Skip to main content
Elsevier

Books in Life sciences

  • Advances in Sugarcane Research: From Molecular Insights to Field Applications

    • 1st Edition
    • Volume 119
    • English
    Advances in Sugarcane Research: From Molecular Insights to Field Applications presents a comprehensive and integrative overview of contemporary sugarcane science, bridging fundamental discoveries with crop modeling and climate change. As one of the world’s most important crops for sugar and bioenergy production.This volume brings together leading experts to explore advances across multiple scales of research—from genomics, molecular biology, and genetic improvement to plant physiology, stress responses, and crop management. Emerging approaches such as omics technologies, artificial intelligence, and functional genomics are addressed as a way to transform sugarcane breeding and accelerating the development of climate-resilient cultivars. In addition to molecular and physiological perspectives, the book addresses key aspects of agronomy, including plant nutrition, soil constraints, root system dynamics, and sustainable management practices. Special attention is given to abiotic stresses such as drought and ozone, as well as their underlying mechanisms and implications for sugarcane growth. The integration of crop modeling and agrometeorology further provides tools for predicting crop performance and supporting decision-making under limiting environmental conditions. Overall, this volume aims to serve as a key reference for understanding current progress and future directions in sugarcane research.

  • Comparative Fish Immunology

    • 1st Edition
    • Volume 42
    • English
    Comparative Fish Immunology, Volume 42 in the Fish Physiology series, presents chapters written by leading experts. Covering a broad range of topics, this edition explores the evolution and function of immune systems in fish, with particular attention to both innate and adaptive immune mechanisms across diverse aquatic species. Chapters examine adaptive immunity in jawless vertebrates and the unique VLR system, the role of antimicrobial peptides in teleost infections, and the use of zebrafish as a model for studying innate immune responses. Additional contributions explore pharyngeal mucosal lymphoid structures, the evolutionary origins of germinal centers in fish, and mechanisms of antigen presentation in teleosts.Other chapters address microbiota–host immune interactions, emerging insights into teleost neuroimmunology, and the modulation of immune function through behavioral fever. Together, these contributions provide a comprehensive overview of current discoveries and evolving perspectives in fish immunology, offering valuable insights for researchers, immunologists, and aquatic biologists interested in the physiology and immune biology of fishes.

  • Thiamine and Thiamine-Pyrophosphate (TPP) Riboswitches

    • 1st Edition
    • Volume 735
    • English
    This volume of "Methods in Enzymology" series is devoted to the cofactor thiamine, also known as vitamin B1, and its phosphorylated derivatives. The biosynthesis of thiamine is discussed in terms of key enzymes and their regulation, the evolution of metabolic pathways, and its importance in plant and yeast metabolism. The importance of quantifying and distinguishing between phosphorylated and unphosphorylated thiamine in animal and human tissues using chromatographic, enzymatic, and nanopore methods is also discussed. In addition to these methods, thiamine riboswitches are a major focus of this book, covering everything from their identification in plants and the elucidation of their structure to their application in detection.This book presents state-of-the-art methods and detailed protocols intended for all researchers interested in thiamine metabolism or its detection.

  • Cell Death Part E

    • 1st Edition
    • Volume 210
    • English
    Cell Death: Part E, Volume 210 presents the latest advances and comprehensive reviews in the rapidly evolving field of cell death. This volume explores the molecular mechanisms, regulatory pathways, and biological consequences of various forms of cell death—including apoptosis, necrosis, autophagy, and other non-canonical processes. Chapters in this new release include Flow cytometry analysis of mitochondrial apoptotic priming with BH3 profiling on senescent cells, Methods to study PIDDOsome and caspase 2 signaling, Isolation, characterization, and experimental applications of apoptotic bodies in vitro, Lipid ROS Measurement by Spectral Flow Cytometry based on the ratiometric dye BODIPYTM C11 581/591, and much more.Additional chapters cover CRISPR-Cas9 Screen to Identify Genes Regulating Cell Death, Flow cytometry-assisted discrimination of early apoptotic, late apoptotic and primary necrotic morphological markers in Saccharomyces cerevisiae, Cytofluorometric analysis of cell death in primary human neutrophils, Real-time tracking of cell death in human intestinal organoids: a quantitative imaging approach, and more.

  • Advanced and Integrative Therapeutic Strategies in Parkinson’s Disease Management

    • 1st Edition
    • Wael Mohamed
    • English
    Advanced and Integrative Therapeutic Strategies in Parkinson’s Disease Management offers a comprehensive exploration of the latest innovations and multidisciplinary approaches in Parkinson’s Disease treatment. The volume is organized into sections covering genetic therapies, gut microbiota, artificial intelligence, virtual reality, neuroprotective strategies, polypharmacy, and combination therapies. It addresses the integration of personalized medicine, neuroprotective diets, natural products, cognitive enhancers, and ethical considerations. Additional chapters introduce traditional medicine, music therapy, and the synergy between pharmacotherapy and complementary modalities. The book equips readers with the knowledge to implement innovative therapies, navigate complex ethical landscapes, and integrate multidisciplinary and complementary approaches.This reference is essential for those seeking to advance clinical practice and research in Parkinson’s Disease through the adoption of cutting-edge strategies.

