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Elsevier

Academic Press

  • The Vaccine Book

    New Insights, Approaches, and Technologies
    • 3rd Edition
    • Fabio Bagnoli + 2 more
    • English
    The Vaccine Book: New Insights, Approaches and Technologies, Third Edition provides comprehensive information on the current and future world of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases such as AIDS, tuberculosis, and malaria. Edited by a new, highly experienced team of editors, the 3rd edition provides new approaches, design, and vaccine platform tools to develop vaccines quicker.This new edition is fully updated and designed for students, researchers, public health offcials, and all others interested in increasing their understanding of vaccines.

  • Innovation in Emergency Medicine

    Technology Development and Commercialization Handbook
    • 1st Edition
    • Nancy Patterson + 3 more
    • English
    Innovation in Emergency Medicine: Technology Development and Commercialization Handbook is a step-by-step guide to emergency medicine technology innovation reflecting recent trends of industry globalization and value-conscious healthcare. Written by a team of medical, engineering, and business experts, the authors provide a comprehensive resource that leads engineers, clinicians, students, researchers, and entrepreneurs through a clear process for the identification, invention, and implementation of new solutions. Case studies on innovative products from around the world, successes and failures, practical advice, and end-of-chapter 'Getting Started' sections encourage readers to learn from real projects and apply important lessons to their own work. This new volume in the Clinical and Medical Innovation Series will be of interest to every biomedical engineer and those working in emergency medicine who has ever had a good idea for an invention but does not know where and how to start bringing it to the bedside.

  • Pharmaceutical QbD with Design of Experiments

    Statistical Tools and Applications in Drug Delivery Systems
    • 1st Edition
    • Khushwant Yadav
    • English
    Pharmaceutical QbD with Design of Experiments: Statistical Tools and Applications in Drug Delivery Systems offers comprehensive coverage of best practices in pharmaceutical manufacturing. The first section discusses the principles and basics of Quality by Design (QbD). Part two covers the foundational statistical principles and tools for the Design of Experiments (DoE). Section three is dedicated to the applications of QbD for conventional formulations. The next section provides ample coverage of applications to Novel Drug Delivery Systems (NDDS), including micro and nano-particles. The final section discusses the application of QbD for the optimization of pharmaceutical processes and equipment.Researcher... in pharmaceutical manufacturing will benefit from this thorough statistical review, while students in this field will gain practical insights the experienced chapter authors provide in case studies. Industry professionals can find solutions to their particular problems within the insights and strategies shared in this book.

  • Melanin-Concentrating Hormone

    From Metabolism to Sleep Disorders
    • 1st Edition
    • Jackson C. Bittencourt + 1 more
    • English
    Melanin-Concentratin... Hormone: From Metabolism to Sleep Disorders, the latest volume in the Molecular Mediators in Health and Disease series, offers a comprehensive understanding of this multifunctional peptide. The book covers a wide range of topics, including molecular biology of MCH, MCH in organ function, pharmacology, and MCH in disease. Recent developments in MCH imaging and pharmacological modulation are explored, along with the impact of MCH in psychiatric and neurodegenerative disorders and its role in the neuroimmunological modulation of vitiligo. Additionally, MCH is considered in the context of reproductive behavior, sleep, cognition, memory, and peripheral function.The book also explores MCH across various species such as humans, reptiles, non-primate mammals and teleosts. This is an ideal reference for researchers working with MCH across the fields of cell biology, molecular biology, pharmacology, neuroscience, endocrinology, and beyond.

  • Pain Conditions of the Head and Face

    A Practical Guide to Diagnosis and Management
    • 1st Edition
    • Anat Galor + 1 more
    • English
    Pain Conditions of the Head and Face: A Practical Guide to Diagnosis and Management provides a user-friendly guide on diagnosing and managing common head and facial pain conditions using new methods and therapies. The book contains practical information, reviewing epidemiology, presenting key features, contributing mechanisms, and including treatment algorithms for common pain conditions of the head and face. Focus is given to aspects of disease that are novel and evolving, and all conditions are discussed within the framework of the latest advances in research and patient care.Doctors seeking to ameliorate their patients’ pain from such maladies as (among many others) neuropathic ocular pain, trigeminal neuralgia, herpetic neuralgia, temporomandibular disorders, burning mouth disorder, and neuropathic ear pain will require no other book to identify their patients’ illnesses and make sure they receive the care they need.

