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Elsevier

Books in Life sciences

  • Recent Advances in Microbial Oxygen-Binding Proteins

    • 1st Edition
    • Volume 67
    • English
    This latest volume in Advances in Microbial Physiology continues the long tradition of topical and important reviews in microbiology.

  • Atlas of Early Zebrafish Brain Development

    A Tool for Molecular Neurogenetics
    • 2nd Edition
    • Dr. Thomas Mueller + 1 more
    • English
    Atlas of Early Zebrafish Brain Development: A Tool for Molecular Neurogenetics, Second Edition, remains the only neuroanatomical expression atlas of important genetic and immunohistochemical markers of this vertebrate model system. It represents a key reference and interpretation matrix for analyzing expression domains of genes involved in Zebrafish brain development and neurogenesis, and serves as a continuing milestone in this research area. This updated volume provides in-situ hybridized and immunostained preparations of complete series of brain sections, revealing markers of the fundamental stages in the life history of neuronal cells in very high quality preparations and photographic plates. Specific additions to this edition include documentation on the distribution of neurons expressing GABA, dopamine and serotonin, material on the basal ganglia, hypothalamus, and the caudal, segmented part of the diencephalon, new theories on the early organization of the telencephalon and thalamus, and integration of a comparative perspective on the mid- and hindbrain.

  • Canned Citrus Processing

    Techniques, Equipment, and Food Safety
    • 1st Edition
    • Yang Shan
    • English
    Citrus is one of the most popular fruits around the world, and can be successfully cultivated in more than 140 countries. Producing 75% of citrus consumed in the global market, China has become the new “Kingdom of Canned Citrus”. Canned Citrus Processing: Techniques, Equipment, and Food Safety comprehensively presents the technical and development trends of the canned citrus industry. This book provides solutions to typical problems of canned citrus manufacturing and processing; presents an overview of the canned citrus industry, introduces canned citrus processing machinery and equipment, and discusses the processing quality, safety control, and related standards.

  • Functional Dietary Lipids

    Food Formulation, Consumer Issues and Innovation for Health
    • 1st Edition
    • Thomas A. B. Sanders
    • English
    Functional Dietary Lipids: Food Formulation, Consumer Issues and Innovation for Health discusses this important component of the human diet and the ways it plays an essential functional role in many foods. The book covers the functionality and nutritional benefits of dietary fat in food in terms of formulation, manufacturing, and innovation for health. After an introduction by the editor reviewing the role of fats in the human diet, the book discusses the chemistry of edible fats, manufacturing issues, including the replacement of trans-fatty acids in food, fat reformulation for calorie reduction, thermal stability of fats, and the flavor and functional texture and melting characteristics of fats in food. Subsequent chapters address the effect of dietary lipid intake on various health issues and the potential health benefits of bioactive compounds in dietary lipids, with final sections discussing issues that affect the consumer relationship with fat, such as regulation, marketing, and health claims.

  • Translational Immunology

    Mechanisms and Pharmacologic Approaches
    • 1st Edition
    • Seng-Lai Tan
    • English
    Translational Immunology: Mechanisms and Pharmacologic Approaches highlights and summarizes the most important advances in human immunology, clinical translations, new tools to analyze therapeutic targets, and new pharmacological approaches for autoimmunity, inflammatory disorders, and cancer. The book is an essential resource for those seeking to understand the potential translational applications of burgeoning studies in human immunology, helping readers make sense of the existing and emerging scientific advances. The book grounds fundamental science in the translational realm, providing insights from world renowned researchers at the top of their game in their respective fields, in both industry and academic settings. Readers will gain an understanding of the rationale and mechanisms underlying current and emerging pharmacologic approaches for interventional immunology, the gaps therein, and new ideas for better and safer therapeutic approaches, and physicians will glean information about pharmacological limitations in altering disease progression and complications. This reference on the translational realization of the burgeoning findings in immunology provides a go-to reference for experienced professional clinicians, researchers, industry scientists, and those seeking more information on the field.

