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Elsevier

Books in Life sciences

  • In Vitro Biological Systems

    Methods in Toxicology, Vol. 1
    • 1st Edition
    • Charles A. Tyson + 1 more
    • English
    Methods in Toxicology, Volume 1: In Vitro Biological Systems, Part A provides basic techniques employed by widely recognized scientists to prepare and maintain the biological components of in vitro model systems. The book discusses the in vitro models of neural and neuromuscular systems; ocular system; respiratory system; cardiovascular system; and gastrointestinal system. The text also describes liver slices; liver hepatocytes; other liver cell systems; proximal tubule fragments; kidney cell culture; reproductive and developmental systems; immune system; and skin. Pharmacologists, toxicologists, cell biologists, physiologists, immunotoxicologists, and molecular toxicologists will find the book invaluable.

  • Nutrition and Lactation in the Dairy Cow

    • 1st Edition
    • Philip C. Garnsworthy
    • English
    Nutrition and Lactation in the Dairy Cow is the proceedings of the 46th University of Nottingham Easter School in Agricultural Science. Said symposium was concerned with the significant advances in the field of nutrition and lactation in the dairy cow. The book is divided in five parts. Part I deals with the principles behind nutrition and lactation of cows. Part II discusses the cow’s nutrient interactions; responses to nutrients that yield protein and energy; and the influence of nutrient balance and milk yields. Part III tackles the efficiency of energy utilization in cows and its relation to milk production. Part IV talks about food intake of cows and the factors that affect it, while Part V deals with the different feeding systems for cows. The text is recommended for those involved in raising cows and dairy production, especially those who would like to know more and make studies about the relationship of nutrition and lactation of cows.

  • Pharmacology of Central Synapses

    • 1st Edition
    • V. V. Zakusov
    • English
    Pharmacology of Central Synapses deals with the pharmacology of the central nervous system and the mode of action of neurotropic drugs based on their influence on synaptic transmission. The neuronal structure of the nervous system, the structure of the synapses, and the phenomena of electrochemical transmission are discussed in this context. The main propositions of the synaptic theory of the action of neurotropic drugs, based on morphological, physiological, and biochemical findings, form the conceptual basis of this book. Comprised of eight chapters, this book examines the effect of neurotropic drugs on the synaptic transmission in reflex, projection, and association (commissural) tracts. The specific effects of various narcotics, neuroleptics, tranquillizers, analgesics, antidepressants, and stimulants on synaptic transmission in various structures of the central nervous system and at its different levels are described. This text also considers the differences in the sensitivity to such drugs of various synapses and their influence on the selectivity of drug action. This book explains the influence of neurotropic drugs on such aspects of nervous activity as impulse summation, after-discharge and functional lability, central inhibition, and the neurochemical mechanisms, particularly those involving monoaminergic, cholinergic, serotoninergic, and GABA-ergic components of synaptic transmission. The final chapter focuses on the effect of psychotropic drugs on behavior. This book will be helpful to scientists representing all the major areas of pharmacology, including clinical pharmacology and toxicology, as well as to internists, psychiatrists, neurologists, and anesthesiologists.

  • The Exergy Method of Thermal Plant Analysis

    • 1st Edition
    • T. J. Kotas
    • English
    The Exergy Method of Thermal Plant Analysis aims to discuss the history, related concepts, applications, and development of the Exergy Method - analysis technique that uses the Second Law of Thermodynamics as the basis of evaluation of thermodynamic loss. The book, after an introduction to thermodynamics and its related concepts, covers concepts related to exergy, such as physical and chemical exergy, exergy concepts for a control method and a closed-system analysis, the exergy analysis of simple processes, and the thermocentric applications of exergy. A seven-part appendix is also included. Appendices A-D covers miscellaneous information on exergy, and Appendix E features charts of thermodynamic properties. Appendix F is a glossary of terms, and Appendix G contains the list of references. The text is recommended for physicists who would like to know more about the Exergy Method, its underlying principles, and its applications not only in thermal plant analysis but also in certain areas.

  • Interlimb Coordination

    Neural, Dynamical, and Cognitive Constraints
    • 1st Edition
    • Stephan P. Swinnen + 3 more
    • English
    This comprehensive edited treatise discusses the neurological, physiological, and cognitive aspects of interlimb coordination. It is unique in promoting a multidisciplinary perspective through introductory chapter contributions from experts in the neurosciences, experimental and developmental psychology, and kinesiology. Beginning with chapters defining the neural basis of interlimb coordination in animals, the book progresses toward an understanding of human locomotor control and coordination and the underlying brain structures and nerves that make such control possible. Section two focuses on the dynamics of interlimb coordination and the physics of movement. The final section presents information on how practice and experience affect coordination, including general skill acquisition, learning to walk, and the process involved in rhythmic tapping.

  • Pathogenesis of Leprosy and Related Diseases

    • 1st Edition
    • D. S. Ridley
    • English
    Pathogenesis of Leprosy and Related Diseases provides insights into the pathology of granulomatous conditions. The book discusses topics on the factors that induce immunosuppression; immunohistological spectra of granulomatous diseases; study of cutaneous leishmaniasis; and the validity of histopathological analysis. Pathologists, immunologists, experimentalists, and researchers in the medical field will find the book interesting.

