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Books in Life sciences

  • Understanding Climate Change Impacts on Crop Productivity and Water Balance

    • 1st Edition
    • S. K. Jalota + 3 more
    • English
    Understanding Climate Change Impacts on Crop Productivity and Water examines the greenhouse gas emissions and their warming effect, climate change projections, crop productivity and water. The book explores the most important greenhouse gases that influence the climate system, technical terms associated with climate projections, and the different mechanisms impacting crop productivity and water balance. Adaptive and mitigative strategies are proposed to cope with negative effects of climate change in particular domains. This book will help researchers interested in climate change impacts on the atmosphere, soil and plants.
  • The Microbiology of Central Nervous System Infections

    • 1st Edition
    • Volume 3
    • English
    The Microbiology of Central Nervous System Infections, Volume 3, discusses modern approaches to the diagnosis, treatment and prophylaxis of central nervous system (CNS) infections. This new release is divided into five sections that cover treatment strategies, imaging, molecular diagnosis, management of CNS infections with metal nanoparticles, and prophylaxis of CNS infections, including bacterial, viral and fungal infections. The last section contains a chapter on transmissible spongiform encephalopathies and modern trends in its diagnosis and treatment. University teachers, medical practitioners, graduate and postgraduate students, researchers in microbiology, and those in the pharmaceutical and laboratory diagnostic industries will find the book very important.
  • Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination

    • 1st Edition
    • Volume 600
    • English
    Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination, Volume 600, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Homologous genetic recombination remains the most enigmatic process in DNA metabolism. The molecular machines of recombination preserve the integrity of the genetic material in all organisms and generate genetic diversity in evolution. The same molecular machines that support genetic integrity by orchestrating accurate repair of the most deleterious DNA lesions, however, also promote survival of cancerous cells and emergence of radiation and chemotherapy resistance. This two-volume set offers a comprehensive set of cutting edge methods to study various aspects of homologous recombination and cellular processes that utilize the enzymatic machinery of recombination The chapters are written by the leading researches and cover a broad range of topics from the basic molecular mechanisms of recombinational proteins and enzymes to emerging cellular techniques and drug discovery efforts.
  • Protein-Protein Interactions in Human Disease, Part B

    • 1st Edition
    • Volume 111
    • English
    Protein-Protein Interactions in Human Disease, Volume 111, Part B, promotes further research and development in the protein interaction network in order to identify critical proteins involved in the etiology of human diseases and locate new protein targets for drug development. Thus, this volume is of considerable interest to protein chemists, pharmacologists, cell biologists, immunologists, structural biologists, computational biochemists and other researchers working in the field. In addition, these articles would be of great benefit to medical, biology and pharmacology students who specialize in this field.
  • Systems Biology and Its Application in TCM Formulas Research

    • 1st Edition
    • Weidong Zhang
    • English
    Systems Biology and Its Application in TCM Formulas Research presents a theoretical research system formed for Traditional Chinese Medicine (TCM) formulas, along with information on the study of Shexiang Baoxin Pill (SBP), a TCM formula that has shown significant clinical efficacy in the treatment of cardiovascular diseases. The content combines theory and practice, and includes guidance for both theoretical concepts and operable technical routes. This is a valuable source not only for biomedical researchers involved in Systems Biology studies, but also for students and scientists interested in learning more about Traditional Chinese Medicine and its applications in contemporary medicine.
  • Precision Medicine

    Tools and Quantitative Approaches
    • 1st Edition
    • Hans-Peter Deigner + 1 more
    • English
    Precision Medicine: Tools and Quantitative Approaches discusses precision and personalized medicine, two relevant topics that are revolutionizing diagnostics and treatment, while also providing a shift toward prevention. The book covers the most relevant features and explanations underlying developments in the field. A timely review on prerequisites, causes and consequences is given. Unique to this book is a combined view on technical and data analysis aspects that is mandatory for obtaining and interpreting results. This book is a valuable source for researchers in medical and life sciences, physicians and students with an interest in this emerging field of precision medicine.
  • Advances in Immunology

