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Books in Life sciences

  • Ocular Transporters and Receptors

    Their Role in Drug Delivery
    • 1st Edition
    • Ashim K Mitra
    • English
    Ocular transporters and receptors contains detailed descriptions of major transporters and receptors expressed in the eye, with special emphasis on their role in drug delivery. The complex anatomy and the existence of multiple barriers in the eye pose a considerable challenge to successful drug delivery to the eye. Hence ocular transporters and receptors are important targets for drug delivery. A significant advancement has been made in the field of ocular transport research and their role in drug delivery. In this book the cutting edge research being carried out in this field is compiled and summarized. The book focuses on key areas, including the anatomy and physiology of the eye, biology of ocular transporters and receptors, techniques in characterization of transporters and receptors, transporters and receptors in the anterior and posterior segment in the eye, the role of ocular transporters and receptors in drug delivery, and transporter-metaboli... interplay in the eye.
  • Orphan Drugs

    Understanding the Rare Disease Market and its Dynamics
    • 1st Edition
    • Elizabeth Hernberg-Ståhl + 1 more
    • English
    This authoritative and comprehensive book makes the reader familiar with the processes of bringing orphan drugs to the global market. There are between 5,000 and 7,000 rare diseases and the number of patients suffering from them is estimated to be more than 50 million in the US and Europe. Before the orphan drug legislation enacted in the US in 1983, there was a limited interest from industry to develop treatment for very small patient groups. One of the difficulties is, of course, that similar levels of investment are needed from a pharmaceutical company to bring a drug to the market for both small and large patient groups.The journey from application of an orphan drug designation to a reimbursed market- approved drug is long and many obstacles occur during the journey.After reading the book, readers will: Understand who the players/stakeholders are in the rare orphan disease field and their specific needs and concerns: patients and patient organizations, researchers and treating physicians within the field, industry, regulatory and reimbursement bodies* Understand the strong partnership between the different players and the various initiatives to improve and increase access to treatment for patients; minimizing the gap between numbers of known diseases, orphan designations, approved drugs and paid drugs.The book also provides short practical case stories from patients and researchers, as well as representatives from industry and authorities on the challenges they came across in developing orphan drugs or getting access to orphan drugs.
  • The Funding of Biopharmaceutical Research and Development

    • 1st Edition
    • David R Williams
    • English
    The funding of biopharmaceutical research and development provides a comprehensive critical review of the funding of research and development (R&D) in the human biopharmaceutical market sector. It addresses both private and public funding sources available in the US and internationally. The biopharmaceutical market is among the most research-intensive market sectors globally. Clinical researchers face a multitude of public and private funding options with respect to bringing their idea or innovation to market. These funding options are continually changing and complex, and are expected to decrease in the near future. A lack of understanding of the scale, scope, and inner workings of the funding aspects of R&D can, at times, act as a barrier for all involved, and can slow down or even eliminate the R&D process. The book lessens these barriers by describing the theoretical underpinnings, present practice, and trends in R&D funding in this market sector, both in the US and internationally. This includes a review and discussion of public-private partnership activity and their inner-workings, noting the complementary relationship between public and private funding. The book also contains an overview of the inner-workings of strategic alliance activity, including the advantages and disadvantages for each party. It goes on to provide an outline of venture capital activity, detailing the methods by which venture capital firms raise capital and are organized, a description of the venture capital-entrepreneur arrangement, and the effects of this arrangement. The book also presents an overview of the IPO process and the various fates of firms going public.
  • Food Microstructures

    Microscopy, Measurement and Modelling
    • 1st Edition
    • Vic Morris + 1 more
    • English
    The development of high-quality foods with desirable properties for both consumers and the food industry requires a comprehensive understanding of food systems and the control and rational design of food microstructures. Food microstructures reviews best practice and new developments in the determination of food microstructure.After a general introduction, chapters in part one review the principles and applications of various spectroscopy, tomography and microscopy techniques for revealing food microstructure, including nuclear magnetic resonance (NMR) methods, environmental scanning electron, probe, photonic force, acoustic, light, confocal and infrared microscopies. Part two explores the measurement, analysis and modelling of food microstructures. Chapters focus on rheology, tribology and methods for modelling and simulating the molecular, cellular and granular microstructure of foods, and for developing relationships between microstructure and mechanical and rheological properties of food structures. The book concludes with a useful case study on electron microscopy.Written by leading professionals and academics in the field, Food microstructures is an essential reference work for researchers and professionals in the processed foods and nutraceutical industries concerned with complex structures, the delivery and controlled release of nutrients, and the generation of improved foods. The book will also be of value to academics working in food science and the emerging field of soft matter.
  • Microfluidic Devices for Biomedical Applications

    • 1st Edition
    • Xiujun (James) Li + 1 more
    • English
    Microfluidics or lab-on-a-chip (LOC) is an important technology suitable for numerous applications from drug delivery to tissue engineering. Microfluidic devices for biomedical applications discusses the fundamentals of microfluidics and explores in detail a wide range of medical applications.The first part of the book reviews the fundamentals of microfluidic technologies for biomedical applications with chapters focussing on the materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies. Chapters in part two examine applications in drug discovery and controlled-delivery including micro needles. Part three considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering. The final part of the book covers the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis.Microfluid... devices for biomedical applications is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries.
  • Metabolomics in Food and Nutrition

