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Elsevier

Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • Comprehensive Heterocyclic Chemistry III

    A Review of the Literature 1995-2007 1- 15
    • 1st Edition
    • Alan R. Katritzky + 3 more
    • English
    Comprehensive Heterocyclic Chemistry III (CHEC-III) is a new 15-volume reference work which provides the first point of entry to the literature for all scientists interested in heterocyclic ring systems. Since publishing in 1984, Comprehensive Heterocyclic Chemistry (CHEC) has become the standard work on the subject, indispensable to all serious readers in the interdisciplinary areas where heterocycles are employed. CHEC-III builds on and complements the material in CHEC and CHEC-II and is designed to be used both alone and in conjunction with these two works. Written by leading scientists who have evaluated and summarized the most important data published over the last decade, Comprehensive Heterocyclic Chemistry III will be an invaluable addition to the reference library of those working with heterocyclic ring systems.

  • State Estimation in Chemometrics

    The Kalman Filter and Beyond
    • 1st Edition
    • Pierre C. Thijssen
    • English
    This unique text blends together state estimation and chemometrics for the application of advanced data-processing techniques. It further applies system theory in order to develop a modular framework to be implemented on computer for the development of simple intelligent analyzers. Short reviews on the history of state estimation and chemometrics are given, together with examples of the applications described, including classical estimation, state estimation, non-linear estimation, the multi-component, calibration and titration systems and the Kalman filter. The contents are very systematic and build the ideas up logically to appeal to specialist post-graduates working in this area, together with professionals in other areas of chemistry and engineering.

  • The Smallest Biomolecules: Diatomics and their Interactions with Heme Proteins

    • 1st Edition
    • Abhik Ghosh
    • English
    This is not a book on NO biology, nor about hemoglobin, nor about heme-based sensors per se. Of course, it covers all these topics and more, but above all, it aims at providing a truly multidisciplinary perspective of heme-diatomic interactions. The overarching goal is to build bridges among disciplines, to bring about a meeting of minds. The contributors to this book hail from diverse university departments and disciplines – chemistry, biochemistry, molecular biology, microbiology, zoology, physics, medicine and surgery, bringing with them very different views of heme-diatomic interactions. The hope is that the juxtaposition of this diversity will lead to increased exchanges of ideas, approaches, and techniques across traditional disciplinary boundaries. The authors represent a veritable Who’s Who of heme protein research and include John Olson, Tom Spiro, Walter Zumft, F. Ann Walker, Teizo Kitagawa, W. Robert Scheidt, Pat Farmer, Marie-Alda Gilles-Gonzalez, and many other equally distinguished scientists.

  • Strategies and Tactics in Organic Synthesis

    • 1st Edition
    • Volume 7
    • Michael Harmata
    • English
    A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic. Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project. In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world.

  • Advances in Quantum Chemistry

    Current Trends in Atomic Physics
    • 1st Edition
    • Volume 53
    • Sten Salomonson + 1 more
    • English
    Advances in Quantum Chemistry presents surveys of current developments in this rapidly developing field that falls between the historically established areas of mathematics, physics, chemistry, and biology. With invited reviews written by leading international researchers, each presenting new results, it provides a single vehicle for following progress in this interdisciplinary area.

  • Medical Applications of Mass Spectrometry

    • 1st Edition
    • Karoly Vekey + 2 more
    • English
    Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine.The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 62
    • Graham A. Webb
    • English
    Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has grown to such importance as NMR spectroscopy. It is used in all branches of science when precise structural determination is required and when the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy.

  • Modeling of Chemical Reactions

    • 1st Edition
    • Volume 42
    • R.W. Carr
    • English
    Modeling of Chemical Reactions covers detailed chemical kinetics models for chemical reactions. Including a comprehensive treatment of pressure dependent reactions, which are frequently not incorporated into detailed chemical kinetic models, and the use of modern computational quantum chemistry, which has recently become an extraordinarily useful component of the reaction kinetics toolkit. It is intended both for those who need to model complex chemical reaction processes but have little background in the area, and those who are already have experience and would benefit from having a wide range of useful material gathered in one volume. The range of subject matter is wider than that found in many previous treatments of this subject. The technical level of the material is also quite wide, so that non-experts can gain a grasp of fundamentals, and experts also can find the book useful.

