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Elsevier

Books in Life sciences

  • The Renaissance in GPCR Research and Drug Discovery

    Receptor Function, Receptor Structure, New Techniques, and Characterization of Drug Activity
    • 1st Edition
    • Terry P. Kenakin
    • English
    The Renaissance in GPCR Research and Drug Discovery: Receptor Function, Receptor Structure, New Techniques, Characterization of Drug Activity, Drug Discovery is a comprehensive reference for pharmacology researchers. It focuses on utilizing novel aspects of GPCR function for therapeutic advantage and applying new chemical types to modify GPCR behavior. Recent advancements have revitalized GPCR discovery, opening unexplored avenues for new drug development. The book's content is meticulously divided into five distinct parts, covering evolutionary perspectives, novel functions, investigative technologies, therapeutic modalities, and a broad range of GPCR ligands.Beyond these key topics, the book delves into the evolution of GPCRs as drug targets, the mechanisms behind their novel functions, and the latest technologies driving research and discovery. It also highlights new and recently approved therapeutic modalities and provides a broad coverage of GPCR ligands. Edited and authored by leading researchers, this book serves as an essential reference for drug discovery researchers and medicinal chemists, as well as AI researchers exploring this drug discovery space.

  • Postharvest Loss and Waste Management of Horticultural Produce

    From Farm to Fork
    • 1st Edition
    • Zahra H. Mohammad + 2 more
    • English
    Postharvest Loss and Waste Management of Horticultural Produce: From Farm to Fork addresses the major challenges and root causes of postharvest losses while also presenting solutions to reduce losses using innovative technologies. Sections introduce an overview of postharvest challenges, such as postharvest handling, storage, and transportation of fruits, vegetables, and berries, along with the impact of COVID-19 on postharvest losses. Other sections cover postharvest biological issues and control, such as postharvest diseases and microbiology issues of produce, novel technologies for reducing postharvest loss and waste in horticulture, like biological control, packaging, MAP films, etc., and mitigation strategies. A final section explores the environmental, economic, and social impact of postharvest losses across the food supply chain. Edited by a team of experts in the field, this is an excellent resource that brings sustainable solutions to reduce postharvest losses on a global level. Attracting a wider audience in the fields of food engineering and technology, as well as professionals, researchers, and academicians working in the fields of postharvest losses and their management, this book will be a welcomed resource.

  • Novel Plant Proteins as Mainstream Ingredients for Future Foods

    • 1st Edition
    • Khetan Shevkani
    • English
    Novel Plant Proteins as Mainstream Ingredients for Future Foods addresses the techno-functionality... health benefits, and sustainability of alternative proteins from familiar plant sources such as quinoa and other pseudocereals, rice bran, and hempseeds, along with more novel sources such as nigella seeds, fenugreek, moringa leaves, and the aquatic plant duckweed. The book provides a concise overview of the techno-functional, nutritional, and nutraceutical properties of these proteins that are essential for their application in functional foods, dietary supplements, and in the creation of healthier foods. Sections discuss advanced processing technologies capable of overcoming the limitations of conventional protein extraction methods and highlight the composition and nutritional value of fruits and vegetable by-products, elaborating on the quality and techno-functionality of fruit and vegetable seed protein isolates to critically examine their adoption by the food industry. The book concludes by analyzing the challenges associated with plant proteins such as allergens, antinutrient presence, compositional inconsistencies, poor nutritional quality compared to animal proteins, and undesirable sensory effects, along with promising solutions to enhance future applications.

  • Clinical Atlas of Gonioscopy

    • 1st Edition
    • Chunyan Qiao + 3 more
    • English
    Clinical Atlas of Gonioscopy comprehensively and systematically covers all aspects of gonioscopy: from basic knowledge and common manifestations to characteristic signs of different diseases, and the application of gonioscopy in the laser and surgical treatment of glaucoma. Including over a thousand high-quality images, it helps clinicians explore the diverse and fascinating world of the anterior chamber angle, and deepens their understanding of the pathogenesis, classification, diagnosis, differential diagnosis, treatment and follow-ups of glaucoma.

  • Plant-Based Proteins in Food Processing and Production

    • 1st Edition
    • Claire Darizu Munialo
    • English
    Plant-Based Proteins in Food Processing and Production addresses the urgent global challenge of climate change by exploring sustainable alternatives to animal-derived proteins. With growing concerns about the environmental impact of food production, this book provides a timely and comprehensive examination of plant-based proteins, focusing on their potential to reduce greenhouse gas emissions while meeting nutritional and functional food requirements. The book offers an in-depth exploration of plant-based alternative proteins through four key sections. The first section covers a variety of plant protein sources, including soy, pea, oil-producing plants, seaweed, and novel emerging proteins. The second section focuses on the processing techniques, such as extraction, modification, and innovative technologies for producing plant-based meat alternatives. The third section examines practical applications, including plant-based alternatives to milk, meat, egg, and fat replacers, as well as the role of protein blends in product formulation. Finally, the book addresses challenges and opportunities related to sensory qualities, consumer acceptance, sustainability, and future prospects in plant-based food production.Plant-Bas... Proteins in Food Processing and Production is an essential resource for professional food scientists in the engineering and manufacturing of plant-based protein products, as well as graduate students and researchers in food science and technology. By combining scientific insight with practical applications, this book equips readers with the knowledge needed to innovate and advance sustainable protein solutions, supporting the evolution of the global food industry toward a more environmentally responsible future.

  • Intelligent IoT-based Diagnostic and Assistive Systems for Neurological Disorders

    • 1st Edition
    • Hanif Heidari + 1 more
    • English
    Intelligent IoT-based Diagnostic and Assistive Systems for Neurological Disorders discusses the latest developed methods in IoT and its applications in neurological disorders that emphasize end-user requirements. Intelligent IoT is used to explore the intersection between medicine, data science, biomedical engineering, and healthcare systems. A comprehensive overview of modelling and analyzing the requirements of people with neurological disorders is presented in this book. Signals and images of biological activity are collected and analyzed based on patient specifications to facilitate more accurate diagnosis and treatment. The book also discusses cutting-edge AI methods for IoT devices designed to treat neurological conditions.

