Thematic Approaches to COVID-19
- 1st Edition - June 1, 2024
- Latest edition
- Editors: Rajkumar Rajendram, Victor R. Preedy, Vinood Patel, Colin R. Martin
- Language: English
Features, Transmission, Detection, and Case Studies in COVID-19 examines the effects of the virus on the body, as well as its transmission and clinical profile. This volume begins… Read more
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Description
Description
Features, Transmission, Detection, and Case Studies in COVID-19 examines the effects of the virus on the body, as well as its transmission and clinical profile. This volume begins with an introduction to the virus and its pathogenesis, transmission, and avoidance, followed by sections on pulmonary and cardiovascular effects, obesity, diabetes, the liver, detection issues, and biomarkers. Vaccines and treatment are also discussed. Specific case studies covered include hypoxia, acute kidney injury, pneumonia, and neurological effects. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.
Linking Neuroscience and Behavior in COVID-19 examines the effect of both the virus and the pandemic on behavior and mental health. Chapters look at the burden of the COVID-19 pandemic on those with pre-existing conditions, including Parkinson's disease and multiple sclerosis. The ongoing consequences of the pandemic on the mental health of the broad populace are discussed. As well as the neurological effects of the virus itself, chapters discuss psychological concerns including depression and anxiety. Finally, the chapters also include aspects relevant to managing care and the treatment of conditions. A broad range of conditions preceding, caused by, or emerging for the first time during the pandemic are also detailed.
International and Life Course Aspects of COVID-19 describes the nuances and international variations of COVID-19 in different populations and age groups. This volume details those differences in chapters examining the effects of the virus at different life stages, including newborns, children, adolescents, and older populations. Consideration of the age-specific effects of COVID-19 on the brain are a major focus unique to this resource. International observations and global outcomes are also described. This volume is relevant for all clinicians working to ensure the best outcomes for patients with COVID-19 worldwide.
Management, Body Systems, and Case Studies in COVID-19 describes the assessment and treatment of patients infected with the novel coronavirus that causes the varied symptoms of COVID-19. Detailing this multisystem disease and the organs and tissues affected, this volume features chapters on several body systems. Conditions affecting the respiratory, hematological, hepatobiliary, renal, gastrointestinal, nervous, musculoskeletal, and cardiovascular systems are addressed. The fundamental role of telemedicine during the pandemic is also discussed. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.
Linking Neuroscience and Behavior in COVID-19 examines the effect of both the virus and the pandemic on behavior and mental health. Chapters look at the burden of the COVID-19 pandemic on those with pre-existing conditions, including Parkinson's disease and multiple sclerosis. The ongoing consequences of the pandemic on the mental health of the broad populace are discussed. As well as the neurological effects of the virus itself, chapters discuss psychological concerns including depression and anxiety. Finally, the chapters also include aspects relevant to managing care and the treatment of conditions. A broad range of conditions preceding, caused by, or emerging for the first time during the pandemic are also detailed.
International and Life Course Aspects of COVID-19 describes the nuances and international variations of COVID-19 in different populations and age groups. This volume details those differences in chapters examining the effects of the virus at different life stages, including newborns, children, adolescents, and older populations. Consideration of the age-specific effects of COVID-19 on the brain are a major focus unique to this resource. International observations and global outcomes are also described. This volume is relevant for all clinicians working to ensure the best outcomes for patients with COVID-19 worldwide.
Management, Body Systems, and Case Studies in COVID-19 describes the assessment and treatment of patients infected with the novel coronavirus that causes the varied symptoms of COVID-19. Detailing this multisystem disease and the organs and tissues affected, this volume features chapters on several body systems. Conditions affecting the respiratory, hematological, hepatobiliary, renal, gastrointestinal, nervous, musculoskeletal, and cardiovascular systems are addressed. The fundamental role of telemedicine during the pandemic is also discussed. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.
Key features
Key features
Features, Transmission, Detection, and Case Studies in COVID-19
- Discusses COVID-19 biology, including pathogenesis and transmission
- Describes systemic issues caused by COVID-19, including cardiovascular effects and loss of taste and smell
- Outlines detection methods, biomarkers associated with severity, and disease outcomes
- Features individual chapter introductions, summaries, and case studies to provide comprehensive descriptions of COVID-19 symptoms and effects
- Contains chapters with key facts, dictionary of terms, summary points, applications to other areas pertinent to each chapter, and policies and procedures
- Discusses COVID-19 biology, including pathogenesis and transmission
- Describes systemic issues caused by COVID-19, including cardiovascular effects and loss of taste and smell
- Outlines detection methods, biomarkers associated with severity, and disease outcomes
- Features individual chapter introductions, summaries, and case studies to provide comprehensive descriptions of COVID-19 symptoms and effects
- Contains chapters with key facts, dictionary of terms, summary points, applications to other areas pertinent to each chapter, and policies and procedures
- Discusses the impact of the COVID-19 pandemic and the virus itself on behavior and psychology
- Examines comorbidities including Parkinson's disease, neuroinflammation, and autism spectrum disorders
- Outlines the management and care for coexisting conditions including brain tumors, multiple sclerosis, and ischemic stroke
- Features chapters on the severe damage to the nervous system which may be caused by SARS-CoV-2 infection including myelitis
- Contains chapters with key facts, dictionary of terms, summary points, applications to other areas pertinent to each chapter, and policies and procedures
- Examines COVID-19 symptoms and concerns according to age
- Discusses outcomes related to global populations and differences observed in symptomatology and care
- Focuses on the brain, with a look at developmental changes in pregnancy, newborns, childhood, and adolescence
- Describes mental health impacts in the older populations
- Features individual chapter introductions and summaries to provide a comprehensive introduction
- Contains chapters with key facts, dictionary of terms, summary points, applications to other areas pertinent to each chapter, and policies and procedures
- Discusses the management of multisystem symptomatology, including the effects of COVID-19 on the neurological, respiratory, hematological, hepatobiliary, gastrointestinal, and cardiovascular systems
- Includes select guidelines for clinics providing care for COVID-19 patients
- Features individual chapter introductions, and a section on case studies to provide a comprehensive primer for each topic
- Contains chapters with key facts, dictionary of terms, summary points, applications to other areas pertinent to each chapter, and policies and procedures
Readership
Readership
Neuroscientists, neurologists, clinicians, health scientists, public health workers, doctors, and research scientists. Also relevant for clinicians working with haematological, hepatobiliary, gastrointestinal, and cardiovascular systems
Table of contents
Table of contents
Features, Transmission, Detection, and Case Studies in COVID-19
Preface
Section A: SARS-CoV-2 and COVID-19: Introductory chapters and setting the scene
1. Coronavirus disease 2019 (COVID-19) pandemic in context: Systemic effects
Rajkumar Rajendram, Vinood B. Patel, and Victor R. Preedy
2. Early warning of SARS-CoV-2 infection
Daniele Proverbio, Françoise Kemp, and Jorge Gonçalves
3. Mobile phones and their use to study dynamics of the COVID-19 pandemic
Alex Berke and Kent Larson
Section B: Structure, transmission and avoidance
4. Cis regulatory elements: A novel communication route between the host cell and the SARS-CoV-2 genome
Barsanjit Mazumder and Anton A. Komar
5. SARS-CoV-2 ORF8: Structure, evolution, molecular function, and its contribution to the
pathogenicity of the virus
Muhamad Fahmi, Yukihiko Kubota, and Masahiro Ito
6. SARS-CoV-2 spike protein binding ligands and its application in COVID-19 therapeutics
Westley Van Zant, Gustavo Felippe Da Silva, Maria De Lourdes Borba Magalhães, and
Partha Ray
7. SARS-CoV-2 bulldozes the autophagy pathway and unhinges mitochondrial quality control
thereby driving neurodegeneration—A hypothesis
Ben Loos and Tamryn Barron
8. The Omicron variant of SARS-CoV-2
José Luis Zambrano, Rossana C. Jaspe, Carmen L. Loureiro, Héctor R. Rangel, Ferdinando Liprandi, and Flor H. Pujol
