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Elsevier

Academic Press

  • Transesophageal Echocardiography

    Basic and Advanced Aspects and Clinical Field of Application
    • 1st Edition
    • Antonello D’Andrea
    • English
    Transesophageal Echocardiography: Basic and Advanced Aspects and Clinical Field of Application provides clinicians and echocardiography professionals with a thorough and practical resource covering both the fundamental principles and advanced clinical uses of TEE. It benefits the audience by delivering step-by-step guidance on image acquisition, interpretation of valve and ventricular pathology, and real-world applications in perioperative, emergency, and interventional settings. Richly illustrated and supplemented by instructional videos, the book’s contents include diagnostic techniques, perioperative management, assessment of prosthetic and congenital heart conditions, and specialized topics such as TEE in sports cardiology and critical care—empowering readers to improve patient outcomes and master the latest advancements in cardiovascular imaging.

  • Quercetin in Drug Discovery

    • 1st Edition
    • Gautam Sethi + 2 more
    • English
    Quercetin in Drug Discovery is a detailed reference exploring the multifaceted pharmacological potential of quercetin, a naturally occurring flavonoid with significant therapeutic promise. Addressing the critical need for consolidated knowledge, this guide highlights quercetin’s diverse biological activities and the translational challenges limiting its clinical applications, making it essential for researchers and pharmaceutical scientists. The comprehensive table of contents covers quercetin’s pharmacological properties, molecular docking studies, and ADME profiles, alongside therapeutic applications in cardiovascular diseases, cancer, and other conditions. It further examines bioavailability enhancement strategies, drug formulation, innovative delivery systems, and clinical trial evidence. Contributions from leading experts provide detailed insights into signaling pathways, molecular targets, and synthetic derivatives. Quercetin in Drug Discovery equips pharmacologists, medicinal chemists, and pharmaceutical scientists with critical information to advance research and drug development. By addressing bioavailability issues and regulatory considerations, this reference supports the translation of quercetin from bench to bedside, fostering innovation in natural product-based therapeutics.

  • Chronic Kidney Disease Management Through Herbal Phytoceuticals

    Mechanistic Findings and Phyto-Based Therapy for Chronic Kidney Disease Management
    • 1st Edition
    • Kalicharan Sharma
    • English
    Chronic Kidney Disease Management Through Herbal Phytoceuticals: Mechanistic Findings and Phyto-Based Therapy for Chronic Kidney Disease Management examines chronic kidney disease (CKD) through the lens of plant-, marine-, and microbe-derived compounds. The field increasingly requires safer, non-invasive therapies that complement existing regimens while clarifying mechanisms of action. By combining ethnobotanical knowledge with contemporary computational methods, this work serves as a translational resource for researchers, clinicians, and students seeking evidence-based, mechanism-driven phytopharmaceutical approaches to nephroprotection and disease modification. Readers gain a framework for integrating traditional knowledge with modern drug discovery pipelines. The table of contents outlines a progression from foundational concepts to translational applications. Chapters 1–3 cover the global burden, pathophysiology, and current management of CKD. Chapter 4 identifies druggable molecular targets. Chapters 5–7 survey plant-based phytoceuticals for CKD management, marine natural products as emerging CKD therapies, and microbial-derived candidates as potential CKD agents, supported by efficacy and safety data. Chapters 8–9 apply molecular docking and docking-based mechanistic insights to plant, marine, and microbial compounds. Chapters 10–12 address clinically validated phytopharmaceuticals... formulation science, and global regulatory considerations. Chapter 13 presents clinical and preclinical case studies to illustrate practical applications. This book delivers clear benefits to end users by providing integrated, mechanism-driven insights that connect basic science to clinical decision-making. Readers gain access to curated data on plant-, marine-, and microbial-derived compounds along with their targets, efficacy, and safety, supported by docking-based mechanistic validation. It also addresses formulation challenges, regulatory pathways, and quality-control considerations essential for translating phytopharmaceuticals from bench to bedside, including safety assessment and scalable product development. This blend of theory and practical guidance supports researchers designing studies, clinicians implementing evidence-based phytotherapy, and educators teaching multidisciplinary approaches to CKD management across academic and clinical settings.

