Skip to main content
Elsevier

Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 37
    • Annette M. Doherty
    • English
    Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.

  • Macrolide Antibiotics

    Chemistry, Biology, and Practice
    • 2nd Edition
    • Satoshi Omura
    • English
    Macrolide Antibiotics: Chemistry, Biochemistry, and Practice, Second Edition explores the discovery of new macrolide antibiotics, their function, and their clinical use in diseases such as cancer, AIDS, cystic fibrosis and pneumonia. This book discusses the creation of synthetic macrolides and the mechanisms of antibiotic activity. The uses for antimicrobial macrolides in clinical practice are also covered. This book is designed to appeal to both the basic and applied research communities interested in microbiology, bacteriology, and antibiotic/antifunga... research and treament.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 82
    • Alan R. Katritzky
    • English
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area-one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

  • Signal Transduction

    • 1st Edition
    • Bastien D. Gomperts + 2 more
    • English
    Signal Transduction is a well-illustrated, coherent look at cellular signaling processes. Beginning with the basics, it explains how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and then shows how these inputs are integrated and coordinated. The extensive color artwork provides the reader with a clearer comprehension of key topics, and margin notes are incorporated to highlight milestones in the evolution of signal transduction. This book serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields.

  • Vitamins and Hormones

    • 1st Edition
    • Volume 64
    • English
    First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

  • Trends in Drug Research III

    • 1st Edition
    • Volume 32
    • H. van der Goot
    • English
    The tradition of setting new trends in medicinal chemistry continued at the 13th Symposium where topics included chemical and biological diversity, new paradigms in drug action, and new insights in receptor mechanisms. Other topics of great interest discussed, and included in these proceedings, are the discoveries in green chemistry, the interface between organic synthesis and biosynthesis, the growing problem of resistant micro-organisms and the possibilities to identify new, and better, antibiotics. And finally, in recent developments, the discovery of small molecules with insulin sensitizing properties.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 40
    • English
    This volume features accounts of the biological rationale, design and clinical potential of drug molecules; summaries of structure-activity relationships in topical areas of medicinal chemistry and extensive references to the biology, medicinal chemistry and clinical aspects of each topic.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 39
    • English
    This volume covers contemporary advances in five important areas of pharmacology and medicinal chemistry including: a comprehensive account of inhibitors of the caspase family of proteolytic enzymes that represent a new class of anti-inflammatory and antiapoptotic agents of potential value in rheumatoid arthritis, and other peripheral and central indications; adoc umented survey of semi-synthetic and totally synthetic antibiotics and anti HIV agents and their sites of interaction; inhibitors of the intracellular enzyme acyl-CoA: cholesterol O-acyltransferase (ACAT) developed for the treatment of hypercholesterolemia... and recent progress in growth hormone secretagogues, with the focus on strategies to improve oral bioavailability and duration of action. Inhibition of the proteolytic enzyme, hepatitis C protease N-3(NS3), required for viral replication, is one of the most attractive targets for HCV infections. Progress and prospects in the design of peptide and non-peptide inhibitors are described here. design and clinical potential of new drug molecules; valuable summaries of structure-activity relationships in topical areas of medicinal chemistry; and extensive references to the biology, medicinal chemistry and clinical aspects of each topic.

  • Handbook of Pesticide Toxicology

    Principles and Agents
    • 2nd Edition
    • Robert Krieger
    • English
    This revision of the highly acclaimed Hayes' Handbook of Pesticide Toxicology is an in-depth, scientific sourcebook concerning use, properties, effects, and regulation of pesticides. This edition is a comprehensive examination by international experts from academia, government research, and the private sector of critical issues related to the need, use, and nature of chemicals used in modern pest management. This two-volume set contains up-to-date information on a broad range of topics which establishes context of pesticide use and outlines how they are scientifically evaluated. Experts from a variety of disciplines contribute to this work. Some provide a fresh look at existing information, and others look ahead at issues that are central to understanding pesticide use and toxicology in modern integrated pest management.

  • Principles of Clinical Pharmacology

    • 1st Edition
    • Arthur J. Atkinson Jr. + 4 more
    • English
    The rate of introduction of new pharmaceutical products has increased rapidly over the past decade, and details learned about a particular drug become obsolete as it is replaced by newer agents. Principles of Clinical Pharmacology focuses on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. The coverage of these principles in this book will be of particular benefit to individuals engaged either in the teaching or study of sound therapeutic technique or in the investigation of pharmacological agents.

