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Books in Life sciences

  • Advances in the Study of Behavior

    • 1st Edition
    • Volume 49
    • Marc Naguib
    • English
    Advances in the Study of Behavior, Volume 49 provides users with the latest insights in this ever-evolving field. Users will find new information on a variety of species, including social behaviors in reptiles, the behavioral evidence of felt emotions, a section on developmental plasticity, a chapter on covetable corpses and plastic beetles and the socioecological behavior of burying beetles, and a section on the mechanisms of communication and cognition in chickadees. This volume makes another important contribution to the development of the field by presenting theoretical ideas and research findings to professionals studying animal behavior and related fields. Researchers in a variety of behavioral fields will find this longstanding series, initiated over 40 years ago, to be a go-to resource for the study of animal behavior.
  • How to Optimize Fluid Bed Processing Technology

    Part of the Expertise in Pharmaceutical Process Technology Series
    • 1st Edition
    • Dilip Parikh
    • English
    How to Optimize Fluid Bed Processing Technology: Part of the Expertise in Pharmaceutical Process Technology Series addresses the important components of fluid bed granulation, providing answers to problems that commonly arise and using numerous practical examples and case studies as reference. This book covers the theoretical concepts involved in fluidization, also providing a description of the choice and functionality of equipment. Additional chapters feature key aspects of the technology, including formulation requirements, process variables, process scale-up, troubleshooting, new development, safety, and process evaluation. Given its discussion of theoretical principles and practical solutions, this is a go-to resource for all those scientists and new researchers working with fluid bed granulation as a unit operation.
  • Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

    • 1st Edition
    • Surendra Nimesh + 2 more
    • English
    Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc.
  • Proteomics in Food Science

    From Farm to Fork
    • 1st Edition
    • Michelle Lisa Colgrave
    • English
    Proteomics in Food Science: From Farm to Fork is a solid reference providing concepts and practical applications of proteomics for those in various disciplines of food science. The book covers a range of methods for elucidating the identity or composition of specific proteins in foods or cells related to food science, from spoilage organisms, to edible components. A variety of analytical platforms are described, ranging from the usage of simple electrophoresis, to more sophisticated mass spectrometry and bio-informatic platforms. The book is designed for food scientists, technologists, food industry workers, microbiologists, and public health workers, and can also be a valuable reference book for students.
  • Antimicrobial Stewardship

    • 1st Edition
    • Volume 2
    • Céline Pulcini + 3 more
    • English
    Antimicrobial Stewardship (AMS), Volume Two includes the experience of ESGAP workshops and courses on antibiotic stewardship since 2012. It combines clinical and laboratory information about AMS, with a focus on human medicine. The ESCMID study group on antibiotic policies (ESGAP) is one of the most productive groups in the field, organizing courses and workshops. This book is an ideal tool for the participants of these workshops. With short chapters (around 1500 words) written on different topics, the authors insisted on the following points: A ‘hands on’, practical approach, tips to increase success, a description of the most common mistakes, a global picture (out- and inpatient settings, all countries) and a short list of 10-20 landmark references.
  • Nanoencapsulation Technologies for the Food and Nutraceutical Industries

    • 1st Edition
    • Seid Mahdi Jafari
    • English
    Nanoencapsulation Technologies for the Food and Nutraceutical Industries is a compendium which collects, in an easy and compact way, state-of-the-art details on techniques for nanoencapsulation of bioactive compounds in food and nutraceutical industries. The book addresses important modern technologies, including biopolymer based nano-particle formation techniques, formulation based processes, such as nano-liposomes and nano-emulsions, process based nano-encapsulation, such as electro-spinning and nano-spray drying, natural nano-carrier based processes, like casein and starch nano-particles, and other recent advances. This definitive reference manual is ideal for researchers and industry personnel who want to learn more about basic concepts and recent developments in nanotechnology research.
  • Carcinogenesis

    Proceedings of a Symposium on the Biology of Skin Held at the University of Oregon Medical School, 1965
    • 1st Edition
    • William Montagna + 1 more
    • English
    Advances in Biology of Skin, Volume VII: Carcinogenesis covers proceedings of the 15th Symposium on the Biology of Skin, held at the Oregon Regional Primate Research Center on April 9-11, 1965, under the auspices of the University of Oregon Medical School. This book is composed of nineteen chapters, and begins with the mechanism of tissue homeostasis in adult mammals and the kinetics of epidermal reaction to carcinogenic agents and other skin irritants. The succeeding chapters deal with the growth promoting effects of tumors on tissues, the reaction pattern distinctions between normal and neoplastic epithelium, and some biological implications of chemical carcinogenesis. Considerable chapters are devoted to various carcinogens, including hydrocarbons, viruses, androgens, and estrogens. Other chapters consider the physicochemical mechanisms of acceleration of skin carcinogenesis and experimental observations of environmental carcinogenesis. The mechanisms of skin cancer induction due to ultraviolet radiation, as well as arsenic induced tumors are examined. The concluding chapters describe some forms of skin tumors, such as adnexal tumors and basal cell epithelioma. This book will prove useful to oncologists and researchers in the field of carcinogenesis.
  • Microbial Resources

