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Academic Press

  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1st Edition
    • Volume 49
    • English
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 49 provides timely and pertinent information on a variety of timely topics, including Physical Profiles of Drug Substances and Excipients; Analytical Profiles of Drug Substances and Excipients; ADME Profiles of Drug Substances and Excipients; Methodology Related to the Characterization of Drug Substances and Excipients; and Methods of Chemical Synthesis. In addition, it includes comprehensive profiles of five drug compounds: Deferasirox, Duvelisib, Regorafenib, Ponatinib and Avanafil. Finally, the book contains a chapter on Regulation and Standardization of Herbal Drugs: Current status, Limitation, Challenge’s, and Future Prospectives.

  • Strigolactones

    Synthesis, Application and Role in Plants
    • 1st Edition
    • Gausiya Bashri + 2 more
    • English
    Strigolactones: Synthesis, Application and Role in Plants presents the current state of the science for this recently discovered class of plant hormones, offering foundational insights. The book covers the structure of natural and synthetic SLs, synthesis, transport, signaling, and their application, role in the growth and development of plants like seed germination, root growth, and stem branching plant architecture. Further, the crosstalk of SLs with other plant hormones and signaling molecules are discussed. Finally, the role of SLs in plant defense systems, particularly in biotic and abiotic stresses, heavy metals, salt, temperature, radiation, pesticide drought, and flood stress on plants.Concluding with the latest discoveries, future perspectives, and challenges in plant biology, this book will be a valuable reference for those in plant and agricultural sciences.

  • Aging

    How Aging Works, How We Reverse Aging, and Prospects for Curing Aging Diseases
    • 1st Edition
    • Michael Fossel
    • English
    Aging: How Aging Works, How We Reverse Aging, and Prospects for Curing Aging Diseases explains the process of aging beyond mere entropy, exposing it as a complicated and dynamic process that undercuts maintenance and permits age-related disease. With a deeper understanding of the aging process, intervention becomes both easy to understand and clinically feasible.With a solid academic approach, this proposed book builds upon the substantial work published over the past 20 years, citing the newest data, up-to-date models based upon that data, and the implications for improved clinical intervention, including recent developments in gene and cell therapy. Coverage of age-related diseases includes neurodegenerative, cardiovascular, bone and joint, immune system, renal, pulmonary, and skin aging. Future directions of the field focus on interventions, including a summary of previous attempts to intervene in aging and age-related disease, the status of current research, and proposed biotech interventions, as well as their potential obstacles, risks, and benefits. This is the perfect reference for scientists, clinicians, and researchers interested in the translational research opportunities such as drug discovery, pharmacogenetics, and experimental therapeutics, not only summarizing where the field stands, but giving a clear and cogent view of where clinical medicine is going in the next decade.

  • A Biologist’s Guide to Artificial Intelligence

    Building the foundations of Artificial Intelligence and Machine Learning for Achieving Advancements in Life Sciences
    • 1st Edition
    • Ambreen Hamadani + 3 more
    • English
    A Biologist’s Guide to Artificial Intelligence: Building the Foundations of Artificial Intelligence and Machine Learning for Achieving Advancements in Life Sciences provides an overview of the basics of Artificial Intelligence for life science biologists. In 14 chapters/sections, readers will find an introduction to Artificial Intelligence from a biologist’s perspective, including coverage of AI in precision medicine, disease detection, and drug development. The book also gives insights into the AI techniques used in biology and the applications of AI in food, and in environmental, evolutionary, agricultural, and bioinformatic sciences. Final chapters cover ethical issues surrounding AI and the impact of AI on the future.This book covers an interdisciplinary area and is therefore is an important subject matter resource and reference for researchers in biology and students pursuing their degrees in all areas of Life Sciences. It is also a useful title for the industry sector and computer scientists who would gain a better understanding of the needs and requirements of biological sciences and thus better tune the algorithms.

  • Sequences and the de Bruijn Graph

    Properties, Constructions, and Applications
    • 1st Edition
    • Tuvi Etzion
    • English
    Sequences and the de Bruijn Graph: Properties, Constructions, and Applications explores the foundations of theoretical mathematical concepts and their important applications to computer science, electrical engineering, and bioinformatics. The book introduces the various concepts, ideas, and techniques associated with the use of the de Bruijn Graph, providing comprehensive coverage of sequence classification, one-dimensional and two-dimensional properties, constructions, and interconnection networks. This book is suitable for researchers, graduate students, professors, and professionals working in the fields of applied mathematics, electrical engineering, computer science, and bioinformatics.The de Bruijn graph was defined in 1946 to enumerate the number of closed sequences where each n-tuple appears exactly once as a window in a sequence. Through the years, the graph and its sequences have found numerous applications – in space technology, wireless communication, cryptography, parallel computation, genome assembly, DNA storage, and microbiome research, among others.