  • Advances in Virus Research

    • 1st Edition
    • Volume 125
    • English
    Advances in Virus Research, Volume 125 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters surrounding online resource hubs for modeling viruses/databases to support virology communities

  • Alternative Proteins

    • 1st Edition
    • Volume 154
    • English
    Alternative Proteins, Volume 154 provides a comprehensive overview of alternative proteins, exploring their sources, production technologies, nutritional profiles, and potential to transform the global food system. Covering plant-based, microbial, insect, and cultured (cell-based) proteins, the book examines the scientific advances, market trends, regulatory challenges, and sustainability implications of these innovative protein sources. Chapters in this new release include Introduction to Alternative Proteins, Molecular Properties of Plant-Based Proteins for Alternative Proteins, The Science of Alternative Proteins: Comparing Animal and Plant-Based Sources, Blue Proteins: Marine-Derived Alternatives for Sustainable Nutrition and Climate-Resilient Food Systems, and much more. Additional sections cover Insect Proteins for Alternative Proteins: Sustainable Solutions with Molecular Efficiency, Plant-Based Proteins: Key Sources and Production Methods, Fungal proteins as Eco-friendly Alternate Proteins, Algae and Microbial Proteins for Alternative Proteins: Untapped Molecular Resources, Integrating Siddha Dietary Principles with Alternative Protein Systems: A Pathway Toward Sustainable and Functional Nutrition, Alternative Proteins: Structure and Functional Properties, and a variety of extensive and timely topics.

  • Evolutionary Adaptations and Mosquito-Borne Viruses

    • 1st Edition
    • Volume 70
    • English
    Evolutionary Adaptations and Mosquito-Borne Viruses comprises comprehensive reviews of various topics in mosquito adaptations and mosquito-virus interactions, with insights into future research prospects. The topics covered in this volume include mechanisms of insecticide resistance, thermal and desiccation tolerance, insect-specific viruses and their interactions with pathogenic viruses, mosquito viral immunity, factors affecting vector competence, host preference, saliva and viral pathogenesis, microbiota and symbionts, gene drives and genetic modification of mosquitoes, and microRNA roles in mosquito-virus interactions.

  • The Inflammatory Ecosystem and Inflammazones

    Mapping the Complex Terrain of Inflammatory Diseases
    • 1st Edition
    • Erwei Song + 1 more
    • English
    The Inflammatory Ecosystem and Inflammazones: Mapping the Complex Terrain of Inflammatory Diseases offers a groundbreaking framework for understanding inflammation across multiple spatial and molecular levels. The book introduces the concept of distinct inflammazones—local, regional, distal, and systemic—and explores how their interactions influence disease development, progression, and resolution. This holistic approach integrates cellular, molecular, microbiome, and systemic responses, addressing a critical gap in current knowledge and advancing diagnostics and therapies for diseases like autoimmunity and cancer. The book is organized into six sections, starting with foundational principles and progressing through mechanisms of local, regional, and systemic inflammazones.It covers key components such as cytokines, chemokines, immune cells, and the roles of non-immune cells like fibroblasts and epithelial cells. The final sections focus on systems-level insights, including inflammaging, metabolism, and multi-omics technologies, culminating in strategies for personalized medicine and clinical translation. Each chapter combines cutting-edge research with clinical relevance, making complex concepts accessible and actionable.

  • Metabolomic Phenotyping for the Future of Personalized Medicine

    Beyond the Biomarkers
    • 1st Edition
    • Jacopo Troisi + 1 more
    • English
    Metabolomic Phenotyping for the Future of Personalized Medicine: Beyond the Biomarkers takes a critical look at the advancements in the field. It begins by explaining the essential steps of metabolomics analysis—from sample collection to data interpretation—while exploring how these workflows pave the way for targeted medical applications. With a focus on precision, it shows how metabolomics provides key insights into the mechanisms behind diverse phenotypes, making it an indispensable asset for biomedical research. The second section dives into the transformative results achieved in major medical domains through metabolomics, detailing how this emerging science contributes to understanding complex disease mechanisms.The book also outlines the international regulatory framework essential for conducting research within this field, ensuring compliance and ethical standards. By combining practical guidelines with visionary insights, this text serves as a cornerstone for future strides in personalized medicine and highlights the growing influence of metabolomics in shaping tomorrow’s healthcare systems.

  • An Illustrated Guide to Cancer Biology

    • 1st Edition
    • Tomas Koltai + 1 more
    • English
    An Illustrated Guide to Cancer Biology offers a comprehensive exploration of the fundamentals of oncological molecular biology and provides valuable insights into topics such as cancer cell migration, chemotherapeutic drug mechanisms, and the roles of RNA in cancer. With 33 chapters covering a wide array of subjects, including the Hanahan and Weinberg hallmarks of cancer, tumor heterogeneity, and hormone-dependent cancer, this guide serves as an indispensable resource for researchers, students, and practicing oncologists in medicine, oncology, and biochemistry alike. This book stands out not only for its comprehensive coverage of diverse topics but also for its unique approach.With over 400 figures strategically interspersed throughout the text, this book offers readers a visually engaging journey through the intricacies of cancer biology. These illustrations, ranging from molecular pathways to cellular interactions, make navigating topics like chemotherapeutic drug mechanisms and tumor heterogeneity more accessible. Additionally, the inclusion of sections on repurposing drugs, tumor kinetics, and epigenetics further aids in a deep understanding of cancer biology.

  • Surgical and Non-Surgical Advances in Stroke Management and Therapeutics

    • 1st Edition
    • Creed M. Stary + 2 more
    • English
    Surgical and Non-Surgical Advances in Stroke Management and Therapeutics offers a comprehensive exploration of contemporary stroke care. This essential resource synthesizes the latest research and clinical innovations, providing in-depth insights into advanced surgical techniques, emerging therapies, and interdisciplinary approaches to stroke treatment. Readers will gain a thorough understanding of both acute and chronic stroke management, enriched by expert commentary from leading clinicians and researchers. Covering everything from pioneering non-invasive interventions to state-of-the-art surgical strategies, this book delivers a critical framework for healthcare professionals dedicated to optimizing patient outcomes and rehabilitation.

