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Elsevier

Academic Press

  • Hereditary Syndromes Associated with Endocrine Tumors

    • 1st Edition
    • Volume 134
    • English
    Volume 134, Hereditary Syndromes Associated with Endocrine Tumors, provides a comprehensive and up-to-date overview of the genetic, molecular, clinical, diagnostic, and therapeutic aspects of inherited endocrine neoplasia syndromes. Over the past two decades, remarkable advances in genomics, molecular diagnostics, and precision medicine have transformed the understanding and management of hereditary endocrine tumor syndromes, enabling earlier diagnosis, individualized surveillance strategies, targeted therapies, and improved patient outcomes. This volume brings together contributions from internationally recognized experts to review the current state of knowledge on both well-established and emerging hereditary syndromes affecting the endocrine system. The chapters cover the genetic basis, genotype–phenotype correlations, clinical manifestations, screening recommendations, multidisciplinary management, and future therapeutic perspectives for syndromes predisposing to tumors of the adrenal glands, pituitary, thyroid, parathyroid, pancreas, and neuroendocrine tissues. Special emphasis is placed on recent discoveries in cancer predisposition genes, advances in molecular pathology, the integration of next-generation sequencing into clinical practice, and the implications of hereditary cancer syndromes for patients and their families.

  • Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases

    • 1st Edition
    • Riccardo De Robertis
    • English
    Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases addresses the critical need for detailed comparisons between advanced ultrasound (US) techniques and CT/MRI findings in the evaluation of liver diseases. While many books exist, few provide the in-depth analysis and practical guidelines necessary for accurate diagnosis and effective treatment planning. This book fills that gap, offering a multiparametric approach to the assessment of fibrotic and steatotic liver diseases. Inside, readers will find essential topics such as indications for liver US in diffuse liver diseases, advanced Ultrasound techniques for assessing liver fibrosis and steatosis, and the correlation between US, CT, and MRI findings.Key chapters cover the basics of liver ultrasound, conventional Doppler and microvascular flow imaging, ultrasound elastography, and the quantification of liver steatosis. Additionally, the book explores cutting-edge topics like artificial intelligence in liver ultrasound and the application of US in pediatric patients. Contributions from leading experts in the field ensure that each chapter provides valuable insights and practical advice. This is an indispensable resource for scientists, researchers, and clinicians alike. It offers clear guidelines on performing liver ultrasounds, understanding and interpreting results, and making informed comparisons with CT and MRI findings.

  • Theory of Probability and Statistics

    Solved Problems and Exercises
    • 1st Edition
    • Humbat Aliyev + 2 more
    • English
    Theory of Probability and Statistics: Solved Problems and Exercises is a comprehensive and practice-oriented textbook designed for undergraduate and graduate students seeking a clear, rigorous, and intuitive understanding of probability and statistical inference. Unlike many existing titles that either lean too heavily on theory or focus mostly on computations, this book bridges the gap by integrating conceptual foundations with problem-solving techniques and real-world applications. Each chapter progresses from essential theory to fully-worked examples, followed by a rich set of exercises that reinforce learning and promote mastery.Theory of Probability and Statistics: Solved Problems and Exercises offers significant benefits to its readers: streamlined explanations of fundamental concepts, step-by-step derivations, visual interpretations where helpful, and numerous solved problems that demonstrate how abstract principles translate into practical statistical tools. Topics span classical probability, random variables, distributions, limit theorems, estimation, hypothesis testing, regression, non-parametric methods, and modern extensions relevant to data science. This book provides a fresh, accessible approach that maintains mathematical rigor while remaining student-friendly, making it ideal for university courses, self-study, and exam preparation. By blending theory with extensive solved exercises, it fills a growing demand for a unified, application-driven text tailored to contemporary learners.

