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Elsevier

Books in Life sciences

  • Rehabilitation Engineering, Assistive Technologies and the Future of Healthcare Using Robotics

    • 1st Edition
    • D. Jude Hemanth + 1 more
    • English
    Rehabilitation Engineering, Assistive Technologies and the Future of Healthcare Using Robotics​​​ presents the most recent developments in assistive technologies, rehabilitative engineering, and robotics, offering in-depth analysis of cutting-edge instruments and frameworks that have the power to transform rehabilitation and general well-being. The book provides insights into how the integration of assistive technology and robots can enhance healthcare delivery while also addressing global challenges related to healthcare accessibility, rehabilitation, the integration of advanced technologies, opportunities, and problems in assistive technologies. Sections are complemented by case studies from different countries.

  • Translational Pulmonology

    • 1st Edition
    • English
    Translational research is essential to the advancement of medicine. Translational Pulmonology is an instructional guide to translational medical research serves as a practical, step-by-step roadmap for taking a biomedical device, potential therapeutic agent, or research question from idea through demonstrated clinical benefit. Fundamentally, the volume aims to help bridge the gap between current research and practice. Written by a team of expert medical, biomedical engineering, and clinical research experts in pulmonary diseases, this volume provides a clear process for understanding, designing, executing, and analyzing clinical and translational research within the field.

  • Innovations in Cardio-Oncology

    Artificial Intelligence, Digital Health, and Precision Medicine
    • 1st Edition
    • Sherry-Ann Brown
    • English
    Innovations in Cardio-Oncology: Artificial Intelligence, Digital Health, and Precision Medicine reviews the benefits of biomedical technologies and advancements in individualized medicine, with applications in cardio-oncology.Illu... of work involving machine learning and natural language processing help readers understand and maximize the benefits of artificial intelligence (AI) algorithms, with integration of AI and digital health technologies into the clinical workflow for personalized patient care, research, and provider and patient education.In 31 chapters, Innovations in Cardio-Oncology: Artificial Intelligence, Digital Health, and Precision Medicine introduces the emergent medical field at the interface of cardiology and oncology, “cardio-oncology”, and describes prevention, screening and surveillance, followed by several chapters on the role of the applications of digital health, telemedicine, and AI in cardio-oncology precision care. The book also highlights many medical society guidelines and evidence-based recommended pathways for equitable digital health deployment and utilization in cardio-oncology care. This book anticipates that AI algorithms and innovative health tools have the potential to address, and does not have to widen, the already existing healthcare disparities, including inequalities related to race, ethnicity, gender, socioeconomic level, health insurance status, linguistic and cultural barriers, systemic discrimination, and healthcare access.This book provides valuable practical guidance for healthcare professionals, scientists, learners, and patients to integrate digital health platforms into their clinical practice, research, and patient engagement models, fit for individual use and also for multi-stakeholder groups from academia, technology, and industry, with shared interests in applying Innovation (Digital Health, mHealth, Telemedicine, Telehealth, Informatics, Precision Health, Computational Medicine, Social Media, Artificial Intelligence including Machine Learning, Deep Learning, Natural Language Processing, and Neural Networks, & more) to Cardiology and Oncology clinical practice, research, and education.

  • Advances in DNA and mRNA-Based Strategies for Cancer Immunotherapy: Part A

    • 1st Edition
    • Volume 165
    • English
    Advances in DNA and mRNA-Based Strategies for Cancer Immunotherapy, Volume 165 in the Advances in Immunology series, presents current developments and comprehensive reviews in DNA and mRNA vaccines: Significant therapeutic approach against cancer management, Nanoparticles for mRNA-based cancer immunotherapy, Nucleic acid Delivery as a therapeutic approach in cancer immunotherapy, Plasmid DNA and mRNA: Delivery approaches and challenges, Viral & Non-viral Delivery of mRNA against Cancer Cell, Progress in Modifying and Delivering mRNA therapies for Cancer Immunotherapy, and more.Other chapters cover mRNA-Based Cancer Vaccines: A Novel Approach to Melanoma Treatment, Therapeutic mRNAs for cancer immunotherapy: from structure to delivery, Harnessing the immune system: Insights into cancer vaccines, Lipid Nanoparticle-Mediate... mRNA Delivery in Cancer Immunotherapy, Immunotherapy Perspectives in the Era of B-Cell Editing in Cancer Treatment, Personalized Precision: Revolutionizing Cancer Treatment with mRNA-Based Vaccines in Melanoma Therapy, Revolutionizing Cancer Treatment: Exploring Novel Immunotherapeutics, Checkpoints, bispecifics, and Vaccines in Development, and more.

  • Point-of-Care Technology for Portable Testing Devices

    Nanomaterials-Based Optical Biosensors for Cardiovascular Disease Biomarkers
    • 1st Edition
    • Tharmaraj Vairaperumal + 2 more
    • English
    Point-of-Care Technology for Portable Testing Devices: Nanomaterials-Based Optical Biosensors for Cardiovascular Disease Biomarkers presents the latest advances in nanomaterials-based optical biosensor-enabled point-of-care testing (PoCT) devices for the rapid and accurate detection of cardiovascular disease (CVD) biomarkers. This book begins with the introduction of novel cardiovascular biomarkers and advances in point-of-care diagnostics. Subsequent chapters focus on the selection of bioreceptors and the overview of optical nanomaterials for nanobiosensors applications.A major focus is targeted on colorimetric detection, fluorescence, chemiluminescence, Localized Surface Plasmon Resonance, and Surface-Enhanced Raman Scattering-based optical nanobiosensor signaling readout techniques, which enable the detection of CVD biomarkers. Furthermore, this book explores emerging healthcare technologies for next-generation portable PoCT devices and recent advances in nanobiosensor techniques for the rapid detection of CVD biomarkers. One dedicated chapter explores the role of artificial intelligence in enhancing point-of-care diagnostics for CVDs, while another addresses critical regulatory challenges and safety considerations in translating nanomaterial-based biosensors into clinical practice.

