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Academic Press

    • Nutrigenomics for Clinical Medicine and Personalized Healthcare

      • 1st Edition
      • Dhavendra Kumar + 1 more
      • English
      Nutrigenomics for Clinical Medicine and Personalized Healthcare presents an overview of the challenges associated with bringing personalized nutrition to mainstream dietary practices in healthcare. Broken into 18 chapters, the book addresses everything from the fundamental principles of nutrigenetics and nutrigenomics to the role of nutritional factors in various diseases and disorders and the ethical practices surrounding nutritional genomics. Compiled for nutrition researchers, nutritionists, health professionals, and graduate students studying related topics, this is sure to be a welcomed reference.

    • Lifestyle Epigenomics

      • 1st Edition
      • Ana B Crujeiras
      • English
      Lifestyle Epigenomics, a new volume in the Translational Epigenetics series, comprehensively details the interplay between lifestyle factors and epigenetic modifications associated with the onset of noncommunicable diseases and aging, shedding light on potential preventive and therapeutic strategies for disease from an epigenomics perspective. Here, more than 35 international experts in the field consider how lifestyle choices or habits can condition or prevent disease, along with tools for new research, from bioinformatics methodology to non-invasive sampling.Early, foundational chapters are followed by all-inclusive sections on epigenetic machinery in health and disease; dietary factors and epigenetics; adiposity and physical activity and epigenetics; psychological stress, social environment, toxins and contaminants exposure effects on epigenetics; and transgenerational and childhood epigenetics. To support understanding, each chapter includes a summary and key points lists, terms and definition, as well as research case studies outlining core components of recent studies, detailing their conditions, research techniques involved, and outcomes.

    • The Honey Bee and Climate Change

      • 1st Edition
      • Gloria DeGrandi-Hoffman
      • English
      A honey bee colony is a community of interacting organisms continually adjusting their behaviors, both individually and collectively, in response to even the subtlest changes in the environment. It’s only logical then, that the more significant changes and stressors due to climate change will push the colony to its limits, disrupting the delicate balance of the hive and threatening the survival of the colony. Honey Bees and Climate Change is the first and only book to examine the responses of honey bees to climate change and the threat it poses to their ability to thrive and survive. Drawing on systems science and the central theme that all outcomes are products of an interconnected system, the book will address how climate change is affecting honey bee nutrition, growth, and overwinter survival, which in turn threaten commercial beekeeping and crop production. Impacts on other pollinators will be touched on as well. Finally, potential mitigating strategies, key areas of action, and the future outlook will be covered.Written by a leading scientist with over 40 years of experience studying honey bee physiology, nutrition, colony survival, and the impact of climate change on the colony, Honey Bees and Climate Change is crucial reading for students and researchers studying honey bees, especially those with an interest in the impacts of climate change on pollinators. The inclusion of key terms and definitions as well as case studies make this work an excellent supplementary text for courses on honey bee biology, apiculture, pollinator conservation, or climate change ecology.

    • Cadmium Contamination in Soils and Plants

      Mechanisms and Mitigation
      • 1st Edition
      • Fang-Jie Zhao + 2 more
      • English
      Cadmium Contamination in Soils and Plants: Mechanisms and Mitigation focuses on the processes and mechanisms of transformation and transport of cadmium (Cd) in soil-plant systems, covering aspects from inputs and outputs of Cd to/from soil-plant systems, biogeochemical transformation of Cd in soil, uptake and transport of Cd in plants, toxicity and detoxification of Cd in microorganisms and plants, dietary intake of Cd and impact on human health, risk assessment and bioremediation technologies to mitigate Cd contamination. Contamination of soil with Cd, a highly toxic heavy metal, is a global problem due to both geogenic reasons and anthropogenic activities. Cd is readily taken up by plants, causing toxicities to plants and posing a significant risk to human health via dietary exposure. There has been much scientific progress in understanding various aspects of the topic, especially the mechanisms and mitigation technologies. This book to synthesizes and presents a comprehensive look at the state-of-the-art knowledge of Cd in soil-plant systems. Cadmium Contamination in Soils and Plants serves as a key authoritative resource for researchers, graduate students, environmental protection professionals and policy makers who are interested in the issues of soil contamination, agricultural sustainability, food safety and public health, and environmental protection and remediation.

    • Step-by-step Approach to the Radiological Evaluation of Arthritis

      • 1st Edition
      • Muthusamy Chandramohan + 1 more
      • English
      Step-by-step Approach in the Radiological Evaluation of Arthritis is a concise, practical reference source for the evaluation and interpretation of arthritis images. The book begins by briefly reviewing relevant anatomy, clinical and biochemical considerations. Subsequent chapters analyze specific arthritis indications in radiographic images using a simple, systematic approach. The book presents guidelines for when and when not to consider other advanced imaging techniques. Final chapters are devoted to troubleshooting strategies and key not-to-miss indications in rheumatic imaging. X-rays play a crucial role in the diagnosis and management of arthritis. This book’s clear and simple explanations of the subtleties and distinctions in arthritis imaging aims to improve investigative accuracy and aid healthcare professionals in monitoring disease progression and driving treatment decisions. Clinicians and radiologists in rheumatology as well as orthopedics will find certain value in integrating this must-have handbook into their daily practice.

