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Elsevier

Academic Press

  • Roadmap to Successful Digital Health Ecosystems

    A Global Perspective
    • 1st Edition
    • Evelyn J.S. Hovenga AM + 1 more
    • English
    Roadmap to Successful Digital Health Ecosystems: A Global Perspective presents evidence-based solutions found on adopting open platforms, standard information models, technology neutral data repositories, and computable clinical data and knowledge (ontologies, terminologies, content models, process models, and guidelines), resulting in improved patient, organizational, and global health outcomes. The book helps engaging countries and stakeholders take action and commit to a digital health strategy, create a global environment and processes that will facilitate and induce collaboration, develop processes for monitoring and evaluating national digital health strategies, and enable learnings to be shared in support of WHO’s global strategy for digital health. The book explains different perspectives and local environments for digital health implementation, including data/information and technology governance, secondary data use, need for effective data interpretation, costly adverse events, models of care, HR management, workforce planning, system connectivity, data sharing and linking, small and big data, change management, and future vision. All proposed solutions are based on real-world scientific, social, and political evidence.

  • Delay-Doppler Communications

    Principles and Applications
    • 1st Edition
    • Yi Hong + 2 more
    • English
    Orthogonal Frequency Division Multiplexing (OFDM) has been the waveform of choice for most wireless communications systems in the past 25 years. This book addresses the “what comes next?” question by presenting the recently proposed waveform known as Orthogonal Time-Frequency-Space (OTFS), which offers a better alternative for high-mobility environments. The OTFS waveform is based on the idea that the mobile wireless channels can be effectively modelled in the delay-Doppler domain. This domain provides a sparse representation closely resembling the physical geometry of the wireless channel. The key physical parameters such as relative velocity and distance of the reflectors with respect to the receiver can be considered roughly invariant in the duration of a frame up to a few milliseconds. This enables the information symbols encoded in the delay-Doppler domain to experience a flat fading channel even when they are affected by multiple Doppler shifts present in high-mobility environments. Delay-Doppler Communications: Principles and Applications covers the fundamental concepts and the underlying principles of delay-Doppler communications. Readers familiar with OFDM will be able to quickly understand the key differences in delay-Doppler domain waveforms that can overcome some of the challenges of high-mobility communications. For the broader readership with a basic knowledge of wireless communications principles, the book provides sufficient background to be self-contained. The book provides a general overview of future research directions and discusses a range of applications of delay-Doppler domain signal processing.

  • The Lymphatic System in Colorectal Cancer

    Basic Concepts, Pathology, Imaging, and Treatment Perspectives
    • 1st Edition
    • Wim Ceelen
    • English
    The Lymphatic System in Colorectal Cancer: Basic Concepts, Pathology, Imaging, and Treatment Perspectives provides an in-depth overview on the role of the lymphatic system in the pathogenesis and treatment of colorectal cancer. This is the first book to provide a comprehensive, multidisciplinary approach to the lymphatic system in colorectal cancer, with topics ranging from cancer biology and mathematical modeling to surgical approaches and novel imaging techniques. This book is valuable for cancer researchers, oncologists and anyone interested in the biology and treatment of colorectal cancer. Bringing together internationally renowned experts, the book's chapters encompass relevant content to help readers understand complex subjects. Lymphatic spread is one of the hallmarks of locally advanced colorectal cancer that adversely affects prognosis. Nevertheless, the molecular pathogenesis, dynamics and prognostic significance of lymphatic spread remain poorly understood. At the same time, novel surgical approaches such as complete mesocolic excision and sentinel node identification are being introduced, but their value remains uncertain.

  • Reproductive and Developmental Toxicology

    • 3rd Edition
    • Ramesh C. Gupta
    • English
    **Selected for Doody’s Core Titles® 2024 in Toxicology**Reproduc... and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, and metals, among others. In addition, it is the only resource to include reproductive and developmental toxicity in domestic animals, fish and wildlifeWith a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages. Completely revised and updated to include the most recent developments in the field, this book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists and teratologists from academia, industry and regulatory agencies.

  • MCB: CAR T Cells: Development, Characterization and Applications

    • 1st Edition
    • Volume 167
    • Lorenzo Galluzzi + 1 more
    • English
    MCB: CAR T Cells: Development, Characterization and Applications, Volume 167 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including High-efficiency of genetic modification using CRISPR/Cpf1 system for engineered CAR T-cell therapy, Determination of the Biodistribution of Chimeric Antigen Receptor-Modified T Cells against CD19 in NSG Mice, Generation of CAR-T cells using lentiviral vectors, Generation of CAR T-cells using γ-retroviral vector, Flow cytometry detection and quantification of CAR T cells into solid tumors, Evaluation of CAR-T Cell Cytotoxicity: Real-Time Impedance-Based Analysis, and much more.