  • Pediatric and Adult Celiac Disease

    A Clinically Oriented Perspective
    • 1st Edition
    • Gino Roberto Corazza + 3 more
    • English
    Pediatric and Adult Coeliac Disease: A Clinically Oriented Perspective provides an up-to-date, comprehensive, and critical overview of coeliac disease, its complications, and related disorders. The book covers epidemiological, pathogenetic, diagnostic, and treatment issues, including pediatric and adult cases, with a broad and international view. This is the perfect reference for researchers dedicated to advancing the field of translational coeliac disease research as well as clinicians who are diagnosing and managing coeliac disease throughout all of its various stages.

  • Advanced Technologies in Electric Vehicles

    Challenges and Future Research Developments
    • 1st Edition
    • Vijayakumar Gali + 4 more
    • English
    Advanced Technologies in Electric Vehicles: Challenges and Future Research Developments discusses fundamental and advanced concepts, challenges, and future perspectives surrounding EVs. Sections cover advances and long-term challenges such as battery life span, efficiency, and power management systems. In addition, the book covers all aspects of the EV field, including vehicle performance, configuration, control strategy, design methodology, modeling and simulation for different conventional and modern vehicles based on mathematical equations. By tackling the fundamentals, theory and design of conventional electric vehicles (EVs), hybrid electric vehicles (HEVs), and fuel cell vehicles (FCVs), this book presents a comprehensive reference.Investment in hybrid and electric vehicle (EV) technology research has been increasing steadily in recent years, both from governments and within companies. The role of the combustion engine in causing climate change has put the automobile industry on a path of rapid evolution towards electric vehicles, bringing experts with a range of backgrounds into the field.

  • Transglutaminase

    Fundamentals and Applications
    • 1st Edition
    • Yi Zhang + 1 more
    • English
    Transglutaminase: Fundamentals and Applications, a new volume in the Foundations and Frontiers in Enzymology series, stands as a comprehensive resource on this increasingly important class of enzymes. Following an introduction to the field, international experts discuss basic biology and structure – function relationships of transglutaminases, ongoing fundamental research, and new application areas, including food processing, material synthesis, biomedicine, disease treatment, and biotechnology. Approaches for sourcing transglutaminases from animals, plants, and microorganisms are considered, followed by chapters on applied uses in biomedicine, skin, bone biology, medicine, drug development, tissue engineering, seafood bioprocessing, dairy bioprocessing, synthesis of materials and polymers, and as an immobilization agent.Research protocols are also provided, including research rationale, design, substrates, assays, and microassay steps for studying transglutaminases.

  • Control of Power Electronic Converters and Systems: Volume 4

    • 1st Edition
    • Frede Blaabjerg
    • English
    Control of Power Electronic Converters and Systems, Volume Four covers emerging topics in the control of power electronics and converters not covered in previous volumes, including emerging power converter topologies, storage systems, battery chargers and the smart transformer. This updated edition specifically focuses on emerging power converter topologies and discusses very recent advances and topics with applications in power electronics and formidable probable dynamics. Chapters include modeling of power converters and their control, with supportive simulations and additional experimental results.Anyone looking for fundamental knowledge regarding new trends in power electronics by application, and also ready to use models and methodologies in their design, control and testing will find this the next invaluable resource in this highly regarded series.

  • Nuclear Waste Management Facilities

    Advances, Environmental Impacts, and Future Prospects
    • 1st Edition
    • Rehab O Abdel Rahman
    • English
    Nuclear Waste Management Facilities examines best practices and recent trends in improving nuclear safety and reducing the negative environmental impacts of nuclear waste. With a strong emphasis on regulatory requirements, this reference is essential for designing new integrated waste management practices, using lessons learned from historical and current practices. Divided into three key parts, Part One introduces the reader to the safety and environmental impacts of the nuclear industry and the historical and current nuclear waste management practices. Part Two reviews recent technological and methodological approaches to enhancing safety, as well as reducing the environmental impacts of both individual processes and integrated facilities. Topics covered include spent fuel and radioactive waste management, legacy waste management, remediation, and decommissioning. Part Three considers some prospective for the safe management of waste from innovative reactors, and wastes that contain emerging contaminants, including waste recycling opportunities. Nuclear Waste Management Facilities is a crucial tool needed to implement the safest and most environmentally considerate best practices within nuclear waste management facilities.

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