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Elsevier

Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

  • Biosynthesis of Tetrapyrroles

    • 1st Edition
    • Volume 19
    • P.M. Jordan
    • English
    The study of the structure and function of tetrapyrrolic compounds has excited the interests of organic chemists, biochemists, botanists and biologists for more than a hundred years. Scientific analysis began with the first descriptions of naturally occurring porphyrins, and progress was made towards understanding the structure of chlorophyll. This was followed by the use of newly available isotopes of carbon and nitrogen to investigate the formation of porphyrins in biological systems. Further discoveries led to the elucidation of the atoms in protoporphyrin IX, made possible by the application of physical methods, such as NMR spectroscopy and recombinant DNA technology. The present volume discusses many more exciting and unexpected developments which have been made in the field over the last ten to fifteen years. While not all questions have yet been answered, the forum is set for a great scope of further research in the study of tetrapyrroles.• Of interest to biochemists, organic chemists and plant scientists• The book focusses on the exciting and unexpected developments in the field of tetrapyrolles over the last ten years• It paves the way for future research in this area

  • Biosensors

    • 1st Edition
    • Volume 11
    • F. Scheller + 1 more
    • English
    Biosensors combine the unique properties of biological systems to selectively recognize and convert molecules with the benefits of physicochemical sensor technology, such as high sensitivity, simplicity of operation and mass production, and modern electronics. Consequently, their development is closely related to progress in two branches of high technology - biotechnology and microelectronics. This book not only presents the state-of-the-art of biosensor research and development to the specialist, but also introduces the layman to the fundamentals of the subject. The relevant features of physicochemical transducer elements as well as biochemical recognition molecules (enzymes, antibodies, receptors) are outlined. Biochemical and biotechnological aspects of biomolecule immobilization and the interplay of biochemical reactions and mass transfer processes are comprehensively treated with regard to their impact on successful sensor design. Examples of immobilization methods are described in detail. The employment of coupled enzyme reactions, higher integrated biocatalytic systems (cell organelles, microbes, tissue sections) and immunocomponents in biosensors is covered extensively. Optical, thermometric, piezoelectric and particularly electrochemical biosensors for more than 100 analytes are presented, including immunosensors. The relative merits and limits of biosensors are discussed using several examples of their application in clinical chemistry, bioprocess control and environmental monitoring. Finally, the application of biosensors in medicine, biotechnology, food industry and environmental control is discussed, including commercialization and problems to be addressed in future research.

  • Cytochrome P450

    Protein-Dna Interactions
    • 1st Edition
    • Volume 206
    • John N. Abelson + 1 more
    • English
    This volume represents the first collection of methodological approaches to P450 investigation which includes the use of molecular biological techniques. It is designed for use by those who study the P450 super family. Methods are presented for the identification and characterization of unique forms of P450 mRNA and protein, for expression of P450s in heterologous systems, for the study of human P450s, and for the characterization of P450s in different tissues.

  • Techniques for the Study of Mycorrhiza

    • 1st Edition
    • Volume 23
    • English
    Volumes 23 and 24 of this highly acclaimed series focus on methods used for the study of both ectomycorrhiza and vesicular-arbuscular mycorrhiza. Written by a team of international experts, these volumes comprise the most extensive compilation of methods available on this topic.

  • Advances in Cancer Research

    • 1st Edition
    • Volume 57
    • English

  • Molecular Design and Modeling: Concepts and Applications, Part A: Proteins, Peptides, and Enzymes

    • 1st Edition
    • Volume 202
    • John N. Abelson + 1 more
    • English
    Computer-based design and modeling, computational approaches, and instrumental methods for elucidating molecular mechanisms of protein folding and ligand-acceptor interactions are included in Volumes 202 and 203, as are genetic and chemical methods for the production of functional molecules including antibodies and antigens, enzymes, receptors, nucleic acids and polysaccharides, and drugs.

  • Evolutionary Biology

    • 1st Edition
    • Volume 1
    • Edward Bittar
    • English
    Volume 1 of the series Fundamentals of Medical Cell Biology is devoted to evolutionary biology. This is presented in two parts: in the first, the structure and dynamics of RNA, DNA, and protein are dealt with. The second part is concerned with the origins and cellular basis of life.