    From Functional Existence in Nature to Applications
    • 1st Edition
    • Ipek Kurtboke
    • English
    Microbial Resources: From Functional Existence in Nature to Applications provides an exciting interdisciplinary journey through the rapidly developing field of microbial resources, including relationships to aspects of microbiology. Covers the functional existence of microorganisms in nature, as well as the transfer of this knowledge for industrial and other applications. Examines the economic perspective of revealing the potential value of microbial material and figuring it into socio-economic value; legal perspectives; and how to organize a fair allotment of socio-economic benefits to all stakeholders who have effectively contributed to the preservation, study, and exploitation of microbiological material.
  • Disease-Modifying Targets in Neurodegenerative Disorders

    Paving the Way for Disease-Modifying Therapies
    • 1st Edition
    • Veerle Baekelandt + 1 more
    • English
    Disease-Modifying Targets in Neurodegenerative Disorders: Paving the Way for Disease-Modifying Therapies examines specific neurodegenerative disorders in comprehensive chapters written by experts in the respective fields. Each chapter contains a summary of the disease management field, subsequently elaborating on the molecular mechanisms and promising new targets for disease-modifying therapies. This overview is ideal for neuroscientists, biomedical researchers, medical doctors, and caregivers, not only providing readers with a summary of the way patients are treated today, but also offering a glance at the future of neurodegenerative disorder treatment.
  • Basic Science Methods for Clinical Researchers

    • 1st Edition
    • Morteza Jalali + 2 more
    • English
    Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow’s clinician scientists and future leaders in discovery science.
  • Thyroid Cancer and Nuclear Accidents

    Long-Term Aftereffects of Chernobyl and Fukushima
    • 1st Edition
    • Shunichi Yamashita + 1 more
    • English
    Thyroid Cancer and Nuclear Accidents: Long-Term Aftereffects of Chernobyl and Fukushima discusses the radiobiological effects of the release of radioiodine from two nuclear power plant accidents and appropriate interpretation of the results of thyroid ultrasound examination. The book pulls together expert opinion on radiation related thyroid cancer in an understandable manner, even for non thyroidologists. The book explains what has been learned from both accidents in relation to prevention of thyroid cancer following nuclear power plant accidents. The book encompasses topics such as risk estimations of thyroid cancer following nuclear accidents and clinical aspects after those specific situations. Additionally, it discusses in detail the reports from Fukushima related to thyroid cancer in the population. This book is a valuable resource for oncologists and biomedical researchers with interest in nuclear accidents and cancer cases.
  • Development of Biodiesel-Resistant Nitrile Rubber Compositions

    • 1st Edition
    • Felipe N. Linhares
    • English
    Biodiesel is an excellent potential replacement for petroleum diesel fuels because of its comparable physical properties in addition to its improved environmental benefits, such as low pollutant gas emissions, nontoxicity, renewability, and biodegradability. However, biodiesel and petroleum diesel differ greatly with respect to their chemical properties. Therefore, the compatibility of the materials that are commonly employed in contact with diesel must also be assured for biodiesel that has been obtained from different sources. Although nitrile rubber (NBR) has previously not been recommended for biodiesel applications, up to now no effort has been made to better understand the interaction between nitrile rubber and biodiesel or to propose improvements to the production of NBR articles. This book evaluates the resistance of different types of NBR and NBR formulations to biodiesel.It is shown how increasing acrylonitrile content and carboxylation increase the rubber resistance to biodiesel, and a new method employing accelerators to prepare novel biodiesel-resistant formulations is described. The choice of accelerator has a significant effect on the biodiesel resistance, and compositions prepared from an efficient vulcanization system are shown to be most resistant to chemical degradation. The effects on physical properties such as tensile strength, hardness, and elongation at break are also analyzed and evaluated. The potential for these materials to be used in applications in which they will be in contact with biodiesel is thus demonstrated.
  • Practical Stress Management

    A Comprehensive Workbook
    • 7th Edition
    • John A. Romas + 1 more
    • English
    Practical Stress Management: A Comprehensive Workbook, Seventh Edition, is a focused, personal, worksheet-based text that combines theory and principles with hands-on exercises to help readers manage the negative impact of stress in life. As a practical tool for recognizing and preventing stress, the action-oriented approach enables the student to make personal change through self-reflection and behavior change techniques. This approach allows the book to be used as a text in a course or as a self-study/reference book. In this edition, the authors cover financial stress and expand their section on sleep. The book is accompanied by online MP3 files of guided relaxation techniques and downloadable worksheets. In addition, worksheets and thoughts for reflection boxes help users determine their own level of stress and apply effective stress management techniques.
  • Nano- and Microscale Drug Delivery Systems