  • Wood-Water Interactions

    • 1st Edition
    • Samuel L. Zelinka + 3 more
    • English
    Wood-Water Interactions examines the complex relationship between wood and water using an intuitive approach to what has historically been treated as an opaque and demanding field of study. Wood-moisture interactions dominate nearly every facet of wood technology and utilization, yet new findings continue to change our understanding of this topic. Authored by experts in the field, the chapters follow a logical structure and include case studies with vivid illustrations. Readers are motivated to understand updated information about the interaction of water with wood, the effect of changes in moisture content on the properties of wood and wood-based materials as well as the latest research methods used to study wood-water interactions.

  • Combinatorial Biotechnology

    Methods for Synthesis of Peptide, Oligonucleotide and Oligosaccharide Libraries and Applications
    • 1st Edition
    • Preeti Srivastava
    • English
    Combinatorial Biotechnology: Methods for Synthesis of Peptide, Oligonucleotide and Oligosaccharide Libraries and Applications covers methods used for synthesizing peptide, oligonucleotide, and oligosaccharide libraries. It presents the concepts of combinatorial biotechnology, detailing both solid phase and solution phase synthesis techniques, including modern biological methods such as in vitro and in vivo display libraries. Key topics include solid phase synthesis, parallel peptide synthesis, encoding technologies, deconvolution methods, and chemical and biological ligations. With chapters covering the chemical and biological synthesis of recombinant peptides and proteins, as well as the genetic reprogramming of the genetic code, this book offers a rich source of practical guidance.The inclusion of advanced methods and illustrative examples makes it a unique and essential reference in the field. This book is an essential resource for undergraduate and postgraduate students in biochemical engineering, biotechnology, and biosciences, as well as industry professionals in R&D divisions. It equips readers with the latest techniques and applications in combinatorial biotechnology, addressing current challenges and advancing their research and development efforts.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 135
    • English
    Advances in Applied Microbiology, Volume 133 presents a comprehensive exploration of the latest innovations in applied microbiology. The book delves into the diverse applications of microbiology across various industries, including agriculture, food production, biotechnology, environmental science, and healthcare. Chapters in this new release include Advances in production related petroleum microbiology, Degradation of Steroid Four-Ring Structures by Comamonas testosteroni: Similar Mechanisms Observed in Various Bacteria Including Mycobacterium tuberculosis, Detoxification of mycotoxins by microorganisms, Use of Deep Eutectic Solvents in Microbial Technology, and more.Through a collection of insightful chapters authored by experts in the field, readers are offered in-depth analyses of cutting-edge research, emerging trends, and practical applications of microbiological principles. From novel microbial technologies to the impact of microbiomes on human health and beyond, this book serves as a valuable resource for researchers, professionals, and students seeking to stay informed and inspired by the exciting advancements.

  • AI-Driven Diagnostics for 6G-Enabled Smart Healthcare

    • 1st Edition
    • Sangeeta Kumari + 3 more
    • English
    AI-Driven Diagnostics for 6G-Enabled Smart Healthcare explores the transformative integration of artificial intelligence (AI) and next-generation 6G networks in the healthcare sector. The book begins by highlighting the evolution of healthcare technology and the critical role of AI-driven diagnostics, emphasizing how 6G facilitates real-time, ultra-reliable communication. Key features of 6G, such as ultra-low latency and massive connectivity are discussed, showcasing their impact on advanced healthcare applications like remote diagnostics and patient monitoring. In addition, the integration of AI in medical diagnostics is examined, focusing on machine learning and deep learning techniques that enhance disease detection through medical imaging and clinical data analysis.Users will also find content that explores the benefits of remote patient monitoring, particularly for underserved populations, and delves into edge AI for localized, low-latency diagnostic processing. Other sections cover real-time imaging diagnostics are highlighted and address predictive analytics, detailing AI models that forecast diseases and the role of IoT devices and wearables in healthcare diagnostics. Final sections cover ethical considerations and regulatory challenges.

  • Cranial Nerve Compression Syndromes

    A Multidisciplinary Guide to Management
    • 1st Edition
    • Florian Roser + 1 more
    • English
    Cranial Nerve Compression Syndromes: A Multidisciplinary Guide to Management is a comprehensive volume exploring the entire pathophysiology of cranial nerve pathologies, from diagnosis to treatment options. Following a multidisciplinary approach, this volume integrates perspectives from neurosurgery, neurology, radiology, and pain management from experts in the field. An ideal resource for clinicians and researchers, this volume discusses the latest research on multi-modality, collaborative, and cutting-edge treatment options, with advanced surgical techniques, including microvascular decompression and endoscopic procedures with clear guidance.

  • Natural Food Colorants

    Chemistry, Health Aspects, and Industrial Applications
    • 1st Edition
    • Mohamed Fawzy Ramadan + 2 more
    • English
    Natural Food Colorants: Chemistry, Health Aspects and Industrial Applications is a comprehensive resource designed for food scientists, food technologists, and food chemists interested in the use of sustainable food colorants for product development, functional foods, and nutraceuticals. The volume is divided into three comprehensive sections that offer readers an in-depth exploration of the chemistry and functionality of various natural pigments, including anthocyanins, carotenoids, betalains, and chlorophylls. Emphasizing innovative extraction techniques, the book highlights methods that enhance yield and stability, paving the way for the development of healthier functional foods devoid of harmful additives.Further sections address critical themes of sustainability, environmental impact, and regulatory considerations, providing a holistic view of the industry landscape. With 15 chapters written by a global team of experts, readers will encounter topics ranging from food colorant diversity and classification—such as brown algae, licorice, phycocyanin, and anthocyanidin—to specific applications of colorants in various industries.

  • Vegan Food Products

    Sources, Production Methods, Challenges and Improvement Strategies
    • 1st Edition
    • Tuba Esatbeyoglu + 1 more
    • English
    Vegan Food Products: Sources, Production Methods, Challenges and Improvement Strategies assembles the science related to different vegan foods in a comprehensive reference that discusses the benefits and challenges of vegan food products. Comprised of 11 chapters, the book covers the vegan alternatives of different food groups, including meat, fish, egg, and dairy. It also presents a variety of vegan protein sources, such as plant-based proteins, macro- and microalgae and single-cell proteins. Sections explore production methods and technologies, including extrusion, dry-fractionation methods for enriching proteins, 3D printing, and in vitro methods. In addition, the health aspects of vegan foods, with a specific chapter devoted to the fortification studies, are covered, as well as the vegan food market, the consumer perception, and the sensory and nutritional quality of vegan products. Edited by well-known global researchers in the field, this book provides readers with a broad review of the most recent research on the opportunities and challenges of vegan ingredients and foods.

