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Elsevier

Books in Life sciences

  • Bio-Click Chemistry

    Expanding Horizons Beyond the Click
    • 1st Edition
    • Flavia Zacconi + 2 more
    • English
    Bio-Click Chemistry: Expanding Horizons Beyond the Click delves into the dynamic intersection of biocatalysis and click chemistry, providing a comprehensive exploration of these rapidly evolving fields. This book offers in-depth insights into both historical perspectives and the latest advancements, ensuring readers gain a thorough understanding of fundamental principles, practical applications, and future directions. Readers will discover the versatile applications of biocatalysis and click chemistry in pharmaceuticals, biotechnology, biology, biomedicine, nanomedicine, and materials science, equipping researchers, educators, and industry professionals with the tools and techniques needed to foster innovation and real-world impact. Furthermore, the book investigates the emerging trends, challenges, and opportunities in biocatalysis and click chemistry, empowering readers to stay ahead of the curve and drive transformative developments in chemical synthesis and enzymatic engineering. This indispensable guide is designed for researchers, educators, and industry professionals dedicated to advancing their work and exploring new frontiers in chemical synthesis and biocatalytic processes.

  • The Dual Role of Inflammation in Cancer

    • 1st Edition
    • Surajit Pathak + 1 more
    • English
    The Dual Role of Inflammation in Cancer Genesis and Therapy explores the pivotal role inflammation plays in the development and progression of cancer. The book delves into how chronic inflammation creates a microenvironment that supports tumor growth by promoting cellular proliferation, survival, and migration while suppressing immune responses. It traces historical observations, linking inflammation to cancer while also examining how inflammatory cells and mediators contribute to various stages of tumorigenesis. In addition, it discusses the implications of inflammation on cancer treatment, highlighting the potential of anti-inflammatory agents and immunotherapy in targeting the inflammatory tumor microenvironment.By elucidating on the intricate relationship between inflammation and cancer, the book aims to pave the way for more effective and personalized cancer treatment strategies. As such, it is a valuable resource for researchers in immunology and oncology.

  • Legal Issues in Quality for Healthcare Institutions

    • 1st Edition
    • Ramesh Sachdeva
    • English
    Legal Issues in Quality for Healthcare Institutions provides the perspective of practicing physicians, lawyers, and academic legal scholars to comprehensively address the implications for quality of care and patient safety both from a legal, medical, and improvement science standpoint. Hospital administrators, physicians, nurses, researchers, legal scholars, as well as regulatory and compliance officers working in hospitals and acute care facilities will find this to be a helpful resource in understanding and addressing the many facets and issues in the field of medicine and law related to quality and patient safety.

  • Micro(nano)plastics in Organ Systems

    Health Impacts, Challenges, and Future Prospects
    • 1st Edition
    • Charan Singh + 4 more
    • English
    Micro(nano)plastics in Organ Systems: Health Impacts, Challenges, and Future Prospects comprehensively discusses the impact of micro(nano)plastics on human health, analyzing their sources, classification, and exposure pathways, while also exploring their interactions with biological systems, their potential effects on various organ systems, and concerns related to bioaccumulation and toxicity. The book begins with an in-depth analysis of their classification, sources, and exposure pathways, and progressing through interactions with biological systems and the resulting toxicological effects. Furthermore, the book delves into recent advances in detection technologies, the development of more sustainable advances such as bioplastic-based nanoparticles, and the need for regulatory frameworks.The text meticulously examines the implications of these particles on various organ systems—including the gastrointestinal, respiratory, cardiovascular, renal, neurological, reproductive, and metabolic systems—while addressing critical issues such as bioaccumulation, immunological responses, and their potential harmful impact on health. It is an essential resource for toxicologists, environmental scientists, healthcare professionals, public health advocates, and others interested in the implications of micro(nano)plastics on health.

  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 44
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 43 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Content in this new release covers Engineered probiotics for producing phosphoinositol-sn-l... as biosurfactant modulators: Their hydropathy, in potentiating surface tension and scaffold properties into model emulsions.

  • Molecular and Cellular Biology Approaches and Applications in Modern Drug Discovery

    • 1st Edition
    • Mithun Rudrapal + 1 more
    • English
    Molecular and Cellular Biology Approaches and Applications in Modern Drug Discovery is an essential guide that bridges the latest advances in molecular and cellular biology to revolutionize drug discovery. The book explores a wide range of tools and techniques and their applications in drug discovery, including genetic engineering, gene therapy, regenerative medicine, developmental biology, molecular diagnostics, biomarkers, RNA therapeutics, molecular immunology, and vaccine development. The book also considers multi-omics approaches, biophysical methods, epigenetics and epigenomics, biomedical engineering, nanotechnology, artificial intelligence, bioinformatics, structural and computational approaches, and more.This comprehensive volume covers critical domains such as transcriptomics, proteomics, genomics, genetics, and cell signaling pathways, providing an in-depth understanding of their pivotal roles in drug development. It is an invaluable reference for researchers and advanced students working in these areas across molecular biology, biochemistry, pharmacology, biotechnology, and related fields.

  • The Vitamins

    Fundamental Aspects in Nutrition and Health
    • 7th Edition
    • Gerald F. Combs Jr. + 1 more
    • English
    The Vitamins: Fundamental Aspects in Nutrition and Health, Seventh Edition presents both overviews and in-depth discussions of the sources, chemistry, metabolism, and functions of these essential nutrients in physiology and health. Further building upon previous editions of this widely used reference text, readers will gain updated information on the inclusion and interpretation of recent clinical research findings relevant to all vitamins, particularly Vitamins A, D, E, K, C, thiamin, folate and Vitamin B12. The latest information on nutritional deficiencies and ecological approaches to dealing with them along with a section on vitamin-drug interactions is also included.Readers will also find a revised table of signs of vitamin deficiencies in humans and animals, updated information on the roles of the gut microbiome in vitamin synthesis and metabolism, increased focus on vitamins as nutritional supplements, increased focus on vitamin stabilities in foods, including processing and cooking losses and a decision tree addressing the question: “Could I benefit from a vitamin supplement?.” At the end of each chapter, case studies, a quiz, and recommended reading list are included.

