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Biofabrication
Micro- and Nano-fabrication, Printing, Patterning and Assemblies
- 1st Edition - March 18, 2013
- Editors: Gabor Forgacs, Wei Sun
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 2 8 2 5 4 - 3
- Hardback ISBN:9 7 8 - 1 - 4 5 5 7 - 2 8 5 2 - 7
- eBook ISBN:9 7 8 - 1 - 4 5 5 7 - 3 0 0 4 - 9
Biofabrication is a practical guide to the novel, inherently cross-disciplinary scientific field that focuses on biomanufacturing processes and a related range of emerging… Read more
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Request a sales quoteBiofabrication is a practical guide to the novel, inherently cross-disciplinary scientific field that focuses on biomanufacturing processes and a related range of emerging technologies. These processes and technologies ultimately further the development of products that may involve living (cells and/or tissues) and nonliving (bio-supportive proteins, scaffolds) components. The book introduces readers to cell printing, patterning, assembling, 3D scaffold fabrication, cell/tissue-on-chips as a coherent micro-/nano-fabrication toolkit. Real-world examples illustrate how to apply biofabrication techniques in areas such as regenerative medicine, pharmaceuticals and tissue engineering.
In addition to being a vital reference for scientists, engineers and technicians seeking to apply biofabrication techniques, this book also provides an insight into future developments in the field, and potential new applications.
- Discover the multi-disciplinary toolkit provided by biofabrication and apply it to develop new products, techniques and therapies
- Covers a range of important emerging technologies in a coherent manner: cell printing, patterning, assembling, 3D scaffold fabrication, cell/tissue-on-chips...
- Readers develop the ability to apply biofabrication technologies through practical examples
R&D teams, researchers and scientists in the fields of Bioengineering / Biomaterials / Biofabrication / Biomedical Engineering / Tissue Engineering; Regenerative Medicine, Biotechnology, Pharmaceuticals, Mechanical Engineering.
Engineers and Industrial scientists at pharmaceutical companies, biotech companies, medical device companies.
Biotechnologists and Process E
Preface
List of Contributors
Chapter 1. In Vitro Biofabrication of Tissues and Organs
Introduction
1.1 Problems with scaffold-based tissue engineering
1.2 “Scaffold-free” tissue engineering
1.3 Aggregation/spheroid-based approaches
Conclusion
References
Chapter 2. Biomaterials for Biofabrication of 3D Tissue Scaffolds
Introduction
2.1 Materials for 3D tissue scaffolds
2.2 Fabrication methods for 3D tissue scaffolds
2.3 Application of 3D tissue scaffolds
2.4 Future perspectives of biomaterials for 3D scaffolds
Conclusion
Acknowledgment
References
Chapter 3. Projection Printing of Three-Dimensional Tissue Scaffolds with Tunable Poisson’s Ratio
Introduction
3.1 Digital micromirror-assisted projection printing stereolithography
3.2 Negative Poisson’s ratio biomaterials
3.3 Hybrid Poisson’s ratio biomaterial
3.4 Zero Poisson’s ratio biomaterials
Conclusion
References
Chapter 4. Fabrication of Microscale Hydrogels for Tissue Engineering Applications
Introduction
4.1 Technologies for fabrication of microengineered hydrogels
4.2 Tissue engineering applications
Conclusion
Acknowledgments
References
Chapter 5. Polymeric Membranes for the Biofabrication of Tissues and Organs
Introduction
5.1 Properties of polymeric membranes
5.2 Membranes for tissue engineering
5.3 Hollow fiber polymeric membranes for cell and tissue perfusion
5.4 Membrane bioreactors for tissue constructs
5.5 Future perspectives
References
Chapter 6. Laser-Assisted Bioprinting for Tissue Engineering
Introduction
6.1 LAB’s terms of reference
6.2 LAB parameters for cell printing
6.3 High-resolution/high-throughput trade-offs
6.4 Three-dimensional printing: the layer-by-layer approach
6.5 Applications
Conclusion
Acknowledgments
References
Further Reading
Chapter 7. The Modular Approach
Introduction
7.1 Materials used to fabricate the modular building blocks
7.2 Intrinsically vascularized tissue constructs
7.3 Building tissue constructs by assembling building blocks
7.4 Modular tissue engineering combined with microfluidics
Conclusion
References
Chapter 8. Formation of Multicellular Microtissues and Applications in Biofabrication
Introduction
8.1 Materials and methods
8.2 Results
8.3 Discussion
8.4 Future considerations
References
Chapter 9. A Digital Microfabrication-Based System for the Fabrication of Cancerous Tissue Models
Introduction
9.1 Digital micro-mirroring microfabrication system
9.2 Multinozzle biologics deposition system
9.3 Methods and materials
9.4 Results
Conclusion
References
Chapter 10. Breast Reconstruction Using Biofabrication-Based Tissue Engineering Strategies
Introduction
10.1 Anatomy of the breast
10.2 Current methods of breast reconstruction
10.3 Biofabrication-based tissue engineering strategy
Conclusion
References
Chapter 11. Fabrication of Artificial Bacteria for Targeted Drug Delivery
Introduction
11.1 Drug delivery
11.2 Bioinspired locomotion and microswimming
11.3 Materials and methods
Conclusion
Acknowledgment
References
Chapter 12. Biofabricating the Bio-Device Interface Using Biological Materials and Mechanisms
Introduction
12.1 Complementarity of biofabrication and microfabrication
12.2 Biofabrication methods
12.3 Biofabrication of a multifunctional matrix
12.4 Postfabrication biofunctionalization of devices
12.5 Test device
12.6 Electroaddressing a biosensing enzyme
12.7 Creation of a spatially segregated bacterial biofilm
Conclusion
Acknowledgment
References
Index
- No. of pages: 288
- Language: English
- Edition: 1
- Published: March 18, 2013
- Imprint: William Andrew
- Paperback ISBN: 9780323282543
- Hardback ISBN: 9781455728527
- eBook ISBN: 9781455730049
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