9. Monitoring SARS-CoV-2 spread in hospitals
Vincenzo Romano Spica and Antonio Piccolella
10. Computational analysis of mutations in SARS-CoV-2 variants spike protein and protein
interactions
Eduardo U.M. Moreira, Diego C.B. Mariano, and Raquel C. de Melo-Minardi
11. Airborne transmission of SARS-CoV-2
Andrew Fox-Lewis
12. Reducing transmission of SARS-CoV-2 with face masks: Its potential protective effects
Cristiane M. Eller, Vinicius M. Mello, and Marco A.P. Horta
13. Digital twin of ventilation system against COVID-19 transmission and infection risk
Jonathan Koon Ngee Tan and Adrian Wing-Keung Law
14. Pets and SARS-CoV-2: What is their role in the epidemiology of the disease?
Sandra Barroso-Arévalo and José M. Sánchez-Vizcaíno
15. SARS-CoV-2 transmission in dental practice
Hironori Sakai, Eiji Kondo, Hirokazu Tanaka, Tetsu Shimane, Masao Hashidume, and
Hiroshi Kurita
16. SARS-CoV-2 compared with influenza and respiratory syncytial virus in terms of vertical
transmission
Sara Manti and Giovanni Piedimonte
17. Reducing droplets and aerosols in the surgical setting and applications to the COVID-19
pandemic
Belén Salvatierra-Vicario and Jaime Viera-Artiles
18. SARS-CoV motion dynamics: Linking in droplet size
Mehmet Aydin and Seckin Aydin Savas
19. Ventilation and airborne particles in classrooms: Implications for the COVID-19 pandemic
Marta F. Gabriel, Fátima Felgueiras, and Gonçalo Marques
20. Indoor transmission of the SARS-CoV-2 virus through aerosols emitted by e-cigarettes
Roberto A. Sussman
Section C: Impact and effects
21. The Impact of COVID-19 on first responders
Brian T. Montague, Larissa Pisney, and Eric A.F. Simões
22. COVID-19 and suspected drug-induced liver injury
Rolf Teschke and Axel Eickhoff
23. Pulmonary fibrosis in COVID-19
Ryosuke Imai and Naoki Nishimura
24. The effect of SARS-CoV-2 infection on cancer: Clinical correlation and
potential pathological mechanism
Trien Trey Tang, Syed Ahad Muhammad Haidry, Cade Lewis, and Yujiang Fang
25. Severe SARS-CoV-2, plateletendothelium interactions, and cardiovascular injury
Theresa M. Rossouw, Ronald Anderson, and Charles Feldman
26. Cardiometabolic syndrome and COVID-19: Pathophysiological aspects
Subo Dey, Wojciech Rzechorzek, and Wilbert Aronow
27. COVID-19 and type 1 and 2 diabetes: An overview
Vahid Reza Askari and Vafa Baradaran Rahimi
28. COVID-19 and older adults: An overview
Vahid Reza Askari and Vafa Baradaran Rahimi
29. COVID-19 and male fertility
Mohammad Reza Fadaei, Mohammad Mahdi Dabaghi, Mohammad Saleh Fadaei, Vafa Baradaran Rahimi, and Vahid Reza Askari
30. COVID-19 and obesity: An overview
Vahid Reza Askari, Matin Shirazinia, Mohammad Saleh Fadaei, and Vafa Baradaran Rahimi
Section D: Treatments, strategies, and vaccines
31. COVD-19 vaccines and their impact: An overview
Ka Wa Khong and Ivan F.N. Hung
32. Exploring the promise of COVID-19 vaccines: A review of preclinical studies
Shubham Adhikary, Harpal S. Buttar, Hardeep Singh Tuli, and Ginpreet Kaur
33. Drugs actively being investigated for use in COVID-19
Ruiqi Zhang and Ivan F.N. Hung
34. The biology of neutralizing antibody therapy with REGEN-COV
Hiroaki Sasaki
35. The intensive care unit and percutaneous tracheostomy in patients with coronavirus disease
2019
Burhan Dost and Ozgür Kömürcü
36. Cardiac effects of drugs and vaccines used to treat and prevent COVID-19
Luigi X. Cubeddu and Marylee Tailor
37. COVID-19 pandemic and isolation: Impact on sleep
Maria Beatriz Duarte Gavião, Camila Rita Vicente Marceliano, and Dora Zulema Romero Diaz
38. Strategies in the COVID-19 pandemic: Disinfection of gloved hands
Verónica V. Márquez-Hernández, Lorena Gutiérrez-Puertas, Alba García-Viola, José Miguel Garrido-Molina, Alfredo Alcayde-García, and Gabriel Aguilera-Manrique
39. In silico studies on established antivirals on SARS-CoV-2 RNAdependent RNA polymerase
Ismail Celik, Meryem Erol, and Trina Ekawati Tallei
40. The COVID-19 cytokine storm and its immunomodulatory treatment
Maha Mohamed Saber-Ayad, Iman Mamdouh Talaat, Rakhee Kizhuvappat Ramakrishnan, and Nada
Mahmoud Soliman Yakout
41. Safety and efficacy of nebulization for reducing the intensity of viral load and clinical manifestations in patients with COVID-19
Ram B. Singh, Ghizal Fatima, Sidrah Parvez, Ghazi Halabi, and Najah Hadi
Section E: Detection and biomarkers
42. Bronchoalveolar lavage (BAL) and use in detection of SARS-CoV-2
Nitesh Gupta, Sumita Agrawal, and Hari Kishan Gonuguntla
43. SARS-CoV-2 testing and vaccination among people who use drugs
Samantha Yeager, Abbie M. Sanders, Christopher G. Capron, and Camille C. Cioffi
44. Homocysteine as a biomarker in COVID-19
Adem Keskin
45. Assessment of smell and taste in COVID-19
Constantin A. Hintschich
46. S-gene analysis: RT-PCR and Sanger sequencing applied to SARS-CoV-2 virus
Takayuki Ishige
47. False-negative results in screening for SARS-CoV-2
Hidenori Takahashi
48. Sample pooling and SARS-CoV-2 assays
Miguel Hueda-Zavaleta, Fabrizzio Bardales-Silva, Diana Minchón-Vizconde, and Juan Carlos
Gomez de la Torre Pretel
49. Biomarkers of invasive mechanical ventilation in obesity and metabolic syndrome in patients
with COVID-19
Carles Perpiñan, Laia Bertran, and Teresa Auguet
Section F: Case studies with mini review
50. Hypoxia and heart-lung interactions in COVID-19: The significance of right heart dysfunction and shunt
Rajkumar Rajendram, Naveed Mahmood, Gabriele Via, and Arif Hussain
51. Ulnar nerve dysfunction as COVID-19 sequelae
Cristina Terhoeve, Ryan Bliss, and Rasheed Ahmad
52. Case study: Coronavirus disease 2019 and acute kidney injury
Yadullah Syed and Rajkumar Rajendram
53. Case study: The detection and treatment of a pneumothorax in a patient with coronavirus disease 2019 pneumonia
Rajkumar Rajendram and Arif Hussain
54. Proposal and demonstration of a survey method for the prevention of airborne transmission: Case studies in healthcare and welfare facilities
Yo Ishigaki, Naohisa Fujita, and Tatsuo Kato
Section G: Resources
55. Recommended resources for the features, transmission, and detection of coronavirus disease
2019 (COVID-19)
Rajkumar Rajendram, Daniel Gyamfi, Vinood B. Patel, and Victor R. Preedy
International and Life Course Aspects of COVID-19
Preface
Section A: Introductory chapters and setting the scene
1. COVID-19 and mortality in children
Milind Shinde, Anu Maheshwari, and Harish K. Pemde
2. Congenital and perinatal COVID-19: Diagnostic challenges, current management, and
outcomes
Angeliki Kontou, Eleftheria Hatzidaki, Kosmas Sarafidis, Gabriel Dimitriou, and Despoina Gkentzi
3. COVID-19 vaccine strategies
Amin Gasmi, Yuliya Semenova, Sadaf Noor, Amine Nehaoua, Rafiaa Malek, Habib Malek, and Geir Bjørklund
4. Social and community responses to public health and social measures for COVID-19: Community engagement for risk preparedness
Gary Ka-Ki Chung and Eng-Kiong Yeoh
Section B: International aspects
5. The COVID-19 pandemic in Italy: Ecological background and epidemiological dynamics
Marino Gatto and Stefano Miccoli
6 COVID-19 pandemic in Nigeria
Ademola Aiyenuro, Chijioke Obiwe Onyeani, Yusuff Adebayo Adebisi, Promise Udohchukwu Okereke, Deborah Oluwaseun Shomuyiwa, Nneka Catherine Uche, Nafisat Dasola Jimoh, Abdullahi Tunde Aborode, Udochiamaka Amarauche Chukwu, and Samuel Ogunsola
7. A bird’s eye view of the COVID-19 pandemic in India: The past, present, and future
Dhruv S. Gupta, Manoj Aswar, and Maushmi S. Kumar
8. COVID-19 pandemic in Europe Małgorzata Gruchoła and Małgorzata
Sławek-Czochra
9. COVID-19 in Latin America and the Caribbean (LAC)
Lorena Díaz de León-Martínez, Carlos Miguel López-Mendoza, Ana Jared Tenorio-Salazar, Rogelio Flores-Ramírez, and Luz Eugenia Alcántara-Quintana
10. COVID-19 in Sudan: A multiperspective review
Khabab Abbasher Hussien Mohamed Ahmed
11. Asymptomatic infection by SARSCoV-2 at the beginning of the epidemic in Cuba: Evidence from
case series
Elba Cruz Rodríguez, Niurka Molina Águila, Waldemar Baldoquin Rodríguez, Belkys María Galindo Santana, and María G. Guzmán
12. Stress and anxiety due to COVID-19 in India
Vidit Singh and Snigdha Awasthi
13. COVID-19 pandemic in Korea: A focus on medical management
Kyoo-Man Ha and Young T. Kim
14. Stigma experienced by healthcare workers during the COVID-19 pandemic: Global and Egyptian
perspectives
Aya Mostafa and Nashwa Ismail Basyoni
Section C: Reproduction, pregnancy and new-borns
15. The COVID-19 pandemic and breastfeeding
Bindi Borg and Karleen Gribble
16. Impact of SARS-CoV-2 infection on female fertility
Dalhia Abramovich, Yamila Herrero, Mayra Bordaquievich, Melanie Neira, and Fernanda Parborell
17. Fetal death due to maternal COVID-19
Munekage Yamaguchi
18. The COVID-19 pandemic and identification of SARS-CoV-2 in the prostate
Katherine Campbell, Nikhil Kulkarni, Braian Ledesma, Farah Rahman, Kyle Schuppe, Mohammed Zarli, Kajal Khodamoradi, and Ranjith Ramasamy
19. COVID-19 in pregnant women: Clinical course, treatment, and maternal/fetal outcome of vaccination during pregnancy
Cinzia Auriti, Chiara Maddaloni, and Domenico Umberto De Rose
20. Impact of the COVID-19 pandemic: SARS-CoV-2-specific IgG antibodies and their vertical
transfer
Jeremy D. Ward
21. COVID-19 vaccination during lactation
Amit Srivastava
22. Being pregnant during the COVID-19 pandemic: Impact of the trimester of gestation and measures of maternal mental health
Narimene Ait Belkacem, Jessica Gorgui, and Anick Bérard
23. COVID-19 related maternal mortality and SARS-CoV-2 variants
Arzu Bilge Tekin and Bilge Dogan Taymur
24. COVID-19-associated complications in pregnant women and neonates
Taylor DeAnnuntis, Jahnea Williams, Paul Burcher, Tamara Snyder, Rahul Kashyap, and Vikas Bansal
25. SARS-CoV-2 and its impact on the developing fetal neurologic system
Kartik Mody, Christine Wade, and Becky Micetic
26. Impact of maternal SARS-CoV-2 infection in the placenta
Kendall Moore, Rebecca H. Jessel, Jia Chen, and Corina Lesseur
Section D: Children and adolescents
27. T cells and their subsets in children with COVID-19
Abdurrahman Simsek, Muhammed Ali Kızmaz, and Ferah Budak
28. Pediatric inflammatory multisystem syndrome and SARS-CoV-2
Stanisław Surma, Joanna Lewek, and Maciej Banach
29. Impact of COVID-19 pandemic on nutritional status of children
Sharika Nuzhat and Mohammod Jobayer Chisti
30. COVID-19 in children: Nutrition care
Patrícia Zamberlan, Beatriz Polisel Mazzoni, Ana Lúcia Capelari Lahoz, Maria Lúcia Barbosa Maia dos Santos, Camila Nozella, and Artur Figueiredo Delgado
31. Eating disorders in children during the COVID-19 pandemic
Marchili Maria Rosaria, Giulia Spina, Cristina Mascolo, and Alberto Villani
32. Body composition in children with SARS-CoV-2 infection: Short and long term consequences
