
Ocular Transporters and Receptors
Their Role in Drug Delivery
- 1st Edition - October 31, 2013
- Imprint: Woodhead Publishing
- Author: Ashim K Mitra
- Language: English
- Hardback ISBN:9 7 8 - 1 - 9 0 7 5 6 8 - 8 6 - 2
- eBook ISBN:9 7 8 - 1 - 9 0 8 8 1 8 - 3 1 - 7
Ocular transporters and receptors contains detailed descriptions of major transporters and receptors expressed in the eye, with special emphasis on their role in drug delivery. The… Read more

Purchase options

Institutional subscription on ScienceDirect
Request a sales quote- Highly focused on ocular transporters
- Most up-to-date research compilation
- Detailed description of role of transporters and receptors in ocular drug discovery and delivery
List of figures and tables
About the authors
Chapter 1: Eye: anatomy, physiology and barriers to drug delivery
Abstract:
1.1 Introduction
1.2 Anatomy and physiology of the eye
1.3 Barriers to ocular drug delivery
1.4 Conclusions
1.5 Acknowledgements
Chapter 2: Biology of ocular transporters: efflux and influx transporters in the eye
Abstract:
2.1 Introduction
2.2 SLC transporters
2.3 ABC transporters
2.4 Conclusions
Chapter 3: Characterization of ocular transporters
Abstract:
3.1 Introduction
3.2 Molecular and cellular characterization
3.3 Functional characterization of transporters
Chapter 4: Transporters and receptors in the anterior segment of the eye
Abstract:
4.1 Introduction
4.2 Transporters and receptors
4.3 Anterior chamber influx transporters
4.4 Anterior chamber efflux transporters
4.5 Anterior chamber receptors
4.6 Other miscellaneous anterior chamber receptors
4.7 Conclusions
Chapter 5: Transporters and receptors in the posterior segment of the eye
Abstract:
5.1 Introduction
5.2 Influx transporters in posterior segment of the eye
5.3 Receptors in posterior segment of the eye
5.4 ABC transporters
5.5 Conclusion
Chapter 6: Transporters in drug discovery and delivery: a new paradigm in ocular drug design
Abstract:
6.1 Introduction
6.2 Transporter-targeted drug delivery to the anterior segment
6.3 Transporter-targeted drug delivery to the posterior segment
6.4 Conclusion
Chapter 7: Transporter-metabolism interplay in the eye
Abstract:
7.1 Introduction
7.2 Metabolizing enzymes in ocular tissues
7.3 Impact of disease state on the expression of metabolizing enzymes
7.4 Efflux transporters and metabolism interplay
7.5 Potential impact of the efflux metabolism interplay in ocular bioavailability
7.6 Drug design and formulation strategies to overcome the efflux and metabolism interplay
7.7 Conclusion
Index
- Edition: 1
- Published: October 31, 2013
- No. of pages (Hardback): 276
- No. of pages (eBook): 276
- Imprint: Woodhead Publishing
- Language: English
- Hardback ISBN: 9781907568862
- eBook ISBN: 9781908818317
AM