    Design and Fabrication
    • 1st Edition
    • Alexandru Mihai Grumezescu
    • English
    Nano- and Microscale Drug Delivery Systems: Design and Fabrication presents the developments that have taken place in recent years in the field of micro- and nanoscale drug delivery systems. Particular attention is assigned to the fabrication and design of drug delivery systems in order to i) reduce the side effects of therapeutic agents, ii) increase their pharmacological effect, and iii) improve aqueous solubility and chemical stability of different therapeutic agents. This book is designed to offer a cogent, concise overview of current scholarship in this important area of research through its focus on the characterization and fabrication of a variety of nanomaterials for drug delivery applications. It is an invaluable reference source for both biomaterials scientists and biomedical engineers who want to learn more about how nanomaterials are engineered and used in the design of drug delivery nanosystems.
  • Handbook of Grape Processing By-Products

    Sustainable Solutions
    • 1st Edition
    • Charis M. Galanakis
    • English
    Handbook of Grape Processing By-Products explores the alternatives of upgrading production by-products, also denoting their industrial potential, commercial applications and sustainable solutions in the field of grape valorization and sustainable management in the wine industry. Covering the 12 top trending topics of winery sustainable management, emphasis is given to the current advisable practices in the field, general valorization techniques of grape processing by-products (e.g. vermi-composting, pyrolysis, re-utilization for agricultural purposes etc.), the newly introduced biorefinery concept, different techniques for the separation, extraction, recovery and formulation of polyphenols, and finally, the healthy components of grape by-products that lead to target applications in the pharmaceutical, enological, food and cosmetic sectors.
  • Reproductive and Developmental Toxicology

    • 2nd Edition
    • Ramesh C. Gupta
    • English
    Reproductive and Developmental Toxicology, Second Edition, is a comprehensive and authoritative resource that provides the latest literature on this complex subject with a primary focus on three core components—parent, placenta, and fetus—and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics, including nanoparticles and radiation, gases and solvents, smoking, alcohol and drug abuse, and metals, amongst others. With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages, also including discussions on reproductive and developmental toxicity in domestic animals, fish, and wildlife. Completely revised and updated to include the most recent developments in the field, the book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists, and teratologists from academia, industry, and regulatory agencies.
  • Nanostructures for Drug Delivery

    • 1st Edition
    • Ecaterina Andronescu + 1 more
    • English
    Nanostructures for Drug Delivery extensively covers the various nanostructured products that have been tested as carriers in target drug delivery systems. In addition, the book analyses the advantages of, and issues related to, using nanostructured materials in drug delivery systems, also detailing various nanocarrier preparation techniques. As delivering the drug to the target site is a major problem in providing effective treatment for many diseases, this book covers the latest advancements in numerous nanotechnological products that are being used in disease detection, controlled drug delivery, as biosensors, and in tissue engineering that have been developed for more efficient patient healthcare. Due to the versatility of nanostructured materials, it is now possible to deliver a drug at its target site in a more accurate and efficient way. This volume is an up-to-date, state-of-the-art work that highlights the principal mechanistic aspects related to the delivery of active nanoscale therapeutic agents (natural or synthetic) and their release profile in different environmental media. It highlights nanoscale encapsulation strategies and discusses both organic and inorganic nanomaterials as carriers and delivery platforms.
  • Essentials of Neuroanesthesia

    • 1st Edition
    • Hemanshu Prabhakar
    • English
    Essentials of Neuroanesthesia offers useful insights on the anesthetic management of neurosurgical and neurologic patients. This book covers all topics related to neuroanesthesia, providing essential knowledge on the brain and spinal cord. Sections include chapters on anatomy, physiology, and pharmacology, along with specific chapters related to various neurosurgical and neurological problems and their anesthetic management. This book provides an understanding of related issues, such as palliative care, evidence based practice of neuroanesthesia, sterilization techniques, biostatistics, and ethical issues, and is useful for trainees, clinicians, and researchers in the fields of neurosurgery, neurocritical care, neuroanesthesia, and neurology.
  • Genomic and Precision Medicine

    Primary Care
    • 3rd Edition
    • Geoffrey S. Ginsburg + 2 more
    • English
    Genomic and Precision Medicine: Primary Care, Third Edition is an invaluable resource on the state-of-the-art tools, technologies and policy issues that are required to fully realize personalized health care in the area of primary care. One of the major areas where genomic and personalized medicine is most active is the realm of the primary care practitioner. Risk, family history, personal genomics and pharmacogenomics are becoming increasingly important to the PCP and their patients, and this book discusses the implications as they relate to primary care practitioners.
  • New Aspects of Meat Quality