  • Bioactives from Aquatic Side Streams

    Innovative Extraction Procedures and Applications
    • 1st Edition
    • Sakhi Ghelichi + 2 more
    • English
    Bioactives from Aquatic Side Streams: Innovative Extraction Procedures and Applications examines the untapped potential of aquatic resources and byproducts as a rich source of bioactive compounds, including proteins and peptides, omega-3 fatty acids, phenolic compounds, pigments, vitamins, and minerals. With a focus on sustainable practices, this book explores the identification, extraction, characterization, and application of these bioactive compounds across various industries. Early chapters characterize the bioactivity of key compounds, describe the aquatic side streams available for sourcing these compounds, and provide a high-level overview of their extraction techniques.Central chapters focus on these processes for specific bioactive compounds, including hydrolysates, peptides, omega-3 oil, phospholipids, collagen, gelatin, chitin, chitosan, minerals, pigments, and more. Concluding chapters explore emerging techniques, market hurdles and possible solutions, and regulatory considerations for the sustainable sourcing of bioactive compounds from aquatic side streams. By equipping readers with the knowledge to develop new products that enhance existing ones, this book promotes the innovative use of aquatic byproducts for a more sustainable future.

  • Bioactive Compounds in Leaves of Bulbs, Roots, and Tubers

    A Food Chemistry Approach to Nutritional, Biological, and Pharmaceutical Applications
    • 1st Edition
    • Neela Satheesh + 1 more
    • English
    Bioactive Compounds in Leaves of Bulbs, Roots, and Tubers: A Food Chemistry Approach to Nutritional, Biological, and Pharmaceutical Applications offers a crucial resource for researchers and industry professionals aiming to harness underutilized plant parts for health and sustainability. Despite their rich phytochemical profiles and potential health benefits, these leaves remain largely unexplored, representing a missed opportunity for functional food development, nutraceuticals, and pharmaceuticals. This book bridges that knowledge gap by providing detailed insights into their chemical composition, bioactive properties, and innovative extraction methods, promoting their integration into food and medicine. It covers an extensive range of topics, including phytochemical profiling, nutritional and anti-nutritional analysis, green extraction technologies, and applications of bioactive compounds from turmeric, sweet potato, carrot, cassava, radish, turnip, kohlrabi, sugar beet, yam, taro, ginger, onion, garlic, and potato leaves. Additionally, it discusses safety, regulatory frameworks, and the potential use of these leaves as nutraceuticals, functional foods, and even animal feed, highlighting their significance for health and environmental sustainability. Bioactive Compounds in Leaves of Bulbs, Roots, and Tubers serves as an essential reference for advancing research, innovation, and sustainable utilization of these bioresources to improve human health, reduce waste, and promote eco-friendly food and pharmaceutical solutions.

  • Foundations of Antiviral Research and African Ethnomedicinal Knowledge

    • 1st Edition
    • Volume 120
    • English
    Advances in Botanical Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Practice of Neurocritical Care in Resource Limited Countries

    • 1st Edition
    • Hemanshu Prabhakar + 2 more
    • English
    Practice of Neurocritical Care in Resource Limited Countries offers a comprehensive examination of the unique challenges and practical strategies for delivering neurocritical care in low- and middle-income countries (LMICs). As the prevalence of neurological emergencies continues to rise in these regions, this book addresses the critical need for effective management in resource constrained environments. It begins by exploring the landscape of neurocritical care, including common neurological emergencies and their epidemiology in LMICs. The content outlines foundational principles of patient assessment and monitoring, as well as advanced management strategies for conditions such as traumatic brain injury, stroke, and spinal cord injury. Special attention is given to the nuances of caring for diverse patient populations, including pediatric and geriatric patients. Additionally, this book highlights the essential role of pain management, and nutritional support, in neurocritical settings. With contributions from experts across various LMICs, this resource emphasizes innovative approaches to training and capacity building, empowering healthcare professionals to provide high-quality neurocritical care despite the challenges of limited resources. This book is an invaluable tool for clinicians and educators dedicated to improving outcomes for neurologically ill patients in lesser-resourced healthcare systems.

  • Machine Learning and AI Technology for Agricultural Applications

    • 1st Edition
    • Kishore Chandra Swain + 5 more
    • English
    Feeding a growing global population with a changing climate, shrinking arable land, and increasingly strained water resources is a challenge with no single solution. Machine Learning and AI Technology in Agricultural Applications recasts agriculture as fundamentally a problem of data acquisition, integration, and analysis. Drawing on concrete methods and case studies, the book shows how advanced technologies turn scattered sensor readings, satellite imagery, and field records into decision-making tools that enable more precise, more resilient, and more sustainable farming practices.The chapters cover the full agricultural cycle: crop and weather indicators feeding models that predict yield before harvest; satellites and drones replacing manual field-monitoring surveys across the growing season; and image-based algorithms supporting targeted interventions, from detecting a diseased plant to directing a sprayer to apply treatment only where it is required. The same reliance on remote sensing and predictive modeling carries into aquaculture and water management, where artificial intelligence (AI) and machine learning (ML) are used to estimate groundwater recharge, track fish growth, and monitor water quality. A dedicated set of chapters also examines the economic dimensions of this shift, assessing the viability, market impact, and costs of adopting these innovations, and clarifying where they are most likely to reshape how these sectors operate.Together, these technical perspectives make the book a valuable resource for students building a foundation in this field, as well as for researchers and practitioners looking to apply its findings and insights to their own work.

