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Books in Life sciences

  • The Biology and Identification of the Coccidia (Apicomplexa) of Turtles of the World

    • 1st Edition
    • Donald W. Duszynski + 1 more
    • English
    The Biology and Identification of the Coccidia (Apicomplexa) of Turtles of the World is an invaluable resource for researchers in protozoology, coccidia, and parasitology, veterinary sciences, animal sciences, zoology, and biology. This first-of-its-kind work offers a taxonomic guide to apicomplexan parasites of turtles that enables easy parasite identification, with a summary of virtually everything known about the biology of each known parasite species. It is an important documentation of this specific area, useful to a broad base of readers, including researchers in biology, parasitology, animal husbandry, diseases of wild and domestic animals, veterinary medicine, and faculty members in universities with graduate programs in these areas. There are about 330 turtle species on Earth; many are endangered, a growing number of species are kept as pets, and some are still used as food by humans. Turtles, like other vertebrate animals have many different kinds of parasites (viruses, bacteria, protozoa, worms, arthropods, and others). Coccidiosis in turtles has prevented large-scale turtle breeding, and represents a serious problem in need of control. This succinct and highly focused book will aid in that effort.

  • Pathobiology of Human Disease

    A Dynamic Encyclopedia of Disease Mechanisms
    • 1st Edition
    • Linda M. McManus + 1 more
    • English
    Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human Organ Systems Molecular Pathology/Basic Mechanisms of Diseases Animal Models/Other Model Systems Experimental Pathology Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students.

  • Hormones

    • 3rd Edition
    • Anthony W. Norman + 1 more
    • English
    The 3rd edition of Hormones offers a comprehensive treatment of the hormones of humans all viewed from the context of current theories of their action in the framework of our current understanding their physiological actions as well as their molecular structures, and those of their receptors. This new edition of Hormones is intended to be used by advanced undergraduates and graduate students in the biological sciences. It will also provide useful background information for first year medical students as they engage in studies which are increasingly problem-based rather than discipline-focused. As the field of endocrinology itself has expanded so much in the past two decades, the up to date presentation of the basics presented in this book will be a solid foundation on which more specialized considerations can be based. New to this Edition: Hormones, 3rd Edition is organized with two introductory chapters followed by 15 chapters on selected topics of the molecular biology of the major endocrine systems operative in humans. Coverage, for the first time of the following hormones; ghrelin, oxyntomodulin, kisspeptin, adrenomedullin, FGF23, erythropoietin, VIP and extended coverage of NO. Coverage of the hypothalamus has been integrated with the anterior pituitary because of the intimate functional and relationship between the two. Consideration of the role of hormones in cancer has been integrated into the chapters on the relevant hormones. Each of these areas occupies a unique niche in our understanding of the biological world and is part of the universality of signaling systems and how they govern biological systems.

  • Current Laboratory Techniques in Rabies Diagnosis, Research and Prevention, Volume 1

    • 1st Edition
    • Charles Rupprecht + 1 more
    • English
    Laboratory Techniques in Rabies Diagnosis, Research and Prevention provides a basic understanding of the current trends in rabies. It establishes a new facility for rabies surveillance, vaccine and antibody manufacturing. It offers clarity about the choice of laboratory methods for diagnosis and virus typing, of systems for producing monoclonal and polyclonal antibodies and of methods for testing potency of vaccines and antibodies. The book covers advancements in the classical methods described as well as recent methods and approaches pertaining to rabies diagnosis and research.

  • Diet and Exercise in Cystic Fibrosis

    • 1st Edition
    • Ronald Ross Watson
    • English
    Diet and Exercise in Cystic Fibrosis, a unique reference edited by distinguished and internationally recognized nutritionist and immunologist Ronald Ross Watson, fills the gap in the current dietary modalities aimed at controlling cystic fibrosis. Using expert evaluation on the latest studies of the role of food and exercise in lifelong management of cystic fibrosis, this valuable resource shows how to maintain intestinal, hepatic, and pulmonary high quality function for improving quality of life for those with cystic fibrosis. A helpful tool for researchers and clinicians alike, this reference helps refine research targets, and provides the beginning of a structured dietary management scheme for those with cystic fibrosis.

  • Encyclopedia of Agriculture and Food Systems

    • 2nd Edition
    • Neal K. Van Alfen
    • English
    Encyclopedia of Agriculture and Food Systems, Second Edition, Five Volume Set addresses important issues by examining topics of global agriculture and food systems that are key to understanding the challenges we face. Questions it addresses include: Will we be able to produce enough food to meet the increasing dietary needs and wants of the additional two billion people expected to inhabit our planet by 2050? Will we be able to meet the need for so much more food while simultaneously reducing adverse environmental effects of today’s agriculture practices? Will we be able to produce the additional food using less land and water than we use now? These are among the most important challenges that face our planet in the coming decades. The broad themes of food systems and people, agriculture and the environment, the science of agriculture, agricultural products, and agricultural production systems are covered in more than 200 separate chapters of this work. The book provides information that serves as the foundation for discussion of the food and environment challenges of the world. An international group of highly respected authors addresses these issues from a global perspective and provides the background, references, and linkages for further exploration of each of topics of this comprehensive work.

  • Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

    Volume 4 - Mitophagy
    • 1st Edition
    • M. A. Hayat
    • English
    Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection and Aging, Volume 4 - Mitophagy presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson's Disease, cardiac aging, and skeletal muscle atrophy. The most current understanding of the proteins and pathways involved in mitophagy are covered, with specific attention to Nix and Bnip3, PINK1/Parkin, Atg32, and FUNDC1. The role of mitophagy in cancer, neurodegeneration, aging, infection, and inflammation is also discussed providing essential insights into the pathogenesis of a variety of mitochondria dysfunction-related diseases. This book is an asset to newcomers as a concise overview of the current knowledge on mitophagy, while serving as an excellent update reference for more experienced scientists working on other aspects of autophagy. From these well-developed foundations, researchers, translational scientists, and practitioners may work to better implement more effective therapies against some of the most devastating human diseases. Volumes in the Series Volume 1: Molecular Mechanisms. Elucidates autophagy’s association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer’s, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Volume 2: Role in General Diseases. Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases. Volume 3: Role in Specific Diseases. Explores the role of autophagy in specific diseases and developments, including: Crohn’s Disease, Gaucher Disease, Huntington’s Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis.Volume 4: Mitophagy. Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson Disease, cardiac aging, and skeletal muscle atrophy. Volume 5: Role in Human Diseases. Comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy’s effects in various cardiovascular, metabolic, and neurodegenerative disorders.Volume 6: Regulation of Autophagy and Selective Autophagy. Provides coverage of the mechanisms of regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity; and selective autophagy. Volume 7: Role of Autophagy in Therapeutic Applications. Provides coverage of the latest developments in autophagosome biogenesis and regulation; the role of autophagy in protein quality control; the role of autophagy in apoptosis; autophagy in the cardiovascular system; and the relationships between autophagy and lifestyle. Volume 8: Autophagy and Human Diseases. Reviews recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, and introduces new, more effective therapeutic strategies, in the development of targeted drugs and programmed cell death, providing information that will aid on preventing detrimental inflammation.Volume 9: Necrosis and Inflammation in Human Diseases. Emphasizes the role of Autophagy in necrosis and inflammation, explaining in detail the molecular mechanism(s) underlying the formation of autophagosomes, including the progression of Omegasomes to autophagosomes.

  • Marine Carbohydrates: Fundamentals and Applications, Part A

    • 1st Edition
    • Volume 72
    • English
    Marine Carbohydrates: Fundamentals and Applications brings together the diverse range of research in this important area which leads to clinical and industrialized products. The volume, number 72, focuses on marine carbohydrates in isolation, biological, and biomedical applications and provides the latest trends and developments on marine carbohydrates. Advances in Food and Nutrition Research recognizes the integral relationship between the food and nutritional sciences and brings together outstanding and comprehensive reviews that highlight this relationship. Volumes provide those in academia and industry with the latest information on emerging research in these constantly evolving sciences.

  • Electroporation-Based Therapies for Cancer

    From Basics to Clinical Applications
    • 1st Edition
    • Raji Sundararajan
    • English
    Electroporation-Base... Therapies for Cancer reviews electroporation-base... clinical studies in hospitals for various cancer treatments, including melanomas, head and neck cancers, chest wall breast carcinomas, and colorectal cancers, as well as research studies in the lab using cell lines, primary cells, and animals. Cancer kills about one American per minute, amounting to over 500,000 deaths in the United States and millions, worldwide, each year. There is a critical need for safe, effective, and affordable alternative treatment modalities, especially for inoperable, recurring, and chemo-resistant cancers, that do not respond well to current treatment regimen. An electrical-pulse-med... enhanced drug delivery technique known as electroporation is one way to effectively treat these patients. This technique is especially suitable for low- and middle-income countries, where lack of infrastructure and resources leads to cancer diagnoses at late stages. This quick, safe, effective, economical, out-patient-based technique is a boon to these patients for palliative and other care with enhanced quality of life. This book features discussions by interdisciplinary authors—including practicing oncological surgeons, medical professionals, and academic and other researchers—of the basics and clinical medical applications of electroporation.

  • Myopathies, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 32-3
    • Mazen Dimachkie
    • English
    Congential myopathies, Muscular dystropies, Glycogen storage diseases of muscle, and Idiopathic and Inflammatory myopathies are presented in this volume of Neurologic Clinics. Topics include: Muscle channelopathies; Pompe disease; Congenital myopathies and muscular dystrophies; Duchenne and Becker muscular dystrophies; Distal myopathies; Limb-girdle muscular dystrophy; Fascioscapulomuneral muscular dystrophy; Myotonic dystrophy; Metabolic and mitochondrial myopathies; Sporadic inclusion body myositis; Toxic myopathies; Idiopathic Inflammatory myopathies; Approach to muscle disease.

  • Hyaluronan Signaling and Turnover

    • 1st Edition
    • Volume 123
    • Melanie Simpson + 1 more
    • English
    Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. This volume covers hyaluronan signaling and turnover.

  • Mechanotransduction

    • 1st Edition
    • Volume 126
    • English
    Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references. Volume 126 features in-depth reviews that focus on the tools required to investigate mechanotransduction. Additional chapters focus on how we can use these tools to answer fundamental questions about the interaction of physical forces with cell biology, morphogenesis, and function of mature structures. Chapters in the volume are authored by a unique combination of cell biologists and engineers, providing a range of perspectives on mechanotransduction.

