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Molecular Medicine

Genomics to Personalized Healthcare

Molecular medicine is the application of gene or DNA based knowledge to the modern practice of medicine. This book provides contemporary insights into how the genetic revolution is… Read more

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Description

Molecular medicine is the application of gene or DNA based knowledge to the modern practice of medicine. This book provides contemporary insights into how the genetic revolution is influencing medical thinking and practice on a broad front including clinical medicine, innovative therapies and forensic medicine.

Key features

  • Extensively revised just after the completion of the Human Genome Project, it provides the latest in molecular medicine developments
  • The only book in Molecular Medicine that has undergone three editions
  • Current practice as well as future developments identified
  • Extensive tables, well presented figures - resources for further understanding

Readership

Graduate students/postgraduates, clinicians in molecular biology and genetics

Table of contents

Chapter 1: HISTORY OF MOLECULAR MEDICINE

  • Publisher Summary
  • THE FOUNDATIONS: 1869–1980s
  • Modern ERA: 1980s–2000s
  • Human Genome Project: 1990–2000
  • FUTURE

Chapter 2: DNA, RNA, GENES AND CHROMOSOMES

  • Publisher Summary
  • DNA
  • RNA
  • GENE STRUCTURE
  • POLYMERASE CHAIN REACTION (PCR)
  • CHROMOSOMES
  • DNA MUTATIONS AND POLYMORPHISMS
  • DNA TESTS
  • FUTURE

Chapter 3: MENDELIAN GENETIC TRAITS

  • Publisher Summary
  • INTRODUCTION
  • AUTOSOMAL DOMINANT DISORDERS
  • AUTOSOMAL RECESSIVE DISORDERS
  • X-LINKED DISORDERS
  • FUTURE

Chapter 4: COMPLEX GENETIC TRAITS

  • Publisher Summary
  • INTRODUCTION
  • MULTIFACTORIAL DISORDERS
  • NOVEL MECHANISMS FOR DNA AND DISEASE
  • ONCOGENESIS
  • SOMATIC CELL GENETICS
  • FUTURE

Chapter 5: GENOMICS, PROTEOMICS AND BIOINFORMATICS

  • Publisher Summary
  • INTRODUCTION
  • GENOMICS
  • PROTEOMICS
  • BIOINFORMATICS
  • FUTURE

Chapter 6: GENETIC AND CELLULAR THERAPIES

  • Publisher Summary
  • RECOMBINANT DNA–DERIVED DRUGS
  • CELLULAR THERAPIES
  • FUTURE

Chapter 7: REPRODUCTION AND DEVELOPMENT

  • Publisher Summary
  • REPRODUCTION
  • DEVELOPMENT
  • PRENATAL DIAGNOSIS
  • NEWBORN SCREENING
  • FUTURE

Chapter 8: INFECTIOUS DISEASES

  • Publisher Summary
  • DIAGNOSTICS
  • PATHOGENESIS
  • EPIDEMIOLOGY
  • EMERGING INFECTIONS
  • FUTURE

Chapter 9: FORENSIC MEDICINE AND SCIENCE

  • Publisher Summary
  • HISTORICAL DEVELOPMENTS
  • REPETITIVE DNA
  • FORENSIC ANALYSIS
  • HUMAN RELATIONSHIPS
  • TISSUE IDENTIFICATION
  • TERRORISM
  • FUTURE

Chapter 10: ETHICAL, LEGAL AND SOCIAL IMPLICATIONS

  • Publisher Summary
  • INTRODUCTION
  • DNA TESTING
  • RESEARCH
  • GENETIC AND CELLULAR THERAPIES
  • GOVERNMENT
  • FUTURE

Review quotes

"...represents an important contribution to the scientific audience as it separates the knowledge of molecular biology and defines it in molecular medicine terms. The book provides a different and unique perspective to the definition and implications of DNA in medicine. This is a high quality book with excellent art work that contributes significantly to the understanding of the text. As the field of molecular medicine expands, it is clear that textbooks such as this will continue to be needed."—DOODY'S - 3 Stars(2005)

"The text, with its thorough multidisciplinary and interdisciplinary perspectives, provides an excellent resource for students and professionals working in microbiology, biochemisty, genetics, infectious diseases, molecular biology, and related fields."—CLINICAL INFECTIOUS DISEASES (January 2005)

"The third edition is a compact primer of molecular medicine that should be very useful to the student or scientist...College and medical students, medical scientists and physicians, and scientists working in other fields who are interested in understanding the principles and methods of molecular medicine will find this a useful and compact introductory reference."—Marshall Lichtman, University of Rochester Medical Center (2005)

Product details

About the author

RT

R.J. Trent

Affiliations and expertise
Professor of Medical Molecular Genetics, Sydney Medical School, University of Sydney, Australia.

View book on ScienceDirect

Read Molecular Medicine on ScienceDirect