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    • Reprogramming the Genome: Applications of CRISPR-Cas in non-mammalian systems part B

      • 1st Edition
      • Volume 180
      • April 29, 2021
      • English
      • Hardback
        9 7 8 0 3 2 3 8 5 2 9 7 5
      • eBook
        9 7 8 0 3 2 3 8 5 2 9 8 2
      Reprogramming the Genome: Applications of CRISPR-Cas in Non-mammalian Systems Part B, represents the collation of chapters written by eminent scientists worldwide. CRISPR-Cas9 system is an RNA-mediated immune system of bacteria and archaea that protects from bacteriophage infections. It is one of the revolutionized technologies to uplift biology to the next stages. It is a simple, rapid, precise, and cost-effective tool for genome editing and regulation of a wide range of organisms. It has gained scientific and public attention worldwide. This volume mainly covers insect cell line, protozoans, zebrafish, drosophila, CRISPRi, patents as well as technology transfer, and many more. This book is a key source of information available in a single volume. This book will be useful for not only beginners in genome engineering, but also students, researchers, scientists, policymakers, and stakeholders interested in harnessing the potential of reprogramming of the genomes in several areas.

    • Electronic Devices, Circuits, and Systems for Biomedical Applications

      • 1st Edition
      • April 28, 2021
      • Suman Lata Tripathi + 4 more
      • English
      • Paperback
        9 7 8 0 3 2 3 8 5 1 7 2 5
      • eBook
        9 7 8 0 3 2 3 8 5 3 6 9 9
      Electronic Devices, Circuits, and Systems for Biomedical Applications: Challenges and Intelligent Approaches explains the latest information on the design of new technological solutions for low-power, high-speed efficient biomedical devices, circuits and systems. The book outlines new methods to enhance system performance, provides key parameters to explore the electronic devices and circuit biomedical applications, and discusses innovative materials that improve device performance, even for those with smaller dimensions and lower costs. This book is ideal for graduate students in biomedical engineering and medical informatics, biomedical engineers, medical device designers, and researchers in signal processing.

    • Apoptosis in Health and Disease - Part A

      • 1st Edition
      • Volume 125
      • April 28, 2021
      • Rossen Donev
      • English
      • Hardback
        9 7 8 0 3 2 3 8 5 3 1 5 6
      • eBook
        9 7 8 0 3 2 3 8 5 3 1 6 3
      Apoptosis, or programmed cell death, is the mechanism by which cells die either physiologically or pathologically. A vast research in apoptosis has advanced our understanding of basic physiological and pathological processes occurring in cells, organs and organisms, and its role in a number of diseases. These new advanced understandings are playing a major influence in drug discovery and the introduction of new therapies that target this cell death process. These two thematic volumes 125 and 126 of the Advances in Protein Chemistry and Structural Biology focus on apoptotic responses in numerous conditions - from bacterial and parasite infections to pathological states such as oxidative stress, pulmonary hypertension, different cancer types, etc. Finally, therapeutic strategies for targeting apoptosis are also discussed.

    • iPSCs for Modeling Central Nervous System Disorders, Volume 6

      • 1st Edition
      • April 28, 2021
      • Alexander Birbrair
      • English
      • Paperback
        9 7 8 0 3 2 3 8 5 7 6 4 2
      • eBook
        9 7 8 0 3 2 3 8 5 6 4 2 3
      The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs for Modeling Central Nervous System Disorders, Volume 6 addresses how induced pluripotent stem cells can be used to model various CNS disorders. Somatic cells can be reprogrammed into　Induced pluripotent stem cells　by the expression of specific transcription factors. These cells　are transforming biomedical research in the last 15 years. The volume teaches readers about current advances in the field. This book describes the use of induced pluripotent stem cells to model several CNS diseases in vitro, enabling us to study the cellular and molecular mechanisms involved in different CNS pathologies. Further insights into these mechanisms will have important implications for our understanding of CNS disease appearance, development, and progression. In recent years, remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cell types, tissues and organs using state-of-art techniques. These advantages facilitated identification of key targets and definition of the molecular basis of several CNS disorders. This volume will cover what we know so far about the use of iPSCs to model different CNS disorders, such as: Alzheimer’s disease, Autism, Amyotrophic Lateral Sclerosis, Schizophrenia, Fragile X Syndrome, Spinal Muscular Atrophy, Rett Syndrome, Angelman syndrome, Parkinson`s Disease, Leber Hereditary Optic Neuropathy, Anorexia Nervosa, and more. The volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and neuroscience; and is contributed by world-renowned authors in the field.

