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Elsevier

Academic Press

  • Smart and Sustainable Healthcare Systems

    From Algorithms to Patient Outcomes
    • 1st Edition
    • Shivi Sharma + 3 more
    • English
    Smart and Sustainable Healthcare Systems: From Algorithms to Patient Outcomes addresses the transformative evolution in healthcare driven by artificial intelligence, machine learning, telemedicine, and digital health technologies. This reference responds to the growing need for sustainable, personalized, and efficient healthcare delivery by bridging technical innovation with clinical application across diverse medical and engineering disciplines. The content spans intelligent decision support systems, IoT and wearable technologies, secure electronic medical records, telemedicine solutions, and automation in diagnostics and treatment. The book includes detailed chapters on AI in clinical pathways, predictive healthcare analytics, brain tumor classification, and sustainable telehealth innovations, complemented by real-world case studies and future outlooks. This reference benefits researchers, healthcare engineers, clinicians, and policymakers by providing in-depth exploration of emerging technologies, challenges, and practical solutions in Healthcare 4.0. It promotes sustainable healthcare practices, ethical AI use, and advances in telemedicine, equipping professionals with knowledge to design and implement intelligent healthcare systems that enhance patient care and resource efficiency.

  • Enzymology in Drug Discovery

    • 1st Edition
    • Volume 747
    • English
    This volume is focused on the application of enzymology to drug discovery, with the overarching objective of introducing the general audience to the important role that enzymology plays in modern, molecular targeted drug discovery. The volume opens with a chapter on the role of enzymes in normal human physiology and the causal role played by aberrant enzyme activity in various disease state. A second chapter provides a comprehensive review of inhibition modalities for therapeutic enzyme inhibitors. From there the volume is composed of chapters that cover two general categories of information: (1) methodologies for studying enzyme-ligand interactions and (2) case studies of molecular targeted drug discovery against specific enzyme targets. Chapters within the first category cover methods such as assay design, the role of structural biology in drug optimization, analysis of slow and tight binding inhibitors, enzyme-inhibitor complex dynamics, and covalent enzyme inactivators. The second category includes case studies of therapeutic inhibitors of various enzyme target classes: proteases, methyltransferases, histone demethylases, helicases, nucleic acid processing enzymes, kinesin motor proteins, and cytochrome P450s. Finally, a chapter is also devoted to therapeutic replacement or repair of defective enzymes.

  • Building Better Relationships for Clinical Success and Personal Growth

    Behavioral Artistry
    • 1st Edition
    • Justin B Leaf + 2 more
    • English
    Building Better Relationships for Clinical Success and Personal Growth: Behavioral Artistry examines the transformative realm of Behavioral Artistry (BA), unveiling seven core skills that enhance individual efficacy. Rooted in the academic literature of behavioral analysis, these traits encompass a sense of humor, affinity for people, celebration of small victories, persistence, optimism, objectivity, and tenacity. This reader-friendly approach, devoid of technical jargon, ensures accessibility for a diverse audience. Offering a unique training curriculum, real-life scenarios, and application strategies, this book is not merely informative but also a practical guide to fostering job satisfaction and success in high-turnover fields.As a valuable resource for all clinical professionals, this book equips readers with the tools necessary for personal and professional fulfillment.

  • Insights from Educational Neuroscience and Serious Games in Math Learning

    • 1st Edition
    • Flávia H. Santos + 1 more
    • English
    Insights from Educational Neuroscience and Serious Games in Math Learning offers a compelling exploration of how mathematics learning develops through the dynamic interaction of brain development, cognition, emotion, language, environment, and technology. Drawing on neuroscience, psychology, education, and game-based learning research, the book explores how innovative technologies can improve achievement, engagement, and inclusion in mathematics education while addressing key challenges in developing and implementing effective serious games and emerging technologies for mathematics learning. With contributions from leading researchers and practitioners from around the world, each chapter presents complex ideas in an accessible and engaging way. The first section explores the relationships between mathematics learning and key factors, including executive functions, metacognition, spatial cognition, affective regulation, mathematics anxiety, and developmental dyscalculia. The second section examines the educational potential of digital games, artificial intelligence, adaptive technologies, embodied learning, and intelligent tutoring systems, from early childhood to higher education. Grounded in evidence-based practice, the volume bridges neuroscience and gaming to provide valuable insights for educators, researchers, policymakers, and developers shaping the future of mathematics learning through technology-driven innovation and impact.

  • Sarcoma Immunology and Immunotherapy

    From Cellular Mechanisms to Clinical Translation
    • 1st Edition
    • Joseph Crompton
    • English
    Sarcoma Immunology and Immunotherapy offers a timely and comprehensive review of the rapidly evolving field of sarcoma immunology and immunotherapy. This book serves as an essential resource for healthcare professionals, scientists, and patients, providing insights into the immunologic features of sarcoma and the latest immune-based treatments. Focussing on the recent advances, the book discusses the sarcoma microenvironment and the development of innovative immunotherapies tailored for sarcoma patients. Readers will benefit from a thorough overview of existing knowledge, encompassing foundational concepts in sarcoma immunology, a detailed examination of laboratory research, and a complete summary of ongoing immunotherapy trials. This holistic approach ensures a robust understanding of the current landscape in sarcoma research and treatment. By equipping readers with essential background information and comprehensive reviews, this book fosters a deeper understanding of sarcoma immunology and therapeutic strategies. It empowers healthcare professionals and scientists to stay abreast of critical studies, ultimately enhancing patient care and outcomes in this challenging field.