  • Application of Adult Stem Cells in Regenerative Medicine

    • 1st Edition
    • Farshid Sefat + 1 more
    • English
    Application of Adult Stem Cells in Regenerative Medicine offers a comprehensive overview of tissue engineering using adult stem cells to treat various disorders throughout the human body. The book introduces readers to adult stem cells, tissue engineering, and their application in regenerative medicine. It covers many new and up-to-date techniques, providing a solid foundation for understanding the field. Written by global leaders, this resource is invaluable for anyone studying, researching, or working in the areas of adult stem cells, tissue engineering, or regenerative medicine.The book is divided into three parts. Part One provides an introduction to adult stem cells and their application in regenerative medicine. Part Two focuses on different body organ systems, including the nervous, respiratory, digestive, urinary, circulatory, endocrine, skeletal, reproductive, muscular, and ocular systems. Part Three concludes with a review of the future of adult stem cells in regenerative medicine. This structure ensures that readers gain a thorough understanding of the current state and future potential of adult stem cells in treating various disorders.

  • Sustainable Applications of Pomegranate Peels

    • 1st Edition
    • Mejdi Jeguirim + 1 more
    • English
    Sustainable Applications of Pomegranate Peels serves as an invaluable resource to enhance pomegranate farming and fruit processing industries while minimizing environmental impacts. The book delves into multiple sustainable applications, spanning biotechnological, agricultural, environmental, and energy sectors. It provides in-depth identification, quantification, and characterization of pomegranate wastes along with their potential in livestock breeding. Notably, it explores the use of bioactive compounds from by-products in food products, and details pomegranate's health benefits, including antioxidant and antimicrobial properties. This comprehensive guide is essential for researchers, decision-makers, and industry professionals.

  • Additive Manufacturing Solutions for Advanced Veterinary Practice

    Clinical Dentistry, Orthopedic, and Drug Delivery Methods
    • 1st Edition
    • Rupinder Singh + 2 more
    • English
    Additive Manufacturing Solutions for Advanced Veterinary Practices: Clinical Dentistry, Orthopedic, and Drug Delivery Methods highlights cost- and time-saving 3D printing methods and materials for application on a broad array of veterinary patients and procedures. Additive manufacturing of sensors, biodegradable dental implants, smart dental implants, joint implants, and drug-delivery materials are each covered, as are biomimetic, augmented reality, and virtual reality approaches. Varied additive manufacturing processes and techniques are covered, with each chapter including at least one case study that shows the material covered being put into practical use.

  • Non-thermal Processing of Major Food Macromolecules

    • 1st Edition
    • Seid Reza Falsafi + 2 more
    • English
    Non-thermal Processing of Major Food Macromolecules provides comprehensive knowledge on state-of-the-art approaches utilized to process foods and/or modify their physicochemical structural – along with the technofunctional attributes of food macromolecules (i.e., protein, starch, lipids) – through novel non-thermal processing techniques. Sections explore the impact of non-thermal processing on proteins, starches, and on lipids and present the challenges for the food application of non-thermal processing treatments, thus suggesting how to push the food application of these architectures forward around the world.Edited by a team of experts in the field, this book is a great resource for researchers and industry personnel working in the various fields of non-thermal processing treatments, particularly in the food areas.

  • The Neuroscience of Feelings

    Unveiling the Mind-Brain Alchemy
    • 1st Edition
    • Volume 293
    • English
    The Neuroscience of Feelings: Unveiling the Mind-Brain Alchemy focuses on exploring the complex interplay between emotions and brain function, covering topics such as how positive and negative feelings impact brain cell regeneration, the influence of emotions on decision-making, and the role of emotional trauma in brain health. The book aims to provide comprehensive insights into how different emotions shape neurological processes, contributing to mental and physical health.

  • Microbiome in Neurological Conditions: Biology, Mechanisms, and Diagnostic Approach

    • 1st Edition
    • Volume 180
    • English
    Microbiome in Neurological Conditions, Volume 180, the latest release in the International Review of Neurobiology series, highlights advances in the field, with this volume presenting insightful chapters written by an international board of authors. Chapters in this volume include Dysbiosis significantly elevates the probability of altered affective function in Alzheimer's Disease (AD), Intestinal Dysbiosis leads to reduction in Neurochemical production in Parkinson’s Disease (PD), Microbiota dysbiosis impact on the immune system dysregulation in Huntington's disease (HD), Altered microbiome influence on the enteric neuromuscular system in Amyotrophic Lateral Sclerosis (ALS), Oro-pharyngeal mucosal microbiome alterations causing immune system dysregulation in Schizophrenia, and much more.Other chapters cover Disruption in the human microbiome causing behavioral changes in Bipolar Disorder, The role of Microbiome in Gut-Brain-Axis dysbiosis causing Depression: from Mechanisms to Treatment, Microbial imprints: The role of secondary genomes in neurodevelopment and co-evolutionary dynamics, Abnormal microbiota due to perinatal antibiotic exposure as a possible risk factor for Attention-Deficit / Hyperactivity Disorder (ADHD), Microbiome-based dietary supplements for better development and a healthy brain, Bacterial meningitis as a significant catalyst for neuroinflammation, and more.