    • Advances in the Study of Behavior

      • 1st Edition
      • Volume 53
      • April 27, 2021
      • Marc Naguib
      • English
      • Hardback
        9 7 8 0 1 2 8 2 4 5 8 4 2
      • eBook
        9 7 8 0 3 2 3 8 5 0 7 1 1
      Advances in the Study of Behavior, Volume 53 provides users with the latest insights in this ever-evolving field. New chapters in this release include Cooperative breeding in birds, Interactive singing in birds: What have we learned in the last 20 years? Pied babblers, Mate choice in frogs, Dogs, and Do hosts of avian brood parasites discriminate parasitic vs. predatory threats? A review.

    • Tribocorrosion

      • 1st Edition
      • April 27, 2021
      • Arpith Siddaiah + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 9 1 6 0
      • eBook
        9 7 8 0 1 2 8 1 8 9 1 7 7
      Tribocorrosion: Fundamentals, Methods, and Materials provides a balanced coverage of recent advancements in both experimental and computational areas of tribocorrosion, covering the basic concepts of tribology and electrochemistry, as well as testing set-ups, protocols, electrochemical methods, and more. It outlines experimental methods, demonstrating the different effects of material loss due to mechanical and electrochemical actions and looks at their effects in applied automotive, aerospace and biomedical settings. Standard testing protocols, tribocorrosion mechanisms in sliding contacts, and modeling and simulation techniques are all covered at length, as is bio-tribocorrosion and the best ways to prevent it.

    • Pedigree Analysis in R

      • 1st Edition
      • April 27, 2021
      • Magnus Dehli Vigeland
      • English
      • Paperback
        9 7 8 0 1 2 8 2 4 4 3 0 2
      • eBook
        9 7 8 0 1 2 8 2 4 5 6 0 6
      Pedigree Analysis in R gives an introduction to the theory of relatedness and covers a range of applications in forensic and medical genetics. The book's material was developed through teaching courses on genetic relatedness, pedigree analysis and R, and offers insights from a decade of research activities in forensic and medical genetics. The R code in the book uses the ped suite, a unified collection of packages for pedigree analysis, developed by the author. All code examples are given in full, allowing accurate reproduction of figures and results. At the end of each chapter, a selection of exercises encourages the reader to explore further and perform their own analyses.

    • Researches and Applications of Artificial Intelligence to Mitigate Pandemics

      • 1st Edition
      • April 27, 2021
      • Kauser Hameed + 2 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 0 9 5 9 4
      • eBook
        9 7 8 0 3 2 3 8 9 9 9 6 3
      Researches and Applications of Artificial Intelligence to Mitigate Pandemics: History, Diagnostic Tools, Epidemiology, Healthcare, and Technology offers readers an interdisciplinary view of state-of-art research related to the COVID-19 outbreak, with a focus on tactics employed to model the number of cases of COVID-19 (time series modeling), models employed to diagnostics COVID-19 based on images, and the panoramic of COVID-19 since its discovery and up to this book's publication. This book showcases the algorithms and models available to manage pandemic data, the role of AI, IoT and Mathematical Modeling, how to prevent and fight COVID-19, and the existing medical, social and pharmaceutical support. Chapters cover methods and protocols, the basics and history of diseases, the fast diagnosis of disease with different automated algorithms and artificial intelligence tools and techniques, the methods of handling epidemiology for mitigating the spread of disease, artificial intelligence and mathematical modeling techniques, and how mental and physical health is affected with social media usage.