    From Genes to Ethics
    • 1st Edition
    • Peter P. Purslow
    • English
    New Aspects of Meat Quality: From Genes to Ethics provides a reference source that covers what constitutes meat quality in the minds of consumers, marketers, and producers in the 21st century, using the same scientific authority as texts on traditional meat quality values. Traditional measures in meat quality, such as texture, waterholding, color, flavor/aroma, safety/microbiology, and processing characteristics are still important, however, additional quality attributes now have huge importance in the purchasing intentions of consumers in many countries. These include, amongst others, animal welfare, the impacts of meat on human health, quality assurance schemes, organic/free range, ethical meat production, and the desirability of genetically modified organisms. The book is divided into three main sections, with the first section covering the developments in our understanding of how muscle structure affects the eating qualities of cooked meat. The second section highlights recently developed techniques for measuring, predicting, and producing meat quality, and how these new techniques help us minimize variability in eating quality and/or maximize value. The final section identifies the current qualities of consumer and public perceptions, and what is sustainable, ethical, desirable, and healthy in meat production and consumption.
  • Existence Theory for Generalized Newtonian Fluids

    • 1st Edition
    • Dominic Breit
    • English
    Existence Theory for Generalized Newtonian Fluids provides a rigorous mathematical treatment of the existence of weak solutions to generalized Navier-Stokes equations modeling Non-Newtonian fluid flows. The book presents classical results, developments over the last 50 years of research, and recent results with proofs.
  • Biology and Engineering of Stem Cell Niches

    • 1st Edition
    • Ajaykumar Vishwakarma + 1 more
    • English
    Biology and Engineering of Stem Cell Niches covers a wide spectrum of research and current knowledge on embryonic and adult stem cell niches, focusing on the understanding of stem cell niche molecules and signaling mechanisms, including cell-cell/cell-matri... interactions. The book comprehensively reviews factors regulating stem cell behavior and the corresponding approaches for understanding the subsequent effect of providing the proper matrix molecules, mechanical cues, and/or chemical cues. It encompasses a variety of tools and techniques for developing biomaterials-based methods to model synthetic stem cell niches in vivo, or to enhance and direct stem cell fate in vitro. A final section of the book discusses stem cell niche bioengineering strategies and current advances in each tissue type.
  • Enzymes as Sensors

    • 1st Edition
    • Volume 589
    • English
    Enzymes as Sensors, Volume 589, the latest release in the Methods in Enzymology series, covers a variety of topics, including advances in genetically coded fluorescent sensors, enzymes as sensors, and bioapplications of electrochemical sensors and biosensors. Users will find a comprehensive discussion of timely topics that presents a micro-level delivery of specific content related to the study of enzymes in sensors. New to this edition are highly specialized chapters on integrated strategies for gaining a systems level view of dynamic signaling networks, sensitive protein detection and quantification in paper-based microfluidics for point-of-care, and microneedle enzyme sensor arrays for continuous in vivo monitoring. This state-of-the-art series is ideal for those interested in the latest information on enzymology, with this edition focusing on sensors and their role in enzymes.
  • Zebrafish at the Interface of Development and Disease Research

    • 1st Edition
    • Volume 124
    • English
    Zebrafish at the Interface of Development and Disease Research presents the latest on the shared pathways that govern development and contribute to disease. Zebrafish have traditionally been used to study vertebrate development, providing interesting data on the developmental processes and genes that are implicated in disease. This new release in the series contains informative discussions on congenital heart defects in zebrafish, the use of zebrafish in studying kidney development and disease, and muscle development, homeostasis and disease in zebrafish. Each chapter interweaves the study of zebrafish development and its application to the immune system, the kidney, liver, heart and others.
  • Lifestyle Medicine