    • 1st Edition
    • Bart C Weimer + 1 more
    • English
    Metabolomics enables valuable information about the biochemical composition of foods to be rapidly obtained. Since the biochemical profile of food largely determines key food properties such as flavour and shelf life, the information gained using metabolomics-based methods will enable greater control of food quality and also help to determine the relationship between diet and health. Metabolomics in food and nutrition provides an overview of their current and potential use in the food industry.Part one reviews equipment, methods and data interpretation in metabolomics including the use of nuclear magnetic resonance (NMR), statistical methods in metabolomics, and metabolic reconstruction databases and their application to metabolomics research. Part two explores applications of metabolomics in humans, plants and food. Chapters discuss metabolomics in nutrition, human samples for health assessments, and current methods for the analysis of human milk oligosaccharides (HMOs) and their novel applications. Further chapters highlight metabolomic analysis of plants and crops, metabolomics for the safety assessment of genetically modified (GM) crops, and applications of metabolomics in food science including food composition and quality, sensory and nutritional attributes.With its distinguished editors and team of expert contributors, Metabolomics in food and nutrition is a technical resource for industrial researchers in the food and nutrition sectors interested in the potential of metabolomics methods and academics and postgraduate students working in the area.
  • Improving the Safety and Quality of Nuts

    • 1st Edition
    • Linda J Harris
    • English
    As tree nuts and peanuts become increasingly recognised for their health-promoting properties, the provision of safe, high quality nuts is a growing concern. Improving the safety and quality of nuts reviews key aspects of nut safety and quality management.Part one explores production and processing practices and their influence on nut contaminants. Chapters discuss agricultural practices to reduce microbial contamination of nuts, pest control in postharvest nuts, and the impact of nut postharvest handling, de-shelling, drying and storage on quality. Further chapters review the validation of processes for reducing the microbial load on nuts and integrating Hazard Analysis Critical Control Point (HACCP) and Statistical Process Control (SPC) for safer nut processing. Chapters in part two focus on improving nut quality and safety and highlight oxidative rancidity in nuts, the impact of roasting on nut quality, and advances in automated nut sorting. Final chapters explore the safety and quality of a variety of nuts including almonds, macadamia nuts, pecans, peanuts, pistachios and walnuts.Improving the safety and quality of nuts is a comprehensive resource for food safety, product development and QA professionals using nuts in foods, those involved in nut growing, nut handling and nut processing, and researchers in food science and horticulture departments interested in the area.
  • Biotextiles as Medical Implants

    • 1st Edition
    • M W King + 2 more
    • English
    Textiles play a vital role in the manufacture of various medical devices, including the replacement of diseased, injured or non-functioning organs within the body. Biotextiles as medical implants provides an invaluable single source of information on the main types of textile materials and products used for medical implants. The first part of the book focuses on polymers, fibers and textile technologies, and these chapters discuss the manufacture, sterilization, properties and types of biotextiles used for medical applications, including nanofibers, resorbable polymers and shaped biotextiles. The chapters in part two provide a comprehensive discussion of a range of different clinical applications of biotextiles, including surgical sutures, arterial prostheses, stent grafts, percutaneous heart valves and drug delivery systems.This book provides a concise review of the technologies, properties and types of biotextiles used as medical devices. In addition, it addresses the biological dimension of how to design devices for different clinical applications, providing an invaluable reference for biomedical engineers of medical textiles, quality control and risk assessment specialists, as well as managers of regulatory affairs. The subject matter will also be of interest to professionals within the healthcare system including surgeons, nurses, therapists, sourcing and purchasing agents, researchers and students in different disciplines.
  • Catalogue of the Cicadoidea (Hemiptera: Auchenorrhyncha)

    • 1st Edition
    • Allen F. Sanborn
    • English
    This is the third in a series of catalogs and bibliographies of the Cicadoidea covering 1981-2010. The work summarizes the cicada literature, providing a means for easy access to information previously published on a particular species or to allow researchers the ability to locate similar work that has been published on other species. A total of 2,591 references are included in the bibliography. The book is a source of biological and systematic information that could be used by zoologists, entomologists, individuals interested in crop protection, and students studying entomology as well as anyone interested in cicadas or who require specific information on the insects. Each genus/species is identified with the reference, the page number, any figures (if applicable), the topics covered by the reference, any synonymies, and any biogeographic information mentioned for the species in the individual reference. An added benefit to the catalog is that it is the first complete species list for the Cicadoidea, including all synonymies and new combinations through 2012.
  • Managing Burnout in the Workplace

    A Guide for Information Professionals
    • 1st Edition
    • Nancy McCormack + 1 more
    • English
    Information professionals are under constant stress. Libraries are ushering in sweeping changes that involve the closing of branches and reference desks, wholesale dumping of print, disappearing space, and employment of non-professional staff to fill what have traditionally been the roles of librarians. Increasing workloads, constant interruptions, ceaseless change, continual downsizing, budget cuts, repetitive work, and the pressures of public services have caused burnout in many information professionals.Managi... Burnout in the Workplace concentrates on the problem of burnout, what it is and how it differs from chronic stress, low morale, and depression. The book addresses burnout from psychological, legal, and human resources perspectives. Chapters also cover how burnout is defined, symptom recognition, managing and overcoming burnout, and how to avoid career derailment while coping with burnout.
  • Plant Virology