  • The Chemistry of Pincer Compounds

    • 1st Edition
    • David Morales-Morales + 1 more
    • English
    Pincer complexes are formed by the binding of a chemical structure to a metal atom with at least one carbon-metal bond. Usually the metal atom has three bonds to a chemical backbone, enclosing the atom like a pincer. The resulting structure protects the metal atom and gives it unique properties.The last decade has witnessed the continuous growth in the development of pincer complexes. These species have passed from being curiosity compounds to chemical chameleons able to perform a wide variety of applications. Their unique metal bound structures provide some of the most active catalysts yet known for organic transformations involving the activation of bonds. The Chemistry of Pincer Compounds details use of pincer compounds including homogeneous catalysis, enantioselective organic transformations, the activation of strong bonds, the biological importance of pincer compounds as potential therapeutic or pharmaceutical agents, dendrimeric and supported materials.

  • Electrochemistry in Light Water Reactors

    Reference Electrodes, Measurement, Corrosion and Tribocorrosion Issues
    • 1st Edition
    • Volume 49
    • R-W Bosch + 2 more
    • English
    There has long been a need for effective methods of measuring corrosion within light water nuclear reactors. This important volume discusses key issues surrounding the development of high temperature reference electrodes and other electrochemical techniques. The book is divided into three parts with part one reviewing the latest developments in the use of reference electrode technology in both pressurised water and boiling water reactors. Parts two and three cover different types of corrosion and tribocorrosion and ways they can be measured using such techniques as electrochemical impedance spectroscopy. Topics covered across the book include in-pile testing, modelling techniques and the tribocorrosion behaviour of stainless steel under reactor conditions.Electroch... in light water reactors is a valuable reference for all those concerned with corrosion problems in this key technology for the power industry.

  • Thermodynamics, Solubility and Environmental Issues

    • 1st Edition
    • Trevor Letcher
    • English
    Environmental problems are becoming an important aspect of our lives as industries grow apace with populations throughout the world. Thermodynamics, Solubility and Environmental Issues highlights some of the problems and shows how chemistry can help to reduce these them. The unifying theme is Solubility – the most basic and important of thermodynamic properties. This informative book looks at the importance and applications of solubility and thermodynamics, in understanding and in reducing chemical pollution in the environment. Written by experts in their respective fields and representing the latest findings in this very important and broad area. A collection of twenty-five chapters cover a wide range of topics including; mining, polymer manufacture and applications, radioactive wastes, industries in general, agro-chemicals, soil pollution and biology, together with the basic theory and recent developments in the modelling of environmental pollutants.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 45
    • F.D. King + 1 more
    • English
    The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process. What defines a ‘quality lead’, where these ‘quality leads’ come from and how one discovers them has been the subject of intense debate within the pharmaceutical industry, relies upon defining those properties that historically have led to successful drug discovery. This volume addresses these questions and specifically discusses diabetes, obesity and tuberculosis.

  • Handbook of Microdialysis

    Methods, Applications and Perspectives
    • 1st Edition
    • Volume 16
    • English
    Microdialysis is currently one of the most important in vivo sampling methods in physiology and pharmacology. It is used to determine the chemical components of the fluid in the extracellular space of tissues. The technique is now well established in neuroscience research and is used excessively in behavioral neuroscience to determine the concentrations and identities of molecules in brain tissues, and their change due to behavior, hormonal and transmitter changes in the nervous system. The book provides a detailed comprehensive overview of the technology and its applications, including application in pathology, drug development, and the application in the clinic. The authors are all well known researchers in Neuroscience and experts in the use of Microdialysis. Organized into two parts of seven sections, the Handbook of Microdialysis critically examines recent developments in the field through a variety of chapters written by an internationally acclaimed group of authors. It is the first comprehensive handbook covering the technology of Microdialysis and its applications in Neuroscience.