Elisabetta Di Profio, Elvira Verduci, and Gianvincenzo Zuccotti
33. Risk of SARS-CoV-2 infection and childhood obesity
Maira Alejandra Ortiz-Pinto, Honorato Ortiz Marrón, and Miguel Pedromingo Kuss
34. The impact of the COVID-19 pandemic during the lockdown and the post-COVID-19 effects on
the family system of children with disabilities
Bekir Fatih Meral
35. The impact of the COVID-19 pandemic on ordinary vaccination programs for very young children: BCG, MMR, poliomyelitis, and beyond
Guilherme Silveira Procianoy and Rita C Silveira
36. Immune responses to SARS-CoV-2 infection and vaccination in children
Zheng Quan Toh, Nadia Mazarakis, and Paul V. Licciardi
37. The impact of the COVID-19 pandemic: How physical fitness changes in children
Eliseo Iglesias-Soler, Jessica Rial-Vázquez, María Rúa-Alonso, Iván Nine, and Iván Clavel
38. The COVID-19 pandemic and children: Impact on physical activity
Olena Yelizarova, Svitlana Hozak, Tetiana Stankevych, Nadiya Polka, Alla Koblianska, Alla Parats, and Olha Ivanovska
39. The COVID-19 pandemic and stress related to schooling
Xue Yang and Kylie K.Y. Chan
40. Suicidal thoughts and behaviors among adolescents during the COVID-19 pandemic
Christina L. Robillard, Alice Shen, and Brianna J. Turner
41. The COVID-19 pandemic: Attending to hand hygiene measures in young people
(a review of different studies)
Anna Espart, Luisa Guitard-Sein Echaluce, Maria Barcenilla-Guitard, Alba Guitard-Quer, and Fernando Barcenilla
42. Child and adolescent COVID-19 vaccination: Trends, hesitancy, and strategies for increasing vaccination
Kimberly H. Nguyen, Lavanya Vasudevan, and Robert A. Bednarczyk
43. Social distancing behavior and mental health in US adolescents during the COVID-19 pandemic
Ming-Te Wang, Christina L. Scanlon, Ashley Sunjae Lee, and Ariana C. Henderson
44. Thrombotic complications in children and adolescents with SARS-CoV-2 infection
Clay T. Cohen, Dalia A. Bashir, and Sarah E. Sartain
45. Features of SARS-CoV-2 infection and vaccination in children: A focus on magnetic resonance imaging of the heart
Łukasz A. Małek
46. SARS-CoV-2 infection and the cytokine levels and pathway in children: An updated narrative
Tsvetelina Velikova and Snezhina Lazova
Section E: Older adults
47. Risk factors related to COVID-19 among older adults
Eva M. Satué-Gracia, Albert del Pozo-Niubo, María-José Forcadell-Peris, Cinta de Diego-Cabanes, Angel Vila-Córcoles, and Francisco M. Martín-Luján
48. Reducing loneliness and social isolation among the elderly during the COVID-19 pandemic
Xiangfei Meng, Muzi Li, and Yingying Su
49. Features and measures of depression in the elderly and the impact of the COVID-19
pandemic: Linking in preexisting mental health
Omar Paccagnella
50. Experiences of disabled older adults in adult day care centers during the COVID-19 pandemic
Takashi Naruse
51. Using single-cell analysis to investigate disease severity in elderly patients with COVID-19
Sherine K. Saber, Ahmed S. Abouhashem, Ahmed A. Elbaz, Sedat Kacar, Kanhaiya Singh, Chandan K. Sen, and Hassan M.E. Azzazy
52. COVID-19 and older adult food practices: A social determinants of health perspective
Sarah L. Francis, Catherine S. Rudolph, and Savannah Schultz
53. Older subjects and immunogenicity of mRNA COVID-19 vaccines
Piotr Seiffert and Dorota Religa
54. Noninvasive respiratory support in octogenarian patients with COVID-19
Federico Lionello, Gabriella Guarnieri, Giovanna Arcaro, Sara Lococo, and Andrea Vianello
Section F: Case studies with mini review
55. Case study: COVID-19 severity in diabetic patients with and without seizure
Budhadev Baral, Kartik Muduli, Shweta Jakhmola, Vaishali Saini, Pratik Kundu, Nikunj Kumar Rout, Shubhransu Patro, Nirmal Kumar Mohakud, and Hem Chandra Jha
56. Case study: Nonpharmaceutical interventions for COVID-19 and their social impact in Japan
Makoto Niwa, Shintaro Sengoku, and Kota Kodama
57. Case study: Factors affecting vaccine uptake—Australian perspectives
Jessica Carter and Erika Borkoles
58. The impact of the COVID-19 pandemic on an older disabled person
Takashi Naruse
59. COVID-19 in the newborn: Clinical course and effects of maternal vaccination in pregnancy
Cinzia Auriti, Chiara Maddaloni, and Domenico Umberto De Rose
Section G: Resources
60. Recommended resources for the international and life course aspects of coronavirus disease 2019 (COVID-19)
Rajkumar Rajendram, Daniel Gyamfi, Vinood B. Patel, and Victor R. Preedy
Linking Neuroscience and Behavior in COVID-19
Preface
Section A: Introductory chapters and setting the scene
1. The historical aspects of the SARS-CoV-2 virus and the ensuing pandemic
Taslima Nasrin, Md Samim Hassan, Arijit Samanta, Mehboob Hoque, and Safdar Ali
2. Different variants of SARS-CoV-2
Arijit Samanta, Md Samim Hassan, Taslima Nasrin, Syed Sahajada Mahafujul Alam, Zarnain Jamil, Harpal S. Buttar, Safdar Ali, and Mehboob Hoque
3. Lateral flow assay for SARS-CoV-2 infection: Uses and limitations
Mirajul Islam, Taslima Nasrin, Arijit Samanta, Safdar Ali, Harpal S. Buttar, and Mehboob Hoque
4. Linking community participation, mobility disabilities, and the COVID-19 pandemic
Kara B. Ayers, Jean P. Hall, and Claire Burdick
5. Influence of the sources used to obtain information on COVID-19 and their impact on mental health
Juan Gómez-Salgado, Juan Jesús García-Iglesias, Regina Allande-Cussó, and Carlos Ruiz-Frutos
Section B: Impact on behavior and psychology
6. The psychological experiences and distress of defined populations in the COVID-19 pandemic: Doctors
Amy Pascoe, Karen Willis, and Natasha Smallwood
7. Impact of COVID-19 on behavior in autism spectrum disorder
Giulia Antolini and Marco Colizzi
8. Prepandemic stressors in mental health responses to the COVID-19 pandemic: Early life adversities and beyond
Xiangfei Meng
9. Compulsive hoarding in the COVID-19 pandemic
Nicole Loren Angelo, Andrea Pozza, Debora Rossi, Ilaria Aicardi, Giulia Chieppa, Isabella Bove, Federica Ragucci, Francesco Iocca, Daniele Pugi, and Donatella Marazziti
10. The psychological experiences and distress in Japan and Sweden during the COVID-19 pandemic
Sayo Hamatani, Anton K€all, Konomi Shoda, and Kazuki Matsumoto
11. The COVID-19 pandemic, mental health, and sleep: Linking depression, anxiety, and perceived
stress
Joana Bücker, Adriane Ribeiro Rosa, and Letícia Sanguinetti Czepielewski
12. The Covid-19 pandemic and the occupational overload of health professionals: Indicators of
burnout
Isabella Lara Machado Silveira, Flávia de Lima Osório, and Sonia Regina Loureiro
13. Neurocognitive sequelae of SARS-CoV-2 infection: Pathogenesis, risk factors, assessment, and implications
Mohammad Nazmus Sakib
14. Acute neurocognitive disorder as a presenting manifestation of COVID-19
Brad Tyson, Leigh Tyson, Sudeshna Ray, and Pinky Agarwal
15. Mental health and the impact of confinement
Lorabi Souhib, David Sánchez-Teruel, Selma Boufellous, and María Auxiliadora Robles-Bello
16. Cannabis use in the COVID-19 pandemic: Changes in different populations and implications
for policy
Adam Zaweel, Isaac Kuk, Soyeon Kim, Bernard Le Foll, and Christine M. Wickens
17. Impact of COVID-19 on mental health in women: Socioeconomic groups and global aspects
Khushi Kumar, Aashni Udani, and Maushmi S. Kumar
18. Quality of life assessment of patients after COVID-19
Eleni Tsimitrea, Paraskevi Siamouti, Konstntinos I. Gourgoulianis, and Evangelos C. Fradelos
19. COVID-19 pandemic and remote working: Toward a new way of working
Ferdinando Toscano and Teresa Galanti
20. Long COVID and its persistence: A focus on mental health
Michael John Dwyer, Massimo Mirandola, and Elda Righi
21. The impact of the COVID-19 pandemic on behavioral and psychological features of vulnerable groups: Patients with multiple sclerosis and their quality of life
Kubra Yeni
Section C: Effects on neurological structures and mechanisms
23. Linking pediatric COVID-19 with basal ganglia and dentate nucleus
Shraddha Sunthwal, Sagar Lad, and Preeti Lad
24. Sensory disorders, neuroinflammation, and COVID-19
Pietro De Luca and Arianna Di Stadio
25. The effects of COVID-19 isolations on nonmotor features of Parkinson’s disease
Santangelo Gabriella and Carmine Vitale
26. Myelitis following COVID-19: The road so far
Cristiana Silva and Sónia Batista
27. The corpus callosum: Effects due to SARS-CoV-2 infection and the mRNA vaccine
Luca Procaccini and Antonio Bernardini
28. Assessing the impact of prenatal SARS-CoV-2 exposure on infants’ neurodevelopment: A comprehensive analysis of current evidence
Fernanda Nava and Vania Aldrete-Cortez
29. Electroencephalographic features with COVID-19
Isabel M. Sáez-Landete, Adriana Gómez-Domínguez, Beatriz Estrella-León, and Alba Díaz-Cid
30. Survivors of COVID-19 and clinical neuropsychological domain characteristics
Pamela E. May-Weeks and Vaishali Phatak
31. Neuroinflammation following SARS-CoV-2 infection
Carlos Alexandre Netto and Marimelia A Porcionatto
32. Functional magnetic resonance imaging and depressive symptoms in subjects with COVID-19
Giulia Cattarinussi, Alessandro Miola, and Fabio Sambataro
33. Impact of COVID-19 on the brain: Antibodies against brain stem antigens
Guglielmo Lucchese, Antje Vogelgesang, Angela Stufano, and Agnes Flöel
34. The kynurenine pathway and role in mental health of post-COVID-19 patients
Melike Kucukkarapinar, Filiz Karadag, and Selcuk Candansayar
Section D: Management, support and treatments
35. Management of brain tumors in the COVID-19 pandemic
Rajesh Balakrishnan, Sharief K. Sidhique, Patricia Sebastian, and Selvamani Backianathan
36. The impact of the COVID-19 pandemic on ischemic stroke management: From hyperacute to chronic phase
Irene Scala, Simone Bellavia, Aldobrando Broccolini, Giovanni Frisullo, Pier Andrea Rizzo, Eleonora Rollo, Giacomo Della Marca, and Valerio Brunetti
37. Long COVID and the potential use of palmitoylethanolamide
Rocco Salvatore Calabro` and Loredana Raciti
38. Cognitive assessments in post-COVID syndrome: A focus on the neuropsychological tests and
protocols
Cristina Delgado-Alonso and Jordi A. Matias-Guiu
39. Supporting individuals with intellectual and developmental disabilities during the COVID-19
pandemic
David Ervin, Melody Jan, Emily J. Johnson, Lin Peters, and Carl Tyler
40. Preserving well-being and quality of life through school-based interventions focused on physical
activity during the COVID-19 pandemic
Alice Masini, Francesco Sanmarchi, and Laura Dallolio
41. Hesitancy in using COVID 19 prevention behaviors among African Americans: Strategies to
build confidence
Jennifer Cunningham Erves, Jamaine Davis, Elizabeth C. Stewart, Vanessa B. Crowther, and Whitney George
42. New strategies for psychological well-being at work
Teresa Galanti and Ferdinando Toscano