  • Music and Dementia

    Theory and Implications for Music Use in Dementia Care
    • 1st Edition
    • Sandra Garrido
    • English
    Music and Dementia: Theory and Implications for Music Use in Dementia Care presents research on the effect of music on the brain for neurodegenerative diseases and care. This volume examines the neurological impact of music from research to clinical application, offering case studies and practical steps. This book will be of interest to researchers in dementia and neurodegeneration, as well as practitioners and clinicians interested in the therapeutic application of music in dementia care.

  • Encyclopedia of the Eye

    • 2nd Edition
    • Patricia D’Amore
    • English
    Encyclopedia of the Eye, Second Edition, Four Volume Set is an important resource for all visual scientists, ophthalmologists, and optometrists, as well as researchers in immunology, infectious disease, cell biology, neurobiology, and related disciplines. This four-volume reference is unique in its coverage of information on all tissues important for vision, including the retina, cornea, and lens. The book also covers the physiological and pathophysiologic processes that affect all eye tissues. Each chapter addresses one specific structure or process, reviews basic concepts, cross-references other chapters within the Encyclopedia, and provides citations of relevant primary publications.It is an invaluable resource for undergraduate students, graduate students, postdoctoral fellows, medical students, and residents seeking an introduction to an area of eye research. It will be particularly useful for visual scientists and practitioners who are investigating a new area, seeking deeper understanding of important research articles in fields adjacent to their own, and/or reviewing a grant or manuscript outside their immediate area of expertise.

  • Formation and Fate of Cell Organelles

    • 1st Edition
    • Katherine Brehme Warren
    • English
    Formation and Fate of Cell Organelles is a collection of papers that discusses the manner in which cellular structures arise from the component molecules, particularly on cytoplasmic inheritance, and the problem of spontaneous assembly. One paper describes the process how the phospholipid lecithin, assemble spontaneously into complex structures with great versatility when the lipid molecules are dispersed in an aqueous environment in vitro. Another paper discusses the resolution of the spindle fibers of the mitotic apparatus where the major protein in the apparatus is a 3.5 S particle, with a molecular weight of ca. 68,000. One paper investigates the degree of organization in the bacterial cell where inside the bacterial cell, the DNA act as its own method of compartmentation. Possibly, the DNA forms a coil which contains the mechanisms for the synthesis of the deoxy triphosphate into DNA. The coil leaves none of the mechanisms for the normal metabolism of the cell nor the mechanisms for the formation of RNA. Another paper examines cytoplasmic genes and organelle formation. The collection can prove valuable for bio-chemists, cellular biologists, micro-biologists, and developmental biologists.

  • Microbial Inoculants

    Soil Dynamics and Nutrient Bioavailability
    • 1st Edition
    • Ajay Kumar + 3 more
    • English
    Microbial Inoculants: Soil Dynamics and Nutrient Bioavailability is an essential volume in the Plant and Soil Microbiome series. This book delves into the foundational and contemporary details regarding the use of microbial inoculants, which are living organisms like fungi, bacteria, and microalgae, sourced from soil, plants, water, and organic materials. Acting as biostimulants or biocontrol agents, these inoculants offer an environmentally-frie... alternative to synthetic fertilizers and pesticides, playing a crucial role in soil conservation, plant health, and crop yield enhancement.Apart from exploring the nexus between plant and soil, the book also discusses the range of applications of microbial inoculants in agricultural and environmental practices. It provides insights into how these microorganisms contribute to sustainable farming by enhancing nutrient bioavailability and protecting crops from diseases, thus promoting better yield and overall plant vitality. This volume is a valuable resource for those interested in advancing agricultural techniques through the utilization of natural, biotic solutions.

  • Novel Genetic Pathways Associated to Energy Homeostasis Impairments

    • 1st Edition
    • Volume 113
    • English
    Novel Genetic Pathways Associated to Energy Homeostasis Impairments, Volume 113 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Advances in Metabolism: Energy Balance Circuitry, Advances in Metabolism: Diabetic Retinopathy, From Metabolomics to Energy Balance Physiology, Advances in Metabolism: Prader-Willi Syndrome, Neural Mechanisms and Health Implications of Food Cravings During Pregnancy, Advances in Metabolism: Diabetes, Advances in Metabolism: Cachexi, and Parkinson’s Disease and Metabolic Disorders: Understanding Their Shared Co-Morbidity Through the Autonomic Nervous System.

  • Blindness and Visual Impairments

    • 1st Edition
    • Volume 292
    • English
    Blindness, Volume 292 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Temperature as a circadian timing cue in the visually impaired, Visual experience affects neural correlates of audio-haptic integration: A case study of non-sighted individuals, Visual experience affects neural correlates of audio-haptic integration: A case study of non-sighted individuals, Measuring residual visual function after cerebral damage – a potential path for optimizing rehabilitation approaches, and Persistence of training-induced visual improvements after occipital stroke, amongst other topics.Other chapters in this release include Well-being, mental health, and sleep in children and young people with vision impairment: A narrative review, Changes to the brain due to visual impairment, Information Processing in People with Visual Impairments, Case studies of the migraine aura in the blind or partially sighted, HABEMO: an innovative haptic tool for investigating the bodily representation of mental states in individuals with visual impairments, and Affect in the dark: navigating the complex landscape of social cognition in blindness, and An overview of quality of life and visual outcomes in AMD.

  • Raising Genomics Literacy, Knowledge, and Awareness

    • 1st Edition
    • Azhar T. Rahma + 1 more
    • English
    Raising Genomics Literacy, Knowledge, and Awareness is a unique resource which describes the importance of genomic literacy for the effective and streamlined implementation of genomic medicine and pharmacogenomics globally. It provides evidence and expert opinion to decipher the role of genomic and pharmacogenomic literacy to illustrate the evidence, value, and need of raising genomics awareness and education among healthcare professionals, students, and the general public. This text can be used by researchers and graduate students pursuing research in this area.

