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Academic Press

    • Cryo-EM Methods and Management

      • 1st Edition
      • Edward T. Eng + 2 more
      • English
      Cryo-EM Methods and Management provides a detailed introduction to the latest advances of cryo-EM, from technical innovations to the logistical challenges of maintaining a modern cryo-EM facility. The book consists of four parts, beginning with an overview of cryo-EM. It then moves on to discuss Cryo-EM workflows, with chapters focusing on sample handling and preparation, data collection and hardware, and data procession and visualization. The third part centers on aspects of cryo-EM infrastructure and community building, considering facility set-up and management, monitoring facility performance, instrumentation monitoring , data sharing and standards, and training and development standards. The book then closes with a section looking towards future prospects for cryo-EM. This is an ideal reference for cryo-EM facility and lab managers, providing guidance to the often-overlooked aspect of facility building and management. Additionally researchers working with cryo-EM across molecular biology, structural biology, cell biology and biochemistry will benefit from this book.

    • Pediatric Substance Exposure

      • 1st Edition
      • Ju Lee Oei
      • English
      Pediatric Substance Exposure is a crucial resource for medical practitioners focusing on the long-term management of children exposed to addictive substances during pregnancy. It provides guidance on supporting families affected by substance abuse, starting with a comprehensive overview of epidemiology and global policy. The book examines various substances and their impact on children, discussing fetal management, infant and child care, and addressing family needs as the child grows. Beyond the basics, the book reviews social aspects, future research, and policy needs. Clinicians and researchers will find it invaluable for evidence-based decision-making and optimal treatment strategies.

    • Quick Guide to Diabetes Mellitus

      • 2nd Edition
      • William Winter E + 3 more
      • English
      Quick Guide to Diabetes Mellitus, Second Edition provides essential knowledge on the pathophysiology, etiology, epidemiology, diagnosis, laboratory evaluation, and basic clinical management of diabetes and its complications targeted to laboratory scientists and technicians. Eleven percent of the U.S. population have been diagnosed with diabetes mellitus, and laboratory scientists play an essential role in the diagnosis, monitoring, and management of this disease. This reference presents an easy-to-read question-and-answer format that will provide fundamental knowledge and aid in commonly encountered clinical challenges.This updated release includes new information on genetic and environmental risk factors for type 1 and 2 diabetes, pediatric glucose targets per American Diabetes Association Standards, type 2 diabetes management sections, including treatment guidelines and information on glucagon-like peptide-1 receptor agonists and gastric bypass surgery.

    • Nutritional Strategies, Predictive Models, and Sustainable Policies

      • 1st Edition
      • Sandeep K. Panda + 2 more
      • English
      Nutritional Strategies, Predictive Models, and Sustainable Policies brings together scientists, professors, and policymakers from over 10 countries to cover strategies and approaches to improve human health by focusing on the nutritional needs of children, pregnant women, and patients from around the world. Sections cover existing policies in specific geographical areas, critical reviews on the scientific updates of maternal, pediatric, and geriatric nutrition and how the Pandemic disrupted nutritional strategies, review predictive models on different nutrition categories for certain diseases and cancers, and highlight international and regional policies related to nutrition in war affected countries.

    • Mangrove Ecosystem Dynamics

      • 1st Edition
      • Daniel M Alongi
      • English
      Mangrove Ecosystem Dynamics presents a comprehensive account of the various functions of mangrove habitats, from spatial dynamics of intertidal ecosystems to nutrient and biogeochemical cycling in sediments, tidal and coastal waters, and dependent species. This process-oriented approach is necessary to further understand the role of these dynamic habitats in the coastal ocean, and as a next step towards developing adequate strategies for mangrove conservation, management, and sustainable use.Written by a leading expert in mangrove biology and tropical marine ecology, this book takes an energetics approach to summarize the latest developments and knowledge in the field of mangrove ecology. Initial chapters discuss the fundamentals of intertidal environments and the spatial and temporal dynamics of mangrove habitats. Latter chapters address recent advances in food web energetics in tidal waters, exploring benthic invertebrate, planktonic, fish, and arboreal food webs. Final sections detail decomposition of organic matter, nutrient cycling, and carbon sequestration.Mangro... Ecosystem Dynamics addresses rapidly emerging and vital issues of climate change, blue carbon, sustainable management and restoration, and the connectivity and interdependence between mangroves and other coastal habitats and species. This new work offers a comprehensive functional view of the current and future state of mangrove ecosystems that will greatly benefit coastal and marine biologists, resource managers, conservationists, and students alike.

    • Phytochemicals and Hallmarks of Cancer

      From Molecules to Medicine
      • 1st Edition
      • Gautam Sethi + 1 more
      • English
      Phytochemicals and Hallmarks of Cancer: From Molecules to Medicine delves into the potential of phytomedicine to effectively address both established and emerging hallmarks of cancer, offering valuable insights into their translational applications from bench to bedside. The book provides comprehensive information about how the plant-derived product tackles cancer by targeting different hall markers that drive cancer progression. In 12 chapters the book not only describes the implications of plant products on cancer immunotherapy, gives insight in the hurdles in clinical translating plant derived products for cancer therapy, but also focuses on the therapeutic aspects of phytochemicals, providing insights into how understanding of mechanism of actions of phytochemicals can aid to develop innovative therapies.By addressing these knowledge and information needs Phytochemicals and Hallmarks of Cancer: From Molecules to Medicine is designed to be accessible to clinicians and researchers alike in the field of phytochemical applications in medicine.