  • Tip Enhancement

    • 1st Edition
    • English
    This book discusses the recent advances in the area of near-field Raman scattering, mainly focusing on tip-enhanced and surface-enhanced Raman scattering. Some of the key features covered here are the optical structuring and manipulations, single molecule sensitivity, analysis of single-walled carbon nanotubes, and analytic applications in chemistry, biology and material sciences. This book also discusses the plasmonic materials for better enhancement, and optical antennas. Further, near-field microscopy based on second harmonic generation is also discussed. Chapters have been written by some of the leading scientists in this field, who present some of their recent work in this field.

  • The Encyclopedia of Mass Spectrometry

    Volume 6: Ionization Methods
    • 1st Edition
    • Michael L. Gross + 1 more
    • English
    Volume 6: Ionization Methods captures the story of molecular ionization and its phenomenal evolution that makes mass spectrometry the powerful method it is today. Chapters 1 and 2 cover fundamentals and various issues that are common to all ionization (e.g., accurate mass, isotope clusters, and derivatization). Chapters 3-9 acknowledge that some ionization methods are appropriate for gas-phase molecules and others for molecules that are in the solid or liquid states. Chapters 3-6 cover gas-phase molecules, dividing the subject into: (1) ionization of gas-phase molecules by particles (e.g., EI), (2) ionization by photons, (3) ionization by ion-molecule and molecule-molecule reactions (e.g., APCI and DART), and ionization in Strong electric fields (i.e., Electrohydrodynamic and Field Ionization/Desorptio... "Ionization in a Strong Electric Field" illustrates the transition to ionization of molecules in the solid or liquid states, covered in Chapters 7-9: (1) spray methods for ionization (e.g., electrospray), (2) desorption ionization by particle bombardment (e.g., FAB), and (3) desorption by photons (e.g., MALDI). Electrospray and MALDI also lead to applications in biophysical chemistry, the theme of Chapter 10. Chapter 11 reconsiders ionization from the view of choosing an ionization method. The range of subjects is from ionization of organic and biomolecules to the study of microorganisms.

  • The Langevin and Generalised Langevin Approach to the Dynamics of Atomic, Polymeric and Colloidal Systems

    • 1st Edition
    • Ian Snook
    • English
    The Langevin and Generalised Langevin Approach To The Dynamics Of Atomic, Polymeric And Colloidal Systems is concerned with the description of aspects of the theory and use of so-called random processes to describe the properties of atomic, polymeric and colloidal systems in terms of the dynamics of the particles in the system. It provides derivations of the basic equations, the development of numerical schemes to solve them on computers and gives illustrations of application to typical systems.Extensive appendices are given to enable the reader to carry out computations to illustrate many of the points made in the main body of the book.

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 41
    • English
    Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Sections I-IV are disease orientated and generally report on specific medicinal agents. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design. Section VII looks at Trends and Perspectives in the pharmaceuticals market.

  • The Electrochemistry and Characteristics of Embeddable Reference Electrodes for Concrete

    • 1st Edition
    • Volume 43
    • R Myrdal
    • English
    Using reference electrodes to monitor the electrochemical potential of steel reinforcement in concrete is a well established technique for assessing the severity of corrosion and for controlling cathodic protection systems. This report gives a state-of-the-art overview of the electrochemical and physical characteristics and performance of embeddable reference electrodes for concrete, and the method used for installing them.The report first reviews electrochemical potential and reference electrodes in general. It then assesses the different types of reference electrodes for concrete. Finally, it considers key issues such as location and quality control which need to be considered when installing reference electrodes in steel-reinforced concrete structures.

  • The Alkaloids

    Chemistry and Biology
    • 1st Edition
    • Volume 63
    • Geoffrey A. Cordell
    • English
    This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than forty years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids.

  • Coherent Synchronized Oxidation Reactions by Hydrogen Peroxide

    • 1st Edition
    • Tofik M. Nagiev
    • English
    Describes the relations between reactions in chemical and biochemical systems with special emphasis to high selective oxidation reactions by hydrogen peroxide.Outlines possible ways for the application of these reactions in an industrial scale.