  • Side Effects of Drugs Annual

    • 1st Edition
    • Volume 24
    • English
    The Side Effects of Drugs Annual is designed to provide a critical and up-to-date account of new information related to adverse drug reactions and interactions from the clinician's point of view. Under the supervision of the series editors, an international team of expert authors have gathered together the latest information on adverse drug effects from the international literature. In addition to describing new reports of adverse drug effects, the authors have subjected those reports to critical analysis, setting them into context in terms of clinical relevance and importance, and cross-referring to previous reports where necessary. New adverse effects are reported and evaluated and previously reported adverse effects are re-evaluated in the light of the most recent information. A special feature is the reviews, in which selected adverse effects are discussed in depth. The use of the book is enhanced by two separate indexes, allowing the reader to enter the text by drug name, adverse effect name, or drug interaction. The current Annual is the first update of the standard encyclopaedic work in this field, http://www.elsevier.... Side Effects of Drugs, Fourteenth Edition, which was published in December 2000.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 38
    • English

  • Histopathology of Preclinical Toxicity Studies

    Interpretation and Relevance in Drug Safety Evaluation
    • 2nd Edition
    • Peter Greaves
    • P. Greaves
    • English
    This book describes histopathological assessment of preclinical toxicology studies that are conducted to assess the safety of novel drugs. It discusses the implications of drug-induced changes that may be relevant to the critical early stages of the development of new therapeutic agents, notably prior to their first administration to humans and during early clinical trials. Covering virtually all aspects of drug-induced pathology in preclinical toxicity studies, the book is termed the 'gold standard' in the illustration of histopathology. This second revised edition continues to fill the gap for pathology literature relating to the development of new medicines and assessment of their safety based on preclinical studies. In addition to the updated references this edition contains many older references, some out of reach of modern computer based search tools.

  • Side Effects of Drugs Annual

    • 1st Edition
    • Volume 23
    • English
    The http://www.elsevier.... Effects of Drugs Annual offers clinicians in areas as widespread as dermatology, neuroscience, endocrinology and many other medical disciplines a reliable and critical overview of all that is known in the area of Adverse Drugs Reactions.An international team of specialists in the various areas have contributed to the current Annual. Particular attention is devoted to those publications providing essentially new information or throwing new light on problems already recognized. All that is truly new and informative (or points to what is misleading) is critically selected from the year's writing. Every four years the previous set of four Annuals is summarised and evaluated, leading to the publication of the update of the major reference work, http://www.elsevier.... Side Effects of Drugs. The /locate/isbn/0444500... updated Edition of Meyler's, published in December 2000, provides the reader with a summary of Side Effects of Drugs Annuals 20 - 23.

  • Vitamins and Hormones

    • 1st Edition
    • Volume 60
    • Gerald Litwack + 1 more
    • English
    Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. Now, new discoveries have proved that several of the vitamins function as hormones and many of the substances inferred by the title of the serial function in signal transduction processes. Accordingly, the Editor-in-Chief has expanded the scope of the serial to reflect this newer understanding of function-structure relationships in cellular communication. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms.This volume comprises three groups of contributors. The first three papers deal with receptors and their actions. The second group of three papers are on diabetes and specific hormones. The last three papers are presentations on various aspects of vitamins and growth factors.

  • Heart Physiology and Pathophysiology

    • 4th Edition
    • Nicholas Sperelakis + 3 more
    • English
    Heart Physiology and Pathophysiology, 4E, provides the foundation for the scientific understanding of heart function and dysfunction, and bridges the gap between basic cardiovascular science and clinical cardiology. This comprehensive text covers all the important aspects of the heart and vascular system. The most important and relevant disorders are presented, with emphasis on the mechanisms involved. The first three editions of this book developed a reputation as the leading reference in cardiovascular science for researchers and academic cardiologists. This recent edition has been updated, expanded, and includes a number of new contributors. It has also been remodeled to expand its usage as a text reference for cardiology residents, practicing cardiologists, and graduate students.

