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Books in Molecular biology cellular biology and genetics

This collection offers insights into gene expression, cell signalling, and genetic regulation. Supporting researchers, clinicians, and students, it features advanced techniques, genetic engineering, and disease mechanisms, fostering innovations in personalized medicine, regenerative therapies, and molecular diagnostics.

  • PACAP

    From Discovery to Function
    • 1st Edition
    • David Vaudry + 1 more
    • English
    PACAP: From Discovery to Function in Health and Disease serves as a comprehensive review covering all aspects of PACAP and its receptors, from expression to function in healthy tissues and disease models. The book introduces the biochemical, pharmacological and signaling properties of PACAP before exploring the biological actions of PACAP in normal health and pathological conditions. It considers PACAP in relation to various aspects, including pain, stress, brain injury, tumor cells and neurodegenerative disease. Effect on peripheral organs is also covered, from the gastrointestinal tract and cardiovascular system to immune cells and bones, among others. Therapeutic potential is also explored. This is a volume in the Molecular Mediators in Health and Disease book series, and provides a complete analysis of PACAP and the latest research in the field. Thus it is an ideal guide for researchers interested in PACAP and its impact across health and disease.

  • Mitochondrial Intoxication

    • 2nd Edition
    • Marcos Roberto de Oliveira
    • English
    Mitochondrial Intoxication, Second Edition offers a comprehensive and fully updated exploration of the impact of toxic molecules on mitochondrial physiology, and the diseases that result from their dysfunction. Divided into three sections, the book opens with a detailed overview of mitochondrial physiology, molecular markers of mitochondrial intoxication and challenges of mitochondrial profiling during pre-clinical studies. It then focuses on endogenous toxicants and their impact on mitochondria, including new chapters on lipids, glucose and microbiota-derived toxicants. Amyloid-β peptide and its impact on mitochondrial dysfunction is also a new addition to this book, as well as inflammation-induced mitochondrial intoxication. The final section explores exogenous toxicants, such as pollutants, food additives, illicit and pharmaceutical drugs, pesticides and heavy metals. The effects of micro- and nanoplastics on mitochondrial function are newly covered. Furthermore, the latest computational tools in mitochondrial toxicity research are investigated. Incorporating the latest advances in the field, “Mitochondrial Intoxication, Second Edition” offers cutting-edge insights on mitochondrial toxicity, and serves as an invaluable resource for researchers and advanced students in cell biology, molecular biology, toxicology, biochemistry, pharmacology, and related fields.

  • Microbial Technologies for Sustainable Waste Management

    • 1st Edition
    • Rajneesh Kumar + 2 more
    • English
    Microbial Technologies for Sustainable Waste Management explores advanced waste management through microbial processes. It investigates the current limitations of traditional waste treatment and the potential for microbial cell factories in bringing innovative solutions to this field. Beginning with an introduction to the role of microbes in waste management, the book examines global case studies demonstrating success stories in microbial waste treatment and microbial innovations for biotechnological applications in waste conversion. The book includes chapters focused on microbial pathways for anaerobic digestion, hydrolysis, and fermentation, and microbial technologies for industrial applications such as wastewater treatment and the biofuel industry. Additionally it considers microbial remediation of hazardous and toxic waste, microbial fuel cells, and strategies for plastic waste degradation. Emerging technologies, such as AI integration, microbial nanotechnology, and engineered microbes, are discussed, along with their environmental impacts and potential for scaling up to commercial applications. Microbial Technologies for Sustainable Waste Management is an invaluable resource for students, researchers, and academicians involved in the study of microbial cell factories and their applications, including professionals across microbiology, biotechnology, cell biology, environmental science and bioengineering.

  • Histone Deacetylases in Neurodegenerative Disease Part A

    • 1st Edition
    • Volume 733
    • English
    Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Cell Death Part D

    • 1st Edition
    • Volume 209
    • English
    Cell Death Part D explores the latest advances in the mechanisms, regulation, and significance of cell death in health and disease. Covering diverse topics such as apoptosis, necrosis, autophagy, and emerging pathways, this volume presents current research and novel insights from leading experts. It serves as a valuable resource for researchers, clinicians, and students interested in understanding cellular processes and their implications for therapy and diagnostics.