  • Personalized Cancer Medicine through Multiomics

    • 1st Edition
    • Mohammad Azhar Aziz + 1 more
    • English
    Personalized Cancer Medicine through Multiomics explores the integration of multiomics to transform cancer diagnosis and treatment. The book delves into how the convergence of genomics, transcriptomics, proteomics, and metabolomics offers a comprehensive understanding of cancer biology, surpassing traditional single-omics approaches. Sections detail advancements in high-throughput technologies and computational methods, including machine learning, that enable the analysis of complex cancer datasets. Additional content discusses how multiomics identifies unique molecular signatures, novel therapeutic targets, and biomarkers, facilitating precise and individualized treatment strategies, particularly for a heterogeneous cancers.For academics, this book serves as an essential resource, compiling fragmented research into a single, coherent volume. It provides foundational knowledge, the latest advancements, and practical applications of multiomics in personalized medicine. Researchers will benefit from interdisciplinary approaches, real-world examples, and cutting-edge methodologies, making it an invaluable reference for advancing their work in oncology.

  • Wearable Smart Sensing Devices for Sustainable Healthcare

    Techniques, Fabrication, Data Collection and Analysis
    • 1st Edition
    • Arpana Parihar + 2 more
    • English
    Wearable Smart Sensing Devices for Sustainable Healthcare: Techniques, Fabrication, Data Collection and Analysis presents a complete overview of the techniques for developing integrated wearable sensors, the systems that power them, and the fabrication issues involved in making them. The book bridges the gap between theory and practice, offering scientific knowledge and practical insights. Written by renowned researchers and industry experts, this book provides valuable understanding and insights into the design, data processing, analysis, and fabrication of wearable sensors that is ideal for academic engineering and scientific researchers, industry engineers, and scientists interested in developing wearable sensor devices.

  • Respiratory Critical Illness During Pregnancy

    Critical Care in Obstetrics
    • 1st Edition
    • English
    Respiratory Critical Illness During Pregnancy: Critical Care in Obstetrics, a volume in the Critical Care Obstetrics series, provides a novel reference for healthcare personnel caring for pregnant women with various health compromises specific to respiratory complications. The book's chapters reflect the growing scope of critical care obstetrics and the increasing importance and recognition of the hospital structure's field, covering the most common respiratory complications that any patient can present during pregnancy, including Asthma, Pulmonary Hypertension and Infection, Cystic Fibrosis, Sleep Disorders, Respiratory failure and more.All intensivists, regardless of primary discipline, must possess a core set of critical care skills that allow them to manage critically ill patients. Here, the authors have gathered the best evidence-based material on respiratory scenarios.

  • New Insights in Pediatric Holter Monitoring and Interpretation

    • 1st Edition
    • Gabriel Cismaru + 2 more
    • English
    New Insights in Pediatric Holter Monitoring and Interpretation is the cutting edge book required by pediatric cardiologists and other professionals who encounter arrhythmias in children. Holter ECG examination has recently undergone significant advances in technology, sensors, and software. Yet, these innovations have been considered primarily in the context of adult patients. On the contrary, New Insights in Pediatric Holter Monitoring and Interpretation uses a case-based methodology to illustrate diagnosis and management of actual pediatric patients. Further, it offers guidance in deciding when referrals are necessary for arrhythmological consultations or ablation interventions. This book also contains novel techniques for detecting and interpreting pediatric arrhythmias. These include the introduction of Poincare graphs, Lorenz plots, and other advanced methods for assessing heart rate variability. New Insights in Pediatric Holter Monitoring and Interpretation modernizes readers' understanding of arrhythmias in children, thus improving the young lives of those in their care.

  • Membrane Transporters and Drug Delivery

    A Comprehensive and Multidisciplinary Guide
    • 1st Edition
    • Elena Puris + 3 more
    • English
    Membrane Transporters and Drug Delivery: A comprehensive and multidisciplinary guide begins with a comprehensive introduction to membrane transporters, their function, structure, and regulation mechanisms. It then moves into the impact of diseases on transporters and how this may affect pharmacokinetics. The book also presents the latest advancements in transporter-mediated drug delivery. A unique feature of this book is its detailed exploration of the methodologies used in transporter research, providing readers with a comprehensive understanding of the strengths and limitations of each approach. It examines the roles of both efflux and influx transporters in drug pharmacokinetics and covers different strategies for utilizing membrane transporters for drug delivery and targeting to specific tissues and cell types. The book concludes with a discussion on regulatory and industrial aspects of transporter-related projects and explores the potential of artificial intelligence in transporter and drug delivery research.Membrane Transporters and Drug Delivery: A comprehensive and multidisciplinary guide begins with a comprehensive introduction to membrane transporters, their function, structure, and regulation mechanisms. It then moves into the impact of diseases on transporters and how this may affect pharmacokinetics. The book also presents the latest advancements in transporter-mediated drug delivery. A unique feature of this book is its detailed exploration of the methodologies used in transporter research, providing readers with a comprehensive understanding of the strengths and limitations of each approach. It examines the roles of both efflux and influx transporters in drug pharmacokinetics and covers different strategies for utilizing membrane transporters for drug delivery and targeting to specific tissues and cell types. The book concludes with a discussion on regulatory and industrial aspects of transporter-related projects and explores the potential of artificial intelligence in transporter and drug delivery research.

  • Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics

    • 1st Edition
    • Lara Scheherazade Milane + 1 more
    • English
    Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics delves into the complex world of intercellular communication biology and its implications on therapeutics. This book covers all areas of intercellular communication and therapeutics in development for different forms of communication, including their role in diseases such as cancer, neurological disorders, metabolic diseases, and inflammatory/immune diseases. Sections provide an introduction, biological targets, challenges, and approaches to overcoming biological barriers and the significance of contact points and mechanisms of internalization. Specifics of tunneling nanotubes, extracellular vesicles, and the immune and non-immune interface in various diseases are covered.Furthermore, the book explores the crosstalk of different forms of intercellular communication and the implications of mitochondrial exchange in the four primary pathological areas. This is an essential resource for researchers, students, and professionals in the field of drug development and delivery. By connecting the dots between extracellular vesicles, tunneling nanotubes, and cell-cell junctions, this book serves as a foundation for further advancements in the science of intercellular communication and it's applications to new drug discovery and delivery.

