Molecular Medicine
Genomics to Personalized Healthcare
- 4th Edition - October 30, 2018
- Author: R.J. Trent
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 3 8 1 4 5 1 - 7
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 1 0 0 7 2 - 1
- eBook ISBN:9 7 8 - 0 - 1 2 - 3 8 1 4 5 2 - 4
Molecular Medicine is the application of genetic or DNA-based knowledge to the modern practice of medicine. Molecular Medicine, 4e, provides contemporary insights into how the ge… Read more
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Molecular Medicine is the application of genetic or DNA-based knowledge to the modern practice of medicine. Molecular Medicine, 4e, provides contemporary insights into how the genetic revolution is influencing medical thinking and practice. The new edition includes recent changes in personalized medicine, new growth in omics and direct-to-consumer DNA testing, while focusing on advances in the Human Genome project and implications of the advances in clinical medicine. Graduate students, researchers, clinicians and allied health professionals will appreciate the background history and clinical application of up-to-date molecular advances.
- Extensively revised to incorporate the results of the Human Genome Project, it provides the latest developments in molecular medicine
- The only book in Molecular Medicine to reach its fourth edition
- Identifies current practice as well as future developments
- Presents extensive tables, well presented figures and resources for further understanding
Graduate students/postgraduates, clinicians in molecular biology and genetics
Acknowledgments and Dedications
Preface
Chapter 1. Genes to Personalized Medicine
Introduction
Genome Anatomy
Human Genome Project
Genome Variation
Personalized Medicine
References
Chapter 2. Genes, Environment and Inheritance
Introduction
Mendelian Genetic Inheritance
Other Forms of Genetic Inheritance
Complex Genetic Inheritance
Epigenetic Inheritance
Somatic Cell Genetics
References
Chapter 3. DNA Genetic Testing
Introduction
DNA Variants
Detecting DNA Variants
Calculating Risk
DNA Genetic Tests
Evaluation
Challenges
References
Chapter 4. Omics
Introduction
DNA Sequencing
DNA Microarrays
Bioinformatics
Other Omics
Systems Biology
Overview
References
Chapter 5. Delivering Genetics and Genomics Direct-to-Consumer
Introduction
Pros and Cons
Ways Forward
References
Chapter 6. Public Health, Communicable Diseases and Global Health
Public Health
Communicable Diseases
Global Health
References
Chapter 7. Development, Aging and Cancer
Development
Aging
Oncogenesis
Germline Cancers
Somatic Cell Cancers
References
Chapter 8. Molecular and Cellular Therapies
Introduction
Recombinant DNA Products
Gene Transfer
Regenerative Medicine
Other Therapies
References
Chapter 9. Forensic Science and Medicine
Introduction
DNA Profiling
Bioterror
Future
References
Chapter 10. Ethical, Legal and Social Issues (ELSI)
Introduction
Consent
DNA Genetic Tests
Oversight
Challenges Ahead
References
Index
- Edition: 4
- Published: October 30, 2018
- Language: English
RT
R.J. Trent
Affiliations and expertise
Professor of Medical Molecular Genetics, Sydney Medical School, University of Sydney, Australia.Read Molecular Medicine on ScienceDirect