  • Blue Biotechnology

    Expanding Horizons with Marine Resources
    • 1st Edition
    • Marco F.L. Lemos + 1 more
    • English
    Blue Biotechnology showcases the latest findings and technological advancements in the areas of marine biology, genomics, bioengineering, and bioinformatics. The field of marine biotechnology, which involves the use of marine organisms and resources for biotechnological applications, encompasses a wide range of disciplines and has important implications for sustainable development, marine conservation, and economic growth. By presenting the most up-to-date and groundbreaking work, this book helps audiences stay abreast of this rapidly evolving field and inspires researchers to push the boundaries of biotechnological advancements. Written by leading experts in the field, this book brings together diverse perspectives, identifies research gaps, and generates new ideas. Early chapters introduce the field of marine biotechnology, illustrate the breadth of marine diversity and resources, and discuss methods and techniques for marine bioprospecting. Central chapters systematically discuss biotechnological applications in aquaculture and agriculture, food and nutrition, industry, medicine, and environmental remediation. Final chapters turn to the future and discuss the field’s applications to marine conservation, climate change adaptation, energy transition, as well as trends in industry scale-up, policy, challenges, and opportunities. Blue Biotechnology highlights the potential of marine biotechnology to help policymakers, government agencies, and industry leaders make informed decisions and contribute to the development of policies that support responsible and sustainable use of marine resources, while also fostering economic growth and environmental stewardship. It is an indispensable resource for researchers, industry scientists, stakeholders, policymakers, government employees, and students alike.

  • Gestational Diabetes Mellitus

    Epidemiology, Clinical Practice and Evidence-Based Guidelines
    • 1st Edition
    • Moshe Hod + 6 more
    • English
    Gestational Diabetes Mellitus: Epidemiology, Clinical Practice and Evidence-Based Guidelines is an invaluable resource for healthcare professionals seeking to understand the latest developments in GDM. Over the past 20 years, significant progress has been made in the study of its epidemiology, mechanisms, diagnosis, management, and prevention. This book delves into these advancements, offering insights that are crucial for both researchers and clinicians. It explores potential therapeutic solutions to enhance patient care, and is essential reading for obstetricians, endocrinologists, diabetes researchers, maternal health specialists, and pediatric endocrinologists, as well as specialty fellows, residents, postdoctoral fellows, and graduate students in these fields.

  • Biomedical Basis of Human Disease

    From Research to Clinic
    • 1st Edition
    • Ahmed El-Hashash + 3 more
    • English
    Biomedical Basis of Human Disease: From Research to Clinic provides information on pathophysiology/mech... of organ system disease and selected disorders and diseases that cause the most deaths worldwide, including but not limited to cardiovascular, respiratory, gastrointestinal and nervous systems. This information is placed within the structural context of tissue/organ, molecular and cellular biology, pathophysiology, diagnostic and treatment methods, and disease models in sections that also describe recent research examples, such as recently developed cutting-edge in vitro and in vivo biomedical science methods to bridge the bench and bedside. This text is suitable for students, researchers and practitioners in biomedicine and basic medicine.

  • Cultured Meat Production

    Advances, Challenges and Opportunities
    • 1st Edition
    • Zuhaib F. Bhat + 1 more
    • English
    Cultured Meat Production: Advances, Challenges and Opportunities discusses technologies in this exciting field, along with the feasibility of commercial production of fully structured cultured meat and seafood. In addition to covering the latest science, the book examines consumer perception, religious and cultural considerations, and regulatory aspects, such as quality assurance and food safety. The book's chapters are written by academic and industry experts from around the world at the forefront of this exciting field. Researchers, entrepreneurs, and advanced student audiences who are interested in getting up-to-speed on lab-grown meat won't want to miss this timely book.The ever-expanding human population calls for novel ways to produce protein of sufficient quality and quantity, however finite animal and land resources and increasing environmental concerns are already beginning to limit our capacity to produce an adequate protein supply. Novel technologies now allow for the production of cultured meat and seafood, offering a potentially lower carbon footprint and substantially eliminating animal suffering.

  • Precision Oncology in Liver Cancer

    Genomics, Infection, and the Exposome in African and Global Contexts
    • 1st Edition
    • Zodwa Dlamini
    • English
    Precision Oncology in Liver Cancer: Genomics, Infection, and the Exposome in African and Global Contexts explores liver cancer through the lens of precision medicine, integrating molecular profiling, environmental exposures, and targeted therapies. The book presents a multidisciplinary approach, covering infectious drivers like HBV/HCV, environmental carcinogens such as aflatoxins, and emerging tools including genomics, AI, and liquid biopsies. It emphasizes African-specific challenges and innovations, with case studies and comparative global insights. This volume equips researchers, clinicians, and policymakers with evidence-based strategies to address liver cancer disparities, offering a forward-looking framework for equitable cancer care and research in Africa and globally.

  • The Vitamins

    Fundamental Aspects in Nutrition and Health
    • 7th Edition
    • Gerald F. Combs Jr. + 1 more
    • English
    The Vitamins: Fundamental Aspects in Nutrition and Health, Seventh Edition presents both overviews and in-depth discussions of the sources, chemistry, metabolism, and functions of these essential nutrients in physiology and health. Further building upon previous editions of this widely used reference text, readers will gain updated information on the inclusion and interpretation of recent clinical research findings relevant to all vitamins, particularly Vitamins A, D, E, K, C, thiamin, folate and Vitamin B12. The latest information on nutritional deficiencies and ecological approaches to dealing with them along with a section on vitamin-drug interactions is also included.Readers will also find a revised table of signs of vitamin deficiencies in humans and animals, updated information on the roles of the gut microbiome in vitamin synthesis and metabolism, increased focus on vitamins as nutritional supplements, increased focus on vitamin stabilities in foods, including processing and cooking losses and a decision tree addressing the question: “Could I benefit from a vitamin supplement?.” At the end of each chapter, case studies, a quiz, and recommended reading list are included.

  • Functional Foods and Nutraceuticals of Fungal Origin

    Current Developments and Concepts
    • 1st Edition
    • Pragya Tiwari + 1 more
    • English
    Functional Foods and Nutraceuticals of Fungal Origin: Current Developments and Concepts discusses recent topics and relevant developments in the production of functional foods and nutraceuticals of fungal origin, along with their production technologies, nutritional components, health benefits, socioeconomic relevance, and potential for translational commercialization. The book's chapters include novel products, processes, and techniques such as microbial enzyme technologies, the use of native microbes, and renewable source of substrates and microbial engineering in the development of nutraceuticals. Omics technologies and their applications in edible fungi research and artificial intelligence-based prediction of bioactive compounds are also discussed. The book provides strategies and tools for the identification and analysis of fungi-based products while also exploring fungal pigments and colorants as food ingredients. Safety and regulatory aspects of fungal-derived food products and research innovation across the globe are also thoroughly explored. This book serves as a reference for food microbiologists, food scientists, and pharmaceutical professionals on the development of new functional foods and nutraceuticals.

