Mucosal Barriers and Host-Microbiota Interplay
Dysbiosis to Barrier Dysfunction
- 1st Edition - June 1, 2026
- Latest edition
- Editor: Linda Chia-Hui Yu
- Language: English
Mucosal Barriers and Host-Microbiota Interplay: Dysbiosis to Barrier Dysfunction, a volume in Elsevier's new series Hot Topics in Physiology, provides an in-depth exploration o… Read more
Mucosal Barriers and Host-Microbiota Interplay: Dysbiosis to Barrier Dysfunction, a volume in Elsevier's new series Hot Topics in Physiology, provides an in-depth exploration of mucosal barriers, including their structure, establishment, and consideration of different diseases and intervention strategies. Published in association with the International Union of Physiological Sciences (IUSP), this is an ideal reference for those researching or studying biology and medicine, particularly gastroenterology. Biotechnological companies working on metagenomics sequencing and analysis may also find this volume useful.
As a massive load of commensal microbes, consisting of bacteria, viruses, and fungi resides in the gastrointestinal tract and other mucosal surfaces, collectively termed microbiota, this book provides an update on new and existing knowledge. Mucosal barriers, including the epithelial layers and immune cells act as the frontline to strategically confine these microorganisms and prevent the entry of microbes into the body proper.
As a massive load of commensal microbes, consisting of bacteria, viruses, and fungi resides in the gastrointestinal tract and other mucosal surfaces, collectively termed microbiota, this book provides an update on new and existing knowledge. Mucosal barriers, including the epithelial layers and immune cells act as the frontline to strategically confine these microorganisms and prevent the entry of microbes into the body proper.
- Presents the pathophysiology of host-microbiota crosstalks
- Explores the unconventional roles of epithelial barrier structures involved in intestinal homeostasis
- Teaches how microbiota dysbiosis and barrier dysfunction contribute to disease pathogenesis
Biologists, Physicians, and Gastroenterologists
1. Host Barriers against Microbiota: Traditional Views and Recent Advances
2. Neonatal Establishment of Microbiome Ecosystem and Intestinal Barrier: How Developmental Programming of Gut Microbiota Impacts Adult Disease Progression
3. Epithelial Junctional Proteins for Physical Defense, Cell-Cell Contact, and Polarity Complex
4. Unconventional Roles of Tight Junctions in Cell Survival and Ion Transport
5. Epithelial Microvilli and Transcellular Permeability in the Cause-and-Effect Relationship between Barrier Dysfunction and Microbiota Dysbiosis
6. Wound Healing and Barrier Integrity: Cellular and Molecular Players in Gastric Mucosal Repair
7. Mucosal Pathophysiology: The Role of Gut Microbiota Biofilms during Host-Pathogen Interplay
8. Antagonism between Gut Microbiota Modulates the Progression of Chronic Hepatitis
9. The Role of Microbiome-Mucosal Barrier Interactions in Neoplastic Diseases
10. The Interplay of Gut Microbiota and Energy Homeostasis in Obesity-related Diseases
11. Refining the Role of Gut Microbiota in the Developmental Programming of Cardiovascular Kidney Metabolic Syndrome
12. Interrelationship between Intestinal Immune Cells and Barrier Function in the Development of Neurodegenerative Diseases
13. Intestinal Epithelial Cells: Gatekeepers of Gut-Brain Axis, Microbiome, and Beyond
14. Epithelial Barriers and Microbiota-Gut-Brain Axis, Microbiome, and Beyond
15. The Role of Gut Microbiota in Cancer Development and Translational Modulation Strategies
16. Diagnostic and Therapeutic Potentials Targeting the Interplay of Host Barriers and Microbiota in Human Diseases
17. The Dietary Restoration of Intestinal Barrier Function by Nutrient-Sensing Receptors
18. Dietary Factors and Next-Generation Probiotics for Microbiota Eubiosis and Barrier Fortification
2. Neonatal Establishment of Microbiome Ecosystem and Intestinal Barrier: How Developmental Programming of Gut Microbiota Impacts Adult Disease Progression
3. Epithelial Junctional Proteins for Physical Defense, Cell-Cell Contact, and Polarity Complex
4. Unconventional Roles of Tight Junctions in Cell Survival and Ion Transport
5. Epithelial Microvilli and Transcellular Permeability in the Cause-and-Effect Relationship between Barrier Dysfunction and Microbiota Dysbiosis
6. Wound Healing and Barrier Integrity: Cellular and Molecular Players in Gastric Mucosal Repair
7. Mucosal Pathophysiology: The Role of Gut Microbiota Biofilms during Host-Pathogen Interplay
8. Antagonism between Gut Microbiota Modulates the Progression of Chronic Hepatitis
9. The Role of Microbiome-Mucosal Barrier Interactions in Neoplastic Diseases
10. The Interplay of Gut Microbiota and Energy Homeostasis in Obesity-related Diseases
11. Refining the Role of Gut Microbiota in the Developmental Programming of Cardiovascular Kidney Metabolic Syndrome
12. Interrelationship between Intestinal Immune Cells and Barrier Function in the Development of Neurodegenerative Diseases
13. Intestinal Epithelial Cells: Gatekeepers of Gut-Brain Axis, Microbiome, and Beyond
14. Epithelial Barriers and Microbiota-Gut-Brain Axis, Microbiome, and Beyond
15. The Role of Gut Microbiota in Cancer Development and Translational Modulation Strategies
16. Diagnostic and Therapeutic Potentials Targeting the Interplay of Host Barriers and Microbiota in Human Diseases
17. The Dietary Restoration of Intestinal Barrier Function by Nutrient-Sensing Receptors
18. Dietary Factors and Next-Generation Probiotics for Microbiota Eubiosis and Barrier Fortification
- Edition: 1
- Latest edition
- Published: June 1, 2026
- Language: English
LY
Linda Chia-Hui Yu
Dr. Yu reeived her PhD in 2002 from McMaster University in Ontario, Canada. She joined the National Taiwa University College of Medicine, Taipei, Taiwan in 2005, becoming full Professor in 2016. Her lab investigates pathophysiological mechanisms of intestinal epithelial biology and mucosal immuno-oncology. The research interest is focused on host-microbe interaction for regulation of epithelial barrier function and tumorigenesis in the gastrointestinal tract. She's received many honors and awards, and is currently a member of the Chinese Physiology Society (CPS), the American Physiology Society (APS) and the American Gastroenterology Association (AGA). Additionally, Dr. Yu is a Council Member of the International Union of Physiological Sciences (IUPS.
Affiliations and expertise
Professor, Graduate Institute of Physiology, National Taiwan University College of Medicine, Taipei, Taiwan