  • Anti-Prostate Cancer Agents

    • 1st Edition
    • Qiao-Hong Chen
    • English
    Anti-Prostate Cancer Agents walks the readers through the anti-prostate cancer drug development pipeline from early discovery/design to clinical studies/applications... This book covers discovery/design, synthetic studies, preclinical evaluation, mechanism of action, structure-activity relationships, clinical studies/applications of anti-prostate cancer agents.This book provides insight on how the design and discovery process of anti-prostate cancer agents have evolved from androgen deprivation therapy to current androgen receptor antagonists/degrader... So far, no book focusing on the topic has been published.

  • Structural Inequalities and Health Outcomes for Chronic Disease

    • 1st Edition
    • Leonard E. Egede
    • English
    Structural Inequalities and Health Outcomes for Chronic Disease provides a conceptual framework for understanding existing evidence and guides the research around promising interventions and policies. In addition, it demonstrates how structural inequalities impact health and presents ways the healthcare system can participate in the solution. The book covers major chronic diseases and the special populations impacted by structural inequalities. Those working and studying public health, medicine, nursing, pharmacology will find this work of interest, as well as diversity and disparity scholars and health policymakers.

  • Circadian Rhythms in Health and Disease

    • 1st Edition
    • Volume 393
    • English
    Circadian Rhythms in Health and Disease, Volume 393 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Circadian Rhythms in Cardiac Health and Disease, Liver as a nexus of daily metabolic cross talk, Non-rhythmic modulators of the circadian system: A new class of circadian modulators, The emerging role of circadian rhythms in exosome-mediated cellular crosstalk, Circadian rhythms and muscle health, and Output circuits from the suprachiasmatic nucleus controlling diverse physiological functions.

  • Ligands for Targeted Drug Delivery

    Basic Fundamentals and Applications
    • 1st Edition
    • Vikas Pandey + 3 more
    • English
    Ligands for Targeted Drug Delivery: Basic Fundamentals and Applications is a comprehensive reference focused on the many ways drug carriers can be functionalized to target specific organs, tissues, cells, and sub-cellular compartments. Chapters cover the basic concepts of targeted drug delivery, describing multiple levels of targets and challenges, along with approaches for target-specific drug delivery and a thorough overview of the challenges in design and application of ligands. Following sections discuss nanoparticles and the main ligand classes with their respective applications. The final chapters discuss future prospects of the technology and clinical aspects of ligand modified drug delivery systems.This is a key reference to drug delivery researchers dealing with the application of ligands to overcome challenges in delivering their active principles to the target structure. Biomedical engineers, materials scientists, and chemists can also benefit from the through description of ligand classes and their potential to improve drug delivery efficiency.

  • Lung Cancer and Environmental Toxicants

    • 1st Edition
    • Kamal Dua + 4 more
    • English
    Lung Cancer and Environmental Toxicants aims to explore the intricate relationship between lung cancer and environmental toxicants, shedding light on a hidden link that demands urgent attention. This groundbreaking book addresses a critical gap in the current literature by introducing a pioneering exploration of the interplay between lung cancer and environmental toxicants. Previous articles have not coalesced into a comprehensive examination of the complex connection between lung cancer development and the diverse array of environmental toxicants. This book delves into the latest scientific research and clinical findings to offer a clear way forward for healthcare workers to assess and treat lung cancer patients who may have been exposed to these substances. "Lung Cancer and Environmental Toxicants" provides a precise view of the impact of environmental toxicants on lung cancer, covering various aspects including epidemiology, molecular mechanisms, exposure pathways, and preventive measures. This unique and timely work will pave the way for a deeper understanding of the underexplored factors contributing to lung cancer incidence, offering novel insights into the role of various toxic substances in disease causation. This significant title will catalyze new avenues of research and awareness in the fields of oncology, environmental health, and public policy.

  • Biomarker Landscape in Cancer Research

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Biomarker Landscape in Cancer Research examines the impact of early detection, predication of aggressiveness, and the determination of the best treatment for cancers. With a strong focus on the status, challenges, and prospects of biomarker measurements' tools and technology, the book also examines clinical translation-related knowledge and the prognosis of different organ related cancers. In 21 chapters, it describes current and new diagnostic tools in twenty different cancers and explores how innovations in the cancer diagnostic space could make cancer screening and early detection more straightforward.This book is a timely and valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 86
    • English
    Advances in Microbial Physiology, Volume 86, the latest release in this ongoing series, continues the tradition of topical, important, cutting-edge reviews in microbiology. The editors have always strived to view microbial physiology in the broadest sense. In this volume, chapters deal with Diversity in the physiology and metabolism of chlorophototrophic bacteria, Copper homeostasis in Streptococcus and Neisseria: known knowns and unknown knowns, A Lysis Less Ordinary: The Bacterial Type 10 Secretion System, Cytochrome bd-type oxidases and environmental stressors in microbial physiology, and Multiple roles for iron in microbial physiology: bacterial oxygen sensing by heme-based sensors.

  • Parkinson's Disease, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 43-2
    • Joseph Jankovic
    • English
    In this issue of Neurologic Clinics, guest editor Dr. Joseph Jankovic brings his considerable expertise to the topic of Parkinson's Disease. Top experts cover key topics in the field, including James Parkinson and other historical aspects of Parkinson’s disease; precision medicine in Parkinson’s disease; prodromal Parkinson’s disease; biomarkers in Parkinson’s disease; disease-modifying therapies in Parkinson’s disease; and many more.