  • Solution Chemistry

    Minerals and Reagents
    • 1st Edition
    • Volume 17
    • P. Somasundaran + 1 more
    • English
    Surfactants have been used for many industrial processes such as flotation, enhanced oil recovery, soil remediation and cleansing. Flotation technology itself has been used in industry since the end of the 19th century, and even today it is an important method for mineral processing and its application range is expanding to other areas. This technology has been used in the treatment of wastewater, industrial waste materials, separation and recycling of municipal waste, and some unit processes of chemical engineering. The efficiency of all these operations depends primarily on the interactions among surfactants, solids and media. In this book, the fundamentals of solution chemistry of mineral/surfactant systems are discussed, as well as the important calculations involved. The influence of relevant physico-chemical conditions are also presented in detail.

  • The Encyclopedia of Mass Spectrometry

    Volume 8: Hyphenated Methods
    • 1st Edition
    • English
    Volume 8: Hyphenated Methods Starting with gas chromatography–mass spectrometry (GC–MS) and continuing through GCxGC–MS, LC–MSn, and LC–NMR–MS, hyphenated methods have revolutionized chemical analysis. This volume covers that revolution in two parts. The first (Chapters 1–4) describes principles, instrumentation, and technology, and the second (Chapters 5–10) organizes major application areas in GC–MS and LC–MS. After a general introduction (Chapter 1), attention is paid to principles and instrumentation of GC–MS (Chapter 2) and LC–MS (Chapter 3). Other hyphenated methods, including online combinations of capillary electromigration methods and supercritical fluid chromatography with mass spectrometry, are in Chapter 4. Applications are then covered in the remaining chapters. The application-oriented chapters are focused on the role of mainly LC–MS in the pharmaceutical field (Chapter 5) and biochemical and biotechnological applications (Chapter 10), and the application of both GC–MS and LC–MS in relation to environmental analysis (Chapter 6), food safety and food analysis (Chapter 7), characterization of natural products (Chapter 8), and clinical, toxicological, and forensic analysis (Chapter 9).

  • Interface Science in Drinking Water Treatment

    Theory and Applications
    • 1st Edition
    • Volume 10
    • Gayle Newcombe + 1 more
    • English
    It is difficult to imagine anything more important to the human population than safe drinking water. Lack of clean drinking water is still the major cause of illness and death in young children in developing countries. In more fortunate communities, where water treatment is practiced, the primary aim of water authorities is to provide water that is free from pathogens and toxins. Most countries now have water quality regulations, or guidelines, which are driving water authorities to produce purer water, with the minimum of contamination from natural or man-made origin. At the same time, consumers are demanding that chemicals added during the treatment of drinking water be kept to a minimum. As a consequence, conventional clarification methods are being challenged to comply with the new regulations and restrictions and our understanding of the mechanisms involved is being tested as never before. Interface Science in Drinking Water Treatment contains a rigorous review of water treatment practices from a fundamental viewpoint. The book includes material from leading experts in the field of water treatment, reviewing their specific fields of expertise against a background of colloid and surface chemistry, and examines each step of the journey from source to consumer tap. It therefore permits the reader to develop a deep understanding of the complex processes taking place and of the necessary treatments which are vital for the provision of safe and palatable drinking water. The book is aimed at researchers, educators and practitioners in science and engineering, particularly those involved in water treatment and colloidal chemistry.

