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Elsevier

Books in Life sciences

  • Bioprocess Engineering

    Kinetics, Sustainability, and Reactor Design
    • 2nd Edition
    • Shijie Liu
    • English
    Bioprocess Engineering: Kinetics, Sustainability, and Reactor Design, Second Edition, provides a comprehensive resource on bioprocess kinetics, bioprocess systems, sustainability, and reaction engineering. Author Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics, batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering, also introducing key principles that enable bioprocess engineers to engage in analysis, optimization, and design with consistent control over biological and chemical transformations. The quantitative treatment of bioprocesses is the central theme in this book, with more advanced techniques and applications being covered in depth. This updated edition reflects advances that are transforming the field, ranging from genetic sequencing, to new techniques for producing proteins from recombinant DNA, and from green chemistry, to process stability and sustainability. The book introduces techniques with broad applications, including the conversion of renewable biomass, the production of chemicals, materials, pharmaceuticals, biologics, and commodities, medical applications, such as tissue engineering and gene therapy, and solving critical environmental problems.

  • Na Channels from Phyla to Function

    • 1st Edition
    • Volume 78
    • English
    Na Channels from Phyla to Function, the latest volume in the Current Topics in Membranes series, is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume offers an up-to-date presentation of the current knowledge in the field of Na Channels.

  • Encyclopedia of Applied Plant Sciences

    • 2nd Edition
    • Brian Thomas
    • English
    Encyclopedia of Applied Plant Sciences, Second Edition, Three Volume Set presents both foundational and applied information on plants used by humans as sources of food, raw materials, and amenity purposes. It highlights how the underlying science and information links through to applications in practical situations. Since the last edition was published, the role of applied science in agricultural production has been brought into greater focus as fluctuations in global food production feed through into prices and availability to consumers. At the same time, technological advances are changing the way plant science is done. This Second Edition has been expanded to include specific chapters on the leading crops and crop-types, as well as updated chapters on plant development, photosynthesis, metabolism, nutrition, reproduction, seed biology, plant pests and diseases, weed biology, and responses to environmental stresses. The updated chapters reflect progress, particularly in genome sequencing and molecular genetics and biotechnology, including genetic modification, that have taken place since the first edition was published. In addition, the book places these developments in the wider context of biodiversity, food security, intellectual property, and ethical considerations.

  • Peptide, Protein and Enzyme Design

    • 1st Edition
    • Volume 580
    • English
    De Novo Enzyme Design, the newest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume includes the design of metal binding maquettes, insertion of non-natural cofactors, Cu metallopeptides, non-covalent interactions in peptide assemblies, peptide binding and bundling, heteronuclear metalloenzymes, florinated peptides, De Novo imaging agents, and protein-protein interaction.

  • Seafood Authenticity and Traceability

    A DNA-based Pespective
    • 1st Edition
    • Amanda Naaum + 1 more
    • English
    Seafood Authenticity and Traceability: a DNA-based Pespective is a concise reference showcasing the latest developments in the field. Written for those in food authenticity who may not have a technical molecular biology background, the book covers methods used for DNA analysis and an overview of their applications in fish and seafood, also providing reviews of the technology and processes for each method. It offers a practical and succinct overview of the relationship between accurate identification, traceability, sustainability, and safety of seafood, including an overview of the supply chain and the industry's need for improved traceability.

  • Advances in Marine Biology

    • 1st Edition
    • Volume 74
    • English
    Advances in Marine Biology has been providing in-depth and up-to-date reviews on all aspects of marine biology since 1963 — more than 50 years of outstanding coverage from a comprehensive serial that is well known for its contents and editing. This latest addition to the series includes updates on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology, and biological oceanography. Specialty areas for the series include marine science, both applied and basic, a wide range of topical areas from all areas of marine ecology, oceanography, fisheries management, and molecular biology, and the full range of geographic areas from polar seas to tropical coral reefs.

  • Metabolomics and Microbiomics

    Personalized Medicine from the Fetus to the Adult
    • 1st Edition
    • Vassilios Fanos
    • English
    Metabolomics and Microbiomics: Personalized Medicine from the Fetus to the Adult encompasses the most recent advances on the usage of metabolomics and microbiome research to improve disease diagnosis and healthcare. Medicine is changing from epidemiologic, descriptive, reductionist, and reactive approaches to individualized, predictive, and holistic ones by applying microbiomics to understand the functionality of the human body. The book discusses topics such as systems biology approaches, omics technologies, perinatal programming, and personalized medicine. It also discusses the ethical implications of microbiomics research and new pathways of research, such as renal regenerative medicine, gender medicine in perinatology, and animals and the science of healing. The book is a valuable resource for medical professionals and researchers in metabolomics, nutrition, microbiology, and personalized-predict... medicine. The book also will appeal to non-specialized professionals who may take advantage of its captivating and simple language.