  • Current and Emerging Technologies for the Diagnosis of Microbial Infections

    • 1st Edition
    • Volume 42
    • English
    Current and Emerging Technologies in Microbial Diagnostics, the latest volume in the Methods in Microbiology series, provides comprehensive, cutting-edge reviews of current and emerging technologies in the field of clinical microbiology. The book features a wide variety of state-of-the art methods and techniques for the diagnosis and management of microbial infections, with chapters authored by internationally renowned experts. This volume focuses on current techniques, such as MALDI-TOF mass spectroscopy and molecular diagnostics, along with newly emerging technologies such as host-based diagnostics and next generation sequencing.

  • Translating Regenerative Medicine to the Clinic

    • 1st Edition
    • Jeffrey Laurence + 2 more
    • English
    Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole. Volumes in the series include Translating Gene Therapy to the Clinic, Translating Regenerative Medicine to the Clinic, Translating MicroRNAs to the Clinic, Translating Biomarkers to the Clinic, and Translating Epigenetics to the Clinic.

  • Innovation and Future Trends in Food Manufacturing and Supply Chain Technologies

    • 1st Edition
    • Craig Leadley
    • English
    Innovation and Future Trends in Food Manufacturing and Supply Chain Technologies focuses on emerging and future trends in food manufacturing and supply chain technologies, examining the drivers of change and innovation in the food industry and the current and future ways of addressing issues such as energy reduction and rising costs in food manufacture. Part One looks at innovation in the food supply chain, while Part Two covers emerging technologies in food processing and packaging. Subsequent sections explore innovative food preservation technologies in themed chapters and sustainability and future research needs in food manufacturing.

  • Craniofacial Development

    • 1st Edition
    • Volume 115
    • English
    Craniofacial Development, the latest volume of Current Topics in Developmental Biology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in Craniofacial Development, and includes sections on such topics as microRNAs in craniofacial development and epigenetic regulation in craniofacial development.

  • Physiology of Elasmobranch Fishes: Structure and Interaction with Environment

    • 1st Edition
    • Volume 34A
    • Robert E. Shadwick + 2 more
    • English
    Fish Physiology: Physiology of Elasmobranch Fishes, Volume 34A is a useful reference for fish physiologists, biologists, ecologists, and conservation biologists. Following an increase in research on elasmobranchs due to the plight of sharks in today’s oceans, this volume compares elasmobranchs to other groups of fish, highlights areas of interest for future research, and offers perspective on future problems. Covering measurements and lab-and-field based studies of large pelagic sharks, this volume is a natural addition to the renowned Fish Physiology series.

  • Physiology of Elasmobranch Fishes: Internal Processes

    • 1st Edition
    • Volume 34B
    • Robert E. Shadwick + 2 more
    • English
    Fish Physiology: Physiology of Elasmobranch Fishes, Volume 34B is a useful reference for fish physiologists, biologists, ecologists, and conservation biologists. Following an increase in research on elasmobranchs due to the plight of sharks in today’s oceans, this volume compares elasmobranchs to other groups of fish, highlights areas of interest for future research, and offers perspective on future problems. Covering measurements and lab-and-field based studies of large pelagic sharks, this volume is a natural addition to the renowned Fish Physiology series.

  • Forensic Toxicology

    Principles and Concepts
    • 1st Edition
    • Nicholas T. Lappas + 1 more
    • English
    Forensic Toxicology: Principles and Concepts takes the reader back to the origins of forensic toxicology providing an overview of the largely unchanging principles of the discipline. The text focuses on the major tenets in forensic toxicology, including an introduction to the discipline, fundamentals of forensic toxicology analysis, types of interpretations based on analytical forensic toxicology results, and reporting from the laboratory to the courtroom. Forensic Toxicology also contains appendices covering the principles of pharmacokinetics and pharmacodynamics, immunology and immunological assays, toxicogenomics, and case studies.

  • Emerging Technologies for Promoting Food Security

    Overcoming the World Food Crisis
    • 1st Edition
    • Chandra Madramootoo
    • English
    Emerging Technologies for Promoting Food Security: Overcoming the World Food Crisis discusses rising energy prices, increased biofuel use, water scarcity, and the rising world population, all factors that directly affect worldwide food security. The book examines the range of approaches to promoting global food security, including novel and existing agricultural and husbandry techniques for safe and sustainable food production. It is divided into three parts beginning with an overview of food security, an analysis of key drivers of food insecurity, and nutrition and food security. Part Two examines emerging technologies for plant and animal food security, with subsequent chapters discussing topics from genetic and aquaculture technologies, pest and disease control, environmental and policy issues affecting food security, and an in-depth analysis of water management and methods to reduce post-harvest losses.