  • Isolated Hepatocytes: Preparation, Properties and Applications

    Preparation, Properties and Applications
    • 1st Edition
    • Volume 21
    • M.N. Berry + 2 more
    • R. H. Burdon
    • English
    This book sets out clearly and effectively the preparation and working methods of laboratory techniques involving isolated hepatocytes and will make life easier for every laboratory worker concerned with these techniques.

  • International Review of Cytology

    Volume 129
    • 1st Edition
    • English

  • Vectorial Transport of Proteins into and across Membranes

    • 1st Edition
    • Volume 34
    • English
    This is the third volume in this series covering protein translocation within and between cells. Volumes 31 and 32, Vesicular Transport, Parts A and B, treated techniques for eukaryotic cells available as of 1989. Vectorial Transport of Proteins into and across Membranes, brings together new methods and new topics as of 1991. Highlights include use of anti-idiotype antibodies, gene fusions, transcription, crosslinking, pulse-labeling, and reconstitution.

  • International Review of Cytology

    Volume 128
    • 1st Edition
    • English

  • International Review of Cytology

    Volume 127
    • 1st Edition
    • English

  • Protein Phosphorylation, Part B

    Analysis of Protein Phosphorylation, Protein Kinase Inhibitors, and Protein Phosphatases
    • 1st Edition
    • Volume 201
    • John N. Abelson + 1 more
    • English
    This volume provides a compilation of recent methods for studying protein phosphorylation.

  • Advances in Space Biology and Medicine

    • 1st Edition
    • Volume 1
    • S.L. Bonting
    • English
    This first volume has contributions from the United States (4), the USSR (2), Europe (2), and Japan (1). They include studies of a fundamental biological problem aided by some space experiments, investigations of biological problems encountered in spaceflight, use of microgravity for a biotechnological purpose, and technical facilities developed for animal and cell research in space. Topics include: the effects of long-term space missions on the human body (Grigoriev, USSR); skeletal responses to microgravity (Morey-Holton an Arnaud, United States); gravity effects on animal reproduction, developments, and ageing (Miquel and Souza, Spain/United States); neurovestibular physiology in fish (Watanabe, Takabayashi, Tanaka, and Yanagihara, Japan); gravity perception and circulation in plants (Brown, United States); development of higher plants under altered gravitational conditions (Merkys and Laurniavcius, Lithunaia, USSR); gravity effects on single cells (Cogoli and Gmunder, Switzerland); protein crystal growth in space (Bonting, Kishiyama, and Arno, United States).

  • Protein Phosphorylation, Part A

    Protein Kinases: Assays, Purification, Antibodies, Functional Analysis, Cloning, and Expression
    • 1st Edition
    • Volume 200
    • John N. Abelson + 1 more
    • English
    This volume provides a compilation of recent methods for studying protein phosphorylation.

  • Advances in Protein Chemistry

    • 1st Edition
    • Volume 41
    • English
    Volume 41 in a series intended for biochemists, molecular biologists, cell biologists, and biophysicists.

  • Peptide Growth Factors, Part C

    • 1st Edition
    • Volume 198
    • John N. Abelson + 1 more
    • English
    This volume includes sections dealing with specific growth factors in which new, updated, or alternative procedures are presented for purification, bioassay, radiolabeling and radioreceptor assay, immunoassay, receptor identification, and quantification and includes general techniques for the study of growth factors. For those unfamiliar with a particular area such as the oncogene-growth factor relationship orientation chapters have been included.

  • International Review of Cytology

    Volume 126
    • 1st Edition
    • English

  • Chromosome Engineering in Plants

    Genetics, Breeding, Evolution
    • 1st Edition
    • Volume 2A
    • P.K. Gupta + 1 more
    • English
    This two-volume work surveys the entire range of general aspects of chromosome research on plants. This first volume is divided into two sections. Section A consists of 11 chapters covering the entire range of general aspects of chromosome research in plants (including a chapter on genetic engineering in crop improvement). Section B is devoted to cytogenetics of cereals and millets (wheat, rye, barley, triticale, oats, maize, rice, pearl millet, and minor millets). More than one chapter is devoted to the same crop to give a detailed treatment of chromosome research (including molecular biology) in these crops.The second volume deals with cytogenetics of plant materials including legumes, vegetable and oil crops, sugar crops, forage crops, fibre crops, medicinal crops and ornamentals. This work will be useful both as a reference work and a teaching aid to satisfy a wide range of workers. Every chapter has been written by an expert who has been involved in chromosome research on a particular plant material for many years.