  • The Living Laboratory for Precision Medicine

    Solutions for Clinical Implementation
    • 1st Edition
    • Dame Anna Dominiczak + 2 more
    • English
    The Living Laboratory for Precision Medicine: Solutions for Clinical Implementation provides a comprehensive resource on precision medicine through a convergence of innovation and solutions across multiple domains, including large population cohorts, artificial intelligence, genomics, phenomics, clinical trials, health economics and regulation exemplified by the living lab concept. This book is the first to look at precision medicine through the lens of last-mile solutions which make it broad in scope, practically relevant, and cutting-edge. The book explores the use of precision medicine to stimulate regional economic growth through a healthier population, savings on healthcare, and using innovation as a driver of economic development. The term precision medicine has been popularized by clinical, scientific, political, financial and technological interests as the biggest innovation to revolutionize healthcare. While over the past decade a few precision medicine-based solutions have come to fruition, the transformative leap in healthcare delivery and population benefit is yet to be realized. Current focus on precision medicine primarily focuses on patient stratification which constrains it to either a single disease area, a few sub-disciplines, or using a limited set of genomic technologies. While useful, experience over the last few years indicates precision medicine needs to be considered as a complex process with multiple feedback loops requiring significant interdisciplinary collaboration and innovation.

  • Diabetes Mellitus

    Target Enzymes and Drugs
    • 1st Edition
    • Manisha Nidhar + 1 more
    • English
    Diabetes Mellitus: Target Enzymes and Drugs highlights the importance of different targets in lead drug discovery and the importance of the synthesis of lead analogues. The book discusses the role of target enzymes, receptors, and related drugs in diabetes mellitus that are necessary for research on improving solutions for diabetes care. This unique resource provides information about all enzymes or receptors involved in diabetes pathophysiology to help describe target enzymes and potent antidiabetic drugs to improve patient care.This type of research is needed for the understanding of the effects of drugs in order to improve future treatments and care of patients with diabetes.

  • Exploring Noninvasive Disease Biomarkers with Urinary Omics Analysis

    • 1st Edition
    • Arup Giri + 2 more
    • English
    Exploring Noninvasive Disease Biomarkers with Urinary Omics Analysis offers a transformative journey into the world of non-invasive diagnostics. This comprehensive volume delves into the molecular foundations of urinary biomarkers, illuminating the intricate signatures that indicate various pathological conditions and elucidating the mechanisms behind their release into urine. Readers will gain invaluable insights into cutting-edge analytical technologies, methodologies, and data integration techniques essential for biomarker discovery. From genomic approaches to transcriptomics, proteomics, and metabolomics, each chapter provides a thorough examination of the latest advancements, accompanied by practical guidance and case studies showcasing their clinical applications across diverse health conditions.In addition to the foundational knowledge, the book highlights the clinical applications of urinary omics in diagnosing renal disorders, metabolic syndromes, and infectious diseases. It equips professionals and students with the tools needed to navigate the complexities of urinary omics, revolutionize personalized medicine, and advance transformative healthcare solutions. The practical guidance and case studies included in the book make it an invaluable resource for those looking to implement these advanced diagnostic techniques in clinical settings.

  • Neuropathology of Aging and Alzheimer’s Disease

    • 1st Edition
    • Rudy J. Castellani
    • English
    Neuropathology of Aging and Alzheimer’s Disease takes a foundational approach to the topic by offering basic scientific information and the latest advancements in the field. The focus of this reference is on neuropathology and recent advances in tissue characterization in aging, and in Alzheimer’s Disease. Neuropathology has direct relevance to therapeutic constructs and allows for an in-depth understanding of disease pathogenesis. It is a synthesis of the salient issues with respect to pathology, pathogenesis, diagnosis, disease, normal aging, biomarker relevance, and prospects for therapeutic intervention.

  • Carbohydrate Nutrition

    • 1st Edition
    • Bin Zhang + 1 more
    • English
    Carbohydrate Nutrition discusses the nutritional functionality of foods in addressing the current metabolic disease epidemic. It begins by introducing the sources and structures of various carbohydrates, including starch, human milk oligosaccharides, polyols, arabinoxylan, beta-glucan, and cellulose, along with their function in the small intestine and colon. The book offers a comprehensive examination of carbohydrates, covering their chemistry, classification, digestion and health implications. The importance of prebiotic carbohydrates, such as human milk oligosaccharides and dietary fibers like cellulose, arabinoxylans, and beta-glucan is also discussed.Each chapter is authored by leading experts in the field making Carbohydrate Nutrition is a valuable resource for nutrition researchers, food scientists, food chemists, and those studying related topics. Readers can apply these insights to the design and development of foods with improved carbohydrate nutrition.

  • The Epidemiology and Prevention of Childhood Injuries

    An Overview
    • 1st Edition
    • Hamid Soori + 1 more
    • English
    The Epidemiology and Prevention of Childhood Injuries: An Overview takes a comprehensive approach to understanding and addressing childhood injuries. Integrating global research and practice, the book aims to significantly advance injury prevention among children. With detailed chapters on epidemiological measures, risk factors, and prevention strategies, it offers a thorough review of childhood injury contexts. The book covers injuries related to transport, home, school, play, sports, workplace, violence, and disasters. It discusses first aid essentials, accountability, and collaboration, concluding with methodologies, data collection techniques, and outcome assessments. This resource is invaluable for researchers, pediatricians, public health experts, and policymakers seeking to protect children.

  • Advances in Agronomy

    • 1st Edition
    • Volume 192
    • English
    Advances in Agronomy, Volume 192, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors. Chapters in this new release include The USDA Desert Soil-Geomorphology Project (1957-1972), Electrochemical transformations of nutrients in the soils vis-a-vis geochemistry of potentially and readily available nutrients under different soil moisture regimes: a review, Current approaches in the characterization and quantification of soil crusts, Soil fauna impacts on carbon cycling in managed grasslands: a review, Deciphering PGPR Mechanisms in Saline Soils: Enhancing Plant Productivity, and much more. Other chapters cover Interventions of microbial fuel cell technology for management of agricultural residues: Challenges and future perspectives.