  • Hybrid Fluoroscopy and Ultrasound Guided Interventional Pain Procedures

    • 1st Edition
    • Manuel Herrero Trujillano + 4 more
    • English
    Hybrid Fluoroscopy and Ultrasound Guided Interventional Pain Procedures ameliorates the dearth of literature covering interventional pain procedures under both X-ray and ultrasound guidance. While existing resources focus on either modality separately, this book fills the gap by providing a consolidated approach, leveraging the strengths of both techniques. By doing so, it ensures practitioners have access to the most versatile and effective imaging methods available. This book is inherently practical, designed to serve as a go-to guide for clinicians facing real-world challenges in pain management. Its organization by body areas facilitates quick access to relevant techniques, while step-by-step guidance and visual aids ensure clarity and ease of understanding. By focusing on clinical relevance, the book empowers practitioners to implement evidence-based imaging interventions with confidence and precision. Hybrid Fluoroscopy and Ultrasound Guided Interventional Pain Procedures has the potential to make a meaningful impact on the field of pain management. By equipping practitioners with cutting-edge imaging techniques and insights, it promises to improve patient outcomes and advance the standard of care. Moreover, its global reach ensures that its benefits extend far beyond geographical boundaries, reaching pain medicine practitioners worldwide.

  • Cryo-EM Methods and Management

    • 1st Edition
    • Edward T. Eng + 2 more
    • English
    Cryo-EM Methods and Management provides a detailed introduction to the latest advances of cryo-EM, from technical innovations to the logistical challenges of maintaining a modern cryo-EM facility. The book consists of four parts, beginning with an overview of cryo-EM. It then moves on to discuss Cryo-EM workflows, with chapters focusing on sample handling and preparation, data collection and hardware, and data procession and visualization. The third part centers on aspects of cryo-EM infrastructure and community building, considering facility set-up and management, monitoring facility performance, instrumentation monitoring , data sharing and standards, and training and development standards. The book then closes with a section looking towards future prospects for cryo-EM. This is an ideal reference for cryo-EM facility and lab managers, providing guidance to the often-overlooked aspect of facility building and management. Additionally researchers working with cryo-EM across molecular biology, structural biology, cell biology and biochemistry will benefit from this book.

  • Novel Approaches to Saturated Fat Replacement in Processed Foods

    • 1st Edition
    • Pintu Choudhary + 1 more
    • English
    Novel Approaches to Saturated Fat Replacement in Processed Foods covers strategies to reduce and replace saturated fat without altering the physicochemical, textural, and full-fat sensory attributes of a final product. Beginning by introducing novel replacement fats such as oleogles, designed lipids, and other plant-based fat mimics, the book demonstrate how these tailor-made oils and fats with improved physical and organoleptic properties can enhance the role of fats and oils in food and nutrition. The book highlights the value of healthier replacement fats in bakery, diary, meat, and frying applications while addressing the nutritional profile and health benefits. It concludes with safety aspects around the use of replacement fats, future trends and developments in the category, the impact ingredients high in saturated fats can have on the environment, and insights into the acceptance of plant-based fat alternatives.

  • Annual Reports in Medicinal Chemistry

    New Approaches in Conjugate Drug Design: Part 1
    • 1st Edition
    • Volume 67
    • English
    New Approaches in Conjugate Drug Design: Part 1, published as Volume 67 of the serial Annual Reports in Medicinal Chemistry, provides a comprehensive overview of current strategies in the design and application of drug conjugates. Chapters cover small molecule drug conjugates, antibody-to-small molecule carrier approaches, antibiotic-derived and terpene-derived antimicrobial conjugates, aptamer-RNA conjugates, and phenolic and metal natural product conjugates. Applications span anticancer, antiviral, antifungal, and theranostic therapies, including photoactivatable therapy and emerging approaches in quantum oncology. The volume serves as a reference on design principles, therapeutic applications, and clinical progress in conjugate-based drug discovery.

  • Pharmaceutical Hot Melt Extrusion

    From Materials Selection to Commercial Production
    • 1st Edition
    • Purnima D. Amin
    • English
    The Practical/User Manual for Making Pharmaceutical Products with Hot Melt Extrusion (HME) is a comprehensive resource addressing the evolving landscape of HME technology. This reference explores the core principles of formulation development, equipment design, process scaling, and regulatory considerations, providing essential knowledge for researchers and industry professionals. It emphasizes innovative, green manufacturing practices, solvent-free processes, and patient-centric delivery systems, making it a vital guide for advancing pharmaceutical and nutraceutical formulations.This reference enhances understanding of cutting-edge HME applications, supporting environmentally sustainable practices and innovative product development for both academia and industry. It equips formulation scientists, R&D professionals, and students with the knowledge to accelerate research, improve efficiency, and translate laboratory innovations into market-ready solutions.

  • Anti-Obesity Drug Development

    Physiology, Pharmacology and Drug Delivery
    • 1st Edition
    • Fadia Salah Youssef + 1 more
    • English
    Anti-Obesity Drug Development: Physiology, Pharmacology and Drug Delivery is a complete reference for pharmaceutical researchers in this key area of research and clinical development. The contents of the book are organized in four parts. The first provides an overview of the foundations and historical development of anti-obesity drugs, including extensive discussion of comorbidities and how they impact drug activity and efficacy. Part two is dedicated to the drug targets involved in the progression of obesity treatment. These include GLPRI and GIPR agonists, Incretin/Glucagon, RM-493 and Liraglutide, Pramlintide and metreleptin, Growth Hormone, FXR and GPR131, and the Gut Microbiota. Part three discusses the most common drugs available in the market and their pharmacological parameters. The final part of the book covers all natural products known to have scientific evidence on the treatment of obesity.Anti-Obesity Drug Development: Physiology, Pharmacology and Drug Delivery is the perfect reference for pharmacology researchers and those involved in new drug development both in academic and corporate environments. Research-physicians, endocrinologists, and nutritionists will also benefit from the comprehensive overview of treatments covered in this book.

  • Introduction to Clinical Engineering

    • 2nd Edition
    • Samantha Jacques
    • English
    The Second Edition of Introduction to Clinical Engineering provides a comprehensive and systematically updated examination of the role of clinical engineering within modern healthcare systems. The text articulates how engineering principles are integrated into patient-centered care delivery, addressing a persistent gap created by the lack of formalized clinical engineering degree programs. It presents a practitioner-focused framework that supports safe and effective medical device use, workflow optimization, and compliance with regulatory requirements. This revised edition expands its scope to reflect the evolving healthcare technology landscape, introducing artificial intelligence at a conceptual level while offering deeper analysis of cybersecurity and healthcare information technology. Particular emphasis is placed on interoperability, hospital technology ecosystems, and the growing interdependencies among clinical systems. Updates to US regulatory policies and emerging cybersecurity risks are fully integrated throughout the text. Designed for healthcare practitioners and educators, Introduction to Clinical Engineering, Second Edition, delivers a coherent, analytically grounded approach to healthcare technology management. It supports evidence-based decision-making, technology lifecycle optimization, and regulatory compliance, while fostering workforce competency development and enabling the translation of theory into efficient, cost effective, and patient-centered clinical outcomes.