  • The Quinolones

    • 3rd Edition
    • Vincent T. Andriole
    • English
    Quinolones constitute a large class of synthetic antimicrobial agents that are highly effective in the treatment of many types of infectious diseases, particularly those caused by bacteria. New quinolones are continually being developed as bacterial species develop resistance to existing quinolones. This book presents the most current information available in our continual struggle to conquer disease. Over time, bacteria become resistant to medicines that are used to combat them. Because of this, the medical world is always in search of new and improved ways to battle these disease-causing bacteria. Quinolones are at the forefront of this research. Edited by one of the world's foremost authorities on the subject, the third edition of this highly successful title will serve as a valuable tool for primary care physicians and researchers interested in a comprehensive, up-to-date reference on the chemistry, mechanisms of action, development of resistance, and clinical efficacy of both currently available and newer quinolone compounds under investigation. This is the eagerly anticipated fully revised edition of the standard reference in the field.

  • HIV: Molecular Biology and Pathogenesis: Viral Mechanisms

    • 1st Edition
    • Volume 48
    • English
    The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, and describe ongoing progress in developing animal models and prophylactic vaccines.The two volumes, covering viral mechanisms and clinical applications, respectively, are written by an international collection of AIDS expers from North America, Europe, Australia, and Asia.

  • Encyclopedia of Separation Science

    • 1st Edition
    • Ian D. Wilson + 2 more
    • English
    The Encyclopedia of Separation Science is the most comprehensive resource available on the theory, techniques, and applications of separation science. The work presents information on three levels. The first volume contains Level 1, which provides a broad overview of the theory of the 12 main categories of separation techniques. Volumes 2-4 (Level 2) expand coverage with detailed theoretical and technical descriptions of particular techniques. The remaining Volumes 5-9 (Level 3) cover applications of these techniques from the micro to the macro, and also from the analytical laboratory bench to large-scale industrial processes. Volume 10 consists mainly of the index. Initial access to the online version offering extensive hypertext linking and advanced search tools is available with purchase. Ongoing access is maintained for a minimum annual fee. The Encyclopedia of Separation Science is the first truly comprehensive work covering the whole of separation theory, methods, and techniques. This encyclopedia will be invaluable to researchers and professionals across a wide range of areas in academia and industry. Enclyclopedia of Separation Science is available online via ScienceDirect offering enhanced features such as extensive cross-referencing and dynamic linking. For more information please (http://www.info.sci... click here.)

  • Chemistry and Biology

    • 1st Edition
    • Volume 54
    • English
    Alkaloids are a major group of natural products derived from a wide variety of organisms, which are widely used as medicinal and biological agents. This series is world-renowned as the leading compilation of current reviews of this vast field.Internationall... acclaimed for more than forty years, The Alkaloids , founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structure elucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, or various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Over the years, this series has become the standard in natural product chemistry to which all other book series aspire. The Alkaloids: Chemistry and Biology endures as an essential reference for all natural product chemists and biologists who have an interest in alkaloids, their diversity, and their unique biological profile.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 37
    • English
    This volume reviews recent advances in five important areas of medicinal chemistry which will be of interest both to chemists and to scientists of other disciplines engaged in medicines research and development. Included are accounts of successful drug discovery programmes, disease targets of unmet medical need, and recent progress in new technologies which are considered by many to hold the key to future developments in medicinal chemistry.The style and organisation of chapters follow a similar pattern to previous volumes but references, where appropriate, now include website addresses of the World Wide Web.

  • Side Effects of Drugs Annual

    • 1st Edition
    • Volume 22
    • English
    Based on the results of an extensive literature search, an international team of authors have collected the latest information on adverse drug effects from the world literature. New adverse effects are reported and evaluated and previously reported adverse effects are re-evaluated in the light of the most recent information. The book provides the reader with a critical and up-to-date overview of the most recent developments in the field. Selected adverse effects are discussed in the special reviews. Two separate indexes enhance the book and allow the author to enter the text by drug name or by adverse effect. The Annual can be used independently or as a supplement to the standard Encyclopedic work in this field, Meyler's Side effects of Drugs, of which, thehttp://www.elsevi... Fourteenth Edition was published in December 2000.

  • Adenosine Receptors and Parkinson's Disease

    • 1st Edition
    • Hiroshi Kase + 2 more
    • English
    This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. This book covers how the Parkinson's disease antagonist drug, A2A, has been researched, developed, and tested. It is an essential book for researchers interested in the basal ganglia, purine biology, and Parkinson's Disease.

