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International Review of Cell and Molecular Biology

1st Edition - August 2, 2016

Editors: Lorenzo Galluzzi, Kwang W. Jeon

Hardback ISBN:

9 7 8 - 0 - 1 2 - 8 0 4 8 0 5 - 4

eBook ISBN:

9 7 8 - 0 - 1 2 - 8 0 5 2 2 1 - 1

International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. The series has a worldwide readership,… Read more

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International Review of Cell and Molecular Biology

presents comprehensive reviews and current advances in cell and molecular biology.

The series has a worldwide readership, maintaining its high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists.

Contributors
Chapter One: Compartmentalization and Regulation of Sulfate Assimilation Pathways in Plants
- Abstract
- 1. Introduction
- 2. Sulfate Transport Systems
- 3. Sulfate Assimilation
- 4. Conclusions and Future Perspectives
- Acknowledgments
Chapter Two: Insight Into the Role of Long Noncoding RNA in Cancer Development and Progression
- Abstract
- Abbreviations
- 1. Introduction
- 2. Roles of lncRNA During Cancer Development
- 3. Cancer Cell Survival
- 4. LncRNA in Cancer Stem Cell
- 5. Insight of Novel lncRNA Roles in Cancer
- 6. Diagnostic and Prognostic Value of lncRNAs
- 7. Concluding Remarks
- Acknowledgment
Chapter Three: Endogenous Mechanisms of Cardiac Regeneration
- Abstract
- 1. Introduction
- 2. Endogenous Cellular Sources for Cardiac Regeneration
- 3. Molecular Mechanisms Limiting Cardiac Regeneration
- 4. Molecular Mechanisms Stimulating Cardiac Regeneration
- 5. Nonmyocyte Regulation of Cardiac Regeneration
- 6. Summary and Prospects
- Acknowledgments
Chapter Four: NF-κB signaling as a driver of ageing
- Abstract
- Abbreviations
- 1. Introduction
- 2. NF-κB Signaling Pathway
- 3. NF-κB Activation in Ageing
- 4. Monitoring NF-κB Activity During Ageing
- 5. NF-κB Signaling in Ageing
- 6. NF-κB and Cancer
- 7. NF-κB as a Biomarker of Ageing
- 8. Rejuvenation Approaches Based on NF-κB Inhibition
- 9. Conclusions
- Acknowledgments
Chapter Five: Metabolic and Signaling Functions of Cancer Cell-Derived Extracellular Vesicles
- Abstract
- 1. Introduction
- 2. Cellular Metabolism and Exosomes
- 3. Future Perspectives and Directions
Chapter Six: Mutually Supportive Mechanisms of Inflammation and Vascular Remodeling
- Abstract
- Abbreviations
- 1. Introduction
- 2. Inflammation Promotes Angiogenesis and Vascular Remodeling
- 3. Inflammatory Angiogenesis and Disease Progression
- 4. Postischemic Revascularization
- 5. Angiogenesis Supports Chronic Inflammation
- 6. Conclusions
- Acknowledgments
Chapter Seven: Pharmacological Actions of Glucagon-Like Peptide-1, Gastric Inhibitory Polypeptide, and Glucagon
- Abstract
- 1. Introduction
- 2. Glucagon-Like Peptide-1
- 3. GIP
- 4. Glucagon
- Acknowledgments
Chapter Eight: Interferon Beta: From Molecular Level to Therapeutic Effects
- Abstract
- 1. Introduction
- 2. Three-Dimensional Structure of IFNβ
- 3. Dynamic Conformation of IFNβ
- 4. IFNβ-Signaling Pathway
- 5. IFNβ Activities
- 6. Therapeutic Effects of IFNβ in Different Diseases
- 7. Immunogenicity, Major Issue Related to Some Types of IFNβ therapy
- 8. How to Overcome Immunogenicity of IFNβ
- 9. Conclusions
- Acknowledgments
Index

Lorenzo Galluzzi

Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza”. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology. Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals: OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.

Affiliations and expertise

Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USA

Kwang W. Jeon

Kwang Jeon received his Ph.D. in cell physiology at King’s College, University of London, UK, in 1964 and taught at SUNY Buffalo and University of Tennessee. His research was concerned with the biogenesis and function of cell components in two major areas: Integration of intracellular symbionts into host cells leading to the acquisition of new cell components and cell variation; Membrane-protein recycling during endo- and exocytosis.

Affiliations and expertise

University of Tennessee, Knoxville, TN, USA