  • Pediatric Substance Exposure

    • 1st Edition
    • Ju Lee Oei
    • English
    Pediatric Substance Exposure is a crucial resource for medical practitioners focusing on the long-term management of children exposed to addictive substances during pregnancy. It provides guidance on supporting families affected by substance abuse, starting with a comprehensive overview of epidemiology and global policy. The book examines various substances and their impact on children, discussing fetal management, infant and child care, and addressing family needs as the child grows. Beyond the basics, the book reviews social aspects, future research, and policy needs. Clinicians and researchers will find it invaluable for evidence-based decision-making and optimal treatment strategies.

  • Kefir

    Properties, Functionality, and Health Benefits
    • 1st Edition
    • Carlos Adam Conte Junior + 1 more
    • English
    Kefir: Properties, Functionality, and Health Benefits covers the more practical side of kefir production, technology, and product development. It focuses on the scientifically demonstrated benefits of this beverage, especially antimicrobial and antioxidant effects, intestinal microbiota modulation, immune response modulation, and anticancer properties. Bioactive compounds responsible for these effects are also explored to provide a theoretical basis for developing new food and pharmaceutical formulations. In addition, the book covers kefir’s potential role in neurodegenerative disease prevention. Finally, the readers will find strategies for product diversification, quality control, and biotechnological applications.Kefir is a fermented milk beverage that is growing in popularity among both researchers and consumers for its proven and potential health benefits. Companies interested in developing new fermented beverage products will find this work of interest.

  • Anti-Obesity Drug Development

    Physiology, Pharmacology and Drug Delivery
    • 1st Edition
    • Fadia Salah Youssef + 1 more
    • English
    Anti-Obesity Drug Development: Physiology, Pharmacology and Drug Delivery is a complete reference for pharmaceutical researchers in this key area of research and clinical development. The contents of the book are organized in four parts. The first provides an overview of the foundations and historical development of anti-obesity drugs, including extensive discussion of comorbidities and how they impact drug activity and efficacy. Part two is dedicated to the drug targets involved in the progression of obesity treatment. These include GLPRI and GIPR agonists, Incretin/Glucagon, RM-493 and Liraglutide, Pramlintide and metreleptin, Growth Hormone, FXR and GPR131, and the Gut Microbiota. Part three discusses the most common drugs available in the market and their pharmacological parameters. The final part of the book covers all natural products known to have scientific evidence on the treatment of obesity.Anti-Obesity Drug Development: Physiology, Pharmacology and Drug Delivery is the perfect reference for pharmacology researchers and those involved in new drug development both in academic and corporate environments. Research-physicians, endocrinologists, and nutritionists will also benefit from the comprehensive overview of treatments covered in this book.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 65
    • English
    Progress in Medicinal Chemistry, Volume 65 brings together state-of-the-art reviews and critical insights from leading scientists in the field. Each volume surveys the latest advances in drug discovery and development, with a focus on practical strategies, novel modalities, and real-world case studies. From target identification and structure-based design to optimization of pharmacokinetic properties, safety assessment, and translational science, these volumes provide a comprehensive, up-to-date overview for researchers, graduate students, and professionals working in medicinal chemistry, pharmacology, and related life sciences.Chapters in this new release cover Molecular Glues and Tactics in Hit Finding through to Lead Generation in Drug Discovery – current position and future directions.

  • Cellular Therapies for Cancer Treatment

    Advancements in Drug Delivery Strategies
    • 1st Edition
    • Arun Kumar Singh + 3 more
    • English
    Cellular Therapies for Cancer Treatment: Advancements in Drug Delivery Strategies explores the innovative use of cellular therapy to combat cancer, placing an emphasis on state-of-the-art delivery approaches. By covering a variety of cellular therapies for cancer, such as stem cells, immune cells, and others, this book provides a comprehensive introduction to the field. It describes ways to deliver drugs that target cancer cells more efficiently, decrease off-target effects, and enhance therapy outcomes. Sections provide a brief overview of cancer cell biology, describe the need for advance drug delivery systems, and address challenges and future directions.The book also goes into the ideas behind cellular therapies and how they may overcome drug resistance and make existing cancer treatments more effective. By elaborating on the value of diversity and inclusion in cancer research and treatment, the book also emphasizes the importance of all patients having equal access to innovative therapies. All things considered, this book is a great tool for researchers, doctors, and students in the cancer treatment sector.

  • Wellbeing and Ethics of Animals in Shelters

    • 1st Edition
    • Mandy Paterson + 1 more
    • English
    Wellbeing and Ethics of Animals in Shelters provides an up-to-date, all-in-one resource for animal care and shelter professionals seeking the latest guidance on improving sheltered animals’ quality of life. Central chapters review health and behavioral assessments for shelter animals, offer guidance for the care of shelter cats and dogs, and discuss key steps to the successful adoption of sheltered animals. Latter chapters explore the human component of shelter animal care. The book is an accessible and important resource for animal care and shelter professionals, animal welfare researchers, and students of animal behavior, biology, and veterinary sciences.Thousands of unwanted dogs, cats, and other animals are brought under the care of shelters around the world each year. The transition can be a frightening and stressful experience with physiological and behavioral implications for the animals. Written by renowned animal welfare experts, this book not only covers guidance on improving the lives of sheltered animals, but also explores how animals come to be under the care of shelters and the ethical considerations of sheltering animals.

  • The Pharmacology of Obesity

    • 1st Edition
    • Volume 107
    • English
    The Pharmacology of Obesity, Volume 107 in the Advances in Pharmacology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Obesity Therapeutic Landscape, Challenges, and Unmet Needs, Diagnosis and Evaluation of Obesity for Therapeutic Selection, When to use First-Generation Anti-Obesity Medications?, GLP-1 Receptor Agonists in our Clinics, Future Directions in Obesity Pharmacotherapy: Novel Targets and Pipeline Therapies, Destigmatizing Obesity: from language to the clinical environment, and much more.Additional chapters cover Role of Nutrition and physical Activity in the Therapy of Obesity, Behavioral and Lifestyle Strategies in Obesity Management and Post-Bariatric Follow-Up, The interpretation of Body-composition Metrics in Obesity, Digital Health, Technology, Artificial Intelligence, and Wearables in Obesity Care, Metabolic Aging and Obesity: how Physiology Changes with Age, Endoscopic Bariatric and Metabolic Therapies, and What Patients Could Benefit from Bariatric Surgery?