  • Physiology, Medicine, and Health Sciences

    Catalyzed by Biomedical Engineering Modeling
    • 1st Edition
    • Dhanjoo N. Ghista + 1 more
    • English
    Physiology, Medicine, and Health Sciences: Catalyzed by Biomedical Engineering Modeling is a quantitative handbook for mathematical and quantitative analysis of anatomical structures, physiological and organ systems, medical tests and surgical procedures. This book’s purpose is to demonstrate how fundamental mathematical modeling can be incorporated into physiology, medicine, and health sciences research, application, and clinical practice to make these disciplines more quantitative and computational, and hence more explanatory and informative. The book also provides quantitative formulation of medical procedures, towards supporting the growing field of precision medicine. Each chapter includes a robust introduction to the BME and mathematical concepts necessary to understand their application to the indicated medical and biological systems, beginning with Intrinsic Anatomy, showing how anatomical structures are intrinsically optimally designed for their functional performance, such as the intrinsic hyperboloid shape of the spinal vertebral body (as a lightweight, high-strength structure), and the ellipsoidal shape of the left ventricle that enables it to contract efficiently. Other BME and modelling concepts covered include: Physiological Engineering, in quantifying physiological systems and developing indices for assessing their function and dysfunction leading to medical diagnostics; Precision Medicine, by developing biomedical engineering formulation of medical diagnostic and assessment methods and indices, including the new concept of non-dimensional indices in medical assessment, such as cardiac contractility index for risk of heart failure and diabetes index for accurate diagnosis of diabetes; and, Computational Surgery, involving surgical design of prosthetic devices based on the intrinsic design of the fractured structure, such as the design of the spinal vertebral body cage for fractured vertebral body to preserve its intrinsic hyperboloid shape. Each chapter provides in-depth guidance on the engineering and mathematical concepts, methodology, and procedures for applying the formulas and equations to the appropriate biomedical and physiological systems, as well as step-by-step procedures for creating models for a wealth of specific applications.

  • Cell Death Part G

    • 1st Edition
    • Volume 214
    • English

  • Advances in Virus Research

    • 1st Edition
    • Volume 127
    • English

  • Translational Insights in Regenerative Medicine

    • 1st Edition
    • Volume 228
    • English
    Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advances in Animal Genomics

    • 2nd Edition
    • Sukanta Mondal + 1 more
    • English
    Advances in Animal Genomics, 2nd Edition offers a comprehensive exploration of the latest developments in animal genomics and biotechnology. This updated edition integrates traditional and cutting-edge omics approaches—including genomics, transcriptomics, epigenomics, and genome editing technologies—to advance sustainable livestock production and genetic improvement. Covering a wide range of topics from reproductive technologies, cloning, and stem cell applications to CRISPR/Cas9 genome editing, molecular markers, and nanobiotechnology, this volume delves into the molecular mechanisms underlying key traits such as yield, disease resistance, and stress tolerance. It also addresses emerging areas like microbial metagenomics, bioinformatics, gene therapy, and policy frameworks, providing readers with a holistic understanding of the scientific tools and ethical considerations shaping the future of animal biotechnology. Designed for scientists, researchers, students, educators, and professionals across agriculture, veterinary science, and biotechnology, Advances in Animal Genomics, 2nd Edition serves as an essential resource for those seeking to harness genomics for improving animal health, productivity, and sustainability. For those engaged in academic research, applied breeding programs, or policy development, this book offers the knowledge and insights needed to meet the global challenges of food security and environmental stewardship through innovative genomic solutions.

  • RNA-binding proteins Part B

    • 1st Edition
    • Volume 744
    • English

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 123
    • English
    This book provides the latest advances in the role of artificial intelligence in the precision nutrition and development of personalized foods, precision nutrition in autoimmune diseases, the need for vitamin D fortification in tropical regions, the health benefits of bioactive peptides, the factors affecting digestibility and glycemic index of rice, bio-based materials for intelligent sensing of food quality and safety, solid-state fermentation of cereal grains for modulating phenolic compounds, natural additives stabilized with nanoclays and the concomitant mycotoxin contamination in foods, especially on climate-related challenges for food safety.

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