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Books in Life sciences

  • Mitophagy in Health and Disease

    Mechanisms, Health Implications, and Therapeutic Opportunities
    • 1st Edition
    • November 28, 2024
    • John J. Lemasters
    • English
    Mitophagy in Health and Disease: Mechanisms, Health Implications, and Therapeutic Opportunities is a complete reference to this key cellular process involved in homeostasis. The book addresses the machinery and mechanisms of mitophagy, including an overview of mito-biogenesis and dynamics and specific types of mitophagy. Other sections cover mitophagy across the human lifespan, from development to aging, discussing the interplay between inflammation and several conditions. The final part covers therapeutic opportunities presented by targeting mitophagy, including inducers and inhibitors, targeting strategies, and studies specific to cardioprotection and neurodegenerative diseases prevention.This is the ideal reference for cellular and molecular biologists needing a consistent and thorough overview of the subject, as well as research physicians in areas where mitochondria play a key role.

  • Deep Learning in Genetics and Genomics

    Volume 1: Foundations and Introductory Applications
    • 1st Edition
    • November 28, 2024
    • Khalid Raza
    • English
    Deep Learning in Genetics and Genomics vol. 1, Foundations and Applications, the intersection of deep learning and genetics opens up new avenues for advancing our understanding of the genetic code, gene regulation, and the broader genomics landscape. The book not only covers the most up-to-date advancements in the field of deep learning in genetics and genomics, but also a wide spectrum of (sub) topics including medical and clinical genetics, predictive medicine, transcriptomic, and gene expression studies. In 21 chapters Deep Learning in Genetics and Genomics vol. 1, Foundations and Applications describes how AI and DL have become increasingly useful in genetics and genomics research where both play a crucial role by accelerating research, improving the understanding of the human genome, and enabling personalized healthcare. From the fundamentals concepts and practical applications of deep learning algorithms to a wide range of challenging problems from genetics and genomics, Deep Learning in Genetics and Genomics vol. 1, Foundations and Applications creates a better knowledge of the biological and genetics mechanisms behind disease illnesses and improves the forecasting abilities using the different methodologies described. This title offers a unique resource for wider, deeper, and in-depth coverage of recent advancement in deep learning-based approaches in genetics and genomics, helping researchers process and interpret vast amounts of genetic data, identify patterns, and make discoveries that would be challenging or impossible using traditional methods.

  • Deep Learning in Genetics and Genomics

    Volume 2: Advanced Applications
    • 1st Edition
    • November 28, 2024
    • Khalid Raza
    • English
    Deep Learning in Genetics and Genomics: Vol. 2 (Advanced Applications) delves into the Deep Learning methods and their applications in various fields of studies, including genetics and genomics, bioinformatics, health informatics and medical informatics generating the momentum of today's developments in the field. In 25 chapters this title covers advanced applications in the field which includes deep learning in predictive medicines), analysis of genetic and clinical features, transcriptomics and gene expression patterns analysis, clinical decision support in genetic diagnostics, deep learning in personalised genomics and gene editing, and understanding genetic discoveries through Explainable AI. Further, it also covers various deep learning-based case studies, making this book a unique resource for wider, deeper, and in-depth coverage of recent advancement in deep learning based approaches. This volume is not only a valuable resource for health educators, clinicians, and healthcare professionals but also to graduate students of genetics, genomics, biology, biostatistics, biomedical sciences, bioinformatics, and interdisciplinary sciences.

  • Ecology of Marine Fish

    • 1st Edition
    • November 28, 2024
    • Henrique Cabral + 3 more
    • English
    Ecology of Marine Fish offers updated reviews of the current knowledge on the ecology of marine fish. This book is an all-inclusive reference on the diversity of marine fish, their behaviors, their role in marine food webs, as well as the human and environmental impacts on marine fish, such as pollutants and climate change. It takes a historical approach to discussing spatial and temporal patterns of fish populations and introduces the changing patterns of the present. Each chapter provides an in-depth review of the science behind marine fish populations and the methodological tools to study them.This book is an excellent resource for anyone in the fisheries sector, including scientists and researchers, fisheries managers, marine resource managers, marine biologists, fish farmers, marine ecologists, policy makers, leaders and regulators, operations researchers, as well as students and faculty studying marine fish ecology.