  • Regulated Cell Death Part B

    Necroptotic, Autophagic and other Non-apoptotic Mechanisms
    • 1st Edition
    • Volume 545
    • English
    Regulated Cell Death Part A & Part B of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches.

  • Molecular Genetics of Sex Determination

    • 1st Edition
    • Stephen S. Wachtel
    • English
    In this era of accelerated discovery and prolific output, Molecular Genetics of Sex Determination keeps readers abreast of this fields fast-moving biology. Its chapters were completed by experts in eacharea only months before publication. The text is organized into two parts. First, it reviews the basic biology of sex determination and summarizes ground-breaking work in mouse, marsupial, and Drosophila systems. Second, it covers current human genetics, clinical studies, and the syndromes of abnormal sex differentiation. With chapters by preeminent reproductive biologists, this is a capital work. Ohno's law is described by Ohno; the Lyon hypothesis, by Lyon; Sinclair tells how he cloned the testis-determining gene; and so on. Molecular Genetics of Sex Determination is authoritative, comprehensive, and current. It is prime reading for geneticists, developmental biologists, graduate students in these and related fields, clinical researchers, physicians, and medical students.

  • Aves

    • 1st Edition
    • Alan H. Brush
    • English

  • Modern Concepts of Focal Epileptic Networks

    • 1st Edition
    • Volume 114
    • English
    This volume of International Review of Neurobiology concentrates on modern concepts of focal epileptic networks. The volume addresses specific topics such as seizures (including transition and termination), limbic networks, alteration of metabolism, and neocortical focus and malformation of cortical development, among others. Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews, and thematic volumes that focus on recent progress in a specific area of neurobiology research.

  • Arthropoda Part B

    • 1st Edition
    • Marcel Florkin
    • English
    Chemical Zoology, Volume VI, Arthropoda Part B, provides zoologists and chemists with an overview of the state of knowledge in chemistry and zoology and an introduction to the existing literature. The treatise is arranged by phyla, an arrangement which seemed most suitable for presenting chemical information of zoological significance and for bringing to the attention of chemists those aspects of biochemical diversity of greatest potential interest. Each section, dealing with a major phylum, is introduced by a discussion of the biology and systematics of the group. This is followed by chapters dealing with various aspects of the biochemistry of the group. This volume contains 11 chapters that discuss the integument, hemolymph, blood respiratory pigments, hemolymph coagulation excretion, pigments, chemistry, toxicology, and pharmacology of Arthropoda. The respiration, energy metabolism, and chemical ecology of Crustacea as well as the oxidative metabolism of Insecta are also covered.

  • The Rhesus Monkey

    Volume II: Management, Reproduction, and Pathology
    • 2nd Edition
    • Geoffrey Bourne
    • English
    The Rhesus Monkey discusses the use of the rhesus monkey as a test subject in biomedical research. This text provides information that is essential for research that involves the rhesus monkey, from conditioning a wild rhesus monkey to restoring it to its natural state after the tests that it is subjected to. This book covers the phases a rhesus monkey specimen will go through in an experiment. Each chapter covers different facets of using a rhesus monkey as a test subject, including selecting a suitable specimen, conditioning, medication, nourishment, breeding, and pathological threats. Researchers in all fields will find this book an invaluable source of information regarding the best use of rhesus monkeys as research subjects.

  • The immune system

    • 1st Edition
    • Rodney Langman
    • English
    9780124365858 The Immune System: Evolutionary Principle Guide our Understanding of this Complex Biological Defense System provides the conceptual framework of immunology and the evolutionary events that have shaped the understanding of the immune system. This book contains 10 chapters, and begins with a brief discussion on the evolutionary aspects of immunology considering the Darwinian principles of evolution. This topic is followed by a presentation of the selective pressures that are likely to have molded the immune system, as well as the laws of the immune system and their corollaries concerning host defense mechanism. The subsequent chapters are devoted to cellular components of the immune system, including the B and T cells, immunoglobulins, interleukins, major histocompatibility complex, and lymphoid organs. The structural information and the evolutionary events in these immune system components are provided. A chapter focuses on the evolutionary successful components of the inflammatory system. The concluding chapter deals with the conflicting conventional wisdoms on functional immune system. This book will prove useful to immunologists and research workers in immunology and related fields.

  • Encyclopedia of Meat Sciences

    • 2nd Edition
    • Carrick Devine + 1 more
    • English
    The Encyclopedia of Meat Sciences, Second Edition, Three Volume Set prepared by an international team of experts, is a reference work that covers all important aspects of meat science from stable to table. Its topics range from muscle physiology, biochemistry (including post mortem biochemistry), and processing procedures to the processes of tenderization and flavor development, various processed meat products, animal production, microbiology and food safety, and carcass composition. It also considers animal welfare, animal genetics, genomics, consumer issues, ethnic meat products, nutrition, the history of each species, cooking procedures, human health and nutrition, and waste management. Fully up-to-date, this important reference work provides an invaluable source of information for both researchers and professional food scientists. It appeals to all those wanting a one-stop guide to the meat sciences.

