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Elsevier

Books in Life sciences

  • Darwin’s Pangenesis and Its Rediscovery Part B

    • 1st Edition
    • Volume 102
    • Dhavendra Kumar
    • English
    Darwin’s Pangenesis and its Rediscovery Part B explores Darwin's Pangenesis, an expanded cell theory and unified theory of heredity and variation from over 150 years ago that strengthened his theory of evolution and explained many phenomena of life. Now, new discoveries on circulating DNA, mobile RNAs, prions and extracellular vesicles are providing striking evidence for the chemical existence of Darwin’s imaginary gemmules. In addition, new evidence for the inheritance of acquired characters, graft hybridization, and many other phenomena that Pangenesis supposedly explains are progressing, and are hence explored in this comprehensive volume. Specific chapters in this new volume include Darwin and Mendel: The Historical Connection, Darwin’s Pangenesis and Graft Hybridization, Darwin’s Pangenesis and Medical Genetics, Darwin’s Pangenesis and Certain Anomalous Phenomena, and Natural Selection and Pangenesis: The Darwinian Synthesis.

  • Polyphenols in Plants

    Isolation, Purification and Extract Preparation
    • 2nd Edition
    • Ronald Ross Watson
    • English
    Polyphenols in Plants: Isolation, Purification and Extract Preparation, 2nd edition, provides a detailed insight into polyphenols that occur naturally in plants and how they can be affected during growth and development, then effectively removed and optimized for various applications in food production. Historically, plants have been the major sources for drugs and health promotion. While there are a small number of nutrients contained, the growing focus is on the very diverse, complex ring structures: polyphenols that are not nutritious. In order to study or use them in patient treatment, the polyphenols need to be isolated, identified, and purified for application and study. This book brings together experts in the field who share their ongoing examination of isolation and purification of polyphenols as well as determination of their structures and composition. Polyphenols in Plants covers a range of new topics including polyphenols in vegetable waste and agricultural byproducts, extraction methods and characterization of polyphenols, and isolation techniques in the development of new compounds and their use in cancer therapy. This book will be useful to plant scientists and dietary supplement producers, as well as scientists in the food industry and alternative medicine who are interested in the specific health benefits of various dietary extracts and other polyphenol resources.

  • Postharvest Disinfection of Fruits and Vegetables

    • 1st Edition
    • Mohammed Wasim Siddiqui
    • English
    Postharvest Disinfection of Fruits and Vegetables describes available technologies to reduce microbial infection for maintaining postharvest quality and safety. The book analyzes alternative and traditional methodologies and points out the significant advantages and limitations of each technique, thus facilitating both cost and time savings. This reference is for anyone in the fresh produce industry who is involved in postharvest handling and management. It discusses, in detail, the latest disinfection approaches, low-cost treatment strategies, management and protocols to control fresh produce qualities, diseases and insect infestation.

  • The Teeth of Mammalian Vertebrates

    • 1st Edition
    • Barry Berkovitz + 1 more
    • English
    "The Teeth of Mammalian Vertebrates is an important reference for researchers in dentistry, comparative morphology, anthropology, and vertebrate palaeontology, and those with an interest in exploring and understanding diversity. The book provides a comprehensive and informed analysis of mammalian dentitions and highlights the importance of teeth as drivers and mirrors of evolution and diversity." - Journal of Anatomy The Teeth of Mammalian Vertebrates presents a comprehensive survey of mammalian dentitions that is based on material gathered from museums and research workers from around the world. The teeth are major factors in the success of mammals, and knowledge of tooth form and function is essential in mammalian biology. Illustrated with high-quality color photographs of skulls and dentitions, together with X-rays, CT images and histology, this book reveals the tremendous variety of tooth form and structure in mammals. Written by two internationally-reco... experts in dental anatomy, the book provides an up-to-date account of how teeth are adapted to acquiring and processing food. With its companion volume, this book provides a complete survey of the teeth of vertebrates. It is the ideal resource for students and researchers in zoology, biology, anthropology, archaeology and dentistry.

  • Obesity

    Oxidative Stress and Dietary Antioxidants
    • 1st Edition
    • Amelia Marti del Moral + 1 more
    • English
    Obesity: Oxidative Stress and Dietary Antioxidants cover the science of oxidative stress in obesity and associated conditions, including metabolic syndrome, bariatric surgery, and the potentially therapeutic usage of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are not described in isolation, but in concert with other processes, such as apoptosis, cell signaling and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is but a single component. The book is designed for nutritionists, dietitians, food scientists, physicians and clinical workers, health care workers and research scientists.