  • Logistics Engineering and Health

    • 1st Edition
    • Hayfa Zgaya + 1 more
    • English
    This book presents the research that resulted from a fruitful collaboration between many CNRS research laboratories, health establishments and industrialists. This research contributes to the study and the development of logistical systems, in particular health-oriented logistical systems, in order to manage and optimize physical, informational and financial flows. The authors examine optimization and modeling methods to facilitate decision support for the management of logistics systems in the health field, including solutions to problems encountered in the management of logistics flows and the study of systems incorporating these flows. In the first chapter, logistics engineering is presented whilst the second chapter introduces the study of real cases of transport, management crisis and warehouse management logistics systems. The third chapter is devoted to the study of hospital systems and emergency services and in the fourth chapter, the authors highlight the operational aspect of the hospital system thanks to an innovative modeling approach. Finally, mathematical and algorithmic models of scheduling, and dynamic orchestration of the collaborative workflow by a multi-agent system, are introduced.

  • The Resolution Revolution: Recent Advances In cryoEM

    • 1st Edition
    • Volume 579
    • English
    cryoEM, a new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods and new developments in recording images, the creation, evaluation and validation of 3D maps from the images, model building into maps and refinement of the resulting atomic structures, and applications of essentially single particle methods to helical structures and to sub-tomogram averaging.

  • Progress in Mosquito Research

    • 1st Edition
    • Volume 51
    • English
    Progress in Mosquito Research provides readers with the latest interdisciplinary reviews on the topic. It is an essential reference source for invertebrate physiologists, neurobiologists, entomologists, zoologists, and insect chemists, with Volume 51 focusing on recent progress in mosquito research.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 96
    • English
    The Advances in Applied Microbiology series, first published in 1959, continues to be one of the most widely read and authoritative review sources in microbiology. The series contains comprehensive reviews of the most current research in applied microbiology and includes recent research on the role staphylococcus aureus aggregation and coagulation mechanisms, along with analysis of microbial communities in the deep biosphere.

  • Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods

    • 1st Edition
    • Volume 105
    • English
    Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods is the latest volume in the popular Advances in Protein Chemistry and Structural Biology series, an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

  • Fundamentals of Toxicology

    Essential Concepts and Applications
    • 1st Edition
    • PK Gupta
    • English
    Fundamentals of Toxicology: Essential Concepts and Applications provides a crisp, easy-to-understand overview of the most important concepts, applications, and ideas needed to learn the basics of toxicology. Written by a pre-eminent toxicologist with over five decades of teaching experience, this comprehensive resource offers the hands-on knowledge needed for a strong foundation in the wide field of toxicology. Fundamentals of Toxicology includes a clear structure divided into five units to assist learning and understanding. The first unit provides extensive coverage on the background of toxicology including commonly used definitions and historical perspective, while following units cover: basic concepts; regulatory requirements and good laboratory practices, including types of toxicology testing and evaluation; toxic agents and adverse effects on health; and analytical, forensic, and diagnostic toxicology. This is an essential book for advanced students in toxicology and across the biomedical sciences, life sciences, and environmental sciences who want to learn the concepts of toxicology, as well as early researchers needing to refresh outside of their specialty.

  • Salience Network of the Human Brain

    • 1st Edition
    • Lucina Q. Uddin
    • English
    Salience Network of the Human Brain focuses on the multiple sources of stimuli that compete for our attention, providing interesting discussions on how the relative salience—importance or prominence—of each of these inputs determines which ones we choose to focus on for more in-depth processing. The salience network is a collection of regions of the brain that select which stimuli are deserving of our attention. The network has key nodes in the insular cortex and is critical for detecting behaviorally relevant stimuli and for coordinating the brain’s neural resources in response to these stimuli. The insular cortex is a complex and multipurpose structure that plays a role in numerous cognitive functions related to perception, emotion, and interpersonal experience—and the failure of this network to function properly can lead to numerous neuropsychiatric disorders, including autism spectrum disorder, psychosis, and dementia.

  • Medical Biosensors for Point of Care (POC) Applications

    • 1st Edition
    • Roger Narayan
    • English
    Medical Biosensors for Point of Care (POC) Applications discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care. Part 1 covers the fundamentals of medical biosensors for point-of-care applications. Chapters in part 2 go on to look at materials and fabrication of medical biosensors while the next part looks at different technologies and operational techniques. The final set of chapters provide an overview of the current applications of this technology. Traditionally medical diagnostics have been dependent on sophisticated technologies which only trained professionals were able to operate. Recent research has focused on creating point-of-care diagnostic tools. These biosensors are miniaturised, portable, and are designed to be used at the point-of-care by untrained individuals, providing real-time and remote health monitoring.