  • Bone Substitute Biomaterials

    • 1st Edition
    • K. Mallick
    • English
    Bone substitute biomaterials are fundamental to the biomedical sector, and have recently benefitted from extensive research and technological advances aimed at minimizing failure rates and reducing the need for further surgery. This book reviews these developments, with a particular focus on the desirable properties for bone substitute materials and their potential to encourage bone repair and regeneration. Part I covers the principles of bone substitute biomaterials for medical applications. One chapter reviews the quantification of bone mechanics at the whole-bone, micro-scale, and non-scale levels, while others discuss biomineralization, osteoductivization, materials to fill bone defects, and bioresorbable materials. Part II focuses on biomaterials as scaffolds and implants, including multi-functional scaffolds, bioceramics, and titanium-based foams. Finally, Part III reviews further materials with the potential to encourage bone repair and regeneration, including cartilage grafts, chitosan, inorganic polymer composites, and marine organisms.

  • Textbook of Veterinary Physiological Chemistry

    • 3rd Edition
    • Larry Engelking
    • English
    Bridging the gap between basic and clinical science concepts, the Textbook of Veterinary Physiological Chemistry, Third Edition offers broad coverage of biochemical principles for students and practitioners of veterinary medicine. The only recent biochemistry book written specifically for the veterinary field, this text covers cellular-level concepts related to whole-body physiologic processes in a reader-friendly, approachable manner. Each chapter is written in a succinct and concise style that includes an overview summary section, numerous illustrations for best comprehension of the subject matter, targeted learning objectives, and end of the chapter study questions to assess understanding. With new illustrations and an instructor website with updated PowerPoint images, the Textbook of Veterinary Physiological Chemistry, Third Edition, proves useful to students and lecturers from diverse educational backgrounds. Sectional exams and case studies, new to this edition, extend the breadth and depth of learning resources.

  • Cognition, Intelligence, and Achievement

    A Tribute to J. P. Das
    • 1st Edition
    • Timothy Papadopoulos + 2 more
    • English
    Cognition, Intelligence, and Achievement is motivated by the work of the renowned Professor J. P. Das on the PASS (Planning, Attention, Simultaneous and Successive Processing) theory of intelligence and CAS measures (Cognitive Assessment System) of cognitive processes. This book reviews current research using this and other frameworks in understanding the relationships among cognition, intelligence, and achievement. The assessment and diagnosis of learning disabilities, mental retardation, and ADHD are addressed, and the interrelationships among cognition, culture, neuropsychology, academic achievement, instruction, and remediation are examined. No other book has presented such an integrated view across these domains, from such a diverse array of internationally known and respected experts from psychology, education, and neuroscience.

  • Colloid and Interface Science in Pharmaceutical Research and Development

    • 1st Edition
    • Hiroyuki Ohshima + 1 more
    • English
    Colloid and Interface Science in Pharmaceutical Research and Development describes the role of colloid and surface chemistry in the pharmaceutical sciences. It gives a detailed account of colloid theory, and explains physicochemical properties of the colloidal-pharmaceut... systems, and the methods for their measurement. The book starts with fundamentals in Part I, covering fundamental aspects of colloid and interface sciences as applied to pharmaceutical sciences and thus should be suitable for teaching. Parts II and III treat applications and measurements, and they explains the application of these properties and their influence and use for the development of new drugs.

  • Cytogenetics of Cells in Culture

    • 1st Edition
    • R. J. C. Harris
    • English
    Cytogenetics of Cells in Culture is a compendium of papers that deals with techniques to detect patterns of DNA replication, cellular control mechanisms, and chromosome analyses with automated instrumentation. Some papers discuss the effects of cell hybridization and of noxious substances such as radiation, chemical agents, and viruses on chromosomal patterns. Other papers focus on the influence of altered chromosomal complement on the survival of cells to long-term tissue culture or to ionizing radiation treatment. A couple of papers points out that naturally occurring chromosomal abnormalities in mammalian populations are relatively rare and are not necessarily associated with physical defects or disease. One paper notes that chromosomes in cells with different functions have different patterns of replication in which the changes are small and hidden. The chromosomes will usually be neutralized showing little of the characteristic pattern of replication or condensation during the early cleavage stages, that will later change into differentiated characteristic ways for each tissue type. Another paper describes chromosome breakage associated with viruses and DNA inhibitors. The compendium can prove beneficial for biochemists, micro-biologists, cellular researchers, and academicians involved in the study of cellular biology or physiology.

  • Neurobiology of Social Behavior

    Toward an Understanding of the Prosocial and Antisocial Brain
    • 1st Edition
    • Michael Numan
    • English
    Social neuroscience is a rapidly growing, interdisciplinary field which is devoted to understanding how social behavior is regulated by the brain, and how such behaviors in turn influence brain and biology. Existing volumes either fail to take a neurobiological approach or focus on one particular type of behavior, so the field is ripe for a comprehensive reference which draws cross-behavioral conclusions. This authored work will serve as the market’s most comprehensive reference on the neurobiology of social behavior. The volume will offer an introduction to neural systems and genetics/epigenetics... followed by detailed study of a wide range of behaviors – aggression, sex and sexual differentiation, mating, parenting, social attachments, monogamy, empathy, cooperation, and altruism. Research findings on the neural basis of social behavior will be integrated across different levels of analysis, from molecular neurobiology to neural systems/behavioral neuroscience to fMRI imaging data on human social behavior. Chapters will cover research on both normal and abnormal behaviors, as well as developmental aspects.