  • Lentils

    Potential Resources for Enhancing Genetic Gains
    • 1st Edition
    • Mohar Singh
    • English
    Lentils: Potential Resources for Enhancing Genetic Gains describes the evolutionary aspects and agronomic potential of this important pulse with emphasis placed on wide hybridization, including molecular aspects and future breeding strategies. The existing variability among cultivated germplasm has been exploited to reach a desirable level of productivity. However, to attain further breakthroughs in increasing yield and improving stability in future cultivars, new sources of genes/alleles need to be identified and incorporated into cultivated varieties. This book provides specific use information, including wild lentil germplasm utilization, thus allowing for the selection of transgressive interspecific recombinants that can be adapted to specific environments.

  • Principles of Regenerative Medicine

    • 3rd Edition
    • Anthony Atala + 3 more
    • English
    Principles of Regenerative Medicine, Third Edition, details the technologies and advances applied in recent years to strategies for healing and generating tissue. Contributions from a stellar cast of researchers cover the biological and molecular basis of regenerative medicine, highlighting stem cells, wound healing and cell and tissue development. Advances in cell and tissue therapy, including replacement of tissues and organs damaged by disease and previously untreatable conditions, such as diabetes, heart disease, liver disease and renal failure are also incorporated to provide a view to the future and framework for additional studies.

  • Retrovirus-Cell Interactions

    • 1st Edition
    • Leslie Parent
    • English
    Retrovirus-Cell Interactions provides an up-to-date review of the interactions between retroviruses and the cells they infect, offering a comprehensive understanding of how retroviruses hijack cellular factors to facilitate virus replication. Drugs targeting viral enzymes have been developed to treat HIV; the next challenge is to inhibit virus-cell interactions as next generation treatment strategies. Organized according to the retrovirus' replication cycle, this book does not focus exclusively on HIV, but rather includes important findings in other retroviral systems, including animal retroviruses, retrotransposons, and endogenous retroelements to allow broad comparisons on important commonalities and differences.

  • Radical SAM Enzymes

    • 1st Edition
    • Volume 606
    • English
    Radical SAM Enzymes, Volume 606, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on the Characterization of the glycyl radical enzyme choline trimethylamine-lyase and its radical S-adenosylmethionine activating enzyme, Diphathimide biosynthesis, Radical SAM glycyl radical activating enzymes, Radical SAM enzyme BioB in the biosynthesis of biotin, Biogenesis of the PQQ cofactor, Role of MoaAC in the biogenesis of the molybdenum cofactor, Biosynthesis of the nitrogenase cofactor, Bioinformatics of the radical SAM superfamily, The involvement of SAM radical enzymes in the biosynthesis of methanogenic coenzymes, methanopterin and coenzyme F420, and more.

  • Gunner Goggles Neurology

    • 1st Edition
    • Hao-Hua Wu + 1 more
    • English
    The Gunner Goggles Series is the first exam prep resource written by a high-scoring peer group of medical students, ensuring the most practical and efficient study guidance. It organizes topics around the USMLE and NBME content outlines for the required shelf exams. *Please note that the app that was originally available with this title is no longer supported.Gunner Goggles Neurology is one of seven authoritative exam preparation guides that use cutting-edge AR technology to fully prepare you for the NBME clinical shelf exams, the USMLE Step 2 Clinical Knowledge (CK) exam, and successful clinical rotations.

  • Neuro-oncology, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 36-3
    • Patrick Y Wen + 1 more
    • English
    This issue of Neurologic Clinics, edited by Drs. Patrick Y. Wen and Eudocia Quant Lee, will focus on Neuro-oncology. Topiocs include, but are not limited to, Epidemiology of brain tumors, Molecular pathogenesis of brain tumors, Changes in WHO classification of brain tumors, Neurologic and medical management of brain tumors, Grade 2 and 3 Gliomas, Glioblastoma, Benign brain tumors, Primary CNS lymphoma and neurologic complications of systemic lymphoma, Pediatric brain tumors, Brain metastases, Metastatic complications of cancer, Neurologic complications of radiation therapy, Neurologic complications of systemic anticancer therapies, Neurocognitive complaints in cancer patients, and Paraneoplastic syndromes.

  • Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies

    • 1st Edition
    • Sorin Hostiuc
    • English
    Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies offers thorough discussions on preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, sex selection, predictive testing, secondary findings, embryo reduction and the moral status of the embryo, genetic enhancement, and the sharing of genetic data. Chapter contributions from leading bioethicists and clinicians encourage a global, holistic perspective on applied challenges and the moral questions relating the implementation of genetic reproductive technology. The book is an ideal resource for practitioners, regulators, lawmakers, clinical researchers, genetic counselors and graduate and medical students. As the Human Genome Project has triggered a technological revolution that has influenced nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, prenatal genetic testing, and gene therapy, this book presents a timely resource.

  • Cerebral Lateralization and Cognition: Evolutionary and Developmental Investigations of Behavioral Biases

    • 1st Edition
    • Volume 238
    • English
    Cerebral Lateralization and Cognition: Evolutionary and Developmental Investigations of Motor Biases, Volume 238, the latest release in the Progress in Brain Research series, discusses interdisciplinary research on the influence of cerebral lateralization on cognition within an evolutionary framework. Chapters of note in this release include Evolutionary Perspectives: Visual/Motor Biases and Cognition, Manual laterality and cognition through evolution: An archeological perspective, Laterality in insects, Motor asymmetries in fish, amphibians and reptiles, Visual biases and social cognition in animals, Mother and offspring lateralized social interaction across animal species, Manual bias, personality and cognition in common marmosets and other primates, and more.

  • Marine Mammal Ecotoxicology

    Impacts of Multiple Stressors on Population Health
    • 1st Edition
    • Maria Cristina Fossi + 1 more
    • English
    Marine Mammal Ecotoxicology: Impacts of Multiple Stressors on Population Health provides tactics on how to develop a comprehensive methodology for the study of existing threats to marine mammals. By presenting a conservation-biology approach and new and emerging technologies, this work helps provide crucial knowledge on the status of marine mammal populations that not only helps readers understand the ecosystem’s health, but also instigate mitigation measures. This volume provides information that helps investigators unravel the relationships between exposure to environmental stressors (e.g., climate change, pollutants, marine litter, pathogens and biotoxins) and a range of endpoints in marine mammal species. The application of robust examination procedures and biochemical, immunological, and molecular techniques, combined with pathological examination and feeding ecology, has led to the development of health assessment methods at the individual and population levels in wild marine mammals.

  • Polyphenols: Mechanisms of Action in Human Health and Disease

    • 2nd Edition
    • Ronald Ross Watson + 2 more
    • English
    Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products. This very diverse and multi-functional group of active plant compounds contain powerful antioxidant properties and exhibit remarkable chemical, biological and physiological properties, including cancer prevention and cardio-protective activities.

  • Polyphenols: Prevention and Treatment of Human Disease

    • 2nd Edition
    • Ronald Ross Watson + 2 more
    • English
    Polyphenols in Prevention and Treatment of Human Disease, Second Edition authoritatively covers evidence of the powerful health benefits of polyphenols, touching on cardiovascular disease, cancer, obesity, diabetes and osteoporosis. This collection represents the contributions of an international group of experts in polyphenol research who share their expertise in endocrinology, public health, cardiology, pharmacology, agriculture and veterinary science. Researchers from diverse backgrounds will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted insights into the mechanisms of disease. This reference fills a void in research where nutritionists and alternative therapies may be applicable.

  • The Use of Mass Spectrometry Technology (MALDI-TOF) in Clinical Microbiology

    • 1st Edition
    • Fernando Cobo
    • English
    The Use of Mass Spectrometry Technology (MALDI-TOF) in Clinical Microbiology presents the state-of the-art for MALDI-TOF mass spectrometry. It is a key reference defining how MALDI-TOF mass spectrometry is used in clinical settings as a diagnostic tool of microbial identification and characterization that is based on the detection of a mass of molecules. The book provides updated applications of MALDI-TOF techniques in clinical microbiology, presenting the latest information available on a technology that is now used for rapid microbial identification at relatively low cost, thus offering an alternative to conventional laboratory diagnosis and proteomic identification systems. Although the main use of the technology has, until now, been identification or typing of bacteria from a positive culture, applications in the field of virology, mycology, microbacteriology and resistances are opening up new opportunities.