  • Plant Water Consumption and Response

    • 1st Edition
    • T.T. Kozlowski
    • English
    Water Deficits and Plant Growth, Volume II: Plant Water Consumption and Response focuses on internal water deficits in plants, the measurement for such deficits, and the identification of physiological and growth responses of herbaceous and woody plants to water deficiency. Partitioned into six chapters, the book discusses the rate of water consumption of agricultural plants. Concerns in this part include evapotranspiration, characteristics of plants, and climate. The discussions move on to the study of water consumption in forests. The methods used in the research, the theoretical considerations, and a review of the results are also discussed. The next part focuses on the relationship of water deficits and physiological processes. This part also introduces the discussions on the effect of water deficiency on the growth of herbaceous plants and trees, including the emergence of diseases related to water deficiency. The book is a valuable source of data for readers who are interested in pursuing studies on the effect of water deficiency on the growth of plants.

  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1st Edition
    • Volume 72
    • English
    Advances in Carbohydrate Chemistry and Biochemistry, part of a long running serial that began in 1945, provides critical and informative articles written by research specialists that integrate the industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. Each article provides a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.

  • Advances in Protein Chemistry and Structural Biology

    • 1st Edition
    • Volume 101
    • English
    The Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

  • Genetic and Genomic Resources for Grain Cereals Improvement

    • 1st Edition
    • Mohar Singh + 1 more
    • English
    Genetic and Genomic Resources For Cereals Improvement is the first book to bring together the latest available genetic resources and genomics to facilitate the identification of specific germplasm, trait mapping, and allele mining that are needed to more effectively develop biotic and abiotic-stress-resis... grains. As grain cereals, including rice, wheat, maize, barley, sorghum, and millets constitute the bulk of global diets, both of vegetarian and non-vegetarian, there is a greater need for further genetic improvement, breeding, and plant genetic resources to secure the future food supply. This book is an invaluable resource for researchers, crop biologists, and students working with crop development and the changes in environmental climate that have had significant impact on crop production. It includes the latest information on tactics that ensure that environmentally robust genes and crops resilient to climate change are identified and preserved.

  • Multiple Sclerosis

    A Mechanistic View
    • 1st Edition
    • Alireza Minagar
    • English
    Multiple Sclerosis: A Mechanistic View provides a unique view of the pathophysiology of multiple sclerosis (MS) and related disorders. As the only book on the market to focus on the mechanisms of MS rather than focusing on the clinical features and treatment of the disease, it describes the role of genetic and environmental factors in the pathogenesis of MS, the role of specific cells in the pathophysiology of the disease, and the pathophysiology of inflammatory and neurodegenerative disorders related to MS. The book provides discussion of neurodegeneration and neuroregeneration, two critical emerging areas of research, as well as detailed discussion of the mechanisms of action of the approved and investigational drugs for treatment of MS and the emerging role of magnetic resonance spectroscopy (MRI) in investigations into MS. It is the only book on the market to offer comprehensive coverage of the known mechanisms of MS and related diseases, and contains contributions from physicians and researchers who are worldwide experts in the field of study.