  • Introduction to Clinical Engineering

    • 2nd Edition
    • Samantha Jacques
    • English
    The Second Edition of Introduction to Clinical Engineering provides a comprehensive and systematically updated examination of the role of clinical engineering within modern healthcare systems. The text articulates how engineering principles are integrated into patient-centered care delivery, addressing a persistent gap created by the lack of formalized clinical engineering degree programs. It presents a practitioner-focused framework that supports safe and effective medical device use, workflow optimization, and compliance with regulatory requirements. This revised edition expands its scope to reflect the evolving healthcare technology landscape, introducing artificial intelligence at a conceptual level while offering deeper analysis of cybersecurity and healthcare information technology. Particular emphasis is placed on interoperability, hospital technology ecosystems, and the growing interdependencies among clinical systems. Updates to US regulatory policies and emerging cybersecurity risks are fully integrated throughout the text. Designed for healthcare practitioners and educators, Introduction to Clinical Engineering, Second Edition, delivers a coherent, analytically grounded approach to healthcare technology management. It supports evidence-based decision-making, technology lifecycle optimization, and regulatory compliance, while fostering workforce competency development and enabling the translation of theory into efficient, cost effective, and patient-centered clinical outcomes.

  • Pharmaceutical Hot Melt Extrusion

    From Materials Selection to Commercial Production
    • 1st Edition
    • Purnima D. Amin
    • English
    Pharmaceutical Hot Melt Extrusion: From Materials Selection to Commercial Production is an authoritative resource on the evolving landscape of HME technology. The book explores the core principles of formulation development, equipment design, process scaling, and regulatory considerations, providing essential knowledge for researchers and industry professionals. It emphasizes innovative, green manufacturing practices, solvent-free processes, and patient-centric delivery systems, making it a vital guide for advancing pharmaceutical and nutraceutical formulations. This reference enhances understanding of cutting-edge HME applications, supporting environmentally sustainable practices and innovative product development for both academia and industry.It equips formulation scientists, R&D professionals, and students with the knowledge to accelerate research, improve efficiency, and translate laboratory innovations into market-ready solutions.

  • Disorders of Memory

    • 1st Edition
    • Andrew E. Budson + 1 more
    • English
    Disorders of Memory provides a new update on research pertaining to memory disorders, with a central focus on differing components of memory processes, as well as clinical conditions affecting memory. The book covers methods of assessment and clinical treatment, management, and rehabilitation of these disorders. With chapters written by leading international experts, it provides an overview of our current knowledge on memory disorders that will be of benefit to both researchers and practitioners interested in neurology.

  • Plant-Induced Systemic Resistance

    Mechanisms and Applications Against Biotic and Abiotic Stressors
    • 1st Edition
    • Sengottayan Senthil-Nathan + 2 more
    • English
    Plant-Induced Systemic Resistance: Mechanisms and Applications Against Biotic and Abiotic Stressors examines how intrinsic defense signaling and state-of-the-art biotechnologies can fortify crops while reducing reliance on chemical inputs. This rigorous treatment unpacks the biochemical circuitry of induced immunity, the networks coordinating defense, and the innovative molecular biology tools that empower durable protection under a variety of stress triggers. Against the backdrop of rising pest pressures, evolving resistance patterns, and environmental concerns, it presents a forward-looking framework for integrating host defenses within comprehensive crop protection initiatives.This volume traces a clear trajectory from foundational concepts to precision management solutions, delivering data-driven methodologies, decision support tools, and scalable practices for sustainable agriculture, enriched by real-world case studies that illustrate adoption across research, extension, and industry contexts. Governance, regulatory considerations, and societal implications are woven throughout to ensure responsible innovation.Bridging lab-derived knowledge with field-ready interventions, this essential resource opens avenues for interdisciplinary collaboration to bolster plant resilience against various biotic and abiotic stressors, expanding the toolkit for integrated crop protection.

  • COVID-19 in New York City

    Public Health Crisis and its Aftermath
    • 1st Edition
    • Rainer W.G. Gruessner
    • English
    COVID-19 in New York City: A Five-Year Account presents a comprehensive account of the pandemic, from how events unfolded, how circumstances were handled, and how New Yorkers learned to better manage a similarly deadly pandemic in the future. The book documents the period from when the first case was diagnosed in New York City, addressing the medical, political, social, psychological, business, and environmental aspects, as well as the changes in behavior and lifestyle. The author shares his birds eye view of the city through a comprehensive investigation of the events, and the impact of the current and future implications for all readers.This book serves as a guide for anyone interested in how to handle and cope with a future deadly pandemic or similar disaster and is written by a physician and advocate for science who was living in New York City during the pandemic.

  • Probiotics

    A Comprehensive Exploration of Health Benefits and Innovation
    • 1st Edition
    • Ranbir Chander Sobti
    • English
    Probiotics: A Comprehensive Exploration of Health Benefits and Innovation explores the potential of probiotics and their fundamental role in human health and disease prevention. The book offers a thorough understanding of how beneficial microorganisms can enhance overall well-being and potentially transform treatment approaches across multiple disciplines. The first section lays the groundwork by exploring the fundamentals of probiotics, prebiotics, and their interactions with the human microbiome, while the second section examines the role of probiotics in disease prevention and management, highlighting their impact on conditions such as diabetes, obesity, and mental health.The third section discusses specialized applications of probiotics in women's health, pediatrics, and geriatrics, as well as their innovative uses in skin care and nutrition. Finally, the fourth section investigates the future potential of probiotics in synthetic biology, in personalized health, and in combatting antibiotic resistance. With contributions from a diverse group of experts in the field, the book serves as an interdisciplinary resource for researchers, clinicians, and industry professionals eager to explore the therapeutic potential and benefits of probiotics.

  • Comparative Fish Immunology

    • 1st Edition
    • Volume 42
    • English
    Comparative Fish Immunology, Volume 42 in the Fish Physiology series, presents chapters written by leading experts. Covering a broad range of topics, this edition explores the evolution and function of immune systems in fish, with particular attention to both innate and adaptive immune mechanisms across diverse aquatic species. Chapters examine adaptive immunity in jawless vertebrates and the unique VLR system, the role of antimicrobial peptides in teleost infections, and the use of zebrafish as a model for studying innate immune responses. Additional contributions explore pharyngeal mucosal lymphoid structures, the evolutionary origins of germinal centers in fish, and mechanisms of antigen presentation in teleosts.Other chapters address microbiota–host immune interactions, emerging insights into teleost neuroimmunology, and the modulation of immune function through behavioral fever. Together, these contributions provide a comprehensive overview of current discoveries and evolving perspectives in fish immunology, offering valuable insights for researchers, immunologists, and aquatic biologists interested in the physiology and immune biology of fishes.

