The Dual Role of Inflammation in Cancer
- 1st Edition - September 1, 2026
- Latest edition
- Editors: Surajit Pathak, Antara Banerjee
- Language: English
The Dual Role of Inflammation in Cancer Genesis and Therapy explores the pivotal role inflammation plays in the development and progression of cancer. The book delves into how ch… Read more
The Dual Role of Inflammation in Cancer Genesis and Therapy explores the pivotal role inflammation plays in the development and progression of cancer. The book delves into how chronic inflammation creates a microenvironment that supports tumor growth by promoting cellular proliferation, survival, and migration while suppressing immune responses. It traces historical observations, linking inflammation to cancer while also examining how inflammatory cells and mediators contribute to various stages of tumorigenesis. In addition, it discusses the implications of inflammation on cancer treatment, highlighting the potential of anti-inflammatory agents and immunotherapy in targeting the inflammatory tumor microenvironment.
By elucidating on the intricate relationship between inflammation and cancer, the book aims to pave the way for more effective and personalized cancer treatment strategies. As such, it is a valuable resource for researchers in immunology and oncology.
By elucidating on the intricate relationship between inflammation and cancer, the book aims to pave the way for more effective and personalized cancer treatment strategies. As such, it is a valuable resource for researchers in immunology and oncology.
- Provides a comprehensive understanding of the molecular and cellular mechanisms by which inflammation contributes to tumor initiation, progression, and metastasis
- Combines historical perspectives, scientific research, and clinical insights to create a holistic understanding of the complex relationship between inflammation and cancer
- Delves into cutting-edge developments, including the latest advancements in cancer immunotherapy and novel approaches to modulating the tumor microenvironment through inflammation modulation
Researchers working across the biosciences in the field of oncology and immunology
1. Introduction to Inflammation and Cancer
2. Chronic Inflammation and Cancer: Epidemiological Evidence
3. Role of Inflammatory Cells in Cancer Development
4. The Tumor Microenvironment and Inflammation
5. Cytokines and Chemokines in Tumorigenesis and Their Pro-tumorigenic and Anti-tumorigenic Roles in Cancer Development
6. The Role of Oxidative Stress in Inflammation-Mediated Cancer Progression Inflammation and Metastasis
7. Genetic and Epigenetic Changes Driven by Inflammation
8. Epigenetic Signaling: Regulation of Inflammation in Cancer
9. Inflammation and Tumor Progression: Signaling Pathways
10. Biomarkers and Signaling Pathways of Inflammation-Mediated Cancer Development: Promising Targets to Limit
11. Metastatic Potential and Stemness
12. Anti-inflammatory Agents in Cancer Prevention and Therapy
13. Tumor-Infiltrating Inflammatory Cells as Possible Therapeutic Targets
14. The Inflammatory Chemokines and in Malignancy: Leukocyte Migration and Beyond
15. Inflammation and Beyond: Complex Roles for TGF-β in the Tumor Microenvironment
16. Microenvironmental Mediators as Therapeutic Targets in Malignancy
17. Role of Macrophages in Regulating Tumor Angiogenesis: Implications for Cancer Therapy
18.Immune Forces Impacting DNA-Based Cancer Immunotherapeutic Strategy
19. Immunotherapy and Inflammation
20.Case Studies: Inflammation-targeted Cancer Therapies
21. Microbiota, Inflammation and Colorectal Cancer
22. Genomics and Microbiome and Their Immunotherapy Implications in Cancer
23. Modulation of Tumor Immunogenicity
24. Biomarkers Associated with Immunotherapeutic Response in Cancer
25. Endoscopy and AI in the Diagnosis and Early Detection of Dysplastic Lesions
26. Chemopreventive Strategies for Inflammation-Related Carcinogenesis: Current Status and Future Direction
27.Combinational Immunotherapy Against Cancer
28. Policy Recommendations Regarding Immunotherapy and Other Cancer Therapy