  • Lockhart and Wiseman’s Crop Husbandry Including Grassland

    • 9th Edition
    • Steve Finch + 2 more
    • English
    Increased yields, markets, and profitability have led to changes in crop husbandry. Since its first publication in 1966, revised editions of Lockhart & Wiseman's Crop Husbandry Including Grassland have upheld and increased the book's good reputation. This ninth edition maintains its status as the standard textbook for many agricultural courses. Part one covers the principles of crop production with chapters concerning plants, climate, soil management, fertilizers, manures, weeds, and diseases threatening farm crops. Part two surveys crop husbandry techniques. Environmental impact has been addressed in greater detail in this edition. This section looks at issues such as sustainable crop management, precision farming, and organic crop husbandry. The way these general techniques apply to individual crops is explained in part three. This part considers a range of cereals, combinable break crops, root crops, industrial crops, and fresh produce crops. Part four looks at the use of grassland and forage crops, with chapters considering arable forage crops, the characteristics of grassland, and the corresponding methods for establishing and improving grassland. This part also includes information regarding equine grassland management and conservation of grass and forage crops. This ninth edition of Lockhart and Wiseman's Crop Husbandry Including Grassland is relevant for students throughout the United Kingdom and Europe. It is a useful reference book for agriculture National Diploma courses, Foundation Degrees, and BSc degrees, and is important for Masters level students entering agriculture from another discipline.

  • Advances in Planar Lipid Bilayers and Liposomes

    • 1st Edition
    • Volume 20
    • English
    Although the origin and the basic meaning of the terms "planar lipid bilayers" and "liposome" have not changed during the years, the present advances in the scientific, technological, biomedical and consumer product fields are remarkable. Ever since its launch the "Advances in Planar Lipid Bilayers and Liposomes’ (APLBL) has provided a global platform for a community of researchers having very broad scientific interests in theoretical, experimental and simulation studies on lipid and cell membrane micro and nanostructures. Ranging from artificial lipid membranes to cell membranes, controlled release of functional molecules, drug delivery to cancer cells, pharmaceutical formulations to food products, the applications are simply enormous. An assortment of chapters in APLBL represents both an original research as well as comprehensives reviews written by world leading experts and young researchers.

  • The Interpretation of Ultrastructure

    • 1st Edition
    • R. J. C. Harris
    • English
    The Interpretation of Ulstrastructure is a collection of papers dealing with techniques in ulstrastructural research such as in fixation, reversed staining, ultrastructure in embryos and in plants, control of observations by light microscopy, and cytochemistry at the electron microscope level. One paper describes various fixatives used on rat liver tissue including a standard osmium tetroxide solution, pure melted osmium tetroxide, and strong osmium tetroxide solutions in carbon tetrachloride. Another paper points out that the use of electron micrographs of the cell nucleus and chromosomes should include approaches to chromosome analysis. For the investigator studying the three dimensional organization of chromosomes, his approaches should include classical cytology and cytogenetics, chemical and cytochemical studies on nuclei, as well as chemical and physical analysis of nucleic acid and nucleoprotein molecules. Several papers discuss the study of natural and artificial DNA-plasma by thin sections, an assessment of negative staining techniques for revealing ultrastructure, and other approaches in the study of biological ultrastructure by high-resolution electron microscopy. The collection will benefit microbiologists, biotechnologists, and academicians connected with the biological sciences.

  • Cell Growth and Cell Division

    • 1st Edition
    • R. J. C. Harris
    • English
    Cell Growth and Cell Division is a collection of papers dealing with the biochemical and cytological aspects of cell development and changes in bacterial, plant, and animal systems. One paper discusses studies on the nuclear and cytoplasmic growth of ten different strains of the genus Blepharisma, in which different types of nutrition at high and low temperatures alter the species to the extent that they became morphologically indistinguishable. The paper describes the onset of death at high and low temperatures as being preceded by a decrease in the size of the cytoplasm and a corresponding decrease in the size of the macronucleus. The moribund organisms, still possessing structure, are motionless with no distinguishable macronuclear materials. Another paper presents the response of meiotic and mitotic cells to azaguanine, chloramphenicol, ethionine, and 5-methyltryptophan. The paper describes the failure of spindle action, arrest of second division, inhibition of cytokinesis, aberrant wall synthesis, and alterations in chromosome morphology in meiosis cells. In the case of mitosis, a single enzyme—thymidine phosphorylase—shows that reagents which inhibit protein synthesis also inhibit the appearance of that enzyme if the reagent is applied one day before it normally appears. Other papers discuss control mechanisms for chromosome reproduction in the cell cycle, as well as the force of cleavage of the dividing sea urchin egg. The collection can prove valuable for bio-chemists, cellular biologists, micro-biologists, and developmental biologists.

  • Carbohydrate Metabolism

    Comprehensive Biochemistry
    • 1st Edition
    • Volume 17
    • Marcel Florkin + 1 more
    • English
    Comprehensive Biochemistry, Volume 17: Carbohydrate Metabolism focuses on the processes, reactions, and transformations involved in the metabolism of carbohydrates, including glycosaminoglycans, enzymes, oxidation, and glycolysis. The selection first elaborates on functional organization contributing to carbohydrate economy and control of synthesis and breakdown of glycogen, starch, and cellulose. Discussions focus on breakdown of glycogen in mammalian systems, role of glycogen in the regulation of glycogen metabolism, glycogen and starch metabolism in bacteria and plants, carbohydrate digestion, and integration of digestion and absorption. The book also ponders on regulation and mechanisms of enzymes and hexose-monophosphate oxidation, including functions and regulation of pentose-phosphate cycle glucose transport and role of subsequent steps in regulating the rate of glycolysis. The book takes a look at the metabolism of glycosaminoglycans, aldonic and uronic acids, and carbohydrate and oxidative metabolism in neural systems. Concerns include control of carbohydrate metabolism, adaptive changes in relation to carbohydrate metabolism, uronic and aldonic acid metabolism in plants and microorganisms, and mechanism of alternation of monosaccharide units. The selection is a vital source of data for researchers interested in carbohydrate metabolism.