  • Viruses as Therapeutic Agents for Cancer

    • 1st Edition
    • Volume 171
    • English
    Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Biology

    A Human Health Perspective
    • 1st Edition
    • Harry E. Peery + 2 more
    • English
    Biology: A Human Health Perspective is a valuable clinically oriented textbook for those going into the health professions. It offers important medical case histories and complex colour illustrations, interacts with the reader and asks questions throughout. Units cover the basic chemistry of biology and cell origins, and energy and protein processing, before discussing cell reproduction, genetics, and evolution, and their place in public healthcare. Clinical applications and medical terminology are also included across the chapters, and pioneering medical developments such as holographic surgery, robotic neurosurgery and tractography are featured. This textbook, along with supporting ancillary materials such as PowerPoint slides, solution manuals and quiz banks, is a vital resource for all undergraduate students studying biology or for those looking to develop a career in a health profession who need a basic understanding of the field.

  • Protein Misfolding and Human Diseases

    Deciphering the Central Role of Pathological Aggregation
    • 1st Edition
    • Pranav Kumar Prabhakar + 2 more
    • English
    Protein Misfolding and Human Diseases: Deciphering the Central Role of Pathological Aggregation investigates the misfolding of proteins and implications for a variety of debilitating conditions. The book provides a comprehensive overview of pathological protein aggregation, exploring its mechanisms in the context of specific illnesses, including Alzheimer's disease, Parkinson’s disease, Huntington’s disease, prion diseases, ALS and systemic amyloidosis. It addresses disrupted cellular pathways and failures in protein homeostasis during aging, delineating the unifying principles across protein conformational disorders. It also features structural insights into protein aggregates from amyloid fibrils to inclusion bodies, and offers therapeutic strategies to disrupt aggregation pathways, enhance cellular protein quality control, and provide immunotherapy solutions. Finally, the book closes with a discussion of the latest advances in research and considerations for future directions to combat protein aggregation. “Protein Misfolding and Human Diseases" serves as an invaluable reference on the intricacies of protein misfolding and its clinical implications. It takes an interdisciplinary approach to the topic, integrating insights across biophysics, cell biology, structural biology, neuroscience and medicine. Researchers, academics and graduate students working across these fields will benefit from this comprehensive guide. Additionally, clinicians and healthcare professionals will find it invaluable for understanding the molecular basis of protein misfolding disorders. Pharmaceutical and biotechnology professionals involved in drug discovery and development targeting protein misfolding pathways will also benefit greatly.

  • Medical and Health Genomics of South Asia

    • 1st Edition
    • Dhavendra Kumar + 1 more
    • English
    Medical and Health Genomics of South Asia, a new volume in the Genomic and Precision Medicine in Clinical Practice series, offers a thorough discussion of medical genomics as applied across South Asian nations, from India to Pakistan, Bangladesh, Sri Lanka, and Nepal, as well as in South Asian populations abroad. Here, global chapter authors consider genomic variation and the population heterogeneity of genetic, infectious, and lifestyle diseases in South Asia, along with successful modes of population health management for these inherited disorders and other applications of clinical genomics for improved individual health in the region.Adopting an applied approach, this book first reviews basic genomic models and population study formats, as well as the anthropological and genetic history of South Asia. The following sections examine genomic epidemiology and population health in the South Asian context; examples of genomic medicine's use in combating major health challenges in the region; genomic healthcare infrastructure; and related social, ethical, legal, and economic aspects central to impactful genomic medicine.

  • Unlocking Sirtuins

    Cellular Biology to Translational Research
    • 1st Edition
    • Pranav Kumar Prabhakar + 1 more
    • English
    Unlocking Sirtuins: Cellular Biology to Translational Research explores the intricate roles of sirtuins, from basic principles to clinical significance. The book is organized into six parts, covering foundational concepts, roles in aging and metabolism, disease pathology, therapeutic strategies, future research directions and potential challenges. Topics include the structure and evolution of sirtuins, their mechanisms of action, and their impact on neurodegenerative diseases, cardiovascular health, and cancer. It also features detailed chapters on sirtuin modulators, drug discovery, the latest technologies and tools in the field, emerging trends, and the challenges, ethical considerations and future directions of sirtuin-targeted therapies. The content is complemented by case studies, clinical insights, and step-by-step procedures, offering a comprehensive and practical exploration of the subject. “Unlocking Sirtuins” offers an in-depth overview of sirtuin biology, bridging fundamental science with clinical application. It serves as an essential resource for researchers, clinicians, and advanced students working across cellular and molecular biology, biochemistry, pharmacology, aging, metabolic disorders, translational medicine and related fields.

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