  • Systemic Inflammatory Disease and the Eye

    • 1st Edition
    • W. J. Dinning
    • English
    Systemic Inflammatory Disease and the Eye present an overview of the systemic conditions associated with ocular inflammation. It discusses the factors for ocular connection in some conditions. It addresses the nature of ocular lesions and eye infections. Some of the topics covered in the book are the symptoms of inflammation of the eye; the aetiology of sarcoidosis; posterior segment inflammation; pathology and immunology of systemic vasculitis syndromes; aetiology of polyarteritis nodosa; diagnosis of systemic lupus erythematosus; and the different types of Sjogren’s syndrome. The pathology and immunopathology of Keratoconjunctivitis Sicca are fully covered. The diagnosis of rheumatoid arthritis is discussed in detail. The text describes in depth the rheumatoid factors and histopathology of joint lesions. The diagnosis of juvenile chronic polyarthritis is presented completely. A chapter is devoted to the epidemiology and clinical features of ankylosing spondylitis. The book can provide useful information to ophthalmologists, doctors, chemists, students, and researchers.

  • Laterality in Sports

    Theories and Applications
    • 1st Edition
    • Florian Loffing + 3 more
    • English
    Laterality in Sports: Theories and Applications summarizes recent research on the neurophysiological foundations of handedness, and how left or right lateralization (affecting primary hand use, foot use, and eye use) affects motor control, performance outcome, skill acquisition, and achievement of sports expertise—both for one-on-one sports and team sports. As laterality research has matured, greater focus has been given to applications in human endeavours and, in particular, sport. The book examines performance within individual sports, and discusses the coaching ramifications of coaching to a specific lateralization preference.

  • Obesity, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 45-3
    • Caroline M. Apovian + 1 more
    • English
    This issue of Endocrinology and Metabolism Clinics, guest edited by Drs. Caroline M. Apovian and Nawfal Istfan, is devoted to Obesity. Articles in this comprehensive issue include: Guidelines for Obesity Management; Obesity is a Disease; Pharmacotherapy for Obesity; Bariatric Surgery Mechanisms; Diabetes Treatment in the Patient with Obesity; Adipose Tissue: Inflammation and the Endocrine Organ; Behavioral Treatment of the Patient with Obesity; The Role of Macronutrient Content in the Diet for Weight Loss and Weight Maintenance; Substrate Oxidation and Brown Adipose Tissue; Brown and Beige Adipose Tissue: Therapy for Obesity?; Ethnic Differences in Diabetes Lipids HTN and Obesity; Genetics of Bariatric Surgery Outcomes; Leptin and Hormones: Energy Homeostatis; Bariatric Surgery Clinical Outcomes; Medical Devices for Obesity; Adolescent Bariatric Surgery; Psychological Aspects of Obesity; and Nutrient Timing.

  • Negative Affective States and Cognitive Impairments in Nicotine Dependence

    • 1st Edition
    • F. Scott Hall + 2 more
    • English
    Negative Affective States and Cognitive Impairments in Nicotine Dependence is the only book of its kind that addresses nicotine use and abuse in the context of negative reinforcement mechanisms. Written and edited by leading investigators in addiction, affective, genetic, and cognitive research, it provides researchers and advanced students with an overview of the clinical bases of these effects, allowing them to fully understand the various underlying dysfunctions that drive nicotine use in different individuals. In addition, this book examines animal models that researchers have utilized to investigate the biological bases of these dysfunctions. The combination of clinical and preclinical approaches to understanding nicotine dependence makes this book an invaluable resource for researchers and practitioners seeking to develop targeted treatments aimed at ameliorating symptoms of nicotine dependence, as well as identifying premorbid differences in affective or cognitive function.

  • Cancer Stem Cells

    Targeting the Roots of Cancer, Seeds of Metastasis, and Sources of Therapy Resistance
    • 1st Edition
    • Huiping Liu + 1 more
    • English
    Cancer Stem Cells: Targeting the Roots of Cancer, Seeds of Metastasis, and Sources of Therapy Resistance introduces the basic concepts and advanced understanding of cancer stem cells, covering general overviews, organ-specific identifications, and their characteristic mechanisms. The book also explores innovative therapeutic strategies in preclinical and clinical trials to target cancer stem cells, remove the roots of cancer, eliminate the seeds of metastasis, overcome the resistance of therapies, and contribute to the eradication of cancer. The book includes contributions from leading, worldwide experts in the field, helping readers embrace new hope in their quest to eradicate cancer with emerging clinical trials on treating cancer stem cells in combination with other therapies.

  • Nanoscience in Dermatology

    • 1st Edition
    • Michael R. Hamblin + 2 more
    • English
    Nanoscience in Dermatology covers one of the two fastest growing areas within dermatological science, nanoscience and nanotechnology in dermatology. Recently, great progress has been made in the research and development of nanotechnologies and nanomaterials related to various applications in medicine and, in general, the life sciences. There is increasing enthusiasm for nanotechnology applications in dermatology (drug delivery, diagnostics, therapeutics, imaging, sensors, etc.) for understanding skin biology, improving early detection and treatment of skin diseases, and in the design and optimization of cosmetics. Light sensitive nanoparticles have recently been explored, opening a new era for the combined applications of light with nanotechnology, also called photonanodermatology... However, concerns have been raised regarding the adverse effects of intentional and unintentional nanoparticle exposure and their toxicity. Written by experts working in these exciting fields, this book extensively covers nanotechnology applications, together with the fundamentals and toxicity aspects. It not only addresses current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing scientists and dermatologists with a clear understanding of the advantages and challenges of nanotechnology in skin medicine.