    • 5th Edition
    • Roger Hull
    • English
    The seminal text Plant Virology is now in its fifth edition. It has been 10 years since the publication of the fourth edition, during which there has been an explosion of conceptual and factual advances. The fifth edition of Plant Virology updates and revises many details of the previous edition while retaining the important earlier results that constitute the field's conceptual foundation. Revamped art, along with fully updated references and increased focus on molecular biology, transgenic resistance, aphid transmission, and new, cutting-edge topics, bring the volume up to date and maintain its value as an essential reference for researchers and students in the field.
  • Transporters in Drug Discovery and Development

    Detailed Concepts and Best Practice
    • 1st Edition
    • Yurong Lai
    • English
    Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide to drug transporter families that are the most important for drug discovery and development. It covers: an overview of transporter families and organ distribution; clinical relevant drug-drug interaction; clinical relevant polymorphism; drug transporter related pharmacokinetic, pharmacodynamics and toxicity; in vitro/in vivo probes of drug transport studies; the practical methodologies of industrial transporter screening and translational aspect in drug discovery and developments.
  • Research Methods in Biomineralization Science

    • 1st Edition
    • Volume 532
    • English
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in biomineralization science, and includes sections on such topics as determining solution chemistry, structure and nucleation; probing structure and dynamics at surfaces; and interfaces mapping biomineral and morphology and ultrastructure.
  • Biological DNA Sensor

    The Impact of Nucleic Acids on Diseases and Vaccinology
    • 1st Edition
    • Ken Ishii + 1 more
    • English
    Biological DNA Sensor defines the meaning of DNA sensing pathways and demonstrates the importance of the innate immune responses induced by double stranded DNA (dsDNA) through its influencing functions in disease pathology and immune activity of adjuvants for vaccines. Though discussed in specific subsections of existing books, dsDNA and its immunogenic properties has never received the complete treatment given in this book. Biological DNA Sensor approaches the impact of dsDNA's immunogenicity on disease and vaccinology holistically. It paints a complete and concise picture on the topic so you can understand this area of study and make more informed choices for your respective research needs. Chapters are authored by researchers who are renowned for their research focus, ensuring that this book provides the most complete views on the topics.
  • Laboratory Methods in Enzymology: Cell, Lipid and Carbohydrate

    • 1st Edition
    • Volume 533
    • English
    Methods in Enzymology volumes provide an indispensable tool for the researcher. Each volume is carefully written and edited by experts to contain state-of-the-art reviews and step-by-step protocols. In this volume, we have brought together a number of core protocols concentrating on Cell, Lipid and Carbohydrate, complementing the traditional content that is found in past, present and future Methods in Enzymology volumes.
  • Diabetes

    Oxidative Stress and Dietary Antioxidants
    • 1st Edition
    • Victor R. Preedy
    • English
    Diabetes: Oxidative Stress and Dietary Antioxidants bridges the trans-disciplinary divide among diabetologists, endocrinologists, and nutritionists in understanding and treating diabetes. The book covers, in a single volume, the science of oxidative stress in diabetes and the potentially therapeutic use of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes such as apoptosis, cell signaling, receptor-mediated responses and more. This approach recognizes that diseases are usually multifactorial and that oxidative stress is a single component of this.Pharmacological treatments for diabetes are commonly marked by unwanted side effects, leading to treatment efforts using naturally occurring substances. But a plant-based approach alone is not sufficient; understanding the processes inherent in the oxidative stress of diabetes is vital for clinical workers, dietitians, and nutritionists.This translational work provides that understanding. The book begins by covering the basic biology of oxidative stress from molecular biology to imaging in relation to diabetes. There are chapters on neuropathy, nephropathy, atherosclerosis, cardiomyopathy, and retinopathy. The book then moves on to antioxidants in foods, including plants, components of the diet, and their relevance to diabetes.
  • Advances in Marine Biology

    • 1st Edition
    • Volume 66
    • English
    Advances in Marine Biology has been providing in-depth and up-to-date reviews on all aspects of marine biology since 1963--over 40 years of outstanding coverage! The series is well known for its excellent reviews and editing. Now edited by Michael Lesser (University of New Hampshire, USA) with an internationally renowned Editorial Board, the serial publishes in-depth and up-to-date content on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology, and biological oceanography.
  • Neuroanatomy of Language Regions of the Human Brain

    • 1st Edition
    • Michael Petrides
    • English
    Many studies of the neural bases of language processes are now conducted with functional and structural neuroimaging. Research is often compromised because of difficulties in identifying the core structures in the face of the complex morphology of these regions of the brain. Although there are many books on the cognitive aspects of language and also on neurolinguistics and aphasiology, Neuroanatomy of Language Regions of the Human Brain is the first anatomical atlas that focuses on the core regions of the cerebral cortex involved in language processing. This atlas is a richly illustrated guide for scientists interested in the gross morphology of the sulci and gyri of the core language regions, in the cytoarchitecture of the relevant cortical areas, and in the connectivity of these areas. Data from diffusion MRI and resting-state connectivity are integrated iwth critical experimental anatomical data about homologous areas in the macaque monkey to provide the latest information on the connectivity of the language-relevant cortical areas of the brain. Although the anatomical connectivity data from studies on the macaque monkey provide the most detailed information, they are often neglected because of difficulties in interpreting the terminology used and in making the monkey-to-human comparison. This atlas helps investigators interpret this important source of information. Neuroanatomy of Language Regions of the Human Brain will assist investigators of the neural bases of language in increasing the anatomical sophistication of their research adn in evaluating studies of language and the brain.
  • Polyphenols in Human Health and Disease