  • Geriatric Neurosurgery in Clinical Practice

    • 1st Edition
    • Joe M. Das
    • English
    Geriatric Neurosurgery in Clinical Practice is an essential resource that provides a thorough and modern overview of geriatric neurosurgery. This volume compiles the latest research and clinical practice guidelines, offering practical advice for clinicians caring for elderly patients. It delves into a range of topics, including the management of common neurosurgical conditions in elderly patients, surgical techniques, postoperative care, and the integration of multidisciplinary approaches to enhance patient outcomes. Users will find this to be an invaluable reference for practicing neurosurgeons, neurosurgery residents, neurologists, geriatric physicians, and researchers seeking clear and concise information on current treatments and procedures for geriatric neurosurgery.

  • Engelking's Textbook of Veterinary Physiological Chemistry

    • 4th Edition
    • Kevin Connolly
    • English
    Bridging the gap between basic and clinical science concepts, Engelking's Textbook of Veterinary Physiological Chemistry, Fourth Edition offers broad coverage of biochemical principles for students and practitioners of veterinary medicine. The only recent biochemistry book written specifically for the veterinary field, this updated text covers cellular-level concepts related to whole-body physiologic processes in a reader-friendly, approachable manner. Each chapter is written in a succinct and concise style that includes an overview summary section, numerous illustrations for best comprehension of the subject matter, targeted learning objectives, and end of the chapter study questions to assess understanding.With numerous illustrations and both instructor and student companion websites with updated PowerPoint images, lecture slides, and Snapcasts, Engelking's Textbook of Veterinary Physiological Chemistry, Fourth Edition, proves useful to students and lecturers from diverse educational backgrounds. Sectional exams and updated case studies extend the breadth and depth of learning resources.

  • Advanced MR Techniques for Neurodegenerative Diseases

    • 1st Edition
    • Volume 14
    • Kannie Wy Chan + 3 more
    • English
    Advanced MR Techniques for Neurodegenerative Diseases covers state of the art developments in physiologic, metabolic, functional, and microstructural MRI of the brain. It provides an overview of these approaches and includes dynamic contrast enhanced (DCE) MRI, dynamic susceptibility contrast (DSC) MRI, arterial spin labeling (ASL), chemical exchange saturation transfer (CEST) MRI, magnetic resonance spectroscopy (MRS), resting state functional MRI (rsfMRI), microscopic diffusion imaging, and quantitative susceptibility mapping (QSM). Chapters then follow that present the application of these methods to Alzheimer’s Disease and vascular dementia, small vessel disease, Parkinson’s Disease, Lewy body dementia, Huntington’s Disease, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis.Advanced MR Techniques for Neurodegenerative Diseases is a comprehensive resource on the latest advanced MR techniques and their application to neurodegenerative diseases, suitable for MR engineers and physicists as well as clinicians and neuroscientists who use MR techniques for diagnosis and research.

  • Neuroscience-Informed Psychoeducation (NIPE) for Brain and Mental Health

    Part B
    • 1st Edition
    • Volume 301
    • English
    Neuroscience-Informe... Psychoeducation (NIPE) for Brain and Mental Health, Part B, Volume 300 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics such as Neuroscience-informe... Psychoeducation for Functional Neurological Disorder, Neuroscience-informe... Psychoeducation for Multiple Sclerosis, Neuroscience-informe... Psychoeducation for Neurodegenerative Disorders (Alz & PD) / Dementia, Neuroscience-informe... Psychoeducation for Traumatic Brain Injury, Neuroscience-informe... Psychoeducation for Epilepsy, Neuroscience-informe... Psychoeducation for Stroke, Neuroscience-informe... Psychoeducation for Movement Disorders, and much more.Additional chapters cover Neuroscience-informe... Psychoeducation for Therapy, Neuroscience-informe... Psychoeducation for Pharmacotherapy, Neuroscience-informe... Psychoeducation for Brain Stimulation, Neuroscience-informe... Psychoeducation for Cognitive Rehabilitation, Neuroscience-Informe... Psychoeducation as a Digital Neurotechnology Platform, Neuroscience-informe... Psychoeducation for Policy Making (Neurolaw), Neuroscience-informe... Psychoeducation to Promote Community Engagement, and more.

  • Histone Deacetylases in Neurodegenerative Disease Part B

    • 1st Edition
    • Volume 734
    • English
    Histone Deacetylases in Neurodegenerative Disease, Part B, Volume 734 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics surrounding the Interaction of HDAC6 ZnF UBP with Tau affects its stability by NMR and Simulation studies, Protocols for In Vitro Analysis of Liquid-Liquid Phase Separation of Proteins, Histone deacetylases in NS, Histone Deacetylase 6 ZnF UBP domain enhances podosome formation in neuronal cells studied by high-resolution confocal microscopy, Methodological approach to Investigate Peroxiredoxin 1 Deacetylation by Histone Deacetylase 6, Critical structural features of HDAC11 inhibitors, and much more.Additional chapters in this release include Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration, Elucidation of Site-Specific Ubiquitination on Chaperones in Response to Mutant Huntingtin, Protein acetylation dynamics (histone and non-histone) and role protein deacetylases in disease, Epigenetic Clues: Predicting Maternal Depression Through DNA Methylation, A short guide on in vivo transfection of flag-HDAC4 in dentate gyrus for study of adult neurogenesis in brain trauma, Decoding the Acetylation Journey from Neural Crest to Melanocyte, and more.

  • Encyclopedia of Psychotherapy

    • 2nd Edition
    • David Reitman + 1 more
    • English
    Traditional encyclopaedias present information in alphabetical order and are somewhat held hostage to a static structure. A digital reference can be sorted and organised more dynamically. We take advantage of this more flexible structure by cross-referencing contributions so that readers can create their own structure, one that suits their learning needs and those of their students and trainees. For example, a reader could select “child and adolescent” entries and directly cross-reference with “behavioural or cognitive/behavioura... In this edition all content is updated, and most content areas will be retained, focusing on major modes of psychotherapy practice and core psychotherapy processes. Outdated entries have been culled or combined with other entries in a manner that better communicates the content to present-day readers (e.g., “water-misting therapy” can be addressed in a more cohesive entry covering the use of punishment techniques more generally).