  • Chemical Manipulation of Crop Growth and Development

    Proceedings of Previous Easter Schools in Agricultural Science
    • 1st Edition
    • J S McLaren
    • English
    Chemical Manipulation of Crop Growth and Development presents a critical review of the plant growth regulators in field crops. It discusses the strategies to discover plant growth regulators for agronomic crops; the methods of modifying stomatal movement; and the possible use of chemicals for photorespiration control. Some of the topics covered in the book are the hormonal control of photosynthesis and assimilate distribution; manipulation of crop growth by ethylene and some implications of the mode of generation; genetic and chemical manipulation of crops to confer tolerance to chemicals; and effects of allelochemicals on crop growth and development. The control of development of potato plant by using endogenous and exogenous growth regulators is covered. The analysis of crop physiology to assess plant growth regulation in sugar beet is also discussed. An in-depth analysis of the influence of auxin antagonists on pod and seed number is provided. The effect of foliar applications of synthetic plant growth regulators on the agronomic characteristics of field-growth corn is presented. A chapter is devoted to the use and effect of cerone in developing winter barley. The book can provide useful information to farmers, botanists, students, and researchers.

  • Infections of the Nervous System

    Butterworths International Medical Reviews
    • 1st Edition
    • Peter G. E. Kennedy + 1 more
    • English
    Infections of the Nervous System aims to continue the legacy of its predecessor, Modern Trends in Neurology. Its goal is to produce annually a monograph on a topic in clinical neurology in which progress through research has brought about new concepts of patient management. This book is organized into 13 chapters. It highlights the areas or subjects in which significant advances have been made which also have relevance to the treatment of patients. It covers a number of important aspects of different infectious diseases of the nervous system including acute bacterial meningitis, tuberculosis of the nervous system, spirochaetal infections of the nervous system, and fungal diseases of the central nervous system. This book is intended for use by physicians who deal with the problems of neurological disorder on a daily basis, whether they are neurologists, neurologists in training, or those in related fields such as neurosurgery, internal medicine, psychiatry, and rehabilitation medicine.

  • Kinetic Theory of Nonideal Gases and Nonideal Plasmas

    International Series in Natural Philosophy
    • 1st Edition
    • Yu L Klimontovich
    • D. ter Haar
    • English
    Kinetic Theory of Nonideal Gases and Nonideal Plasmas presents the fundamental aspects of the kinetic theory of gases and plasmas. The book consists of three parts, which attempts to present some of the ideas, methods and applications in the study of the kinetic processes in nonideal gases and plasmas. The first part focuses on the classical kinetic theory of nonideal gases. The second part discusses the classical kinetic theory of fully ionized plasmas. The last part is devoted to the quantum kinetic theory of nonideal gases and plasmas. A concluding chapter is included, which presents a short account of the kinetic theory of chemically reacting systems and of partially ionized plasmas, in order to espouse further studies in the field. Physicists, scientific researchers, professors, and graduate students in various fields will find the text of good use.

  • Evaluating Alcohol and Drug Abuse Treatment Effectiveness

    Recent Advances
    • 1st Edition
    • Linda Carter Sobell + 2 more
    • English
    Evaluating Alcohol and Drug Abuse Treatment Effectiveness: Recent Advances is a collection of papers that covers the advancement in rehabilitation of individuals with a history of substance abuse. The title aims to find ways in identifying the treatment that best fits a specific patient. The text first provides a historical account of alcohol and drug treatment outcome research. Next, the selection considers the use of multiple measures of life health to assess alcohol treatment. Chapter 3 deals with the behavioral assessment and treatment evaluation of narcotic addiction, while Chapter 4 talks about the evaluation of behavioral and traditional treatment of alcoholics. The fifth chapter tackles the contingency contracting with drug abusers, and the sixth chapter covers the development of a prototype for the evaluation of alcohol treatment. The text also details the problems in alcohol treatment along with the improvement of confidence in treatment of substance abuse. The book will be of great use to behavioral scientists, social workers, and mental health specialists.

  • The Manual of Australian Agriculture

    • 1st Edition
    • Robert L Reid
    • English
    The Manual for Australian Agriculture is a collection of information related to agriculture gathered from different Australian government agencies that are directly or indirectly concerned with agriculture. The book covers related topics such as land utilization and resource use; government assistance to Australian farmers; the physical and chemical properties of soil; soil mapping; plant nutrition, and fertilizers; and the growing of grain crops. The book also covers agro-industrial, fruit, and vegetable crops; kinds of seeds and their processing and storage; plant pests and diseases; and livestock and poultry. The text is recommended for agriculturists who are engaged in business, as well as those who would like to know more about agriculture in Australia.

  • Antibody Techniques

    • 1st Edition
    • Vedpal S. Malik + 1 more
    • English
    The applicability of immunotechniques to a wide variety of research problems in many areas of biology and chemistry has expanded dramatically over the last two decades ever since the introduction of monoclonal antibodies and sophisticated immunosorbent techniques. Exquisitely specific antibody molecules provide means of separation, quantitative and qualitative analysis, and localization useful to anyone doing biological or biochemical research.This practical guide to immunotechniques is especially designed to be easily understood by people with little practical experience using antibodies. It clearly presents detailed, easy-to-follow, step-by-step methods for the widely used techniques that exploit the unique properties of antibodies and will help researchers use antibodies to their maximum advantage.

  • Urine Analysis

    • 1st Edition
    • Byomkes Das Gupta
    • English
    Urine Analysis presents the theory and methods of urine analysis, which serves as a guide for physicians and medical laboratory technicians. Topics discussed in the book include the physical examination of urine; its chemical examination; microscopical examination; and Ehrliches Diazo reaction. Physicians and medical laboratory technicians will find the book a very valuable reference material.