  • Machine Learning for Future Fiber-Optic Communication Systems

    • 1st Edition
    • Alan Pak Tao Lau + 1 more
    • English
    Machine Learning for Future Fiber-Optic Communication Systems provides a comprehensive and in-depth treatment of machine learning concepts and techniques applied to key areas within optical communications and networking, reflecting the state-of-the-art research and industrial practices. The book gives knowledge and insights into the role machine learning-based mechanisms will soon play in the future realization of intelligent optical network infrastructures that can manage and monitor themselves, diagnose and resolve problems, and provide intelligent and efficient services to the end users. With up-to-date coverage and extensive treatment of various important topics related to machine learning for fiber-optic communication systems, this book is an invaluable reference for photonics researchers and engineers. It is also a very suitable text for graduate students interested in ML-based signal processing and networking.

  • Ensuring Global Food Safety

    Exploring Global Harmonization
    • 2nd Edition
    • Aleksandra Martinovic + 2 more
    • English
    Ensuring Global Food Safety: Exploring Global Harmonization, Second Edition, examines the policies and practices of food law which remain top contributors to food waste. This fully revised and updated edition offers a rational and multifaceted approach to the science-based issue of "what is safe for consumption?" and how creating a globally acceptable framework of microbiological, toxicological and nutritional standards can contribute to the alleviation of hunger and food insecurity in the world. Currently, many laws and regulations are so stringent that healthy food is destroyed based on scientifically incorrect information upon which laws and regulations are based. This book illuminates these issues, offering guidelines for moving toward a scientifically sound approach to food safety regulation that can also improve food security without putting consumers at risk.

  • Multi-Objective Combinatorial Optimization Problems and Solution Methods

    • 1st Edition
    • Mehdi Toloo + 2 more
    • English
    Multi-Objective Combinatorial Optimization Problems and Solution Methods discusses the results of a recent multi-objective combinatorial optimization achievement that considered metaheuristic, mathematical programming, heuristic, hyper heuristic and hybrid approaches. In other words, the book presents various multi-objective combinatorial optimization issues that may benefit from different methods in theory and practice. Combinatorial optimization problems appear in a wide range of applications in operations research, engineering, biological sciences and computer science, hence many optimization approaches have been developed that link the discrete universe to the continuous universe through geometric, analytic and algebraic techniques. This book covers this important topic as computational optimization has become increasingly popular as design optimization and its applications in engineering and industry have become ever more important due to more stringent design requirements in modern engineering practice.

  • Microbial Syntrophy-mediated Eco-enterprising

    • 1st Edition
    • Raghvendra Pratap Singh + 3 more
    • English
    Microbial Syntrophy-Mediated Eco-enterprising summarizes and reviews possible microbial applications for eco-industrial sustainability. The book emphasizes a wide spectrum of experimental and theoretical contributions from eminent researchers in the field. In 13 chapters, there is a focus on the microbial intrusions for remediating sites by accumulated pesticides, heavy metals, polyaromatic hydrocarbons, and other industrial effluents. Moreover, the potentiality and key mechanisms used by microorganisms for sustainable environmental management and their prospects are also considered in this new release. The term syntrophy for nutritional interdependence is often used in microbiology to describe the symbiotic relationship between bacterial species. Understanding such interactions can be of considerable interest when we come to manipulate microbes to our own benefit, such as by disrupting pathogenic communities with antibiotics or by promoting efficiency in communities that produce energy or break down waste.

  • Practical Stress Management

    A Comprehensive Workbook
    • 8th Edition
    • John A. Romas + 1 more
    • English
    Practical Stress Management, Eighth Edition emphasizes a positive approach to stress management, covering topics such as relaxation techniques, coping with anxiety, managing anger, communication skills, exercise and nutrition. In this edition, the authors cover the latest advances in stress management, as well as stress related to the use of technology in education. The context of disasters, such as the COVID-19 pandemic, is also incorporated throughout. The workbook describes some of the surreptitious meditation techniques from India not described before in any text. Worksheets and Thoughts for Reflection boxes help users determine their own level of stress to apply effective stress management techniques.

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