Books in Molecular biology cellular biology and genetics

Thematic Approaches to COVID-19

1st Edition
June 1, 2024
Rajkumar Rajendram + 3 more
English
Hardback
9 7 8 0 4 4 3 1 8 8 3 1 2

Features, Transmission, Detection, and Case Studies in COVID-19 examines the effects of the virus on the body, as well as its transmission and clinical profile. This volume begins with an introduction to the virus and its pathogenesis, transmission, and avoidance, followed by sections on pulmonary and cardiovascular effects, obesity, diabetes, the liver, detection issues, and biomarkers. Vaccines and treatment are also discussed. Specific case studies covered include hypoxia, acute kidney injury, pneumonia, and neurological effects. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.Linking Neuroscience and Behavior in COVID-19 examines the effect of both the virus and the pandemic on behavior and mental health. Chapters look at the burden of the COVID-19 pandemic on those with pre-existing conditions, including Parkinson's disease and multiple sclerosis. The ongoing consequences of the pandemic on the mental health of the broad populace are discussed. As well as the neurological effects of the virus itself, chapters discuss psychological concerns including depression and anxiety. Finally, the chapters also include aspects relevant to managing care and the treatment of conditions. A broad range of conditions preceding, caused by, or emerging for the first time during the pandemic are also detailed.Internation... and Life Course Aspects of COVID-19 describes the nuances and international variations of COVID-19 in different populations and age groups. This volume details those differences in chapters examining the effects of the virus at different life stages, including newborns, children, adolescents, and older populations. Consideration of the age-specific effects of COVID-19 on the brain are a major focus unique to this resource. International observations and global outcomes are also described. This volume is relevant for all clinicians working to ensure the best outcomes for patients with COVID-19 worldwide.Management... Body Systems, and Case Studies in COVID-19 describes the assessment and treatment of patients infected with the novel coronavirus that causes the varied symptoms of COVID-19. Detailing this multisystem disease and the organs and tissues affected, this volume features chapters on several body systems. Conditions affecting the respiratory, hematological, hepatobiliary, renal, gastrointestinal, nervous, musculoskeletal, and cardiovascular systems are addressed. The fundamental role of telemedicine during the pandemic is also discussed. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.

Tryptamine Microbiota-Deregulated Aminoacyl-tRNA Biosynthesis

1st Edition
May 31, 2024
Elena L. Paley
English
Paperback
9 7 8 0 4 4 3 2 8 8 3 0 2
eBook
9 7 8 0 4 4 3 2 8 8 3 1 9

Tryptamine Microbiota-Deregulat... Aminoacyl-tRNA Biosynthesis: A Conceptual Evolution of the Role of Microbiota Tryptamine in Human Diseases provides a detailed investigation into tryptamine, its underlying mechanisms, and metabolism across multiple diseases. The book explores key concepts of tryptamine, its biosynthetic pathways, and its influence in disease, specifically focusing on the Alzheimer’s disease-associated gut bacterial sequence (ADAS). Various neurodegenerative conditions are covered alongside cancer, diabetes, infections, and chromosomal aberrations. Additionally, a chapter on gut tryptamine in domestic and agricultural animals is included. The book closes with case studies involving FDG-PET imaging in the context of tryptamine-treated mouse models and Alzheimer’s disease patients.This book elucidates the implications of the gut microbiota-mediated tryptamine metabolism for human health, sharing insights into disease etiology, mechanisms, testing, prevention, and treatment. It is an ideal reference for researchers across the biomedical sciences.

Digital Healthcare in Asia and Gulf Region for Healthy Aging and More Inclusive Societies

1st Edition
May 24, 2024
Patricia Ordonez de Pablos
English
Paperback
9 7 8 0 4 4 3 2 3 6 3 7 2
eBook
9 7 8 0 4 4 3 2 3 6 3 8 9

Digital Healthcare in Asia and Gulf Region for Healthy Aging and More Inclusive Societies: Shaping Digital Future provides insight to the potential of advanced information technologies to build stronger healthcare systems, better quality healthcare services, and more resilient societies. The book covers two important regions: Gulf Region (Bahrein, Kuwait, Oman, Qatar, and UAE) and Asia, and explores how these countries develop policies for healthy aging and how digital tools can serve these goals. This book delivers a collection of relevant, innovative research works on digital healthcare, with four main goals: (1) to cover two geographical regions (Asia and Gulf Region) with important advances in digital healthcare; (2) to present case studies in the field of IT and digital health during the pandemic and analyze the lessons from these studies; (3) to evaluate the latest advances in the field of digital healthcare (especially Artificial Intelligence [AI], Big Data, Blockchain, and 5G); and (4) to discuss implications for main stakeholders (patients, doctors, IT experts, directors, and policy managers) and recommendations for policy makers in these two regions and elsewhere.