  • Protides of the Biological Fluids

    Proceedings of the Sixteenth Colloquium, Bruges, 1968
    • 1st Edition
    • H. Peeters
    • English
    Protides of the Biological Fluids presents the functional approach to conformation that combines the physiological significance with physical and chemical appearance of the protein. This book discusses the technical details of purification, determination, or identification of given protein fractions. Organized into three sections, this book begins with an overview of the intramolecular cross-linked synthetic polypeptides that can be used as models for the organized spatial structure of proteins. This text then examines the polarization of fluorescence methods, which provide very sensitive hydrodynamic techniques for studying the internal organization and the rigidity of the polypeptide. Other sections consider the excretion of different classes of immunoglobulins in the external secretions of dogs. This book discusses as well the anti-coli antibody and the poliovirus neutralizing antibody activity of achlorhydric gastric juices. The final section deals with the introduction of gels as a medium for the electrophoresis of proteins. This book is a valuable resource for chemists, biochemists, and geneticists.

  • Honey Bee Pathology

    • 2nd Edition
    • Larissa Bailey + 1 more
    • English
    Since the publication of the first edition of this book in 1982, investigation into the pathology of honey bees has progressed considerably. Furthermore, several different agents of disease, some newly discovered, have been causing increasing concern in recent years in many parts of the world.The book contains separate chapters on viruses, bacteria, fungi, protozoa, mites, nematode and insect parasites, non-infectious diseases, and the treatment of diseases. The contents are a thorough revision of the previous edition and incorporate much new information, especially with respect to viruses, bacteria, fungi, and mites. Specific organisms, such as the mite Varroa jacobsoni and the secondary diseases resulting from its presence, are considered in detail.Knowledge of the subject is central to well-managed beekeeping, an industry that, besides producing honey and wax for man, is increasingly valuable ecologically for pollinating wild as well as cultivated plants. Apart from its value for beekeeping and apicultural research, this book will also be of interest to ecologists, microbiologists, virologists, parasitologists, and general entomologists.

  • Dale's an Introduction to Social Biology

    • 4th Edition
    • Susan Dale
    • English
    Dale's an Introduction to Social Biology, Fourth Edition deals with the more practical context of teaching modern science in the background of human activity. This book discusses life in the context of dynamic space and evolving time: from Paleontological times to evidence found in blood precipitin test, as well as proof from the variability of plants and animals. This text describes man as animal that needs to maintain its species through sex, inheritance, and reproduction. This book also addresses social hygiene, health, and the history of medicine including diagnostics, germ theory, recognition of vectors of diseases, new curative agents, hospitals, and public health measures. This text describes the function of proteins, carbohydrates, fats, and emphasizes the importance of maintaining the balance of nature. This book discusses the social life of animals, human population, human food production, and offers some reason why man has been so successful in terms of survival. This book is intended to be used in general courses in the Sixth Form, for students or academicians connected with psychology, sociology, social biology, education, health education, or interdisciplinary fields.

  • Recent Advances in the Pharmacology of Toxins

    Proceedings of the First International Pharmacological Meeting Stockholm, 22-25 August, 1961
    • 1st Edition
    • H. W. Raudonat
    • English
    Recent Advances in the Pharmacology of Toxins brings together the proceedings of the Second International Pharmacological Meeting of the International Union of Physiological Sciences, held in Prague, Czechoslovakia, on August 20-23, 1963. The meeting provided a forum for discussing advances in the understanding of the pharmacology of toxins and addressed topics ranging from antagonists of bradykinin to the mode of the spread of tetanus toxin in experimental animals. This volume is comprised of 28 chapters and begins with an analysis of the effects of toxins from microorganisms on mammalian cellular metabolism and structure, followed by a review of SRS-A, a slow-reacting substance of anaphylaxis, as a potential factor in the symptoms produced by venoms and toxins. Subsequent chapters explore the release of pharmacologically active lipids by enzymes contained in toxins; the structure and function of some enzymes in snake venoms, with reference to disulfide linkages; biochemistry and pharmacology of small-molecular compounds of cobra venom; and the role of ganglioside in the mode of action of tetanus toxin. This book will be of particular value to pharmacologists and physiologists.

  • Light and Plant Development

    • 1st Edition
    • H. Smith
    • English
    Light and Plant Development presents the Proceedings of the 22nd University of Nottingham Easter School in Agricultural Science. It discusses the spectral sensitivity of inhibition of flowering by light. It addresses the action spectrum for leaf enlargement and stem growth inhibition. Some of the topics covered in the book are the nature of the blue light photoreceptor in higher plants and fungi; re-examination of photochemical properties and absorption characteristics of phytochrome using high-molecular-weigh... preparations; and intermediates in the photoconversion of phytochrome. The high irradiance reaction is fully covered. The physiological evidence and localised responses, intracellular localisation and action of phytochrome are discussed in detail. The text describes in depth the immunological visualisation of phytochrome. The fractionation procedures and terminology are presented completely. A chapter is devoted to the photocontrol of enzyme levels. Another section focuses on the ribosomal RNA synthesis in developing leaves. The book can provide useful information to botanists, chemists, students, and researchers.

  • Photoreceptor Cells

    Methods in Neurosciences, Vol. 15
    • 1st Edition
    • Paul A. Hargrave
    • English
    Photoreceptor Cells, Volume 15 covers the advances in the study of photoreceptor cells. The book discusses biochemical, cell and structural biological, and molecular biological techniques needed for the study of photoreceptor cells. The text also describes the methods for observing the structure of photoreceptor cells and for studying their metabolism. The procedures for photoreceptor cell isolation are also considered. The book further tackles the preparation of proteins involved in rod cell metabolism, with particular emphasis on proteins of the visual transduction cascade. The text also encompasses the application of molecular biological techniques for the examination of molecular components of the visual system and their structure, distribution, and function. Neuroscientists, ophthalmologists, biochemists, and people involved in the study of photoreceptor cells will find the book invaluable.

