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Academic Press

  • The Matrix Metalloproteinases

    • 1st Edition
    • Volume 60
    • English
    The Matrix Metalloproteinases, Volume 60 in The Enzymes series, explores recent advances in the study of matrix metalloproteinases (MMPs), a critical family of enzymes involved in extracellular matrix remodeling and numerous physiological and pathological processes. This volume presents a comprehensive collection of chapters covering key aspects of MMP biology, including their structure, function, regulation, and detection through activity-based probes.Chapters in this release examine classical and selective MMP inhibitors, including specific targeting strategies for MMP-13, as well as the role of endogenous tissue inhibitors of metalloproteinases. Additional contributions explore the involvement of MMPs in various biological and disease contexts, including oral diseases, neurodegenerative disorders, neutrophil biology, and cancer progression.The volume also addresses current challenges and opportunities in the design of MMP-targeted therapeutics, highlighting advances in drug development and pharmacological applications. Together, these chapters provide valuable insights into the biochemical, physiological, and clinical significance of MMPs, making this volume an essential reference for researchers in enzymology, biochemistry, molecular biology, and biomedical sciences.

  • The Vitamins

    Fundamental Aspects in Nutrition and Health
    • 7th Edition
    • Gerald F. Combs Jr. + 1 more
    • English
    The Vitamins: Fundamental Aspects in Nutrition and Health, Seventh Edition presents both overviews and in-depth discussions of the sources, chemistry, metabolism and functions of these essential nutrients in physiology and health. Originally written 35 years ago as an upper-level collegiate text, The Vitamins, through its several revised editions, has become the leading recognized comprehensive reference in the fields of nutrition and food science. The seventh edition supports advanced instruction by providing detailed metabolic insights and key research findings that have shaped our understanding of these essential nutrients in human and animal health.Building upon previous editions, readers will gain updated insights into recent clinical research on all vitamins, with particular focus on vitamins A, D, E, K, C, thiamin, folate, and B12. The book also covers the latest findings on nutritional deficiencies, ecological strategies for addressing them, and vitamin–drug interactions. A revised table of deficiency signs in humans and animals is included, along with updated perspectives on the gut microbiome’s role in vitamin synthesis and metabolism. Expanded coverage highlights vitamins as supplements and examines their stability in foods, including losses during processing and cooking. Each chapter concludes with case studies, a quiz, and recommended readings.

  • International Review of Neurobiology

    • 1st Edition
    • Volume 190
    • English
    International Review of Neurobiology, Volume 190 highlights new advances in the field, with this volume presenting an in-depth chapter on imaging the glymphatic system in Huntington’s disease. This contribution explores the benefits of multimodal imaging approaches and their clinical implications, offering insights into disease mechanisms and potential diagnostic strategies.This volume provides a focused and up-to-date perspective on neurobiological research, serving as a valuable resource for researchers and clinicians interested in neurodegenerative disorders and advanced imaging techniques.

  • Plant-Induced Systemic Resistance

    Mechanisms and Applications Against Biotic and Abiotic Stressors
    • 1st Edition
    • Sengottayan Senthil-Nathan + 2 more
    • English
    Plant-Induced Systemic Resistance: Mechanisms and Applications Against Biotic and Abiotic Stressors examines how intrinsic defense signaling and state-of-the-art biotechnologies can fortify crops while reducing reliance on chemical inputs. This rigorous treatment unpacks the biochemical circuitry of induced immunity, the networks coordinating defense, and the innovative molecular biology tools that empower durable protection under a variety of stress triggers. Against the backdrop of rising pest pressures, evolving resistance patterns, and environmental concerns, it presents a forward-looking framework for integrating host defenses within comprehensive crop protection initiatives.This volume traces a clear trajectory from foundational concepts to precision management solutions, delivering data-driven methodologies, decision support tools, and scalable practices for sustainable agriculture, enriched by real-world case studies that illustrate adoption across research, extension, and industry contexts. Governance, regulatory considerations, and societal implications are woven throughout to ensure responsible innovation.Bridging lab-derived knowledge with field-ready interventions, this essential resource opens avenues for interdisciplinary collaboration to bolster plant resilience against various biotic and abiotic stressors, expanding the toolkit for integrated crop protection.