  • Encyclopedia of Violence, Peace, and Conflict

    • 1st Edition
    • Lester R. Kurtz
    • English
    The Encyclopedia of Violence, Peace, and Conflict, a three-volume set written by more than 200 eminent contributors from around the world, takes advantage of increasing, worldwide awareness in the public, private, commercial, and academic sectors about manifestations of violence in all segments of society. While the contributors do not use these volumes to make specific arguments, they do describe and clarify the developments in thought that have led to current theories about and positions on violence and peace. Our reviewers consistently note that while many in-depth studies of war, peace, and aggression exist, the attendant specialization keeps scholars from learning about related fields. No publication competing with the Encyclopedia of Violence, Peace, and Conflict can satisfy their need for a vast introductory work to such a diverse and socially-important field. This major work includes more than 190 multidisciplinary articles with over 1,000 cross-references and more than 2,000 bibliography entries for further reading which are arranged alphabetically for easy access.

  • Membrane Permeability: 100 Years Since Ernest Overton

    • 1st Edition
    • Volume 48
    • English
    Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs. Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid membrane structure. His most quoted paper on the osmotic properties of cells laid the foundation for the modern concepts of membrane function, most notably important in anesthesia. This book is designed to celebrate the centennial anniversary (in the first chapter) of Overton's work. Subsequent chapters present readers with up-to-date concepts of membrane structure and function and the challenge they pose for new explorations.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 36
    • English

  • Advances in Pharmacology

    • 1st Edition
    • Volume 46
    • English
    Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.

  • Side Effects of Drugs Annual

    • 1st Edition
    • Volume 21
    • English
    The Side Effects of Drugs Annual has been published each year since 1977. It is designed to provide a critical and up-to date account of new information relating to adverse drug reactions and interactions from the clinician's point of view. The Annual can be used independently or as a supplement to the standard encyclopedic work in this field, Meyler's Side Effects of Drugs, of which, the http://www.elsevier.... Edition was published in December 2000.The present Annual reviews all reports presenting significant new information on adverse reactions to drugs from July 1996 to June 1997. During the production of this Annual, more recent papers have been included. The use of the book is enhanced by two separate indexes, allowing the reader to enter the text by drug name, adverse effect name, or drug interaction.

  • Oxidants and Antioxidants, Part B

    • 1st Edition
    • Volume 300
    • John N. Abelson + 1 more
    • English
    General Description of the Series:The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

  • A Dictionary of Pharmacology and Allied Topics

    • 2nd Edition
    • D.R. Laurence + 1 more
    • English
    This dictionary spans the practice of pharmacology, and of allied sciences insofar as they are related to it, with particular emphasis on the development, regulation and use of human medicine. It is offered to students as well as to professionals in pharmacology and allied sciences for reference and for browsing, and as a bedside book and travelling companion. Its size (approximately 2000 entries) is appropriate for these uses.Features of this dictionary:• Provides definitions of terms in pharmacology, both basic and clinical• Gives information on new medicine development and official regulations• Covers allied topics, including statistics, ethics, scientific miscounduct, authorship, publication and law.

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 33
    • David Robertson + 5 more
    • English
    Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expectedto provide the basis for entirely new future therapies.

  • Asthma

    Basic Mechanisms and Clinical Management
    • 3rd Edition
    • Peter J. Barnes + 2 more
    • English
    Now available in its Third Edition, Asthma: Basic Mechanisms and Clinical Management has become the reference text in asthma. This highly successful text sheds new light on the basic physiological and molecular mechanisms of asthma, how current treatments work, and how best to apply the latest knowledge to control this important disease. The Third Edition has undergone radical revision and includes several new chapters. It retains the virtues of the previous volumes by bringing together all of the recent research findings by internationally recognized experts on the causative mechanisms of asthma, including in-depth clinical aspects and therapy. The book presents an integrated approach toward the treatment of this disease with new concepts, changes in asthma management, and the development of new therapeutic agents. Asthma provides extensive references for researchers and clinicians who need to keep abreast of recent developments in this rapidly expanding field.

  • Cytokines

    • 1st Edition
    • Anthony R. Mire-Sluis + 1 more
    • English
    This book provides comprehensive coverage of the cytokines from a pharmacological approach. The chapters are presented in a consistent format allowing easy cross-reference, with sample diagrams and a summary table of essential facts for each chapter at the end of the book.Cytokines is unique in stressing cytokine biology and the application of research data to provide disease therapy. With 33 detailed and up-to-date chapters about individual cytokines, this comprehensive reference will provide both clinicians and researchers in immunology and pharmacology with invaluable information.

  • Advances in Pharmacology

    • 1st Edition
    • Volume 44
    • English
    Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.