  • Euphorbiaceae Family Oriented Drug Discovery

    Exploration of Isolation, Identification, Total Synthesis, and Drug Discovery Based on Natural Products from Euphorbiaceae Family
    • 1st Edition
    • Bingjie Li + 1 more
    • English
    Euphorbiaceae Family Oriented Drug Discovery, Exploration of Isolation, Identification, Total Synthesis, and Drug Discovery Based on Natural Products from Euphorbiaceae Family, a volume in the Drug Discovery Opinions series, aims to comprehensively explore the isolation, identification, synthesis, and drug discovery based on natural products derived from the Euphorbiaceae family. Focused on the isolation, identification, synthesis of bioactive compounds, and drug discovery techniques, the contents of the book are organized into ten chapters. The book opens with an introduction to the Euphorbiaceae family, its botanical overview, medicinal significance, and the importance of exploring its natural products for drug discovery.The next chapters focus on specific techniques for identification and synthesis of natural products, cover the antitumor activities and mechanisms of action of natural products, and discuss the specific antimicrobial properties and mechanisms of action. Final sections discuss anti-inflammatory properties, pharmacology, drug discovery processes for Euphorbiaceae Natural Products, and describe challenges and future directions in research. The final chapter presents final considerations, summarizing key findings and insights from the book.

  • Enzymology for Biotechnologists

    • 1st Edition
    • Timir Tripathi + 1 more
    • English
    Enzymology for Biotechnologists provides a comprehensive introduction to enzymology with a strong focus on its applications in biotechnology. Chapters cover the fundamental principles of enzyme structure, function, kinetics, and assays, and extends into advanced topics such as enzyme production, immobilization, reactor design, process intensification, and the use of enzymes in low-water and green solvent systems. Special attention is given to industrial applications, grey and white biotechnology, and the integration of processes that highlight sustainability and innovation. The book presents enzymology from a perspective of biotechnology, and focuses on scale-up, process design, and industrial applications. This targeted approach makes sure that BTech, MTech, MSc, and PhD students, as well as researchers and professionals, gain not only a solid understanding of enzyme science but also its translation into real-world biotechnological processes.

  • RNA-Binding Proteins Part D

    • 1st Edition
    • Volume 746
    • English
    A central theme of this volume is the dynamic relationship between RNA structure, RNA-binding proteins, and cellular organization. The chapters integrate experimental, computational, biochemical, biophysical, imaging, and systems-level approaches to investigate how RNA–protein interactions regulate RNA processing, translation, localization, stability, phase separation, and cellular stress responses. As Volume 746 of the Methods in Enzymology series, the volume emphasizes the integration of methodological innovation with biological applications, providing researchers with practical approaches to dissect how RNA–protein interactions govern RNA fate and function, biomolecular condensate formation, and stress granule assembly.Overall, this collection highlights the transition of RNA biology from a primarily sequence-centered discipline toward a more dynamic view in which RNA structure, molecular interactions, phase separation, cellular organization, and signaling are intimately connected. It will therefore be a valuable resource for researchers and students seeking both practical methodologies and mechanistic insights into the rapidly expanding field of RNA biology.

  • Neonatal Surgery

    Techniques, Evidence and Outcomes
    • 1st Edition
    • David J. Hackam
    • English
    Neonatal Surgery: Techniques, Evidence, and Outcomes addresses the growing need for specialized surgical care in neonates, whose unique physiology demands distinct considerations from other surgical populations. Written by leaders in the field, this definitive textbook is the first devoted entirely to neonatal surgery, filling a vital gap in the literature with evidence-based guidance on timing, technique, and postoperative management for optimal outcomes. The book opens with the general care of the neonatal surgical patient, covering anatomy and physiology, preoperative workup, anesthesia, pain management, nursing, family experience, transport, nutrition, pharmacy, vascular access, and radiographic considerations. Subsequent sections address specialized areas including head and neck, thoracic, abdominal, urologic, orthopedic, neurosurgical, plastic and reconstructive, and congenital heart surgery, each offering detailed, evidence-based guidelines and techniques for managing specific conditions. The book concludes with a look at the future of neonatal surgery and considerations for surgery in low- and middle-income countries. An invaluable resource for clinical learners and practicing surgeons alike, it serves as a critical how-to guide for students and residents and an authoritative reference for practicing surgeons, including evidence-based management strategies. Researchers will find it indispensable for understanding the metabolic and physiological responses to neonatal surgery, adding translational relevance to their work. This textbook is essential for anyone involved in the surgical care of neonates, providing the knowledge needed to achieve the best possible outcomes

  • Sleep Neurology

    • 1st Edition
    • Anne Marie Morse
    • English
    Sleep Neurology explores the intricate relationship between sleep and neurological health, bridging the gap between theoretical knowledge and practical application. This comprehensive reference highlights the role of sleep in overall health and provides an examination of how sleep influences a wide range of neurological disorders. From neurodevelopmental issues to neurodegenerative diseases, this book offers a detailed review of how sleep science can be applied to improve patient outcomes in various neurological conditions. Structured around key neurological topics, the book offers insights into conditions such as epilepsy, stroke, and traumatic brain injury, emphasizing the importance of sleep management in their treatment. Each chapter not only discusses the scientific underpinnings of sleep but also provides tangible strategies for integrating sleep health into primary neurological care.

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