  • Brain Point-of-Care Ultrasound

    Practical Guide and Protocols
    • 1st Edition
    • Camilo N. Rodríguez + 6 more
    • English
    Brain Point-of-Care Ultrasound: Practical Guide and Protocols explores brain hemodynamics and parenchyma examination, providing an orderly and protocolized approach that facilitates individualized clinical decisions with ease. Covering ultrasound configuration, in-depth anatomical knowledge, and advanced parameters, this guide aims to integrate brain ultrasound seamlessly into the Point-of-Care Ultrasound (POCUS) modality, addressing the critical need for comprehensive patient assessment. From basic principles to specialized clinical situations, each section of this guide is meticulously crafted to empower practitioners with practical insights. Chapters explore Doppler spectral wave interpretation, angle correction nuances, autoregulation dynamics, and non-invasive pressure estimations, among others, thus enabling precise monitoring and targeted decision-making. With a focus on integration across disciplines and specialties, this book bridges the gap between classical pathology and contemporary practice, positioning brain ultrasound as a pivotal tool in the armamentarium of modern critical care.

  • Moving Towards Fully Autonomous and Cost-Effective Surgical Robotic Systems with AI

    • 1st Edition
    • Tawanda Mushiri + 3 more
    • English
    Moving Towards Fully Autonomous and Cost-Effective Surgical Robotic Systems with AI offers advanced insights into how AI can be used to optimize the design, manufacturing, and clinical application of these systems. It covers a wide range of topics, including the introduction of surgical robotic systems design and the presentation of a fully autonomous surgical robotic system for minimally invasive surgery. Advanced medical imaging techniques integrated with surgical robots are discussed to enhance surgical precision and safety. The book also highlights the application of machine learning and deep learning models in robotic-assisted surgery, with the development of novel algorithms for autonomous surgical robots. Various AI approaches for optimizing surgical robotic systems and the design considerations for manufacturing and assembly are examined. Additionally, the book includes a thorough analysis of the life cycle and economic aspects of surgical robotic systems, as well as risk assessment and evaluation methods. The final chapters address ethics considerations and explore future enhancements in the realm of fully autonomous surgical robotic systems. Overall, this book aims to contribute to the technical understanding, design aspects, and ethical dimensions of surgical robotics, promoting safer and more efficient surgical procedures.

  • Social Determinants of Health in Surgery

    Research Methods and Clinical Review
    • 1st Edition
    • Steven A. Toms + 4 more
    • English
    Social Determinants of Health in Surgery: Research Methods and Clinical Review is a groundbreaking resource dedicated to examining the role of social determinants within surgical care. This book is designed for surgical trainees, healthcare providers, researchers, and policy administrators, offering a thorough exploration of how social factors impact surgical outcomes and practice. Featuring a detailed analysis of eleven key domains, it addresses the challenges and opportunities of integrating social determinants into surgical research and practice. The text provides essential guidance for those seeking to understand and improve patient outcomes through a broader, community-driven lens.In addition to its comprehensive coverage, the book delves into specialized topics such as big data analytics, ethical considerations, global health perspectives, pediatric surgical care, and clinical applications for research. It presents methodological guidance, including valuable tips and common pitfalls useful for readers at any stage of their surgical careers. The book also offers an in-depth review of social determinants research across ten major surgical specialties, highlighting significant trends, key studies, and current gaps in knowledge. Case studies and reflective interviews from experienced clinicians further enrich the reader’s understanding.

  • Tourette Syndrome and Other Tic Disorders

    • 1st Edition
    • Mariam Hull
    • English
    The Neuroscience of Tourette's Syndrome and Other Tic Disorders provides a foundation of the latest research into tic disorders and the brain, as well as including a comprehensive framework for the evaluation of tics. Authors across multiple specialties present the most thorough and latest knowledge of Tourette syndrome to include underlying pathophysiology, clinical presentation, how to differentiate it from other tic disorders, particularly functional tics. Clinical case studies will also feature throughout to outline challenging cases with expert commentary on evaluation and management strategies.

  • Introduction to Structural Bioinformatics

    • 1st Edition
    • Yang Zhang + 2 more
    • English
    Introduction to Structural Bioinformatics offers a complete overview on the fundamental concepts and methodologies of structural bioinformatics and computational structural biology. The book is divided into three sections, beginning with a discussion of the key principles of bioinformatics and fundamental aspects, including bioinformatics databases, multiple sequence alignment, and machine learning. Section two then moves on to structural bioinformatics, where topics include Monte Carlo simulation, protein structure prediction, RNA structure prediction, and protein design. The final section of the book focuses on experimental structural determination, where chapters focus on techniques including X-ray crystallography, nuclear magnetic resonance and cryo-electron microscopy. This is an ideal guide on key principles, methods, and the most up-to-date developments across structural bioinformatics and computational structural biology. It will be a comprehensive reference for postgraduate students, instructors, and researchers working in these and adjacent subjects.

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