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Advances in Diffusion Magnetic Resonance Imaging for Neurodegenerative Diseases Research

  • 1st Edition - June 24, 2026
  • Latest edition
  • Editor: Frederic Sampedro
  • Language: English

Advances in Diffusion Magnetic Resonance Imaging for Neurodegenerative Diseases Research covers how diffusion MRI has contributed to our understanding of a wide range of neurodege… Read more

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Description

Advances in Diffusion Magnetic Resonance Imaging for Neurodegenerative Diseases Research covers how diffusion MRI has contributed to our understanding of a wide range of neurodegenerative diseases, unraveling early microstructural brain damage even at presymptomatic stages. Sections cover the technical basis of diffusion MRI, focusing on the interpretation of its imaging-derived metrics in terms of neuronal damage. Subsequent chapters are organized by disease, taking an in-depth look at how the use of diffusion MRI has contributed to our recent understanding of, and motivated potential new monitoring and therapeutic strategies for Alzheimer's disease, frontotemporal dementia, Parkinson's disease, multiple sclerosis, progressive supranuclear palsy, Huntington's disease, multiple system atrophy, motor neuron diseases, and more.

The book concludes with implications for future research, making it a must-have reference for researchers and clinicians interested in the field of neuroimaging for neurodegenerative disorders.

Key features

  • Discusses the benefits of diffusion MRI as a widely available, non-invasive, and cost-effective neuroimaging technique
  • Covers how diffusion MRI-derived metrics can assist in identifying early neuronal damage in a host of neurodegenerative diseases
  • Reviews the potential of diffusion MRI-derived metrics as novel imaging biomarkers for specific neurological disorders​​, with potential use in clinical trials

Readership

Researchers and clinicians in the field of neuroimaging of neurodegenerative disorders, General medicine

Table of contents

  1. ⁠Introduction to diffusion MRI in neurodegenerative disorders
  2. ⁠Advances in diffusion MRI in Alzheimer’s disease
  3. ⁠Advances in diffusion MRI in frontotemporal dementia
  4. ⁠Advances in diffusion MRI in Parkinson’s disease
  5. ⁠Advances in diffusion MRI in Huntington’s disease
  6. ⁠Advances in diffusion MRI in progressive supranuclear palsy
  7. ⁠Advances in diffusion MRI in multiple system atrophy
  8. ⁠Advances in diffusion MRI in neurodegenerative cerebellar ataxias
  9. ⁠Advances in diffusion MRI in motor neuron diseases
  10. ⁠Advances in diffusion MRI in multiple sclerosis
  11. ⁠Concluding remarks and implications for future research

Product details

  • Edition: 1
  • Latest edition
  • Published: June 25, 2026
  • Language: English

About the editor

FS

Frederic Sampedro

​​Frederic Sampedro, MD, PhD, BEng, MBA. Medical Doctor (MD), Computer Scientist BSc (Honors), Biomedical Engineer MSc, Electrical Engineer MSc, Artificial Intelligence MSc and MBA in Tech-based business administration, has a PhD in medical image analysis (extraordinary doctorate award) and over 15 years research experience in medical imaging, with a focus on computational neuroimaging of neurodegenerative disorders. He has over 80 indexed journal papers (~40 as first or corresponding author), total IF >400, h-index>22, >1200 citations and is director of several PhD theses and reviewer for multiple top journals in this field. He is a visiting lecturer at several universities and research institutes in Spain. Frederic Sampedro is a member of the Editorial Board of the Journal of Neuroradiology, official publication of the French Society of Neuroradiology (SFNR).​
Affiliations and expertise
University Hospital of Sant Pau, Radiology Department, Barcelona, Spain

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