  • Hazardous Waste Handbook for Health and Safety

    • 1st Edition
    • William F. Martin + 2 more
    • English
    Hazardous Waste Handbook for Health and Safety provides instructions and guidelines to supervisors responsible for occupational safety and health programs at hazardous waste sites. The manual presents the health and safety risks of hazardous waste sites; ways to implement and carry out hazardous waste site clean-up; preliminary basis for developing a specific health and safety program; and planning for and responding to emergencies involving hazardous materials. The book will be very useful to supervisors and safety engineers of hazardous waste sites.

  • Molecular Cell Pathology

    • 1st Edition
    • G. W. Richter + 1 more
    • English
    International Review of Experimental Pathology, Volume 32: Molecular Cell Pathology discusses the applications and practical value of in situ hybridization; the interactions between endothelial cells and the cells of the immune system; and the molecular biology of cytokine effects on vascular endothelial cells. The text also describes the interphase nucleolar organizer regions in cancer cells; the disease associations, molecular biology, and pathophysiology of antineutrophil cytoplasmic autoantibodies; and the mechanisms and roles of apoptosis in pathology. The molecular events in measles virus infection of the central nervous system are also considered. Pathologists, microbiologists, and immunologists will find the book useful.

  • Secondary Plant Products

    A Comprehensive Treatise
    • 1st Edition
    • Volume 7
    • Walter Stumpf + 1 more
    • English
    The Biochemistry of Plants: A Comprehensive Treatise, Volume 7: Secondary Plant Products focuses on the biochemistry of secondary compounds, including tissue culture and differentiation, complexes, and plant systematics. The selection first elaborates on the physiological roles of secondary natural products, tissue culture and the study of secondary natural products, and turnover and degradation of secondary natural products. Discussions focus on degradative reactions of nitrogenous and phenolic compounds, concept of turnover of secondary products, and plant-vertebrate interactions. The text then elaborates on secondary plant products and cell and tissue differentiation; compartmentation in natural product biosynthesis by multienzyme complexes; and secondary metabolites and plant systematics. The manuscript examines the stereochemical aspects of natural products biosynthesis, nonprotein amino acids, and amines. Topics include tryptamines, phenethylamines, and histamine, nonprotein amino acids as analogues and antimetabolites, chemistry and biogenesis, and nonprotein amino acids as indexes for chemotaxonomy. The book also tackles glycosylation and glycosidases; transmethylation and demethylation reactions in the metabolism of secondary plant products; and oxygenases and the metabolism of plant products. The selection is a vital reference for researchers interested in the biochemistry of secondary compounds.

  • Biological Husbandry

    A Scientific Approach to Organic Farming
    • 1st Edition
    • B. Stonehouse
    • English
    Biological Husbandry: A Scientific Approach to Organic Farming covers a proceeding of a symposium organized by International Institute of Biological Husbandry on August 26-30, 1980 at Wye College in London, United Kingdom. Said symposium aims to promote the scientific development of biological or organic agriculture. The text covers topics such as the assessment of conventional, biological, and integrated agriculture; soil use in temperate climates, organic matter cycles in tropical soils, and plant-microbial interactions; biological pest control, the importance of chemical agents and biotechnology in biological husbandry, and allelochemicals in the future of agriculture. The book is recommended for biologists and agriculturists who would like to know more about the studies in biological husbandry and its implications in the field.

  • Chemical Structure–Biological Activity Relationships: Quantitative Approaches

    Proceedings of the 3rd Congress of the Hungarian Pharmacological Society, Budapest, 1979
    • 1st Edition
    • F. Darvas
    • English
    Chemical Structure-Biological Activity Relationships: Quantitative Approaches, Volume III, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. This volume focuses on the methodological aspects of QSAR. It also aims to inform the reader about the QSAR research conducted in East-European countries. This volume contains 38 presentations organized into six sections. Several lecturers deal with ""real prediction"" cases, i.e. activity estimation prior to the synthesis of the compounds. A particularly abundant section is devoted to the question of how the receptor models can be built up by means of QSAR calculations. Other sections present mathematical models and algorithms which could be applied to improve further the effectiveness of QSAR calculations. As another unique feature, a separate section treats the quantitative aspects of peptide structure-activity relationships—a field seemingly backward despite its evident importance. Hydrophobicity and its influence on biological potency along with the relationship of steric properties and biological activity are also discussed.

  • Clostridium Difficile

    Its Role in Intestinal Disease
    • 1st Edition
    • Rial D. Rolfe
    • English
    Despite the tremendous progress made during the last few years in understanding the pathogenesis, epidemiology, diagnosis, and treatment of Clostridium difficile-associated intestinal disease, many extremely important and fundamental questions remain to be answered. The objectives of this book are to summarize the available information regarding Clostridium difficile and its role in intestinal disease and to serve as a basis for future investigations in this challenging area.Clostridium difficile: its role in Intestinal Disease. An excellent volume that should appeal not only to the devotee of C difficile but to all gastroenterologists and microbiologists, this will not languish on my library shelves like so many other books I have reviewed. It will be regularly thumbed. --R.H. George, consultant microbiologist, Children's Hospital, BirminghamClostridiu... difficile: Its Role in Intestinal disease. The book is well written and informative; it has a vast amount of information packed in it...this book would be a welcome addition to the researchers and clinicians interested in C difficile-associated intestinal diseases. --Edward Balish, University of Wisconsin Medical School

  • Antarctic Fish Biology

    Evolution in a Unique Environment
    • 1st Edition
    • Joseph T. Eastman
    • English
    This important volume provides an original synthesis and novel overview of Antarctic fish biology, detailing the evolution of these fish in some of the most unusual and extreme environments in the world. Focusing on one group of fish, the notothenoioids, which contain the majority of the current organismal diversity, this book describes a fauna that has evolved in isolation and experienced incredible adaptive radiation by acquiring numerous physiological specializations. Darwin's finches and African cichlids may be joined by Antarctic fishes as exemplars of adaptive radiation.The books' coverage is detailed and comprehensive, and the author clearly recognizes the fact that these fish are a component of a most interesting and biologically unique ecosystem and environment. Topics in Antarctic Fish Biology include past and present environments, fossil records, taxonomic composition of fauna, systematic relationships, diversification, and physiological adaptations.