  • Occupational Neurology

    • 1st Edition
    • Volume 131
    • English
    Occupational Neurology a volume in the Handbook of Clinical Neurology Series, provides a comprehensive overview of the science, clinical diagnosis, and treatment for neurotoxin related neurological and psychiatric disorders. This timely collection provides not only a complete scientific reference on the chemical origin of this class of neurological and psychiatric disorders, but also a practical guide to diagnosis and treatment challenges and best practices. Handbook of Clinical Neurology Series The first volume of the Handbook of Clinical Neurology under the editorship of George Bruyn and Pierre Vinken was published in 1968. In 1982, the series was brought to an interim conclusion with the publication of the cumulative index volume (Volume 44). By that stage, the Handbook had come to represent one of the largest scientific works ever published. It enjoys a high reputation in specialist media circles throughout the world. After the series was concluded in 1982, it was realized that an update of the material was imperative. Accordingly, a revised series was planned and published over the following years, concluding with the publication of another cumulative index to both series (Volume 76-78) in 2002. Since then, George Bruyn has passed away and Pierre Vinken has retired, but the need for a further new series, incorporating advances in the field, again become necessary. Professors Michael J. Aminoff, François Boller and Dick F. Swaab have with enthusiasm taken on the responsibility of supervising the preparation of a third series, the first volumes of which were published in 2003. Now, more than 130 volumes after the first published, the Handbook of Clinical Neurology series continues to have an unparalleled reputation for providing the latest foundational research, diagnosis, and treatment protocols essential for both basic neuroscience research and clinical neurology.

  • Neurocutaneous Syndromes

    • 1st Edition
    • Volume 132
    • Monica P. Islam + 1 more
    • English
    Neurocutaneous Syndromes provides the most updated and comprehensive resource on the disorders that lead to the growth of tumors in various parts of the body, those caused by the abnormal development of cells in an embryo and characterized by the presence of tumors in various parts of the body and eyes, including the nervous system, and by certain differences in the skin. The most common neurocutaneous syndromes include, neurofibromatosis, Sturge-Weber syndrome, tuberous sclerosis, ataxia-telangiectasi... and von Hippel-Lindau disease. Symptoms vary widely and while present early may not express until later in life. As molecular medicine and genetic science is continuing to impact our understanding of neurocutaneous syndromes, this book also includes the latest molecular and genetic science.

  • Concise Illustrated Dictionary of Biocontrol Terms

    • 1st Edition
    • Vladimir V. Gouli + 2 more
    • English
    The Concise Illustrated Dictionary of Biocontrol Terms includes basic terminology related to the biological control of pests, together with state-of-the-art scientific and practical terms, for expedient comprehension and analysis of present, forecasted or in situ pest management problems. In addition, it also provides the names of the most common pesticides and predators commercially available in different continents (Americas, Europe, Asia, Australia, Africa), as well as target pests and diseases of these agents, making it a tangible tool for prompt management actions. The dictionary is copiously illustrated with original pictures clarifying the most commonly used terms and the identity of organisms in biocontrol technology, with content that is both scientifically rigorous and clear. The biological control of pests using living organisms, or products from their activities, is an independent branch of science based on multiple disciplines including general biology, zoology, entomology, phytopathology, microbiology and others. As a result, the field of biological control has its own specific terminology that needs to be understood and applied correctly across this variety of disciplines, including among those approaching the field from a different area of expertise and who may have difficulty understanding the terms used by experts in the field. This compact illustrated guide will appeal to the scientific community working in integrated pest management disciplines, as well as those researching, studying, and working with interest in protecting natural resources at a global, local, and individual level, in a variety of locations including the lab, garden, field, or forest.

  • Domain Specificity of Creativity

    • 1st Edition
    • John Baer
    • English
    Recent research findings have challenged the idea that creativity is domain-general. Domain Specificity of Creativity brings together the research information on domain specificity in creativity -- both the research that supports it and answers to research arguments that might seem to challenge it. The implications for domain specificity affect how we move forward with theories of creativity, testing for creativity, and teaching for creativity. The book outlines what these changes are and how creativity research and applications of that research will change in light of these new findings.

  • Exercise-Cognition Interaction

    Neuroscience Perspectives
    • 1st Edition
    • Terry McMorris
    • English
    Exercise-Cognition Interaction: Neuroscience Perspectives is the only book on the market that examines the neuroscientific correlation between exercise and cognitive functioning. The upsurge in research in recent years has confirmed that cognitive-psychology theory cannot account for the effects of exercise on cognition, and both acute and chronic exercise effect neurochemical and psychophysiological changes in the brain that, in turn, affect cognitive functioning. This book provides an overview of the research into these effects, from theoretical research through current studies that emphasize neuroscientific theories and rationales. It addition, users will find a thorough examination of the effects of exercise interventions on cognitive functioning in special populations, including the elderly, children, and those suffering from a variety of diseases, including schizophrenia, diabetes, and an array of neurological disorders. With contributions from leading researchers in the field, this book will be the go-to resource for neuroscientists, psychologists, medical professionals, and other researchers who need an understanding of the role exercise plays in cognitive functioning.