  • Advances in Virus Research

    • 1st Edition
    • Volume 126
    • English
    Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Encyclopedia of Pharmacy Practice and Clinical Pharmacy

    • 2nd Edition
    • Zaheer-Ud-Din Babar
    • English
    Encyclopedia of Pharmacy Practice and Clinical Pharmacy, Second Edition, Four-Volume Set is a comprehensive international reference examining the science, practice, policy, and impact of medicines use across healthcare systems. Featuring around 210 chapters written by experts from around the world, it provides authoritative coverage of clinical pharmacy, pharmacy practice research methods, medication safety, medicines optimization, pharmacoepidemiology... pharmacovigilance, health policy, social and administrative pharmacy, pharmacoeconomics, public health, digital health, implementation science, pharmacy education, and workforce development.Designed to support both teaching and research, the encyclopedia brings together foundational knowledge, research methodologies, professional practice, and emerging developments in healthcare delivery. The content is written and referenced with the latest published empirical research.It serves undergraduate and postgraduate students, doctoral researchers, educators, pharmacists, clinicians, healthcare leaders, and policymakers, while supporting programmes in pharmacy, pharmacology, public health, health services research, and healthcare management.By bringing together scientific evidence, practice, and policy, this updated edition provides a valuable resource for understanding the evolving role of medicines and pharmacy in improving patient and population health worldwide.

  • Cultured Meat Production

    Advances, Challenges and Opportunities
    • 1st Edition
    • Zuhaib F. Bhat + 1 more
    • English
    Cultured Meat Production: Advances, Challenges and Opportunities discusses technologies in this exciting field, along with the feasibility of commercial production of fully structured cultured meat and seafood. In addition to covering the latest science, the book examines consumer perception, religious and cultural considerations, and regulatory aspects, such as quality assurance and food safety. The book's chapters are written by academic and industry experts from around the world at the forefront of this exciting field. Researchers, entrepreneurs, and advanced student audiences who are interested in getting up-to-speed on lab-grown meat won't want to miss this timely book.The ever-expanding human population calls for novel ways to produce protein of sufficient quality and quantity, however finite animal and land resources and increasing environmental concerns are already beginning to limit our capacity to produce an adequate protein supply. Novel technologies now allow for the production of cultured meat and seafood, offering a potentially lower carbon footprint and substantially eliminating animal suffering.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 135
    • English
    Advances in Applied Microbiology, Volume 133 presents a comprehensive exploration of the latest innovations in applied microbiology. The book delves into the diverse applications of microbiology across various industries, including agriculture, food production, biotechnology, environmental science, and healthcare. Chapters in this new release include Advances in production related petroleum microbiology, Degradation of Steroid Four-Ring Structures by Comamonas testosteroni: Similar Mechanisms Observed in Various Bacteria Including Mycobacterium tuberculosis, Detoxification of mycotoxins by microorganisms, Use of Deep Eutectic Solvents in Microbial Technology, and more.Through a collection of insightful chapters authored by experts in the field, readers are offered in-depth analyses of cutting-edge research, emerging trends, and practical applications of microbiological principles. From novel microbial technologies to the impact of microbiomes on human health and beyond, this book serves as a valuable resource for researchers, professionals, and students seeking to stay informed and inspired by the exciting advancements.

  • Immunotherapy for Autoimmune Disorders

    Innovations and Insights
    • 1st Edition
    • Arun Kumar Singh + 4 more
    • English
    Immunotherapy for Autoimmune Disorders: Innovations and Insights revolutionizes the therapeutic paradigm for autoimmune illnesses, offering new perspectives over traditional medication therapies. This complete and accessible resource examines how immunotherapy teaches the immune system to detect and fight targeted cells, enhancing the body's immune response by providing additional components to strengthen its defense mechanisms. The book covers a wide range of topics, including the pathophysiology, diagnosis, and classification of autoimmune diseases, the immunopathogenesis of these disorders, and the development and application of monoclonal antibodies. It explores immune checkpoint inhibitors, T-cell modulation therapies, cytokine targeting therapies, B-cell depletion strategies, and more.Additionally, it addresses immunomodulatory agents, small molecules, personalized immunotherapy approaches, and the application of immunotherapeutic strategies for specific autoimmune diseases. Future directions and emerging therapies, as well as regulatory and ethical considerations, are also discussed. This is essential reading for medical professionals, researchers, and students seeking to learn about immunotherapy as an alternative approach to treating autoimmune disorders.

  • Microbial Biofilms and Cancer - Part B

    • 1st Edition
    • Volume 225
    • English
    Biofilms in Cancer: Molecular Mechanisms, Host Reprogramming and Tumor Progression presents a focused and multidisciplinary examination of the emerging role of microbial biofilms in cancer biology. The volume challenges the conventional view of biofilms as merely persistent microbial communities and highlights their potential contribution to chronic inflammation, host-cell reprogramming, tumor development, cancer progression, and invasion.The book begins by establishing biofilms as an underestimated threat in cancer, providing a foundation for understanding the complex interactions between microbial communities and malignant tissues. It subsequently explores the molecular mechanisms through which quorum sensing and biofilm-associated signals can influence host-cell behavior, together with the mechanisms underlying biofilm formation and microbial interaction with host cells.A major focus of the volume is the biofilm-mediated modulation of the tumor microenvironment. The chapters examine how biofilm components can dysregulate cytokines and chemokines, sustain chronic inflammatory responses, and create conditions that may favor tumorigenesis. Particular attention is given to the transition from persistent microbial colonization and inflammation to malignant transformation and tumor progression.The book also provides organism- and cancer-specific perspectives, with detailed discussions of the contribution of Porphyromonas gingivalis and Candida biofilms to oral squamous cell carcinoma, as well as the involvement of Helicobacter pylori, Fusobacterium nucleatum, P. gingivalis, Escherichia coli, and Candida across specific cancer contexts. These chapters highlight the diversity of microbial strategies and host responses associated with biofilm-linked malignancies.The concluding perspective addresses the emerging role of biofilms in cancer invasion, bringing together microbial persistence, host-cell interaction, inflammatory signaling, and tumor progression into an integrated framework. Collectively, the volume provides a comprehensive overview of the biofilm–host–inflamm... axis, emphasizing how microbial communities may influence different stages of cancer biology.This book will be valuable to microbiologists, cancer biologists, oncologists, molecular biologists, immunologists, oral health researchers, infectious-disease specialists, biotechnologists, clinicians, and postgraduate researchers seeking to understand the increasingly important intersection of microbial biofilms and cancer. It also provides a foundation for identifying new research questions, biomarkers, preventive strategies, and potential therapeutic targets at the interface of infection and malignancy.

