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Academic Press

  • Translational Bioinformatics

    • 1st Edition
    • Volume 139
    • English
    Translational Bioinformatics is an emerging field in the direction of biomedical research. High throughput technologies can be applied to the generated biological data to develop the vaccine and personalized medicine. This volume consists of the chapters from different stalwart of the field covering the topics such as drug development, vector engineering, vaccine development and translational genomics. Chapters covered in this volume discuss the translational research related with cancer, Alzheimer disease and cardiovascular diseases. This volume includes the chapter describing the importance of computational resources and chemoinformatics for the translational health research. How Omics studies are helping to translate the laboratory data into the development of tools which are beneficial in the clinics have been described. How translational bioinformatics helpful in plant genomics to improve the crops have also been included in this volume. This volume has a chapter which describes the secrets of resistance development and further how these resistance are associated with human infectious diseases. This volume will be useful to the early career researcher in the development of research idea and develop their methodologies in the direction of bioinformatics and it will also give the insight to translate their findings.

  • RNA Therapeutics Part B

    • 1st Edition
    • Volume 204
    • English
    RNA Therapeutics, Part B, Volume 204 updates on a new class of medication based on RNA molecules, with chapters on a variety of topics, including RNA therapeutics for cardiovascular disorders, RNA therapeutics for kidney injury, RNA therapeutics for beta-thalassemia, RNA therapeutics for infectious diseases, RNA therapeutics for reproductive diseases, Potential of RNA and transcriptomic data to drive drug repurposing for various diseases, RNA therapeutics for glioma/glioblastoma, RNA therapeutics for regenerative medicine, Advances in the liposome-based delivery systems for RNA therapeutics in cancer, Advances in the polymeric nanoparticulate delivery systems for RNA therapeutics in cancer, and more.

  • Advances in Parasitology

    • 1st Edition
    • Volume 123
    • English
    Advances in Parasitology, Volume 123, the latest release in this ongoing series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy, and life history.

  • Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 4: Toxicologic Pathology of Organ Systems

    • 4th Edition
    • Wanda M. Haschek + 3 more
    • English
    Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume Four: Toxicologic Pathology of Organ Systems is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. Organ systems covered include cardiac, vascular and skeletal muscle systems and the endocrine, respiratory, reproductive, digestive and nervous systems. Completely revised with a new olfactory chapter, this new release is an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants.

  • Cell-based Cancer Immunotherapy

    • 1st Edition
    • Volume 183
    • English
    Cell-based Cancer Immunotherapy, Volume 183 provides the latest progress concerning research on anticancer cellular immunotherapies and their immunological, translation, or clinical aspects. Topics covered in this volume include Methods behind clinical DC vaccine products against glioblastoma, Fully closed and automated isolation of natural blood dendritic cells for cancer immunotherapy, Methods behind Oncolytic virus-based DC vaccines in cancer: towards a multiphase combined treatment strategy for Glioblastoma (GBM) patients, Identification of TCR repertoire patterns linked with anti-cancer immunotherapy, Training of epitope-TCR prediction models with healthy donor-derived cancer-specific T cells, Methods behind neoantigen predictions for anticancer vaccines, Methods behind CD137L-DC-EBV-VAX anticancer vaccine, and much more. Additional sections cover Gold Standard Assessment of Immunogenic Cell Death Induced by Photodynamic Therapy: From In Vitro to Tumor Mouse Models and Anti-Cancer Vaccination Strategies, Methods behind TCR analyses for colorectal cancer-associated TILs, The use of xCELLigence, Incucyte, and/or Cr/LDH/maker-release assays, Humanized mouse models for anti-cancer therapy, In vitro re-challenge of CAR T cells, Methods behind adoptively transferred tumor draining lymphocytes​ for anticancer immunotherapy, and A murine glioblastoma platform to test cellular therapies with the standard of care.