  • Enzymes of Polyamine Metabolism

    • 1st Edition
    • Volume 715
    • English
    Enzymes of Polyamine Metabolism, Volume 715 highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Convergence of MYC and the hypusine circuits in the control of metabolism, HDAC10 structure and enzymology, TR-FRET Assay for Profiling HDAC10 Inhibitors and PROTACs, Polyamine Transport Inhibitors: Methods and caveats associated with measuring polyamine uptake in mammalian cells, Evaluation of platinum drug toxicity resulting from polyamine catabolism, Measurements of acrolein adducts resulting from polyamine catabolism, Alterations in polyamine metabolism induced by the pathogen Helicobacter pylori: implications for gastric inflammation and carcinogenesis, and much more.Other sections delve into Molecular and biochemical analysis of eIF5A, Analysis of in vivo SMOX activity, Structure and role of ATP13A2 in polyamine transport, Analysis of Translational Regulation Using Polysome Profiling and Puromycin Incorporation, Targeting polyamine metabolism in an ex vivo prostatectomy model, Development and characterization of a Drosophila model of SRS, Monitoring ODC activity and polyamines in Bachmann-Bupp syndrome patient biological samples, Gene replacement therapy to restore polyamine metabolism, Investigation of polyamine metabolism in bone homeostasis, Collection, preparation, and biobanking of clinical specimens for polyamine analysis, and many other topics.

  • Biosafety Level 4 (BSL4) – Virus Research at the Highest Level of Biosafety and Biosecurity

    • 1st Edition
    • Volume 121
    • English
    Biosafety Level 4 (BSL4) – Virus Research at the Highest Level of Biosafety and Biosecurity, Volume 121 highlights new advances, with this new volume presenting interesting chapters on highly important topics such as Molecular virulence determinants of human-pathogenic filoviruses, Mucosal Sudan virus infection results in a lethal disease in ferrets with previous Lloviu virus infection not providing cross-protection, Transcriptional signatures of Ebola and Marburg virus infection in a Bat-Immune-System (BIS) mouse model, Divergences in the microbial inactivation pattern between vaporized hydrogen peroxide and aerosolized peracetic acid by dry fogging, and much more.Other chapters cover Molecular expressions in tissues and blood following Reston and Bundibugyo virus infection in swine, De novo rescue of new BSL4 henipaviruses - from sequence to pathogen, Semi-automated diagnostic RT-PCR as a screening assay for antiviral compounds in a 96-well format against highly pathogenic RNA viruses, and Relevance of studying virus – natural reservoir interactions: SNV in deer mice and LASV in Mastomys natalensis.

  • Biochemical Aspects of Metabolic Disorders

    • 1st Edition
    • Muhammad Sajid Hamid Akash + 1 more
    • English
    Biochemical Aspects of Metabolic Disorders offers a comprehensive exploration of the intricate biochemical mechanisms and/or pathways underlying a wide array of metabolic disorders. From the genetic basis of inherited metabolic conditions to the environmental factors impacting metabolic dysregulation, each chapter investigates the molecular insights essential for understanding and managing these complex diseases. Covering topics such as carbohydrate and lipid metabolism disorders, amino acid catabolism, hepatic and renal metabolism, mitochondrial dysfunction, pediatric obesity, and diagnostic approaches, this book will serve as a requisite resource for researchers, clinicians, and students alike looking for unravel the biochemical intricacies of metabolic disorders.

  • Culinary Nutrition

    The Science and Practice of Healthy Cooking
    • 2nd Edition
    • Jacqueline B. Marcus
    • English
    Culinary Nutrition: The Science and Practice of Healthy Cooking, Second Edition is one of the first textbooks specifically written to bridge the relationship between food science, nutrition, and culinology as well as consumer choices for diet, health, and enjoyment. The book uses a comprehensive format with real-life applications, recipes, and color photographs of finished dishes to emphasize the necessity of sustainably deliverable, health-beneficial, and taste-desirable products.The book includes pedagogical elements to enhance and reinforce learning opportunities; explores which foods and beverages involve the optimum nutritional values for dietary and health needs; includes specific dietary requirements throughout the lifecycle; and examines how foods and beverages are produced. The fully revised second edition includes updated dietary and health guidelines and recommendations; more vegan, vegetarian, and plant-based meals; updated protein, carbohydrate, fat, vitamin and mineral recommendations; environmental and sustainability considerations; and much more.

  • Disparities in Pediatric Endocrine Disorders, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 54-2
    • Terri H. Lipman + 1 more
    • English
    In this issue of Endocrinology and Metabolism Clinics, guest editors Drs. Terri Lipman and Ingrid Libman bring their considerable expertise to the topic of Disparities in Pediatric Endocrine Disorders. Top pediatric endocrine experts discuss health disparities present in pediatric endocrinology and metabolism care, with the goal of achieving more equitable patient care in the areas of diabetes, bone disease, puberty, and thyroid disease, and more.