  • Dale's Principle and Communication between Neurones

    Based on a Colloquium of the Neurochemical Group of the Biochemical Society, Held at Oxford University, July 1982
    • 1st Edition
    • Neville N. Osborne
    • English
    Dale's Principle and Communication Between Neurones is based on a colloquium of the Neurochemical Group of the Biochemical Society, held at Oxford University, July 1982. This book focuses on communication between neurones by means of chemical signals. The book contains an introductory chapter by V. P. Whittaker and nine further chapters on various aspects of the chemical communication processes between neurones. Topics covered include chemical communication between excitable cells; the neuroendocrine division of the nervous system; evidence for a neurone having the capacity to use two chemicals in the same process; and non-synaptic interneuronal communication. Each article is based on the excellent lectures given by the main authors and the discussion which ensued in the one-day colloquium held in Oxford. The final chapter is a specially invited contribution by Drs. Polak and Varndell, who agreed to produce an article on their new method of localising transmitter-like molecules at the electron-microscopic level.

  • Food and Agriculture in Global Perspective

    Discussions in the Committee of the Whole of the United Nations
    • 1st Edition
    • Toivo Miljan + 2 more
    • English
    Food and Agriculture in Global Perspective: Discussions in the Committee of the Whole of the United Nations presents the problem of food and agriculture in its total global international perspective from the point of view of the specialized agencies of the United Nations system and the States Members of the United Nations. The book discusses the problem of food and agriculture and its handling in the global perspective; groups the statements of the problem around international agency views and around the views of Member States; and presents the progress report of efforts by international agencies and by States. The text also describes the excerpts from the technical documents, and statements of Agency representatives and Member States in the seven specific issue areas found in the Agreed Conclusions of the Committee.

  • The Sounds of the Diseased Heart

    • 1st Edition
    • Aldo A. Luisada
    • English
    The Sounds of the Diseased Heart presents the comprehensive study on auscultation and phonocardiography. It discusses the description of the sounds of the normal heart. It addresses the dynamic interpretation of cardiovascular murmurs. Some of the topics covered in the book are the abnormal first heart sound; hypertrophy or dilatation of the left ventricular wall; dilatation of the pulmonary artery; moderate pulmonary stenosis; atrial septal defect; changes in the duration of ejection; ventricular type of triple rhythm; and differential diagnosis between the pulmonary component, the opening snap, and the third sound. The general interpretation of triple and quadruple rhythms is fully covered. The dynamic correlations of cardiovascular murmurs are discussed in detail. The text describes in depth the semilunar valve stenosis. The mitral valve and tricuspid valve defects are presented completely. A chapter is devoted to the esophageal phonocardiography. The book can provide useful information to cardiologists, doctors, students, and researchers.

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 4
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume IV covers the pharmaceutical phase of drug action, with emphasis on those aspects that are of importance in the design of optimally effective drug products. The book discusses biopharmaceutics as a basis for the design of drug products; the types and pharmacokinetics of peroral prolonged action dosage forms and parenteral prolonged action forms; and the design of topical drug products. The text also describes physical-chemical parameters which affect the bioavailability of topical drug products; the design of sunscreen preparations; as well as the clinical application of litholytic agents, which are preventive and curative drugs for nephrolithiasis. The design of biologically active nucleosides and of insecticidal chlorohydrocarbon derivatives is also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design will find the book invaluable.

  • Time in Animal Behaviour

    • 1st Edition
    • M. Richelle + 5 more
    • English
    A systematic presentation of the methods, facts and theoretical hypothesis concerning temporal regulation of behaviour and time estimation in animals is given.

  • Sectional Anatomy and Tomography of the Head

    • 1st Edition
    • Guy D. Potter
    • English
    Sectional Anatomy & Tomography of the Head focuses on the anatomical section of the head and its description. It discusses the slowly developing appearance of the head which includes the face, orbit, ears, sinuses, and base of the skull. It addresses the functions and structures of such parts. Some of the topics covered in the book are the anatomic section, radiographs, line drawings, and tomography of the coronal head, the lateral head, axial head, and oblique head. The frontal, lateral, axial, and oblique positions of the head are covered. A study of the axial features of the head is also presented. A chapter is devoted to the bone structures of the oblique area of the head. Another section focuses on the description of orbit, optic canal, nasal fossa, and temporal bone. The book can provide useful information to doctors, neurosurgeons, students, and researchers.

  • Human Atheroma

    With Particular Reference to Endocrine Aspects of Ætiology
    • 1st Edition
    • W. L. Ashton
    • English
    Human Atheroma (with Particular Reference to Endocrine Aspects of Aetiology) examines the endocrinological features of human atherosclerosis. This book is composed of 11 chapters that discuss the pathological sequelae and descriptive epidemiology of atheroma, commonly known as atherosclerosis. This book also addresses the mechanisms of arterial occlusion in the disease and the epidemiological observations on atherosclerosis. Some of the topics covered in the book are the clinical and pathological observations on atherosclerosis; common considerations in the association of endocrine with the disease; ovarian function and atheromatous disease; relationship between thyroid function and atherosclerosis; and clinical and epidemiological connections of atheroma and insulin. Other chapters deal with the associations between the development of diabetes mellitus and insulin, as well as the assay methods for insulin and insulin antagonists. An analysis of the hormonal disturbances in diabetic patients and their relatives is provided. The remaining chapters consider the insulin antagonism in diabetes mellitus and the measures suggested to decrease the number of atherosclerotic patients. The book can provide useful information to the cardiologists, doctors, students, and researchers.