Targeting Signaling Pathways in Solid Tumors Part B

1st Edition
Volume 386
May 23, 2024
Sumit Mukherjee + 1 more
English
Hardback
9 7 8 0 4 4 3 2 3 5 4 8 1
eBook
9 7 8 0 4 4 3 2 3 5 4 9 8

Targetting Signaling Pathways in Solid tumour Part B, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Biological Insights of Multi-Omics Technologies in Human Diseases

1st Edition
May 23, 2024
Aarif Ali + 3 more
English
Paperback
9 7 8 0 4 4 3 2 3 9 7 1 7
eBook
9 7 8 0 4 4 3 2 3 9 7 0 0

Biological Insights of Multi-Omics Technologies in Human Diseases provides detailed information about the basics of multi-omic technologies, including ethics, historical perspective, science, drug discovery, and development and metabolism. With a strong focus on the practical application of omics approaches in cancer, cardiovascular, neurology, respiratory, viral, gastroenterology, autoimmune diseases, PCOS and tuberculosis, this book also includes special topics related to COVID-19 and Machine learning approaches. In 13 chapters, this book provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of multi-omics from academic, regulatory, pharmaceutical, socio-ethical, and economic perspectives.The chapters are designed in a well-defined chronology such that readers will intuitively understand the central idea. This book is an ideal resource for health professionals, scientists and researchers, nutritionists, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

Phylogenomics

1st Edition
May 17, 2024
Igor Mokrousov + 1 more
English
Paperback
9 7 8 0 3 2 3 9 9 8 8 6 4
eBook
9 7 8 0 3 2 3 9 1 3 0 9 6

Phylogenomics: Foundations, Methods, and Pathogen Analysis offers a deep overview of phylogenomics as a field, compelling recent developments, and detailed methods and approaches for conducting new research. Early chapters introduce phylogenomic analysis of viruses and bacteria, deciphering bacterial outbreaks, and evolution of drug resistance and virulence, with a second section on methods offering instruction in tools for SNP calling and dealing with big datasets, use of Bayesian approach in molecular epidemiology, bacterial evolution modeling and evolutionary reconstruction in the presence of mosaic sequences. Part 3 offers various examples of phylogenomic analysis across medically significant bacteria and viruses, including Yersinia pestis, Salmonella, Mycobacterium tuberculosis, HIV-1, measles virus as well as ancient pathogens research.

Integrative Omics

1st Edition
May 3, 2024
Manish Kumar Gupta + 3 more
English
Paperback
9 7 8 0 4 4 3 1 6 0 9 2 9
eBook
9 7 8 0 4 4 3 1 6 0 9 3 6

Integrative Omics: Concept, Methodology and Application provides a holistic and integrated view of defining and applying network approaches, integrative tools, and methods to solve problems for the rationalization of genotype to phenotype relationships. The reference provides systemic ‘step-by-step’ coverage that begins with basic concepts from Omic to Multi Integrative Omics approaches followed by applications and emerging and future trends. All areas of Omics are covered, including biological databases, sequence alignment, pharmacogenomics, nutrigenomics and microbial omics, integrated omics for Food Science and Identification of genes associated with disease, clinical data integration and data warehousing, translational omics, technology policy, and society research. This book covers recent concepts, methodologies, advancements in technologies and is also well-suited for researchers from both academic and industry background, undergraduate and graduate students who are mainly working in the area of computational systems biology, integrative omics and translational science.

Clinical Genomics

2nd Edition
May 1, 2024
Shashikant Kulkarni + 1 more
English
Paperback
9 7 8 0 3 2 3 9 0 0 2 4 9

Clinical Genomics: A Guide to Clinical Next Generation Sequencing, Second Edition provides a full overview of next-generation sequencing (NGS) technologies that are currently used in clinical diagnostic laboratories. The book presents key bioinformatic challenges and solutions that must be addressed by clinical genomicists and genomic pathologists, such as specific pipelines for identification of the full range of variants that are clinically important. It focuses on the challenges of diagnostic interpretation of NGS results in a clinical setting, with later sections devoted to emerging regulatory issues governing the clinical use of NGS and reimbursement paradigms that will affect the way in which laboratory professionals get compensated for testing.Following the wide use of the current edition by clinicians and researchers alike, this fully revised, new edition addresses the evolving landscape of genomics medicine, along with recent advances in our understanding of molecular mechanisms of human diseases and developmental biology. In addition, the book updates on sequencing chemistry and platforms, bioinformatics algorithms, clinical informatics, IT infrastructure and emerging applications of artificial intelligence in genomics.

Correlative Light and Electron Microscopy V

1st Edition
Volume 187
April 30, 2024
Thomas Müller-Reichert + 1 more
English
Hardback
9 7 8 0 3 2 3 9 5 1 4 1 8
eBook
9 7 8 0 3 2 3 9 5 1 4 2 5

Correlative Light and Electron Microscopy V, Volume 187 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Orthotopic brain tumor models derived from glioblastoma stem-like cells, RNA sequencing in hematopoietic stem cells, Generation of inducible pluripotent stem cells from human dermal fibroblasts, In vitro preparation of dental pulp stem cell grafts combined with biocompatible scaffolds for tissue engineering, Gene expression knockdown in chronic myeloid leukemia stem cells, Identification and isolation of slow-cycling GSCs, Assessment of CD133, EpCAM, and much more.

Applications of Metagenomics

1st Edition
April 23, 2024
Hrudayanath Thatoi + 2 more
English
Paperback
9 7 8 0 3 2 3 9 8 3 9 4 5
eBook
9 7 8 0 3 2 3 9 8 4 0 3 4

Applications of Metagenomics: Agriculture, Environment, and Health examines current metagenomics methods and their applications in soil, polluted environment sites, agriculture production, and health care, with separate sections dedicated to each application area. Special attention is paid to the biotechnological study of novel microbial resources for social welfare. Beyond applications, the book discusses evolving next generation technology and techniques used for carrying out metagenomics studies, and in doing so highlights the latest research and advances in the field, along with ways to adapt these approaches for different study types across the biological sciences.Chapter topics range from metagenomics for studying root microbial communities to microbial diversity of the rhizosphere, fungal diversity, microbial biodiversity in forest environments, the human microbiome, and disease epidemiology, with one chapter dedicated to Covid-19 metagenomics.

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