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Elsevier

Hormones in Neuroscience

The Thyroid Gland and Thyroid Hormones

  • 1st Edition - September 14, 2026
  • Latest edition
  • Editors: Colin R. Martin, Vinood B. Patel, Victor R. Preedy, Rajkumar Rajendram
  • Language: English

Hormones in Neuroscience: The Thyroid Gland and Thyroid Hormones explores the thyroid gland and thyroid hormones in-depth, presenting the latest research in neuroe… Read more

Description

Hormones in Neuroscience: The Thyroid Gland and Thyroid Hormones explores the thyroid gland and thyroid hormones in-depth, presenting the latest research in neuroendocrinology and how it applies to translational and multidisciplinary methods. Covering different domains that bridge the physiological and medical divides between hormones and neurological tissues, this book will be a valuable resource for neuroendocrinologists, neuroscientists, pathologists, research scientists, and molecular or cellular biochemists in the field of hormone neuroscience.

Key features

  • Explains thyroid hormones in relation to the nervous system, with a multidisciplinary approach
  • Distills important information at the end of each chapter in summary points
  • Explores the thyroid gland and thyroid hormones in-depth, presenting the latest research in neuroendocrinology, and its application into clinical settings

Readership

Neuroendocrinologists, neuroscientists, pathologists, research scientists, and molecular or cellular biochemists in the field of hormone neuroscience

Table of contents

Section 1: Introductory Chapters

1. An introduction to the Thyroid Gland

2. Thyroid Hormones: An Introduction

3. Enzymes Involved in Thyroid Hormones Metabolism and Status

4. Diseases of the Thyroid Gland and Thyroid Hormone Production: Autoimmunity and Beyond

Section 2: Psychology and Behavior as a Consequence of Changes in Neurological Tissues

5. Free Thyroxine and Psychosis

6. Hypothyroidism and Impact on Anxiety and Depression

7. Mental State and Thyroid Hormones: Bipolar Disorder

8. Thyroid Patients and Adverse Psychological Impact of COVID-19 Related Lockdown

9. Thyroidectomy and Quality of Life Domains

Section 3: Focused Areas of Neurological Pathology and Physiology

10. 3,3',5-Triiodothyroacetic Acid and Effects on Cerebrum

11. Brain Demyelination, Remyelination and Thyroid Hormones

12. Environmental Toxicants, Thyroid Hormones and Gene Expression in the Brain

13. The Thyroid Hormone Transporter, Transthyretin (TTR) and Effects of Stress on the Brain

14. Thyroid Hormones and the Hippocampus in Alzheimer's Disease

15. Thyroid Hormones and the Hypothalamus

16. Thyroid Signaling and Glial Cells

Section 4: Treatment Regimens Modulating Thyroid Status and Effects on Neurological Tissues

17. Levothyroxine and Effects on the Brain: MRI and Beyond

18. Levothyroxine Treatments in Pregnancy and Impact on Cognition in Offspring

19. Nomedicines with Promyelinating Agent Triiodothyronine

Section 5: Non-Thyroid Treatment Regimens

20. Alemtuzumab and Impact on Autoimmune Thyroid Dysfunction

21. Changes in Thyroid Status in Response to Drugs Used in Epilepsy: A New Narrative

22. Lithium Use in Mental Health and Impact on Thyroid Status

Section 6: Diseases of the Thyroid or Thyroid Status And Impact On Brain And Behavior

23. Hashimoto Thyroiditis and Blood Flow to the Brain

24. Hashimoto's Thyroiditis: Linking Anxiety and Depression

25. Postpartum Thyroiditis and Links with Depression

Section 7: Diet and Nutrition and Impact on Thyroid Status and Neuroscientific Domains or Behavior

27. Arginine and Endocrine Status: A Focus on Thyroid Hormones

28. Brain Damage in Hyperthyroidism: Effect of Nutraceuticals

29. Iodine in Pregnancy and Brain of Offspring

30. Resveratrol and Related Polyphenols: Impact on TRH in Neurological Tissues

31. Thyroid Function and Postnatal Depression

Product details

  • Edition: 1
  • Latest edition
  • Published: September 21, 2026
  • Language: English