  • Joll's Diseases of the Thyroid Gland

    • 2nd Edition
    • Francis F. Rundle
    • English
    Joll's Diseases of the Thyroid Gland, Second Edition provides information pertinent to the fundamental aspects of thyroid diseases. This book discusses the physiology structure, and development of the thyroid gland. Organized into 29 chapters, this edition begins with an overview of the function of the thyroid gland to trap and concentrate iodine, harness it in organic combination, and then to secrete it into the blood. This text then discusses the evolutionary scheme showing the development of thyroid gland as a special organ for the control of iodine metabolism. Other chapters consider the various types of thyroid diseases, including simple goiter, acute inflammations, Grave's disease, and granulomatous diseases of the thyroid. This book discusses as well the etiological or clinico-pathological basis of the classification of simple goiter. The final chapter deals with the post-operative complications of thyroidectomy and their treatment. This book is a valuable resource for physicians, surgeons, and clinical researchers.

  • Surtsey

    Evolution of Life on a Volcanic Island
    • 1st Edition
    • Sturla Fridriksson
    • English
    Surtsey: Evolution of Life on a Volcanic Island focuses on the origin of life in the island of Surtsey. The book first offers information on the Surtsey Research Society, conservation measures, and scientists that comprise the Surtsey research team. The text then focuses on the submarine eruptions off the coasts of Iceland, the flow of lava, and the formation and disappearance of islets. The book also describes the landscape that came about after the eruption. The tephra cones of the Surtur I and II craters, lava, coastal plains, and thermal areas are discussed. The text also underscores the ecological aspects of the eruption. The Icelandic biota and ecological studies on the island are discussed. The text also traces the origin of life in the island, including the dispersal of seeds by birds and “Mermaids purses.“ The text also underscores the origin of marine algae and marine fauna on the island. The book then emphasizes the presence of bacteria, molds, lichens, mosses, terrestrial animals, birds, and vascular plants in the island. The text also examines the outer Westman Islands. Topographical features, method of research, plant communities, and vegetation of the smaller islands are described. The book also notes the vegetation of Heimaey and the effects of insular eruptions on the southern coast of Iceland. The text is a good source of reference for readers wanting to study volcanic eruptions.

  • Cellular and Molecular Mechanisms of Inflammation

    Vascular Adhesion Molecules
    • 1st Edition
    • Charles G. Cochrane + 1 more
    • English
    Cellular and Molecular Mechanisms of Inflammation: Vascular Adhesion Molecules presents the study of the structure and function of constitutive and inducible cell surface structures, which contribute to the temporal and spatial patterns, and cellular selectivity of leukocyte-vessel wall interactions. The book addresses the rapidly expanding field of vascular adhesion molecules. Contributed articles discuss SELECTINS, a family of structurally related glycoproteins that contain lectin like domains that confer leukocyte-selective adhesive functions, which include ELAM-1 (Endothelial-Leukocy... Adhesion Molecule-1), GMP-140 (PADGEM, CD62), and LAM-1 (gp 90m e l, LEC-CAM-1, LECAM-1). Other adhesive molecules such as CD44 and members of the immunoglobulin family of cell surface glycoprotiens, including ICAM-1 (CD54), VCAM-1/ INCAM-110 and LP AM-1 are also considered. The text will be very useful to cytologists, molecular biologists, physiologists, and pharmacologists.

  • Neuropeptide Analogs, Conjugates, and Fragments

    Methods in Neurosciences, Vol. 13
    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 13: Neuropeptide Analogs, Conjugates, and Fragments covers the synthesis and characterization of peptide analogs, conjugates, and fragments, their use as ligands for receptors, and their role in the development and use of antisera. The book discusses techniques such as novel synthetic approaches; biotinylation; purification and characterization; radioligand techniques and assay development; use of agonists and antagonists; distinguishing receptor subtypes; conjugation to carrier proteins; antiidiotypic antibody development; and radiolabeling. Neuroscientists, biochemists, neurochemists, and pharmacologists will find the book useful.

  • Biochemistry of Characterised Neurons

    • 1st Edition
    • Neville N. Osborne
    • English
    Biochemistry of Characterised Neurons provides a report on the progress made in the analysis of the biology of specific neurons in the central nervous system. This book emphasizes the biochemical, morphological, and functional aspects of characterized neurons, including ways and sophisticated techniques of isolating them. This publication is divided into 11 chapters. The first chapter evaluates the relevance of working with single neurons. Chapters 2 to 6 discuss specific, characterized, invertebrate neurons containing one of the putative neurotransmitter substances. Chapter 7 deals with the biochemistry of a unique vertebrate (Torpedo) cholinergic system that enables pure cholinergic neuronal cell bodies and endings to be analyzed separately. The sensitive radiochemical procedures used to analyze transmitter substances and transmitter enzymes, and how they can be adapted to map the distribution of transmitters in individual neurons of Aplysia, are discussed in Chapter 8. Chapter 9 describes methods for the analysis of specific cells in the retina, while Chapters 10 and 11 focus on the analysis of proteins within defined neurons. This text is beneficial to biochemists and students interested in analyzing neurons.