    • 1st Edition
    • Volume 137
    • English
    Advances in Immunology, Volume 137, the latest in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release including sections on Notch and T-Cell signaling/T-Cell memory, Single Cell Analysis of CD8+ and CD4+ T Cell Differentiation, New Developments in the Chemokine Field, the Role of Caveolin-1 in BCR and TCR Receptors, The Unusual Biochemistry of Bovine Immunoglobulins, and the Molecular Aspects of Allergens and Allergy.
  • A Comprehensive Guide to the Prostate

    Eastern and Western Approaches for Management of BPH
    • 1st Edition
    • Bilal Chughtai
    • English
    A Comprehensive Guide to the Prostate: Eastern and Western Approaches for Management of BPH provides a multidisciplinary approach to BPH and male voiding dysfunction, presenting comprehensive guidance on management. With an equal focus on traditional, complementary and alternative medicine, and a look at novel technologies, a complete understanding of the BPH disease process is revealed. Abstracts and references in every chapter make the connection between research and practice. Perfect for researchers and urologists, this must-have reference provides what is needed to understand BPH and male voiding dysfunction.
  • Advances in Agronomy

    • 1st Edition
    • Volume 148
    • English
    Advances in Agronomy continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.
  • Transgenic Plants and Beyond

    • 1st Edition
    • Volume 86
    • English
    Transgenic Plants, Volume 86, the latest release in the series Advances in Botanical Research, brings together information needed by many teachers, researchers and managers who have to consider biotechnology from a scientific or legal point-of-view. It presents authors who bring their long personal experience on a given subject. Although the subjects are technical in nature, the take-home message of each chapter is understandable by non-specialists.
  • Food Control and Biosecurity

    • 1st Edition
    • Volume 16
    • Alexandru Mihai Grumezescu + 1 more
    • English
    Food Control and Biosecurity, Volume Sixteen, the latest release in the Handbook of Food Bioengineering series, is an essential resource for anyone in the food industry who needs to understand safety and quality control to prevent or reduce the spread of foodborne diseases. The book covers information from exporter to transporter, importer and retailer, and offers valuable tools to measure food quality while also addressing government standards and regulations for food production, processing and consumption. The book presents cutting-edge methods for detecting hazardous compounds within foods, including carcinogenic chemicals. Other related topics addressing food insecurity and food defense are also discussed.
  • ODE/PDE α-synuclein Models for Parkinson’s Disease

    • 1st Edition
    • William E. Schiesser
    • English
    ODE/PDE Alpha-Synuclein Models for Parkinson’s Disease discusses a mechanism for the evolution of Parkinson’s Disease (PD) based on the dynamics of the protein α-synuclein, a monomer that has been implicated in this disease. Specifically, α-synuclein morphs and aggregates into a polymer that can interfere with functioning neurons and lead to neurodegenerative pathology. This book first demonstrates computer-based implementation of a prototype ODE/PDE model for the dynamics of the α-synuclein monomer and polymer, and then details the methodology for the numerical integration of ODE/PDE systems which can be applied to computer-based analyses of alternative models based on the reader's interest. This book facilitates immediate computer use for research without the necessity to first learn the basic concepts of numerical analysis for ODE/PDEs and programming algorithms
  • Food Process Engineering and Technology

    • 3rd Edition
    • Zeki Berk
    • English
    Food Process Engineering and Technology, Third Edition combines scientific depth with practical usefulness, creating a tool for graduate students and practicing food engineers, technologists and researchers looking for the latest information on transformation and preservation processes and process control and plant hygiene topics. This fully updated edition provides recent research and developments in the area, features sections on elements of food plant design, an introductory section on the elements of classical fluid mechanics, a section on non-thermal processes, and recent technologies, such as freeze concentration, osmotic dehydration, and active packaging that are discussed in detail.
  • Forensic Ecogenomics

    The Application of Microbial Ecology Analyses in Forensic Contexts
    • 1st Edition
    • T. Komang Ralebitso-Senior
    • English
    Forensic Ecogenomics: The Application of Microbial Ecology Analyses in Forensic Contexts provides intelligence on important topics, including environmental sample provenance, how to indicate the body decomposition timeline to support postmortem interval (PMI) and postmortem submersion interval (PMSI) estimates, and how to enhance identification of clandestine and transit grave locations. A diverse group of international experts have come together to present a clear perspective of forensic ecogenomics that encapsulates cutting-edge, topical and relevant cross-disciplinary approaches vital to the field.
  • Type 2 Diabetes and Dementia