    • Psychology Research Methods

      • 1st Edition
      • April 25, 2021
      • Elizabeth Brondolo
      • English
      • Paperback
        9 7 8 0 1 2 8 1 5 6 8 0 3
      • eBook
        9 7 8 0 1 2 8 1 5 6 8 1 0
      Psychology Research Methods: A Writing Intensive Approach provides instruction in critical concepts and processes in behavioral science research methods and skills in formulating and writing research papers. The book creates an experiential approach to learning, with chapters organized around the task of writing a complete APA-style research paper.The chapters consist of instructional text, excerpts from published research articles, and learning activities. The reading activities help students develop skills in reading scientific research, evaluating and analyzing scientific information, and assembling evidence to make a scientific argument. The writing activities help students to break down the process of writing a research paper into manageable and meaningful components. As students complete the chapter activities, they assemble their research paper.The book teaches research methods in a clinical context, inspired by the National Institute of Health’s Science of Behavior Change Program. Students acquire knowledge about research methods as they read research articles about behavioral health disorders, including studies about their prevalence, causes, and treatment. Teaching research methods with a clinical focus helps students appreciate the value of psychological research.Psychology Research Methods: A Writing Intensive Approach provides instruction in critical concepts and processes in behavioral science research methods and skills in formulating and writing research papers. The book creates an experiential approach to learning, with chapters organized around the task of writing a complete APA-style research paper.The chapters consist of instructional text, excerpts from published research articles, and learning activities. The reading activities help students develop skills in reading scientific research, evaluating and analyzing scientific information, and assembling evidence to make a scientific argument. The writing activities help students to break down the process of writing a research paper into manageable and meaningful components. As students complete the chapter activities, they assemble their research paper.The book teaches research methods in a clinical context, inspired by the National Institute of Health’s Science of Behavior Change Program. Students acquire knowledge about research methods as they read research articles about behavioral health disorders, including studies about their prevalence, causes, and treatment. Teaching research methods with a clinical focus helps students appreciate the value of psychological research.Psychology Research Methods: A Writing Intensive Approach provides instruction in critical concepts and processes in behavioral science research methods and skills in formulating and writing research papers. The book creates an experiential approach to learning, with chapters organized around the task of writing a complete APA-style research paper.The chapters consist of instructional text, excerpts from published research articles, and learning activities. The reading activities help students develop skills in reading scientific research, evaluating and analyzing scientific information, and assembling evidence to make a scientific argument. The writing activities help students to break down the process of writing a research paper into manageable and meaningful components. As students complete the chapter activities, they assemble their research paper.The book teaches research methods in a clinical context, inspired by the National Institute of Health’s Science of Behavior Change Program. Students acquire knowledge about research methods as they read research articles about behavioral health disorders, including studies about their prevalence, causes, and treatment. Teaching research methods with a clinical focus helps students appreciate the value of psychological research.

    • Mechanisms and Genetics of Neurodevelopmental Cognitive Disorders

      • 1st Edition
      • April 25, 2021
      • Moyra Smith
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 9 1 3 3
      • eBook
        9 7 8 0 1 2 8 2 3 2 5 2 1
      Mechanisms and Genetics of Neurodevelopmental Cognitive Disorders connects neurodevelopment with genetics and behavior to better understand the underlying factors leading to cognitive neurodevelopmental disorders. This book focuses on mechanisms of disease and follows the development of specific brain regions, functions, and gene expression to causes and processes in autism, attention deficit disorder, and learning disabilities. Topics include brain mapping, brain plasticity, epigenetics, neuroimmunology, and many other factors that influence the development of these diseases. This book will promote understanding of recent investigations and developments related to brain development from fetal life onward with specific relevance to neurodevelopmental cognitive disorders and conditions. This is an essential reference for anyone who is looking to learn more about different aspects of neurodevelopment and emerging concepts in psychiatric disorders.

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