  • Starch-Based Edible Films and Coatings in Food Applications

    Innovations, Challenges, and Limitations
    • 1st Edition
    • Seid Reza Falsafi + 2 more
    • English
    Starch-Based Edible Films and Coatings in Food Applications: Innovations, Challenges, and Limitations addresses the urgent need for sustainable packaging solutions in the food industry. This book targets the information needs and daily challenges faced by college and postgraduate students, university scholars, researchers, food scientists, and industry professionals working with starch-based edible films and coatings. It provides a comprehensive overview of the latest innovations, current limitations, and ongoing challenges, supporting both academic research and practical industrial applications. The book is structured into four main sections. Section I covers the production of starch-based edible films, detailing native and modified starches, preparation mechanisms, and factors influencing film properties, as well as active, intelligent, and reinforced films. Section II presents recent applications in preserving fresh produce, animal products, and processed foods. Section III reviews current and advanced analytical techniques for characterizing these films. Section IV examines cutting-edge innovations, including nanotechnology and 3D printing, and discusses existing limitations and future challenges.Starch-Ba... Edible Films and Coatings in Food Applications: Innovations, Challenges, and Limitations is a valuable resource for graduate students, researchers, and food technologists. It offers essential knowledge on manufacturing, properties, safety, and market trends, facilitating the development of innovative and sustainable food packaging solutions.

  • Diet as Complementary Treatment to Cancer Prevention and Therapy

    • 1st Edition
    • Michael N.A. Eskin + 2 more
    • English
    Diet as Complementary Treatment to Cancer Prevention and Therapy explores the role of nutrition in the prevention and treatment of cancer. The book features in-depth chapters on various cancers including liver, cervical, thyroid, esophageal, pancreatic, and oral while detailing specific dietary strategies that may mitigate risk and support therapeutic efficacy. Additionally, it addresses the significant influence of the human microbiome on cancer dynamics and highlights the promising field of metabolomics as it pertains to future cancer research. Contributions from leading experts across the fields of food science, nutrition, pharmacology, and cancer research provide current and practical applications.This comprehensive resource equips healthcare professionals with the knowledge necessary to incorporate dietary considerations into cancer prevention and treatment protocols effectively.

  • The Zebrafish Model of Neurodegenerative Disorders

    Knowing the Unknown
    • 1st Edition
    • Wael Mohamed
    • English
    The Zebrafish Model of Neurodegenerative Disorders: Knowing the Unknown reveals a ground-breaking method for decoding neurodegenerative disorders such as Parkinson's, Alzheimer's, ALS, and Huntington's through the lens of the zebrafish. This volume bridges the divide between fundamental science and clinical innovation, demonstrating how the genetic malleability, transparent embryos, and conserved neural pathways of zebrafish provide unparalleled insights into neurodegeneration. It illustrates the potential to uncover concealed pathological mechanisms, expedite drug discovery, and surmount the translational failings that impede current research using this gold-standard model species. Featuring contributions from global experts, this volume is systematically structured into five topical sections for ease of navigation. These sections explore the role of cutting-edge tools such as CRISPR-Cas9, AI-driven phenotyping, and high-throughput drug screening in the study of α-synuclein aggregation in Parkinson's Disease and amyloid-β toxicity in Alzheimer's Disease. The volume offers real-world applications, comparative analyses of zebrafish and mammalian models, and actionable protocols that translate zebrafish discoveries to clinical trials. The Zebrafish Model of Neurodegenerative Disorders is designed to empower researchers, clinicians, and healthcare professionals by addressing existing gaps in knowledge, particularly fragmentation in protocols and the translational disconnect between preclinical models and human trials. By fostering an integrated understanding of zebrafish as a model for neurodegeneration, it enhances research reproducibility, accelerates drug discovery, and promotes ethical, scalable research practices. Whether used as a teaching resource or a reference for experimental design, this volume offers invaluable insights to advance the understanding and treatment of devastating neurodegenerative diseases.