  • Advancing Sustainable Agriculture Through Arbuscular Mycorrhizal Fungi

    • 1st Edition
    • Allah Ditta + 2 more
    • English
    Advancing Sustainable Agriculture Through Arbuscular Mycorrhizal Fungi provides a comprehensive view of AMF-focused approaches that support biodiversity, ecosystem services, and soil health. The book addresses the topic from the basis of symbiosis to the latest research and future directions of AMF use in agriculture. It provides a thorough overview of the role that AM fungi play in promoting agricultural sustainability and synthesizes current knowledge on the biology, ecology, and applications of AM fungi in sustainable agriculture, highlighting best practices for promoting AM fungi in agricultural ecosystems, such as crop selection, soil management, and fertilizer use. In addition, the book identifies research gaps and priorities for the advancement of the understanding of AM fungi in sustainable agriculture. Among the major issues confronting agriculture are soil erosion, water shortages, climate change, and dwindling biodiversity. In response to these issues, the need for sustainable farming methods that support ecosystem services, biodiversity, and soil health is rising. As the soil microbiome is largely composed of arbuscular mycorrhizal (AM) fungi, which are essential for preserving soil health and encouraging plant development, this book is a welcomed resource.

  • Basic Principles of Drug Discovery and Development

    • 3rd Edition
    • Benjamin E. Blass
    • English
    **Selected for 2026 Doody's Core Titles in Pharmacy**Basic Principles of Drug Discovery and Development, Third Edition presents a unique overview of the drug discovery and development program not available elsewhere. Each chapter provides sufficient technical details on the topics covered so that non-experts will have the tools and information necessary to interact and exchange information with colleagues across the entire spectrum of the drug discovery and development process. The drug discovery and development process involves individuals and teams with a wide array of expertise ranging from basic sciences (medicinal chemistry, biology) to applied science (pharmacology, pharmacokinetics, clinical sciences) to business driven fields (regulatory affairs, intellectual property experts, marketing specialists).The success or failure of a program focused on bringing a new medication to market often depends on clear communication between individuals and teams with vastly different expertise. As a result, it is critical that experts in one aspect of drug discovery and development (e.g., medicinal chemists) have a working understanding of the wide range of disciplines that take part in the overall process.

  • Recent Advances in Targeting Inflammation

    Ion Channels, GPCR Signaling Tools, Therapies, and Beyond
    • 1st Edition
    • Senthilkumar Rajagopal + 3 more
    • English
    Recent Advances in Targeting Inflammation: Ion Channels, GPCR Signaling Tools, Therapies, and Beyond delves into the multifaceted occurrences of inflammation across different systems, such as neuroinflammation and gastric inflammation. The book's main goal is to present the latest highlights, covering advancements in inflammation, investigational therapies, animal models, and biomarkers. These insights are crucial for better diagnosis, monitoring, and potential therapeutic options for patients suffering from both acute and chronic inflammation. This comprehensive work explores various topics, including ion channel regulation in inflammation, GPCR regulation, signaling pathways, and therapeutic approaches.It emphasizes the importance of understanding the role of ion channels, GPCR, and nutrition in managing inflammation effectively. Additionally, the book discusses the global impact of chronic inflammation on health outcomes, stressing the need for improved healthcare planning and strategies.

  • The Science of Pharmacology

    • 1st Edition
    • Jahangir Moini + 3 more
    • English
    The Science of Pharmacology offers a detailed and contemporary exploration of medications, delving into the scientific principles behind drug actions and their therapeutic applications. It is an essential resource for students in pharmacology and pharmaceutical sciences, providing foundational knowledge on a wide range of topics. The book addresses the effects of drugs on various bodily systems, such as the nervous, respiratory, and cardiovascular systems, and also covers their impact on mental health and behavior. Beyond the core topics, the book also discusses special subjects like herbal medications and drug interactions.It includes valuable teaching materials, including test banks and quizzes, and offers comprehensive insights into toxicological treatments, making it an invaluable tool for both learning and teaching in the field.

  • Evaluating Oral Probiotics and Prebiotics

    • 1st Edition
    • Amir M. Mortazavian + 2 more
    • English
    Evaluating Oral Probiotics and Prebiotics reviews emerging applications of new probiotic strains, postbiotics, and production of key synbiotic generations. The book discusses successes and failures of viable probiotic ingestion, new trends and strains including genetically engineered probiotics, assessment of nonviable probiotics (postbiotics) and microflora benefits of prebiotic and synbiotic ingestion over probiotics.

  • Plant Polyphenols in the Food and Cosmetic Industries

    Extraction and Applications
    • 1st Edition
    • José Manuel Lorenzo
    • English
    Plant Polyphenols in the Food and Cosmetic Industries: Extraction and Applications explores the use of polyphenols in food and cosmetics. Broken into three parts, the book begins with coverage of extraction and purification processes before delving into specific food and cosmetic applications. Plant Polyphenols in the Food and Cosmetic Industries: Extraction and Applications provides nutrition researchers, food scientists, and plant scientists an opportunity to better understand the use of polyphenols in their industries.

  • Hormones in Neuroscience

    The Thyroid Gland and Thyroid Hormones
    • 1st Edition
    • Colin R. Martin + 3 more
    • English
    Hormones in Neuroscience: The Thyroid Gland and Thyroid Hormones explores the thyroid gland and thyroid hormones in-depth, presenting the latest research in neuroendocrinology and how it applies to translational and multidisciplinary methods. Covering different domains that bridge the physiological and medical divides between hormones and neurological tissues, this book will be a valuable resource for neuroendocrinologist... neuroscientists, pathologists, research scientists, and molecular or cellular biochemists in the field of hormone neuroscience.

