Phytochemicals and Hallmarks of Cancer
From Molecules to Medicine
- 1st Edition - January 1, 2026
- Imprint: Academic Press
- Editors: Gautam Sethi, Lekshmi R. Nath
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 3 4 0 8 4 - 0
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 4 0 8 5 - 7
Phytochemicals and Hallmarks of Cancer: From Molecules to Medicine delves into the potential of phytomedicine to effectively address both established and emerging hallmarks of can… Read more
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Phytochemicals and Hallmarks of Cancer: From Molecules to Medicine delves into the potential of phytomedicine to effectively address both established and emerging hallmarks of cancer, offering valuable insights into their translational applications from bench to bedside. The book provides comprehensive information about how the plant-derived product tackles cancer by targeting different hall markers that drive cancer progression. In 12 chapters the book not only describes the implications of plant products on cancer immunotherapy, gives insight in the hurdles in clinical translating plant derived products for cancer therapy, but also focuses on the therapeutic aspects of phytochemicals, providing insights into how understanding of mechanism of actions of phytochemicals can aid to develop innovative therapies. By addressing these knowledge and information needs Phytochemicals and Hallmarks of Cancer: From Molecules to Medicine is designed to be accessible to clinicians and researchers alike in the field of phytochemical applications in medicine.
- Provides a detailed overview of the molecular mechanisms through which phytochemicals can modulate various hallmarks of cancer
- Discusses the potential of phytochemicals to reverse the metastatic process via inhibition of migration, invasion, and angiogenesis
- Covers the implication of natural products as apoptosis inducers
(post) graduate students as well as early- to mid-stage researchers in field of oncology and disease therapy especially cancer, also working on drug discovery and scientists in field of drug delivery
1. Phytochemical-mediated targeting of apoptotic pathways in cancer cells
2. Targeting autophagy with phytochemicals
3. Impact of phytochemicals on cancer cell migration, invasion and angiogenesis
4. Phytochemicals as cell cycle modulators
5. Phytochemicals to suppress tumor-promoting inflammation
6. Impact of phytochemicals on cancer-associated Extracellular matrix(ECM)
7. Implication of phytochemicals for cancer immunotherapy
8. Phytochemical mediated re-programming of energy metabolism in cancer
9. Phytoradiotherapy: An Integrative Approach to Cancer Treatment
10. Cancer epigenetic modulation mediated by phytochemicals
11. Natural products as anti-cancer drugs: where do we stand now?
12. Hurdles in clinical translation plant-derived natural products for cancer therapy
2. Targeting autophagy with phytochemicals
3. Impact of phytochemicals on cancer cell migration, invasion and angiogenesis
4. Phytochemicals as cell cycle modulators
5. Phytochemicals to suppress tumor-promoting inflammation
6. Impact of phytochemicals on cancer-associated Extracellular matrix(ECM)
7. Implication of phytochemicals for cancer immunotherapy
8. Phytochemical mediated re-programming of energy metabolism in cancer
9. Phytoradiotherapy: An Integrative Approach to Cancer Treatment
10. Cancer epigenetic modulation mediated by phytochemicals
11. Natural products as anti-cancer drugs: where do we stand now?
12. Hurdles in clinical translation plant-derived natural products for cancer therapy
- Edition: 1
- Published: January 1, 2026
- Imprint: Academic Press
- Language: English
GS
Gautam Sethi
Dr. Gautam Sethi is a tenured Associate Professor in Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore. The focus of his research over the past few years has been to elucidate the mechanism(s) of activation of oncogenic transcription factors by carcinogens and inflammatory agents and the identification of novel inhibitors of these proteins for prevention of and therapy for cancer. The findings of his research work have so far resulted several publications in high impact factor peer reviewed journals and many international awards. He also serves as an editorial board member for over more than 15 international journals
Affiliations and expertise
Associate Professor, Yong Loo Lin School of Medicine, National University of Singapore, SingaporeLN
Lekshmi R. Nath
Dr Lekshmi R. Nath is working as an Associate Professor in the Department of Pharmacognosy at Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, India. She pursued her PhD. in Cancer Research Program. She has more than 50 publications and has been invited as a resource person to many national and international conferences. She is the editorial board member and reviewer of high-impact scientific journals. Her current research interest includes the study of signalling events associated with the fatty liver to Hepatocellular carcinoma, elucidating the role of plant-derived pure compounds in cancer chemoprevention, chemo sensitization, and chemotherapy. She is also exploring the potential of traditional knowledge for cancer and various infectious diseases, their mechanism of action and validation through pre-clinical models
Affiliations and expertise
Amrita School of Pharmacy, India