  • Metabolomic Phenotyping for the Future of Personalized Medicine

    Beyond the Biomarkers
    • 1st Edition
    • Jacopo Troisi + 1 more
    • English
    Metabolomic Phenotyping for the Future of Personalized Medicine: Beyond the Biomarkers takes a critical look at the advancements in the field. It begins by explaining the essential steps of metabolomics analysis—from sample collection to data interpretation—while exploring how these workflows pave the way for targeted medical applications. With a focus on precision, it shows how metabolomics provides key insights into the mechanisms behind diverse phenotypes, making it an indispensable asset for biomedical research. The second section dives into the transformative results achieved in major medical domains through metabolomics, detailing how this emerging science contributes to understanding complex disease mechanisms.The book also outlines the international regulatory framework essential for conducting research within this field, ensuring compliance and ethical standards. By combining practical guidelines with visionary insights, this text serves as a cornerstone for future strides in personalized medicine and highlights the growing influence of metabolomics in shaping tomorrow’s healthcare systems.

  • Plant-Based Proteins in Food Processing and Production

    • 1st Edition
    • Claire Darizu Munialo
    • English
    Plant-Based Proteins in Food Processing and Production addresses the urgent global challenge of climate change by exploring sustainable alternatives to animal-derived proteins. With growing concerns about the environmental impact of food production, this book provides a timely and comprehensive examination of plant-based proteins, focusing on their potential to reduce greenhouse gas emissions while meeting nutritional and functional food requirements. The book offers an in-depth exploration of plant-based alternative proteins through four key sections. The first section covers a variety of plant protein sources, including soy, pea, oil-producing plants, seaweed, and novel emerging proteins. The second section focuses on the processing techniques, such as extraction, modification, and innovative technologies for producing plant-based meat alternatives. The third section examines practical applications, including plant-based alternatives to milk, meat, egg, and fat replacers, as well as the role of protein blends in product formulation. Finally, the book addresses challenges and opportunities related to sensory qualities, consumer acceptance, sustainability, and future prospects in plant-based food production.Plant-Bas... Proteins in Food Processing and Production is an essential resource for professional food scientists in the engineering and manufacturing of plant-based protein products, as well as graduate students and researchers in food science and technology. By combining scientific insight with practical applications, this book equips readers with the knowledge needed to innovate and advance sustainable protein solutions, supporting the evolution of the global food industry toward a more environmentally responsible future.

  • Microbial Fertilizers

    Innovations and Applications for Sustainable Agriculture
    • 1st Edition
    • Ajay Kumar + 3 more
    • English
    Microbial Fertilizers: Innovations and Applications for Sustainable Agriculture explores the latest developments, applications, and challenges in the formulation and commercialization of novel microbial-based biofertilizers. Covering a wide array of topics, the book begins by covering the selection and diversity of microbial fertilizers. It explores the molecular and biochemical mechanisms of their plant-microbe interactions and how they can enhance nutrient availability and improve environmental stress tolerance. Additionally, the book addresses the commercialization and market trends of microbial fertilizers like the use of formulation technologies to improve microbial viability and stability in various product formats for better practical application.The book also explores cutting-edge omics approaches that facilitate comprehensive profiling of microbial communities and their roles in soil fertility and plant health as well as innovative technologies like the integration of synthetic biology and genetic engineering to tailor microbial strains for specific functions and the use of nanotechnology with microbial fertilizers for targeted nutrient delivery and controlled release systems. With a focus on overcoming the environmental challenges and leveraging opportunities for sustainable application, this book is an essential resource that provides insights into how microbial fertilizers can contribute to sustainable agriculture in the face of climate change.

  • Comparative Fish Immunology

    • 1st Edition
    • Volume 42
    • English
    Comparative Fish Immunology, Volume 42 in the Fish Physiology series, presents chapters written by leading experts. Covering a broad range of topics, this edition explores the evolution and function of immune systems in fish, with particular attention to both innate and adaptive immune mechanisms across diverse aquatic species. Chapters examine adaptive immunity in jawless vertebrates and the unique VLR system, the role of antimicrobial peptides in teleost infections, and the use of zebrafish as a model for studying innate immune responses. Additional contributions explore pharyngeal mucosal lymphoid structures, the evolutionary origins of germinal centers in fish, and mechanisms of antigen presentation in teleosts.Other chapters address microbiota–host immune interactions, emerging insights into teleost neuroimmunology, and the modulation of immune function through behavioral fever. Together, these contributions provide a comprehensive overview of current discoveries and evolving perspectives in fish immunology, offering valuable insights for researchers, immunologists, and aquatic biologists interested in the physiology and immune biology of fishes.

  • Plant-Induced Systemic Resistance

    Mechanisms and Applications Against Biotic and Abiotic Stressors
    • 1st Edition
    • Sengottayan Senthil-Nathan + 2 more
    • English
    Plant-Induced Systemic Resistance: Mechanisms and Applications Against Biotic and Abiotic Stressors examines how intrinsic defense signaling and state-of-the-art biotechnologies can fortify crops while reducing reliance on chemical inputs. This rigorous treatment unpacks the biochemical circuitry of induced immunity, the networks coordinating defense, and the innovative molecular biology tools that empower durable protection under a variety of stress triggers. Against the backdrop of rising pest pressures, evolving resistance patterns, and environmental concerns, it presents a forward-looking framework for integrating host defenses within comprehensive crop protection initiatives.This volume traces a clear trajectory from foundational concepts to precision management solutions, delivering data-driven methodologies, decision support tools, and scalable practices for sustainable agriculture, enriched by real-world case studies that illustrate adoption across research, extension, and industry contexts. Governance, regulatory considerations, and societal implications are woven throughout to ensure responsible innovation.Bridging lab-derived knowledge with field-ready interventions, this essential resource opens avenues for interdisciplinary collaboration to bolster plant resilience against various biotic and abiotic stressors, expanding the toolkit for integrated crop protection.

