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Elsevier

Academic Press

  • Multi-Objective Combinatorial Optimization Problems and Solution Methods

    • 1st Edition
    • Mehdi Toloo + 2 more
    • English
    Multi-Objective Combinatorial Optimization Problems and Solution Methods discusses the results of a recent multi-objective combinatorial optimization achievement that considered metaheuristic, mathematical programming, heuristic, hyper heuristic and hybrid approaches. In other words, the book presents various multi-objective combinatorial optimization issues that may benefit from different methods in theory and practice. Combinatorial optimization problems appear in a wide range of applications in operations research, engineering, biological sciences and computer science, hence many optimization approaches have been developed that link the discrete universe to the continuous universe through geometric, analytic and algebraic techniques. This book covers this important topic as computational optimization has become increasingly popular as design optimization and its applications in engineering and industry have become ever more important due to more stringent design requirements in modern engineering practice.

  • Environmental Contaminants and Medicinal Plants Action on Female Reproduction

    • 1st Edition
    • Alexander V. Sirotkin + 1 more
    • English
    Environmental Contaminants and Medicinal Plants Action on Female Reproduction discusses the problem of environmental pollution, medicinal and food plants, and their impact on reproduction. The book describes the mechanisms of environmental contaminants' action, outlines the key causes of their harmful impact on reproduction, and explores what regulatory substances and processes should be targeted due to the negative effect of pollutants on reproduction. Furthermore, it describes the provenance, properties, physiological and therapeutic effects, and possible areas of application of the known medicinal and functional food plants and their constituents with a focus on female reproductive processes. This book will be a useful resource for reproductive biologists, specialists in assisted reproduction, animal production and phytotherapy, toxicologists, pharmacologists, pharmaceutical scientists, endocrinologists, medicinal and natural product chemists, nutritionists and others engaged in the study of environmental contaminants and medicinal and functional food plants.

  • Introduction to Business Analytics Using Simulation

    • 2nd Edition
    • Jonathan P. Pinder
    • English
    Introduction to Business Analytics Using Simulation, Second Edition employs an innovative strategy to teach business analytics. The book uses simulation modeling and analysis as mechanisms to introduce and link predictive and prescriptive modeling. Because managers can't fully assess what will happen in the future, but must still make decisions, the book treats uncertainty as an essential element in decision-making. Its use of simulation gives readers a superior way of analyzing past data, understanding an uncertain future, and optimizing results to select the best decision. With its focus on uncertainty and variability, this book provides a comprehensive foundation for business analytics. Students will gain a better understanding of fundamental statistical concepts that are essential to marketing research, Six-Sigma, financial analysis, and business analytics.

  • Microneedles

    • 1st Edition
    • Kevin Ita
    • English
    Microneedles explores the design, fabrication and use of microneedles for drug and vaccine delivery. This book discusses the contemporary status of the field, describing several areas in detail, including the distinct types of microneedles (dissolving, solid, coted, hollow and hydrogel-forming). The anatomy of the eye is also described to facilitate an understanding of microneedle-assisted ocular drug delivery. Finally, the book provides a detailed discussion of microneedle use in the field of diagnostics, with a chapter dedicated to the mathematical modeling of microneedle-mediated drug delivery. As microneedles can be used by research scientists in academia and in industry, this book will be ideal for regulatory scientists and graduate students who find the topic relevant to their area of study.

  • Allosteric Modulation of G Protein-Coupled Receptors

    • 1st Edition
    • Robert Laprairie
    • English
    Allosteric Modulation of G Protein-Coupled Receptors reviews fundamental information on G protein-coupled receptors (GPCRs) and allosteric modulation, presenting original research in the area and collectively providing a comprehensive description of key issues in GPCR allosteric modulation. The book provides background on core concepts of molecular pharmacology while also introducing the most important advances and studies in the area. It also discusses key methodologies. This is an essential book for researchers and advanced students engaged in pharmacology, toxicology and pharmaceutical sciences training and research. Many of the GPCR-targeted drugs released in the past decade have specifically worked via allosteric mechanisms. Unlike direct orthosteric-acting compounds that occupy a similar receptor site to that of endogenous ligands, allosteric modulators alter GPCR-dependent signaling at a site apart from the endogenous ligand. Recent methodological and analytical advances have greatly improved our ability to understand the signaling mechanisms of GPCRs. We now know that allostery is a common regulatory mechanism for all GPCRs and not – as we once believed – unique to a few receptor subfamilies.