  • Protein Byproducts

    Transformation from Environmental Burden Into Value-Added Products
    • 1st Edition
    • Gurpreet Singh Dhillon
    • English
    Protein Byproducts: Transformation from Environmental Burden into Value-Added Products deals with the added value of proteinaceous waste byproducts, discussing in detail the different sources of protein-rich byproducts, their extraction, recovery, and characterization. The book provides thorough insights into different protein modification techniques to extend the product portfolio using these waste byproducts. Divided between three main sections, the book covers various feedstock resources, such as animal-derived/plant... proteins, marine waste-derived proteins, protein extraction and recovery methods, and related technical issues including modification and conversion technologies for the production of high value bioproducts. It contains contributions from experts in the fields of applied industrial microbiology, engineering, bioprocess technology, protein chemistry, food chemistry, agriculture, plant sciences, environmental science, and waste management, serving as a comprehensive reference for students and research scientists in the food and agriculture industries.

  • Nutrient Delivery

    • 1st Edition
    • Alexandru Grumezescu
    • English
    Nutrient Delivery: Nanotechnology in the Agri-Food Industry, Volume Five, discusses the fabrication, merits, demerits, applications, and bioavailability enhancement mechanisms of various nanodelivery systems. Recent developments in various nanodelivery systems are also highlighted. Volume 5 contains twenty chapters, prepared by outstanding international researchers from Argentina, Brazil, Canada, China, Croatia, India, Iran, Ireland, México, Pakistan, Portugal, Serbia, Sri Lanka, and the United States. In recent years, the delivery of micronutrients at nanoscale has been widely studied as these systems have the potential to improve bioavailability, enable controlled release and enhance stability of food bioactives to a greater extent. The nanodelivery systems typically consist of the food bioactive compound encapsulated and stabilized in food grade ingredients such as lipids, proteins or polysaccharides with diameters ranging from 10 nm to 1000 nm. Among these, the lipid based delivery systems such as nanoemulsions, solid lipid nanoparticles, nanoliposomes and micelles are widely studied for the delivery of lipophilic bioactive compounds. These delivery vehicles improve the solubility, permeability, stability and bioavailability of the lipophilic compounds thereby enhancing their potential for oral delivery and functional food development. On the other hand, the hydrophilic bioactives are delivered through protein, polysaccharide or biopolymer based colloidal nanosystems such as hydrogels, nanogels and polymer nanoparticles. The major concern other than solubility is the intestinal permeability of the micronutrients. For instance, the delivery system for compounds with poor intestinal permeability and low solubility need to be carefully designed using suitable lipids and surfactants.

  • Life-Threatening Effects of Antipsychotic Drugs

    • 1st Edition
    • Peter Manu + 2 more
    • English
    Life-Threatening Effects of Antipsychotic Drugs describes in detail more than 20 life-threatening effects associated with antipsychotics, presents the best available data on their incidence and case fatality, and gives comprehensive advice on diagnosis, management and preventive strategies. In addition, the book discusses the benefit of antipsychotic medication in a range of therapeutic indications, and demonstrates the gain in life-expectancy associated with clozapine use in severe mental illness despite its serious, potentially life-threatening adverse effects.

  • Netter's Concise Neurology Updated Edition

    • 1st Edition
    • Karl E. Misulis + 1 more
    • English
    More than 200 exquisite, hand-painted illustrations - created by, and in the style of, master medical illustrator Frank H. Netter, MD - capture the essential clinical aspects of over 200 major neurologic disorders seen in hospital and office practice. The new enhanced Expert Consult eBook version features online and offline access to test-yourself images, multiple-choice questions, note-taking and highlighting capabilities, the fully searchable text, and much more. With its masterful combination of artwork, succinct text, and tables, and its compact format, Netter's Concise Neurology delivers quick and convenient access to vital clinical knowledge! This "updated" first edition includes an eBook with the print. The ExpertConsult eBook includes test-yourself images, and notes and highlighting capabilities. All other content is the same as the 2007 1st edition.

  • Conquering RAS

    From Biology to Cancer Therapy
    • 1st Edition
    • Asfar Azmi
    • English
    Conquering RAS: From Biology to Cancer Therapy provides introductory knowledge on how modern RAS biology is taking shape in light of newer technological development. Each chapter is written in a manner that emphasizes simplicity and readability for both new investigators and established researchers. While RAS biology has been intensively studied for more than three decades, we are yet to see any effective therapeutics that could interfere in the signaling cascade regulated by this master oncogene. The book covers topics ranging from basic RAS biology, to translational biology and drug discovery applications. These topics will be appealing to basic researchers working in labs who seek deeper understanding of the modern concepts in RAS research. On the other side, the oncologist at the patient’s bedside will find the book useful as they routinely face the daunting task of treating patients that predominantly have a disease driven by oncogenic KRAS.