    Lifestyle, the Environment and Preventive Medicine in Health and Disease
    • 3rd Edition
    • Michael Sagner + 3 more
    • English
    Lifestyle Medicine: Lifestyle, the Environment and Preventive Medicine in Health and Disease, Third Edition, is an adjunct approach to health practice that seeks to deal with the more complex modern determinants of chronic diseases—primarily lifestyle and the environments driving such lifestyles—in contrast to the microbial ‘causes’ of infectious disease. Our lifestyle choices have a profound effect on our health. As we live longer, one thing is clear: many of us will spend time living with injury and chronic illness due to our own choices. Changes in health patterns typically follow shifts in living conditions. Disease patterns have changed worldwide, from infectious to chronic diseases such as obesity, diabetes, and heart disease. This change has been so emphatic—nearly 70% of all presentations to a doctor in modern western societies are now chronic disease related—that medical services are being forced to change to accommodate this. New chapters in this third edition explain the link between energy intake and expenditure; consider how modern technology are determinants of chronic disease; show how environmental influences, such as endocrine disruptors, influence our health; and summarize recent research on early childhood experiences and chronic disease.
  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 25
    • English
    Advances in Biomembranes and Lipid Self-Assembly, formerly titled Advances in Planar Lipid Bilayers and Liposomes, provides a global platform for a broad community of experimental and theoretical researchers studying cell membranes, lipid model membranes, and lipid self-assemblies from the micro- to the nanoscale. Planar lipid bilayers are widely studied due to their ubiquity in nature, also finding application in the formulation of biomimetic model membranes. Section topics in this release cover Ras Proteolipid nano-assemblies on the plasma membrane, gold nanomaterials, recent advances in cancer theranostics, and the interactions of flavonoids with lipidic mesophases, amongst other highly resourceful topics. Self-assembled lipid structures have enormous potential as dynamic materials, ranging from artificial lipid membranes, to cell membranes, from biosensing, to controlled drug delivery, and from pharmaceutical formulations, to novel food products, to name a few. This series represents both original research and comprehensive reviews written by world-leading experts and young researchers.
  • Advances in Parasitology

    • 1st Edition
    • Volume 97
    • English
    Advances in Parasitology presents the latest developments in the field of parasitology. It covers topics such as Chagas Disease Diagnostic Applications, The Role of Spatial Statistics in the Control and Elimination of Neglected Tropical Diseases in Sub-Saharan Africa, and Host–Parasite Relationships and Life Histories of Trypanosomes in Australia. Specific chapters delve into targeting parasites to suppress malaria transmission and a focus on neglected tropical diseases, such as Trypanosomiasis, Schistosomiasis and Lymphatic Filariasis. This series includes medical studies of parasites of major influence, such as Plasmodium falciparum and trypanosomes, as well as reviews of more traditional areas, such as zoology, taxonomy and life history.
  • How Plants Communicate with their Biotic Environment

    • 1st Edition
    • Volume 82
    • Guillaume Becard
    • English
    How Plants Communicate with Their Biotic Environment addresses how plants perceive the presence of organisms (other plants, microbes, insects and nematodes) living in their proximity, how they manage to be attractive when these organisms are friendly, and how they defend themselves from foes. Specific chapters delve into ecology and defense mechanisms, allelopathy and the role of allelochemicals in plant defense, plant signaling, and plant communication with microbes and animals, including herbivores. In addition, the book presents discussions on communication and its role in plant pollination. This comprehensive resource presents tactics that can be taken from the lab, to the bench, to the forest.
  • Nitric Oxide Donors

    Novel Biomedical Applications and Perspectives
    • 1st Edition
    • Amedea Seabra
    • English
    Nitric Oxide Donors: Biomedical Applications and Perspectives presents the current state of art, challenges and innovations in the design of therapeutics nitric oxide donors with great impact in several aspects of human physiology and pathophysiology. Although considerable innovative progress has been achieved using Nitric Oxide donors in biomedical applications, certain drawbacks still need to be overcome to successfully translate these research innovations into clinical applications. This book encompasses several topics on nitric oxide such as its sources and biological properties; its performance in the cardiovascular and neurologic systems, in the human skin and its application in the treatment of neglected diseases, neurodegenerative disorders, and cancer. Additionally, it covers its role in inflammation and immunity, penile erection function, photodynamic therapy, antimicrobial activities. It also discusses the future of nitric oxide donors in combination with other therapeutic drugs, in implantable sensors, and nitric oxide releasing hydrogels and medical devices for topical applications. The book is a valuable source for researchers on different areas of biomedical field who are interested in the improvements that these molecules can make in the treatment of several conditions.
  • Japanese Kampo Medicines for the Treatment of Common Diseases

    Focus on Inflammation
    • 1st Edition
    • Somasundaram Arumugam + 1 more
    • English
    Japanese Kampo Medicines for the Treatment of Common Diseases - Focus on Inflammation provides researchers and clinicians with a current look at how Kampo medicines can be used to effectively treat inflammatory disorders. Japanese Kampo medicines are a mixture of natural and herbal medicines that are available in Japan for the treatment of various diseases. Given their therapeutic potential, they are often prescribed instead of, or alongside, allopathic medicines.Kampo medicines are becoming more widespread and have proven effective for the treatment of a variety of inflammatory diseases, such as colitis, dermatitis, myocarditis, hepatitis, cardiomyopathy, and nephritis. This book offers background on Japanese Kampo medicines, along with a compilation of the published scientific data for several different types of Kampo medicines. It is an evidence-based guide for all those involved in, or interested in, the research and practice of Kampo medicine.
  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 81
    • English
    Advances in Food and Nutrition Research, Volume 81 provides updated knowledge on nutrients in foods and how to avoid deficiencies, paying special attention to the essential nutrients that should be present in the diet to reduce disease risk and optimize health. This new release in the series focuses on a variety of topics, including sections on nanotechnologies that can be used to increase nutrient bioavailability, an analysis of the implications of nitrites and nitrates in foods, metabolic phenotyping of diet and dietary intake, and an interesting discussion of foodomics, amongst other topics. The series provides the latest advances on the identification and characterization of emerging bioactive compounds with putative health benefits, as well as up-to-date information on food science, including raw materials, production, processing, distribution and consumption.
  • Soil Health and Intensification of Agroecosystems