  • Handbook of Adhesives and Sealants

    General Knowledge, Application of Adhesives, New Curing Techniques
    • 1st Edition
    • Volume 2
    • Philippe Cognard
    • English
    Contributions from more than 60 authors, each a well-known specialist in their field, have been co-ordinated to produce the most comprehensive Handbook of Adhesives and Sealants ever published. The handbook will be published as 8 volumes, over a period of 4 years and will contain over 2800 pages, rich with case studies, industrial applications and the latest research. It is a work in progress, enabling the latest new and important applications to be included as they happen. Volume 2 of Elsevier’s Handbook of Adhesives & Sealants Series, General knowledge, application of adhesives & new curing techniques, covers the mechanisms of adhesion, its application, and drying and curing techniques. The volume is divided in to the following sections: • Theory of adhesion • Metering and dispensing • Design and calculation of bonded joints• Heat stable adhesives• UV curing • Flexible bonding and sealants Each contributing author is a scientist, practitioner, engineer, or chemist with an abundance of practical experience in their respective field, making this text an authoritative reference source for any materials scientist or engineer, whether in academia or industry.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 91
    • Alan R. Katritzky
    • English
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area - one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 58
    • Graham A. Webb
    • English
    Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has grown to such importance as NMR spectroscopy. It is used in all branches of science where precise structural determination is required and where the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy.

  • Pharmaceutical Manufacturing Encyclopedia, 3rd Edition Database

    • 3rd Edition
    • William Andrew William Andrew Publishing
    • English
    This industry standard database on pharmaceutical manufacturing processes has been completely updated to include FDA drugs approved up to the summer of 2004. The database gives details for the manufacture of 2226 pharmaceuticals that are being marketed as a trade-named product somewhere in the world. Each entry includes:ò Therapeutic function ò Chemical and common nameò Structural Formulaò Chemical Abstracts Registry no.ò Trade name, manufacturer, country, and year introducedò Raw Materialsò Manufacturing ProcessIn addition, references are also cited under each drug's entry to major pharmaceutical works where additional information can be obtained on synthesis and the pharmacology of the individual products. The database is for the Windows OS.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 57
    • Graham A. Webb
    • English
    Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has grown to such importance as NMR spectroscopy. It is used in all branches of science where precise structural determination is required and where the nature of interactions and reactions in solution is being studied. Annual Reports on NMR has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy.

  • Crystallography Made Crystal Clear

    A Guide for Users of Macromolecular Models
    • 3rd Edition
    • Gale Rhodes
    • English
    Crystallography Made Crystal Clear makes crystallography accessible to readers who have no prior knowledge of the field or its mathematical basis. This is the most comprehensive and concise reference for beginning Macromolecular crystallographers, written by a leading expert in the field. Rhodes' uses visual and geometric models to help readers understand the mathematics that form the basis of x-ray crystallography. He has invested a great deal of time and effort on World Wide Web tools for users of models, including beginning-level tutorials in molecular modeling on personal computers. Rhodes' personal CMCC Home Page also provides access to tools and links to resources discussed in the text. Most significantly, the final chapter introduces the reader to macromolecular modeling on personal computers-featuring SwissPdbViewer, a free, powerful modeling program now available for PC, Power Macintosh, and Unix computers. This updated and expanded new edition uses attractive four-color art, web tool access for further study, and concise language to explain the basis of X-ray crystallography, increasingly vital in today's research labs.

  • Fundamentals of Preparative and Nonlinear Chromatography

    • 2nd Edition
    • Georges Guiochon + 2 more
    • English
    Fundamentals of Preparative and Nonlinear Chromatography, Second Edition is devoted to the fundamentals of a new process of purification or extraction of chemicals or proteins widely used in the pharmaceutical industry and in preparative chromatography. This process permits the preparation of extremely pure compounds satisfying the requests of the US Food and Drug Administration. The book describes the fundamentals of thermodynamics, mass transfer kinetics, and flow through porous media that are relevant to chromatography. It presents the models used in chromatography and their solutions, discusses the applications made, describes the different processes used, their numerous applications, and the methods of optimization of the experimental conditions of this process.

  • Statistical Design - Chemometrics

    • 1st Edition
    • Volume 25
    • Roy E Bruns + 2 more
    • English
    Statistical Design-Chemometrics is applicable to researchers and professionals who wish to perform experiments in chemometrics and carry out analysis of the data in the most efficient way possible. The language is clear, direct and oriented towards real applications. The book provides 106 exercises with answers to accompany the study of theoretical principles. Forty two cases studies with real data are presented showing designs and the complete statistical analyses for problems in the areas chromatography, electroanalytical and electrochemistry, calibration, polymers, gas adsorption, semiconductors, food technology, biotechnology, photochemistry, catalysis, detergents and ceramics. These studies serve as a guide that the reader can use to perform correct data analyses.