43. Mitigating mental health changes with virtual reality technology during Covid-19: A narrative
Muhammad Hizri Hatta, Chong Siew Koon, and Suriati Mohamed Saini
44. Music therapy for patients with neurological disorders during COVID-19 pandemic
Claudia Vinciguerra, Salvatore Iacono, Vincenzo Di Stefano, Valerio Nardone, and Antonio Federico
45. Mental health and the modulating effects of receiving the COVID-19 vaccination
Natsu Sasaki and Norito Kawakami
46. Personalized cognitive behavioral therapy on patients with obesity in COVID-19 pandemic
Riccardo Dalle Grave, Anna Dalle Grave, and Simona Calugi
47. Social anxiety disorder and Covid 19: Treatment with cognitive behavioral therapy
Narendra Nath Samantaray and Sapam Kiran Dolly
48. Burnout during the COVID-19 pandemic: Modulating role of mindfulness
Makiko Sampei and Naho Morisaki
Section E: Case studies with mini review
49. Case study: Evaluation of a long Covid assessment service (LCAS)
Colin R. Martin, Scarlett Maloney, Sarah Fowler, Frances Farnworth, Katie Tyrrell, and Abigail Webb
50. Case study: Navigating youth mental health and addictions care in the context of the COVID-19 pandemic
Roula Markoulakis and Anthony Levitt
51. Case study: Restless leg syndrome associated with COVID-19
Cyprian Popescu
Section F: Resources
52. Recommended resources for linking neuroscience and behavior in coronavirus disease
(COVID-19)
Rajkumar Rajendram, Daniel Gyamfi, Vinood B. Patel, and Victor R. Preedy
Management, Body Systems, and Case Studies in COVID-19
Preface
Section A: Introductory chapters and setting the scene
1. Hand hygiene strategies
Trinidad Montero-Vilchez, Clara-Amanda Ureña-Paniego, Alberto Soto-Moreno, Alejandro Molina-Leyva, and Salvador Arias-Santiago
2. Approved vaccines for the COVID-19 pandemic: Linking in future perspectives
Larissa Moraes dos Santos Fonseca, Katharine Valéria Saraiva Hodel, Vinícius Pinto Costa Rocha, Milena Botelho Pereira Soares, and Bruna Aparecida Souza Machado
3. Molecular methods for SARS-CoV-2 variant detection
Marco Fabiani, Katia Margiotti, Francesca Monaco, Alvaro Mesoraca, and Claudio Giorlandino
Section B: Management
4. Systematic patient assessment for acute respiratory tract ailments (SPARTA): A simple tool to improve outcomes from COVID-19
Rajkumar Rajendram, Naveed Mahmood, Mohammad Ayaz Khan, and Hamdan Al-Jahdali
5. Point of care ultrasound for coronavirus disease 2019: The multiorgan approach to COVID-19
Rajkumar Rajendram
6. COVID-19 in patients with inflammatory bowel diseases: Features and guidelines
Carlos Taxonera and Olga Neva López-García
7. Management of COVID-19 and clinical nutrition
Manola Peverini and Giacomo Barberini
8. The management of head and neck cancer in COVID-19
Jesús Herranz-Larrañeta, Pablo Parente-Arias, Carlos Chiesa-Estomba, and
Miguel Mayo-Yáñez
9. The COVID-19 pandemic: Inventory management and allocation of personal protective
equipment
Tazim Merchant and Mark Sheldon
10. Clinical management in the COVID-19 pandemic: Rheumatic disease
Abdulvahap Kahveci and Şebnem Ataman
11. Managing migraines during the COVID-19 pandemic: An Italian experience
Licia Grazzi, Danilo Antonio Montisano, and Paul Rizzoli
12. Managing acute ischemic stroke in the SARS-CoV-2 pandemic
Adele S. Budiansky, Wesley Rajaleelan, and Tumul Chowdhury
13. Impact of the coronavirus disease 2019 pandemic on patients with hypertension
Kazuo Kobayashi and Kouichi Tamura
14. Neurosurgical trauma management during COVID-19 restrictions
James Zhou, Michael Zhang, and Harminder Singh
15. The COVID-19 pandemic and management of weight gain: Implications for obesity
Sarah R. Barenbaum and Alpana P. Shukla
16. COVID-19 and the management of heart failure using telemedicine
Maria Margarida Andrade, Diogo Cruz, and Marta Afonso Nogueira
Section C: Guidelines for different treatment clinics
17. Guidelines for breast imaging in the COVID-19 pandemic
Daniele Ugo Tari
18. Vaccine-induced (immune) thrombotic thrombocytopenia (VITT): Diagnosis, guidelines,
and reporting
Emmanuel J. Favaloro, Leonardo Pasalic, and Giuseppe Lippi
19. Lung cancer in the era of COVID-19
Shehab Mohamed, Monica Casiraghi, Lorenzo Spaggiari, and Luca Bertolaccini
20. Multisystem inflammatory syndrome in children/pediatric inflammatory multisystem
syndrome: Clinical guidelines
Arthur J. Chang, Ramesh Kordi, and Mark D. Hicar
Section D: Impact on the respiratory system
21. Ground-glass nodules in the lungs of COVID-19 patients
Noel Roig-Marín
22. Cardiothoracic imaging in patients affected by COVID-19
Tommaso D’Angelo, Ludovica R.M. Lanzafame, M. Ludovica Carerj, Antonino Micari, Silvio Mazziotti, and Christian Booz
23. Cystic fibrosis and bronchial epithelial cells in SARS-CoV-2 infection
Anna Lagni, Erica Diani, Davide Gibellini, and Virginia Lotti
24. Biomechanics and mechanobiology of the lung parenchyma following SARS-CoV-2 infection
Béla Suki, András Lorx, and Erzsébet Bartolák-Suki
25. Long noncoding RNA profiling in respiratory specimens from COVID-19 patients
Marta Molinero, Carlos Rodríguez-Muñoz, Silvia Gómez, Ángel Estella, Ferran Barbé, and David de Gonzalo-Calvo
26. COVID-19 and acute pulmonary embolism
Marco Zuin and Gianluca Rigatelli
27. The usefulness of the alveolar-arteriolar gradient during the COVID-19 pandemic
Giuseppe Pipitone, Miriam De Michele, Massimo Sartelli, Francesco Onorato, Claudia Imburgia, Antonio Cascio, and Chiara Iaria
Section E: Effects on cardiovascular and hematological systems
28. Cardiac manifestations of COVID-19: An overview
Naveed Rahman, Mirza H. Ali, Aanchal Sawhney, Apurva Vyas, and Rahul Gupta
29. Limb ischemia and COVID-19
Raffaello Bellosta, Sara Allievi, Luca Attisani, Luca Luzzani, and Matteo Alberto Pegorer
30. Thrombosis and coagulopathy in COVID-19: A new narrative
Alejandro Lazo-Langner and Mateo Porres-Aguilar
31. COVID-19 myocarditis: Features of echocardiography
Antonello D’Andrea, Dario Fabiani, Francesco Sabatella, Carmen Del Giudice, Luigi Cante, Adriano Caputo, Stefano Palermi, Francesco Giallauria, and Vincenzo Russo
32. COVID-19 lockdown and impact on arrhythmias
Valentino Ducceschi and Giovanni Domenico Ciriello
33. Cardiometabolic disease and COVID-19: A new narrative
Mohamad B. Taha, Bharat Narasimhan, Eleonora Avenatti, Aayush Shah, and Wilbert S. Aronow
34. Postrecovery COVID-19 and interlinking diabetes and cardiovascular events
Giuseppe Seghieri
35. COVID-19 patients and extracorporeal membrane oxygenation
Mario Castano, Pasquale Maiorano, Laura Castillo, Gregorio Laguna, Guillermo Muniz-Albaiceta, Victor Sagredo, Elio Marin-Gutierrez, and Javier Gualis
36. Sars-CoV-2 infection in different hematological patients
Saša Anžej Doma
Section F: Effects on body systems
37. Dermatological reactions associated with personal protective equipment use during
the COVID-19 pandemic
Nicholas Herzer, Fletcher G. Young, Chrystie Nguyen, Aniruddha Singh, and Doug McElroy
38. Hemodialysis patients, effects of infections by SARS-CoV-2 and vaccine response
Diana Rodríguez-Espinosa, Elena Cuadrado-Payán, and José Jesús Broseta
39. Coinfections with COVID-19: A focus on tuberculosis (TB)
Chijioke Obiwe Onyeani, Dimo Chisom Precious, Emmanuel Ebuka Elebesunu, Malachy Ekene Ezema, Samuel Ogunsola, and Ademola Aiyenuro
40. Patients with autoimmune liver disease and the impact of Sars-COV-2 infection
Annarosa Floreani, Sara De Martin, and Nora Cazzagon
41. COVID-19 severity and nonalcoholic fatty liver disease
Nina Vrsaljko, Branimir Gjurašin, and Neven Papić
42. Changes in obesity and diabetes severity during the COVID-19 pandemic at Virginia
Commonwealth University health system
Asmaa M. Namoos, Vanessa Sheppard, NourEldin Abosamak, Martin Lavallee, Rana Ramadan, Estelle Eyob, Chen Wang, and Tamas S. Gal
43. The diabetic patient and concomitant conditions rhinoorbital-cerebral mucormycosis
and COVID-19
Caglar Eker
44. Tissue location of SARS-CoV-2 RNA: A focus on bone and implications for skeletal health
Edoardo Guazzoni, Luigi di Filippo, Alberto Castelli, Andrea Giustina, and Federico Grassi
45. Linking between gastrointestinal tract effects of COVID-19 and tryptophan metabolism
Yoshihiro Yokoyama and Hiroshi Nakase
46. Organ damage in SARS-CoV-2 infection in children: A focus on acute kidney injury
Girish Chandra Bhatt, Yogendra Singh Yadav, and Tanya Sharma
47. Obesity, COVID-19 severity, and mortality
Riecha Joshi, Aarushi Sudan, Akshat Banga, Rahul Kashyap, and Vikas Bansal
48. Upper and lower gastrointestinal symptoms and manifestations of COVID-19
Brittany Woods, Priyal Mehta, Gowthami Sai Kogilathota Jagirdhar, Rahul Kashyap, and Vikas Bansal
49. The COVID-19 survivors: Impact on skeletal muscle strength
Renata Gonçalves Mendes, Alessandro Domingues Heubel, Naiara Tais Leonardi, Stephanie Nogueira Linares, Vanessa Teixeira do Amaral, and Emmanuel Gomes Ciolac
Section G: Case studies with mini review
50. A case report: COVID-19 meningoencephalitis and intracranial hemorrhage
Mohammad Alolama, Anas Rashid, and Debora Garozzo
51. Case study: Oral mucosal lesions in patients with COVID-19
Juliana Amorim dos Santos, Rainier Luiz Carvalho da Silva, and Eliete Neves Silva Guerra
52. Case study: COVID-19 pneumonia presented with cavitary lesions
Bahadır M. Berktaş
53. Case study: Optic neuritis in SARS-CoV-2 infection
Md Moshiur Rahman
Section H: Resources
54. Recommended resources relevant to the body systems involvement
and management of COVID-19
Rajkumar Rajendram, Daniel Gyamfi, Vinood B. Patel, and Victor R. Preedy
Preface
Section A: SARS-CoV-2 and COVID-19: Introductory chapters and setting the scene
1. Coronavirus disease 2019 (COVID-19) pandemic in context: Systemic effects
Rajkumar Rajendram, Vinood B. Patel, and Victor R. Preedy
2. Early warning of SARS-CoV-2 infection
Daniele Proverbio, Françoise Kemp, and Jorge Gonçalves
3. Mobile phones and their use to study dynamics of the COVID-19 pandemic
Alex Berke and Kent Larson
Section B: Structure, transmission and avoidance
4. Cis regulatory elements: A novel communication route between the host cell and the SARS-CoV-2 genome
Barsanjit Mazumder and Anton A. Komar
5. SARS-CoV-2 ORF8: Structure, evolution, molecular function, and its contribution to the
pathogenicity of the virus
Muhamad Fahmi, Yukihiko Kubota, and Masahiro Ito
6. SARS-CoV-2 spike protein binding ligands and its application in COVID-19 therapeutics
Westley Van Zant, Gustavo Felippe Da Silva, Maria De Lourdes Borba Magalhães, and
Partha Ray
7. SARS-CoV-2 bulldozes the autophagy pathway and unhinges mitochondrial quality control
thereby driving neurodegeneration—A hypothesis
Ben Loos and Tamryn Barron
8. The Omicron variant of SARS-CoV-2
José Luis Zambrano, Rossana C. Jaspe, Carmen L. Loureiro, Héctor R. Rangel, Ferdinando Liprandi, and Flor H. Pujol