  • Guide to Plant Transcription Factors

    • 1st Edition
    • Aryadeep Roychoudhury
    • English
    Guide to Plant Transcription Factors is the first comprehensive resource on the dynamics of transcription factor function in plants, covering their roles in process regulation, stress management, post-translational modification, and epigenetic control. The book explores how transcription factors can be manipulated or engineered for crop improvement, offering insights into their regulatory mechanisms and practical applications.Transcr... factors bind to upstream regions of target genes and recruit additional proteins, often facilitating chromatin remodeling to enable further binding. They play critical roles in diverse physiological processes, including seedling development, shoot and root growth, flowering, fruit ripening, seed maturation, nitrogen fixation, and photosynthesis. Plant transcription factors belong to numerous families, each with distinct mechanisms and functions. They also govern plant responses to pathogens and tolerance to abiotic stresses through complex gene regulatory networks.This volume provides a systematic overview of recent advances in transcription factor research, their relationship with stress tolerance, and the roles of individual transcription factors in plant systems. Featuring contributions from leading scientists worldwide, Guide to Plant Transcription Factors is an essential reference for researchers, academics, and advanced students in plant biology and biotechnology.

  • Respiratory Critical Illness During Pregnancy

    Critical Care in Obstetrics
    • 1st Edition
    • English
    Respiratory Critical Illness During Pregnancy: Critical Care in Obstetrics, a volume in the Critical Care Obstetrics series, provides a novel reference for healthcare personnel caring for pregnant women with various health compromises specific to respiratory complications. The book's chapters reflect the growing scope of critical care obstetrics and the increasing importance and recognition of the hospital structure's field, covering the most common respiratory complications that any patient can present during pregnancy, including Asthma, Pulmonary Hypertension and Infection, Cystic Fibrosis, Sleep Disorders, Respiratory failure and more.All intensivists, regardless of primary discipline, must possess a core set of critical care skills that allow them to manage critically ill patients. Here, the authors have gathered the best evidence-based material on respiratory scenarios.

  • Intelligence-Based Healthcare

    Artificial Intelligence Concepts with Real‑World Applications for Healthcare Leaders and Providers
    • 1st Edition
    • Anthony Chang + 2 more
    • English
    Intelligence-Based Healthcare: An Essential Guide with Case Studies of Artificial Intelligence for the Healthcare Leader and Provider is an essential guide with an introduction to data science and artificial intelligence to provide the reader with a quick orientation and education on AI in healthcare. This book also offers a framework for success in planning, deployment, implementation, and evaluation of AI models in healthcare. In 25 chapters, Intelligence-Based Healthcare: An Essential Guide with Case Studies of Artificial Intelligence for the Healthcare Leader and Provider both introduces the reader to artificial in medicine and healthcare, and AI concepts. To render AI more understandable and relatable to the reader, case studies are used as a learning strategy to illustrate the aforementioned AI concepts. The cases implement AI in solving a very specific problem, clinical or operational, in clinical medicine or healthcare. Both cases that illustrate successful implementation of AI as unsuccessful application cases with important lessons learned are included. Each chapter can be read independently and therefore the book is a valuable resource for researchers, health professionals, postgraduate students, post doc researchers and faculty members in the fields of artificial intelligence in medicine and healthcare, and all those who wish to broaden their knowledge in the allied field.

  • Protein Kinase Inhibitors

    The Promise of Natural Products in Cancer Therapeutics
    • 1st Edition
    • Md. Imtaiyaz Hassan + 1 more
    • English
    Protein Kinase Inhibitors: The Promise of Natural Products in Cancer Therapeutics explores a novel therapeutic avenue for cancer treatment through nutraceutical-based kinase inhibitors. The book covers their historical background, outlook, mechanistic pathways, and clinical aspects, highlighting their relevance in cancer therapy. It also examines the potential of polyphenolic derivatives and other natural compounds in inhibiting key kinases involved in major cancer signaling pathways, focusing on their application in clinical trials and marketed drugs. Sections explore the implications of polyphenols in cancer management, novel sources of breast cancer inhibitors, the role of natural products in lymphoma therapy, and the multitarget potential of phytochemicals. Each chapter is designed to provide a thorough understanding of how natural products can be harnessed to develop innovative cancer therapeutics. It will serve as a valuable resource for academics, scientists, young researchers, students, and pharmacists working or interested in kinase biology and cancer therapeutics with its unique perspective on using nature's own arsenal to combat cancer.

  • Chia Seeds

    Applications in the Agri-food Industry
    • 1st Edition
    • Shivani Pathania + 2 more
    • English
    Chia Seeds: Applications in the Agri-food Industry is a comprehensive guide to the properties of chia biomass (seeds, leaves, and ingredients/products thereof) and their utilization in the agri-food industry and beyond. The book is based on the analysis of chia value chain and summarizes the scientific, technical, and health aspects of chia (Salvia hispanica L.). Divided into 3 sections, it fills a critical gap in the literature by providing a comprehensive overview of chia biomass available to address key global bioeconomy and United Nation Sustainable Development Goals (SDGs) challenges.User will find advanced information for the utilization of chia-based biomass based on their specific properties, application of eco-efficient technologies for their processing and conversion into a variety of products for different groups of consumers, including those with special needs (e.g. celiac patients, vegans and vegetarians). In addition, the book offers practical guidance on the development of new value chains and their integration within the existing agri-food systems.

  • Technological Applications of Fungal Enzymes in Biorefinery and Bioproducts Development

    Volume 2
    • 1st Edition
    • Manikant Tripathi + 1 more
    • English
    Technological Applications of Fungal Enzymes in Biorefinery and Bioproducts Development provides a thorough understanding of technological advances and utilization of fungal enzymes for the development of useful products through using advanced microbial biotechnological techniques. This is the second of two volumes that provide a comprehensive overview of the utilization of fungal enzymes for biorefinery and bioproduct development. Volume 2 discusses basic and technological interventions in fungal enzyme applications exploring biotechnological strategies and how they can address challenges and solutions in the processes involved in fungal enzyme applications. The book also offers practical examples and case studies of technology advances in fungal enzyme-mediated development of biofuels and bioproducts. In combination with Volume 1, this book offers a holistic view of the potential and challenges of engineered fungal enzymes for researchers, scientists, and industry professionals seeking to deepen their knowledge of fungal enzymes and their role in biochemical advances.