  • International Review of Cytology

    Volume 125
    • 1st Edition
    • English

  • Molecular Medicine

    Genomics to Personalized Healthcare
    • 3rd Edition
    • R.J. Trent
    • English
    Molecular medicine is the application of gene or DNA based knowledge to the modern practice of medicine. This book provides contemporary insights into how the genetic revolution is influencing medical thinking and practice on a broad front including clinical medicine, innovative therapies and forensic medicine.

  • Molecular Motors and the Cytoskeleton

    • 1st Edition
    • Volume 196
    • John N. Abelson + 1 more
    • English
    This volume attempts to describe the purification and assay of the diverse group of proteins involved in otoplasmic organization. Some of the more promising attempts to apply techniques of molecular biology, genetics, and molecular cytochemistry to these proteins are discussed.

  • Microbial Enhancement of Oil Recovery - Recent Advances

    • 1st Edition
    • Volume 31
    • E.C. Donaldson
    • English
    This conference was instituted to examine field activities in Microbial Enhancement of Oil Recovery. The U.S. Department of Energy has sponsored several field projects and the details from some of these were presented, as well as a few from industry. The balance of the program was concerned with new developments in research.Today's oil production technology leaves one third to one half of the original oil in place in the reservoir at abandonment of secondary recovery (waterflooding). This leaves a very large target for microbial enhanced oil recovery which was shown by the research papers of this conference to be capable of producing up to 50% of the residual oil. The field trials show that the normal projected oil production decline curve can be reversed, or leveled off by microbial enhancement of oil recovery.This conference has shown that a variety of applications are possible to correct oilfield problems as well as to enhance oil recovery. Among these is the suppression of hydrogen sulfide production which alone is a tremendous advance because of the large quantity of sour oil production. If hydrogen sulfide production can be curtailed it would increase the value of the produced oil, decrease it toxicity, and largely decrease it corrosiveness. All of these would be welcome both in the field and at the petroleum refinery where special precautions must be taken to process sour crude oil.Another very important discovery is the ability of certain bacteria to eliminate paraffin deposition around the producing well and in the tubulars. This is a welcome improvement for many producers who have considerable difficulty in controlling paraffin deposition.

  • Advances in Cancer Research

    • 1st Edition
    • Volume 56
    • English

  • Phospholipases

    • 1st Edition
    • Volume 197
    • John N. Abelson + 1 more
    • English
    This volume on Phospholipases, the first of its kind, presents techniques for the assay, purification, and characterization of these enzymes, which are not only degradative enzymes of lipid metabolism but are also key enzymes in the signal transduction pathway.

  • International Review of Cytology

    Volume 124
    • 1st Edition
    • English

  • Bacterial Growth and Division

    Biochemistry and Regulation of Prokaryotic and Eukaryotic Division Cycles
    • 1st Edition
    • Stephen Cooper
    • English
    How does a bacterial cell grow during the division cycle? This question is answered by the codeveloper of the Cooper-Helmstetter model of DNA replication. In a unique analysis of the bacterial division cycle, Cooper considers the major cell categories (cytoplasm, DNA, and cell surface) and presents a lucid description of bacterial growth during the division cycle. The concepts of bacterial physiology from Ole Maaløe's Copenhagen school are presented throughout the book and are applied to such topics as the origin of variability, the pattern of DNA segregation, and the principles underlying growth transitions. The results of research on E. coli are used to explain the division cycles of Caulobacter, Bacilli, Streptococci, and eukaryotes. Insightful reanalysis highlights significant similarities between these cells and E.coli. With over 25 years of experience in the study of the bacterial division cycle, Cooper has synthesized his ideas and research into an exciting presentation. He manages to write a comprehensive volume that will be of great interest to microbiologists, cell physiologists, cell and molecular biologists, researchers in cell-cycle studies, and mathematicians and engineering scientists interested in modeling cell growth.