9. Monitoring SARS-CoV-2 spread in hospitals
Vincenzo Romano Spica and Antonio Piccolella
10. Computational analysis of mutations in SARS-CoV-2 variants spike protein and protein
interactions
Eduardo U.M. Moreira, Diego C.B. Mariano, and Raquel C. de Melo-Minardi
11. Airborne transmission of SARS-CoV-2
Andrew Fox-Lewis
12. Reducing transmission of SARS-CoV-2 with face masks: Its potential protective effects
Cristiane M. Eller, Vinicius M. Mello, and Marco A.P. Horta
13. Digital twin of ventilation system against COVID-19 transmission and infection risk
Jonathan Koon Ngee Tan and Adrian Wing-Keung Law
14. Pets and SARS-CoV-2: What is their role in the epidemiology of the disease?
Sandra Barroso-Arévalo and José M. Sánchez-Vizcaíno
15. SARS-CoV-2 transmission in dental practice
Hironori Sakai, Eiji Kondo, Hirokazu Tanaka, Tetsu Shimane, Masao Hashidume, and
Hiroshi Kurita
16. SARS-CoV-2 compared with influenza and respiratory syncytial virus in terms of vertical
transmission
Sara Manti and Giovanni Piedimonte
17. Reducing droplets and aerosols in the surgical setting and applications to the COVID-19
pandemic
Belén Salvatierra-Vicario and Jaime Viera-Artiles
18. SARS-CoV motion dynamics: Linking in droplet size
Mehmet Aydin and Seckin Aydin Savas
19. Ventilation and airborne particles in classrooms: Implications for the COVID-19 pandemic
Marta F. Gabriel, Fátima Felgueiras, and Gonçalo Marques
20. Indoor transmission of the SARS-CoV-2 virus through aerosols emitted by e-cigarettes
Roberto A. Sussman
Section C: Impact and effects
21. The Impact of COVID-19 on first responders
Brian T. Montague, Larissa Pisney, and Eric A.F. Simões
22. COVID-19 and suspected drug-induced liver injury
Rolf Teschke and Axel Eickhoff
23. Pulmonary fibrosis in COVID-19
Ryosuke Imai and Naoki Nishimura
24. The effect of SARS-CoV-2 infection on cancer: Clinical correlation and
potential pathological mechanism
Trien Trey Tang, Syed Ahad Muhammad Haidry, Cade Lewis, and Yujiang Fang
25. Severe SARS-CoV-2, plateletendothelium interactions, and cardiovascular injury
Theresa M. Rossouw, Ronald Anderson, and Charles Feldman
26. Cardiometabolic syndrome and COVID-19: Pathophysiological aspects
Subo Dey, Wojciech Rzechorzek, and Wilbert Aronow
27. COVID-19 and type 1 and 2 diabetes: An overview
Vahid Reza Askari and Vafa Baradaran Rahimi
28. COVID-19 and older adults: An overview
Vahid Reza Askari and Vafa Baradaran Rahimi
29. COVID-19 and male fertility
Mohammad Reza Fadaei, Mohammad Mahdi Dabaghi, Mohammad Saleh Fadaei, Vafa Baradaran Rahimi, and Vahid Reza Askari
30. COVID-19 and obesity: An overview
Vahid Reza Askari, Matin Shirazinia, Mohammad Saleh Fadaei, and Vafa Baradaran Rahimi
Section D: Treatments, strategies, and vaccines
31. COVD-19 vaccines and their impact: An overview
Ka Wa Khong and Ivan F.N. Hung
32. Exploring the promise of COVID-19 vaccines: A review of preclinical studies
Shubham Adhikary, Harpal S. Buttar, Hardeep Singh Tuli, and Ginpreet Kaur
33. Drugs actively being investigated for use in COVID-19
Ruiqi Zhang and Ivan F.N. Hung
34. The biology of neutralizing antibody therapy with REGEN-COV
Hiroaki Sasaki
35. The intensive care unit and percutaneous tracheostomy in patients with coronavirus disease
2019
Burhan Dost and Ozgür Kömürcü
36. Cardiac effects of drugs and vaccines used to treat and prevent COVID-19
Luigi X. Cubeddu and Marylee Tailor
37. COVID-19 pandemic and isolation: Impact on sleep
Maria Beatriz Duarte Gavião, Camila Rita Vicente Marceliano, and Dora Zulema Romero Diaz
38. Strategies in the COVID-19 pandemic: Disinfection of gloved hands
Verónica V. Márquez-Hernández, Lorena Gutiérrez-Puertas, Alba García-Viola, José Miguel Garrido-Molina, Alfredo Alcayde-García, and Gabriel Aguilera-Manrique
39. In silico studies on established antivirals on SARS-CoV-2 RNAdependent RNA polymerase
Ismail Celik, Meryem Erol, and Trina Ekawati Tallei
40. The COVID-19 cytokine storm and its immunomodulatory treatment
Maha Mohamed Saber-Ayad, Iman Mamdouh Talaat, Rakhee Kizhuvappat Ramakrishnan, and Nada
Mahmoud Soliman Yakout
41. Safety and efficacy of nebulization for reducing the intensity of viral load and clinical manifestations in patients with COVID-19
Ram B. Singh, Ghizal Fatima, Sidrah Parvez, Ghazi Halabi, and Najah Hadi
Section E: Detection and biomarkers
42. Bronchoalveolar lavage (BAL) and use in detection of SARS-CoV-2
Nitesh Gupta, Sumita Agrawal, and Hari Kishan Gonuguntla
43. SARS-CoV-2 testing and vaccination among people who use drugs
Samantha Yeager, Abbie M. Sanders, Christopher G. Capron, and Camille C. Cioffi
44. Homocysteine as a biomarker in COVID-19
Adem Keskin
45. Assessment of smell and taste in COVID-19
Constantin A. Hintschich
46. S-gene analysis: RT-PCR and Sanger sequencing applied to SARS-CoV-2 virus
Takayuki Ishige
47. False-negative results in screening for SARS-CoV-2
Hidenori Takahashi
48. Sample pooling and SARS-CoV-2 assays
Miguel Hueda-Zavaleta, Fabrizzio Bardales-Silva, Diana Minchón-Vizconde, and Juan Carlos
Gomez de la Torre Pretel
49. Biomarkers of invasive mechanical ventilation in obesity and metabolic syndrome in patients
with COVID-19
Carles Perpiñan, Laia Bertran, and Teresa Auguet
Section F: Case studies with mini review
50. Hypoxia and heart-lung interactions in COVID-19: The significance of right heart dysfunction and shunt
Rajkumar Rajendram, Naveed Mahmood, Gabriele Via, and Arif Hussain
51. Ulnar nerve dysfunction as COVID-19 sequelae
Cristina Terhoeve, Ryan Bliss, and Rasheed Ahmad
52. Case study: Coronavirus disease 2019 and acute kidney injury
Yadullah Syed and Rajkumar Rajendram
53. Case study: The detection and treatment of a pneumothorax in a patient with coronavirus disease 2019 pneumonia
Rajkumar Rajendram and Arif Hussain
54. Proposal and demonstration of a survey method for the prevention of airborne transmission: Case studies in healthcare and welfare facilities
Yo Ishigaki, Naohisa Fujita, and Tatsuo Kato
Section G: Resources
55. Recommended resources for the features, transmission, and detection of coronavirus disease
2019 (COVID-19)
Rajkumar Rajendram, Daniel Gyamfi, Vinood B. Patel, and Victor R. Preedy
International and Life Course Aspects of COVID-19
Preface
Section A: Introductory chapters and setting the scene
1. COVID-19 and mortality in children
Milind Shinde, Anu Maheshwari, and Harish K. Pemde
2. Congenital and perinatal COVID-19: Diagnostic challenges, current management, and
outcomes
Angeliki Kontou, Eleftheria Hatzidaki, Kosmas Sarafidis, Gabriel Dimitriou, and Despoina Gkentzi
3. COVID-19 vaccine strategies
Amin Gasmi, Yuliya Semenova, Sadaf Noor, Amine Nehaoua, Rafiaa Malek, Habib Malek, and Geir Bjørklund
4. Social and community responses to public health and social measures for COVID-19: Community engagement for risk preparedness
Gary Ka-Ki Chung and Eng-Kiong Yeoh
Section B: International aspects
5. The COVID-19 pandemic in Italy: Ecological background and epidemiological dynamics
Marino Gatto and Stefano Miccoli
6 COVID-19 pandemic in Nigeria
Ademola Aiyenuro, Chijioke Obiwe Onyeani, Yusuff Adebayo Adebisi, Promise Udohchukwu Okereke, Deborah Oluwaseun Shomuyiwa, Nneka Catherine Uche, Nafisat Dasola Jimoh, Abdullahi Tunde Aborode, Udochiamaka Amarauche Chukwu, and Samuel Ogunsola
7. A bird’s eye view of the COVID-19 pandemic in India: The past, present, and future
Dhruv S. Gupta, Manoj Aswar, and Maushmi S. Kumar
8. COVID-19 pandemic in Europe Małgorzata Gruchoła and Małgorzata
Sławek-Czochra
9. COVID-19 in Latin America and the Caribbean (LAC)
Lorena Díaz de León-Martínez, Carlos Miguel López-Mendoza, Ana Jared Tenorio-Salazar, Rogelio Flores-Ramírez, and Luz Eugenia Alcántara-Quintana
10. COVID-19 in Sudan: A multiperspective review
Khabab Abbasher Hussien Mohamed Ahmed
11. Asymptomatic infection by SARSCoV-2 at the beginning of the epidemic in Cuba: Evidence from
case series
Elba Cruz Rodríguez, Niurka Molina Águila, Waldemar Baldoquin Rodríguez, Belkys María Galindo Santana, and María G. Guzmán
12. Stress and anxiety due to COVID-19 in India
Vidit Singh and Snigdha Awasthi
13. COVID-19 pandemic in Korea: A focus on medical management
Kyoo-Man Ha and Young T. Kim
14. Stigma experienced by healthcare workers during the COVID-19 pandemic: Global and Egyptian
perspectives
Aya Mostafa and Nashwa Ismail Basyoni
Section C: Reproduction, pregnancy and new-borns
15. The COVID-19 pandemic and breastfeeding
Bindi Borg and Karleen Gribble
16. Impact of SARS-CoV-2 infection on female fertility
Dalhia Abramovich, Yamila Herrero, Mayra Bordaquievich, Melanie Neira, and Fernanda Parborell
17. Fetal death due to maternal COVID-19
Munekage Yamaguchi
18. The COVID-19 pandemic and identification of SARS-CoV-2 in the prostate
Katherine Campbell, Nikhil Kulkarni, Braian Ledesma, Farah Rahman, Kyle Schuppe, Mohammed Zarli, Kajal Khodamoradi, and Ranjith Ramasamy
19. COVID-19 in pregnant women: Clinical course, treatment, and maternal/fetal outcome of vaccination during pregnancy
Cinzia Auriti, Chiara Maddaloni, and Domenico Umberto De Rose
20. Impact of the COVID-19 pandemic: SARS-CoV-2-specific IgG antibodies and their vertical
transfer
Jeremy D. Ward
21. COVID-19 vaccination during lactation
Amit Srivastava
22. Being pregnant during the COVID-19 pandemic: Impact of the trimester of gestation and measures of maternal mental health
Narimene Ait Belkacem, Jessica Gorgui, and Anick Bérard