  • Human Genome Informatics

    Translating Genes into Health
    • 1st Edition
    • Christophe Lambert + 2 more
    • English
    Human Genome Informatics: Translating Genes into Health examines the most commonly used electronic tools for translating genomic information into clinically meaningful formats. By analyzing and comparing interpretation methods of whole genome data, the book discusses the possibilities of their application in genomic and translational medicine. Topics such as electronic decision-making tools, translation algorithms, interpretation and translation of whole genome data for rare diseases are thoroughly explored. In addition, discussions of current human genome databases and the possibilities of big data in genomic medicine are presented. With an updated approach on recent techniques and current human genomic databases, the book is a valuable source for students and researchers in genome and medical informatics. It is also ideal for workers in the bioinformatics industry who are interested in recent developments in the field.

  • Biological Emerging Risks in Foods

    • 1st Edition
    • Volume 86
    • English
    Biological Emerging Risks in Foods, Volume 86, addresses the emerging biological risks in food from a global context. Specific sections in this new release include discussions on parasites in foods as an emerging issue and antimicrobial resistance in the food chain. Specific chapters cover Norovirus: the burden of the unknown, Hepatitis E virus: a new foodborne zoonotic concern, Parasites in foods: from a neglected position to an emerging issue, Antimicrobial resistance in the food chain: an emerging global concern, Salmonella in foods: a reemerging problem, Listeria monocytogenes in foods, and Campylobacter in the food chain.

  • The Sourcebook for Clinical Research

    A Practical Guide for Study Conduct
    • 1st Edition
    • Jeff Nelligan + 1 more
    • English
    A single trial is complex, with numerous regulations, administrative processes, medical procedures, deadlines and specific protocol instructions to follow. And yet, there has existed no single-volume, comprehensive clinical research reference manual for investigators, medical institutions, and national and international research personnel to keep on the shelf as a ready reference to navigate through trial complexities and ensure compliance with U.S. Federal Regulations and ICH GCP until The Sourcebook for Clinical Research. An actionable, step-by-step guide through beginning to advanced topics in clinical research with forms, templates and checklists to download from a companion website, so that study teams will be compliant and will find all the necessary tools within this book. Additionally, the authors developed Display Posters for Adverse Events Plus Reporting and Medicare Coverage Analysis that can be purchased separately here: https://www.elsevier... Moreover, The Sourcebook for Clinical Research contains clear information and guidance on the newest changes in the industry to keep seasoned investigators and staff current and compliant, in addition to providing detailed information regarding the most complex topics. This book serves as a quick, actionable, off-the-shelf resource to keep by your side at the medical clinic.

  • Fundamentals of Congenital Minimally Invasive Cardiac Surgery

    • 1st Edition
    • Vladimiro Vida + 1 more
    • English
    Fundamentals of Congenital Minimally Invasive Cardiac Surgery is a first of its kind, fully-illustrated guide that is solely dedicated to the most diffused congenital minimally invasive cardiac surgery procedures. It provides detailed, step-by-step descriptions of surgical maneuvers to underline each aspect of the procedures along with full color drawings and operative pictures to enhance understanding. Each chapter fully describes the preoperative setting, the needed materials and the required technical skills that make specific congenital heart defects amenable to minimally invasive surgical treatment. This is the perfect go-to reference for pediatric and congenital cardiac surgeons, and is also a must-have guide for residents in cardiac surgery who are looking to review the technical aspects and outcomes of utilizing a minimally invasive approach for cardiac surgery.

  • Managing Quality of Fruit and Vegetables

    • 1st Edition
    • Umezuruike Linus Opara
    • English
    Managing Quality of Fruit and Vegetables covers the application of proven and novel industrial approaches to quality management of fresh produce that have become common practice among local and global fresh produce chains while also covering the latest postharvest technologies for maintaining quality and safety. In addition, it addresses the impacts of emerging global challenges, such as climate change, the role of fruit and vegetables on nutrition security, and the development of future postharvest technologies to maintain quality and safety. Both academics and post-graduate students studying fresh produce supply chains and industry professionals will find this book extremely useful.Split into three broad themes, the book brings to light the latest developments on the biochemical and physiological basis for the quality of fruit and vegetables, the industrial approaches to quality management of fruit and vegetables, and the latest advances in postharvest technologies for controlling and maintaining quality.