  • Protides of the Biological Fluids

    Proceedings of the Seventeenth Colloquium, Bruges, 1969
    • 1st Edition
    • H. Peeters
    • English
    Protides of the Biological Fluids documents the proceedings of the XVIITH Colloquium held in Bruges in 1969. This book is divided into three sections. Section A discusses the genetics of the antibody response, focusing on the evolutionary aspects and genetics of differentiation centered on the problems of immunoglobulin structure and deficiencies. The molecular variation occurring in the amino acid sequence of various proteins, its ways of detection and its physiological significance, is presented in Section B. Some of the proteins considered include hemoglobin, fibrinogen, complement, and lipoproteins. Section C is devoted to the developments in theoretical and instrumental aspects of electrofocusing, considering the ampholyte structure and function and techniques, such as gel electrofocusing and preparative column electrofocusing. This compilation is beneficial to researchers and specialists concerned with protides of the biological fluids.

  • Differentiation and Immunology

    Symposia of the International Society for Cell Biology, Vol. 7
    • 1st Edition
    • Katherine Brehme Warren
    • English
    Differentiation and Immunology is a collection of papers that deals with molecular specificity—the link between immunology and differentiation. One paper reviews the status of regulation in bacteria or viruses, and extends the results to animal cells. The paper also investigates a single aspect of the control of immunoglobulin through the use of plasmacytomas. Another paper discusses the role of macrophages in the minimum theory to possibly account for the energetics of the reaction with receptors, or to the frequency of antigen-sensitive cells. Some papers investigate the immunogenic function of macrophages, the transition from monocyte to macrophage, the factors influencing the formation of macrophage lysosomes, and the origin of macrophage lysosomes. Other papers also discuss the immune response as a model system for studies on cellular differentiation, as well as the differentiation for collagen synthesis in cultured cells. One paper suggests that in differentiation, the changes that can occur in the properties of protozoan cells, perpetuated for long periods, are reversible, and can be a means for survival—as every cell line is also capable of being a germ line. This collection can prove valuable to bio-chemists, cellular biologists, micro-biologists, developmental biologists, and scientists involved in immunology research.

  • Drugs, Addiction, and the Brain

    • 1st Edition
    • George F. Koob + 2 more
    • English
    Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain.

  • Neurovirology

    • 1st Edition
    • Volume 123
    • Alex C. Tselis + 1 more
    • English
    This volume in the Handbook of Clinical Neurology series provides a complete review of the history, science and current state of neurovirology. It covers the science and clinical presentation, diagnosis, and treatment of viruses of the brain and central nervous system, and is a trusted resource for scholars, scientists, neuroscientists, neurologists, virologists, and pharmacologists working on neurovirology. Neurovirology has been significantly bolstered by modern technologies such as PCR and MRI with direct impact on isolating viruses and advancing therapeutics based on molecular medicine. These advances are particularly important today with the introduction of emerging and re-emerging diseases such as HIV/AIDS, Nipah encephalitis and the appearance of West Nile encephalitis in the western hemisphere.

  • Natural Hosts of SIV

    Implication in AIDS
    • 1st Edition
    • Aftab A. Ansari + 1 more
    • English
    Natural Hosts of SIV: Implications in AIDS thoroughly reviews the possible mechanisms by which African nonhuman primate natural hosts of lentiviruses remain essentially disease-free while other hosts exhibit disease and death. The book ultimately indicates directions for further research and potential translations of this compelling phenomenon into novel approaches to treat and prevent HIV. When Asian non-human primate non-natural hosts are experimentally infected with viruses isolated from African species, disease and death normally results. Meanwhile, these African nonhuman primate natural hosts maintain similar levels of plasma and cellular viremia and exhibit compellingly different, essentially disease-free, states. This work attempts to answer the question of how the natural host remains disease resistant.

  • Alkyl Polyglucosides

    From Natural-origin Surfactants to Prospective Delivery Systems
    • 1st Edition
    • Ivana Pantelic
    • English
    The on-going ‘green’ trend in the personal care industry coupled with global environmental concerns, place natural-origin, biodegradable and skin-friendly surfactants such as alkyl polyglucosides (APGs) in high demand. After successful use in cosmetics, sufficient data has been obtained to welcome some sugar emulsifiers into the field of drug dosage. Alkyl Polyglucosides presents a comprehensive compendium which guides a researcher from the APG-related preformulation stages to formulation processing, including the investigation of various APG-stabilized systems skin performance. This book introduces various APG representatives, their benefits in relation to certain conventional surfactants, physicochemical and interfacial properties, possible interaction with commonly used ingredients and diverse characterization techniques indispensable for the assessment of colloidal systems. The first chapter introduces alkyl polyglucosides, followed by chapters on their properties, behaviour, an overview of the patent protection mechanisms and guidelines for submitting patent applications. Finally, a conclusion surveys international patent applications involving APGs.