    • 1st Edition
    • Mahdi M. Al-Kaisi + 1 more
    • English
    Soil Health and Intensification of Agroecosystems examines the climate, environmental, and human effects on agroecosystems and how the existing paradigms must be revised in order to establish sustainable production. The increased demand for food and fuel exerts tremendous stress on all aspects of natural resources and the environment to satisfy an ever increasing world population, which includes the use of agriculture products for energy and other uses in addition to human and animal food. The book presents options for ecological systems that mimic the natural diversity of the ecosystem and can have significant effect as the world faces a rapidly changing and volatile climate. The book explores the introduction of sustainable agroecosystems that promote biodiversity, sustain soil health, and enhance food production as ways to help mitigate some of these adverse effects. New agroecosystems will help define a resilient system that can potentially absorb some of the extreme shifts in climate. Changing the existing cropping system paradigm to utilize natural system attributes by promoting biodiversity within production agricultural systems, such as the integration of polycultures, will also enhance ecological resiliency and will likely increase carbon sequestration.
  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 56
    • English
    Progress in Medicinal Chemistry, Volume 56 provides a review of eclectic developments in medicinal chemistry. This volume includes chapters covering recent advances in cancer therapeutics, fluorine in medicinal chemistry, a perspective on the next generation of antibacterial agents derived by manipulation of natural products, a potential new era for Chagas Disease drug discovery, and imaging in drug development. Specific chapters cover timely topics, such as the development of LRRK2 inhibitors for the treatment of Parkinson's, and recent discoveries and developments in TRPA1 modulators. Users will find a comprehensive resource on the topic of medicinal chemistry that also discusses avenues for the acceleration of drug discovery programs.
  • International Review of Cell and Molecular Biology

    • 1st Edition
    • Volume 331
    • English
    International Review of Cell and Molecular Biology reviews and details current advances in cell and molecular biology. This most current release in this highly cited series focuses on such timely topics as novel treatments in immunotherapy in breast cancer, chemokine receptor signaling and the hallmarks of cancer, tumor-targeting antibodies, and a section on mitochondrion and whether they are a common organelle for cell death. As always, readers will find the articles in this series to be of great value, with a high impact and average cited half-life of nine years. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. This great resource ranks high amongst scientific journals dealing with cell biology.
  • Soil Mapping and Process Modeling for Sustainable Land Use Management

    • 1st Edition
    • Paulo Pereira + 3 more
    • English
    Soil Mapping and Process Modeling for Sustainable Land Use Management is the first reference to address the use of soil mapping and modeling for sustainability from both a theoretical and practical perspective. The use of more powerful statistical techniques are increasing the accuracy of maps and reducing error estimation, and this text provides the information necessary to utilize the latest techniques, as well as their importance for land use planning. Providing practical examples to help illustrate the application of soil process modeling and maps, this reference is an essential tool for professionals and students in soil science and land management who want to bridge the gap between soil modeling and sustainable land use planning.
  • Toxicology in the Middle Ages and Renaissance

    • 1st Edition
    • Philip Wexler
    • English
    Toxicology in the Middle Ages and Renaissance provides an authoritative and fascinating exploration into the use of toxins and poisons in the Middle Ages and Renaissance. Part of the History of Toxicology and Environmental Health series, this volume is a follow-up, chronologically, to the first two volumes which explored toxicology in antiquity. The book approximately covers the 1100s through the 1600s, delving into different aspects of toxicology, such as the contributions of scientific scholars of the time, sensational poisoners and poisoning cases, as well as myths. Historical figures, such as the Borgias and Catherine de Medici are discussed. Toxicologists, students, medical researchers, and those interested in the history of science will find insightful and relevant material in this volume.
  • Adenosine Receptors in Neurodegenerative Diseases

    • 1st Edition
    • David Blum + 1 more
    • English
    Adenosine Receptors in Neurodegenerative Diseases covers the role of adenosine receptors in brain function, also focusing on related methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field. Chapters include adenosine biology and signaling, gene regulation, control of motor function, and novel adenosine-based therapies in the CNS. It is an ideal resource for researchers, advanced graduate students, clinicians, and industry scientists working in the fields of clinical neuroscience and molecular and cellular neuroscience.
  • Hematopoietic Stem Cell Niche

