Advances in Virus Research

1st Edition, Volume 97 - January 2, 2017
Editors: Margaret Kielian, Thomas Mettenleiter, Marilyn J. Roossinck
Language: English
Hardback ISBN:
9 7 8 - 0 - 1 2 - 8 1 1 8 0 1 - 6
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 1 1 8 0 2 - 3

Advances in Virus Research volume 97, the latest in the series first published in 1953, covers a diverse range of in-depth reviews, providing a valuable overview of the current f… Read more

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Advances in Virus Research volume 97, the latest in the series first published in 1953, covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology.

Chapter One: Biomedical and Catalytic Opportunities of Virus-Like Particles in Nanotechnology
- Abstract
- 1 What Is a Virus-Like Particle?
- 2 The Essentials of Protein VLP Structure
- 3 VLPs as Materials
- 4 VLPs as Templates for Constrained Material Synthesis
- 5 VLPs for Biomedical Delivery and Imaging
- 6 VLPs as Metabolic Compartments
- 7 VLPs as Stimulants of Immunity
- 8 Outlook
- Acknowledgments
Chapter Two: A Renaissance in Nepovirus Research Provides New Insights Into Their Molecular Interface With Hosts and Vectors
- Abstract
- 1 Introduction
- 2 Taxonomy and Genome Structure
- 3 Population Structure, Genetic Diversity, and Evolution
- 4 Genome Expression by Cap-Independent Translation and Polyprotein Processing
- 5 Replication Proteins and Assembly of Replication Complexes
- 6 Virion Structure and Encapsidation
- 7 Viral and Plant Factors Implicated in Cell-to-Cell Movement
- 8 Host Defense and Virus Counter-Defense Responses
- 9 Viral Symptom Determinants
- 10 Transmission
- 11 Disease Management
- 12 Conclusions and Future Prospects
- Acknowledgments
Chapter Three: Have NEC Coat, Will Travel: Structural Basis of Membrane Budding During Nuclear Egress in Herpesviruses
- Abstract
- 1 Introduction
- 2 The Role of NEC in Membrane Budding
- 3 NEC Structures
- 4 The Hexagonal Lattice of the NEC: Structure and Function
- 5 NEC Lattice Curvature
- 6 Regulation of NEC Lattice Assembly
- 7 NEC and Capsid Deenvelopment at the ONM
- 8 Summary
- Acknowledgments
Chapter Four: Nonsegmented Negative-Sense RNA Viruses—Structural Data Bring New Insights Into Nucleocapsid Assembly
- Abstract
- 1 The Nonsegmented Negative-Sense RNA Viruses
- 2 The RNA Replication Complex
- 3 The N⁰–P Complex
- 4 A Proposed Scenario for NC Handling and Assembly by the RNA Polymerase Complex
- 5 Conclusions and Future Directions
- Acknowledgments
Chapter Five: Modified Vaccinia Virus Ankara: History, Value in Basic Research, and Current Perspectives for Vaccine Development
- Abstract
- 1 Introduction
- 2 History and Development of MVA
- 3 MVA as Tool for Research in Poxvirus Biology
- 4 Recombinant MVA Vaccines Against Infectious Diseases
- 5 MVA as Third-Generation Vaccine Against Smallpox
- 6 Conclusions
Index

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Advances in Virus Research

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Margaret Kielian

Thomas Mettenleiter

Marilyn J. Roossinck