  • Advances in Quantum Chemistry

    • 1st Edition
    • Volume 49
    • John R. Sabin + 1 more
    • English
    Advances in Quantum Chemistry presents surveys of current developments in this rapidly developing field that falls between the historically established areas of mathematics, physics, chemistry, and biology. With invited reviews written by leading international researchers, each presenting new results, it provides a single vehicle for following progress in this interdisciplinary area. This volume continues the tradition with high quality and thorough reviews of various aspects of quantum chemistry. It contains a variety of topics that include an extended and in depth discussion on the calculation of analytical first derivatives of the energy in a similarity transformed equation of motion couples cluster method.

  • Profiles of Drug Substances, Excipients and Related Methodology

    • 1st Edition
    • Volume 32
    • Harry G. Brittain
    • English
    Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions are now augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change meets the needs of the pharmaceutical community and allows the development of a timely vehicle for publishing review materials on this topic. While offering comprehensive and specialised chapters, Profiles of Drug Substances, Excipients and Related Methodology, Volume 32 also presents a methodology review article on the validation of chromatographic methods of analysis, as well as a summary of the publications in 2004 that dealt with polymorphism and solvatomorphism.

  • Chemistry and Biology of Heparin and Heparan Sulfate

    • 1st Edition
    • Hari G. Garg + 2 more
    • English
    The chemistry, biochemistry and pharmacology of heparin and heparan sulfate have been and continue to be a major scientific undertaking - heparin and its derivative remain important drugs in clinical practice. Chemistry and Biology of Heparin and Heparan Sulfate provides readers with an insight into the chemistry, biology and clinical applications of heparin and heparan sulfate and examines their function in various physiological and pathological conditions. Providing a wealth of useful information, no other tome covers the diversity of topics in the field. Students, doctors, chemists, biochemists, and research scientists will find this book an invaluable source for updating their current knowledge of developments in this area.

  • Landmark Papers in Clinical Chemistry

    • 1st Edition
    • Richard M. Rocco
    • English
    This is the first major review of the developments in clinical laboratory science in the 20th century presented in the words of the original inventors and discoverers. Introductory comments by the editor help place the works within the historical context.Landmark Papers addresses:*The origin of the home pregnancy test available today in every drugstore*The woman who invented a billion dollar technology, refused to patent it and went on to win a Nobel Prize*The scientists who worked on the US Government’s crash program at the start of WWII to find a substitute for the malaria drug quinine*The blood test used to monitor the effectiveness of cholesterol lowering drugs that today are taken by over 20 million patients*The graduate student who invented a technology for testing for infectious diseases, took it to Africa to screen people for malaria for the first time and which is now used to test for HIV infection world-wide*The invention of molecular diagnostics by Linus Pauling and the road to individualized medicine*The development of the glucose meter used by diabetics up to six times a day to monitor their metabolic control

  • The Encyclopedia of Mass Spectrometry

    Volume 3: Biological Applications Part B
    • 1st Edition
    • Richard Caprioli
    • English
    Volume 3 looks at classes of biomolecules including carbohydrates, nucleic acids, and lipids. In addition, special areas of application are included, such as pharmaceuticals, natural products, isotope ratio methods for biomolecules analysis, and clinical applications. The articles are arranged under general headings for continuity and ease of access, although several of these are of interest across the various disciplines. The articles are intended to teach and therefore strive to cover basics and sufficient additional detail to bring the reader up-to-date on a given subject. Some advanced topics are also covered, either in a special section of articles or in additional reading citations.

  • Quantum Chemistry

    • 3rd Edition
    • John P. Lowe + 1 more
    • English
    Lowe's new edition assumes little mathematical or physical sophistication and emphasizes an understanding of the techniques and results of quantum chemistry. It can serve as a primary text in quantum chemistry courses, and enables students and researchers to comprehend the current literature. This third edition has been thoroughly updated and includes numerous new exercises to facilitate self-study and solutions to selected exercises.