  • Molecular Aspects of Alcohol and Nutrition

    A Volume in the Molecular Nutrition Series
    • 1st Edition
    • Vinood B. Patel
    • English
    Molecular Aspects of Alcohol and Nutrition is a valuable resource for nutrition researchers and nutritionists who study or treat alcohol-related diseases. Experts from across the field of alcohol research explain how alcohol disrupts normal fat, carbohydrate, and protein metabolic processes occurring in the liver as well as other parts of the body. The book discusses how this can lead to alcoholic liver disease (ALD) as well as contribute to the onset of Type 2 diabetes and the metabolic syndrome. It also explores how alcohol affects nutrient absorption in the gastrointestinal tract and can lead to anemia and reduced amounts of fat soluble vitamins. This book explores both the primary and secondary consequences of alcohol consumption. Chapters in the first section investigate the basic science of alcohol metabolism – focusing on how alcohol and its toxic metabolites disrupt and impair normal nutrient regulation at the molecular level. Further chapters explore how alcohol affects many extra-hepatic organs and tissues as well as the secondary consequences of alcohol consumption such as reduced levels of minerals like magnesium, calcium, and trace elements like zinc.

  • Humpback Dolphins (Sousa spp.): Current Status and Conservation, Part 1

    • 1st Edition
    • Volume 72
    • English
    Humpback Dolphins (Sousa spp.): Current Status and Conservation, Part 1 is part of Advances in Marine Biology, a series that has been providing in-depth and up-to-date reviews on all aspects of marine biology since 1963 — more than 50 years of outstanding coverage from a reference that is well known for its contents and editing. This latest addition to the series includes updates on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology, and biological oceanography. Specialty areas for the series include marine science, both applied and basic, a wide range of topical areas from all corners of marine ecology, oceanography, fisheries management, and molecular biology, and the full range of geographic areas from polar seas to tropical coral reefs.

  • Side Effects of Drugs Annual

    A worldwide yearly survey of new data in adverse drug reactions
    • 1st Edition
    • Volume 37
    • English
    Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions was first published in 1977, and has been continually published as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs. Each Annual provides clinicians and medical investigators with a reliable and critical survey of new data and trends in the area of adverse drug reactions and interactions, with an international team of specialists contributing their expertise each year.

  • The Scientist's Guide to Cardiac Metabolism

    • 1st Edition
    • Michael Schwarzer + 1 more
    • English
    The Scientists Guide to Cardiac Metabolism combines the basic concepts of substrate metabolism, regulation, and interaction within the cell and the organism to provide a comprehensive introduction into the basics of cardiac metabolism. This important reference is the perfect tool for newcomers in cardiac metabolism, providing a basic understanding of the metabolic processes and enabling the newcomer to immediately communicate with the expert as substrate/energy metabolism becomes part of projects. The book is written by established experts in the field, bringing together all the concepts of cardiac metabolism, its regulation, and the impact of disease.

  • Isotope Labeling of Biomolecules – Labeling Methods

    • 1st Edition
    • Volume 565
    • English
    Isotope Labeling of Biomolecules – Labeling Methods, the latest volume of the Methods in Enzymology series contains comprehensive information on stable isotope labeling methods and applications for biomolecules.

  • Translational Research in Coronary Artery Disease

    Pathophysiology to Treatment
    • 1st Edition
    • Wilbert S. Aronow + 1 more
    • English
    Translational Research in Coronary Artery Disease: Pathophysiology to Treatment covers the entire spectrum of basic science, genetics, drug treatment, and interventions for coronary artery disease. With an emphasis on vascular biology, this reference fully explains the fundamental aspects of coronary artery disease pathophysiology. Included are important topics, including endothelial function, endothelial injury, and endothelial repair in various disease states, vascular smooth muscle function and its interaction with the endothelium, and the interrelationship between inflammatory biology and vascular function. By providing this synthesis of current research literature, this reference allows the cardiovascular scientist and practitioner to access everything they need from one source.