    • 1st Edition
    • Ronald Ross Watson + 2 more
    • English
    Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more.
  • Platelets and Aspirin-Induced Asthma

    Pathogenesis and Melatonin
    • 1st Edition
    • Helen Evsyukova
    • English
    Platelets and Aspirin-Induced Asthma is the first book to be published that reflects research conducted on aspirin-induced asthma pathogenesis. It is examined through positions of neuroimmunoendocrine interactions in organism. The Melatonin hormone plays a key role, being the regulator and coordinator of complicated and interrelated biological processes. This new concept of aspirin-induced asthma pathogenesis suggests new methods for treatment of this disease by means of correcting the melatonin content in the patient’s organism. Investigations into the mechanisms of aspirin-induced asthma as a pathology of melatonin producing cells of platelets helps to determine high-risk groups and develop preventive measures and adequate therapy.
  • Physiology of Metabolism

    • 1st Edition
    • David D. Davies
    • English
    The Biochemistry of Plants, Volume 12: Physiology of Metabolism focuses on plant biochemistry, with emphasis on the metabolism of plants. This book discusses the organizational resistance to account for changes in the rate of respiration that both cells and organs undertake. Organized into two parts encompassing eight chapters, this volume starts with an overview of the microtubule structure and function in plant cell biology. This book then discusses the presence of microtubular structures in the cytoplasm of eukaryotic cells. Other chapters consider the characteristics of plant cells, which possess the highest degree of subcellular compartmentation of metabolism. This text discusses as well the various transport reactions that are involved in primary metabolic pathways in plants. The final chapter explores the several changes that fruits undergo to reach maturity, including the development of color and aroma, as well as improvements in texture and flavor. This book is a valuable resource for biologists, plant scientists, and agriculturists.
  • The Physiology of Growth

    • 1st Edition
    • I.C. Gunsalus
    • English
    The Bacteria, Volume IV: The Physiology of Growth focuses on the biochemical phenomena that are expressed at the level of the intact microbial cell and of the growing cell. This book explores the structure, metabolism, and biosynthesis of bacteria. Organized into nine chapters, this volume starts with an overview of the growth requirements, metabolic pathways, individual enzymes, and a variety of other components and functions of the bacterial cell. This text then analyzes the genetic organization of bacteria and explains the nuclear division in bacteria. Other chapters consider the effects of physical environment upon the growth of microorganisms. This book discusses as well the methods for obtaining bacterial cultures by manipulating environmental factors. The final chapter deals with chemotherapeutic drugs, which are valuable tools in the investigation of bacterial organization and function. Bacteriologists, microbiologists, biochemists, microbial physiologists, and cell physiologists interested in the study of bacteria will find this book extremely useful.
  • The Rat Brain in Stereotaxic Coordinates

    • 7th Edition
    • George Paxinos + 1 more
    • English
    Since its first edition in 1982, the Paxinos and Watson rat brain atlas has become the most trusted source of accurate coordinates and anatomical information in laboratories throughout the world. It has been cited over 60,000 times, making it the most cited publication in neuroscience. The seventh edition incorporates new findings on developmental gene expression and presents the boundaries of neuromeres in sagittal sections.
  • Techniques in Protein Chemistry

    • 1st Edition
    • Choh Hao Li
    • English
    Hormonal Proteins and Peptides: Techniques in Protein Chemistry, Volume IX presents the various methods in protein chemistry and discusses their use for hormonal protein investigations. This book examines the approach to investigating biologically active peptides, which is based on a combination of chromatographic and fluorometric procedures. Organized into five chapters, this volume starts with an overview of the fluorometric methods for analysis of peptides and proteins with focus on their use in high performance liquid chromatography. This text then presents a thorough discussion on partition chromatography of proteins and peptides. Other chapters consider a comprehensive account of absorption and fluorescence techniques for the structural analysis of proteins. This book presents as well a comprehensive discussion on optical rotatory dispersion and circular dichroism methods and their application for the study of protein conformation. The final chapter deals with the historical aspects of fetuin and ultracentrifuge. This book is a valuable resource for chemists, biologists, endocrinologists, and physicians.
  • The Peripheral Blood Film

    • 2nd Edition
    • Trevor A. Harper
    • English
    The Peripheral Blood Film, Second Edition presents the various concepts of the origin, development, and functions of blood cells. This book serves as a practical guide to the different types of film appearances that may be encountered in the routine examination of peripheral blood films. Organized into 14 chapters, this edition begins with an overview of the composition of plasma, which consists mainly of water and many organic and inorganic compounds. This text then discusses the process of obtaining capillary blood and explains how the thin blood film is prepared in the laboratory. Other chapters present the alphabetical listing of diseases, disorders, and abnormal film appearances for easier reference. This book discusses as well the characteristics of normal peripheral blood cells. The final chapter deals with the characteristics of blood film in various types of diseases, including Cushing's disease, Addison's disease, cirrhosis of the liver, and collagen disorders. This book is a valuable resource for hematologists and pathologists.
  • Basic Soil Mechanics