About the editors

CM

Colin R. Martin

Colin R. Martin RN, BSc, MSc, PhD, MBA, YCAP, FHEA, C.Psychol, AFBPsS, C.Sci is Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director of the Institute of Health and Wellbeing at the University of Suffolk, UK. He is a Chartered Health Psychologist and a Chartered Scientist. He also trained in analytical biochemistry, this aspect reflecting the psychobiological focus of much of his research within mental health. He has published or has in press well over 300 research papers and book chapters. He is a keen book author and editor having written and/or edited more than 50 books. These outputs include the prophetic insight into the treatment of neurological disease, Handbook of Behavior, Food and Nutrition (2011), Nanomedicine and the Nervous System (2012), Oxidative Stress and Dietary Antioxidants in Neurological Disease (2020), Zika Virus Impact, Diagnosis, Control and Models (2021), Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior and Diet (2021), Diagnosis and Treatment of Spinal Cord Injury (2022), The Neurobiology, Physiology, and Psychology of Pain (2022) and The Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging (2023). Professor Martin is particularly interested in all aspects of the relationship between underlying physiological substrates and behavior, particularly in how these relationships manifest in both acute and chronic psychiatric disorder. He has published original research germane to significant mental health disorders including the areas of schizophrenia, anxiety, depression, self-esteem, alcohol and drug dependency, high secure forensic mental health and personality disorder. He has a keen interest in the impact of postviral illness and is actively involved in clinical research post-Covid pandemic and in particular, the impact of Long Covid on psychological, neurological, physiological and social functioning. He is involved in collaborative International research with many European and Non-European countries.
Affiliations and expertise
Visiting Professor of Perinatal Wellbeing, Institute for Health and Wellbeing, University of Suffolk, Ipswich, UK

VP

Vinood B. Patel

Vinood B. Patel, BSc, PhD, FRSC, is Professor in Clinical Biochemistry at the University of Westminster. In 2014 Dr Patel was elected as a Fellow to The Royal Society of Chemistry. Dr Patel graduated from the University of Portsmouth with a degree in Pharmacology and completed his PhD in protein metabolism from King’s College London in 1997. His postdoctoral work was carried out at Wake Forest University Baptist Medical School, NC, USA studying structural-functional alterations to mitochondrial ribosomes, where he developed novel techniques to characterize their biophysical properties. Research is being undertaken to study the role of nutrients, antioxidants, phytochemicals, iron, alcohol and fatty acids in the pathophysiology of disease. Other areas of interest are identifying new biomarkers that can be used for the diagnosis and prognosis of disease and understanding mitochondrial oxidative stress. Dr Patel is a nationally and internationally recognized researcher and has several edited biomedical books related to health and well being These books include Ancient and traditional foods, plants and herbs and spices in human health; coffee in health and disease prevention, Nuts and seeds in health and disease prevention Handbook of Substance Misuse and Addictions: From Biology to Public Health, tea in health and disease prevention.

Affiliations and expertise
Professor, Clinical Biochemistry, School of Life Sciences University of Westminster, London, UK

VP

Victor R. Preedy

Professor Preedy has been elected as a Fellow to the following Royal Societies: The Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health and Hygiene, the Royal Society for Public Health, the Royal Society of Chemistry, and the Royal Society of Medicine. He was founding Director of the Genomics Centre at King’s College London and held the post from 2006 to 2020. He is a leading expert on the science of health and has a long-standing interest in disease processes, biomarkers, and tissue pathology. He has lectured nationally and internationally. Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.
Affiliations and expertise
Professor, Clinical Biochemistry, King’s College Hospital, London, UK; Emeritus Professor, Faculty of Life Sciences and Medicine, King’s College London, UK; Visiting Professor of Health Sciences, University of Suffolk, UK

RR

Rajkumar Rajendram

Dr Rajkumar Rajendram is a clinician-scientist with expertise in internal medicine, anaesthesia, intensive care and peri-operative medicine. He graduated with distinctions from Guy’s, King’s and St Thomas’ Medical School, King’s College London, in 2001, where he received several prizes, merits and distinctions in pre-clinical and clinical subjects.

Dr Rajendram completed specialist training in acute and general medicine in Oxford and subsequently held a Consultant appointment in Acute General Medicine at the John Radcliffe Hospital, Oxford. He also trained in anaesthesia and intensive care in London, including advanced training in regional anaesthesia and intensive care, and subsequently held a Consultant appointment in Intensive Care, Anaesthesia and Peri-operative Medicine at the Royal Free London Hospitals.

His postgraduate training has spanned internal medicine, anaesthesia, intensive care and point-of-care ultrasound (POCUS). He was awarded Fellowship of the Royal College of Anaesthetists in 2009, Fellowship of the Faculty of Intensive Care Medicine in 2013, and the European Diploma in Intensive Care Medicine in 2014. He is a Fellow of both the Royal College of Physicians of Edinburgh and the Royal College of Physicians of London.

Dr Rajendram is currently a Consultant at King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia, and holds a joint appointment as Associate Professor in the Research Unit, Department of Medical Education, at King Saud bin Abdulaziz University for Health Sciences.

His multidisciplinary clinical background has informed his research interests in nutrition, fluid management and fluid balance in health and disease, particularly in acutely and critically ill patients. His research has also addressed POCUS, COVID-19 phenotypes and nutritional support in illness. Dr Rajendram has contributed extensively to medical research and education and has authored more than 400 textbook chapters, review articles, peer-reviewed papers and conference abstracts.

Affiliations and expertise
Consultant, Medical Protocol Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia & Joint Appointment Associate Professor, Research Unit, Department of Medical Education, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia

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