  • Molecular Medicine and Biomedical Research in the Era of Precision Medicine

    New Technologies and Personalized Drug Therapies for Patient Care
    • 1st Edition
    • Ranbir Chander Sobti + 4 more
    • English
    Molecular Medicine and Biomedical Research in the Era of Precision Medicine: New Technologies and Personalized Drug Therapies for Patient Care provides researchers with an extensive overview of recent advances in molecular biology impacting the development of targeted therapies. The book delivers insights into the pathobiological and pathogenetic mechanisms of various diseases, providing a detailed study of the latest personalized interventions to be implemented across such conditions. It covers a range of technologies, including RNA-sequencing, AI, Machine Learning, gene therapy, omics and nanotechnology, delving into their clinical applications across various diseases.The book also tackles targeted treatments of different disease types, including acute, chronic, infectious and noncommunicable diseases. Future perspectives are also covered, providing an in-depth study across molecular medicine, drug discovery and delivery, disease diagnosis and prevention, and therapeutic interventions, and acting as an invaluable interdisciplinary reference for researchers across the biomedical sciences.

  • Patient Safety and Health Care Quality in Vulnerable Hospitalised Populations

    • 1st Edition
    • Theresa A. Mikhailov
    • English
    Patient Safety and Health Care Quality in Vulnerable Hospitalised Populations consolidates existing knowledge and research on patient safety and healthcare quality within vulnerable populations. It provides a comprehensive reference work, offering invaluable insights into this critical area. While information on related topics is scattered across various medical journals, this book bridges the accessibility gap by bringing this knowledge together in one authoritative volume. With a specific focus on hospitalized children and elderly adults, the book tackles a global issue that is particularly relevant in low-resource settings.In addition, it endeavors to address the unique challenges confronted by these populations, equipping stakeholders with vital information and strategies to better serve them. By exploring patient safety and healthcare quality, users will find this to be an invaluable resource that will shape the future of care provision for vulnerable populations.

  • Handbook of Milk Production, Quality and Nutrition

    • 1st Edition
    • Tanmoy Rana
    • English
    Handbook of Milk Production, Quality and Nutrition emphasizes new applications to promote healthy milk production, processing, and product development in the milk industry, highlighting the role clean milk has in the prevention of health and disease. Sections cover the general aspects of milk production and its environmental impact on animal health, explain milk’s global nutritional appeal and its role as a source of both macro and micronutrients for human health, address issues of lactose intolerance and how this ailment is perceived globally, and discuss milk’s relevance on bone, ocular, and gut health.Finally, the book brings awareness to milk’s microbial pathogens, toxins, and heavy metals, and health concerns, while also updating on regulatory health and nutrition claims and recent legislative developments.

  • Roles of Osmolytes in Changing Environment

    • 1st Edition
    • Azamal Husen
    • English
    Roles of Osmolytes in Changing Environment is the only available comprehensive coverage of the recent advances in our understanding on how plants coordinate with different osmolytes, and their role in improving the tolerance of plants under stress conditions. Including insights of their effect against cold, heat, UV, submergence, wounding, extremes of temperature, drought, salinity, high metal concentrations, water logging, pollution, and nutrient deficiency stress, the book also explains the role of various osmolytes against phytopathogenic viruses, bacteria, fungi, algae, nematodes, and insects. Understanding the significance of different osmolytes for sustainable plant growth and production under diverse stress situations is increasingly important for both crop and non-crop plants. This volume presents the latest research and inspires further research toward osmolyte use in developing stress tolerance in plants. Roles of Osmolytes in Changing Environment is a valuable resource for scientists, researchers and advanced level students working in plant biology, plant physiology, plant stress physiology, plant biochemistry, botanical or crop sciences, environmental sciences, and ecological sciences.

  • Ultra Widefield Imaging of the Retina

    • 1st Edition
    • Maria Vittoria Cicinelli + 1 more
    • English
    Ultra Widefield Imaging of the Retina covers basic anatomy and physiology of the retina, providing the technical aspects of ultra widefield retinal imaging that give readers a strong grounding in the discipline’s central tenets. The book provides a comprehensive view of the peripheral retina, enabling better detection of pathology and more accurate assessment of disease progression. It fills the knowledge gap among healthcare professionals with regard to principles, procedural aspects, and clinical applications of these innovations. In essence, anyone seeking in-depth information on imaging and the treatment of vascular chorioretinal disorders, inflammatory disorders, and chorioretinal tumors will find it here.New imaging modalities, improved image quality, and enhanced analysis techniques have proven valuable tools in the diagnosis and management of retinal diseases, hence this book will serve as a resource for clinicians and researchers to stay up-to-date in this rapidly evolving field.

  • Veterinary Toxicology

    Basic and Clinical Principles
    • 4th Edition
    • Ramesh C. Gupta
    • English
    Veterinary Toxicology: Basic and Clinical Principles, Fourth Edition is a unique single reference that provides a comprehensive overview on the basic principles of veterinary toxicology to any student at the DVM, MS, or PhD level while also continuing to serve as a clinical reference for practitioners. The book thoroughly updates toxicologists and advanced students on the newest approaches for diagnosing poisoning cases in all animals from chemicals, plants, and accidental or malicious intents. Many chapters are provided on topics not covered in any previous books, such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology.Completel... revised and updated to include the most recent developments in the field animal toxins, toxicokinetics mechanism of action, toxicity, and treatment, this book is an essential resource for researchers, practicing veterinary toxicologists, advanced students in toxicology, poison control centers, as well as environmentalists, marine biologists, and animal scientists.