  • Electrocardiography of Channelopathies

    A Primer for the Clinical Cardiologist
    • 1st Edition
    • November 27, 2024
    • Manlio F. Márquez-Murillo
    • English
    Electrocardiography of Channelopathies: A Primer for the Clinical Cardiologist introduces readers to the inherited arrhythmia syndromes that are a leading cause of sudden cardiac death. As the ECG is the cornerstone of identifying inherited arrhythmia syndromes, this cutting-edge book is a critical resource to guide cardiologists in using the technology for optimum diagnosis and treatment of their patients. It clearly delineates the differences between each syndrome to improve accuracy and health outcomes. Its easy portability belies a vast knowledge base for use by clinicians in the moment as well as by researchers in the laboratory.This book illuminates diseases such as Short and Long QT Syndromes, Andersen-Tawil Syndrome, Brugada Syndrome, Polymorphic Ventricular Tachycardia, and Early Repolarization syndrome. Electrocardiography of Channelopathies: A Primer for the Clinical Cardiologist will no doubt become a go-to reference for experienced clinicians seeking confirmation of their diagnoses, as well as those newer to the field seeking guidance in ECG interpretation.

  • Digital Pathology

    Implementation in Clinical Practice with AI applications
    • 1st Edition
    • November 27, 2024
    • Meera Hameed + 1 more
    • English
    Digital Pathology: Implementation in Clinical Practice with AI Applications covers digital pathology applications in a clinical pathology laboratory setting, providing guidance and various tools for practical implementation. This comprehensive and detailed description of nuts and bolts of digital pathology implementation is unique and comes from the experience of high throughput scanning from a large surgical pathology laboratory. This is a valuable reference to prepare the end users not only about thoughtful launch of digital pathology but also to prepare for the future use of AI mediated decision support tools as the field advances.This book covers the entire range of this topic and can be used as a practical reference for individuals that wish to be part of the evolution of diagnostic pathology. Sections include pre-analytic, analytic, and post-analytic processes, encompassing hardware, software, space, staffing, quality control, laboratory information system applications, clinical validation, use cases and future applications, including computer assisted diagnosis and decision support tools.

  • T Cell Metabolism and Cancer Immunotherapy

    • 1st Edition
    • November 27, 2024
    • Jianxun Song
    • English
    T Cell Metabolism and Cancer Immunotherapy delves into the intricate regulation of T-cell immunity and tolerance. As research advances in cell-based therapies, the potential of engineered immune cells to treat cancers and other diseases is becoming increasingly evident due to their powerful capabilities. Additionally, the book offers valuable insights into developing and optimizing strategies for bacterium-based immunotherapies. Despite great advancement in immunotherapy such as adoptive T cell transfer-based regimen, the clinical outcomes remain less satisfactory due to a variety of factors that lessen its therapeutic efficacy. By determining the role and importance of T cell metabolism in the regulation of T lymphocytes that are related to the development and managements of aberrant immunity, T Cell Metabolism and Cancer Immunotherapy designs and develops novel and more effective strategies for improving regimens for patients with aberrant immunity. Within ten chapters the content not only reveals targets of T cell metabolism as critical determinants of immune regulation, but also uncovers unique therapeutic opportunities to improve immunotherapy through targeting T cell metabolism. This fills a significant gap in the knowledge of scientists working in the field of onco-immunology/immu... and students learning about T cells, metabolism, immunomodulation, and immunotherapy.

  • Time-Resolved Methods in Structural Biology

    • 1st Edition
    • Volume 709
    • November 27, 2024
    • English
    Time-Resolved Methods in Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 40
    • November 27, 2024
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 40 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Bacterial Enzymes as Targets for Drug Discovery

    Meeting the Challenges of Antibiotic Resistance
    • 1st Edition
    • November 27, 2024
    • Punit Kaur + 1 more
    • English
    Bacterial Enzymes as Targets for Drug Discovery: Meeting the Challenges of Antibiotic Resistance addresses the gap between medical microbiology, structural biology, and genomic science in the development of new antibacterial drug development. This book consolidates detailed profiling of bacterial target enzyme families for the drug discovery process and methodologies for use and validation of the potential drug targets. The contents cover the foundations of the antibiotic drug discovery process and focus on bacterial enzymes as drug targets, building across these disciplines to provide a comprehensive resource in bacterial structural biology and genomics. This is the ideal reference for antibiotic drug discovery researchers in the pharma industry and academia. Biochemists, microbiologists, and medicinal chemists will also benefit from this books’ content.

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