    • 1st Edition
    • G W E Milligan + 1 more
    • English
  • Physiology and Toxicology of Male Reproduction

    • 1st Edition
    • James C. Lamb + 1 more
    • English
    Physiology and Toxicology of Male Reproduction is a collection of papers that deals with general reproductive biology and specific aspects of reproductive toxicology, pertaining to the male sex. Some papers discuss testicular organization, reproductive toxicity testing systems, and germ-cell genetic toxicology. The use of in vitro systems by investigators to dissect the male reproductive toxicants can lead to a more scientific approach toward hazard assessment and the development of safer drugs and chemicals. Other papers explain the fundamental reproductive biology of the testis, the neuroendocrine system, the epididymis and accessory sex organs, and spermatozoal evaluation. Toxicological aspects cover the toxicological evaluation of the complete reproductive system, testicular morphology, sperm assessment, and germ-cell mutagenesis. One paper describes alternative methods in toxicology—by using new in vitro systems that should reduce or eliminate the need for tests conducted on animals. In vitro methodology embraces other systems such as from subcellular fractions to isolated intact organs. In relation to target-organ toxicity, the researcher can focus using primary cell cultures. This collection will prove helpful to toxicologists, graduate students and researchers in biology, particularly in male reproductive toxicology and fertility testing.
  • The Saccharine Disease

    Conditions Caused by the Taking of Refined Carbohydrates, Such as Sugar and White Flour
    • 1st Edition
    • T. L. Cleave
    • English
    The Saccharine Disease, Conditions Caused by the Taking of Refined Carbohydrates, such as Sugar and White Flour contends that the causation of these conditions has been obscured through confusing distinctions between unnatural, refined carbohydrates and that of natural, unrefined carbohydrates like fruits and whole meal flour. The author notes that all the foregoing conditions are really the manifestations of a single master-disease—that many of the major diseases of modern societies are caused by consuming unreasonable amounts of refined carbohydrate foods. The author discusses that in the short time that man has changed his diet, evolutionary adaptation is left behind. He gives two rules to prevent and arrest all saccharine disease manifestations: Do not eat any food unless you definitely want it, and avoid eating white flour or white sugar. These two rules will prevent gastric or duodenal ulcer, diabetes, coronary disease, constipation, complications of varicose veins, hemorrhoids, E. coli infections, obesity, and some skin conditions, As a retired Surgeon-General of the Royal Navy, the author bases his assumptions on evolutionary, epidemiological, and other scientific or historical work. This book can give insights to dieticians, food researchers, nutritionists, people on diet, and general medicine practioners.
  • Mycobacteria

    Institute of Medical Laboratory Sciences Monographs
    • 1st Edition
    • Maureen V. Chadwick
    • F. J. Baker
    • English
    Mycobacteria covers some aspects of mycobacterial identification. The book starts by describing a historical review of tuberculosis, including topics about searching for its causes and cure and about the use of chemotherapy for treating tuberculosis. The text describes the different species of Mycobacteriaceae, including Mycobacterium tuberculosis, M. africanum, M. bovis, M. microti, and M. ulcerans. Safety precautions in pathology laboratories; the preparation of good culture media and sensitivity test media; and the treatment of specimens are also considered. The book further tackles sensitivity testing of Mycobacteria using the resistance ratio method, the proportional method and the absolute concentration method, and methods of identifying mycobacteria. The text also describes assay methods for anti-tuberculosis drugs. Pathologists, medical technologists, and other people working in pathology laboratories will find the book useful.
  • Food Legislative System of the UK

    • 1st Edition
    • Stephen J. Fallows
    • English
    Food Legislative System of the UK discusses the principles underlying the country's food laws, the historical context of today's food legislation, and the process for amendments in legislation. The book also reviews the influences on the system such as those arising from interest groups, the changing diet, and health environment. In addressing the Food Legislative System of the United Kingdom, the book tackles various examples of food legislation and numerous food- related advisory bodies. Industry, consumer, or enforcement pressures can initiate changes and modifications of laws. Once ministers are convinced that a prima-facie case exists for amending food legislation, they will seek advice from various authorities; make a draft, and present it for full parliamentary procedure. For example, the "Food and Environment Bill" has passed through Parliament by ministers representing the Ministry of Agriculture, Fisheries and Food, while the "Food Bill" has gone through another route with the chief legal officers and company. The book emphasizes the mechanisms through which change is achieved, as well as the points when opportunities exist for interest groups to make their views known to the decision makers. The book can be helpful for food lobbyists, consumer food groups, nutritionists, political scientists, and heads of food and welfare organizations.
  • Recent Developments in Ruminant Nutrition

    • 1st Edition
    • W Haresign + 1 more
    • English
    Recent Developments in Ruminant Nutrition presents papers that discuss the advancement of the different areas of ruminant nutrition. The book is comprised of 20 chapters that cover topics, such as reproduction, diet, and nutrition. The coverage of the text includes growth stimulation in ruminants; protein quantity and quality for the U.K. dairy cow; and complete-diet feeding of dairy cows. The book also covers rumen fermentation related topics, such as influence of nitrogen and carbohydrate inputs on rumen fermentation; aspects of the biochemistry of rumen fermentation and their implication in ruminant productivity; and manipulation of rumen fermentation. The text will be of great use to researchers and professionals in the animal husbandry industry.
  • Recent Developments in Pig Nutrition

