The Encyclopedia of Mass Spectrometry
Volume 3: Biological Applications Part B
- 1st Edition - November 11, 2005
- Latest edition
- Editor: Richard Caprioli
- Language: English
- Hardback ISBN:9 7 8 - 0 - 0 8 - 0 4 3 8 0 3 - 0
- eBook ISBN:9 7 8 - 0 - 0 8 - 0 9 1 3 2 0 - 9
Volume 3 looks at classes of biomolecules including carbohydrates, nucleic acids, and lipids. In addition, special areas of application are included, such as pharmaceuticals,… Read more
Volume 3 looks at classes of biomolecules including carbohydrates, nucleic acids, and lipids. In addition, special areas of application are included, such as pharmaceuticals, natural products, isotope ratio methods for biomolecules analysis, and clinical applications. The articles are arranged under general headings for continuity and ease of access, although several of these are of interest across the various disciplines. The articles are intended to teach and therefore strive to cover basics and sufficient additional detail to bring the reader up-to-date on a given subject. Some advanced topics are also covered, either in a special section of articles or in additional reading citations.
- Covers the major classes of biomolecules including carbohydrates, nucleic acids, and lipids
- Includes special areas of application, such as pharmaceuticals, natural products, isotope ratio methods for biomolecules analysis, and clinical applications
- Written for students entering the field of mass spectrometry
Advanced Research Scientists; Mass Spectrometrists; Spectroscopists; Analytical Chemists; and those working in these fields
Volume 3: Applications to Biology, Carbohydrates, Nucleic Acids, and other Biological Compounds
Chapter 1: Nucleic Acids
Nucleic Acids: DNA and RNA Sequence Analysis
Nucleic Acids: RNA Mapping
Nucleic Acids: Base Analysis
Enzymatic digestion of nucleic acids
Desorption ionization of nucleosides and nucleotides
Nucleic Acids: Analysis of DNA Single Nucleotide Polymorphisms
Nucleic Acids: DNA - ligand complexes
DNA adducts
Nucleic Acids: High Throughput Genotyping of Short Tandem Repeat DNA Markers
Modified nucleosides in RNA and human urine
Characterization of Noncovalent Complexes of Nucleic Acids and Proteins by Electrospray Ionization
Chapter 2: Saccharides
GC/MS of Derivatised Carbohydrates
LC/MS of carbohydrates from glycoproteins
MALDI MS of Carbohydrates
Carbohydrates: Digestion of Glycoprotein Carbohydrates for Glycosylation Analysis
Structural elucidation of O-linked oligosaccharides
Chapter 3: Pharmacology/Toxicology
GC-MS of Drugs and Metabolites
LC/MS of Drugs and Metabolites
Structure Determination - Natural
Drug Disposition
Combinatorial Library Screening using Mass Spectrometry
the Role of Oxidative Stress in Cancer and Toxicology
Accelerator Mass Spectrometry
Chapter 4: Natural Products
Natural products extracted from plants
Natural Products: Protein Identification in Microorganisms
Applications to olive oil, wine and food from a nutritional aspect
Chapter 5: Isotope Ratio
Quantitative analysis of biological samples
Isotope Ratio in Biology: Stable Isotopes to Measure In Vivo Metabolism and Kinetics Using Mass Spectrometry
Mass Spectrometry to Measure In Vivo Glucose Metabolism Using Stable Isotope Labels
Isotope ratio mass spectrometry in human biology: amino acid metabolism and kinetics
DNA synthesis rates measured using stable isotopes
Stable isotope breath tests
Isotope Ratio in Biology: CRIMS
Chapter 6: Lipids
Structural analysis of free fatty acids and triacylglycerols
Analysis of phospholipids by electrospray mass spectrometry
Analysis of sphingomyelins
Steroid Analysis
Analysis of sulfatides
Analysis of prostaglandins and metabolites by mass spectrometry
Analysis of leukotriene and lipoxygenase products by electrospray mass spectrometry
Isoprostanes and Related Products of Lipid Peroxidation: Characterization and Quantification by Mass Spectrometry
Chapter 7: Clinical Applications
Metabolite profiling in urine and blood for the diagnosis of metabolic disorders
Serum and plasma profiling
Clinical Applications: Hemoglobin Variants
- Edition: 1
- Latest edition
- Published: November 11, 2005
- Language: English
RC
Richard Caprioli
Biography Richard M. Caprioli is the Stanley Cohen Professor of Biochemistry and Director of the Mass Spectrometry Research Center at Vanderbilt University School of Medicine. He is also currently Professor in the Departments of Chemistry and Pharmacology at Vanderbilt.
Affiliations and expertise
Vanderbilt University School of Medicine, Nashville, USA