  • Biomembranes, Part V: Cellular and Subcellular Transport: Epithelial Cells

    • 1st Edition
    • Volume 191
    • John N. Abelson + 1 more
    • English
    The transport volumes of the Biomembranes series were initiated with Volumes 125 and 126 of Methods in Enzymology, which covered Transport in Bacteria, Mitochondria, and Chloroplasts. Volumes 156 and 157 continued the theme with ATP-Driven Pumps and Related Transport. Cellular and Subcellular Transport: Eukaryotic (Nonepithelial) Cells was the topic of Volumes 173 and 174. The theme of this volume, as well as of Volume 192, is Cellular and Subcellular Transport: Epithelial Cells.

  • Advances in Physical Organic Chemistry

    • 1st Edition
    • Volume 26
    • English
    This series, established by Victor Gold in 1963, presents substantial and authoritative reviews of areas of chemistry in which quantitative methods are used in the study of the structures of organic compounds and their relation to physical and chemical properties.****Physi... organic chemistry is viewed as a particular approach to scientific inquiry rather than a further intellectual specialization. Organometallic compounds are included, and relevant aspects of physical, theoretical, inorganic, and biological chemistry are incorporated in reviews where appropriate.

  • Adenylyl Cyclase, G Proteins, and Guanylyl Cyclase

    • 1st Edition
    • Volume 195
    • John N. Abelson + 1 more
    • English
    This volume emphasizes methods for the assay, purification, and characterization of adenylyl cyclases, guanine nucleotide-dependent regulatory proteins (G proteins), and guanylyl cyclases.

  • Biomembranes, Part W: Cellular and Subcellular Transport: Epithelial Cells

    • 1st Edition
    • Volume 192
    • John N. Abelson + 1 more
    • English
    The transport volumes of the Biomembranes series were initiated with Volumes 125 and 126 of Methods in Enzymology, which covered Transport in Bacteria, Mitochondria, and Chloroplasts. Volumes 156 and 157 continued the theme with ATP-Driven Pumps and Related Transport. Cellular and Subcellular Transport: Eukaryotic (Nonepithelial) Cells was the topic of Volumes 173 and 174. The theme of this volume, as well as of Volume 192, is Cellular and Subcellular Transport: Epithelial Cells.

  • Mass Spectrometry

    • 1st Edition
    • Volume 193
    • John N. Abelson + 1 more
    • English
    This volume presents a compilation of experimental methods and principles, with detailed protocols and examples. Techniques which have demonstrated value in problem-solving are included.Intended for biochemists, cell biologists, microbiologists, pharmacologists, biomedical scientists, biophysicists, analytical chemists, and physiologists, this book focuses on mass spectrometry. Topics discussed include the methods of ionization, liquid chromatography, continuous flow fast atom bombardment mass spectrometry, collision-induced dissociation, enzymatic and chemical digestion of proteins, and constituents of nucleic acids. Other titles in this series include Guide to Yeast Genetics and Molecular Biology and Retinoids, Part B: Cell Differentiation and Clinical Applications.

  • Retinoids, Part B

    Cell Differentiation and Clinical Applications
    • 1st Edition
    • Volume 190
    • John N. Abelson + 1 more
    • English
    The methods in Volumes 189 and 190 apply to the use of retinoids in basic research in molecular, cellular, and development biology and in clinical medicine.

  • International Review of Cytology

    Volume 123
    • 1st Edition
    • English

  • Mechanisms of Catalysis

    • 3rd Edition
    • Volume 19
    • English
    The remarkable expansion of information leading to a deeper understanding of enzymes on the molecular level necessitated the development of this volume which not only introduces new topics to The Enzymes series but presents new information on some covered in Volume I and II of this edition.

  • Flow Cytometry

    • 1st Edition
    • Volume 33
    • English

  • Retinoids, Part A

    Molecular and Metabolic Aspects
    • 1st Edition
    • Volume 189
    • John N. Abelson + 1 more
    • English
    The methods in Volumes 189 and 190 apply to the use of retinoids in basic research in molecular, cellular, and development biology and in clinical medicine.

