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Elsevier

Academic Press

  • Formulation and Device Lifecycle Management of Biotherapeutics

    A Guidance for Researchers and Drug Developers
    • 1st Edition
    • Beate Bittner + 1 more
    • English
    Today, the pressure on healthcare costs and resources is increasing, and especially for biopharmaceuticals that require parenteral administration, the inherent complex and invasive dosing procedure adds to the demand for efficient medical management. In light of the COVID-19 pandemic the value of drug delivery technologies in enabling a flexible care setting is broadly recognized. In such a setting, patients and their caregivers can choose the place of drug administration based on individual preferences and capabilities. This includes not only dosing in the clinic but also supervised at-home dosing and self-administration for eligible patients. Formulation and Device Lifecycle Management of Biotherapeutics: A Guidance for Researchers and Drug Developers covers the various aspects of improving drug delivery of biological medicines with the ultimate goal to reduce dosing complexity associated with parenteral administration and, thus, enhance patient experience and drug administration-relat... healthcare capacity. The target audience are multidisciplinary researchers and drug developers in the pharmaceutical industry, biotech companies, and academia involved in formulation and device development. This includes pharmacology and medical experts in charge of generating nonclinical and clinical data to support approval of novel dosing regimens, and drug delivery scientists and engineers responsible for technical particulars of product optimizations. Moreover, professionals in market access and commercial functions are expected to benefit from the discussions about the impact of patient and healthcare provider needs and country-specific reimbursement models on realizing a truly convenient and cost and resource efficient drug delivery solution.

  • Membrane Proteins

    • 1st Edition
    • Volume 128
    • Rossen Donev
    • English
    Membrane Proteins, Volume 128 in the Advances in Protein Chemistry and Structural Biology series highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Artificial Intelligence for Healthcare Applications and Management

    • 1st Edition
    • Boris Galitsky + 1 more
    • English
    Artificial Intelligence for Healthcare Applications and Management introduces application domains of various AI algorithms across healthcare management. Instead of discussing AI first and then exploring its applications in healthcare afterward, the authors attack the problems in context directly, in order to accelerate the path of an interested reader toward building industrial-strength healthcare applications. Readers will be introduced to a wide spectrum of AI applications supporting all stages of patient flow in a healthcare facility. The authors explain how AI supports patients throughout a healthcare facility, including diagnosis and treatment recommendations needed to get patients from the point of admission to the point of discharge while maintaining quality, patient safety, and patient/provider satisfaction. AI methods are expected to decrease the burden on physicians, improve the quality of patient care, and decrease overall treatment costs. Current conditions affected by COVID-19 pose new challenges for healthcare management and learning how to apply AI will be important for a broad spectrum of students and mature professionals working in medical informatics. This book focuses on predictive analytics, health text processing, data aggregation, management of patients, and other fields which have all turned out to be bottlenecks for the efficient management of coronavirus patients.

  • Hormones

    • 4th Edition
    • Gerald Litwack
    • English
    Hormones, Fourth Edition provides a report on the field of human hormones viewed in light of our current understanding of cellular and subcellular architecture, along with the molecular details of their modes of action. Comprehensive information about hormone action on canonical and non-canonical signaling pathways at cellular and subcellular level and effects on architecture and function of organ systems are discussed. All chapters in this new edition have been completely updated to cover advances in endocrinology research, which has expanded significantly in the last few years. Vast coverage of hormones not previously covered and newly discovered aspects of hormone action are also included. This new fourth edition is intended to be used by advanced undergraduates and graduate students in the biological sciences. It will also provide useful background information for health professionals, clinicians and researchers in the field of endocrinology, metabolism and biochemistry.

  • Understanding Cancer

    From Basics to Therapeutics
    • 1st Edition
    • Buddhi Prakash Jain + 1 more
    • English
    Understanding Cancer: From Basics to Therapeutics presents both basic concepts and research prospects in the field of cancer biology. This book summarizes the fundamental aspects of cancer and presents a detailed description of molecular aspects as well as treatment and therapeutics for patients. The book is divided into three parts: the first part deals with the basics of cancer, including etiology and medical diagnosis; the second part explores the molecular mechanisms associated with cancer, focusing on cell cycle and apoptosis, cell metabolism, gene regulation, epigenetics, and stem cells; and the third part is dedicated to therapeutics, discussing chemo and radiotherapies, gene, hormone, herbal, and immunotherapies. It is a valuable resource for cancer researchers, oncologists, graduate students, and biomedical researchers who need to understand the fundamental topics related to cancer to apply to their research work or clinical setting.

