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Hormones in Neuroscience

The Pancreas and Pancreatic Hormones

  • 1st Edition - July 13, 2026
  • Latest edition
  • Editors: Victor R. Preedy, Colin R. Martin, Rajkumar Rajendram, Vinood B. Patel
  • Language: English

Hormones in Neuroscience: The Pancreas and Pancreatic Hormones explores the latest research in neuroendocrinology in relation to the pancreas and pancreatic hormones. This volume… Read more

Description

Hormones in Neuroscience: The Pancreas and Pancreatic Hormones explores the latest research in neuroendocrinology in relation to the pancreas and pancreatic hormones. This volume aims to cover the deficiencies in existing literature on the link between hormones and neurological tissues. This book offers a translational context and seeks to address the behavioral consequences of altered endocrine gland pathology while also addressing causative and modulating influences.

Key features

  • Offers an overview of the pancreas and pancreatic hormones in relation to the human nervous system
  • Covers focused areas of neurological pathology and physiology, including dementia, neuropathy
  • Offers treatment regimens for insulin resistance and the neurological and behavioral effects, including the impact of diet and nutrition on aspects of behavior
  • Distills important information at the end of each chapter, including summary points and translational applications of the material

Readership

Neuroendocrinologists, neuroscientists, pathologists, research scientists, and molecular or cellular biochemists in the field of hormone neuroscience

Table of contents

Section 1. Introductory Chapters

1. Pancreatic hormones: a focus on amylin―a new narrative

2. Computational modeling of the pancreas and pancreatic function

3. Pancreatic hormones and the gut-brain axis

4. Somatostatin: a crossroad between pancreatic and neural pathways

5. Feeding and fasting and impact on pancreatic hormones: insulin and beyond

Section 2. Focused areas of neurological pathology and physiology

6. Type 2 diabetes and the increased risk of dementia

7. The interstitial fluid dynamics and diabetes mellitus

8. Brain insulin receptor gene networks, behavior and disease risk over the life course

9. Linking exosomes and neuropathy in diabetics conditions

10. The divalent metal transporter-1 (DMT1), neuroprotection and insulin

11. Peripheral nerves in diabetic neuropathy: Features and methods

12. Linking brain insulin receptors, neural stem cells and synaptic plasticity: potential implications for
neurodegenerative disorders

Section 3. Psychology and behavior as a consequence of changes in the pancreas or pancreatic endocrine status or the effects of hormones

13. Cognitive links with brain insulin signaling in metabolism: a new narrative

14. Insulin-linked synaptic modulation in Alzheimer’s pathology: Emerging potential of nanofibers

15. Sexual dysfunction and mood symptoms in diabetic

16. Anxiety related behavior in parents of diabetic children

17. Insulin signaling and impairments in executive functions in preclinical models: a narrative approach

Section 4. Treatment regimens modulating pancreatic hormones status and impact on neurological tissues and behavior

18. Drugs used in treating diabetes and insulin resistance: neurological and behavioral effects

19. Insulin treatments and effects on neurotransmitters

20. Pancreas and pancreatic hormones: insulin dosing behavior and “insulin metrics”

21. Metformin treatment and effects on psychiatric behaviors: Measures of depression

22. Psychotherapeutic interventions in diabetes care: a narrative review and conceptual framework of CBT and beyond

23. Modulation of oxidative stress in the management of pancreatitis

24. Diabetic complications with emphasis on neuropathy: Mechanistic insights and therapeutic role of aldose reductase inhibitors

25. Diabetes care and molecular pathways in treatment using phytomedicines

26. Hypothalamic neurons and treatment with metformin and propionate

Section 5. Non-pancreatic treatment regimens and effects on neuroscientific domains

27. Statins and insulin resistance

28. Linking mitochondrial integrity and insulin resistance in response to pharmacological agents

29. Insulin secretion and effects of beta-adrenergic blockers

30. Focused review: Clozapine safety and effects on pancreatitis

Section 6. Diseases of the pancreas or pancreas hormones status and impact on brain and behavior

31. Pancreatic cancer―An overview

32. Acute pancreatitis and its impact on mental health

Section 7. Diet and nutrition and impact on the pancreas and neuroscientific domains or behavior

33. Diet, diabetes and gene expression in the brain

34. Diet, behavior and diabetes―an overview

35. Brain insulin signaling and nutritional modulation: the role of microRNAs and the gut—brain axis

36. Vitamins, analog and effects on insulin signaling in the brain

37. Recommended resources for the study of hormones in neuroscience: The Pancreas and Pancreatic Hormones

Product details

  • Edition: 1
  • Latest edition
  • Published: July 13, 2026
  • Language: English

About the editors

Victor R. Preedy

Editor

Victor R. Preedy, BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC, FRSM, is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He also holds an Honorary Professorship at the University of Suffolk and served as the long‑term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy graduated with an Honours Degree in Biology and Physiology with Pharmacology and later obtained his PhD from the University of London. He subsequently received Membership of the Royal College of Pathologists and later earned his second doctorate (DSc) in recognition of his contributions to protein metabolism. He is a Fellow of the Royal Society of Medicine, the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health and Hygiene, the Royal Society for Public Health, and the Royal Society of Chemistry. Professor Preedy has conducted research while affiliated with Imperial College London, the School of Pharmacy (now part of University College London), and the MRC Centre at Northwick Park Hospital. He has collaborated widely with international research groups in Finland, Japan, Australia, the USA, and Germany. His longstanding academic interests include health and well‑being. He has published more than 750 works, including peer‑reviewed research articles, abstracts, symposium presentations, reviews, and edited books.