  • Advances in Experimental Social Psychology

    • 1st Edition
    • Volume 69
    • English
    The Advances in Experimental Social Psychology series is the premier outlet for reviews of mature, high-impact research programs in social psychology. Contributions to the series provide defining pieces of established research programs, reviewing and integrating thematically related findings by individual scholars or research groups. Topics discussed in Volume 69 include misinformation and inoculation, coherence of emotional response systems, environmental influences on behavior, human creativity, and social perception

  • The Lentil Genome

    Genetics, Genomics and Breeding
    • 1st Edition
    • Jitendra Kumar + 2 more
    • English
    The Lentil Genome: Genetics, Genomics and Breeding is a comprehensive volume on this important legume, from its economic importance to the latest in sequencing. The book includes botanical descriptions, discussion of lentil genetics, cytogenetics and breeding, molecular mapping genes and QTLs, as well as structural and functional genomics, genome sequencing, assembly, repetitive genome, gene annotation and synteny. Lentil [Lens culinaris ssp. culinaris Medikus] is among the earliest domesticates from the Near-East Fertile Crescent and plays a vital role in nutritional wellbeing and livelihood for the small-scale farmers in the dryland agricultural ecosystems of South Asia, Sub-Saharan Africa, West Asia, and North Africa. The classical plant breeding approach of selection-recombinat... has been used successfully for genetic improvement in lentil. However further genetic improvement for developing the high yielding cultivars is required knowledge of gene network underlying the complex traits. Realizing the importance of genomics enabled improvement in crop plants, the scientific community has recently placed major emphasis on whole genome sequencing in many major crops including lentil. This compilation of the latest lentil genome research serves the immediate needs of students, scientists and is needed to strengthen conventional crop improvement strategies of lentil.

  • Engineering Biology for Microbial Biosynthesis of Plant-Derived Bioactive Compounds

    • 1st Edition
    • Yongjun Wei + 2 more
    • English
    Engineering Biology for Microbial Biosynthesis of Plant-Derived Bioactive Compounds will be of great interest to undergraduate and graduate students, scientists, researchers, and engineers who work on the microbial production of plant-derived bioactive compounds. As many plant-derived bioactive compounds are the foundation of effective drugs to cure diseases, it's important to understand the limits of their applications in drugs and other industries. With the development of synthetic biology and green biomanufacturing, the biosynthesis of complex bioactive compounds is possible. However, the engineering fundamentals for microbial biosynthetic of plant-derived bioactive compounds is vast.This book summarizes the engineering fundamental biotechnologies for microbial production of plant-derived bioactive compounds, allowing the content to be easily accessed. Coverage includes summaries of key achievements, identification of challenges, current approaches, tips and tricks, and helpful insights into critical bottlenecks.

  • Secondary Metabolites and Biotherapeutics

    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Secondary Metabolites and Biotherapeutics presents the latest biotechnological advancements in the production of target secondary metabolites for medicinal use, including topics such as transcriptomics, nanotechnology, gene editing tools like CRISPR/CAS, secondary metabolites source and production.  Secondary metabolites derived from plants as a response to stress have always played a vital role in the pharmaceutical industry to produce medicines. However, their limited production in plants have always raised concerns for large-scale production. With the advancement of modern biotechnology, researchers around the globe are now able to engineer plants with specific chemical compositions.This book is a valuable resource to researchers in biotechnology, medical sciences, pharmaceutical biotechnology, pharmacology and plant biology.

  • Early Vascular Aging (EVA)

    New Directions in Cardiovascular Protection
    • 2nd Edition
    • Pedro Guimarães Cunha + 4 more
    • English
    Early Vascular Aging (EVA): New Directions in Cardiovascular Protection, Second Edition continues to be the most comprehensive and authoritative resource on premature alterations in artery structure and function. The book presents a novel approach to the problem of cardiovascular disease, showing it in relation to great vessels disease and revealing a comprehensive approach to the problem of increased rigidity of the great vessels, its causes, and further consequences. This second edition contains completely updated content with expanded coverage of basic and translational research, systematic reviews of the most prominent literature, discussion of applicability of new evidence and more. Written by an international team of clinicians and researchers, this is a valuable resource to basic and translational scientists, clinical researchers and clinicians in the cardiovascular field interested in prevention, diagnosis and treatment of EVA.

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