    • 1st Edition
    • Volume 1
    • English
    Hematopoietic Stem Cell Niche focuses on an individual organ, looking at the stem cells in the organ itself (if they exist), their niches, and how to use them alongside relevant methods and protocols. This series addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments, such as new data on disease and clinical applications. Specific chapters delve into the evolution of hematopoietic stem cell niches, the role of CNS in the regulation of HSCs, and targeting the bone marrow niche in hematological malignancies. In addition, video content illustrates protocols, transplantation techniques, and work with mice.
  • Atlas of the Human Body

    Central Nervous System and Vascularization
    • 1st Edition
    • Branislav Vidic + 1 more
    • English
    Atlas of Human Body: Central Nervous System and Vascularization is a multidisciplinary approach to the technical coverage of anatomical structures and relationships. It contains surface and 3D dissection images, native and colored cross sectional views made in different planes, MRI comparisons, demonstrations of cranial nerve origins, distribution of blood vessels by dissection, and systematic presentation of arterial distribution from the precapillary level, using the methyl metacrylate injection and subsequent tissue digestion method.  Included throughout are late prenatal (fetal) and early postnatal images to contribute to a better understanding of structure/relationsh... specificity of differentiation at various developmental intervals (conduits, organs, somatic, or branchial derivatives). Each chapter features clinical correlations providing a unique perspective of side-by side comparisons of dissection images, magnetic resonance imaging and computed tomography. Created after many years of professional and scientific cooperation between the authors and their parent institutions, this important resource will serve researchers, students, and doctors in their professional work.
  • Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease

    • 1st Edition
    • Venkataramana K Sidhaye + 1 more
    • English
    Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition.
  • Applications in High Resolution Mass Spectrometry

    Food Safety and Pesticide Residue Analysis
    • 1st Edition
    • Roberto Romero-González + 1 more
    • English
    Applications of High Resolution Mass Spectrometry: Food Safety and Pesticide Residue Analysis is the first book to offer complete coverage of all aspects of high resolution mass spectrometry (HRMS) used for the analysis of pesticide residue in food. Aimed at researchers and graduate students in food safety, toxicology, and analytical chemistry, the book equips readers with foundational knowledge of HRMS, including established and state-of-the-art principles and analysis strategies. Additionally, it provides a roadmap for implementation, including discussions of the latest instrumentation and software available. Detailed coverage is given to the application of HRMS coupled to ultra high-performance liquid chromatography (UHPLC-HRMS) in the analysis of pesticide residue in fruits and vegetables and food from animal origin. The book also discusses extraction procedures and the challenges of sample preparation, gas chromatography coupled to high resolution mass spectrometry, flow injection-HRMS, ambient ionization, and identification of pesticide transformation products in food. Responding to the fast development and application of these new procedures, this book is an essential resource in the food safety field.
  • Carbon Nanomaterials for Biological and Medical Applications

    • 1st Edition
    • Sekhar Chandra Ray + 1 more
    • English
    Nanomaterials for Biological and Medical Applications explores the different applications of carbon nanomaterials in drug and gene therapies and their use in tissue regeneration, biosensor diagnosis, enantiomer separation of chiral drugs, extraction and analysis of drugs and pollutants, and as antitoxents. The book describes the synthesis processing of carbon nanomaterials, carbon composite nanomaterials, and their different biological and biomedical applications, including the removal of biologically toxic materials, optical biosensor applications, bio-imaging probe, drug delivery, cancer treatments, and other biomedical applications.
  • Liver Pathophysiology

    Therapies and Antioxidants
    • 1st Edition
    • Pablo Muriel
    • English
    Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies.
  • Glycerol

    The Renewable Platform Chemical
    • 1st Edition
    • Mario Pagliaro
    • English
    Glycerol: The Renewable Platform Chemical provides a valuable overview of the glycerol market, including industrial applications and sustainable production of glycerol. Replacing previous works on the subject, this useful resource describes glycerol, also known as glycerine, and its chemical derivatives, especially the new bioglycerol-derived products. The monograph also discusses how the industrial use of glycerol as raw material for producing commodity chemicals depends on broader scope and lower cost of the catalytic process used to convert glycerol of varying purity grades into valued monomers. New chapters on glycerol polymers, the use of glycerol as antifreeze, and its sustainable production offer relevant information for researchers and professionals from academics and industry alike. The book features new processes, such as low cost and biocompatible glycerol polymers as a major alternative to the conventional polymers, with the first practical applications now emerging in the biomedical and patient care markets. The book offers both a source of inspiration for new projects and a reliable source of information on how glycerol is replacing petrochemicals in many real world applications.
  • Emerging Nanotechnologies in Food Science