    • 1st Edition
    • D J A Cole + 1 more
    • English
    Recent Developments in Pig Nutrition shows the updates in the nutrition and the evaluation of energy needs in raising and breeding pigs. The book covers the energy requirement of pigs; the effects of climatic variables on the nutrition and energy of pigs; and the prediction of energy content in pig feeds. The availability and importance of proteins and amino acids in pig feeds are also discussed. The text also explains the importance of vitamins and minerals in the diet of pigs; the nutritional needs of the different sexes of pigs and piglets; and the processing and evaluation of cereals for pig diets. The monograph is recommended for those in piggery business, who want to know more about the importance of pig nutrition and be updated with the different findings in the field. The book will also be good for animal nutritionists who concern themselves with pig feeds and for veterinarians who specialize in pigs.
  • Plant Pests and their Control

    • 1st Edition
    • Peter G. Fenemore
    • English
    Plant Pests and their Control, Revised Edition discusses the concepts involved in pest management, along with its application, constraints, and opportunities. This book is comprised of 13 chapters that cover topics relevant in understanding the basis and practice of pest management. The first six chapters deal with the various aspects of entomology. These chapters cover the importance of insects; the physiological properties of insects; and reproduction and life cycle. The next chapter covers the non-insect pests. Chapter 8 discusses the relationship between insects and plants, while Chapter 9 covers the mortality factors of insect, such as predators, parasites, and pathogens. The next chapter presents the ecological background of pest control. The remaining three chapters discuss pest management itself. This text will be of great use to agriculturists, horticulturalists, and pest control professionals. Household owners dealing with residential pest infestation will also find this book a great source of information.
  • Elements of Marine Ecology

    An Introductory Course
    • 3rd Edition
    • R. V. Tait
    • English
    Elements of Marine Ecology: An Introductory Course, Third Edition provides a concise discussion on the general field of marine ecology. The book is comprised of nine chapters that cover the structures and functions of marine ecosystems. The text first covers the oceans, including its extent and depths, currents, and biological features. Chapter 2 deals with marine planktons. Next, the book discusses the measuring and sampling techniques used at sea to obtain information of interest. The fourth chapter tackles the parameters of marine environment, while the fifth chapter deals with organic production in the sea. The text also covers the two extremities of the sea that are the seashore and the sea bottom. The last chapter discusses some concerns in sea fisheries. The book will be of great use to researchers and professionals whose work involves marine flora and fauna.
  • Forensic Toxicology

    Proceedings of a Symposium Held at the Chemical Defence Establishment, Porton Down, 29-30 June 1972
    • 1st Edition
    • Bryan Ballantyne
    • English
    Forensic Toxicology presents the legal and medical aspects of the detrimental effects of chemicals on humans. This book discusses the immediate and long-term consequences of accident or deliberate poisoning, the detection of such poisoning, and the interpretation of the possible importance of demonstrating exogenous substances in biological fluids and tissues. Organized into 14 chapters, this compilation of papers begins with an overview of the fundamental procedure and interpretation in forensic toxicology. This text then examines the ways in which enzymes may be used in the analysis of drugs. Other chapters consider the equipment and reagents required in the rapid tests for drugs in urine. This book presents as well barbiturate poisoning from the viewpoint of the forensic pathologist performing the post mortem over the cause of death. The final chapter deals with further advances in forensic toxicology. This book is a valuable resource for general practitioners, forensic toxicologists, forensic pathologists, and police officers.
  • Recent Developments in Poultry Nutrition

    • 1st Edition
    • D.J.A. Cole + 1 more
    • English
    Recent Developments in Poultry Nutrition is a collection of studies that cover important developments in poultry nutrition. The book presents 23 papers that deal with the various areas of concerns in poultry nutrition. The coverage of the text includes materials that deal with poultry diet, such as metabolizable energy evaluation of poultry diets; the impact of declaration of the metabolizable energy value of poultry feeds; and the influence of fiber on digestibility of poultry feeds. The book also deals with egg production issues, including the influence of nutritional factors on hatchability; eggshell formation and quality; and dietary phosphorus for laying hens. The text will be of great use to researchers and professionals in the poultry industry. Consumers will also find this book interesting since it discusses topics that can directly affect them.
  • Routes of Drug Administration

    Topics in Pharmacy
    • 1st Edition
    • A. T. Florence + 1 more
    • English
    Routes of Drug Administration covers topics about parenteral and enteral routes of drug administration. The book discusses the anatomy and physiology of administration sites; the formulation and design of delivery systems; and other relevant aspects of biopharmaceutics. The text describes pulmonary delivery, nasal, buccal, and transdermal routes of administration for systemic delivery, as well as a number of systems for more localized therapy with antibiotics. Innovative methods of antibiotic administration, such as continuous and intermittent infusion, endotracheal installation, aerosol delivery, antibiotic-impregnat... catheters, antibiotic-containin... bone cement, and beads, are also considered. Senior undergraduate and postgraduate students in pharmacy, medicine, nursing and allied health sciences and practitioners in these fields, as well as other professionals concerned with the preparation and administration of medicines and the monitoring of drug therapy will find the book useful.
  • Theory and Practice of Blood Flow Measurement