  • Pharmacokinetics and Toxicokinetic Considerations - Vol II

    • 1st Edition
    • Rakesh K. Tekade
    • English
    Pharmacokinetics and Toxicokinetic Considerations explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research. As part of the Advances in Pharmaceutical Product Development and Research series, the book provides expert literature on dose, dosage regimen and dose adjustment, medication errors, and approaches for its prevention, the concept of pharmacotherapy, and managed care in clinical interventions. It expounds on strategies to revamp the pharmacokinetics of the drug and the factors affecting the stability of drugs and their metabolites in biological matrices. Finally, the book offers focused elaborations on various bioanalytical methods for bioavailability and bioequivalence assessment and integrates the wide-ranging principles and concepts shared by toxicokinetics and pharmacodynamics as mutual crosstalk rather than isolated observations. It will be helpful to researchers and advanced students working in the pharmaceutical, cosmetics, biotechnology, food, and related industries including toxicologists, pharmacists, and pharmacologists.

  • Advances in Computers

    • 1st Edition
    • Volume 124
    • Suyel Namasudra
    • English
    Advances in Computers, Volume 124 presents updates on innovations in computer hardware, software, theory, design and applications, with this updated volume including new chapters on Traffic-Load-Aware Virtual Channel Power-gating in Network-on-Chips, An Efficient DVS Scheme for On-chip Networks, A Power-Performance Balanced Network-on-Chip for Mixed CPU-GPU Systems, Routerless Networks-on-Chip, Routing Algorithm Design for Power- and Temperature-Aware NoCs, Approximate Communication for Energy-Efficient Network-on-Chip, Power-Efficient NoC Design by Partial Topology Reconfiguration, The Design of a Deflection-based Energy-efficient On-chip Network, and Power-Gating in Networks-on-Chip.

  • Deep Learning for Robot Perception and Cognition

    • 1st Edition
    • Alexandros Iosifidis + 1 more
    • English
    Deep Learning for Robot Perception and Cognition introduces a broad range of topics and methods in deep learning for robot perception and cognition together with end-to-end methodologies. The book provides the conceptual and mathematical background needed for approaching a large number of robot perception and cognition tasks from an end-to-end learning point-of-view. The book is suitable for students, university and industry researchers and practitioners in Robotic Vision, Intelligent Control, Mechatronics, Deep Learning, Robotic Perception and Cognition tasks.

  • Artificial Intelligence-Based Brain-Computer Interface

    • 1st Edition
    • Varun Bajaj + 1 more
    • English
    Artificial Intelligence-Based Brain Computer Interface provides concepts of AI for the modeling of non-invasive modalities of medical signals such as EEG, MRI and FMRI. These modalities and their AI-based analysis are employed in BCI and related applications. The book emphasizes the real challenges in non-invasive input due to the complex nature of the human brain and for a variety of applications for analysis, classification and identification of different mental states. Each chapter starts with a description of a non-invasive input example and the need and motivation of the associated AI methods, along with discussions to connect the technology through BCI. Major topics include different AI methods/techniques such as Deep Neural Networks and Machine Learning algorithms for different non-invasive modalities such as EEG, MRI, FMRI for improving the diagnosis and prognosis of numerous disorders of the nervous system, cardiovascular system, musculoskeletal system, respiratory system and various organs of the body. The book also covers applications of AI in the management of chronic conditions, databases, and in the delivery of health services.

  • Bacterial Bioflocculant for Multifunctional Features

    • 1st Edition
    • S. Sivaramakrishnan + 1 more
    • English
    Bacterial Bioflocculant for Multifunctional Features highlights research findings on the production and characterization of self-assembling bioflocculant from bacterial consortium (encompassing Bacillus subtilis, Enterococcus faecalis and Proteus mirabilis). The book describes the various high-throughput techniques for characterization of wastewater at microbiological and molecular level. Sections cover pharmaceutical compounds, macromolecular compounds and other contaminants, the biotoxicity exhibited cellular and nuclear abnormalities in the zebra fish, and high-throughput techniques used for evaluating the flocculating efficiency of the bacterial bioflocculant to remove the contaminants in different other applications. Bacterial Bioflocculant for Multifunctional Features will help users undertake further advanced research in bacterial bioflocculant for bioremediation technology and environmental prospectives. In addition, it will also inspire readers to understand bioflocculation and its functions.

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