  • Mesenchymal Stromal Cells

    Translational Pathways to Clinical Adoption
    • 1st Edition
    • Hematti Peiman + 1 more
    • English
    Mesenchymal Stromal Cells: Translational Pathways to Clinical Adoption provides the latest information on the necessary steps for successful production of stem cells for a clinical trial. Written by professionals with hands-on experience in bringing MSC therapies to the clinic, and building on the biology and mechanisms of action, this unique book covers the development and production of clinical-grade products that are suitable for use in humans. From design of a cell production facility, to obtaining regulatory approval and reimbursement issues, it is a useful guide for researchers and administrators across biomedical research.

  • Advances in Food Authenticity Testing

    • 1st Edition
    • Gerard Downey
    • English
    Advances in Food Authenticity Testing covers a topic that is of great importance to both the food industry whose responsibility it is to provide clear and accurate labeling of their products and maintain food safety and the government agencies and organizations that are tasked with the verification of claims of food authenticity. The adulteration of foods with cheaper alternatives has a long history, but the analytical techniques which can be implemented to test for these are ever advancing. The book covers the wide range of methods and techniques utilized in the testing of food authenticity, including new implementations and processes. The first part of the book examines, in detail, the scientific basis and the process of how these techniques are used, while other sections highlight specific examples of the use of these techniques in the testing of various foods. Written by experts in both academia and industry, the book provides the most up-to-date and comprehensive coverage of this important and rapidly progressing field.

  • Chromatin Signaling and Diseases

    • 1st Edition
    • Olivier Binda + 1 more
    • English
    Chromatin Signaling and Diseases covers the molecular mechanisms that regulate gene expression, which govern everything from embryonic development, growth, and human pathologies associated with aging, such as cancer. This book helps researchers learn about or keep up with the quickly expanding field of chromatin signaling. After reading this book, clinicians will be more capable of explaining the mechanisms of gene expression regulation to their patients to reassure them about new drug developments that target chromatin signaling mechanisms. For example, several epigenetic drugs that act on chromatin signaling factors are in clinical trials or even approved for usage in cancer treatments, Alzheimer's, and Huntington's diseases. Other epigenetic drugs are in development to regulate various class of chromatin signaling factors. To keep up with this changing landscape, clinicians and doctors will need to stay familiar with genetic advances that translate to clinical practice, such as chromatin signaling. Although sequencing of the human genome was completed over a decade ago and its structure investigated for nearly half a century, molecular mechanisms that regulate gene expression remain largely misunderstood. An emerging concept called chromatin signaling proposes that small protein domains recognize chemical modifications on the genome scaffolding histone proteins, facilitating the nucleation of enzymatic complexes at specific loci that then open up or shut down the access to genetic information, thereby regulating gene expression. The addition and removal of chemical modifications on histones, as well as the proteins that specifically recognize these, is reviewed in Chromatin Signaling and Diseases. Finally, the impact of gene expression defects associated with malfunctioning chromatin signaling is also explored.

  • Marine Ecotoxicology

    Current Knowledge and Future Issues
    • 1st Edition
    • Julián Blasco + 3 more
    • English
    Marine Ecotoxicology: Current Knowledge and Future Issues is the first unified resource to cover issues related to contamination, responses, and testing techniques of saltwater from a toxicological perspective. With its unprecedented focus on marine environments and logical chapter progression, this book is useful to graduate students, ecotoxicologists, risk assessors, and regulators involved or interested in marine waters. As human interaction with these environments increases, understanding of the pollutants and toxins introduced into the oceans becomes ever more critical, and this book builds a foundation of knowledge to assist scientists in studying, monitoring, and making decisions that affect both marine environments and human health. A team of world renowned experts provide detailed analyses of the most common contaminants in marine environments and explain the design and purpose of toxicity testing methods, while exploring the future of ecotoxicology studies in relation to the world’s oceans. As the threat of increasing pollution in marine environments becomes an ever more tangible reality, Marine Ecotoxicology offers insights and guidance to mitigate that threat.

  • Imaging the Addicted Brain

    • 1st Edition
    • Volume 129
    • English
    Imaging the Addicted Brain, the latest volume in the International Review of Neurobiology series will appeal to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume focusses on the imaging of the brain addicted to food, gambling, tobacco, and opiates.

  • Cardiovascular Diseases

    Genetic Susceptibility, Environmental Factors and their Interaction
    • 1st Edition
    • Nikolaos Papageorgiou
    • English
    Cardiovascular Diseases: Genetic Susceptibility, Environmental Factors and Their Interaction covers the special heritability characteristics and identifying genetic and environmental contributions to cardiovascular health. This important reference provides an overview of the genetic basis of cardiovascular disease and its risk factors. Included are important topics, ranging from lifestyle choices, risk factors, and exposure, to pollutants and chemicals. Also covered are the influences of Mendelian traits and familial aggregation and the interactions and interrelationships between genetics and environmental factors which, when compared, provide a sound understanding of the interplay between inherited and acquired risk factors. The book provides a much needed reference for this rapidly growing field of study. By combining the latest research within the structured chapters of this reference, a better understanding of genetic and environmental contribution to cardiovascular disease is found, helping to substantiate further investigations in the field and design prevention and treatment strategies.