    • 1st Edition
    • John P. Woodcock
    • English
    Theory and Practice of Blood Flow Measurement presents the methods for determining the metrics of blood flow in the major vessels. This book is organized into two sections encompassing 16 chapters that discuss the theories behind the different techniques of flow measurement and the performance of flowmeters and their practical application to determining blood flow volume in the tissues and organs. Considerable chapters are devoted to various methods of blood measurement, including dilution, transport, and thermal techniques, as well as the effect of catheter sampling on the shape of indicator dilution curves. Other chapters are concerned with the possible errors in the application of indicator dilution techniques and the types of dilution indicator, and measurement of indicator concentration. A chapter is devoted to the advantages and disadvantages of thermistor flowmeter. The last chapter focuses on the design of a thermal dilution catheter. The book can provide useful information to physicists, bioengineers, surgeons, students, and researchers.
  • A Synopsis of Infectious and Tropical Diseases

    • 3rd Edition
    • A. W. Woodruff + 1 more
    • English
    A Synopsis of Infectious and Tropical Diseases provides a summary of information on the diagnosis and management of infectious and tropical diseases. It contains essential information required by general practitioners, specialists, medical students and graduates preparing for higher examinations, the nursing profession, and health workers in the proper management of infective and tropical diseases. This book is organized into nine chapters that describe the signs and symptoms, clinical forms and manifestations, incubation period, stages of invasion, mode of transmission, epidemiology, and treatment of different tropical and infectious diseases such as those caused by viruses, protozoans, and metazoan parasites. These diseases include herpesvirus infections, blackwater fever, and trematode or fluke infections. This book will be of interest to travelers and people in the medical profession.
  • Recent Developments in Ruminant Nutrition – 2

    • 1st Edition
    • W. Haresign + 1 more
    • English
    Recent Developments in Ruminant Nutrition – 2 presents papers that discuss the advances in the different areas of ruminant nutrition. The book is comprised of 22 chapters that discuss topics such as milk production, health, and nutrition. The coverage of the text includes meeting the nutrient requirements of beef cattle in forage-based systems of production; nutrient requirements of intensively reared beef cattle; and feeding for high margins in dairy cows. The book also tackles issues concerning milk production such as photoperiodic influences on milk production in dairy cows; manipulation of milk yield with growth hormone; and the influence of level and pattern of concentrate input on milk output. The text will be of great use to researchers and professionals in the animal husbandry industry.
  • Annual European Symposium on Photomorphogenesis

    Photochemistry and Photobiology
    • 1st Edition
    • Pill-Soon Song
    • English
    Annual European Symposium on Photomorphogenesis, Volume 27: Photochemistry and Photobiology covers the proceedings of the 1977 Annual European Symposium on Photomorphogenesis, held in Bet Dagan, Israel. This book is divided into 25 chapters and begins with an examination of different forms of phytochrome in extracts of etiolated oat seedlings. The succeeding chapters review the involvement and interaction of membranes, hormones, and the circadian clock. These chapters also look into the effects of light on oscillations of enzyme activity in extracts and the differential effects of calcium on Mougeotia chloroplast movement. These topics are followed by discussions of in vitro transcription and translation of light; the concept of plastid photomorphogenesis; and the photocontrol of plant growth. The final chapters explore the blue light effects on lower and higher plants and the photomorphogenesis in microorganisms, algae, and mosses. This book will be of great value to photochemists, photobiologists, and researchers.
  • Presynaptic Receptors and Neuronal Transporters

    Official Satellite Symposium to the IUPHAR 1990 Congress Held in Rouen, France, on 26–29 June 1990
    • 1st Edition
    • S.Z. Langer + 2 more
    • English
    Advances in the Biosciences, Volume 82: Presynaptic Receptors and Neuronal Transporters documents the proceedings of the Official Satellite Symposium to the IUPHAR 1990 Congress held in Rouen, France on June 26-29, 1990. The first part of this book deals with the extensive and still increasing list of presynaptic release-modulating auto and heteroreceptors, emphasizing the various subtypes of presynaptic receptors that are characterized by functional studies, both in vitro and in vivo, using a number of experimental approaches. The next chapters are devoted to the molecular pharmacology of presynaptic receptors, of which can interfere with G proteins and modify the activity of adenylate cyclase, guanylate cyclase, or protein kinase C. The purification and molecular biology of transporter systems, including cloning and sequencing of the neuronal sodium-ion coupled GABA transporter are also discussed. This compilation concludes with insights on the function of presynaptic receptors and neuronal transporters both in the periphery and in the CNS, as well as their ubiquitous locations and physiological roles. This publication is a good reference for students and individuals researching on the presynaptic autoreceptors and neurotransmitters.
  • General Botany