Affiliations and expertise
Professor, Department of Clinical Biochemistry, King’s College Hospital, London, UK; Emeritus Professor, Faculty of Life Sciences and Medicine, King’s College London, UK; Visiting Professor, University of Hull, UK

Colin R. Martin

Editor
Colin R. Martin RN, BSc, MSc, PhD, MBA, YCAP, FHEA, C.Psychol, AFBPsS, C.Sci is Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director of the Institute of Health and Wellbeing at the University of Suffolk, UK. He is a Chartered Health Psychologist and a Chartered Scientist. He also trained in analytical biochemistry, this aspect reflecting the psychobiological focus of much of his research within mental health. He has published or has in press well over 300 research papers and book chapters. He is a keen book author and editor having written and/or edited more than 50 books. These outputs include the prophetic insight into the treatment of neurological disease, Handbook of Behavior, Food and Nutrition (2011), Nanomedicine and the Nervous System (2012), Oxidative Stress and Dietary Antioxidants in Neurological Disease (2020), Zika Virus Impact, Diagnosis, Control and Models (2021), Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior and Diet (2021), Diagnosis and Treatment of Spinal Cord Injury (2022), The Neurobiology, Physiology, and Psychology of Pain (2022) and The Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging (2023). Professor Martin is particularly interested in all aspects of the relationship between underlying physiological substrates and behavior, particularly in how these relationships manifest in both acute and chronic psychiatric disorder. He has published original research germane to significant mental health disorders including the areas of schizophrenia, anxiety, depression, self-esteem, alcohol and drug dependency, high secure forensic mental health and personality disorder. He has a keen interest in the impact of postviral illness and is actively involved in clinical research post-Covid pandemic and in particular, the impact of Long Covid on psychological, neurological, physiological and social functioning. He is involved in collaborative International research with many European and Non-European countries.
Affiliations and expertise
Visiting Professor of Perinatal Wellbeing, Institute for Health and Wellbeing, University of Suffolk, Ipswich, UK

Rajkumar Rajendram

Editor

Dr Rajkumar Rajendram is a clinician-scientist with expertise in internal medicine, anaesthesia, intensive care and peri-operative medicine. He graduated with distinctions from Guy’s, King’s and St Thomas’ Medical School, King’s College London, in 2001, where he received several prizes, merits and distinctions in pre-clinical and clinical subjects.

Dr Rajendram completed specialist training in acute and general medicine in Oxford and subsequently held a Consultant appointment in Acute General Medicine at the John Radcliffe Hospital, Oxford. He also trained in anaesthesia and intensive care in London, including advanced training in regional anaesthesia and intensive care, and subsequently held a Consultant appointment in Intensive Care, Anaesthesia and Peri-operative Medicine at the Royal Free London Hospitals.

His postgraduate training has spanned internal medicine, anaesthesia, intensive care and point-of-care ultrasound (POCUS). He was awarded Fellowship of the Royal College of Anaesthetists in 2009, Fellowship of the Faculty of Intensive Care Medicine in 2013, and the European Diploma in Intensive Care Medicine in 2014. He is a Fellow of both the Royal College of Physicians of Edinburgh and the Royal College of Physicians of London.

Dr Rajendram is currently a Consultant at King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia, and holds a joint appointment as Associate Professor in the Research Unit, Department of Medical Education, at King Saud bin Abdulaziz University for Health Sciences.

His multidisciplinary clinical background has informed his research interests in nutrition, fluid management and fluid balance in health and disease, particularly in acutely and critically ill patients. His research has also addressed POCUS, COVID-19 phenotypes and nutritional support in illness. Dr Rajendram has contributed extensively to medical research and education and has authored more than 400 textbook chapters, review articles, peer-reviewed papers and conference abstracts.

Affiliations and expertise
Consultant, Medical Protocol Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia & Joint Appointment Associate Professor, Research Unit, Department of Medical Education, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia

Vinood B. Patel

Editor

Vinood B. Patel, BSc, PhD, FRSC, is Professor in Clinical Biochemistry at the University of Westminster. In 2014 Dr Patel was elected as a Fellow to The Royal Society of Chemistry. Dr Patel graduated from the University of Portsmouth with a degree in Pharmacology and completed his PhD in protein metabolism from King’s College London in 1997. His postdoctoral work was carried out at Wake Forest University Baptist Medical School, NC, USA studying structural-functional alterations to mitochondrial ribosomes, where he developed novel techniques to characterize their biophysical properties. Research is being undertaken to study the role of nutrients, antioxidants, phytochemicals, iron, alcohol and fatty acids in the pathophysiology of disease. Other areas of interest are identifying new biomarkers that can be used for the diagnosis and prognosis of disease and understanding mitochondrial oxidative stress. Dr Patel is a nationally and internationally recognized researcher and has several edited biomedical books related to health and well being These books include Ancient and traditional foods, plants and herbs and spices in human health; coffee in health and disease prevention, Nuts and seeds in health and disease prevention Handbook of Substance Misuse and Addictions: From Biology to Public Health, tea in health and disease prevention.

Affiliations and expertise
Professor, Clinical Biochemistry, School of Life Sciences University of Westminster, London, UK

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