  • Genomics and Society

    Ethical, Legal, Cultural and Socioeconomic Implications
    • 1st Edition
    • Dhavendra Kumar + 1 more
    • English
    Genomics and Society; Ethical, Legal-Cultural, and Socioeconomic Implications is the first book to address the vast and thorny web of ELSI topics identified as core priorities of the NHGRI in 2011. The work addresses fundamental issues of biosociety and bioeconomy as the revolution in biology moves from research lab to healthcare system. Of particular interest to healthcare practitioners, bioethicists, and health economists, and of tangential interest to the gamut of applied social scientists investigating the societal impact of new medical paradigms, the work describes a myriad of issues around consent, confidentiality, rights, patenting, regulation, and legality in the new era of genomic medicine.

  • The Health of Populations

    Beyond Medicine
    • 1st Edition
    • Jack James
    • English
    The Health of Populations: Beyond Medicine uses current research and in-depth analysis to provide insights into the issues and challenges of population health; a subject of increasing concern, due largely to rapid population growth, population aging, rising costs and diminishing resources, health inequality, and the global rise in noncommunicable diseases. Reducing the global burden of disease requires prevention of disease incidence, which is achievable through reduction of exposure to primary (behavioral) and secondary (biomedical) risk factors. The 15 chapters of the book are divided into three sections that focus on the science of health, the harm of medicine, and how to achieve optimal health. By highlighting the benefits of preventing incidence of disease, this book illustrates how biomedicine needs to be repositioned form being the dominant approach in healthcare to being an adjunct to behavioral, legislative, social, and other preventive means for optimizing population health.

  • Movement Disorders in Childhood

    • 2nd Edition
    • Harvey S. Singer + 3 more
    • English
    Movement Disorders in Childhood, Second Edition, provides the most up-to-date information on the diseases and disorders that affect motor control, an important area of specialization within child neurology. Over the past several decades, advances in genetics, neuroimaging, neurophysiology, and other areas of neuroscience have provided new understanding of the underlying etiologies and mechanisms of these conditions as well as new opportunities for more accurate diagnosis and effective treatment. This new edition builds upon the success of the first edition, with comprehensive scientific and clinical updates of all chapters. In addition, there are new chapters on hereditary spastic paraplegia, quantitative motor assessments, autoimmune disorders, and movement disorders in the developmental neuropsychiatric disorders ADHD, OCD, and autism. Additional materials are provided on the latest in drug treatments, computer based strategies for genetic diagnosis, and helpful videos for phenomenology.

  • Efficient Livestock Handling

    The Practical Application of Animal Welfare and Behavioral Science
    • 1st Edition
    • Bonnie V. Beaver + 1 more
    • English
    Efficient Livestock Handling: The Practical Application of Animal Welfare and Behavioral Science brings together the science-based disciplines of animal behavior and welfare to discuss how knowledge of one area (behavior) can be used to promote the other. Emphasis is on cattle and horses, but swine, sheep, and goats are also covered. Three major areas are included and integrated into a practical approach to working with the various species. Basic behavior as it applies to handling is discussed, with differences noted between species. The connections of behavior and handling are covered, and practical applications discussed, both with a liberal use of pictures and videos to bring the concepts to life.

  • Vascular Responses to Pathogens

    • 1st Edition
    • Felicity N.E. Gavins + 1 more
    • English
    Vascular Responses to Pathogens focuses on the growing research from leaders in the field for both the short and long-term impact of pathogens on the vasculature. It discusses various organisms, including bacteria, parasites, and viruses, and their role in key events leading to vascular disease. Formatted to discuss the topic of the interaction of pathogens with the vascular rather than individual diseases described separately, this reference demonstrates that common mechanisms are at play in many different diseases because they have a similar context, their vasculature. This all-inclusive reference book is a must-have tool for researchers and practicing clinicians in the areas of vascular biology, microvasculature, cardiology, and infectious disease.