23. COVID-19 related maternal mortality and SARS-CoV-2 variants
Arzu Bilge Tekin and Bilge Dogan Taymur
24. COVID-19-associated complications in pregnant women and neonates
Taylor DeAnnuntis, Jahnea Williams, Paul Burcher, Tamara Snyder, Rahul Kashyap, and Vikas Bansal
25. SARS-CoV-2 and its impact on the developing fetal neurologic system
Kartik Mody, Christine Wade, and Becky Micetic
26. Impact of maternal SARS-CoV-2 infection in the placenta
Kendall Moore, Rebecca H. Jessel, Jia Chen, and Corina Lesseur
Section D: Children and adolescents
27. T cells and their subsets in children with COVID-19
Abdurrahman Simsek, Muhammed Ali Kızmaz, and Ferah Budak
28. Pediatric inflammatory multisystem syndrome and SARS-CoV-2
Stanisław Surma, Joanna Lewek, and Maciej Banach
29. Impact of COVID-19 pandemic on nutritional status of children
Sharika Nuzhat and Mohammod Jobayer Chisti
30. COVID-19 in children: Nutrition care
Patrícia Zamberlan, Beatriz Polisel Mazzoni, Ana Lúcia Capelari Lahoz, Maria Lúcia Barbosa Maia dos Santos, Camila Nozella, and Artur Figueiredo Delgado
31. Eating disorders in children during the COVID-19 pandemic
Marchili Maria Rosaria, Giulia Spina, Cristina Mascolo, and Alberto Villani
32. Body composition in children with SARS-CoV-2 infection: Short and long term consequences
Elisabetta Di Profio, Elvira Verduci, and Gianvincenzo Zuccotti
33. Risk of SARS-CoV-2 infection and childhood obesity
Maira Alejandra Ortiz-Pinto, Honorato Ortiz Marrón, and Miguel Pedromingo Kuss
34. The impact of the COVID-19 pandemic during the lockdown and the post-COVID-19 effects on
the family system of children with disabilities
Bekir Fatih Meral
35. The impact of the COVID-19 pandemic on ordinary vaccination programs for very young children: BCG, MMR, poliomyelitis, and beyond
Guilherme Silveira Procianoy and Rita C Silveira
36. Immune responses to SARS-CoV-2 infection and vaccination in children
Zheng Quan Toh, Nadia Mazarakis, and Paul V. Licciardi
37. The impact of the COVID-19 pandemic: How physical fitness changes in children
Eliseo Iglesias-Soler, Jessica Rial-Vázquez, María Rúa-Alonso, Iván Nine, and Iván Clavel
38. The COVID-19 pandemic and children: Impact on physical activity
Olena Yelizarova, Svitlana Hozak, Tetiana Stankevych, Nadiya Polka, Alla Koblianska, Alla Parats, and Olha Ivanovska
39. The COVID-19 pandemic and stress related to schooling
Xue Yang and Kylie K.Y. Chan
40. Suicidal thoughts and behaviors among adolescents during the COVID-19 pandemic
Christina L. Robillard, Alice Shen, and Brianna J. Turner
41. The COVID-19 pandemic: Attending to hand hygiene measures in young people
(a review of different studies)
Anna Espart, Luisa Guitard-Sein Echaluce, Maria Barcenilla-Guitard, Alba Guitard-Quer, and Fernando Barcenilla
42. Child and adolescent COVID-19 vaccination: Trends, hesitancy, and strategies for increasing vaccination
Kimberly H. Nguyen, Lavanya Vasudevan, and Robert A. Bednarczyk
43. Social distancing behavior and mental health in US adolescents during the COVID-19 pandemic
Ming-Te Wang, Christina L. Scanlon, Ashley Sunjae Lee, and Ariana C. Henderson
44. Thrombotic complications in children and adolescents with SARS-CoV-2 infection
Clay T. Cohen, Dalia A. Bashir, and Sarah E. Sartain
45. Features of SARS-CoV-2 infection and vaccination in children: A focus on magnetic resonance imaging of the heart
Łukasz A. Małek
46. SARS-CoV-2 infection and the cytokine levels and pathway in children: An updated narrative
Tsvetelina Velikova and Snezhina Lazova
Section E: Older adults
47. Risk factors related to COVID-19 among older adults
Eva M. Satué-Gracia, Albert del Pozo-Niubo, María-José Forcadell-Peris, Cinta de Diego-Cabanes, Angel Vila-Córcoles, and Francisco M. Martín-Luján
48. Reducing loneliness and social isolation among the elderly during the COVID-19 pandemic
Xiangfei Meng, Muzi Li, and Yingying Su
49. Features and measures of depression in the elderly and the impact of the COVID-19
pandemic: Linking in preexisting mental health
Omar Paccagnella
50. Experiences of disabled older adults in adult day care centers during the COVID-19 pandemic
Takashi Naruse
51. Using single-cell analysis to investigate disease severity in elderly patients with COVID-19
Sherine K. Saber, Ahmed S. Abouhashem, Ahmed A. Elbaz, Sedat Kacar, Kanhaiya Singh, Chandan K. Sen, and Hassan M.E. Azzazy
52. COVID-19 and older adult food practices: A social determinants of health perspective
Sarah L. Francis, Catherine S. Rudolph, and Savannah Schultz
53. Older subjects and immunogenicity of mRNA COVID-19 vaccines
Piotr Seiffert and Dorota Religa
54. Noninvasive respiratory support in octogenarian patients with COVID-19
Federico Lionello, Gabriella Guarnieri, Giovanna Arcaro, Sara Lococo, and Andrea Vianello
Section F: Case studies with mini review
55. Case study: COVID-19 severity in diabetic patients with and without seizure
Budhadev Baral, Kartik Muduli, Shweta Jakhmola, Vaishali Saini, Pratik Kundu, Nikunj Kumar Rout, Shubhransu Patro, Nirmal Kumar Mohakud, and Hem Chandra Jha
56. Case study: Nonpharmaceutical interventions for COVID-19 and their social impact in Japan
Makoto Niwa, Shintaro Sengoku, and Kota Kodama
57. Case study: Factors affecting vaccine uptake—Australian perspectives
Jessica Carter and Erika Borkoles
58. The impact of the COVID-19 pandemic on an older disabled person
Takashi Naruse
59. COVID-19 in the newborn: Clinical course and effects of maternal vaccination in pregnancy
Cinzia Auriti, Chiara Maddaloni, and Domenico Umberto De Rose
Section G: Resources
60. Recommended resources for the international and life course aspects of coronavirus disease 2019 (COVID-19)
Rajkumar Rajendram, Daniel Gyamfi, Vinood B. Patel, and Victor R. Preedy
Linking Neuroscience and Behavior in COVID-19
Preface
Section A: Introductory chapters and setting the scene
1. The historical aspects of the SARS-CoV-2 virus and the ensuing pandemic
Taslima Nasrin, Md Samim Hassan, Arijit Samanta, Mehboob Hoque, and Safdar Ali
2. Different variants of SARS-CoV-2
Arijit Samanta, Md Samim Hassan, Taslima Nasrin, Syed Sahajada Mahafujul Alam, Zarnain Jamil, Harpal S. Buttar, Safdar Ali, and Mehboob Hoque
3. Lateral flow assay for SARS-CoV-2 infection: Uses and limitations
Mirajul Islam, Taslima Nasrin, Arijit Samanta, Safdar Ali, Harpal S. Buttar, and Mehboob Hoque
4. Linking community participation, mobility disabilities, and the COVID-19 pandemic
Kara B. Ayers, Jean P. Hall, and Claire Burdick
5. Influence of the sources used to obtain information on COVID-19 and their impact on mental health
Juan Gómez-Salgado, Juan Jesús García-Iglesias, Regina Allande-Cussó, and Carlos Ruiz-Frutos
Section B: Impact on behavior and psychology
6. The psychological experiences and distress of defined populations in the COVID-19 pandemic: Doctors
Amy Pascoe, Karen Willis, and Natasha Smallwood
7. Impact of COVID-19 on behavior in autism spectrum disorder
Giulia Antolini and Marco Colizzi
8. Prepandemic stressors in mental health responses to the COVID-19 pandemic: Early life adversities and beyond
Xiangfei Meng
9. Compulsive hoarding in the COVID-19 pandemic
Nicole Loren Angelo, Andrea Pozza, Debora Rossi, Ilaria Aicardi, Giulia Chieppa, Isabella Bove, Federica Ragucci, Francesco Iocca, Daniele Pugi, and Donatella Marazziti
10. The psychological experiences and distress in Japan and Sweden during the COVID-19 pandemic
Sayo Hamatani, Anton K€all, Konomi Shoda, and Kazuki Matsumoto
11. The COVID-19 pandemic, mental health, and sleep: Linking depression, anxiety, and perceived
stress
Joana Bücker, Adriane Ribeiro Rosa, and Letícia Sanguinetti Czepielewski
12. The Covid-19 pandemic and the occupational overload of health professionals: Indicators of
burnout
Isabella Lara Machado Silveira, Flávia de Lima Osório, and Sonia Regina Loureiro
13. Neurocognitive sequelae of SARS-CoV-2 infection: Pathogenesis, risk factors, assessment, and implications
Mohammad Nazmus Sakib
14. Acute neurocognitive disorder as a presenting manifestation of COVID-19
Brad Tyson, Leigh Tyson, Sudeshna Ray, and Pinky Agarwal
15. Mental health and the impact of confinement
Lorabi Souhib, David Sánchez-Teruel, Selma Boufellous, and María Auxiliadora Robles-Bello
16. Cannabis use in the COVID-19 pandemic: Changes in different populations and implications
for policy
Adam Zaweel, Isaac Kuk, Soyeon Kim, Bernard Le Foll, and Christine M. Wickens
17. Impact of COVID-19 on mental health in women: Socioeconomic groups and global aspects
Khushi Kumar, Aashni Udani, and Maushmi S. Kumar
18. Quality of life assessment of patients after COVID-19
Eleni Tsimitrea, Paraskevi Siamouti, Konstntinos I. Gourgoulianis, and Evangelos C. Fradelos
19. COVID-19 pandemic and remote working: Toward a new way of working
Ferdinando Toscano and Teresa Galanti
20. Long COVID and its persistence: A focus on mental health
Michael John Dwyer, Massimo Mirandola, and Elda Righi
21. The impact of the COVID-19 pandemic on behavioral and psychological features of vulnerable groups: Patients with multiple sclerosis and their quality of life
Kubra Yeni
Section C: Effects on neurological structures and mechanisms
23. Linking pediatric COVID-19 with basal ganglia and dentate nucleus
Shraddha Sunthwal, Sagar Lad, and Preeti Lad
24. Sensory disorders, neuroinflammation, and COVID-19
Pietro De Luca and Arianna Di Stadio