  • Operative Strategies in Pelvic Exenteration Surgery

    • 1st Edition
    • Michael E Kelly + 1 more
    • English
    Operative Strategies in Pelvic Exenteration Surgery is a reference for the surgical management of Pelvic Exenteration Surgery. It covers all aspects of surgery from the colorectal, urological, gynecological, and orthopedic point of view. Coverage consolidates the research of world-leaders and includes the history of exenterative study, outlining the current state and indicating future developments. The book also discusses the current surgical operative strategies for the management of locally advanced and recurrent pelvic neoplasms with illustrations, intra-op photos, and supplementary video material.Created from the experiences of an international collaboration of surgeons, this reference is the perfect reference for surgical oncologists, colorectal, gynecology, urology, and vascular surgeons as well as any group involved in complex pelvic surgery including complex open, laparoscopic, and robotic surgery.

  • Semiconductors and Semimetals

    • 1st Edition
    • Volume 123
    • English
    Semiconductors and Semimetals series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Catalytic Methods in Flow Chemistry: Part B

    • 1st Edition
    • Volume 78
    • English
    Catalytic Methods in Flow Chemistry: Part B, Volume 78 in the Advances in Catalysis series, highlights recent breakthroughs in catalytic methods under continuous‐flow conditions. This new volume presents chapters written by an international board of authors and explores cutting-edge strategies for enabling sustainable, scalable chemical synthesis. Topics include technological innovations that enhance efficiency and selectivity in continuous flow systems, the integration of biocatalysts for greener processes, and the development of streamlined approaches for active pharmaceutical ingredient (API) synthesis. Together, these contributions provide researchers and industrial practitioners with a comprehensive overview of advances that are shaping the future of flow chemistry and catalysis.

  • Nanomaterials for Stem Cell Modulation

    Innovation and Clinical Applications
    • 1st Edition
    • Syed Mahmood + 3 more
    • English
    Nanomaterials for Stem Cell Modulation: Innovation and Clinical Applications provides a comprehensive exploration of how nanotechnology is transforming stem cell science and regenerative medicine. This authoritative volume examines the physicochemical properties of nanomaterials, their interactions with stem cells, and their capacity to direct stem cell behaviors such as proliferation, differentiation, and therapeutic delivery. By blending foundational principles with cutting-edge innovations, the book bridges the gap between basic laboratory discoveries and clinical translation. Written by experts in the field, the book addresses the critical need for an integrated resource that unifies current knowledge with emerging research and practical applications. While interest in nanotechnology and stem cells continues to grow, the literature remains fragmented. This book fills that gap by offering structured insights, case studies, and guidance on selecting nanomaterial systems tailored to specific therapeutic goals, while also navigating regulatory and translational challenges. Designed for researchers, graduate students, and professionals, the text serves as both a practical guide and an academic reference across disciplines including nanotechnology, stem cell biology, regenerative medicine, tissue engineering, biomedical engineering, and pharmaceutical sciences. It is equally valuable for industry scientists and clinical researchers seeking to develop advanced nanomaterial-based therapies. With its interdisciplinary approach, Nanomaterials for Stem Cell Modulation empowers readers to understand fundamental mechanisms, explore current innovations, and apply nanotechnology-drive... strategies to solve complex healthcare challenges, making it an essential resource for advancing the future of regenerative medicine.

  • Data-Driven Developments of Entropic Materials under Extreme Conditions

    • 1st Edition
    • Yong Zhang
    • English
    Data-Driven Developments of Entropic Materials Under Extreme Conditions is a unique resource that offers readers an up-to-date understanding of data-driven design and development of entropic materials, including their behavior in extreme states. Drawing on examples and current research, the book covers the use of advanced data science in the development of high-entropy alloys, the dynamic behavior of entropic materials, and the development of entropic materials for nuclear, cryogenic, and high temperature applications.

  • Baicalin

    Pharmacology, Clinical Applications, and Future Prospects
    • 1st Edition
    • Xiao Ma + 2 more
    • English
    Baicalin: Pharmacology, Clinical Applications, and Future Prospects consolidates foundational knowledge and recent advancements in baicalin research, addressing critical aspects such as efficacy, toxicity, and pharmacokinetics. The book is organized into three main parts, beginning with the Foundations of Baicalin Research, which explores the historical and traditional uses of Baicalin, extraction methods, and modern research advancements. The second part, Pharmacology of Baicalin, provides an in-depth analysis of its mechanisms of action, bioavailability, and pharmacokinetic parameters, while also presenting current applications in various diseases, including pulmonary, liver, cardiovascular, and nervous system disorders. Finally, the Prospects section addresses future directions in drug delivery and administration.By balancing scientific rigor with accessibility, this book is tailored for PhD students, postdoctoral researchers, and pharmaceutical professionals. It highlights cutting-edge research and practical applications, empowering readers to explore the full potential of baicalin in drug development and clinical practice.

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