  • Biocatalysis

    • 1st Edition
    • Volume 714
    • English
    Biocatalysis, Volume 714 provides a wide range of themes dealing with the identification and application of biocatalysts. This includes various formats such as whole-cell or cell-free biocatalysis as well as immobilized variants. Specific chapters in this new release include Biocatalysis: How to select the proper mode of application, Documentation in biocatalysis and data handling, Mining metagenomes from extremophiles as resource for novel glycoside hydrolases for industrial applications, Functional Metaproteomics, Sequence-function relation for the prediction of enzyme properties: A case study on flavin-dependent oxidases, P450 monooxygenase in whole-cell format, and more.Additional sections cover Regio- and Stereospecific oxidation based on di-iron monooxygenases producing whole cells, Recombinant enzyme expression and targeted mutagenesis in Aromatoleum species, C.necator as a model organism for CO2-based biotechnology, Cupriavidus in whole-cell biocatalysis, Whole-cell biocatalysis with Myxobacteria, Streptomyces for natural product formation: Targeted mutagenesis in PKS, Reductive Amination: Methods for cell-free and whole-cell biocatalysis, Challenges and good practices on transaminase-catalys... synthesis of optically pure amines, W-enzymes in biocatalysis: Chances and difficulties for the user, Atroposelective biocatalysis employing ADHs, Applications of alcohol oxidases, and much more.

  • Clinical Pathophysiology of Hypertension, Diabetes, and Other Stress and Lifestyle Associated Diseases

    • 1st Edition
    • Tetsuya Watanabe
    • English
    Clinical Pathophysiology of Hypertension, Diabetes, and Other Stress and Lifestyle Associated Diseases presents mathematical and physical basis to apply in practice for a better understanding of some common and not so common diseases brough on by stress and lifestyle. Chapters cover new findings in hypertension, arrhythmias, diabetes, nephropathy, and periodontal disease. Written by Dr. Tetsuya Watanabe, President of Watanabe Institute of Mathematical Biology and Watanabe Clinic of Oral Surgery in Hamamatsu, Japan, for clinical doctors, medical research doctors, pathophysiological scientists, pharmaceutical scientists, and biologists and physicists in bioengineering.

  • Nutrición y dietética clínica

    • 5th Edition
    • Jordi Salas-Salvadó + 1 more
    • Spanish
    Nutrición y dietética clínica se consolida en esta quinta edición como una obra esencial para los profesionales de la salud por su enfoque riguroso y multidisciplinar sobre el tratamiento dietético de las enfermedades relacionadas con la alimentación. Destaca el carácter colaborativo de la obra y su alcance global, ya que cuenta con la experiencia de más de 100 autores españoles e hispanoamericanos, todos ellos médicos, dietistas-nutricioni... o profesionales de otras especialidades relacionadas con la alimentación y la nutrición. Una importante novedad en esta edición es la introducción de un capítulo sobre trastornos de la conducta alimentaria, así como un anexo titulado «Nombres de alimentos en países de habla hispana» que, sin duda, apoya la consolidación de la proyección internacional de este texto, especialmente en países de América Latina, respetando la diversidad cultural y lingüística utilizando los términos propios de cada región para facilitar la compren­sión global. Los directores de la obra, el Prof. Jordi Salas-Salvadó y la Dra. Nancy Babio, junto con las Dras. Anna Bonada, M. Engràcia Saló y Rosa Burgos, y el Dr. Guillermo Cárdenas, han liderado este proyecto con dedicación y compromiso, asegurando la calidad y el rigor científico que han caracterizado Nutrición y dietética clínica desde la primera edición. La nueva edición ofrece acceso al e-book en el que se incluyen preguntas de autoevaluación con respuestas razonadas para fomentar la reflexión y evaluar la comprensión de los contenidos.

  • Sustainable Goat Production in the Changing Climate

    • 1st Edition
    • Veerasamy Sejian + 2 more
    • English
    Sustainable Goat Production in the Changing Climate aims to make the global scientific and academic communities aware of the potential of goats as a livestock of the future. When compared to more popular meat sources like cattle and swine, goats have a lower carbon footprint and can aid in mitigating the effects of climate change, as well as improving food production, poverty and equity issues. This book will discuss the implications of climate change on goat production systems and emphasize the physiological potential of goats to adapt to erratically changing climatic conditions. Furthermore, the book includes chapters on strategies to mitigate the effects of climate change on goat production and highlights novel technologies used to assess the impact of heat stress in goats. Technology transfer strategies and policy-related issues will also be covered.Written and edited by an international team of experts on goats, livestock, animal agriculture, and climate-smart food systems, Sustainable Goat Production in the Changing Climate will appeal to a broad audience, from researchers to livestock specialists, veterinarians, and policymakers in food and sustainability.

  • Small Ruminant Welfare, Production and Sustainability

    • 1st Edition
    • Govind Kannan
    • English
    Small ruminant production, particularly that of sheep and goats, has steadily increased over the years, with goat production alone doubling during the past three decades. Increased public attention to the impact of livestock management methods on animal well-being warrants rigorous research and dissemination of findings to address this issue. Small Ruminant Welfare, Production, and Sustainability focuses on advances in assessing and improving small ruminant well-being and the implications for the sheep and goat sectors worldwide. A variety of assessment systems for small-ruminant wellbeing are considered, including behavior, health, physiology, immunology, productivity, product quality, neural networks, thermal imaging, facial recognition, and artificial intelligence. Current methods and novel management practices are examined as they relate to both animal welfare and improvement of production systems.Small Ruminant Welfare, Production, and Sustainability is a welcome addition to the current body of work the current body of work on small ruminant management systems and welfare. Researchers in the fields of animal science, agricultural science, neuroscience, ethics and veterinary medicine, as well as stakeholders in the small ruminant industry and policymakers will benefit from this multidisciplinary resource.

  • Cholinergic Involvement in Neurodegenerative Diseases

    • 1st Edition
    • Volume 211
    • A. Claudio Cuello
    • English
    Cholinergic Involvement in Neurodegenerative Diseases, Volume 211 reviews cholinergic function in the brain as it relates to Neurodegenerative disorders. Coverage includes Alzheimer’s, dementia, Down Syndrome, Parkinson’s, Huntington’s, ALS, and more. In addition, the anatomy of the cholinergic system is described as well as the distribution and function of receptors.

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