  • Pediatric Pulmonology

    A Global Handbook for Clinical Care Providers
    • 1st Edition
    • Allen J. Dozor
    • English
    Pediatric Pulmonology: A Global Handbook for Clinical Care Providers provides an in-depth exploration of pediatric respiratory diseases, offering a detailed examination of various conditions, diagnostic techniques, and treatment protocols. The book covers a wide range of topics, from the assessment of children with respiratory diseases to specific conditions such as asthma, cystic fibrosis, and bronchopulmonary dysplasia. Each chapter is contributed to by leading experts in the field, ensuring that the content is both authoritative and up-to-date. These crucial, practical skills are essential when a pediatric patient's first point-of-care is not a respiratory specialist.This is especially true of medical treatment in resource-poor areas. The book includes "how to guides" on vital procedures such as spirometry, chest imaging, and the management of respiratory emergencies. It also addresses respiratory diseases in newborns, the impact of environmental factors on children's respiratory health, and the unique challenges faced by children with neurologic and neuromuscular diseases. This comprehensive approach ensures that non-specialists gain a holistic understanding of pediatric respiratory diseases and their management.

  • Remote Sensing for Vegetation Monitoring

    Technologies, Applications and Models
    • 1st Edition
    • Prem Chandra Pandey + 3 more
    • English
    Remote Sensing for Vegetation Monitoring: Technologies, Applications and Models provides insight on the pivotal role that remote sensing plays in vegetation monitoring. As traditional field assessments face challenges due to inaccessible study sites and lengthy data collection, this book offers a comprehensive view of remote sensing applications for monitoring various vegetation ecosystems, including forests, grasslands, mangroves, and agriculture. The book presents a coherent and consistent structure, across five sections that build upon prior knowledge and detail the quantitative and qualitative assessments made possible through remote sensing technologies. Remote Sensing for Vegetation Monitoring: Technologies, Applications and Models caters to a diverse audience, including researchers and practitioners seeking to navigate the evolving landscape of vegetation monitoring through case studies, new algorithms and state-of-the-art methods.

  • Advances in Applied Mechanics: Letters

    • 1st Edition
    • Volume 63
    • English
    Advances in Applied Mechanics, Volume 63 highlights new advances, with this volume presenting interesting chapters written by an international board of authors. Chapters in this release cover higher order discontinuous Galerkin finite element methods for the contact problems, Anisotropic Recovery-Based Error Estimators and Mesh Adaptation Tailored for Real-Life Engineering Innovation, Adaptive mesh refinement on Cartesian meshes applied to the mixed finite element discretization of the multigroup neutron diffusion equations, and more. Other sections cover a posteriori error analysis for Finite Element approximation of some groundwater models Part I: Linear models, a posteriori error estimates for low frequency electromagnetic computations, and more.

  • Practice of Neurocritical Care in Resource Limited Countries

    • 1st Edition
    • Hemanshu Prabhakar + 2 more
    • English
    Practice of Neurocritical Care in Resource Limited Countries offers a comprehensive examination of the unique challenges and practical strategies for delivering neurocritical care in low- and middle-income countries (LMICs). As the prevalence of neurological emergencies continues to rise in these regions, this book addresses the critical need for effective management in resource constrained environments. It begins by exploring the landscape of neurocritical care, including common neurological emergencies and their epidemiology in LMICs. The content outlines foundational principles of patient assessment and monitoring, as well as advanced management strategies for conditions such as traumatic brain injury, stroke, and spinal cord injury. Special attention is given to the nuances of caring for diverse patient populations, including pediatric and geriatric patients. Additionally, this book highlights the essential role of pain management, and nutritional support, in neurocritical settings. With contributions from experts across various LMICs, this resource emphasizes innovative approaches to training and capacity building, empowering healthcare professionals to provide high-quality neurocritical care despite the challenges of limited resources. This book is an invaluable tool for clinicians and educators dedicated to improving outcomes for neurologically ill patients in lesser-resourced healthcare systems.

  • Baicalin

    Pharmacology, Clinical Applications, and Future Prospects
    • 1st Edition
    • Xiao Ma + 2 more
    • English
    Baicalin: Pharmacology, Clinical Applications, and Future Prospects is an essential reference for researchers and pharmaceutical professionals seeking to deepen their understanding of baicalin, a potent flavonoid with significant therapeutic potential. This comprehensive guide consolidates foundational knowledge and recent advancements in baicalin research, addressing critical aspects such as efficacy, toxicity, and pharmacokinetics. By systematically exploring baicalin’s drug development potential, this book serves as a vital resource for those aiming to make original contributions to the field.The book is organized into three main parts, beginning with the Foundations of Baicalin Research, which explores the historical and traditional uses of baicalin, extraction methods, and modern research advancements. The second part, Pharmacology of Baicalin, provides an in-depth analysis of its mechanisms of action, bioavailability, and pharmacokinetic parameters, while also presenting current applications for various diseases, including pulmonary, liver, cardiovascular, and nervous system disorders. Finally, the Prospects section addresses future directions in drug delivery and administration, focusing on innovative approaches to enhance baicalin’s bioavailability and therapeutic efficacy.By balancing scientific rigor with accessibility, this book is tailored for PhD students, postdoctoral researchers, and pharmaceutical professionals. It highlights cutting-edge research and practical applications, empowering readers to explore the full potential of baicalin in drug development and clinical practice. Whether you are new to the field or an experienced researcher, “Baicalin: Pharmacology, Clinical Applications, and Future Prospects” offers invaluable insights that will enhance your understanding and inspire future research endeavors.

  • Female Reproductive Endocrinology Across the Lifespan, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 55-4
    • Danit Ariel
    • English
    In this issue of Endocrinology and Metabolism Clinics, guest editor Dr. Danit Ariel brings her considerable expertise to the topic of Female Reproductive Endocrinology Across the Lifespan. Top experts examine both common and complex reproductive endocrine disorders, integrating mechanistic insights with practical clinical considerations. Articles discuss nonhormonal interventions for menopausal symptoms, innovative approaches for hyperandrogenism, long-term endocrine risks after gestational diabetes and preeclampsia, and much more.

