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    • Chemical Biology of the Genome

      • 1st Edition
      • May 14, 2021
      • Siddhartha Roy + 1 more
      • English
      • Paperback
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      • eBook
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      Chemical Biology of the Genome provides a comprehensive overview of essential concepts and principles of genomic and epigenomics dynamics as explored through the lens of chemical biology. Key examples and case studies illustrate chemical biology methods for study and analysis of the genome and epigenome, with an emphasis on relevance to physiological and pathophysiological processes and drug discovery. Authors and international leaders in biochemical studies of the genome, Drs. Siddhartha Roy and Tapas Kundu, adopt an integrated, interdisciplinary approach throughout, demonstrating how fast evolving chemical and mass-scale sequencing tools are increasingly used to interpret biochemical processes of the genome. Later sections discuss chemical modifications of the genome, DNA sequence recognition by proteins and gene regulation, GWAS and EpiGWAS studies, 3D architecture of the genome, and functional genome architecture. In-depth, discovery focused chapters examine intervention in gene networks using SiRNA/ShRNA, miRNA, and anti-miR, small molecule modulation of iPS, drug resistance pathways altered DNA methylation as drug targets, anti-miR as therapeutics, and nanodelivery of drugs.

    • Energy Storage Devices for Renewable Energy-Based Systems

      • 2nd Edition
      • May 13, 2021
      • Nihal Kularatna + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 0 7 7 8 9
      • eBook
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      Energy Storage Devices for Renewable Energy-Based Systems: Rechargeable Batteries and Supercapacitors, Second Edition is a fully revised edition of this comprehensive overview of the concepts, principles and practical knowledge on energy storage devices. The book gives readers the opportunity to expand their knowledge of innovative supercapacitor applications, comparing them to other commonly used energy storage devices. With new application case studies and definitions, this resource will strengthen your understanding of energy storage from a practical, applications-based point-of-view without requiring detailed examination of underlying electrochemical equations. Users will learn about various design approaches and real-time applications of ESDs. Electronic engineering experts and system designers will find this book useful to deepen their understanding on the application of electronic storage devices, circuit topologies, and industrial device data sheets to develop new applications. The book is also intended to be used as a textbook for masters and doctoral students who want to enhance their knowledge and understanding the concepts of renewable energy sources and state-of-the-art ESDs.

    • Fluorescent Probes

      • 1st Edition
      • Volume 48
      • May 13, 2021
      • English
      • Hardback
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      • eBook
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      Fluorescent Probes, Volume 48 in the Methods in Microbiology series, highlights new advances in the field, with this new volume presenting interesting chapters on important topics, including Hydrogel microarray technology as a tool for clinical diagnostics, The use of probes and bacteriophages for bacteria detection, Probes used with point-of-care microfluidic devices for pathogen detection, Methods for combining FIB/SEM with three-dimensional fluorescence microscopy using CLEM approaches, Probes and Microbes, Microbial signatures associated with cancers, Fluorescent Aptamers for Detection and Treatment of Pathogenic Bacteria and Cancer, Labelled and Unlabeled Probes for Pathogen Detection with Molecular Biology Methods and Biosensors, and much more.

    • Nematode Models of Development and Disease

      • 1st Edition
      • Volume 144
      • May 13, 2021
      • English
      • Hardback
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      • eBook
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      Nematode Models of Development and Disease, Volume 144 in the Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters surrounding Transgenerational inheritance, Oscillatory expression and function, Concepts and functions of small RNA pathways in C. elegans, Exploring the nuclear lamina in health and pathology using C. elegans, Cellular Plasticity, Morphogenesis, Tubulogenesis, Organogenesis forces, Programmed cell fusion in development and homeostasis, One template, two outcomes: how does the sex-shared nervous system generate sex-specific behaviors?, Metabolic Cellular Coordination of Gene-Environment Interactions, and much more. Other chapters cover Chemical and physical cues and micro-evolution in early embryogenesis, Innate immunity, Sex and Death, Dendrites maturation, axonal growth and extracellular glycoproteins, Autophagocytosis, Spermatogenesis, and the developmental and physiological roles of phagocytosis in Caenorhabditis elegans.

    • Biochemical and Molecular Basis of Pediatric Disease

      • 5th Edition
      • May 13, 2021
      • Edward C.C. Wong + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 7 9 6 2 8
      • eBook
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      Biochemical and Molecular Basis of Pediatric Disease, Fifth Edition has been a well-respected reference in the field for decades. This revision continues the strong focus on understanding the pathogenesis of pediatric disease, emphasizing not only the important role of the clinical laboratory in defining parameters that change with the disease process, but also the molecular basis of many pediatric diseases.