  • Signal Transduction

    • 3rd Edition
    • ljsbrand M. Kramer
    • English
    A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor – ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 93
    • English
    Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology, containing comprehensive reviews of the most current research in applied microbiology. Users will find invaluable references and information on a variety of areas, including protozoan grazing of freshwater biofilms, metals in yeast fermentation processes, the interpretation of host-pathogen dialogue through microarrays, and the role of polyamines in bacterial growth and biofilm formation. Eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndrome.

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 76
    • English
    Advances in Food and Nutrition Research recognizes the integral relationship between the food and nutritional sciences, bringing together outstanding and comprehensive reviews that highlight this relationship. The book contains contributions that detail scientific developments in the broad areas of food science and nutrition, providing those in academia and industry with the latest information on emerging research in these constantly evolving sciences.

  • Computational Neurostimulation

    • 1st Edition
    • Volume 222
    • English
    Computational Neurostimulation, the latest volume in the Progress in Brain Research series provides an introduction to a nascent field with contributions from leading researchers. In addition, it addresses a very timely and relevant issue which has long been known to require more treatment.

  • Computational Immunology

    Models and Tools
    • 1st Edition
    • Josep Bassaganya-Riera
    • English
    Computational Immunology: Models and Tools encompasses the methodological framework and application of cutting-edge tools and techniques to study immunological processes at a systems level, along with the concept of multi-scale modeling. The book's emphasis is on selected cases studies and application of the most updated technologies in computational modeling, discussing topics such as computational modeling and its usage in immunological research, bioinformatics infrastructure, ODE based modeling, agent based modeling, and high performance computing, data analytics, and multiscale modeling. There are also modeling exercises using recent tools and models which lead the readers to a thorough comprehension and applicability. The book is a valuable resource for immunologists, computational biologists, bioinformaticians, biotechnologists, and computer scientists, as well as all those who wish to broaden their knowledge in systems modeling.

  • New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System – Part B

    • 1st Edition
    • Volume 221
    • English
    New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System - Part B is the latest volume from Progress in Brain Research focusing on new trends in basic and clinical research of glaucoma. This established international series examines major areas of basic and clinical research within neuroscience, as well as emerging subfields.

  • Biodiversity of the Southern Ocean

    • 1st Edition
    • Bruno David + 1 more
    • English
    The Southern Ocean surrounding the Antarctic continent is vast, in particular, its history, its isolation, and climate, making it a unique "laboratory case" for experimental evolution, adaptation and ecology. Its evolutionary history of adaptation provide a wealth of information on the functioning of the biosphere and its potential. The Southern Ocean is the result of a history of nearly 40 million years marked by the opening of the Straits south of Australia and South America and intense cooling. The violence of its weather, its very low temperatures, the formation of huge ice-covered areas, as its isolation makes the Southern Ocean a world apart. This book discusses the consequences for the evolution, ecology and biodiversity of the region, including endemism, slowed metabolism, longevity, gigantism, and its larval stages; features which make this vast ocean a "natural laboratory" for exploring the ecological adaptive processes, scalable to work in extreme environmental conditions. Today, biodiversity of the Southern Ocean is facing global change, particularly in regional warming and acidification of water bodies. Unable to migrate further south, how will she cope, if any, to visitors from the North?

  • Epigenetic Gene Expression and Regulation

    • 1st Edition
    • Suming Huang + 2 more
    • English
    Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples.

  • Food Fraud

    • 1st Edition
    • John M. Ryan
    • English
    Food Fraud provides an overview of the current state on the topic to help readers understand which products are being impacted, how pervasive food fraud is, and what laws are in effect across the developed world. As international food trade increases, food processors, distributors, and consumers are purchasing more and more food from foreign countries that, in many cases, have inadequate oversight or control over what is coming into our supermarkets, restaurants, and refrigerators. This book is an essential quick reference that will familiarize readers with the latest issues surrounding the food industry.

  • Nicotine Use in Mental Illness and Neurological Disorders

    • 1st Edition
    • Volume 124
    • English
    Nicotine Use in Mental Illness and Neurological Disorders, a volume in the International Review of Neurobiology series, is a comprehensive overview of the state-of-the-art research into nicotine use in mental illness and neurological disorders. It reviews current knowledge and understanding, also provides a starting point for researchers and practitioners entering the field.