  • AI-Driven Diagnostics for 6G-Enabled Smart Healthcare

    • 1st Edition
    • Sangeeta Kumari + 3 more
    • English
    AI-Driven Diagnostics for 6G-Enabled Smart Healthcare explores the transformative integration of artificial intelligence (AI) and next-generation 6G networks in the healthcare sector. The book begins by highlighting the evolution of healthcare technology and the critical role of AI-driven diagnostics, emphasizing how 6G facilitates real-time, ultra-reliable communication. Key features of 6G, such as ultra-low latency and massive connectivity are discussed, showcasing their impact on advanced healthcare applications like remote diagnostics and patient monitoring. In addition, the integration of AI in medical diagnostics is examined, focusing on machine learning and deep learning techniques that enhance disease detection through medical imaging and clinical data analysis.Users will also find content that explores the benefits of remote patient monitoring, particularly for underserved populations, and delves into edge AI for localized, low-latency diagnostic processing. Other sections cover real-time imaging diagnostics are highlighted and address predictive analytics, detailing AI models that forecast diseases and the role of IoT devices and wearables in healthcare diagnostics. Final sections cover ethical considerations and regulatory challenges.

  • Nanotechnological Innovations for Dairy Products

    Applications from Farm to Fork
    • 1st Edition
    • Ravi Pandiselvam + 2 more
    • English
    Nanotechnological Innovations for Dairy Products: Application from Farm to Fork offers an overview of the prominent, cutting-edge nanotechnology applications throughout the entire dairy supply chain, from farm-level production to consumer consumption. It will explore how nanotechnology can improve milk quality, extend shelf life, enhance nutritional value, and enable controlled release of bioactive compounds. It will also highlight the importance of ethical considerations, consumer acceptance, and transparency in the adoption of nanotechnology in the dairy industry. Written and edited by a team of international experts, Nanotechnological Innovations for Dairy Products: Application from Farm to Fork will guide researchers and industry stakeholders in implementing nanotechnology solutions in their practices and inspire future research and discoveries.

  • Starch Blends and Their Applications

    Sustainable Packaging Solutions
    • 1st Edition
    • Rafael Audino Zambelli
    • English
    Starch Blends and Their Applications: Sustainable Packaging Solutions, a new volume in the Applications of Starches in Food and Packaging series, discusses the latest advancements in production techniques and modification strategies for enhancing the functionality and compatibility of starch blends in multicomponent systems. The book presents case studies and real-world applications of starch blends in food processing, biodegradable materials, biomedical applications, and more, showcasing their diverse functionalities and potential benefits. Chapters also address challenges, opportunities, and future trends in starch blends research and development, offering insights into emerging technologies and areas for further exploration.Written by leading experts in the field, this book equips its audience with the knowledge, skills, and insights needed to navigate the complexities of starch blends and harness their potential in diverse applications.

  • Probiotics

    A Comprehensive Exploration of Health Benefits and Innovation
    • 1st Edition
    • Ranbir Chander Sobti
    • English
    Probiotics: A Comprehensive Exploration of Health Benefits and Innovation explores the potential of probiotics and their fundamental role in human health and disease prevention. The book offers a thorough understanding of how beneficial microorganisms can enhance overall well-being and potentially transform treatment approaches across multiple disciplines. The first section lays the groundwork by exploring the fundamentals of probiotics, prebiotics, and their interactions with the human microbiome, while the second section examines the role of probiotics in disease prevention and management, highlighting their impact on conditions such as diabetes, obesity, and mental health.The third section discusses specialized applications of probiotics in women's health, pediatrics, and geriatrics, as well as their innovative uses in skin care and nutrition. Finally, the fourth section investigates the future potential of probiotics in synthetic biology, in personalized health, and in combatting antibiotic resistance. With contributions from a diverse group of experts in the field, the book serves as an interdisciplinary resource for researchers, clinicians, and industry professionals eager to explore the therapeutic potential and benefits of probiotics.

  • Grodner's Nutritional Foundations and Clinical Applications

    A Nursing Approach
    • 9th Edition
    • Sylvia Escott-Stump + 2 more
    • English
    Master the nurse’s role in nutrition and nutrition therapy to promote health! Grodner's Nutritional Foundations and Clinical Applications: A Nursing Approach, 9th Edition, describes nutritional healing and wellness from the nurse’s perspective. It introduces essential nutrients, then shows how nutrition principles apply to patients in real-world practice, both for normal and therapeutic nutrition. This edition is updated with the most current guidelines and the latest nutrition research. Written by noted educators Sylvia Escott-Stump and Suzanne Dorner, this leading nutrition text promotes healthy diets and shows how nutrition may be used in preventing and managing diseases and disorders.

  • Bioactives from Aquatic Side Streams

    Innovative Extraction Procedures and Applications
    • 1st Edition
    • Sakhi Ghelichi + 2 more
    • English
    Bioactives from Aquatic Side Streams: Innovative Extraction Procedures and Applications examines the untapped potential of aquatic resources and byproducts as a rich source of bioactive compounds, including proteins and peptides, omega-3 fatty acids, phenolic compounds, pigments, vitamins, and minerals. With a focus on sustainable practices, this book explores the identification, extraction, characterization, and application of these bioactive compounds across various industries. Early chapters characterize the bioactivity of key compounds, describe the aquatic side streams available for sourcing these compounds, and provide a high-level overview of their extraction techniques.Central chapters focus on these processes for specific bioactive compounds, including hydrolysates, peptides, omega-3 oil, phospholipids, collagen, gelatin, chitin, chitosan, minerals, pigments, and more. Concluding chapters explore emerging techniques, market hurdles and possible solutions, and regulatory considerations for the sustainable sourcing of bioactive compounds from aquatic side streams. By equipping readers with the knowledge to develop new products that enhance existing ones, this book promotes the innovative use of aquatic byproducts for a more sustainable future.