25. The effects of COVID-19 isolations on nonmotor features of Parkinson’s disease
Santangelo Gabriella and Carmine Vitale
26. Myelitis following COVID-19: The road so far
Cristiana Silva and Sónia Batista
27. The corpus callosum: Effects due to SARS-CoV-2 infection and the mRNA vaccine
Luca Procaccini and Antonio Bernardini
28. Assessing the impact of prenatal SARS-CoV-2 exposure on infants’ neurodevelopment: A comprehensive analysis of current evidence
Fernanda Nava and Vania Aldrete-Cortez
29. Electroencephalographic features with COVID-19
Isabel M. Sáez-Landete, Adriana Gómez-Domínguez, Beatriz Estrella-León, and Alba Díaz-Cid
30. Survivors of COVID-19 and clinical neuropsychological domain characteristics
Pamela E. May-Weeks and Vaishali Phatak
31. Neuroinflammation following SARS-CoV-2 infection
Carlos Alexandre Netto and Marimelia A Porcionatto
32. Functional magnetic resonance imaging and depressive symptoms in subjects with COVID-19
Giulia Cattarinussi, Alessandro Miola, and Fabio Sambataro
33. Impact of COVID-19 on the brain: Antibodies against brain stem antigens
Guglielmo Lucchese, Antje Vogelgesang, Angela Stufano, and Agnes Flöel
34. The kynurenine pathway and role in mental health of post-COVID-19 patients
Melike Kucukkarapinar, Filiz Karadag, and Selcuk Candansayar
Section D: Management, support and treatments
35. Management of brain tumors in the COVID-19 pandemic
Rajesh Balakrishnan, Sharief K. Sidhique, Patricia Sebastian, and Selvamani Backianathan
36. The impact of the COVID-19 pandemic on ischemic stroke management: From hyperacute to chronic phase
Irene Scala, Simone Bellavia, Aldobrando Broccolini, Giovanni Frisullo, Pier Andrea Rizzo, Eleonora Rollo, Giacomo Della Marca, and Valerio Brunetti
37. Long COVID and the potential use of palmitoylethanolamide
Rocco Salvatore Calabro` and Loredana Raciti
38. Cognitive assessments in post-COVID syndrome: A focus on the neuropsychological tests and
protocols
Cristina Delgado-Alonso and Jordi A. Matias-Guiu
39. Supporting individuals with intellectual and developmental disabilities during the COVID-19
pandemic
David Ervin, Melody Jan, Emily J. Johnson, Lin Peters, and Carl Tyler
40. Preserving well-being and quality of life through school-based interventions focused on physical
activity during the COVID-19 pandemic
Alice Masini, Francesco Sanmarchi, and Laura Dallolio
41. Hesitancy in using COVID 19 prevention behaviors among African Americans: Strategies to
build confidence
Jennifer Cunningham Erves, Jamaine Davis, Elizabeth C. Stewart, Vanessa B. Crowther, and Whitney George
42. New strategies for psychological well-being at work
Teresa Galanti and Ferdinando Toscano
43. Mitigating mental health changes with virtual reality technology during Covid-19: A narrative
Muhammad Hizri Hatta, Chong Siew Koon, and Suriati Mohamed Saini
44. Music therapy for patients with neurological disorders during COVID-19 pandemic
Claudia Vinciguerra, Salvatore Iacono, Vincenzo Di Stefano, Valerio Nardone, and Antonio Federico
45. Mental health and the modulating effects of receiving the COVID-19 vaccination
Natsu Sasaki and Norito Kawakami
46. Personalized cognitive behavioral therapy on patients with obesity in COVID-19 pandemic
Riccardo Dalle Grave, Anna Dalle Grave, and Simona Calugi
47. Social anxiety disorder and Covid 19: Treatment with cognitive behavioral therapy
Narendra Nath Samantaray and Sapam Kiran Dolly
48. Burnout during the COVID-19 pandemic: Modulating role of mindfulness
Makiko Sampei and Naho Morisaki
Section E: Case studies with mini review
49. Case study: Evaluation of a long Covid assessment service (LCAS)
Colin R. Martin, Scarlett Maloney, Sarah Fowler, Frances Farnworth, Katie Tyrrell, and Abigail Webb
50. Case study: Navigating youth mental health and addictions care in the context of the COVID-19 pandemic
Roula Markoulakis and Anthony Levitt
51. Case study: Restless leg syndrome associated with COVID-19
Cyprian Popescu
Section F: Resources
52. Recommended resources for linking neuroscience and behavior in coronavirus disease
(COVID-19)
Rajkumar Rajendram, Daniel Gyamfi, Vinood B. Patel, and Victor R. Preedy
Management, Body Systems, and Case Studies in COVID-19
Preface
Section A: Introductory chapters and setting the scene
1. Hand hygiene strategies
Trinidad Montero-Vilchez, Clara-Amanda Ureña-Paniego, Alberto Soto-Moreno, Alejandro Molina-Leyva, and Salvador Arias-Santiago
2. Approved vaccines for the COVID-19 pandemic: Linking in future perspectives
Larissa Moraes dos Santos Fonseca, Katharine Valéria Saraiva Hodel, Vinícius Pinto Costa Rocha, Milena Botelho Pereira Soares, and Bruna Aparecida Souza Machado
3. Molecular methods for SARS-CoV-2 variant detection
Marco Fabiani, Katia Margiotti, Francesca Monaco, Alvaro Mesoraca, and Claudio Giorlandino
Section B: Management
4. Systematic patient assessment for acute respiratory tract ailments (SPARTA): A simple tool to improve outcomes from COVID-19
Rajkumar Rajendram, Naveed Mahmood, Mohammad Ayaz Khan, and Hamdan Al-Jahdali
5. Point of care ultrasound for coronavirus disease 2019: The multiorgan approach to COVID-19
Rajkumar Rajendram
6. COVID-19 in patients with inflammatory bowel diseases: Features and guidelines
Carlos Taxonera and Olga Neva López-García
7. Management of COVID-19 and clinical nutrition
Manola Peverini and Giacomo Barberini
8. The management of head and neck cancer in COVID-19
Jesús Herranz-Larrañeta, Pablo Parente-Arias, Carlos Chiesa-Estomba, and
Miguel Mayo-Yáñez
9. The COVID-19 pandemic: Inventory management and allocation of personal protective
equipment
Tazim Merchant and Mark Sheldon
10. Clinical management in the COVID-19 pandemic: Rheumatic disease
Abdulvahap Kahveci and Şebnem Ataman
11. Managing migraines during the COVID-19 pandemic: An Italian experience
Licia Grazzi, Danilo Antonio Montisano, and Paul Rizzoli
12. Managing acute ischemic stroke in the SARS-CoV-2 pandemic
Adele S. Budiansky, Wesley Rajaleelan, and Tumul Chowdhury
13. Impact of the coronavirus disease 2019 pandemic on patients with hypertension
Kazuo Kobayashi and Kouichi Tamura
14. Neurosurgical trauma management during COVID-19 restrictions
James Zhou, Michael Zhang, and Harminder Singh
15. The COVID-19 pandemic and management of weight gain: Implications for obesity
Sarah R. Barenbaum and Alpana P. Shukla
16. COVID-19 and the management of heart failure using telemedicine
Maria Margarida Andrade, Diogo Cruz, and Marta Afonso Nogueira
Section C: Guidelines for different treatment clinics
17. Guidelines for breast imaging in the COVID-19 pandemic
Daniele Ugo Tari
18. Vaccine-induced (immune) thrombotic thrombocytopenia (VITT): Diagnosis, guidelines,
and reporting
Emmanuel J. Favaloro, Leonardo Pasalic, and Giuseppe Lippi
19. Lung cancer in the era of COVID-19
Shehab Mohamed, Monica Casiraghi, Lorenzo Spaggiari, and Luca Bertolaccini
20. Multisystem inflammatory syndrome in children/pediatric inflammatory multisystem
syndrome: Clinical guidelines
Arthur J. Chang, Ramesh Kordi, and Mark D. Hicar
Section D: Impact on the respiratory system
21. Ground-glass nodules in the lungs of COVID-19 patients
Noel Roig-Marín
22. Cardiothoracic imaging in patients affected by COVID-19
Tommaso D’Angelo, Ludovica R.M. Lanzafame, M. Ludovica Carerj, Antonino Micari, Silvio Mazziotti, and Christian Booz
23. Cystic fibrosis and bronchial epithelial cells in SARS-CoV-2 infection
Anna Lagni, Erica Diani, Davide Gibellini, and Virginia Lotti
24. Biomechanics and mechanobiology of the lung parenchyma following SARS-CoV-2 infection
Béla Suki, András Lorx, and Erzsébet Bartolák-Suki
25. Long noncoding RNA profiling in respiratory specimens from COVID-19 patients
Marta Molinero, Carlos Rodríguez-Muñoz, Silvia Gómez, Ángel Estella, Ferran Barbé, and David de Gonzalo-Calvo
26. COVID-19 and acute pulmonary embolism
Marco Zuin and Gianluca Rigatelli
27. The usefulness of the alveolar-arteriolar gradient during the COVID-19 pandemic
Giuseppe Pipitone, Miriam De Michele, Massimo Sartelli, Francesco Onorato, Claudia Imburgia, Antonio Cascio, and Chiara Iaria
Section E: Effects on cardiovascular and hematological systems
28. Cardiac manifestations of COVID-19: An overview
Naveed Rahman, Mirza H. Ali, Aanchal Sawhney, Apurva Vyas, and Rahul Gupta
29. Limb ischemia and COVID-19
Raffaello Bellosta, Sara Allievi, Luca Attisani, Luca Luzzani, and Matteo Alberto Pegorer
30. Thrombosis and coagulopathy in COVID-19: A new narrative
Alejandro Lazo-Langner and Mateo Porres-Aguilar
31. COVID-19 myocarditis: Features of echocardiography
Antonello D’Andrea, Dario Fabiani, Francesco Sabatella, Carmen Del Giudice, Luigi Cante, Adriano Caputo, Stefano Palermi, Francesco Giallauria, and Vincenzo Russo
32. COVID-19 lockdown and impact on arrhythmias
Valentino Ducceschi and Giovanni Domenico Ciriello
33. Cardiometabolic disease and COVID-19: A new narrative
Mohamad B. Taha, Bharat Narasimhan, Eleonora Avenatti, Aayush Shah, and Wilbert S. Aronow
34. Postrecovery COVID-19 and interlinking diabetes and cardiovascular events
Giuseppe Seghieri
35. COVID-19 patients and extracorporeal membrane oxygenation
Mario Castano, Pasquale Maiorano, Laura Castillo, Gregorio Laguna, Guillermo Muniz-Albaiceta, Victor Sagredo, Elio Marin-Gutierrez, and Javier Gualis
36. Sars-CoV-2 infection in different hematological patients
Saša Anžej Doma
Section F: Effects on body systems