    • 1st Edition
    • Velandai Srikanth + 1 more
    • English
    Type 2 Diabetes and Dementia details the relationship between diabetes, dementia and the future of medicine and therapeutics. Chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and the application of therapeutics. The book reflects the translational aspects of the current science in the field, with an emphasis on the display of neuroimaging and neuropathology. It contains contributions from world experts, and is ideal for clinicians and researchers in the fields of neurology, neuroscience, geriatric medicine and endocrinology.
  • Atlas of the Developing Rat Nervous System

    • 4th Edition
    • George Paxinos + 1 more
    • English
    Paxinos and Ashwell's Atlas of the Developing Rat Nervous System, Fourth Edition, builds on the many excellent features of previous editions that have made this book the most cited atlas of the developing rat brain. It provides the most comprehensive depiction of not only the structures in the brain and spinal cord, but also of the peripheral nervous system and target organs that are important for developmental neurobiologists, allowing the user to follow neural structures through the developing embryo in both time and space. The nomenclature and identification of structures in this edition have been thoroughly updated to ensure accuracy and compatibility.
  • Cardiovascular Outcomes of Treatments available for Patients with Type 1 and 2 Diabetes, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 47-1
    • Guillermo E. Umpierrez
    • English
    This issue of Endocrinology and Metabolism Clinics, edited by Dr. Guillermo E. Umpierrez, will focus on Cardiovascular Outcomes of Treatments available for Patients with Type 1 and 2 Diabetes. Topics include--but are not limited to--Diabetes and CAD and PVD; Prediabetes and CVD- DM prevention; Pathogenesis of atherosclerosis/CVD in diabetes Intensive Diabetes Treatment and CV Outcomes in T1D; Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes, Diabetes and Stroke; Cardiovascular outcome trials of glucose-lowering drugs or strategies in type 2 diabetes; Heart Failure in Diabetes Mellitus; Individualizing Glucose Lowering Therapy in the Patient with Diabetes and Heart Disease; Managing Dyslipidemia in Type 2 Diabetes; Blood pressure control and cardiovascular and renal outcomes; Hyperglycemia in acute coronary syndromes; Hospital Glucose Control; Managing Diabetes and cardiovascular risk in chronic kidney disease; and more.
  • Calcium Movement in Excitable Cells

    Pergamon Studies in The Life Sciences
    • 1st Edition
    • P. F. Baker + 1 more
    • English
    Calcium Movement in Excitable Cells, which is a second in a series, is a collection of articles taken from articles published in Progress in Biophysics and Molecular Biology, just like the first. The monograph is divided into two chapters. Chapter 1, Transport and Metabolism of Calcium Ions in Nerve, tackles the mechanisms responsible for maintaining the electrochemical gradient for calcium and effecting changes for the permeability of the cell membrane to calcium ions. Chapter 2, Divalent Cations as Charge Carriers in Excitable Membranes, tries to find out if divalent cations such as calcium, barium, and strontium can permeate excitable membranes. With two in-depth studies about movement of calcium as well as other cations and the factors behind it, the text is recommended to medical doctors, biologists, and biochemists who wish to learn more about this phenomenon.
  • Understanding Cancer from a Systems Biology Point of View

    From Observation to Theory and Back
    • 1st Edition
    • Irina Kareva
    • English
    Understanding Cancer from a Systems Biology Point of View: From Observation to Theory and Back starts with a basic question, why do we sometimes observe accelerated metastatic growth after resection of primary tumors? Next, it helps readers understand the systemic nature of cancer and how it affects treatment approaches and decisions. The book puts together aspects of cancer that many readers have most likely never combined, using unfamiliar, novel methods. It is a valuable resource for cancer researchers, cancer biologists, mathematicians and members of the biomedical field who are interested in applying systems biology methodologies for understanding and treating cancer.
  • Food Crop Production by Smallholder Farmers in Southern Africa