  • Milk Proteins

    From Expression to Food
    • 2nd Edition
    • Mike Boland + 2 more
    • English
    Understanding of the interactions of milk proteins in complex food systems continues to progress, resulting in specialized milk-protein based applications in functional foods, and in protein ingredients for specific health applications. Milk Proteins is the first and only presentation of the entire dairy food chain – from the source to the nutritional aspects affecting the consumer. With focus on the molecular structures and interactions of milk proteins in various processing methods, Milk Proteins presents a comprehensive overview of the biology and chemistry of milk, as well as featuring the latest science and developments. Significant insight into the use of milk proteins from an industry viewpoint provides valuable application-based information. Those working with food and nutritional research and product development will find this book useful.

  • An Introduction to Aquatic Toxicology

    • 1st Edition
    • Mikko Nikinmaa
    • English
    An Introduction to Aquatic Toxicology is an introductory reference for all aspects of toxicology pertaining to aquatic environments. As water sources diminish, the need to understand the effects that contaminants may have on aquatic organisms and ecosystems increases in importance. This book will provide you with a solid understanding of aquatic toxicology, its past, its cutting-edge present and its likely future. An Introduction to Aquatic Toxicology will introduce you to the global issue of aquatic contamination, detailing the major sources of contamination, from where they originate, and their effects on aquatic organisms and their environment. State-of-the-art toxicological topics covered include nanotoxicology, toxicogenomics, bioinformatics, transcriptomics, metabolomics, as well as water management and the toxicological effects of major environmental issues such as algal blooms, climate change and ocean acidification. This book is intended for anyone who wants to know more about the impact of toxicants on aquatic organisms and ecosystems, or to keep up to date with recent and future developments in the field.

  • The Rat Nervous System

    • 4th Edition
    • George Paxinos
    • English
    The previous editions of The Rat Nervous System were indispensable guides for those working on the rat and mouse as experimental models. The fourth edition enhances this tradition, providing the latest information in the very active field of research on the brain, spinal cord, and peripheral nervous system. The structure, connections, and function are explained in exquisite detail, making this an essential book for any graduate student or scientist working on the rat or mouse nervous system.

  • The Polysaccharides

    • 1st Edition
    • Gerald O. Aspinall
    • English
    The Polysaccharides, Volume 2 is a seven-chapter text that presents the status of polysaccharide chemistry and related aspects of biochemistry. The opening chapter is concerned with the major classifications of polysaccharides, such as homoglycans and diheteroglycans. The succeeding five chapters discuss the occurrence, usage, structural studies, conformation, and derivatives of specific carbohydrate group, including cellulose, plant, algal, bacterial, and fungal polysaccharides. The last chapter deals with the industrial application and economic aspects of polysaccharides. This book will prove useful to chemists and biochemists working on polysaccharides and other complex carbohydrates.

  • Microencapsulation in the Food Industry

    A Practical Implementation Guide
    • 1st Edition
    • Robert Sobel
    • English
    Microencapsulation is being used to deliver everything from improved nutrition to unique consumer sensory experiences. It’s rapidly becoming one of the most important opportunities for expanding brand potential. Microencapsulation in the Food Industry: A Practical Implementation Guide is written for those who see the potential benefit of using microencapsulation but need practical insight into using the technology. With coverage of the process technologies, materials, testing, regulatory and even economic insights, this book presents the key considerations for putting microencapsulation to work. Application examples as well as online access to published and issued patents provide information on freedom to operate, building an intellectual property portfolio, and leveraging ability into potential in licensing patents to create produce pipeline.This book bridges the gap between fundamental research and application by combining the knowledge of new and novel processing techniques, materials and selection, regulatory concerns, testing and evaluation of materials, and application-specific uses of microencapsulation.

  • Sturkie's Avian Physiology

    • 6th Edition
    • Colin G. Scanes
    • English
    Sturkie's Avian Physiology is the classic comprehensive single volume on the physiology of domestic as well as wild birds. The Sixth Edition is thoroughly revised and updated, and features several new chapters with entirely new content on such topics as migration, genomics and epigenetics. Chapters throughout have been greatly expanded due to the many recent advances in the field. The text also covers the physiology of flight, reproduction in both male and female birds, and the immunophysiology of birds. The Sixth Edition, like the earlier editions, is a must for anyone interested in comparative physiology, poultry science, veterinary medicine, and related fields. This volume establishes the standard for those who need the latest and best information on the physiology of birds.

  • The Biological Clock

    Two Views
    • 1st Edition
    • Frank A. Brown + 2 more
    • English
    The Biological Clock describes the rhythmic processes in a great variety of plants and animals. This book is an outgrowth of the 1969 James Arthur Lecture Series on "Time and its Mysteries" held at New York University. This three-chapter work begins with the basic principles of biological rhythms and clocks, along with various diagrams to illustrate some aspects of circadian rhythms in animals. The second chapter discusses the hypothesis of environmental timing of the clock. This chapter explores numerous research studies on phenomenon of biological rhythms, the nature of the rhythmic mechanism, and hormonal regulation. The third chapter examines the cellular-biochemical clock hypothesis and its contribution in the progress of understanding the complexity of biological rhythm. This book is intended primarily for biologists, behaviorists, and researchers.