  • Mitochondria and Longevity

    • 1st Edition
    • Volume 340
    • English
    Mitochondria and Longevity, Volume 340, the latest release in the International Review of Cell and Molecular Biology series reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics with this release focusing on topics such as Mitochondria metabolism and aging, Mitohormesis, Mitochondrial dynamics in the aging stem cell compartment, Mitochondrial proteostasis and aging, Mitochondrial DNA mutations and aging, Mitochondrial sirtuins, NAD+, NADH and aging, Mitophagy and aging, Mitochondria, calcium transport and aging.

  • Neuroinflammation

    • 2nd Edition
    • Alireza Minagar
    • English
    Neuroinflammation, Second Edition, discusses the role inflammation plays in neuro-inflammatory diseases. As research in neuroinflammation has dramatically increased in recent years, this new edition covers all of the new developments and findings since the first publication nearly a decade ago. Comprehensive coverage of topics includes chapters on multiple sclerosis, optic neuritis and Susac syndrome. New chapters cover the latest research in Epilepsy and Neuroinflammation, Pediatric MS, Pediatric Lupus and Traumatic Brain Injury, amongst other topics. Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, brain trauma and meningitis, and it contributes to the generation of pain. Researchers are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage, through tolerance, and to modulation and repair.

  • Neuroepigenetics and Mental Illness

    • 1st Edition
    • Volume 158
    • Bart P.F. Rutten
    • English
    Neuroepigenetics and Mental Illness, Volume 158, the latest release in the Progress in Molecular Biology and Translational Science series, seeks to provide the most topical, informative, and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series seeks to provide readers with in-depth knowledge of important molecular biological aspects of organismal physiology and function, with this release focusing on Neuroepigenetics in mental illness, Neuroepigenetics of development and neurodevelopmental disorder, Neuroepigenetics of aging and age-related neurodegenerative disorders, Neuroepigenetics of prenatal psychological stress, Neuroepigenetics of the HPA axis, Neuroepigenetics of the serotonergic system, and more.

  • Advances in Agronomy

    • 1st Edition
    • Volume 151
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 151, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.

  • Dosage Form Design Considerations

    Volume I
    • 1st Edition
    • English
    Dosage Form Design Parameters, Volume I, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries.

  • Sphingolipids in Cancer

    • 1st Edition
    • Volume 140
    • English
    Sphingolipids in Cancer, Volume 140, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Topics discussed in this updated volume include Mechanisms of ceramide-dependent cancer cell death, Sphingolipids as regulators of autophagy and endocytic trafficking, The role and function of sphingomyelin biosynthesis in the development of cancer, Neutral sphingomyelinases in cancer: Friend or foe?, Sphingolipid rendezvous at the crossroad of NAFLD and senescence, Ceramide signaling and p53 pathways, Sphingolipid regulation of RNA Biology in cancer phenotypes, The role of ceramide-1-phosphate in tumor cell survival and dissemination, and more.

  • Wearable Technology in Medicine and Health Care

    • 1st Edition
    • Raymond K. Y. Tong
    • English
    Wearable Technology in Medicine and Health Care provides readers with the most current research and information on the clinical and biomedical applications of wearable technology. Wearable devices provide applicability and convenience beyond many other means of technical interface and can include varying applications, such as personal entertainment, social communications and personalized health and fitness. The book covers the rapidly expanding development of wearable systems, thus enabling clinical and medical applications, such as disease management and rehabilitation. Final chapters discuss the challenges inherent to these rapidly evolving technologies.

  • Dosage Form Design Parameters

    Volume II
    • 1st Edition
    • English
    Dosage Form Design Parameters, Volume II, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries.

  • Modern Techniques for Food Authentication

    • 2nd Edition
    • Da-Wen Sun
    • English
    Modern Techniques for Food Authentication, Second Edition presents a comprehensive review of the novel techniques available to authenticate food products, including various spectroscopic technologies, methods based on isotopic analysis and chromatography, and other techniques based on DNA, enzymatic analysis and electrophoresis. This new edition pinpoints research and development trends for those working in research, development and operations in the food industry, giving them readily accessible information on modern food authentication techniques to ensure a safe and authentic food supply. It will also serve as an essential reference source to undergraduate and postgraduate students, and for researchers in universities and research institutions.

  • Manejo de la retinopatía diabética

    • 1st Edition
    • Caroline R. Baumal + 1 more
    • Spanish
    La obra analiza los factores de riesgo y la clasificación de la retinopatía diabética, además de estudiar cada modalidad de tratamiento. El título aborda los hot topic con las evidencias más recientes que guiarán al lector a través de cada opción terapéutica. Los casos clínicos que se presentan sirven para mostrar diversos aspectos del tratamiento de la retinopatía diabética complicada. Los autores han elaborado un práctico manual de ayuda para la selección de los fármacos más adecuados y que permitan obtener los mejores resultados para el paciente.