  • Bioinformatics, Computational Biology, and Multi-Omics–Driven Probiotic Design for Gut Microbiome Engineering

    • 1st Edition
    • Naheed Mojgani + 3 more
    • English
    Bioinformatics, Computational Biology, and Multi Omics–Driven Probiotic Design for Gut Microbiome Engineering presents an interdisciplinary framework for applying artificial intelligence to microbiome science, probiotic development, and personalized nutrition. The book integrates bioinformatics, computational biology, and clinical insight to address current challenges in gut microbiome research and translation. The volume covers AI driven microbiome profiling, multi omics integration, computational modeling of host–microbe interactions, and predictive analytics. It progresses from foundational concepts to advanced applications, including AI assisted probiotic design, gut–brain axis research, regulatory considerations, and real world case studies supporting translational and clinical relevance. The book equips bioinformaticians, translational microbiome researchers, and clinician scientists with actionable methodologies, conceptual clarity, and validated examples. It supports evidence based decision making, accelerates translational research, and bridges discovery science with implementation in personalized nutrition and probiotic innovation.

  • Wilson and Mulcahy’s Prosthetic Urology

    A Comprehensive Guide to Surgery for Erectile Dysfunction and Male Incontinence
    • 1st Edition
    • Jay Simhan + 1 more
    • English
    Wilson and Mulcahy’s Prosthetic Urology: A Comprehensive Guide to Surgery for Erectile Dysfunction and Male Incontinence is a comprehensive reference that covers the surgical management of erectile dysfunction and male incontinence.This book's chapters cover a wide range of topics, including the history of penile prostheses, practice considerations, patient selection, placement techniques for malleable and inflatable penile prostheses, management of complications, and infection prevention and management. Additionally, specialized topics such as managing Peyronie's disease, priapism, and penile prosthesis placement in transgender patients are also addressed.Written by esteemed experts in the field, this reference offers valuable insights and guidance for healthcare professionals. Whether you are a practicing prosthetic urologist, a trainee looking to enhance your skills, or a device manufacturer aiming to improve surgical quality, this essential reference will elevate your knowledge and expertise.Tibor Imley's cover photo features Dr. Wilson and Dr. Mulcahy, after whom this title is named. This book honors their pioneering contributions to prosthetic urology.

  • A Comprehensive and Practical Guide in Clinical Trials

    • 2nd Edition
    • Brenda Wright
    • English
    The Comprehensive and Practical Guide in Clinical Trials, Second Edition offers a thorough update to the foundational handbook on clinical trial conduct. It reflects the evolving landscape of clinical research since 2017, incorporating new regulatory guidelines, innovations in device trials, and the shift to electronic data capture and management. This resource addresses the needs of clinical trial staff by detailing processes essential to successful trial execution. Covering all aspects of clinical research, the book includes chapters on trial phases, site selection, regulatory requirements, contracts, protocol development, informed consent, and data management. New chapters focus on project management, electronic source documents, and pharmacy operations. Each chapter integrates practical tools such as checklists, templates, and case studies to facilitate understanding and application. This handbook uniquely supports the entire clinical trial team—including investigators, coordinators, pharmacists, data managers, and regulatory personnel—by clarifying roles and responsibilities and illustrating how their tasks interconnect. Its accessible style and comprehensive scope make it an indispensable guide for planning, conducting, and closing clinical trials effectively and in compliance with international standards.

  • Capsule Endoscopy in Pediatric Patients from Theory to Practice

    • 1st Edition
    • Thomas M. Attard
    • English
    Capsule Endoscopy in Pediatric Patients from Theory to Practice is a practical and authoritative guide that empowers pediatric gastroenterologists, physicians, and trainees to navigate the complexities of Video Capsule Endoscopy (VCE) in children. With a focus on bridging knowledge gaps and providing practical insights, this book offers updated information on understanding and utilizing VCE in the pediatric population. The book covers the background and technical aspects of VCE, including guidance on setting up a pediatric VCE service and an overview of indications and limitations. It delves into practical aspects such as preprocedural preparation, artifact reduction techniques, and management of capsule retention. By exploring VCE in various disease conditions such as inflammatory bowel disease, gastrointestinal bleeding, hereditary polyposis syndromes, and chronic abdominal pain, readers gain a comprehensive understanding of diagnosis, surveillance, and management. Special content elements, including key terms, case studies, and a timeline of recent advances, enhance the learning experience. This essential resource empowers readers to optimize patient care, make informed decisions, and confidently navigate the realm of VCE in children.

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