    • Fetal Metabolic Programming in Obesity and Diabetes

      From Mechanisms to Preventive Therapy
      • 1st Edition
      • Luis Sobrevia
      • English
      Fetal Metabolic Programming in Obesity and Diabetes: From Mechanisms to Preventive Therapy describes the consequences of cellular and molecular aspects of maternal obesity (before and during pregnancy), diabetes mellitus (pregestational and gestational), and gestational diabesity (i.e., women with pre-pregnancy obesity that developed GDM). The book covers the clinical aspects of mothers and children and the protocols for treating these diseases during pregnancy. Since the patients' clinical information correlates with metabolic parameters at a cellular and systemic level, it covers several pieces of evidence, addressing the pathophysiology of obesity and diabetes in pregnancy.This is an important resource for health professionals, researchers, and postdocs in obesity diabetes, as well as public health, physiology, biochemistry, cell biology, cell physiology, cell metabolism, and clinical medicine.

    • The Rat Nervous System

      • 5th Edition
      • George Paxinos + 1 more
      • English
      The Rat Nervous System, Fifth Edition is an indispensable guide for researchers and students in neuroscience who are working on the rat and mouse as experimental models. The new edition provides thorough updates throughout, including the latest information in an active field of research on the brain, spinal cord, and peripheral nervous system and their unique functions. Readers will learn how to formulate sound hypotheses as well as carry out accurate research models.

    • The Renaissance in GPCR Research and Drug Discovery

      Receptor Function, Receptor Structure, New Techniques, Characterization of Drug Activity, Drug Discovery
      • 1st Edition
      • Terry P. Kenakin
      • English
      The Renaissance in GPCR Research and Drug Discovery: Receptor Function, Receptor Structure, New Techniques, Characterization of Drug Activity, Drug Discovery is a comprehensive reference for pharmacology researchers. It focuses on utilizing novel aspects of GPCR function for therapeutic advantage and applying new chemical types to modify GPCR behavior. Recent advancements have revitalized GPCR discovery, opening unexplored avenues for new drug development. The book's content is meticulously divided into five distinct parts, covering evolutionary perspectives, novel functions, investigative technologies, therapeutic modalities, and a broad range of GPCR ligands.Beyond these key topics, the book delves into the evolution of GPCRs as drug targets, the mechanisms behind their novel functions, and the latest technologies driving research and discovery. It also highlights new and recently approved therapeutic modalities and provides a broad coverage of GPCR ligands. Edited and authored by leading researchers, this book serves as an essential reference for drug discovery researchers and medicinal chemists, as well as AI researchers exploring this drug discovery space.

    • Obesity

      Integrating Physiological, Pathophysiological and Clinical Perspectives
      • 1st Edition
      • Javier Gonzalez
      • English
      Obesity: Integrating Physiological, Pathophysiological and Clinical Perspectives, a volume in Elsevier's Hot Topics in Physiology series, provides coverage across a wide range of physiological disciplines, covering obesity science at a sufficient level to be understood by physiologists who may not be an expert in all subdisciplines, and with an aim of unifying physiological perspectives on obesity. Divided into three sections, the book covers causes of obesity (e.g., regulation of energy balance), the consequences of obesity (e.g., metabolic, disease risk etc.), and strategies to prevent and/or manage obesity (e.g., bariatric surgery, pharmacotherapy, and lifestyle).This volume is published in association with the International Union of Physiological Sciences (IUPS). It will be of great interest for clinicians, dieticians, exercise physiologists, and molecular biologists.

    • Nerve Growth Factor

      From Neuron Development to Neurology
      • 1st Edition
      • Antonino Cattaneo + 1 more
      • English
      Nerve growth factor: From Neuron Development to Neurology, the latest release in the Molecular Mediators in Health and Disease series, offers a complete guide to nerve growth factor (NGF) across health and disease. Sections cover key properties, the latest advances, and biomedical applications of this neuropeptide. The book begins with an introduction and historical overview of the discovery of NGF before exploring its molecular characteristics. It then covers NGF in organ function, with chapters discussing the brain, immune system, blood vessels, heart, reproductive organs, teeth, and lungs. NGF pharmacology is then considered, with a focus on NGF as a therapeutic agent.The final section of the book covers NGF across diseases, including Alzheimer’s disease, cancer, diseases of the eye, chronic pain, and visceral disfunctions. Throughout the book, NGF is considered in the context of both mammalian and non-mammalian biology, making it an ideal reference for researchers working across the fields of cell biology, molecular biology, pharmacology, and other biomedical areas.

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