  • A Synopsis of Children's Diseases

    • 1st Edition
    • John Rendle-Short
    • English
    A Synopsis of Children's Diseases is a reference of common, rare, or very rare diseases in children. The book describes the characteristics of a healthy child including the requirements for his management and proper nutrition. Examination of the child through routine physical examination or certain special examinations, such as blood tests, marrow smear, cerebrospinal fluid tests, or urine test will indicate if the child is sick. The text describes diagnosis and treatment of infectious diseases (measles, mumps), of nutrition (marasmus syndrome, infantile scurvy), of the respiratory system (tonsils, sinuses), and the alimentary system (diarrhea, intestinal obstruction). The book also describes diseases affecting the cardiovascular system, the nervous system, psychological disorders, the genitor-urinary system, the blood, and the lymph nodes. Inborn errors of metabolism include Gaucher's disease, cerebromacular degeneration, generalized xanthomatosis, diabetes mellitus, and Von Gierke's disease. The text discusses allergies, venereal disease, and accidents that can occur in childhood such as burns, scalds, lead or iron poisoning. This book is suitable for pediatricians, general practitioners, medical students, and parents who are interested in obtaining information about childhood diseases.

  • The Constant Catastrophe

    Malnutrition, Famines and Drought
    • 1st Edition
    • Rolando V. Garcia + 1 more
    • English
    The Constant Catastrophe: Malnutrition, Famines, and Drought deals with the 1972 drought, and emphasizes the underlying social conditions that are related to its effects. The book examines the relationship of drought as a meteorological event and the famine that results as a social event. The effects of natural catastrophes become transformed by social structures and political processes in many countries of the world, more than which can be attributable to the physical cause itself. A striking parallelism that emerges in the study is that climatological analysis implies reference to large scale space and time processes. Famine also occurs as anomalies within large-scale processes in society—famine changes nutritional levels in communities. The text proposes a theoretical framework for a methodologically-ade... diagnostic tool that can be used in studying the "factual events" in previous cases of major disasters due to climactic factors. Case studies include those that happened in the Sahel, Ethiopia, India, China, the United Kingdom, and Brazil. Among several recommendations, one which the book proposes in the management of the effects of drought, is to adopt an approach similar to that of the Red Cross. The book is suitable for economists, environmentalists, ecologists, and policy makers involved in crisis management, food production, and rural development.

  • Introduction to Animal Physiology and Physiological Genetics

    International Series of Monographs in Pure and Applied Biology
    • 1st Edition
    • E. M. Pantelouris
    • G. A. Kerkut
    • English
    Introduction to Animal Physiology and Physiological Genetics, deals with topics on physiological measurement, comparisons, and analysis of the role of genotypes. This book emphasizes two aspects — the changes of physiological patterns in the course of development and the wide variation that can be found within a species. The text discusses the response mechanisms of living organisms from nerve impulses, chemical sense, muscle reaction, and includes some studies made on brain function. The effects of nutrition and energy such as the intake of food, water, oxygen, and the calculation of basic metabolic rates are explained. The book then discusses the role of the internal environment and that of the interstitial body fluid in the higher animals. The discussion covers blood circulation, cardiac cycle, and a special section on the function of the heartbeat in the spider Limulus showing that stimulation of the abdominal ganglia increases the heartbeats. The text also considers significant concepts of physiological genetics, and then explains asexual and sexual reproduction, the sex hormones of invertebrates, and the use of stimulants for animal production. The physiological differences between species are examined, but more particularly on the reservoir of genetic diversity, where differences abound between families and offspring. One research made in molecular biology concludes that genes are responsible for regulating the amino acid sequence of proteins. Molecular biologists, general biologists, zoologists, and microbiologists will find the articles in this collection invaluable.

  • Polysaccharides in Food

    • 1st Edition
    • J.M.V. Blanshard + 1 more
    • English
    Polysaccharides in Food is a collection of papers that discusses concepts and advancements related to polysaccharides found in food products. The book is divided into five parts; Part I deals with topics such as the polysaccharides of the plant cell during growth; polysaccharide structure in solutions and gels; and the solvent interactions and solution behavior of carbohydrates. Part II covers the relationship of polysaccharides and enzymes and includes topics such as the enzymic degradation of starches; the hemicellulase group of enzymes; and pectic enzymes. Part III discusses the structure and physiochemical aspects of starch, as well as its use in food. Part IV tackles polysaccharides in food product development, and Part V deals with kinds of polysaccharides and the legislations concerning them. Part VI covers the importance of polysaccharides as the population's energy source as well as its health benefits. The text is recommended for food technicians, nutritionists, and organic chemists who would like to know more about the importance of polysaccharides in food and its future.

  • Neurotransmitters, Receptors

    Proceedings of the 8th International Congress of Pharmacology, Tokyo, 1981
    • 1st Edition
    • H. Yoshida + 2 more
    • English
    Advances in Pharmacology and Therapeutics II, Volume 2: Neurotransmitters-Re... is the second of a six-volume compilation of the scientific papers of invited speakers of the Eighth International Congress of Pharmacology. Organized into seven parts, this book begins with an invited lecture on the kinetic analysis of the neuronal and extraneuronal uptake and metabolism of catecholamines. Subsequent parts discuss the regulation of receptor-mediated events; presynaptic receptors in the peripheral and central nervous system; neurotransmitters; and receptor antibodies. The isolated nervous systems in the research of neurotransmission and trophic interactions between nerve and muscle are also discussed.