    Challenges and Opportunities for Improvement
    • 1st Edition
    • Ambayeba Muimba-Kankolongo
    • English
    Food Crop Production by Smallholder Farmers in Southern Africa: Challenges and Opportunities for Improvement evaluates traditional cultivation practices used by smallholder farmers, providing a synthesis of the latest information on increasing crop yield through adoption of research innovations. The book catalogs smallholder cultivation practices and recommends innovative strategies for improving the agriculture sector including: management practices that reduce net carbon emissions; technologies that improve soil structures and conserve the natural resources base; means of empowering female resources along value chains; and government commitment to adopt policies that enhance agriculture productivity by encouraging farmers to use environmentally sound cultivation technologies. Traditional farming techniques often produce negative impacts on the environment and ecosystem resulting in outbreaks of diseases and pests. In addition to the region’s recurrent droughts, these outbreaks of numerous diseases and pests, weeds and other invasive plants put thousands at risk of poverty and hunger, as well as malnutrition. This book presents enhanced agricultural production technologies for ensuring adequate food production, safety and nutritional quality for the population of Southern Africa and forms the basis for an increased SADC regional effort in food production through which financial and trade institutions can improve stakeholder capacities, encourage micro-enterprise development and enhance employment and regional trade.
  • Fundamentals of Weed Science

    • 5th Edition
    • Robert L Zimdahl
    • English
    Fundamentals of Weed Science, Fifth Edition, provides the latest information on this constantly advancing area of study. Placing weed management in the largest context of weed research and science, the book presents the latest advances in the role, control and potential uses of weed plants. From the emergence and genetic foundation of weeds, to the latest means of control and environmental impact, the book uses an ecological framework to explore the role of responsible and effective weed control in agriculture. In addition, users will find discussions of related areas where research is needed for additional understanding. Explored topics include the roles of culture, economics and politics in weed management, all areas that enable scientists and students to further understand the larger effects on society.
  • Veterinary Toxicology

    Basic and Clinical Principles
    • 3rd Edition
    • Ramesh C. Gupta
    • English
    Veterinary Toxicology, Basic and Clinical Principles, Third Edition, is a unique, single reference that teaches the basic principles of veterinary toxicology to any student at the DVM, MS or PhD level. While comparable texts are primarily directed on the field of human toxicology, this text thoroughly prepares toxicologists and students on the newest approaches for diagnosing chemical and plant poisoning cases in animals. Many chapters on topics not covered in any previous books are provided, such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology. Completely revised and updated to include the most recent developments in the field, including new toxins, methods and regions, this book is an essential resource for advanced students and researchers in toxicology, practicing veterinary toxicologists, poison control centers, marine biologists, environmentalists and animal scientists.
  • Forkhead FOXO Transcription Factors in Development and Disease

    • 1st Edition
    • Volume 127
    • English
    Forkhead FOXO Transcription Factors in Development and Disease, Volume 127, the latest release in the Current Topics in Developmental Biology series, provides a comprehensive set of reviews on transcription factors FOXO and their various functions in health and disease. Each chapter is contributed by a leading expert in the field, with specific sections covering Exceptional Longevity: Insights from Hydra to Humans, FOXO in neural cells and diseases of the nervous system, maintaining the equilibrium for better or for worse, and The Role of FoxOs in Bone Health and Disease, amongst other topics. This compilation provides a unique, up-to-date view of this enigmatic, highly evolutionary conserved family of transcription factors with a diverse array of functions in aging and longevity, cancer, and metabolism.
  • Foodborne Diseases

    • 1st Edition
    • Volume 15
    • Alexandru Mihai Grumezescu + 1 more
    • English
    Foodborne Diseases, Volume Fifteen, is the latest release in the Handbook of Bioengineering series. This volume covers the ever-changing complex issues that have emerged in the food industry over the past decade. This is a solid reference with broad coverage to provide a foundation for a practical understanding of diseases and related industrial applications. It will help researchers and scientists manage foodborne diseases and prevent and control outbreaks. The book provides information on the most common and classical foodborne diseases, their emergence and inquiries, along with the most investigated and successful strategies developed to combat these health-threatening conditions.
  • Actinobacteria: Diversity and Biotechnological Applications

