Advances in Diffusion Magnetic Resonance Imaging for Neurodegenerative Diseases Research

Advances in Diffusion Magnetic Resonance Imaging for Neurodegenerative Diseases Research provides a summary and discussion of the contribution of diffusion MRI to our understanding of the most common neurodegenerative diseases and bridges common microstructural changes across symptoms and disorders to unravel possible shared mechanisms of neurodegeneration.

The book opens by covering the technical basis of diffusion MRI with a focus on the interpretation of its imaging-derived metrics in terms of neuronal damage. Subsequent chapters are organized by disease and take an in depth look at how the use of diffusion MRI has contributed to recent understanding and how it has motivated potential new therapeutic structures for Alzheimer’s disease, frontotemporal dementia, primary aggressive aphasia, Parkinson’s disease, progressive supranuclear palsy, Huntington’s disease, motor neuron diseases, multiple sclerosis, as well as fragile-X syndrome and other genetic disorders. The book concludes with implications for future research, providing a must-have reference for researchers as well as clinicians in the field of neuroimaging of neurodegenerative disorders.