  • Politics, Practice, and Policy

    How to Get Things Done in Food and Nutrition, 10 Case Studies
    • 1st Edition
    • Eileen Kennedy
    • English
    Food and Nutrition Policy: 10 Case Studies for Developing Effective Policies and Programs explains how policy compromises are reached and then changed over time as new information becomes available. Derived from the authors’ experiences while serving as a political appointee in the federal government, participating in international committees and boards, and from materials from a graduate course which she teaches on global food and nutrition policy at Tufts University, the 10 case studies presented in this book provide real world learning examples on how contentious issues are resolved in the political process.While each of the ten chapters focuses on a specific topic, the book showcases an overriding theme of food and health justice, equity, and empowerment. Readers will deduce key factors to examine pivotal policy decisions while the author dissects polarizing topics such as examining the successes and failures of dietary guidelines, front label packaging approaches, implications of expanding personalized nutrition, the obesity epidemic and the role of GMO’s in agricultural production, and more.

  • The Handbook of Autobiographical Memory

    From Basic to Applied Perspectives
    • 1st Edition
    • Mohamad El Haj + 2 more
    • English
    The Handbook of Autobiographical Memory: From Basic to Applied Perspectives offers a comprehensive view on autobiographical memory from a multidisciplinary approach. The book explores contemporary advances in understanding both cognitive and neural processes, including historical contexts on autobiographical memory theory and assessment. The book further synthesizes insights from cognitive, developmental, and social aspects of autobiographical functioning while also covering departures from norms in terms of autobiographical memory dysfunction. A section on applications equips readers with essential information regarding the assessment and detection of autobiographical memory dysfunction in neurological and psychiatric populations. How such processes evolve over the lifespan, and how deviations from healthy memory function can be supported through novel rehabilitation practices are also covered.

  • Body-on-a-Chip

    Essentials and Applications
    • 1st Edition
    • Anthony Atala + 1 more
    • English
    Body-on-a-Chip: Essentials and Applications provides the reader high-quality information, in a single resource, that is necessary to explore the use of BOC systems from design and development to testing and personalized medicine, to medical research and diagnostics. BOC systems can recapitulate native tissue/ organ architecture, diffusion kinetics of drugs physiological flow conditions etc., similar to what would happen in the body, they are particularly powerful in predicting human efficacy prior to clinical testing of a drug, determining potential toxicity, or in clinical studies to test underlying mechanisms or action or adverse effects. With recent advancements in high-throughput analysis systems and artificial intelligence, it has also become possible to screen several drugs at a time.

  • Motor Control Methods and Clinical Applications

    • 1st Edition
    • Robert Chen + 1 more
    • English
    Motor Control Methods and Clinical Applications provides a detailed review on the use of non-invasive brain stimulation to study motor control. Split into two distinct parts, this new volume covers the latest research in motor control, including real examples of these methods in a clinical setting. The first part covers advanced methods such as transcranial magnetic, electrical and ultrasound stimulation, long latency, spinal reflexes, multichannel EMG, and EEG-EMG analyses that can be used to examine and modulate the motor system. The second part of the book addresses the clinical applications of these methods.

  • The Dual Role of Inflammation in Cancer

    • 1st Edition
    • Surajit Pathak + 1 more
    • English
    The Dual Role of Inflammation in Cancer Genesis and Therapy explores the pivotal role inflammation plays in the development and progression of cancer. The book delves into how chronic inflammation creates a microenvironment that supports tumor growth by promoting cellular proliferation, survival, and migration while suppressing immune responses. It traces historical observations, linking inflammation to cancer while also examining how inflammatory cells and mediators contribute to various stages of tumorigenesis. In addition, it discusses the implications of inflammation on cancer treatment, highlighting the potential of anti-inflammatory agents and immunotherapy in targeting the inflammatory tumor microenvironment.By elucidating on the intricate relationship between inflammation and cancer, the book aims to pave the way for more effective and personalized cancer treatment strategies. As such, it is a valuable resource for researchers in immunology and oncology.

  • Microbial Exopolysaccharides

    An Integrated Approach to Green Applications
    • 1st Edition
    • Onkar Nath Tiwari + 2 more
    • English
    Microbial Exopolysaccharides: An Integrated Approach to Green Applications provides a comprehensive overview of natural exopolysaccharides (EPS) obtained from different microbial species and marine resources. Featuring contributions by an interdisciplinary group of experts in academia, research, and industry, this book offers a detailed introduction and exploration of natural microbial exopolysaccharides. It offers detailed discussions on topics such as the extraction and characterization of EPS, their role in health-promoting formulations and probiotic potential, their utilization in therapeutics, their use in food technologies and packaging, and their impact in the environmental and medical sectors.The book offers in-depth insights into the principles of EPS and their wide range of applications as sustainable solutions to challenges in the food, health, environmental, and biotechnology sectors.With a focus on green technology and sustainable practices, this book offers cost-effective utilization of natural EPS, their application in diverse sectors, and serves as an informative resource for those interested in the innovative application of natural bio-macromolecules.

  • Mathematical Foundations of Physiology, Medicine, and Health Sciences

    • 1st Edition
    • Dhanjoo N. Ghista + 3 more
    • English
    Mathematics and Biomedical Engineering in Medicine, Physiology and Health Sciences is a visionary book, whose purpose is to demonstrate how fundamental mathematics and biomedical engineering can be incorporated into physiology, medicine, and health sciences teaching, research,and clinical practice to make these disciplines more quantitative and computational, and hence more explanatory and informative. The book also provides more quantitative formulation of medical procedures, towards supporting the growing field of precision medicine.