  • Contemporary Aspects of Boron: Chemistry and Biological Applications

    • 1st Edition
    • Volume 22
    • Hijazi Abu Ali + 2 more
    • English
    Contemporary Aspects of Boron: Chemistry and Biological Applications highlights the biological activity and applications of boron containing compounds. The authors’ specific approach surveys general features of the subject, while exploring new and novel strategies for preparing certain chemical and natural boron products that are of significant substance in medicinal chemistry. For example, cancer treatment is one of the most important issues related to such products. In addition to contributing to the development of new drugs by addressing biological applications in medicinal and industrial fields, the book provides a comprehensive review of the most relevant components that comprise the pharmaceutical, medicinal and environmental applications of boron containing compounds.

  • Handbook of Adhesives and Sealants

    Basic Concepts and High Tech Bonding
    • 1st Edition
    • Volume 1
    • Philippe Cognard
    • English
    Handbook of Adhesives and Sealants is the most comprehensive Adhesives and Sealants Handbook ever published, with the cooperation of around 35 authors from all over the world – each one a specialist in their field. It will include 80 chapters dealing with general information, theory of bonding and sealing, design of bonding parts, technical characteristics, chemistry, types of adhesives, application, equipment, controls, standards etc. Industrial applications such as automotive, aeronautics, building and civil engineering, electronics, packaging, wood, furniture, metals, plastics and composites, textiles, footwear etc.

  • Strategies and Tactics in Organic Synthesis

    • 1st Edition
    • Volume 6
    • Michael Harmata
    • English
    A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project. In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world.

  • Strategic Applications of Named Reactions in Organic Synthesis

    • 1st Edition
    • Laszlo Kurti + 1 more
    • English
    Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 54
    • Graham A. Webb
    • English
    Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has grown to such importance as NMR spectroscopy. It is used in all branches of science where precise structural determination is required and where the nature of interactions and reactions in solution is being studied. Annual Reports on NMR has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy.

  • Analytical Pyrolysis of Synthetic Organic Polymers

    • 1st Edition
    • Volume 25
    • Serban C. Moldoveanu
    • English
    Analytical Pyrolysis of Synthetic Organic Polymers is a follow-up to Analytical Pyrolysis of Natural Organic Polymers, which is volume 20 of the series. The main focus of the book is on practical applications of analytical pyrolysis in synthetic organic polymer identification and characterization. The first part of the book has five chapters including an introduction, a discussion on physico-chemistry of thermal degradation of synthetic polymers and on instrumentation used in analytical pyrolysis, a chapter discussing what type of information can be obtained from analytical pyrolysis, and a chapter dedicated to the analysis and characterization of synthetic polymers.The second part systematically covers the analytical pyrolysis of various classes of synthetic polymers. Some theoretical background for the understanding of polymer structure using analytical pyrolysis is also discussed.

  • Profiles of Drug Substances, Excipients and Related Methodology

    • 1st Edition
    • Volume 31
    • Harry G. Brittain
    • English
    Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions will now also be augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change is required to better meet the needs of the pharmaceutical communtiy and to allow the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series will encompass review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodologoy related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

  • Encyclopedia of Analytical Science

    • 2nd Edition
    • Paul J. Worsfold + 2 more
    • English
    As with the first edition of the Encyclopedia of Analytical Science, Second Edition is designed to provide a detailed and comprehensive publication covering all facets of the science and practice of analysis. The new work has been extensively revised in terms of the titles and content of the first edition, and includes comprehensive coverage of techniques used for the determination of specific elements, compounds and groups of compounds, in physical or biological matrices. It addresses applications of chemical analysis in all areas, ranging from such topics as medicine to environmental science, and geology to food science. Important characterisation techniques, such as microscopy and surface analysis are also included. The complete work consists of around 610 articles, each consisting of about 4000 words, figures and summary tables. These articles are combined to form larger entries providing comprehensive coverage of important topics and assisting the reader in locating material of interest. The entries are arranged in an A to Z format providing a final publication of about two and a half million words in ten volumes. The articles are structured to allow easy access to information on specific analytes, instrumental techniques and sample matrices. There is extensive cross-referencing throughout the Encyclopedia and a detailed index. Also available online via ScienceDirect – featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedire...