  • Advances in Agronomy

    • 1st Edition
    • Volume 171
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 171, the latest release in this leading reference, contains a variety of updates and new advances in the field, including updates on Elevated CO2 in Semi-arid Cropping Systems: A Synthesis of Research from the Australian Grains Free Air CO2 Enrichment (AGFACE) Research Program, Simultaneous Effects of Legume Cultivation on Carbon and Nitrogen Accumulation in Soil, Growing Small Grains Organically in the Semiarid West: A Review of Markets and Management Practices to Optimize Productivity and Sustainability, Principles and Applications of Topography in Precision Agriculture, Retention of Heavy Metals by Dredged Sediments and their Management Following Land Application, and more. Other chapters focus on Genetic Diversity for Developing Climate-resilient Wheats to Achieve Food Security Goals and A Century of Subclover: Lessons for Sustainable Intensification from a Historical Review of Innovations in Subterranean Clover Seed Production.

  • Medical Device Regulations

    A Complete Guide
    • 1st Edition
    • Aakash Deep
    • English
    Medical Device Regulations: A Complete Guide describes a brief review of various regulatory bodies of major developed and developing countries around the world. The book covers the registration procedures of medical devices for pharmaceutical regulatory organizations. Sections provide guidance on dealing with the ethical considerations of medical device development, compliance with patient confidentiality using information from medical devices, the interoperability between, and among devices outside of healthcare, and the dynamics of implementation of new devices to ensure patient safety. The author brings forth relevant issues, challenges and demonstrates how management can foster increased clinical and non-clinical relations to enhance patient outcomes and the bottom-line by demystifying the regulatory impact on operational requirements.

  • Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications - Part A

    • 1st Edition
    • Volume 186
    • English
    Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications, Volume 185, Part A represents the collation of chapters written by eminent scientists worldwide. Chapters in this updated release include An introduction to microfluidics and their applications, Design and fabrication of Micro/Nanofluidics devices and systems, Detection and separation of proteins using Micro/Nanofluidics devices, Micro/Nanofluidics devices for DNA/RNA detection and separation, Paper based microfluidics a forecast towards the most affordable and rapid point-of-care devices, Paper based micro/Nanofluidics devices for biomedical applications, Advances of Microfluidics Devices and their Applications in Personalized Medicine, and much more. Additional chapters cover Microfluidics for single cell analysis, Fluorescence Based Miniaturized Microfluidic and Nanofluidic Systems for Biomedical Applications, Active Matter Dynamics in Confined Microfluidic Environments, Challenges and opportunities in micro/nanofluidics and lab-on-a-chip, and Paper-microfluidic signal-enhanced immunoassays.

  • New Frontiers and Applications of Synthetic Biology

    • 1st Edition
    • Vijai Singh
    • English
    New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more. This book is a good source for not only researchers in designing synthetic biology, but also for researchers, students, synthetic biologists, metabolic engineers, genome engineers, clinicians, industrialists, stakeholders and policymakers interested in harnessing the potential of synthetic biology in many areas.

  • Photosynthesis in Action

    Harvesting Light, Generating Electrons, Fixing Carbon
    • 1st Edition
    • Alexander Ruban + 2 more
    • English
    Photosynthesis in Action examines the molecular mechanisms, adaptations and improvements of photosynthesis. With a strong focus on the latest research and advances, the book also analyzes the impact the process has on the biosphere and the effect of global climate change. Fundamental topics such as harvesting light, the transport of electronics and fixing carbon are discussed. The book also reviews the latest research on how abiotic stresses affect these key processes as well as how to improve each of them. This title explains how the process is flexible in adaptations and how it can be engineered to be made more effective. End users will be able to see the significance and potential of the processes of photosynthesis. Edited by renowned experts with leading contributors, this is an essential read for students and researchers interested in photosynthesis, plant science, plant physiology and climate change.

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