    New and Future Developments in Microbial Biotechnology and Bioengineering
    • 1st Edition
    • Bhim Pratap Singh + 2 more
    • English
    Actinobacteria: Diversity and Biotechnological Applications: New and Future Developments in Microbial Biotechnology and Bioengineering, a volume in the series New and Future Developments in Microbial Biotechnology and Bioengineering series, offers the latest on the biotechnology of Kingdom actinobacteria, covering unique niches like their endosphere, rhizospheric soil and contaminated sites, etc. The book also covers the bioactive secondary metabolites obtained from actinobacteria and describes the application of microorganism (Actinobacteria) in plant growth promotion and in environmental cleanup. Finally, the book describes the biocontrol aspects of actinobacteria and how they can control fungal phytopathogens and the production of secondary metabolites.
  • Biophysical Basis of Physiology and Calcium Signaling Mechanism in Cardiac and Smooth Muscle

    • 1st Edition
    • Tetsuya Watanabe
    • English
    Biophysical Basis of Physiology and Calcium Signaling Mechanism in Cardiac and Smooth Muscle acts as a bridge between physiology and physics by discussing the physiology and calcium signaling mechanism in cardiac and smooth muscle. By exploring the mechanism of the cyclic release of stored Ca^(2+) in the SR or ER, this book covers the cell communication system, including excitable cells, recognizing the most relevant mechanisms of cell communication. Serving as a bridge between physiology and physics, coverage spans the physiology and calcium signaling mechanism in cardiac and smooth muscle, offering insight to physiological scientists, pharmaceutical scientists, medical doctors, biologists and physicists.
  • Systems Evolutionary Biology

    Biological Network Evolution Theory, Stochastic Evolutionary Game Strategies, and Applications to Systems Synthetic Biology
    • 1st Edition
    • Bor-Sen Chen
    • English
    Systems Evolutionary Biology: Biological Network Evolution Theory, Stochastic Evolutionary Game Strategies, and Applications to Systems Synthetic Biology discusses the evolutionary game theory and strategies of nonlinear stochastic biological networks under random genetic variations and environmental disturbances and their application to systematic synthetic biology design. The book provides more realistic stochastic biological system models to mimic the real biological systems in evolutionary process and then introduces network evolvability, stochastic evolutionary game theory and strategy based on nonlinear stochastic networks in evolution. Readers will find remarkable, revolutionary information on genetic evolutionary biology that be applied to economics, engineering and bioscience.
  • Hidden Persuaders in Cocoa and Chocolate

    A Flavor Lexicon for Cocoa and Chocolate Sensory Professionals
    • 1st Edition
    • Renata Januszewska
    • English
    Hidden Persuaders of Cocoa and Chocolate: A Flavor Lexicon for Cocoa and Chocolate Sensory Professionals provides an overview of the tastes, aromas and notes describing cocoa and chocolate. In addition to exploring tastes, aromas and notes, the book broadens the language for describing chocolate by relating tasting experiences to the process of pairing flavors. This resource, designed for both academics and those working in research and development, equips the reader to describe these attributes in a sensory language for the purposes of new product development or quality improvement.
  • Neurogenetics, Part II

    • 1st Edition
    • Volume 148
    • English
    Neurogenetics, Part II, Volume 148, the latest release in the Handbook of Clinical Neurology, provides the latest information on the genetic methodologies that are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is expected to dramatically grow in scope. Part II builds on the foundation of Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phacomatoses.
  • Sirtuins in Health and Disease

    • 1st Edition
    • Volume 154
    • English
    Sirtuins in Health and Disease, Volume 154 presents the reactions catalyzed by sirtuins in terms of their unique coenzyme NAD+-dependent catalytic mechanisms, the ways to elucidate these mechanisms, and the design of the inhibitory compounds against the sirtuin-catalyzed reactions as potential therapeutic agents for human diseases. Sections cover the concepts and chemical tools in sirtuin research, SIRT4 and SIRT7, the regulatory effects of NAD metabolic pathways on sirtuin activity, sirtuins as modifiers of Huntington’s Disease (HD) pathology, parasite sirtuins as targets for novel chemotherapeutic agents, targeting sirtuins – substrate specificity and inhibitor design, and chemical probes in sirtuin research. This book focuses on the outstanding issues in the sirtuin field and implications for future sirtuin research.
  • Sustainable Recovery and Reutilization of Cereal Processing By-Products