  • Encyclopedia of Mental Health, Volume 1

    • 1st Edition
    • Bozzano G Luisa
    • English
    This encyclopedia presents a comprehensive overview of the many genetic, neurological, psychological and social factors that affect mental health. It also describes the impact of mental health on the individual and society.

  • Encyclopedia of Mental Health, Three-Volume Set

    • 1st Edition
    • Howard S. Friedman + 8 more
    • English
    Mental health is arguably one of the biggest issues facing modern society. The Encyclopedia of Mental Health presents a comprehensive overview of the many genetic, neurological, social, and psychological factors that affect mental health. It describes the impact of mental health on the individual and society, and illustrates the factors that aid positive mental health. 196 peer-reviewed articles written by more than 250 expert authors include essential material on assessment, theories of personality, specific disorders, therapies, forensic issues, ethics, cross-cultural and sociological aspects. Professionals and libraries find this timely work indispensable.

  • Encyclopedia of Mental Health, Volume 2

    • 1st Edition
    • Bozzano G Luisa
    • English

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 35
    • English
    Eminent scientists at the cutting edge of pharmacology and medicinal chemistry research provide us with yet another excellent addition to this famous series. The focus on bacterial resistance mechanisms serves to highlight an important area of unmet medical need requiring the attention of medicinal chemists. Five topical subjects are reviewed: the biosynthesis, metabolism and function of Vitamin D3 and the potential application of its analogues in bone disorders and immune-related diseases; the therapeutic potential of neurokinin antagonists; opioid receptor antagonists; the mechanisms of bacterial resistance; and a survey of recent advances in cannabinoid research. This volume will deservedly take its place in clinical and industrial pharmaceutical libraries, and will prove invaluable to medicinal chemists.

  • Side Effects of Drugs Annual

    • 1st Edition
    • Volume 20
    • English
    The Side Effects of Drugs Annual has been published each year since 1977. It is designed to provide a critical and up-to-date account of new information related to adverse drug reactions and interactions from the clinician's point of view.Under the supervision of the series editors, an international team of expert authors have gathered together the latest information on adverse drug effects from the international literature. In addition to describing new reports of adverse drug effects, the authors have subjected those reports to critical analysis, setting them into context in terms of clinical relevance and importance, and cross-referring to previous reports where necessary. New adverse effects are reported and evaluated and previously reported adverse effects are re-evaluated in the light of the most recent information. A special feature is the reviews, in which selected adverse effects are discussed in depth. The use of the book is enhanced by two separate indexes, allowing the reader to enter the text by drug name, adverse effect name, or drug interaction.The Annual can be used independently or as a supplement to the standard encyclopaedic work in this field, Meyler's Side Effects of Drugs, of which, the http://www.elsevier.... Edition was published in December 2000.

  • Stable Isotopes in Pharmaceutical Research

    • 1st Edition
    • Volume 26
    • T.R. Browne
    • English
    Stable isotope techniques offer advantages in safety, sensitivity, specificity, and economy for many types of pharmaceutical investigations when compared to conventional techniques. Nevertheless, pharmaceutical researchers are slow to embrace stable isotope techniques.This book assembles in one place comprehensive reviews of the many applications of stable isotopes and the background material necessary to understand the application. This approach is a deliberate attempt to encourage the usage of stable isotopes in pharmaceutical research. A bonus to the reader is the high standard of contributions from a very talented and diverse group of investigators.

  • A Manual of Adverse Drug Interactions

    • 5th Edition
    • J.P. Griffin + 1 more
    • English
    For twenty years this book, now in its 5th edition, has provided information on adverse drug interactions that is unrivalled in coverage and scholarship.Adverse drug reactions, many of them ascribable to interactions with other drugs or with chemical substances in food or the environment, are thought to cause or complicate one in twenty of hospital admissions.The book is conveniently divided into two parts: Part 1 comments on drug interactions and their mechanisms, on a pharmacokinetic and pharmacodynamic level, while Part 2 consists of drug interaction tables, divided and subdivided into categories of disorders, and the drugs used in the treatment of these disorders.If safety in drugs is to improve, education of prescribers is vitally important. This book, with its up-to-date and coordinated approach, serves that purpose well. The real threat, as the authors remind us, is the ignorance of practitioners, not the drug itself. The volume is therefore an essential addition to the shelves of those responsible for the prescription of drugs, in order to prevent a potential backlash when used in combination with other drugs or chemical substances.