    • 1st Edition
    • Wilhelm Nultsch
    • English
    General Botany covers certain aspects of general botany, such as morphology, anatomy, and histology. The book discusses the molecular constitution of plants; the structural constitution of the protoplasm, the cell, and the cytoplasm; and the differentiation of the cell. The text also describes the types of organization in plants; the internal and external structure of the stem, the leaf, and the root; and water and salt balance, with regard to the translocation of materials. The energy procurement and the synthetic processes in autotrophic plants; the respiration and energy transformations; and nitrogen metabolism are also considered. The book further tackles heterotrophy; reproduction; heredity; development; and the movement of plants. Botanists, cytologists, plant physiologists, and students taking related courses will find the text invaluable.
  • Principles of Horticulture

    • 2nd Edition
    • C.R. Adams + 2 more
    • English
    Principles of Horticulture, Second Edition covers the various topics concerning plant cultivation for agricultural use. The book is comprised of 17 chapters that tackle the various areas of concerns in horticulture. The coverage of the text includes the nurturing aspects of horticulture, including growth and development, genetics and breeding, and nutrition. The book also covers the various threats and problems encountered by horticulturists, such as pests, weeds, and harmful microorganisms. The text will be of great use to researchers and practitioners of plant-related fields, such as botany, agriculture, and particularly horticulture.
  • Essays in Toxicology

    Volume 1
    • 1st Edition
    • Frank R. Blood
    • English
    Essays in Toxicology, Volume 1 covers essays in toxicology and related topics. The book presents essays on the use of poisons as tools in studying the nervous system as well as teratology. The text also includes essays on the significance of methemoglobinemia in toxicology and lead poisoning. Biochemists, plant and animal physiologists, pharmacologists, pathologists, microbiologists, entomologists, food technologist, and people involved in forensic medicine and industrial medicine.
  • Experimental Analysis of Behavior

    • 1st Edition
    • Volume 6
    • I.H. Iversen + 1 more
    • English
    This volume is dedicated to the late B.F. Skinner as a tribute to his pioneering work on the Experimental Analysis of Behavior. This science that he initiated studies the behavior of individual organisms under laboratory conditions.The volume describes a broad collection of representative and effective research techniques in the Experimental Analysis of Behavior; techniques derived solely from infrahuman subjects, which have been selected both for their utility in behavior analysis and for their potential value in expanding the use of behavior analysis in the neurosciences. By bringing together under one cover the expertise of individual authors regarding techniques based on their particular laboratory experiences, the book provides an informative and practical source of methods and techniques for those practising or interested in Experimental Analysis of Behaviour.
  • Insect Molecular Genetics

    An Introduction to Principles and Applications
    • 1st Edition
    • Marjorie A. Hoy
    • English
    Developed as an introduction to new molecular genetic techniques, Insect Molecular Genetics also provides literature, terminology, and additional sources of information to students, researchers, and professional entomologists.Althou... most molecular genetics studies have employed Drosophila, this book applies the same techniques to other insects, including pest insects of economic importance.As a text, as a reference, as a primer, and as a review of a vast and growing literature, Insect Molecular Genetics is a valuable addition to the libraries of entomologists, geneticists, and molecular biologists.
  • Case Presentations in Heart Disease

    • 2nd Edition
    • Alan Mackintosh
    • English
    Case Presentations in Heart Disease: Second Edition presents cases dealing with the diagnosis and treatment of patients with a heart related problem. This book addresses the need for a sample of real life cardiologic problems. Some of the topics covered in the book are the case of the 63-year-old brewery worker with severe pain between the shoulder blades; a case of a 54 years old woman with pain in her right loin; a case of a man applying for insurance; and a case of a married man who experienced loss of consciousness lasting 5 minutes. Other topics discussed include the causes of dissecting aortic aneurysm, the diagnosis made on the female with pain in her right loin, and the development of atrial myxomas. The acute phase of a myocardial infarction is presented. The concluding part is devoted to the analysis of a case of coughing symptom with no smoking history. The book can provide useful information to doctors, cardiologists, students, and researchers.
  • The Origins of Agriculture

    An Evolutionary Perspective
    • 1st Edition
    • David Rindos
    • English
    The Origins of Agriculture: An Evolutionary Perspective presents an alternative approach to understanding cultural variation and change. It aims to demonstrate that domestication and the origin of agricultural systems are best understood by attempting to explicate the evolutionary forces that affected that development of domesticates and agricultural systems. The book begins by discussing cultural change, the domestication of plants, and the origin of agricultural systems in the most general of terms. It considers Darwinism in some depth, concentrating on the relationship between natural selection and cultural change. Subsequent chapters examine the world of domestication and agriculture and present a series of concepts that may permit a more natural explanation for these processes. These include concepts such as incidental domestication, specialized domestication, and agricultural domestication. The final two chapters present models for the origin and spread of agricultural systems based upon Darwinian evolutionary theory.
  • Fruit and Vegetables

    • 1st Edition
    • R. B. Duckworth
    • English
    Fruit and Vegetables provides comprehensive information on fruits and vegetables, which are deemed to be an important part of diets in every part of the world. The book is intended to be a primary source of information for advanced food science students and readers interested in the deep appreciation and understanding of food. The text illustrates the wide range of background material on the study of fruits and vegetables. Subjects on the chemical constitution and structure of fruits and vegetables are covered in Part I, Concerning the Nature of Fruit and Vegetables. Part II deals with the utilization, production, processing and trade of fruits and vegetables. Food technologists, food scientists, chefs, nutritionists, students and those in the food industry will find this book a good reference material.