and disease, aiding understanding of protein condensates and aggregates, protein misfolding, co-chaperoning and toxicity of pre-amyloid aggregates. By understanding the fundamental properties underlying these, the book paves the way for investigating how proteinopathies could be treated.

  • Advances in Biomedical Engineering - Part A

    • 1st Edition
    • Volume 402
    • English
    Advances in Biomedical Engineering, Part A, Volume 402 provides a comprehensive overview of the latest developments, innovations, and research in the rapidly evolving field of biomedical engineering. This book covers a broad spectrum of topics, including medical imaging, biomaterials, tissue engineering, biomechanics, bioinstrumentation, and healthcare technologies. Specific chapters include Advances in biomedical engineering, Recent advances in nanomedicine as drug delivery systems, Advances in Nano biomaterials for Biomedical Engineering, Neurodiagnostic: Advances in diagnostic tools, Advances in Ferroptosis Research and Application, Bioink-based 3D Bioprinting: Paving the Path for Regenerative Medicine, and MRI Acute/Sub-Acute Ischemic Stroke Segmentation with Deep Learning: A Comprehensive Review.

  • Transposable Elements in Health and Disease

    • 1st Edition
    • Volume 116
    • English
    Transposable Elements in Health and Disease, Volume 116 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting comprehensive chapters on a variety of timely topics. Specific chapters examine Transposable Elements in Human Cancer: Regulation, Activation, and Genomic Consequences, Retrotransposons as both “architects” and “saboteurs” in the nervous system, Shaping Mammalian Genomes: The Regulation and Co-option of Transposable Elements, Transposable element analysis in -omics data, and Transposable elements in Aging: from biomarkers to effectors.Together, these contributions provide valuable insights into the mechanisms and impacts of transposable element activity, advancing our understanding of their broad significance in genetics, development, health, and disease.

  • Mucins

    • 1st Edition
    • Volume 732
    • English
    Mucins, Volume 732 serves as a valuable resource for researchers aiming to investigate mucin biology in greater depth, offering a wide range of experimental approaches and analytical strategies. Topics in this new release cover Enrichment/isolation... glycoproteomics, Mucinase cleavage characterization and usage in glycoproteomics, Fluorescent protein-based FRET substrates for activity screening of mucinases, Development of clinical lectin assays based on MS glycomic discovery, Enzymatic selective sulfation of synthetic mucins, cryoEM, Cell-based mucin arrays and glycoengineering, CRISPR screens to characterize and identify glycan-binding proteins, and much more.Additional sections cover MD Simulations, Interactions with pathogenic bacteria, Interactions with microbiota, Covalent crosslinking of mucins, Liquid Glycan and Liquid Lectin Array-based exploration of musin recognition, Quantification of mucins, Mucins in IBD, Investigations of mucins and innate immunity, Generating synthetic mucin glycopeptides, and Microscopy and imaging.

  • Glycobiology

    • 1st Edition
    • Volume 153
    • English
    Glycobiology provides a comprehensive overview of glycobiology, exploring the structure, function, and biology of carbohydrates and glycoconjugates in living organisms. Covering key topics such as glycan biosynthesis, glycoproteins, glycolipids, and the role of glycans in health and disease, the book serves as an essential resource for researchers, students, and professionals interested in the rapidly advancing field of glycobiology.

  • Ion Channels in Cellular Pathophysiology Part A

    • 1st Edition
    • Volume 97
    • English
    Ion Channels in Cellular Pathophysiology, Part A, Volume 97 in the Current Topics in Membranes series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Possible therapeutic effects of essential oils on Na channels in experimental diabetic neuropathy, Modulation of ion channels by Group I metabotropic glutamate receptors, ATP-sensitive potassium channels in neurons: roles in and beyond metabolic control, Chemically induced cardiotoxicity: role of voltage dependent ion channels, Thyroid Hormone Deficiency-Induced Cardiac Ion Channel Dysfunction: Molecular Mechanisms and Arrhythmic Implications, and much more.Additional chapters discuss Pathophysiological Insights into Ion Channel Dysregulation and Electrical Remodeling in Cardiac Cells During Trypanosoma cruzi Infection, Targeting Sodium Channels in Neuroblastoma: Implications for Cellular Physiology, Breast cancer and voltage ion channels, Alpha-helical charged peptides a new concept of NaV gating modifiers, Nerve electrophysiological alterations in experimental diabetic neuropathy, and Cardioprotective effect of natural products on doxorubicin-induced acute cardiotoxicity and cardiac ischemia-reperfusion injury.

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