  • Bioenergetics 2

    • 1st Edition
    • David G. Nicholls + 1 more
    • English
    Bioenergetics 2 aims to clarify topics such as the thermodynamics of bioenergetic processes and the stoichiometries of energy coupling reactions. The book discusses chemiosmotic energy transduction; ion transport across energy-conserving membranes; and quantitative bioenergenetics as the measurement of driving forces. The text also describes the chemiosmotic proton circuit; the respiratory chain; the photosynthetic generators of protonmotive force; and the ATP synthase. The secondary transport of products across the membrane, as well as the structures of the bacterial photosynthetic reaction center and bacteriorhodopsin are also considered. Biochemists will find the book invaluable.

  • Immunointervention in Autoimmune Diseases

    Papers Based on an International Meeting in Paris, France, in June 1988
    • 1st Edition
    • J. F. Bach
    • English
    Immunointervention in Autoimmune Diseases is a collection of papers presented at the 1988 International Meeting by the same title, held in Paris, France. This text contains 21 chapters and begins with surveys of the role of antigen in autoimmune responses and the moving boundaries between physiology and pathology of immunity. The succeeding chapters deal with the regulation, immunosuppressive therapy, infections, and immunointervention of autoimmune disorders. These topics are followed by discussions of specific immunosuppressive therapy for a particular disease, including type I diabetes, T-cell leukemia, and systemic lupus erythomatosus. This work also explores the principles of allograft, the use of monoclonal antibody, and OKT3. The remaining chapters consider the maintenance of autoimmunity and the risk/benefit in immunointervention for autoimmune diseases. This book will prove useful to immunologists, pathologists, physiologists, and researchers.

  • Handbook of Immunological Investigations in Children

    Handbooks of Investigation in Children
    • 1st Edition
    • J. Graham Watson + 1 more
    • English
    Handbook of Immunological Investigations in Children presents an extensive examination of the immune system of children. It discusses the fundamental concepts in immunology. It addresses studies in the primary immunodeficiency diseases. Some of the topics covered in the book are the respiratory disorders; renal disorders; gastrointestinal disorders; endocrine disorders; neurological and psychiatric disease; identifications of diseases of the skin; muscle malfunction and connective tissue disorder; and the methods of infections and immunizations. The definition and description of factors influencing blood and blood-forming elements are fully covered. An in-depth account of the factors causing allergies and cardiovascular diseases are provided. The general characteristics of severe combined immunodeficiency are completely presented. A chapter is devoted to usage of immunoglobulin therapy. Another section focuses on the disorders of neutrophils, monocytes, and macrophages. The book can provide useful information to immunologists, pediatricians, doctors, students, and researchers.

  • Microbiology in Clinical Practice

    • 2nd Edition
    • D. C. Shanson
    • English
    Microbiology in Clinical Practice presents the infections and syndromes caused by micro-organisms. It discusses the management of infective diseases and aetiological agents. It addresses the latex agglutination, immunofluorescent, monoclonal antibody, and nucleic acid probe investigations. Some of the topics covered in the book are the classification and pathogenicity of microbes; classification of bacteria; classification of viruses; classification of fungi; general principles of antimicrobial chemotherapy; antibiotic sensitivity tests; procedures in the laboratory for microbiological diagnosis; and the mode of action of antimicrobial drugs. The resistance to antimicrobial drugs are covered. The microbiological investigations of septicaemia are discussed. The text describes the human immunodeficiency virus infection and AIDS in infants. A study of the congenital immunodeficiency and impaired resistance to infection is presented. A chapter is devoted to the predisposing factors for anaerobic infections. Another section focuses on the infections of the central nervous system. The book can provide useful information to doctors, pathologists, neurologists, students, and researchers.

  • The Third World Congress on Biosensors Abstracts

    1-3 June 1994, New Orleans, USA
    • 1st Edition
    • Abstracts
    • English
    Biosensors 94: The Third World Congress on Biosensors Abstracts focuses on the progress in the field of biosensors, including immuno-absorbent 'catch' system, surface plasmon resonance, and chemiluminescence. The selection first offers information on the development of a commercial multichannel clinical sensor chip; commercial development and application of biosensors; amperometric biosensors based on dehydrogenase/NAD and heterocyclic quinones; and enzyme-epoxy membrane based semi-automated glucose analyzing system. The text then takes a look at the orientation of antibody fragments to increase TIRF immunosensor efficiency and the development of latex-technology for specific DNA detection with surface plasmon resonance. The book elaborates on gas-phase biosensor for the determination of ethanol vapor; novel electrochemical gas phase biosensors for the detection of phenolic vapors; and the development of an immuno-absorbent 'catch' system for the detection of pesticides and pesticide analogues. The book also ponders on the kinetics of binding of immobilized antibodies under nonequilibrium, flow conditions; flow injection thin-layer cell immunosensor with chemiluminescent detection of peroxidase label; and new optical fiber sensor for detecting chemiluminescence and its application to immunoassay. The selection is a valuable source of data for researchers interested in biosensors.

  • Raw Materials Purchasing

    An Operational Research Approach
    • 1st Edition
    • Volume 4
    • B. G. Kingsman
    • English
    A systematic study of commodity purchasing analysed from an operational research viewpoint and based on numerous case studies.

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