  • Visual Fields

    Clinical Case Presentations
    • 1st Edition
    • John C. Townsend + 2 more
    • English

  • Taking Software Design Seriously

    Practical Techniques for Human–Computer Interaction Design
    • 1st Edition
    • John Karat
    • English

  • Avian Incubation

    Poultry Science Symposium Number Twenty-Two
    • 1st Edition
    • S. G. Tullett
    • English

  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1st Edition
    • Volume 48
    • English
    Intended for researchers in biochemistry, medicine, nutrition and industry, this book discusses such topics as components of bacterial polysaccharides, fluorinated carbohydrates, and carbon sugars chemistry.

  • Cumulative Subject Index, Volumes 135-139, 141-167

    • 1st Edition
    • Volume 175
    • English
    The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.

  • Advances in Genetics

    • 1st Edition
    • Volume 28
    • English

  • International Review of Cytology

    Volume 122
    • 1st Edition
    • English

  • Cell Culture for Biochemists

    • 2nd Edition
    • Volume 8
    • R.L.P. Adams
    • English
    This 2nd revised edition equals the popular 1st edition in providing a clear and detailed overview of cell culture. It presents information on: characteristics of cultured cells; culture vessels; glassware preparation and sterilisation techniques; subculturing; primary cells; cell culture media; techniques; contamination; the cell cycle; cell synchronisation; use of radioactive isotopes in cell culture; cell mutants and cell hybrids; viruses; and differentiation in cell cultures.Reviews on the 1st edition: ``.. the book provides an excellent insight into the way cell culture techniques can be employed in the analytical study of cellular biology.'' - Trends in Biochemical Sciences ``It is well written in a concise, easy-to-read style which stimulates the interest of the reader....'' - Science Tools ``A useful handbook on principles and practice.'' - Immunology Today

  • Aging and Cognition

    Knowledge Organization and Utilization
    • 1st Edition
    • Volume 71
    • T.M. Hess
    • English
    During the past two decades, there has been a dramatic increase in interest in the study of aging-related changes in cognitive abilities. In this volume researchers from a variety of theoretical perspectives discuss adult age differences in a wide range of cognitive skills. Of special interest is the extent to which aging effects on performance are related to variations in the representation, organization, and utilization of knowledge, broadly defined. Recent research and theory in the field of aging has emphasized the need to examine such processes more closely in order to provide a more complete understanding of aging effects on cognitive behavior.

  • Hydrocarbons and Methylotrophy

    • 1st Edition
    • Volume 188
    • John N. Abelson + 1 more
    • English
    This volume is the first comprehensive compilation of methods for the assay and purification of enzymes involved in the utilization of reduced one-carbon compounds and higher hydrocarbons. In the last decade there has been an explosion of interest in the organisms that grow on one-carbon compounds and in those that grow on higher hydrocarbons. This is due to the commercial interest in the unique enzymes involved in these specialty metabolic pathways and to a growing understanding of the important role these organisms play in carbon cycling in nature. More recent interest in the use of these organisms and their enzymes for detoxification of hazardous waste has once again put the spotlight on these unique microorganisms. This volume will prove to be a valuable source for researchers in academia, government, and industry alike.

  • Theory of Simple Liquids

    • 2nd Edition
    • Jean-Pierre Hansen + 1 more
    • English
    This book gives a comprehensive and up-to-date treatment of the theory of "simple" liquids. The new second edition has been rearranged and considerably expanded to give a balanced account both of basic theory and of the advances of the past decade. It presents the main ideas of modern liquid state theory in a way that is both pedagogical and self-contained. The book should be accessible to graduate students and research workers, both experimentalists and theorists, who have a good background in elementary mechanics.

  • Arachidonate Related Lipid Mediators

    • 1st Edition
    • Volume 187
    • John N. Abelson + 1 more
    • English
    This volume includes information on arachidonic acid metabolites and platelet activating factor. Assays for the quantitative measurement of prostaglandins, leukotrienes, and platelet-activating factor, including enzyme immunoassays and mass spectrophotometric techniques, are presented. Preparation and analysis of cytochrome P-450 metabolites of arachidonic acid are discussed. The isolation, purification, and assay of enzymes important in the biosynthesis and metabolism of these lipids are included.

  • Oxygen Radicals in Biological Systems, Part B

    Oxygen Radicals and Antioxidants
    • 1st Edition
    • Volume 186
    • John N. Abelson + 1 more
    • English
    The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.

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