  • Nutritional Composition of Fruit Cultivars

    • 1st Edition
    • Monique Simmonds + 1 more
    • English
    Nutritional Composition of Fruit Cultivars provides readers with the latest information on the health related properties of foods, making the documentation of the nutritive value of historical cultivars especially urgent, especially before they are lost and can't be effectively compared to modern cultivars. Because there is considerable diversity and a substantial body of the compositional studies directed towards commercial varieties, this information is useful for identifying traits and features that may be transposed from one variety to another. In addition, compositional and sensory features may also be used for commercialization and to characterize adulteration. Detailed characterization of cultivars can be used to identify "super-foods". Alternatively, unmasked historical cultivars may be the focus of reinvigorated commercial practices. Each chapter in this book has sections on the botanical aspects, the composition of traditional or ancient cultivars, the composition of modern cultivars, a focus on areas of research, the specialty of the communicating author of each chapter, and summary points.

  • Molecular Mechanisms that Orchestrate the Assembly of Antigen Receptor Loci

    • 1st Edition
    • Volume 128
    • English
    Molecular Mechanisms That Orchestrate the Assembly of Antigen Receptor Loci, the latest volume in the Advances in Immunology series focuses on the generation of an effective immune response to invading pathogens As B and T lymphocytes are characterized by the expression of antigen receptors that specifically recognize determinants expressed on pathogens, this volume discusses how antigen receptors are synthesized in B and T lymphocytes.

  • Meyler's Side Effects of Drugs

    The International Encyclopedia of Adverse Drug Reactions and Interactions
    • 16th Edition
    • Jeffrey K. Aronson
    • English
    Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, Sixteenth Edition, Seven Volume Set builds on the success of the 15 previous editions, providing an extensively reorganized and expanded resource that now comprises more than 1,500 individual drug articles with the most complete coverage of adverse reactions and interactions found anywhere. Each article contains detailed and authoritative information about the adverse effects of each drug, with comprehensive references to the primary literature, making this a must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company. The online version of the book provides an unparalleled depth of coverage and functionality by offering convenient desktop access and enhanced features such as increased searchability, extensive internal cross-linking, and fully downloadable and printable full-text, HTML or PDF articles.

  • Essential Chemistry for Formulators of Semisolid and Liquid Dosages

    • 1st Edition
    • Vitthal S. Kulkarni + 1 more
    • English
    A needed resource for pharmaceutical scientists and cosmetic chemists, Essential Chemistry for Formulators of Semisolid and Liquid Dosages provides insight into the basic chemistry of mixing different phases and test methods for the stability study of nonsolid formulations. The book covers foundational surface/colloid chemistry, which forms the necessary background for making emulsions, suspensions, solutions, and nano drug delivery systems, and the chemistry of mixing, which is critical for further formulation of drug delivery systems into semisolid (gels, creams, lotions, and ointments) or liquid final dosages. Expanding on these foundational principles, this useful guide explores stability testing methods, such as particle size, rheological/viscosit... microscopy, and chemical, and closes with a valuable discussion of regulatory issues. Essential Chemistry for Formulators of Semisolid and Liquid Dosages offers scientists and students the foundation and practical guidance to make and analyze semisolid and liquid formulations.

  • Genetic Control of Malaria and Dengue

    • 1st Edition
    • Zach N. Adelman
    • English
    Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown.

  • Artificial Neural Network for Drug Design, Delivery and Disposition

    • 1st Edition
    • Munish Puri + 4 more
    • English
    Artificial Neural Network for Drug Design, Delivery and Disposition provides an in-depth look at the use of artificial neural networks (ANN) in pharmaceutical research. With its ability to learn and self-correct in a highly complex environment, this predictive tool has tremendous potential to help researchers more effectively design, develop, and deliver successful drugs. This book illustrates how to use ANN methodologies and models with the intent to treat diseases like breast cancer, cardiac disease, and more. It contains the latest cutting-edge research, an analysis of the benefits of ANN, and relevant industry examples. As such, this book is an essential resource for academic and industry researchers across the pharmaceutical and biomedical sciences.

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