    • 1st Edition
    • Charis M. Galanakis
    • English
    Sustainable Recovery and Reutilization of Cereal Processing By-Products addresses topics associated with the sustainable management of cereal manufacturing. Emphasis is placed on current, advisable practices, general valorization techniques of cereal processing by-products, and the functional properties of healthy cereal by-product components that lead to target applications in foods and nutraceuticals. Focus includes discussions on wheat bran, distillers' dried grains—based within the biorefinery concept, and different techniques for the separation, extraction, recovery and formulation of valuable compounds, including proteins, arabinoxylans, and beta-glucan.
  • Plastid Genome Evolution

    • 1st Edition
    • Volume 85
    • English
    Plastid Genome Evolution, Volume 85 provides a summary of recent research on plastid genome variation and evolution across photosynthetic organisms. It covers topics ranging from the causes and consequences of genomic changes, to the phylogenetic utility of plastomes for resolving relationships across the photosynthetic tree of life. This newly released volume presents thorough, up-to-date information on coevolution between the plastid and nuclear genomes, with chapters on plastid autonomy vs. nuclear control over plastid function, establishment and genetic integration of plastids, plastid genomes in alveolate protists, plastid genomes of glaucophytes, the evolution of the plastid genome in chlorophyte and streptophyte green algae, and more.
  • Advances in Biotechnology for Food Industry

    • 1st Edition
    • Volume 14
    • Alexandru Mihai Grumezescu + 1 more
    • English
    Advances in Biotechnology for Food Industry, Volume Fourteen in the Handbook of Food Bioengineering series, provides recent insight into how biotechnology impacts the global food industry and describes how food needs are diverse, requiring the development of innovative biotechnological processes to ensure efficient food production worldwide. Many approaches were developed over the last 10 years to allow faster, easier production of widely used foods, food components and therapeutic food ingredients. This volume shows how biotechnological processes increase production and quality of food products, including the development of anti-biofilm materials to decrease microbial colonization in bioreactors and food processing facilities.
  • Inmunología básica para medicina

    • 1st Edition
    • Isabel Olazabal Olarreaga + 1 more
    • Spanish
    Manual conciso que destaca la información más útil para el médico y expone los temas de actualidad para estudiantes y profesionales en los fundamentos de la Inmunología. El contenido más importante de la obra es: 24 temas de inmunología básica con información clínica complementaria; 4 anexos sobre patógenos, trasplantes, oncología y vacunas; cuadros con aspectos de interés generales y médicos, así como resúmenes al final de cada capítulo; guías de seminarios para ayudar a integrar conocimientos; material de carácter molecular esencial; profusamente ilustrado, para ayudar a fijar conceptos inmunológicos. Dirigida a estudiantes de Medicina, médicos de cualquier especialidad y estudiantes de otros grados de ciencias de la salud que necesiten ponerse al día en esta materia de una manera breve, clara y desarrollada de forma que se facilita el autoaprendizaje.
  • International Review of Cell and Molecular Biology

    • 1st Edition
    • Volume 336
    • English
    International Review of Cell and Molecular Biology. Volume 336 reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. This updated volume includes specific chapters on Membrane trafficking in autophagy, Targeting the metabolism of leukemic cells, Autophagic flux in Alzheimer's disease, Transcriptional alterations associated with celiac disease, and the Regulation of antitumor immunity by IDO1, amongst other timely topics. The articles published in IRCMB have a high impact and an average cited half-life of 9 years. This great resource ranks high amongst scientific journals dealing with cell biology.
  • Advances in Cancer Research

    • 1st Edition
    • Volume 137
    • English
    Advances in Cancer Research, Volume 137, the latest release in this ongoing, well-regarded serial provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents original reviews on research bridging oncology and gene expression, with this volume covering unconventional approaches to modulating the immunogenicity of tumor cells, tumor dormancy and immunoediting, the emerging role of anti-apoptotic Bcl-2 family proteins in chemoresistance, Beclin-1 and autophagy, MDA-7/IL-24, and nanotechnology and medicine.
  • Protein-Protein Interactions in Human Disease, Part A