  • The Honey Bee and Climate Change

    • 1st Edition
    • Gloria DeGrandi-Hoffman
    • English
    A honey bee colony is a community of interacting organisms continually adjusting their behaviors, both individually and collectively, in response to even the subtlest changes in the environment. It’s only logical then, that the more significant changes and stressors due to climate change will push the colony to its limits, disrupting the delicate balance of the hive and threatening the survival of the colony. Honey Bees and Climate Change is the first and only book to examine the responses of honey bees to climate change and the threat it poses to their ability to thrive and survive. Drawing on systems science and the central theme that all outcomes are products of an interconnected system, the book will address how climate change is affecting honey bee nutrition, growth, and overwinter survival, which in turn threaten commercial beekeeping and crop production. Impacts on other pollinators will be touched on as well. Finally, potential mitigating strategies, key areas of action, and the future outlook will be covered.Written by a leading scientist with over 40 years of experience studying honey bee physiology, nutrition, colony survival, and the impact of climate change on the colony, Honey Bees and Climate Change is crucial reading for students and researchers studying honey bees, especially those with an interest in the impacts of climate change on pollinators. The inclusion of key terms and definitions as well as case studies make this work an excellent supplementary text for courses on honey bee biology, apiculture, pollinator conservation, or climate change ecology.

  • Agricultural Pollination

    The Role of Beneficial Insects in Food Security and Sustainability
    • 1st Edition
    • Habib Ali
    • English
    Agricultural Pollination: The Role of Beneficial Insects in Food Security and Sustainability delves into the intricate relationship between farming and pollinators, as well as other beneficial insects, examining the ways in which their ecological roles can improve crop health and yield, ultimately bolstering food security without environmentally harmful chemical interventions. The book begins with coverage of foundational topics, such as types of key pollinators and their behaviors, and moves into more practical topics, such as creating pollinator-friendly landscapes and emerging technologies in pollination services.Taking a multidisciplinary approach, the book also covers conservation strategies, economic impacts of pollinators, policy recommendations, and community engagement. This timely reference will offer invaluable insights for researchers, students, agricultural industry professionals, and policymakers alike, contributing to the advancement of environmentally-frie... and economically viable agricultural practices.

  • The Future of Pharma Across All Sectors in the Artificial Intelligence Era

    • 1st Edition
    • Miltiadis Lytras + 5 more
    • English
    The Future of Pharma Across All Sectors in the Artificial Intelligence Era offers a thorough examination of the pharmaceutical industry's current landscape, highlighting the myriad challenges, opportunities, and trends that are poised to shape its future. Edited by experts, this book delves into transformative technological advancements, including artificial intelligence, machine learning, big data analytics, and blockchain. These technologies are redefining pharmaceutical research, development, and commercialization, making precision medicine and personalized therapies a reality, while integrating genomic medicine into the pharmaceutical value chain.Additionally, the book addresses educational implications for academic curricula, emphasizing the need for digital transformation in healthcare delivery models. It scrutinizes regulatory trends and compliance, offering insights into navigating complex landscapes to ensure product quality and safety. The book emphasizes the pharmaceutical industry's role in tackling infectious diseases and health disparities, promoting health equity through innovative drug development and access initiatives. Future trends and predictions are speculated upon, considering demographic shifts and evolving healthcare needs, while market dynamics and commercial strategies are analyzed to equip pharmaceutical companies with practical recommendations for navigating competitive landscapes.

  • Haptic Feedback Control in Medical Robotics

    • 1st Edition
    • Pushan Kumar Dutta + 4 more
    • English
    Haptic Feedback Control in Medical Robotics explores the transformative role of haptic technology on robotic surgical procedures, a vital area of innovation for biomedical engineers, covering their fundamental principles, practical applications, and the collaborative efforts required for their development. Through a blend of theoretical insights and real-world case studies, the book highlights how haptic feedback can restore sense of touch, enabling the execution of complex procedures with enhanced precision and safety. It serves as an indispensable resource for biomedical engineers and researchers, providing essential knowledge on the latest advancements, design challenges, and regulatory considerations surrounding haptic technology in medical robotics.By bridging the divide between engineering and clinical practice, it equips readers with the tools and understanding necessary for the future of surgical innovation, underscoring the critical role of tactile sensation in advancing robotic systems.

  • Hybrid Fluoroscopy and Ultrasound Guided Interventional Pain Procedures

    • 1st Edition
    • Manuel Herrero Trujillano + 4 more
    • English
    Hybrid Fluoroscopy and Ultrasound Guided Interventional Pain Procedures ameliorates the dearth of literature covering interventional pain procedures under both X-ray and ultrasound guidance. While existing resources focus on either modality separately, this book fills the gap by providing a consolidated approach, leveraging the strengths of both techniques. By doing so, it ensures practitioners have access to the most versatile and effective imaging methods available. This book is inherently practical, designed to serve as a go-to guide for clinicians facing real-world challenges in pain management. Its organization by body areas facilitates quick access to relevant techniques, while step-by-step guidance and visual aids ensure clarity and ease of understanding. By focusing on clinical relevance, the book empowers practitioners to implement evidence-based imaging interventions with confidence and precision. Hybrid Fluoroscopy and Ultrasound Guided Interventional Pain Procedures has the potential to make a meaningful impact on the field of pain management. By equipping practitioners with cutting-edge imaging techniques and insights, it promises to improve patient outcomes and advance the standard of care. Moreover, its global reach ensures that its benefits extend far beyond geographical boundaries, reaching pain medicine practitioners worldwide.

  • Advances in Digital Pathology and Artificial Intelligence in Pathology

    • 1st Edition
    • Anil V. Parwani + 1 more
    • English
    Advances in Digital Pathology and Artificial Intelligence in Pathology is a comprehensive resource in digital pathology and AI technologies and applications for practicing pathologists, pathology trainees, and computational pathology scientists. This is a must-have guide to understand and potentially implement these latest technologies during routine practice and research activities. As pathology has been transformed in recent years with the large-scale integration of digital technology and AI there has been a great deal of technologic and practical advancements. This book lays the foundation of understanding these technologies as well as applying them making the book essential in both practice and research.