  • Prostate Cancer

    A Case Report
    • 1st Edition
    • Gilles Plourde
    • English
    Prostate Cancer: A Case Report discusses the prevention, treatment modalities, and side effects of the medications used to treat prostate cancer. The book presents the most appropriate information, allowing patient empowerment to make informed decisions on their choice of treatments. Through the analysis of a real case report, the book also discusses the main complication associated with prostate cancer—bone metastasis—and provides information on treatment modalities for lung and liver metastasis. Diet, physical activities and the management of stress are also discussed, as is palliative care and the use of palliative sedation when other treatment modalities have failed. Cannabis, the pros and cons of euthanasia, and concerns raised by society are also covered. Esteemed author Dr. Plourde has more than 12 years’ experience working on drug safety, especially for biologic products involved in the treatment of various cancers. For more than 4 years he has suffered from prostate cancer with metastasis to the lungs and bones. During this time he has learned a lot on prostate cancer from the medical literature and from discussions with various specialists. The case report presented in this book represents his own medical history. Prostate Cancer: A Case Report provides the most relevant and up to date information on the various aspects involved in the screening, diagnosis and treatment of prostate cancer.

  • Darwin’s Pangenesis and Its Rediscovery Part A

    • 1st Edition
    • Volume 101
    • English
    Darwin’s Pangenesis and Its Rediscovery Part A highlights the findings of Darwin's Pangenesis, an expanded cell theory and unified theory of heredity and variation that strengthened his theory of evolution and explained many phenomena of life. Now, new advances and the discovery of circulating cell-free DNA, mobile RNAs, prions and extracellular vesicles are providing new breakthroughs, thus increasing evidence on the inheritance of acquired characters, graft hybridization, and many other phenomena that Pangenesis suggests. Sections of note in this volume include the rationale, criticisms, influence and recent molecular evidence of Darwin's Pangenesis, as well as its relation to the inheritance of acquired characters, which is often included under the blanket term "transgenerational epigenetic inheritance."

  • Emergent Neuroimaging: A Patient Focused Approach, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 28-3
    • Diego B. Nunez
    • English
    This issue of Neuroimaging Clinics of North America focuses on Emergent Neuroimaging: A Patient Focused Approach, and is edited by Dr. Diego B. Nunez. Articles will include: The adult patient with acute neurologic deficit: an update on imaging trends; The patient with thunderclap headache; Imaging considerations in the patient with intracerebral hemorrhage; Emergent neuroimaging in the oncologic and immunosuppressed patient; Emergent neuroimaging during pregnancy and puerperium; Imaging the unconscious “found down” patient in the ED; Neurological emergencies in the pediatric patient including accidental and non-accidental trauma; Head and neck injuries: special considerations in the elderly patient; Current challenges in the use of CT and MRI in suspected cervical spine trauma; Radiation considerations in emergent neuroimaging; Blunt cranio-cervical trauma: Does the patient have a cerebral vascular injury?; New and emerging patient-centered CT imaging and image-guided treatment paradigms for maxillofacial trauma; Acute neurological syndromes beyond stroke: The role of emergent MRI; and more!

  • Microfluidics in Cell Biology: Part A: Microfluidics for Multicellular Systems

    • 1st Edition
    • Volume 146
    • English
    Microfluidics in Cell Biology Part A: Volume 146, the latest release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are sections on Cell monolayers/spheroids... Collective migration in microtubes, Leukocyte adhesion dynamics on endothelial monolayers under flow, Constrained spheroid for perfusion culture, Cells in droplet arrays, Heart on chips, Kidney on chips, Liver on chips and hepatic immune responses, Gut on chips, 3D microvascular model-based lymphoma model, Blood brain barrier on chips, Multi-organ-on-a-chi... for pharmacokinetic analysis, Cancer immunotherapy on chips, and more.

  • Management of High Altitude Pathophysiology

    • 1st Edition
    • Kshipra Misra + 2 more
    • English
    Management of High Altitude Pathophysiology presents a comprehensive overview on the various therapeutic practices and ongoing research relating to the development of more potent and novel formulations for managing high altitude pathophysiology. It provides a detailed application of both herbal and non-herbal therapeutic agents, including their nanoformulations. This important reference provides benefits to the medical and herbal scientific communities, doctors treating patients with high altitude complications, individuals travelling to high altitudes for recreation or work, and scientists working on future drug development.