  • Enzyme Technology for Environmental Sustainability, Waste to Wealth, and Circular Economy

    • 1st Edition
    • Shrikaant Kulkarni
    • English
    Enzyme Technology for Environmental Sustainability, Waste to Wealth, and Circular Economy offers a comprehensive look at how enzyme technology can drive environmental progress within the framework of biochemistry. Beginning with foundational concepts, the book introduces readers to the science behind enzymes and their practical applications. Each chapter builds upon these basics, illustrating how enzymes catalyze vital processes that contribute to sustainability and the transformation of waste into valuable resources. Through focused case studies and clear explanations, the book demonstrates the potential of enzyme-driven solutions to address urgent environmental challenges and promote a circular economy.Beyond its central focus, the book stands out by delivering pragmatic examples that remain within biochemical boundaries, avoiding broader discussions in public health or environmental science. It is designed as a valuable reference for biochemists, researchers, and industry professionals, emphasizing collaboration and innovation rooted in biochemical expertise. Readers will gain an enriched understanding of enzyme technology’s role in sustainable industrial practices and the future of environmentally responsible solutions.

  • Lifestyle Epigenomics

    • 1st Edition
    • Ana B Crujeiras
    • English
    Lifestyle Epigenomics, a new volume in the Translational Epigenetics series, comprehensively details the interplay between lifestyle factors and epigenetic modifications associated with the onset of noncommunicable diseases and aging, shedding light on potential preventive and therapeutic strategies for disease from an epigenomics perspective. Here, more than 35 international experts in the field consider how lifestyle choices or habits can condition or prevent disease, along with tools for new research, from bioinformatics methodology to non-invasive sampling.Early, foundational chapters are followed by all-inclusive sections on epigenetic machinery in health and disease; dietary factors and epigenetics; adiposity and physical activity and epigenetics; psychological stress, social environment, toxins and contaminants exposure effects on epigenetics; and transgenerational and childhood epigenetics. To support understanding, each chapter includes a summary and key points lists, terms and definition, as well as research case studies outlining core components of recent studies, detailing their conditions, research techniques involved, and outcomes.

  • Carrier-Free Enzyme Immobilization

    Fundamentals and Innovations in Biocatalysis
    • 1st Edition
    • Mehdi Mohammadi + 1 more
    • English
    Carrier-Free Enzyme Immobilization: Fundamentals and Innovations in Biocatalysis explores innovative techniques for immobilizing enzymes without the use of inert carriers, highlighting their advantages, applications, and integration into modern biocatalytic processes. The book begins by introducing the concept of enzyme immobilization and the transition from traditional carrier-bound methods to innovative carrier-free techniques. It discusses the fundamental principles behind carrier-free immobilization, including the types of cross-linkers used and the advantages in enhancing enzyme stability and activity. The book also covers various methods for the structural characterization of carrier-free immobilized enzymes.With a strong focus on practical implementation, it examines the applications of carrier-free immobilized enzymes across different industries, highlighting the pros and cons of the method. It explores novel approaches for producing carrier-free immobilized biocatalysts and provides a comparative analysis of carrier-free versus traditional carrier-bound immobilization techniques. The book also addresses the challenges associated with implementing carrier-free immobilization in industrial processes and proposes potential solutions to overcome these obstacles. It is an essential resource for biochemists, chemical engineers, and researchers in biotechnology who are involved in enzyme research and development.

  • Building Blocks of Neuroimmunometabolism

    From Molecular Pathways to Therapeutic Strategies
    • 1st Edition
    • Sachchida Nand Rai + 2 more
    • English
    Building Blocks of Neuroimmunometabolis... From Molecular Pathways to Therapeutic Strategies offers an authoritative exploration of the intricate relationship between the immune system and neurodegenerative diseases. This essential resource addresses the critical gap in understanding how immune responses and metabolic processes jointly influence the onset and progression of conditions such as Alzheimer’s, Parkinson’s, and multiple sclerosis. The book provides an examination of key molecular pathways and cellular interactions, emphasizing the role of immunometabolism in disease mechanisms. Beginning with an introduction to the concept of immunometabolism, it explores the connections between the immune and nervous systems, setting the stage for understanding neurodegenerative diseases.In addition, the book discusses pivotal topics such as the role of microglia and macrophages in neuroinflammation, the metabolic regulation of T cells, and the impact of oxidative stress and mitochondrial dysfunction. The gut-brain axis is examined for its influence on brain health, alongside innovative therapeutic strategies targeting immunometabolic pathways and lifestyle interventions.

  • Moving Toward Nonanimal Approaches in Medical Research and Testing

    • 1st Edition
    • Gail A. Van Norman + 1 more
    • English
    Moving Toward Nonanimal Approaches in Medical Research and Testing pioneers a single-source guide for researchers regarding nonanimal research tools and methodologies and their many advantages and applications in place of animals. This book is presented in three parts: historical, ethical, legislative, and scientific contexts on the need to shift away from animal-based research and testing; the latest advances in nonanimal tools and methods for biomedical research and testing of human therapeutics and other compounds, including microphysiological systems, bioprinting, biobanks, and artificial intelligence; and achieving a practical shift toward these powerful approaches, including advocacy for legal, regulatory, and policy change, securing funding for nonanimal studies, and how to overcome bias against nonanimal methods. This book, primarily directed to researchers in biomedicine, human medical therapeutics, and toxicology, will also appeal to researchers in industry, providing overview and insights about the latest applications of nonanimal research tools and methods for product development and testing. Clinicians who wish to understand the reliability of testing therapeutics with nonanimal versus animal methods, as well as advocacy groups seeking an up-to-date understanding of ethical, economic, political, and scientific considerations in moving toward nonanimal approaches, will also find significant value in this text. Finally, legislators and those involved in regulatory review and oversight will benefit from this single comprehensive source for developing a basic understanding of nonanimal research and human safety.

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