    • 1st Edition
    • Rosa Busquets
    • English
    Emerging Nanotechnologies in Food Science presents the current knowledge and latest developments in food nanotechnology, taking a multidisciplinary approach to provide a broad and comprehensive understanding of the field. Food nanotechnology is a newly emergent discipline that is fast-growing and evolving. The discipline continues to benefit from advances in materials and food sciences and has enormous scientific and economic potential. The book presents nano-ingredients and engineered nanoparticles developed to produce technologically improved food from both food science and engineering perspectives. In addition, subsequent chapters offer a review of recent outstanding inventions in food nanotechnology and legal considerations for the protection of intellectual property in this area. With its multidisciplinary team of contributors, this book serves as a reference book for the ever-growing food nanotechnology science.
  • Music, Passion, and Cognitive Function

    • 1st Edition
    • Leonid Perlovsky
    • English
    Music, Passion, and Cognitive Function examines contemporary cognitive theories of music, why they cannot explain music’s power over us, and the origin and evolution of music. The book presents experimental confirmations of the theory in psychological and neuroimaging research, discussing the parallel evolution of consciousness, musical styles, and cultures since Homer and King David. In addition, it explains that 'in much wisdom is much grief' due to cognitive dissonances created by language that splits the inner world. Music enables us to survive in this sea of grief, overcomes discomforts and stresses of acquiring new knowledge, and unifies the soul, hence the power of music.
  • Neural Data Science

    A Primer with MATLAB® and Python™
    • 1st Edition
    • Erik Lee Nylen + 1 more
    • English
    A Primer with MATLAB® and Python™ present important information on the emergence of the use of Python, a more general purpose option to MATLAB, the preferred computation language for scientific computing and analysis in neuroscience. This book addresses the snake in the room by providing a beginner’s introduction to the principles of computation and data analysis in neuroscience, using both Python and MATLAB, giving readers the ability to transcend platform tribalism and enable coding versatility.
  • Schering Symposium on Intrinsic and Extrinsic Factors in Early Mammalian Development, Venice, April 20 to 23, 1970

    Advances in the Biosciences
    • 1st Edition
    • Gerhard Raspé
    • English
    Advances in the Biosciences 6: Schering Symposium on Intrinsic and Extrinsic Factors in Early Mammalian Development, Venice, April 20 to 23, 1970 is a collection of papers presented at the Schering Symposium on Intrinsic and Extrinsic Factors in Early Mammalian Development, held in Venice, Italy, on April 20-23, 1970. Contributors explore intrinsic and extrinsic mechanisms underlying early development in mammals and cover topics ranging from transmission of maternal proteins into oocytes to normal and abnormal fertilization in mammals; experimental early parthenogenesis in mammals; and nutrient requirements for the culture of preimplantation embryos in vitro. This book is comprised of 33 chapters and begins with an overview of the oocyte and the egg, touching on subjects such as electron microscopy of the primary and secondary oocyte; experimental early parthenogenesis in mammals; and laparoscopic recovery of pre-ovulatory human oocytes after priming of the ovaries with gonadotrophins. The next section is devoted to intrinsic and extrinsic influence on the metabolism of preimplantation embryos and includes chapters dealing with the composition of oviductal and uterine fluids; the role of uterine proteins in embryonic development; sex chromosome markers as indicators in embryonic development; and manipulations of the blastocyst. The remaining chapters examine placental and fetal physiology, immunology and teratology, and differentiation of tissues. This monograph will be of interest to biologists and physiologists.
  • Molecular Characterization of Autophagic Responses Part B

    • 1st Edition
    • Volume 588
    • English
    Molecular Characterization of Autophagic Responses, Part B presents a collection of methods for the qualitative and quantitative evaluation of virtually all the morphological, biochemical, and functional manifestations of autophagy, in vitro, ex vivo and in vivo, in organisms as distant as yeast and man. Autophagy is an evolutionarily conserved mechanism for the lysosomal degradation of superfluous or dangerous cytoplasmic entities, and plays a critical role in the preservation of cellular and organismal homeostasis. Monitoring the biochemical processes that accompany autophagy is fundamental for understanding whether autophagic responses are efficient or dysfunctional.
  • Hearing Loss

    Causes, Prevention, and Treatment
    • 1st Edition
    • Jos J. Eggermont
    • English
    Hearing Loss: Causes, Prevention, and Treatment covers hearing loss, causes and prevention, treatments, and future directions in the field, also looking at the cognitive problems that can develop. To avoid the “silent epidemic” of hearing loss, it is necessary to promote early screening, use hearing protection, and change public attitudes toward noise. Successful treatments of hearing loss deal with restoring hearing sensitivity via hearing aids, including cochlear, brainstem, or midbrain implants. Both the technical aspects and effects on the quality of life of these devices are discussed. The integration of all aspects of hearing, hearing loss, prevention, and treatment make this a perfect one-volume course in audiology at the graduate student level. However, it is also a great reference for established audiologists, ear surgeons, neurologists, and pediatric and geriatric professionals.