  • The Encyclopedia of Mass Spectrometry

    Volume 4: Fundamentals of and Applications to Organic (and Organometallic) Compounds
    • 1st Edition
    • Nico Nibbering
    • English
    Volume 4: Organic and Organometallic Compounds presents a cross section of applications in organic and organometallic chemistry in two parts. Chapters 1 to 6 are devoted to the fundamentals whereas chapters 7 and 8 cover applications to organic and organometallic compounds, either available as pure compounds or present in complex mixtures. Chapter 1 describes the theory for organic mass spectrometry, building on and complementing material in Volume 1. The themes for Chapter 2 are the structures and properties of gas-phase ions of conventional, distonic, and non-covalent complexes. Chapter 3 covers methodology used in study of gas-phase ions. Chapters 4 and 5 turn to mechanisms of both unimolecular and bimolecular reactions of ions and include topics in stereochemistry and radical chemistry. Chapter 6 contains a number of articles on the formation and reactivity of metal ion complexes and organometallic cations and anions, drawing connections with molecular recognition, catalysis and organic synthesis. Chapter 7 deals with the structure determination of organic compounds, including chiral compounds and natural products. In chapter 8 are contributions that provide illustrative examples of the determination of organic compounds present at low levels in complex samples that originate from various natural and biological sources. Included is an article on the determination of explosives.

  • Nitrosation Reactions and the Chemistry of Nitric Oxide

    • 1st Edition
    • D.L.H. Williams
    • English
    Since 1988, there has been much literature published on the chemistry of nitric oxide, particularly in the field of S-nitrosation and the chemistry of S-nitroso compounds. Written by a chemist for the chemistry community, this book provides an update of the chemistry of nitrosation reactions, dealing with both the synthetic and mechanistic aspects of these reactions. It also looks at the chemistry of nitric oxide in relation to the amazing biological properties of this simple diatomic molecule, which were unknown until around 1990.

  • The Encyclopedia of Mass Spectrometry

    Volume 2: Biological Applications Part A
    • 1st Edition
    • Richard Caprioli + 1 more
    • English
    The focus of Volume 2 of the Encyclopedia of Mass Spectrometry is on peptides and proteins, separation techniques, preparation protocols, and the fundamental characteristics as ionic gas phase species that lie within the breadth of the field of mass spectrometry. This volume is divided into four sections; experimental approaches and protocols, sequence analysis, other structural analyses, and targeted applications.

  • Molecular Diversity and Combinatorial Chemistry

    Principles and Applications
    • 1st Edition
    • Volume 24
    • Michael C. Pirrung
    • English
    The field of combinatorial chemistry has seen tremendous growth over the past decade, with a prominence that suggests it will have a continuing impact. Volume 24 in the Tetrahedron Organic Chemistry Series represents new approaches to solving problems in chemical reactivity and function. Molecular Diversity and Combinatorial Chemistry emphasises principles and exemplifies these with examples drawn from recent literature and thus is an excellent guide to the conceptual framework of the field. The textbook includes exercises and worked problems which can provide more independent learning experiences and can also be used by an instructor leading a class on this topic. This volume has been written with the advanced undergraduate and graduate student in mind.

  • Molecular Diversity and Combinatorial Chemistry

    Principles and Applications
    • 1st Edition
    • Volume 24
    • Michael C. Pirrung
    • English
    The field of combinatorial chemistry has seen tremendous growth over the past decade, with a prominence that suggests it will have a continuing impact. Volume 24 in the Tetrahedron Organic Chemistry Series represents new approaches to solving problems in chemical reactivity and function. Molecular Diversity and Combinatorial Chemistry emphasises principles and exemplifies these with examples drawn from recent literature and thus is an excellent guide to the conceptual framework of the field. The textbook includes exercises and worked problems which can provide more independent learning experiences and can also be used by an instructor leading a class on this topic. This volume has been written with the advanced undergraduate and graduate student in mind.

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