  • Genetics, Genomics and Fish Phenomics

    • 1st Edition
    • Volume 95
    • English
    Genetics, Genomics and Fish Phenomics provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of genetics. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions, with hhis volume focusing on genetics, genomics, and phenomics of fish.

  • Computational Approaches for Studying Enzyme Mechanism Part A

    • 1st Edition
    • Volume 577
    • English
    Computational Approaches for Studying Enzyme Mechanism Part A, is the first of two volumes in the Methods in Enzymology series, focusses on computational approaches for studying enzyme mechanism. The serial achieves the critically acclaimed gold standard of laboratory practices and remains one of the most highly respected publications in the molecular biosciences. Each volume is eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 550 volumes, the series remains a prominent and essential publication for researchers in all fields of life sciences and biotechnology, including biochemistry, chemical biology, microbiology, synthetic biology, cancer research, and genetics to name a few.

  • The Molecular and Hormonal Basis of Plant-Growth Regulation

    • 1st Edition
    • Ya' Acov Leshem
    • English
    The Molecular and Hormonal Basis of Plant-Growth Regulation deals with the molecular and hormonal basis of plant-growth regulation. Topics covered range from molecular biology in plants to the structural units of DNA, DNA replication and RNA transcription, and the process of translation and protein synthesis. The use of RNA for transmission of genetic information is also discussed. This book is comprised of 16 chapters and begins with an overview of the foundations that form the basis of modern biology, followed by an analysis of DNA and its structural units. The role of enzymes in DNA replication is then examined, together with RNA transcription and protein synthesis. The next section focuses on modern aspects of hormone action and introduces the reader to the growth-regulatory hormones existing in most higher plants; the role of ribosomes in the polymerization of transfer RNA-borne amino acids; the structure and biophysical properties of the mitochondrion and the chloroplast as genetic units; and the use of antibiotics in the inhibition of synthesis of nucleic acids and proteins. This monograph will be a valuable resource for biologists, plant physiologists, teachers, and students who seek to widen their general knowledge about plant growth.

  • Computational Approaches for Studying Enzyme Mechanism Part B

    • 1st Edition
    • Volume 578
    • English
    Computational Approaches for Studying Enzyme Mechanism, Part B is the first of two volumes in the Methods in Enzymology series that focuses on computational approaches for studying enzyme mechanism. The serial achieves the critically acclaimed gold standard of laboratory practices and remains one of the most highly respected publications in the molecular biosciences. Each volume is eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 550 volumes, the series remains a prominent and essential publication for researchers in all fields of the life sciences and biotechnology, including biochemistry, chemical biology, microbiology, synthetic biology, cancer research, genetics, and other fields of study.

  • International Review of Cell and Molecular Biology

    • 1st Edition
    • Volume 326
    • English
    International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. The series has a worldwide readership, maintaining its high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists.

  • Biomarkers in Alzheimer's Disease

    • 1st Edition
    • Tapan Khan
    • English
    Biomarkers in Alzheimer’s Disease provides a comprehensive overview of all modalities of Alzheimer’s disease biomarkers, including neuroimaging, cerebrospinal fluid, genomic, and peripheral systems. Each chapter integrates molecular/cellular abnormality due to Alzheimer’s disease and technological advancement of biomarkers techniques.The book is ideal for clinical neuroscience and molecular/cellular neuroscience researchers, psychiatrists, and allied healthcare practitioners involved in the diagnosis and management of patients with cognitive impairment and Alzheimer’s disease, and for differential diagnosis of Alzheimer’s disease with other non-Alzheimer’s dementia.

  • Host-Microbe Interactions

    • 1st Edition
    • Volume 142
    • English
    Host-Microbe Interactions, the latest volume in the Progress in Molecular Biology series, provides a forum for the discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their respective fields, along with abundant references. This volume is dedicated to the subject of host-microbe interactions.

  • New and Future Developments in Microbial Biotechnology and Bioengineering

    Aspergillus System Properties and Applications
    • 1st Edition
    • Vijai Kumar Gupta
    • English
    New and Future Developments in Microbial Biotechnology and Bioengineering: Aspergillus System Properties and Applications provides information on emerging issues related to recent advancements in aspergillus research and its applications in bioprocess technology, chemical engineering, genome biology, molecular taxonomy, secondary and metabolite production, industrial process and biofuels/bioenergy research, and alternative fuel development. The book covers the various novel enzymes secreted by these fungi and their specific use in the food, textile, pulp and paper, biocellulosic ethanol production, and other industries. The book describes research and experimentation on aspergillus activity and directly connects them to their use in bioprocess technology, chemical engineering, bioremediation process, secondary metabolite production, pharmaceutical processes, protein production, industrial process, biofuels/bioenergy research, and alternative fuel development. Readers will find this book to be an indispensable resource for biotechnologists, biochemical engineers, biochemists, microbiologists, bioinformatics researchers, and other biologists who are interested in learning about the potential applications of these fungi.