  • Ultrastructural Pathology of the Cell and Matrix

    A Text and Atlas of Physiological and Pathological Alterations in the Fine Structure of Cellular and Extracellular Components
    • 3rd Edition
    • Feroze N. Ghadially
    • English
    Ultrastructural Pathology of the Cell and Matrix: Third Edition Volume I present a comprehensive examination of the intracellular lesion. It discusses the analysis of pathological tissues using electron microscope. It addresses the experimental procedures made on the cellular level. Some of the topics covered in the book are the physiological analysis of the nucleus; nuclear matrix, interchromatin, and perichromatin granules; structure and function of centrioles; characteristics of mitochondria; Golgi complex in cell differentiation and neoplasia; and degranulation of rough endoplasmic reticulum. The intracytoplasmic and intranuclear annulate lamellae are fully covered. An in-depth account of the classification, history, and nomenclature of lysosomes are provided. The morphology and normal variations of melanosomes and anchoring fibrils are completely presented. A chapter is devoted to the endocytotic structures and cell processes. Another section focuses on the classification and nomenclature of fibrous components. The book can provide useful information to cytologists, scientists, students, and researchers.

  • Parasitic Protozoa

    Volume 9
    • 2nd Edition
    • Julius P. Kreier
    • English
    Updated and much expanded, the Second Edition of Parasitic Protozoa is designed to be useful to physicians, veterinarians, and research scientists concerned with diseases caused by protozoa in man, and in domestic and wild animals including fish, mollusks and insects, as well as the more commonly considered vertebrate animals. Each section contains information on disease pathogens, treatment, diagnosis, and epidemiology of the diseases caused by the various protozoans. The book is not limited to these medically-oriented subjects, but treats taxonomy, morphology, and metabolism of the organisms in such a way as to be of interest to scientists and graduate students working in the field of protozoology. The entire edition, published in ten volumes, is arranged so that subjects of common interest occupy individual volumes.

  • Essays in Toxicology

    Volume 7
    • 1st Edition
    • Wayland J. Hayes
    • English
    Essays in Toxicology, Volume 7 presents essays on toxicology and related topics. The book presents essays on the effects of toxicants on reproductive performance; an overall view of carcinogenesis from an epidemiological viewpoint and the potentialities and limitations of the epidemiological method in cancer control; and the activity of cytochrome P450 and mixed-function oxidase in target and nontarget organisms. The text also includes essays on the toxicity of hexachlorophene and the use of hexachlorophene as an antibacterial agent; the methodology, dose measurement, and respiratory function assessment in respiratory toxicology; as well as behavioral toxicology, with focus on early warning and worker safety and health. Pharmacologists, biochemists, pathologists, neurophysiologists, epidemiologists, and toxicologists will find the book invaluable.

  • Developmental and Cellular Skeletal Biology

    • 1st Edition
    • Brian K. Hall
    • English
    Developmental and Cellular Skeletal Biology reviews the development, growth, and cell biology of the skeleton. The monograph provides a comprehensive overview of the aspects of skeletal biology, focusing mainly on the cellular level. It covers topics on the types of skeletal tissues, its evolution, and origin; location of the skeleton within the embryo; initiation of centers of skeletogenesis; and the initiation of skeletal growth. The book will be of great use to physiologists, cell biologists, hematologists, pathologists, orthopedic surgeons, and others whose professions are concerned with the study of the skeletal system.

  • Methods in Behavioral Pharmacology

    • 1st Edition
    • Volume 10
    • F. van Haaren
    • English
    Methods in Behavioral Pharmacology is unique in offering a complete description and critical evaluation of most, if not all, methods available to study the effects of drugs on behavior. It stands apart in that it is not limited to the analysis of a particular class of pharmacological agents in a limited number of paradigms. Methods in Behavioral Pharmacology covers all paradigms without reference to specific pharmacological compounds.The book provides a comprehensive overview of the methodology used to study the behavioral effects of legal and illegal drugs. It also provides an in-depth presentation of dependent variables, their quantification and a critical evaluation of their advantages and disadvantages. An excellent work, contributed to by well-known experts in the different fields of behavioral pharmacology.

  • The Clinical Significance of the Essential Biological Metals

    • 1st Edition
    • I. J. T. Davies
    • English
    The Clinical Significance of the Essential Biological Metals covers the six trace minerals necessary for human survival,namely zinc, copper, manganese, molybdenum, chromium, and cobalt. This book contains seven chapters that specifically discuss the effects of these minerals for enzyme function, protein synthesis, and their nutritional significance in veterinary and agricultural practice. Some of the topics covered in the book are the importance of interactions between the essential biological metals; importance of fertilizers; analysis of water supply, soil mineral content, and cancer mortality; influence of drinking water on atherosclerosis; non-essential but biologically important metals; and absorption and availability of zinc. Other chapters deal with the factors influencing absorption of zinc, the effects of copper on zinc availability, and the form and absorption of copper in the diet. A chapter is devoted to the role of lymphatics in copper absorption. Another chapter focuses on the distribution, absorption, and transport of manganese in the blood. The book can provide useful information to doctors, biochemists, nutritionists, students, and researchers.

  • Schering Workshop on Steroid Hormone 'Receptors', Berlin, December 7 to 9, 1970

    Advances in the Biosciences
    • 1st Edition
    • Gerhard Raspé
    • English
    Advances in the Biosciences 7: Schering Workshop on Steroid Hormone ""Receptors,"" Berlin, December 7 to 9, 1970 is a collection of papers presented at the Schering Workshop on Steroid Hormone ""Receptors,"" held in Berlin, Germany, on December 7-9, 1970. Contributors review research findings concerning steroid hormone receptors and cover topics organized around receptors of estrogen, androgen, progesterone, aldosterone, and corticosteroids. This book is comprised of 20 chapters and begins by analyzing the concentration of the estrogen binding protein in the rat uterus in three stages of uterine development, followed by a discussion on estradiol binding in mammalian tissues. The next section explores androgen receptors and includes chapters dealing with the specific binding of steroid-receptor complexes to DNA as well as the effects of androgen receptors on rat and human prostate. Subsequent chapters discuss the action of progesterone, aldosterone, and corticosteroid receptors. This monograph will be of interest to biochemists, biologists, and physiologists.

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