2. Chronic Inflammation and Cancer: Epidemiological Evidence
3. Role of Inflammatory Cells in Cancer Development
4. The Tumor Microenvironment and Inflammation
5. Cytokines and Chemokines in Tumorigenesis and Their Pro-tumorigenic and Anti-tumorigenic Roles in Cancer Development
6. The Role of Oxidative Stress in Inflammation-Mediated Cancer Progression Inflammation and Metastasis
7. Genetic and Epigenetic Changes Driven by Inflammation
8. Epigenetic Signaling: Regulation of Inflammation in Cancer
9. Inflammation and Tumor Progression: Signaling Pathways
10. Biomarkers and Signaling Pathways of Inflammation-Mediated Cancer Development: Promising Targets to Limit
11. Metastatic Potential and Stemness
12. Anti-inflammatory Agents in Cancer Prevention and Therapy
13. Tumor-Infiltrating Inflammatory Cells as Possible Therapeutic Targets
14. The Inflammatory Chemokines and in Malignancy: Leukocyte Migration and Beyond
15. Inflammation and Beyond: Complex Roles for TGF-β in the Tumor Microenvironment
16. Microenvironmental Mediators as Therapeutic Targets in Malignancy
17. Role of Macrophages in Regulating Tumor Angiogenesis: Implications for Cancer Therapy
18.Immune Forces Impacting DNA-Based Cancer Immunotherapeutic Strategy
19. Immunotherapy and Inflammation
20.Case Studies: Inflammation-targeted Cancer Therapies
21. Microbiota, Inflammation and Colorectal Cancer
22. Genomics and Microbiome and Their Immunotherapy Implications in Cancer
23. Modulation of Tumor Immunogenicity
24. Biomarkers Associated with Immunotherapeutic Response in Cancer
25. Endoscopy and AI in the Diagnosis and Early Detection of Dysplastic Lesions
26. Chemopreventive Strategies for Inflammation-Related Carcinogenesis: Current Status and Future Direction
27.Combinational Immunotherapy Against Cancer
28. Policy Recommendations Regarding Immunotherapy and Other Cancer Therapy
- Edition: 1
- Latest edition
- Published: September 1, 2026
- Language: English
SP
Surajit Pathak
Prof. Surajit Pathak, PhD, is a professor at Chettinad Academy of Research and Education (CARE), Chennai, India since 2015. He was previously a principal research scientist (2022 June–Dec 2022) at Linkoping University, Linkoping, Sweden. He received his PhD degree from India in 2007 and completed his postdoctoral training (2007–15) from the University of Alabama, United States, the University of Padova, Italy, and the University of Linkoping, Sweden. His current research focuses on “Biomarker discoveries for early detection of colorectal cancer.” He has published more than 100 research articles in peer-reviewed international journals of repute with 2233 citations and 27 H-index. Dr. Pathak has edited Elsevier book “Stem Cells and Aging” in 2021. He is the member of various professional research bodies of India, including the Indian Association of Cancer Research and the Indian Science Congress.
Affiliations and expertise
Professor, Chettinad Hospital and Research Institute, Chettinad Hospital and Research Institute (CHRI), Chettinad Academy of Research and Education (CARE), Kelambakkam, Chennai, IndiaAB
Antara Banerjee
Dr. Antara Banerjee, PhD, is presently working as an associate professor at CARE, Chennai from 2016 to date. After completing her PhD in 2008 from India, Dr. Banerjee pursued her postdoctoral work at the University of Padova, Italy and Linkoping University, Sweden (2009–15). She has published over 95 peer-reviewed research articles in international and national journals with citation index-1408 and H-index 19. The Banerjee’s lab at Chettinad Hospital and Research Institute is now focused on understanding the role of mesenchymal stem cells niche in tissue regeneration and exploring signaling pathways in governing stem cell fate. She is the editor of Elsevier book “Stem Cells and Aging” in 2021. She is the member of various professional research bodies, including the Indian Association of Cancer Research and the Indian Science Congress.
Affiliations and expertise
Associate Professor, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education (CARE), Kelambakkam, Chennai, India