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    • Methods in iPSC Technology

      • 1st Edition
      • June 2, 2021
      • Alexander Birbrair
      • English
      • Paperback
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      • eBook
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      The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Methods in iPSC Technology, Volume 9 addresses the different methods used for induced pluripotent stem cell (iPSC) formation, maintenance, expansion, and differentiation. The ability to reprogram different cell types to iPSCs offers an opportunity to generate pluripotent patient-specific cell lines that can help in the understanding of multiple human disorders. This volume addresses a variety of current methods used in the generation and manipulation of iPSCs, such as magnetic nanoparticles, piggyBac vectors, lentiviral vectors, bioscaffolds, somatic cell nuclear transfer, CRISPR/Cas9, bacteria, and much more. This volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and organ transplantation and is contributed by world-renowned authors in the field.

    • Mathematica by Example

      • 6th Edition
      • June 1, 2021
      • Martha L. Abell + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 4 1 6 3 9
      • eBook
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      Mathematica by Example, Sixth Edition is an essential resource for the Mathematica user, providing step-by-step instructions on achieving results from this powerful software tool. The book fully accounts for the changes to functionality and visualization capabilities and accomodates the full array of new extensions in the types of data and problems that Mathematica can immediately handle, including cloud services and systems, geographic and geometric computation, dynamic visualization, interactive applications and other improvements. It is an ideal text for scientific students, researchers, and aspiring programmers seeking further understanding of Mathematica. Written by seasoned practitioners with a view to practical implementation and problem-solving, the book's pedagogy is delivered clearly and without jargon using representative biological, physical and engineering problems. Code is provided on an ancillary website to support the use of Mathematica across diverse applications and subject areas.

    • Gigantism and Acromegaly

      • 1st Edition
      • June 1, 2021
      • Constantine A. Stratakis
      • English
      • Paperback
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      • eBook
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      Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim’s appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies.

    • Lanzkowsky's Manual of Pediatric Hematology and Oncology

      • 7th Edition
      • June 1, 2021
      • Jonathan D. Fish + 2 more
      • English
      • Hardback
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      • eBook
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      • eBook
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      Lanzkowsky’s Manual of Pediatric Hematology and Oncology, Seventh Edition remains the go-to clinical manual for the treatment and management of childhood cancers and blood disorders. It is a comprehensive book on patient management, replete with algorithms and flow diagrams, and includes a new section on vascular anomalies. Reflecting the considerable advances in the treatment and management of hematologic and oncologic diseases in children, the seventh edition of this successful clinical manual is entirely updated to incorporate all current treatment protocols, new drugs, and management approaches. Its concise and easy-to-read format, again, enables readers to make accurate diagnoses and treatment decisions without having to reference larger medical textbooks.

    • Assessments, Treatments and Modeling in Aging and Neurological Disease

      • 1st Edition
      • June 1, 2021
      • Colin R. Martin + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 1 8 0 0 0 6
      • eBook
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      Assessments, Treatments and Modeling in Aging and Neurological Disease: The Neuroscience of Aging is a comprehensive reference on the diagnosis and management of neurological aging and associated disorders. The book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the interactions between genetics, epigenetics and other micro-environmental processes. It also examines pharmacological and non-pharmacological interventions of age-related conditions that affect the brain, including Alzheimer’s, stroke and multiple sclerosis.

    • Factors Affecting Neurological Aging

      • 1st Edition
      • June 1, 2021
      • Colin R. Martin + 2 more
      • English
      • Hardback
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      • eBook
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      Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurological aging. Finally, this comprehensive resource examines the use of animal modeling of aging and neurological disease.

    • Amphibian Models of Development and Disease

      • 1st Edition
      • Volume 145
      • May 30, 2021
      • English
      • Hardback
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      • eBook
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      Amphibian Models of Development and Disease, Volume 145 in the Current Topics in Developmental Biology series, highlights new advances in the field written by an international board of experts. New chapters in this release include Building a ciliated epithelium: Transcriptional regulation and radial intercalation of multiciliated cells, Biomechanics of Amphibian Morphogenesis, Planar cell polarity during neural tube closure, Xenopus neural crest and its relevance to human disease, Endoderm organogenesis, From egg to embryo in marsupial frogs, Evo-devo lessons from the analysis of Xenopus genomes, Transcriptional regulation during zygotic genome activation, Proteomics and metabolomics for cell lineage analysis in frog embryos, and more.

    • Ion Channels: Channel Biochemistry, Reconstitution, and Function

      • 1st Edition
      • Volume 652
      • May 29, 2021
      • English
      • Hardback
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      • eBook
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      Ion Channels Part A, Volume 651 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of new developments on the topic. Each chapter is written by an international board of authors.

    • TeleStroke

      • 1st Edition
      • May 29, 2021
      • Latisha Katie Sharma
      • English
      • Paperback
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      • eBook
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      Telestroke helps readers develop a deeper understanding on how to utilize telestroke in clinical practice, a key step in providing optimal treatment and management to those with geographical and social/economic disparities. The book discusses how to provide accurate and fast revascularization for patients with acute ischemic stroke and how to continue remote care of patients. It also reviews underlying stroke etiology, interpretation and assessment of stroke diagnostic tools/teleradiology, complications of care, discusses targeted, secondary preventative therapies and covers telerehabilitation, outpatient follow-up and clinical trial engagement.

    • iPSCs for Studying Infectious Diseases

      • 1st Edition
      • May 29, 2021
      • Alexander Birbrair
      • English
      • Paperback
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      • eBook
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      The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs for Studying Infectious Diseases, Volume 8 addresses how important induced pluripotent stems cells are and how can they can help treat certain infectious diseases. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different infectious diseases, such as corona virus, coxsackievirus, salmonella infection, influenza virus and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field.

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