  • The Immune System and Mental Health

    • 1st Edition
    • Hymie Anisman + 2 more
    • English
    The Immune System and Mental Health fully investigates how immune-related cellular, molecular and anatomical changes impact mental functioning. The book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut, aka, the microbiome, and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. Written by leaders in the field, the book synthesizes basic and clinical research to provide a thorough understanding on the role of immunity in neuropsychiatry. Sociology, psychology, psychiatry, neuroscience and genetics have provided considerable explanations and solutions to some of the most intractable mental-health problems. But researchers are increasingly relying on investigations of the immune system to identify factors that can undermine and impair mental health. This book covers devastating mental-health conditions, such as depression, anxiety, schizophrenia, and autism-like spectrum disorders. In addition, degenerative disorders of the brain, such as Parkinson’s and Alzheimer’s-like dementia are explored.

  • Dehydroepiandrosterone

    • 1st Edition
    • Volume 108
    • Gerald Litwack
    • English
    Dehydroepiandrostero... Volume 108, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics such as Dehydroepiandrostero... Research: Past, Current and Future, Astrocyte Neuroprotection and Dehydroepiandrostero... Mutation of HSD3B2 Gene and Fate of Dehydroepiandrostero... Autophagy and Autophagic Cell Death: Uncovering New Mechanisms Whereby Dehydroepiandrostero... Promotes Beneficial Effects on Human Health, Dehydroepiandrostero... and Cardiovascular Disease, Dehydroepiandrostero... and Experimental Osteoarthritis, The Role of Dehydroepiandrostero... (DHEA) in Skeletal Muscle, Mechanism of Action of Dehydroepiandrostero... and more.

  • The Value of BCG and TNF in Autoimmunity

    • 2nd Edition
    • Denise Faustman
    • English
    The Value of BCG and TNF in Autoimmune Diseases, Second Edition provides an overview on the current research related to TNF induction and the use of the BCG vaccine as a potential treatment approach to diverse forms of autoimmunity, allergies, infections and neurologic diseases. Since the initial conference (2013) and first edition of this book (2014), the field of BCG research has grown considerably. This new edition contains updates on MS and diabetes, and features at least eight additional chapters on new prevention and treatment trials in autoimmunity and allergy, along with a new understanding of the genetics of BCGs.

  • Current Trends and Future Developments on (Bio-) Membranes

    Carbon Dioxide Separation/Capture by Using Membranes
    • 1st Edition
    • Angelo Basile + 1 more
    • English
    Current Trends and Future Developments on (Bio-) Membranes: Carbon Dioxide Separation/Capture by Using Membranes explores the unique property of membranes to separate gases with different physical and chemical properties. The book covers both polymeric and inorganic materials for CO2 separation and explains their mechanism of action, allowing for the development and most appropriate and efficient processes. It also lists the advantages of using membranes instead of other separation techniques, i.e., their low operating costs and low energy consumption. This book offers a unique opportunity for scientists working in the field of membrane technology for CO2 separation and capture.

  • Integrated Analytical Approaches for Pesticide Management

    • 1st Edition
    • Britt Maestroni + 1 more
    • English
    Integrated Analytical Approaches for Pesticide Management provides proven laboratory practices/examples and methods necessary to control pesticides in food and water in various environments. The book presents insights into good laboratory practices and examples of methods used in individual specialist laboratories, thus enabling stakeholders in the agri-food industry to appreciate the importance of proven, reliable data and the associated quality assurance approaches for end product testing for toxic levels of contaminant residues in food. The book is written in a rigorous, but simple, way to make sure that a broad range of readers can appreciate its technical content. The book's practical nature and generic guidelines distinguish it from others in the marketplace.

  • Advances in Marine Biology

    • 1st Edition
    • Volume 79
    • English
    Advances in Marine Biology, Volume 79, the latest release in a series that has been providing in-depth and up-to-date reviews on all aspects of marine biology since 1963, updates on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography. This latest release includes a review of patterns of multiple paternity across sea turtle rookeries, parasites and pathogens in seabirds, progress in marine genomics and bioinformatics, the rise of sea turtle research and conservation, and the potential impacts of offshore oil and gas activities on deep-sea sponges and the habitats they form.