    • Advances in Hepatorenal Syndrome Research

      Untangling Pathophysiology, Improving Diagnostic Strategies, and Leveraging Therapeutic Innovations
      • 1st Edition
      • Justin Belcher
      • English
      Advances in Hepatorenal Syndrome Research: Untangling Pathophysiology, Improving Diagnostic Strategies, and Therapeutic Innovations is a comprehensive review of the historical perspectives, prevalence, and prognosis of HRS, offering insights into its evolving clinical recognition and shifting paradigms of pathophysiology. Explore the multifaceted pathophysiology of HRS as experts navigate the complexities of cardiac dysfunction, inflammatory cytokines, and other modern understandings shaping the field. Explore differential diagnosis, uncovering alternative etiologies and current diagnostic criteria, while shedding light on biomarkers and novel diagnostic tests revolutionizing patient assessment. Contents will also guide readers through the utility of point-of-care ultrasound in intravascular volume assessment sets the stage for exploring medical therapy options, including vasoconstrictors and albumin usage. Written by a team of experts, this comprehensive reference highlights the intricate pathophysiology of hepatorenal syndrome while delivering the most up-to-date insights into diagnostic and therapeutic approaches. Historically overshadowed by grim prognoses, hepatorenal syndrome has undergone a renaissance of interest due to recent breakthroughs, revolutionizing treatment paradigms. Whether you're a seasoned practitioner or a burgeoning researcher immersing yourself in this dynamic field, this resource offers a thorough examination, encompassing novel diagnostic criteria, innovative biomarkers, and state-of-the-art treatments.

    • Computational Approaches to Natural Products Discovery

      • 1st Edition
      • Volume 730
      • English
      Computational Approaches to Natural Products Discovery, Volume 720 provides descriptions of the latest techniques in computational methods for the study of natural products. Techniques covered are related to genome mining, natural product biosynthesis, natural product evolution, and natural product structure. Chapters in this new release cover Prediction of natural product bioactivity from BGC sequence to guide genome mining efforts, Genome mining for resistance genes to identify bioactive natural products with ARTS, Predicting lasso peptide structure with LassoPred, Predicting lanthipeptide structure with Rosetta, Using lsaBGC to investigate BGC Evolution, and an Analysis of BGC evolution with CORASON.

    • Marine Operations for Offshore Wind Turbines

      Volume 1: Fundamentals and Applications
      • 1st Edition
      • Zhiyu Jiang + 1 more
      • English
      Published as an Open Access book freely available for download on Science Direct, Marine Operations for Offshore Wind Turbines, Volume 1: Fundamentals and Application is a practical reference that links fundamentals to methods to application in this unique, important, and highly interdisciplinary area, helping readers to ensure operational safety, reduced installation costs, and improved wind farm efficiency and reliability. The first part of the book introduces the fundamentals of offshore wind energy systems and marine operations, along with analysis methods and numerical modelling and simulation tools. The second section focuses on in-depth case studies based on the authors’ own research and incorporating real-world practical experience in key areas, guiding the reader through lifting operations for turbine components, environmental loads, motion control, structural modelling, and safety assessment for installations, modelling, analysis and control of full assembly installation, and design and optimization for floating installations. Finally, the critical phases of transportation and final mooring hook-up are introduced, and a concluding chapter provides an overview of recent trends and emerging topics, such as robotic technologies, artificial intelligence, and advanced decommissioning solutions, offering routes for future research and development. A volume in the Elsevier Wind Energy Engineering Series, this is an essential resource for all those looking learn the fundamentals, to improve their understanding, and to gain insights into installation concepts, analysis methods, modelling approaches, key tools, and problems and challenges, including researchers, students, engineers, R&D, policy makers and industry professionals.

    • Biosimilars and Biologics in Cancer Treatment

      An Era in Therapeutic Strategies
      • 1st Edition
      • Kuttiappan Anitha + 2 more
      • English
      Biosimilars and Biologics in Cancer Therapy: An Era in Therapeutic Strategies offers an in-depth exploration of the evolving role of biosimilars and biologics in cancer treatment. The book presents a clear overview of the challenges and opportunities these therapies bring, backed by current evidence and a thorough discussion of regulatory and economic factors. It serves as a comprehensive educational resource designed to bridge the gap between cutting-edge research and everyday clinical practice, providing readers with a solid foundation in the fundamental principles, historical context, and mechanisms of action behind biologics and biosimilars.Readers will also discover emerging strategies such as combination therapies and personalized medicine, ensuring the content is relevant for researchers, clinicians, and other healthcare professionals. International expert contributors share the latest advancements, offering practical guidance for integrating biosimilars and biologics into cancer care and inspiring future oncology research.

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