  • Fundamentals of Toxicologic Pathology

    • 1st Edition
    • Colin G. Rousseaux + 1 more
    • English
    Fundamentals of Toxicologic Pathology focuses on providing basic information integrated from both toxicology and pathology dealing with the mechanisms of toxic injury and morphologic expression of that injury at the subcellular, cellular, and tissue levels. This text is an enhanced and edited version of the Handbook of Toxicologic Pathology, creating a more concise and affordable text ideal for graduate students of toxicologic pathology and scientists working in academia or industry.

  • Catecholamines: Bridging Basic Science with Clinical Medicine

    • 1st Edition
    • Volume 42
    • English
    This volume in Advances in Pharmacology focuses on all aspects of catecholamine research, from very basic to medical. It is broad based and covers many areas within physiology and medicine.

  • Advances in Cancer Research

    Cumulative Subject Index
    • 1st Edition
    • Volume 73
    • English
    Academic Press proudly presents this Cumulative Subject Index covering Volumes 50-72 of Advances in Cancer Research. In one comprehensive source, the interested reader can find references to specific articles on topics such as breast cancer, prostate cancer, Kaposi's sarcoma, Burkitt's lymphoma, leukemias, oncogenes, transcription factors, tumor genetics, p53, T-cell receptors, and drug resistance. This cumulative index will serve not only as a complete overview of the major topics published in Advances in Cancer Research, but also as an indicator of the progress made in cancer research over the last ten years.

  • Heparin-Binding Proteins

    • 1st Edition
    • H. Edward Conrad
    • English
    This book describes the complex structures of heparins and heparan sulfates (heparinoids) and how they are generated by their biosynthetic pathways. The book also details the methodologies for studying these structures and their cellular metabolism. Heparin-Binding Proteins introduces the general nature of interactions between heparinoids and proteins, and presents the role for these structures in their interactions with the proteins of the hemostatic mechanisms, fibroblasts growth factors, superoxide dismutase, and lipoproteins.

  • Drug-Drug Interactions: Scientific and Regulatory Perspectives

    • 1st Edition
    • Volume 43
    • English
    Drug–Drug Interactions is a comprehensive review of the scientific and regulatory perspectives of drug–drug interactions from the point-of-view of academia, industry, and government regulatory agencies. This book is intended for professionals in the pharmaceutical industry, health care, and governmental regulatory agencies. Topics of interest include the mechanistic understanding of drug–drug interactions, the prediction of drug–drug interaction potential of new drugs, and the avoidance of clinically significant drug–drug interaction in patients.

  • Hormones and Signaling

    • 1st Edition
    • Volume 1
    • Bert W. O'Malley + 6 more
    • English
    Hormones and Signaling focuses on the mechanism of gene regulation at the cellular level. It also covers the way hormones act to modulate gene regulation and animal development.

  • Lipases, Part A: Biotechnology

    • 1st Edition
    • Volume 284
    • John N. Abelson + 1 more
    • English
    The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 270 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences.

  • Diuretic Agents

    Clinical Physiology and Pharmacology
    • 1st Edition
    • Donald W. Seldin + 1 more
    • English
    The only comprehensive work to cover all aspects of diuretic agents, the book discusses the pharmacology and toxicology of diuretic agents as well as the physiological effects. Experts in the field present the principles and experimental approaches for the study of interactions between pharmacologic compounds in relation to specific target organs. Diuretic Agents contains information on the mechanisms of action and application of diuretics, and details FDA regulations and pharmaceutical industry guidelines.

  • XIVth International Symposium on Medicinal Chemistry

    • 1st Edition
    • Volume 28
    • F. Awouters
    • English
    Vaso-occlusive disorders including unstable angina, myocardial infarction, transient ischemic attacks, stroke and peripheral artery disease remain the major sources of morbidity and mortality in western civilization. Platelet activation and resulting platelet aggregation play a major role in the pathogenesis of these thromboembolic diseases. Recognition of the contribution of platelets to the pathophysiology of cardiovascular disease has provided impetus for the continued search for new antiplatelet agents. Hence, over the past two decades many strategies have been evaluated in the search for efficacious mechanisms to reduce platelet function. The medical need for more efficacious antithrombotic drugs and the growing understanding of the role of platelets in vascular injury have catalyzed the extensive evaluation of novel approaches to control platelet function. Along these lines, the volume therefore provides an in-depth assessment of ongoing clinical trials, new and clinically established agents, and other developments in this rapidly developing field.

Related subjects