  • New and Future Developments in Microbial Biotechnology and Bioengineering

    Microbial Cellulase System Properties and Applications
    • 1st Edition
    • Vijai G. Gupta
    • English
    New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Cellulase System Properties and Applications covers the biochemistry of cellulase system, its mechanisms of action, and its industrial applications. Research has shed new light on the mechanisms of microbial cellulase production and has led to the development of technologies for production and applications of cellulose degrading enzymes. The biological aspects of processing of cellulosic biomass have become the crux of future research involving cellulases and cellulolytic microorganisms, as they are being commercially produced by several industries globally and are widely being used in food, animal feed, fermentation, agriculture, pulp and paper, and textile applications. The book discusses modern biotechnology tools, especially in the area of microbial genetics, novel enzymes, and new enzyme and the applications in various industries. As a professional reference, this new book is useful to all researchers working with microbial cellulase system, both academic institutions and industry-based research bodies, as well as to teachers, graduate, and postgraduate students with information on continuous developments in microbial cellulase system. The book provides an indispensable reference source for chemists, biochemical engineers/bioenginee... biochemists, biotechnologists and researchers who want to know about the unique properties of this microbe and explore its future applications.

  • Biotic Stress Resistance in Millets

    • 1st Edition
    • I. K. Das + 1 more
    • English
    Biotic Stress Resistance in Millets presents an important guide to the disease and pest-related challenges of this vital food crop. Biotic stresses are one of the major constraints for millet production, but newly emerging and forward-thinking problems with disease and insect pests are likely to increase as a result of changing weather, making this an imperative book on best practices. Current strategies are mainly through the development of resistant cultivars, as the use of chemicals is cost-prohibitive to many of those producing millet in developing countries where it is of most value as a food source. This book explores non-chemical focused options for improving plant resistance and protecting crop yield. This single-volume reference will be important for researchers, teachers and students in the disciplines of Agricultural Entomology, Plant protection, Resistance Plant Breeding and Biotechnological pest management.

  • The Challenge of Change

    Report of a Conference on Technological Change and Human Development at Jerusalem, 1969
    • 1st Edition
    • Trevor Evans
    • English
    The Challenge of Change: Report of a Conference on Technological Change and Human Development at Jerusalem, 1969 focuses on the relationship of the advance of technology and human development. The manuscript first offers information on the need to find a working relationship between human development and the advance of technology. The necessity for human to assert intellectual ability to retain mastery and control of technology is underscored. The text then reiterates that man should prepare to be able to cope with the advance of technology. The expansion of the capabilities of computers and their growing use are noted. The book points at the role of education in helping human to be able to adjust to technological changes, as well as the vital influence of modern technology in raising the economic standards of less developed countries. The text also underscores the need for workers to have a greater share in the ownership of capital. The issue of unequal distribution of wealth and the effects of automation in labor practices are discussed. The manuscript is a dependable source of information for readers interested in establishing the relationship of technological advancement and human development.

  • Advances in Agronomy

    • 1st Edition
    • Volume 139
    • English
    Advances in Agronomy continues its reputation as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. Five volumes are published yearly, ensuring that the authors’ contributions are disseminated to the readership in a timely manner. As always, the subjects covered are varied and exemplary of the myriad of subject matter dealt with by this long-running serial.

  • Schering Symposium on Endocrinology, Berlin, May 26 to 27, 1967

    Advances in the Biosciences
    • 1st Edition
    • G. Raspé
    • English
    Advances in the Biosciences 1: Schering Symposium on Endocrinology, Berlin, May 26 to 27, 1967 is a collection of papers presented at the Schering Symposium on Endocrinology held in Berlin, Germany, on May 26-27, 1967. Contributors explore a wide range of topics relating to endocrinology, including the radioimmunoassay of gonadotropins; steroid transformations in human and rat testes; hormonal control of sexual behavior in adult rats; and regulation of synthesis and release of anterior pituitary hormones both in vitro and in vivo. This book is comprised of 25 chapters and begins by analyzing a hormone, prepared from liquor folliculi and whole ovaries, that causes typical estrus in spayed rats, followed by a discussion on the preparation of a crystalline ovarian hormone from the urine of pregnant women. Subsequent chapters focus on hypothalamic control and pathways of release of neurohypophysial hormones; effect of amino acids and proteins on insulin secretion in human subjects; hormonal regulation of sexual behavior in adult rats; and some aspects of steroid transformations in the testes of human subjects and of rats with experimental cryptorchidism or feminization. Results of ultrastructural and subcellular studies of storage and release of neurohypophysial hormones are also presented. This monograph will be a useful resource for endocrinologists.