  • Transformative Paleobotany

    Papers to Commemorate the Life and Legacy of Thomas N. Taylor
    • 1st Edition
    • Michael Krings + 3 more
    • English
    Transformative Paleobotany: Papers to Commemorate the Life and Legacy of Thomas N. Taylor features the broadest possible spectrum of topics analyzing the structure, function and evolution of fossil plants, microorganisms, and organismal interactions in fossil ecosystems (e.g., plant paleobiography, paleoecology, early evolution of land plants, fossil fungi and microbial interactions with plants, systematics and phylogeny of major plant and fungal lineages, biostratigraphy, evolution of organismal interactions, ultrastructure, Antarctic paleobotany). The book includes the latest research from top scientists who have made transformative contributions. Sections are richly illustrated, well concepted, and characterize and summarize the most up-to-date understanding of this respective and important field of study.

  • Reproductomics

    The -Omics Revolution and Its Impact on Human Reproductive Medicine
    • 1st Edition
    • José A. Horcajadas + 1 more
    • English
    Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The –Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance. With this book Editors Jaime Gosálvez and José A. Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine.

  • Biscuit, Cookie and Cracker Production

    Process, Production and Packaging Equipment
    • 1st Edition
    • Iain Davidson
    • English
    Biscuit, Cookie, and Cracker Production: Process, Production, and Packaging Equipment is a practical reference that brings a complete description of the process and equipment necessary for automated food production in the food/biscuit industry. The book describes the existing and emerging technologies in biscuit making and production, bringing a valuable asset to R&D personnel and students in food technology and engineering areas. Full of clear illustrations, photos and text describing types of biscuits, cookies and crackers, ingredients, test bakery equipment, dough piece forming, biscuit baking ovens, biscuit cooling and handling, and processing and packaging, this book presents a timely resource on the topic.

  • Coronary Microvascular Obstruction in Acute Myocardial Infarction

    From Mechanisms to Treatment
    • 1st Edition
    • Giampaolo Niccoli + 1 more
    • English
    Coronary Microvascular Obstruction in Acute Myocardial Infarction: From Mechanisms to Treatment provides a comprehensive understanding of the phenomenon of coronary microvascular obstruction (CMVO) that is the main limitation of reperfusion therapies in ST-elevation myocardial infarction. It provides in-depth coverage of the phenomenon of CMVO which heavily affects prognosis by increasing the risk of death and heart failure at follow-up. A first of its kind reference dedicated solely to this topic, it is appropriate for a wide audience, from researchers, to those who aid in the management, prevention and treatment of CMVO.

  • Plasma Medical Science

    • 1st Edition
    • Shinya Toyokuni + 3 more
    • English
    Plasma Medical Science describes the progress that has been made in the field over the past five years, illustrating what readers must know to be successful. As non-thermal, atmospheric pressure plasma has been applied for a wide variety of medical fields, including wound healing, blood coagulation, and cancer therapy, this book is a timely resource on the topics discussed.

  • 3D Printing Applications in Cardiovascular Medicine

    • 1st Edition
    • James K Min + 3 more
    • English
    3D Printing Applications in Cardiovascular Medicine addresses the rapidly growing field of additive fabrication within the medical field, in particular, focusing on cardiovascular medicine. To date, 3D printing of hearts and vascular systems has been largely reserved to anatomic reconstruction with no additional functionalities. However, 3D printing allows for functional, physiologic and bio-engineering of products to enhance diagnosis and treatment of cardiovascular disease. This book contains the state-of-the-art technologies and studies that demonstrate the utility of 3D printing for these purposes.

  • Pediatric Food Preferences and Eating Behaviors

    • 1st Edition
    • Julie C. Lumeng + 1 more
    • English
    Pediatric Food Preferences and Eating Behaviors reviews scientific works that investigate why children eat the way they do and whether eating behaviors are modifiable. The book begins with an introduction and historical perspective, and then delves into the development of flavor preferences, the role of repeated exposure and other types of learning, the effects of modeling eating behavior, picky eating, food neophobia, and food selectivity. Other sections discuss appetite regulation, the role of reward pathways, genetic contributions to eating behaviors, environmental influences, cognitive aspects, the development of loss of control eating, and food cognitions and nutrition knowledge. Written by leading researchers in the field, each chapter presents basic concepts and definitions, methodological issues pertaining to measurement, and the current state of scientific knowledge as well as directions for future research.

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