37. Dermatological reactions associated with personal protective equipment use during
the COVID-19 pandemic
Nicholas Herzer, Fletcher G. Young, Chrystie Nguyen, Aniruddha Singh, and Doug McElroy
38. Hemodialysis patients, effects of infections by SARS-CoV-2 and vaccine response
Diana Rodríguez-Espinosa, Elena Cuadrado-Payán, and José Jesús Broseta
39. Coinfections with COVID-19: A focus on tuberculosis (TB)
Chijioke Obiwe Onyeani, Dimo Chisom Precious, Emmanuel Ebuka Elebesunu, Malachy Ekene Ezema, Samuel Ogunsola, and Ademola Aiyenuro
40. Patients with autoimmune liver disease and the impact of Sars-COV-2 infection
Annarosa Floreani, Sara De Martin, and Nora Cazzagon
41. COVID-19 severity and nonalcoholic fatty liver disease
Nina Vrsaljko, Branimir Gjurašin, and Neven Papić
42. Changes in obesity and diabetes severity during the COVID-19 pandemic at Virginia
Commonwealth University health system
Asmaa M. Namoos, Vanessa Sheppard, NourEldin Abosamak, Martin Lavallee, Rana Ramadan, Estelle Eyob, Chen Wang, and Tamas S. Gal
43. The diabetic patient and concomitant conditions rhinoorbital-cerebral mucormycosis
and COVID-19
Caglar Eker
44. Tissue location of SARS-CoV-2 RNA: A focus on bone and implications for skeletal health
Edoardo Guazzoni, Luigi di Filippo, Alberto Castelli, Andrea Giustina, and Federico Grassi
45. Linking between gastrointestinal tract effects of COVID-19 and tryptophan metabolism
Yoshihiro Yokoyama and Hiroshi Nakase
46. Organ damage in SARS-CoV-2 infection in children: A focus on acute kidney injury
Girish Chandra Bhatt, Yogendra Singh Yadav, and Tanya Sharma
47. Obesity, COVID-19 severity, and mortality
Riecha Joshi, Aarushi Sudan, Akshat Banga, Rahul Kashyap, and Vikas Bansal
48. Upper and lower gastrointestinal symptoms and manifestations of COVID-19
Brittany Woods, Priyal Mehta, Gowthami Sai Kogilathota Jagirdhar, Rahul Kashyap, and Vikas Bansal
49. The COVID-19 survivors: Impact on skeletal muscle strength
Renata Gonçalves Mendes, Alessandro Domingues Heubel, Naiara Tais Leonardi, Stephanie Nogueira Linares, Vanessa Teixeira do Amaral, and Emmanuel Gomes Ciolac
Section G: Case studies with mini review
50. A case report: COVID-19 meningoencephalitis and intracranial hemorrhage
Mohammad Alolama, Anas Rashid, and Debora Garozzo
51. Case study: Oral mucosal lesions in patients with COVID-19
Juliana Amorim dos Santos, Rainier Luiz Carvalho da Silva, and Eliete Neves Silva Guerra
52. Case study: COVID-19 pneumonia presented with cavitary lesions
Bahadır M. Berktaş
53. Case study: Optic neuritis in SARS-CoV-2 infection
Md Moshiur Rahman
Section H: Resources
54. Recommended resources relevant to the body systems involvement
and management of COVID-19
Rajkumar Rajendram, Daniel Gyamfi, Vinood B. Patel, and Victor R. Preedy
Product details
Product details
- Edition: 1
- Latest edition
- Published: June 1, 2024
- Language: English
About the editors
About the editors
RR
Rajkumar Rajendram
Dr Rajkumar Rajendram is a clinician scientist with a focus on internal medicine, anaesthesia, intensive care and peri-operative medicine. He graduated with distinctions from Guy’s, King’s and St. Thomas Medical School, King’s College London in 2001. As an undergraduate he was awarded several prizes, merits and distinctions in pre-clinical and clinical subjects.
Dr Rajendram began his post-graduate medical training in general medicine and intensive care in Oxford. He attained membership of the Royal College of Physicians (MRCP) in 2004 and completed specialist training in acute and general medicine in Oxford in 2010. Dr Rajendram subsequently practiced as a Consultant in Acute General Medicine at the John Radcliffe Hospital, Oxford.
Dr Rajendram also trained in anaesthesia and intensive care in London and was awarded a fellowship of the Royal College of Anaesthetists (FRCA) in 2009. He completed advanced training in regional anaesthesia and intensive care. He was awarded a fellowship of the Faculty of Intensive Care Medicine (FFICM) in 2013 and obtained the European diploma of intensive care medicine (EDIC) in 2014. He then moved to the Royal Free London Hospitals as a Consultant in Intensive Care, Anaesthesia and Peri-operative Medicine. He has been a fellow of the Royal College of Physicians of Edinburgh (FRCP Edin) and the Royal College of Physicians of London (FRCP Lond) since 2017 and 2019 respectively. He is currently a Consultant in Internal Medicine at King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi Arabia.
Dr Rajendram’s focus on improving outcomes from Coronavirus Disease 2019 (COVID-19) has involved research on point of care ultrasound and phenotypes of COVID-19. Dr Rajendram also recognises that nutritional support is a fundamental aspect of medical care. This is particularly important for patients with COVID-19. As a clinician scientist he has therefore devoted significant time and effort into nutritional science research and education. He is an affiliated member of the Nutritional Sciences Research Division of King’s College London and has published over 400 textbook chapters, review articles, peer-reviewed papers and abstracts.
Affiliations and expertise
Consultant, Medical Protocol Department, King Abdulaziz Medical City, Ministry of National Guard Heath Affairs, Riyadh, Saudi ArabiaVP
Victor R. Preedy
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.
Affiliations and expertise
Professor, Department of Clinical Biochemistry, King’s College Hospital, London, UK; Emeritus Professor, Faculty of Life Sciences and Medicine, King’s College London, UK; Visiting Professor, University of Hull, UKVP
Vinood Patel
Vinood B. Patel, BSc, PhD, FRSC, is currently Professor in Clinical Biochemistry at the University of Westminster. In 2014 Dr Patel was elected as a Fellow to The Royal Society of Chemistry. Dr Patel graduated from the University of Portsmouth with a degree in Pharmacology and completed his PhD in protein metabolism from King’s College London in 1997. His postdoctoral work was carried out at Wake Forest University Baptist Medical School, NC, USA studying structural-functional alterations to mitochondrial ribosomes, where he developed novel techniques to characterize their biophysical properties. Research is being undertaken to study the role of nutrients, antioxidants, phytochemicals, iron, alcohol and fatty acids in the pathophysiology of liver disease. Other areas of interest are identifying new biomarkers that can be used for the diagnosis and prognosis of disease and understanding mitochondrial oxidative stress in neurological disorders and iron dysregulation in diabetes. Dr Patel is a nationally and internationally recognized researcher and has several edited biomedical books related to the use or investigation of active agents or components. These books include The Handbook of Nutrition, Diet, and Epigenetics, Branched Chain Amino Acids in Clinical Nutrition, Cancer: Oxidative Stress and Dietary Antioxidants, Toxicology: Oxidative Stress and Dietary Antioxidants, Molecular Nutrition: Vitamins, The Neuroscience of Pain, Cognitive Behavioural Therapy. He is Editor of the ten-volume series Biomarkers in Disease: Methods, Discoveries and Applications
Affiliations and expertise
Professor, University Westminster, UKCM
Colin R. Martin
Colin R. Martin RN, BSc, MSc, PhD, MBA, YCAP, FHEA, C.Psychol, AFBPsS, C.Sci is Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director of the Institute of Health and Wellbeing at the University of Suffolk, UK. He is a Chartered Health Psychologist and a Chartered Scientist. He also trained in analytical biochemistry, this aspect reflecting the psychobiological focus of much of his research within mental health. He has published or has in press well over 300 research papers and book chapters. He is a keen book author and editor having written and/or edited more than 50 books. These outputs include the prophetic insight into the treatment of neurological disease, Handbook of Behavior, Food and Nutrition (2011), Nanomedicine and the Nervous System (2012), Oxidative Stress and Dietary Antioxidants in Neurological Disease (2020), Zika Virus Impact, Diagnosis, Control and Models (2021), Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior and Diet (2021), Diagnosis and Treatment of Spinal Cord Injury (2022), The Neurobiology, Physiology, and Psychology of Pain (2022) and The Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging (2023). Professor Martin is particularly interested in all aspects of the relationship between underlying physiological substrates and behavior, particularly in how these relationships manifest in both acute and chronic psychiatric disorder. He has published original research germane to significant mental health disorders including the areas of schizophrenia, anxiety, depression, self-esteem, alcohol and drug dependency, high secure forensic mental health and personality disorder. He has a keen interest in the impact of postviral illness and is actively involved in clinical research post-Covid pandemic and in particular, the impact of Long Covid on psychological, neurological, physiological and social functioning. He is involved in collaborative International research with many European and Non-European countries.
Affiliations and expertise
Visiting Professor of Perinatal Wellbeing, Institute for Health and Wellbeing, University of Suffolk, Ipswich, UK