  • The Evaluation of Toxicological Data for the Protection of Public Health

    Proceedings of the International Colloquium, Luxembourg, December 1976
    • 1st Edition
    • W. J. Hunter + 1 more
    • English
    The Evaluation of Toxicological Data for the Protection of Public Health: Proceedings of the International Colloquium, Luxembourg, December 1976 focuses on the review of toxicological tests and methods used in toxicological evaluation of chemicals and reconsideration of these procedures in identifying decision-making processes involved in the protection of public health. The selection first discusses reviews of toxicological tests, including introductory remarks and comments on acute toxicity; problems associated with the testing of environmental mutagens; and the testing of carcinogenic potentials. The publication also examines the uncertainties related to the evaluation of the health hazards of environmental chemicals from toxicological data and epidemiological monitoring of indices of chemical hazards. The book takes a look at safety factors and their application in toxicological evaluation; ecotoxicological approaches for the protection of environment and health; and use of biological materials as environmental pollution gauges. The text also discusses acute toxicity, teratogenic effects of pollutants, and examples of ecotoxicological research. The selection is a dependable source of data for readers interested in the evaluation of toxicological data relative to the protection of public health.

  • Investigating the Life Sciences

    An Introduction to the Philosophy of Science
    • 1st Edition
    • G. M. N. Verschuuren
    • English
    A unique introduction to the philosophy of science with special emphasis on the life sciences. Part I presents elementary but fundamental concepts and problems in epistemology and their relation to questions of scientific methodology. Part II deals with case studies from the history of biology which illustrate particular philosophical points while Part III progresses to more complex ideas as on the nature and methodology of science. Part IV discusses the limitations of scientific enquiry and its relations to other systems of knowledge and interpretation.

  • Principles of X-Ray Diagnosis

    • 1st Edition
    • David H. Trapnell
    • English
    Principles of X-Ray Diagnosis covers the system of observation and deductions of a radiologist taken from radiographs. This book is composed of 12 chapters that discuss the principles of diagnostic radiology and the methods of producing radiographs. Some of the topics covered in the book are the production of X-rays; formation of radiographic image; application and definition of fluorescence; intensification of an image; determining the quality of a radiograph; practical problems of radiography; preparing a radiograph; analysing defects in radiographs; and factors affecting film quality. Other chapters provide the method of determining lesion site and the detection and significance of fluid levels. These topics are followed by descriptions of the characteristics and assessment of chest radiographs. The final chapter is devoted to the normal radiographic anatomy of the heart. The book can provide useful information to the radiologists, doctors, students, and researchers.

  • Biosensors 92 Proceedings

    The Second World Congress on Biosensors
    • 1st Edition
    • W.R. Heineman + 3 more
    • English
    Keeping up to date with new biosensors developments has been getting harder ...– one of the fastest moving fields of academic and industrial research in the world– a constant stream of new commercial applications– centres of research excellence all over Europe, North America and the Pacific Rim– enormous implications for monitoring personal health and fitness, the food we eat, the environment, health services and industryThe answer came on 20–22 May 1992, with BIOSENSORS 92. With a core of invited speakers and over 220 original contributed papers from 24 countries, BIOSENSORS 92 was the largest and most comprehensive event of its kind – a response to the growing importance of biosensors as a powerful new technology.Elsevier Advanced Technology, the organizers of BIOSENSORS 92, have now published the proceedings of this important event.Biosensors 92 Proceedings contains over 150 papers presenting current research and developments straight from those who are leading the way in:– Enzyme–based Sensors– Affinity Sensors– Environmental Monitoring using Biosensors– Biosensors and BioelectronicsBiosen... 92 Proceedings – Your key to current awareness in sensor technology for just £90 [dollar rate subject to current £/$ exchange rate].

  • Recent Advances in Animal Nutrition

    • 1st Edition
    • W. Haresign
    • D.J.A. Cole + 2 more
    • English
    Recent Advances in Animal Nutrition — 1982 focuses on the compositions of animal feeds. The book first discusses the presence of molds and mycotoxins in animal feeds. Controlling mycotoxin exposure, formation and effects of mycotoxins, and microbiology of feeds are described. The text surveys the anti-nutritive factors in animal feeds. Substances depressing digestion or metabolic utilization of proteins; substances reducing the solubility or interfering with the utilization of mineral elements; and substances inactivating or increasing the requirements of vitamins are discussed. The book also highlights oilseed meals for livestock feeding; the use of databases for the composition and nutritive value of animal feeds; and energy evaluation of poultry rations. The text underscores the influence of nutrition on hatchability, including the composition and size of hatching eggs; the right amounts of proteins, lipids, vitamins, and minerals; feed ingredients; and feeding practices. The book also discusses the energy and protein requirements of pigs and methods used in the analysis of the energy content of ruminant feeds. The selection is a good source of data for readers interested in studying the compositions of animal feeds.

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