  • Building Blocks of Neuroimmunometabolism

    From Molecular Pathways to Therapeutic Strategies
    • 1st Edition
    • Sachchida Nand Rai + 2 more
    • English
    Building Blocks of Neuroimmunometabolis... From Molecular Pathways to Therapeutic Strategies offers an authoritative exploration of the intricate relationship between the immune system and neurodegenerative diseases. This essential resource addresses the critical gap in understanding how immune responses and metabolic processes jointly influence the onset and progression of conditions such as Alzheimer’s, Parkinson’s, and multiple sclerosis. The book provides an examination of key molecular pathways and cellular interactions, emphasizing the role of immunometabolism in disease mechanisms. Beginning with an introduction to the concept of immunometabolism, it explores the connections between the immune and nervous systems, setting the stage for understanding neurodegenerative diseases.In addition, the book discusses pivotal topics such as the role of microglia and macrophages in neuroinflammation, the metabolic regulation of T cells, and the impact of oxidative stress and mitochondrial dysfunction. The gut-brain axis is examined for its influence on brain health, alongside innovative therapeutic strategies targeting immunometabolic pathways and lifestyle interventions.

  • Advances in Transfusion Medicine

    A Practical Handbook
    • 1st Edition
    • Parmatma Prasad Tripathi
    • English
    Advances in Transfusion Medicine: A Practical Handbook presents a detailed overview of transfusion medicine, beginning with blood components and derivatives therapy, including RBC, platelet, and plasma transfusions, as well as hematopoietic stem cell therapy. The book addresses patient blood management, focusing on practical applications and specific considerations in various populations. Safety practices in transfusion, including blood donation strategies and reactions are also covered. In addition, emerging therapies and technologies, such as artificial red blood cells and gene therapy are explored alongside global health challenges related to blood safety and shortages.The role of immunohematology and genomics is highlighted, along with cellular therapy applications, ethical considerations, and a discussion on pediatric transfusions and guidelines for managing transfusions in children. Miscellaneous topics like emerging infections and pathogen reduction technologies complete the overview, emphasizing current practices and future directions in the field.

  • Technological Fusion in Experimental Medicine and Biology

    • 1st Edition
    • Shubham Mahajan + 1 more
    • English
    Technological Fusion in Experimental Medicine and Biology examines how artificial intelligence, omics technologies, nanotechnology, and biomedical engineering are converging to reshape experimental medicine. The book presents an integrated, end‑to‑end translational framework connecting hypothesis development, experimentation, multimodal data integration, AI‑driven analysis, and clinical translation. It covers the core enabling technologies and the models that link diverse tools into coherent biomedical workflows. Content is structured across foundational concepts, technologies, workflow integration, application domains, and real‑world case studies, supported by schematic workflows, decision frameworks, and ethical and regulatory perspectives. Chapters emphasize deep learning, reproducible research, and data governance, with case studies in cancer, cardiovascular, and neurological research. The book provides researchers, educators, and lab leaders with a unified framework for interdisciplinary research, teaching, and translational innovation.

  • Chia Seeds

    Applications in the Agri-food Industry
    • 1st Edition
    • Shivani Pathania + 2 more
    • English
    Chia Seeds: Applications in the Agri-food Industry is a comprehensive guide to the properties of chia biomass (seeds, leaves, and ingredients/products thereof) and their utilization in the agri-food industry and beyond. The book is based on the analysis of chia value chain and summarizes the scientific, technical, and health aspects of chia (Salvia hispanica L.). Divided into 3 sections, it fills a critical gap in the literature by providing a comprehensive overview of chia biomass available to address key global bioeconomy and United Nation Sustainable Development Goals (SDGs) challenges.User will find advanced information for the utilization of chia-based biomass based on their specific properties, application of eco-efficient technologies for their processing and conversion into a variety of products for different groups of consumers, including those with special needs (e.g. celiac patients, vegans and vegetarians). In addition, the book offers practical guidance on the development of new value chains and their integration within the existing agri-food systems.

  • Sensory Analysis in the Development and Consumer Perception of Dairy Products

    • 1st Edition
    • Adriano Gomes da Cruz + 2 more
    • English
    Sensory Analysis in the Development and Consumer Perception of Dairy Products aims to present and discuss the methodologies that can be used in the development of dairy products and the evaluation of consumer perception of novel dairy foods. Divided into four sections, the book presents the fundamental concepts of sensory analysis using classical/traditiona... methodologies and innovative methods, including neuroscientific approaches. Case studies demonstrate how these methods have been successfully put into practice during product testing. Sensory Analysis in the Development and Consumer Perception of Dairy Products is a must-have resource for researchers interested in the sensory analysis of dairy, particularly those interested in developing and testing new products.

  • Technological Applications of Fungal Enzymes in Biorefinery and Bioproducts Development

    Volume 2
    • 1st Edition
    • Manikant Tripathi + 1 more
    • English
    Technological Applications of Fungal Enzymes in Biorefinery and Bioproducts Development provides a thorough understanding of technological advances and utilization of fungal enzymes for the development of useful products through using advanced microbial biotechnological techniques. This is the second of two volumes that provide a comprehensive overview of the utilization of fungal enzymes for biorefinery and bioproduct development. Volume 2 discusses basic and technological interventions in fungal enzyme applications exploring biotechnological strategies and how they can address challenges and solutions in the processes involved in fungal enzyme applications. The book also offers practical examples and case studies of technology advances in fungal enzyme-mediated development of biofuels and bioproducts. In combination with Volume 1, this book offers a holistic view of the potential and challenges of engineered fungal enzymes for researchers, scientists, and industry professionals seeking to deepen their knowledge of fungal enzymes and their role in biochemical advances.

  • Applied Enzymology and Biocatalysis

    Mechanistic Principles for Industrial and Clinical Applications
    • 1st Edition
    • Muhammad Sajid Hamid Akash + 2 more
    • English
    Applied Enzymology and Biocatalysis: Mechanistic Principles for Industrial and Clinical Applications examines the molecular mechanisms, kinetics, and engineering of enzymes that underpin their growing use across biotechnology, medicine, and industry. The book provides a comprehensive exploration of how enzymatic processes can be optimized and adapted to meet the evolving needs of biomanufacturing, sustainable chemistry, and therapeutic innovation. With a clear emphasis on mechanistic insight and translational relevance, the book covers enzyme structure–function relationships, catalytic mechanisms, protein engineering, directed evolution, and computational design. It further integrates applications in biocatalysis, nanobiotechnology, biosensor development, green chemistry, and synthetic biology. Special attention is given to the clinical and diagnostic uses of enzymes, including their role in drug discovery, metabolic engineering, and precision healthcare. This book serves as a detailed reference for understanding the principles and applied aspects of enzyme science in modern biotechnology. It is a valuable resource for biochemists, molecular biologists, biotechnologists, pharmaceutical researchers, process engineers, and graduate students seeking to expand their expertise in enzymology and biocatalytic innovation.

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