  • Cyclodextrin Glucanotransferase

    A Comprehensive Guide from Gene to Applications
    • 1st Edition
    • Kiransinh Rajput
    • English
    Cyclodextrin Glucanotransferase: A Comprehensive Guide from Gene to Applications explores the essential role of cyclodextrin glucanotransferase (CGTase) in starch degradation and its diverse industrial applications. This book serves as a valuable resource for researchers and industry professionals, offering comprehensive insights from the genetic basis of CGTase to its practical applications. The book covers the production of CGTase by different bacterial genera, including Bacillus spp., and their purification strategies. It delves into the structural and functional characteristics of CGTase, highlighting its catalytic mechanisms, substrate specificity, and factors affecting enzyme activity and stability. Additionally, the book explores recombinant CGTases, their properties, and advancements in protein engineering and enzyme immobilization. With a strong focus on practical applications, the book discusses the remarkable properties of cyclodextrins, such as inclusion complex formation, and their wide range of uses in various industries, including pharmaceuticals, textiles, bioremediation, and food. Detailed case studies and real-world examples illustrate how CGTase and cyclodextrins can address specific challenges and drive innovation in these fields.This book is an essential resource for applied science researchers working in the field of starch processing enzymes, providing them with the knowledge to advance their research and development. It also serves as a valuable reference for researchers in the starch processing industries, offering insights into the latest advancements and practical applications of CGTase and cyclodextrins.

  • Microbial Technologies for Sustainable Waste Management

    • 1st Edition
    • Rajneesh Kumar + 2 more
    • English
    Microbial Technologies for Sustainable Waste Management explores advanced waste management through microbial processes. The book investigates the current limitations of traditional waste treatment and the potential for microbial cell factories in bringing innovative solutions to this field. Beginning with an introduction to the role of microbes in waste management, it examines global case studies demonstrating success stories in microbial waste treatment and microbial innovations for biotechnological applications in waste conversion. Concluding chapters focus on microbial pathways for anaerobic digestion, hydrolysis, and fermentation, and microbial technologies for industrial applications such as wastewater treatment and the biofuel industry.Additionall... the book considers microbial remediation of hazardous and toxic waste, microbial fuel cells, and strategies for plastic waste degradation. Emerging technologies, such as AI integration, microbial nanotechnology, and engineered microbes are discussed, along with their environmental impacts and potential for scaling up to commercial applications.

  • New Insights in Pediatric Holter Monitoring and Interpretation

    • 1st Edition
    • Gabriel Cismaru + 2 more
    • English
    New Insights in Pediatric Holter Monitoring and Interpretation is the cutting edge book required by pediatric cardiologists and other professionals who encounter arrhythmias in children. Holter ECG examination has recently undergone significant advances in technology, sensors, and software. Yet, these innovations have been considered primarily in the context of adult patients. On the contrary, New Insights in Pediatric Holter Monitoring and Interpretation uses a case-based methodology to illustrate diagnosis and management of actual pediatric patients. Further, it offers guidance in deciding when referrals are necessary for arrhythmological consultations or ablation interventions. This book also contains novel techniques for detecting and interpreting pediatric arrhythmias. These include the introduction of Poincare graphs, Lorenz plots, and other advanced methods for assessing heart rate variability. New Insights in Pediatric Holter Monitoring and Interpretation modernizes readers' understanding of arrhythmias in children, thus improving the young lives of those in their care.

  • CDK4/6 inhibitors in Breast Cancer Therapy

    • 1st Edition
    • Pankaj Kumar Singh + 3 more
    • English
    CDK4/6 inhibitors in Breast Cancer Therapy examines the pivotal role of CDK4/6 inhibition in treating hormone receptor-positive (HR+)/HER2-negative advanced breast cancer. The book highlights FDA-approved applications of these inhibitors alongside endocrine therapy and explores ongoing research into their potential as neoadjuvant treatments. It provides insights into the drug discovery and development of CDK4/6 inhibitors, covering their molecular mechanisms, pharmacology, and clinical applications. Chapters address their use in mono and adjuvant therapies, as well as challenges in targeting, while also discussing market potential and post-marketing safety issues.This book is a valuable resource for researchers and academics, enhancing understanding of CDK4/6 inhibitors' chemistry and therapeutic implications. By presenting detailed information on clinical trials and market formulations, it equips the audience with essential knowledge to navigate the complexities of targeted breast cancer therapies and contributes to advancing research in this critical area.

  • Cardiopulmonary Interactions in Sleep

    Comprehensive Approaches to Mitral Regurgitation and Sleep-Disordered Breathing
    • 1st Edition
    • Kyriakos Dimitriadis + 1 more
    • English
    Cardiopulmonary Interactions in Sleep: Comprehensive Approaches to Mitral Regurgitation and Sleep-Disordered Breathing delves into the correlation between these two serious conditions. Commonly found in patients with cardiovascular disease and heart failure, the interplay between mitral regurgitation and sleep-disordered breathing creates a vicious cycle of clinical deterioration. Their coexistence not only exacerbates disease severity but also increases mortality and adverse cardiovascular outcomes. This book addresses a significant gap in research by exploring this connection and offering insights into diagnosis and treatment.In addition to covering the diagnosis of these conditions, the book discusses coexistent pathologies such as arrhythmias and heart failure. It is the first to focus on the effects of surgical and transcatheter techniques on sleep-disordered breathing. The positive impact of these interventions on sleep respiration and the resulting benefits for mitral valve repair are meticulously analyzed, making it a valuable resource for understanding and treating these interconnected conditions.