    • Advances in Immunology

      • 1st Edition
      • Volume 149
      • May 13, 2021
      • Frederick W. Alt
      • English
      • Hardback
        9 7 8 0 1 2 8 2 4 5 9 7 2
      • eBook
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      Advances in Immunology, Volume 149, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.

    • Translational Bioinformatics in Healthcare and Medicine

      • 1st Edition
      • May 13, 2021
      • English
      • Paperback
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      • eBook
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      Translational Bioinformatics in Healthcare and Medicine offers an overview of main principles of bioinformatics, biological databases, clinical informatics, health informatics, viroinformatics and real-case applications of translational bioinformatics in healthcare. Written by experts from both technology and clinical sides, the content brings together essential knowledge to make the best of recent advancements of the field. The book discusses topics such as next generation sequence analysis, genomics in clinical care, IoT applications, blockchain technology, patient centered interoperability of EHR, health data mining, and translational bioinformatics methods for drug discovery and drug repurposing. In addition, it discusses the role of bioinformatics in cancer research and viroinformatics approaches to counter viral diseases through informatics. This is a valuable resource for bioinformaticians, clinicians, healthcare professionals, graduate students and several members of biomedical field who are interested in learning more about how bioinformatics can impact in their research and practice.

    • Cultured Microalgae for the Food Industry

      • 1st Edition
      • May 12, 2021
      • Tomas Lafarga + 1 more
      • English
      • Paperback
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      Cultured Microalgae for the Food Industry: Current and Potential Applications is a comprehensive reference that addresses the current applications and potential uses of microalgae and microalgae-derived compounds in the food industry. The book explores the different steps of the subject, from strain selection and cultivation steps, to the assessment of the public perception of microalgae consumption and the gastronomical potential of this innovative resource. Readers will find coverage of microalgae biology, common and uncommon algae species, cultivation strategies for food applications, novel extraction techniques, safety issues, regulatory issues, and current market opportunities and challenges. This title also explores the gastronomic potential of microalgae and reviews current commercialized products along with consumer attitudes surrounding microalgae. Covering relevant, up-to-date research as assembled by a group of contributors who are experts in their respective fields, the book is an essential reading for advanced undergraduates, postgraduates, and researchers in the microbiology, biotechnology, food science and technology fields.

    • Autonomous Robot-Aided Optical Manipulation for Biological Cells

      • 1st Edition
      • May 12, 2021
      • Mingyang Xie
      • English
      • Paperback
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      • eBook
        9 7 8 0 1 2 8 2 3 5 9 2 8
      Autonomous Robot-Aided Optical Manipulation for Biological Cells gives a systematically and almost self-contained description of the many facets of modeling, sensing, and control techniques or experimentally exploring emerging trends in optical manipulation of biological cell in micro/nanorobotics systems. To achieve biomedical applications, reliability design, modeling, and precision control are vitally important for the development of engineering systems. With the advances in modeling, sensing, and control techniques, it is opportunistic to exploit them for the benefit of reliability design, actuation, and precision control of micro/nanomanipulati... systems to expanding the applications of robot at the micro and nano scales, especially in biomedical engineering. This book presents new techniques in reliability modeling and advanced control of robot-aided optical manipulation of biological cells systems. The book will be beneficial to the researchers within robotics, mechatronics, biomedical engineering, and automatic control society, including both academic and industrial parts.

    • Visceral Leishmaniasis

      • 1st Edition
      • May 12, 2021
      • Awanish Kumar
      • English
      • Paperback
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      • eBook
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      Visceral Leishmaniasis: Therapeutics and Vaccines describes current therapeutics, natural anti-leishmanial molecules, anti-leishmanial screening, and explores vaccine candidates and amastigote-based vaccination strategies for Leishmania. The book provides a precise view on VL, Leishmania parasite culture, host immunity and immunomodulation, natural compounds effective against VL, animal models for VL, and methodologies available for anti-leishmanial drug screening procedures against VL, as well as vaccine and vaccination-related information on Leishmaniasis. Readers will find concrete information on past and current hurdles facing vaccine development for Leishmania, along with scientific opportunities and the potential impact of vaccines, including problems encountered. The book is designed to increase the understanding of vaccines, particularly in VL, for students and researchers. Although vaccines are now available for many diseases, there are still challenges ahead for a vaccine for VL. The ideal vaccine must be safe and able to induce an immune response that is strong and effective. In a nutshell, a combination of chemotherapy (drugs) and immunoprophylaxis (vaccine) would be ideal to win the battle against VL.

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