  • The Principles and Practice of Medical Education

    Shaping the Future of Healthcare
    • 1st Edition
    • Sameer Mohommed Khan
    • English
    The Principles and Practice of Medical Education: Shaping the Future of Healthcare presents a comprehensive and methodical approach to the many dimensions of medical education, offering healthcare professionals a clear and practical introduction to core principles and applications. The book begins with an introduction that is followed by a focus on curriculum development and instructional methodologies that enhance learning. Sections on assessment and feedback, as well as quality in medical education, address the importance of evaluation and continuous improvement. The final section explores research in medical education, encouraging evidence-based practices and innovation.Together, these sections provide a clear and practical guide for improving teaching and learning in healthcare. Designed to bridge the existing gap in accessible and structured resources, the book explores the multifaceted nature of teaching, learning, assessment, and quality improvement, serving as both an introduction and a tool for advancing educational practices that ultimately support better healthcare outcomes for those working or studying in the field.

  • AI-Driven Cybersecurity for Intelligent Healthcare Systems

    • 1st Edition
    • Balamurugan Balusamy + 3 more
    • English
    AI-Driven Cybersecurity for Intelligent Healthcare Systems explores the intersection between AI, cybersecurity, and healthcare. The book offers detailed insights into the unique cybersecurity challenges faced by the healthcare sector and the role of AI in addressing these challenges. It presents case studies and real-world applications to illustrate the effectiveness of these solutions and highlights the significance of data privacy in healthcare and methods to ensure secure data sharing and storage. Topics such as federated learning, homomorphic encryption, and blockchain technology are covered to demonstrate how AI can enhance data security without compromising patient privacy.This book will be an essential resource for anyone involved in the healthcare industry, offering practical solutions and fostering a more in-depth understanding of how AI can revolutionize cybersecurity in healthcare.

  • Biosimilars and Biologics in Cancer Treatment

    An Era in Therapeutic Strategies
    • 1st Edition
    • Kuttiappan Anitha + 2 more
    • English
    Biosimilars and Biologics in Cancer Therapy: An Era in Therapeutic Strategies addresses challenges and opportunities in biosimilars and biologics, integrating the latest evidence, regulatory landscapes, economic implications, and strategies to enhance cancer management. The book aims to create an all-inclusive educational resource, bridge the gap between research and clinical practice, and inspire future research in oncology. It provides a comprehensive examination of cancer therapeutics, starting with an introduction to biologics and biosimilars, their historical development, and foundational principles. Sections explain mechanisms of action, drug development processes, regulatory landscapes, and clinical applications through case studies. Emerging therapeutic strategies, including combination therapies and personalized medicine, are also covered. This book benefits researchers, oncologists, pharmacologists, pathologists, and other healthcare professionals by offering up-to-date insights into the clinical aspects of biological medications and their biosimilars. Contributions from global experts ensure readers gain the latest advancements and practical guidance on integrating these therapies into clinical practice and research.

  • Functional and Virtual Medical 3D Imaging in Cardiovascular Medicine

    Education of the Novel Medical Approaches in Daily Clinical Practice
    • 1st Edition
    • Artur Rydosz + 2 more
    • English
    Functional and Virtual Medical 3D Imaging in Cardiovascular Medicine: Education of the Novel Medical Approaches in Daily Clinical Practice leverages cutting-edge technologies and innovative methodologies, such as 3D medical imaging, functional data analysis, and advanced educational frameworks to enhance clinical practice, medical research, and professional development in healthcare. Readers will learn to utilize enhanced diagnostic skills, discover how to implement immersive technologies into clinical workflows, and access resources for professional development, empowering them to stay current with advancements and elevate their clinical practice.Written by experts in the field for practicing clinicians, surgeons, and radiologists specializing in cardiology and cardiovascular medicine, as well as medical researchers and educators who are actively integrating advanced multimodal medical technologies into clinical diagnostics, treatment planning, and procedural training, this book provides an ideal reference for professional development in healthcare.

  • Neuroscience-Informed Psychoeducation (NIPE) for Brain and Mental Health

    Part A
    • 1st Edition
    • Volume 300
    • English
    Neuroscience-Informe... Psychoeducation (NIPE) for Brain and Mental Health series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Genome Damage

    Repair and Adaptation Across Life
    • 1st Edition
    • Vinod K. Kannaujiya + 2 more
    • English
    Genome Damage: Repair and Adaptation Across Life explores the significance of nucleic acid damage from environmental pollutants, UV radiation, and other stressors that can lead to mutations, genetic instability, and various diseases, including cancer. This book delves into the mechanisms of DNA and RNA repair, which are crucial for maintaining cellular health and enabling evolutionary adaptations. It examines these intricate processes across microbes, plants, and animals, providing a comprehensive understanding of how genetic materials are regulated and repaired under diverse environmental conditions.Other sections cover a wide range of topics, including advanced molecular mechanisms of nucleotide repair, UV-induced damage, apoptosis cell death and autophagy, genetic instability in crops, and the role of post-translational modifications in DNA repair, the detection and quantification of DNA damage, the impact of synthetic chemicals and climate change on nucleic acids, and the therapeutic significance of DNA repair mechanisms. The book closes with a look towards future perspectives.

  • Advanced Cancer Therapeutics

    Strategies and Technologies for Targeted Drug Delivery
    • 1st Edition
    • Manish Kumar + 2 more
    • English
    Advanced Cancer Therapeutics: Strategies and Technologies for Targeted Drug Delivery explores the heterogeneity of tumors and microenvironmental factors that influence cancer treatment and contribute to drug resistance. The book discusses critical elements such as tumor stroma, vasculature, pH, hypoxia, and enzymatic activity that impact therapeutic efficacy. Sections cover advanced drug formulations, including supramolecular systems, metal-organic frameworks, and nanomedicine, focusing on their roles in selective drug delivery for early detection, diagnosis, and treatment of various cancers. In addition, it reviews the current status and future perspectives of these formulations, highlighting their potential to enhance therapeutic outcomes while minimizing side effects.Readers will also find discussions on the limitations of nanocarriers, along with regulatory and ethical considerations related to anticancer formulations. This resource is invaluable for researchers, clinicians, and students, offering insights into the latest advancements in drug delivery systems.

Related subjects