    • 1st Edition
    • Volume 110
    • English
    Protein-Protein Interactions in Human Disease, Part A, Volume 110 aims to promote further research and development in the protein interaction network as a means to not only identify the critical proteins involved in the etiology of human diseases, but also identify new protein targets for drug development. Sections cover such topics as protein-protein interaction modulators for epigenetic therapies, intrinsic disorder, protein-protein interactions and disease, targeting protein-protein interactions in the ubiquitin-proteasome pathway, the proteomics of occupational diseases, and computational methods in predicting the impact of SNPs in protein-protein network, amongst other topics.
  • Food Quality: Balancing Health and Disease

    • 1st Edition
    • Volume 13
    • Alexandru Mihai Grumezescu + 1 more
    • English
    Food Quality: Balancing Health and Disease, Volume Thirteen in the Handbook of Food Bioengineering series, provides essential information for researchers, scientists and students on the relationship between the quality of foods and disease at the biological level. It presents different technological approaches to detect food properties and their capabilities for balancing health and disease to deliver high-quality products to consumers. This volume explores the dynamic potential of how food bioengineering can improve traditional foods through modern methods to make a positive impact on human health and foster innovation.
  • The Role of Global Air Pollution in Aging and Disease

    Reading Smoke Signals
    • 1st Edition
    • Caleb E. Finch
    • English
    Global Air Pollution in Aging: Reading Smoke Signals is a complete reference connecting environmental pollution research to the human aging process. Since 1800, lifespans have more than doubled as infections declined and medicine improved. But the 20th century introduced a new global scourge of air pollution from fossil fuels with the potential to damage arteries, hearts and lungs that has been related to chronic exposure of air pollution from fossil fuels. Risk areas of study include childhood obesity, brain damage associated with air pollution, increased risk for autism in children and dementia in older adults. In humans and animals, air pollution stimulates chronic inflammation in different organs, and genetic vulnerability to air pollution is being recognized, particularly for carriers of the Alzheimer risk gene ApoE4.
  • Skin and Arthropod Vectors

    • 1st Edition
    • Nathalie Boulanger
    • English
    Recent research on skin immunity and the skin microbiome reveals the complexity of the skin and its importance in the development of immunity against arthropod-borne diseases. In diseases such as malaria, borreliosis, leishmaniasis, trypanosomiasis, etc., the skin interface has been shown as an essential site for pathogens to hide from the immune system, and as a potential site of persistence. Only very few vaccines have been successfully developed so far against these diseases, likely because of an insufficient understanding on the development of skin immunity against pathogens. Skin and Arthropod Vectors expands our knowledge on the role of the skin interface during the transmission of arthropod-borne diseases and particularly its immunity. This work may support researchers who strive for developing more efficient diagnostic tools and vaccines. It also gives scientists and advanced students working in related areas a better insight on how humans and animals are attractive to arthropods to develop better repellents, or to set up transgenic arthropods.
  • Fe-S Cluster Enzymes Part B

    • 1st Edition
    • Volume 599
    • English
    Methods in Enzymology, Volume 599 is the second of two volumes focused on Fe-S cluster enzymes. Topics of interest in this new release include steps towards understanding mitochondrial Fe/S cluster biogenesis, iron sulfur clusters in zinc finger proteins, electrochemistry of Iron-sulfur enzymes, NRVS for Fe in biology and its experiment and basic interpretation, methods for studying iron regulatory protein 1, an important protein in human iron metabolism, the characterization of glutaredoxin Fe-S cluster binding interactions using circular dichroism spectroscopy, fluorescent reporters to track Fe-S cluster assembly and transfer reactions, methods for studying the Fe-S cluster containing base excision repair glycosylase MUTYH, and more.
  • The Nature and Use of Ecotoxicological Evidence

    Natural Science, Statistics, Psychology, and Sociology
    • 1st Edition
    • Michael C. Newman
    • English
    The Nature and Use of Ecotoxicological Evidence: Natural Science, Statistics, Psychology, and Sociology examines how toxicologists and environmental professionals come to understand and make decisions about possible harm from pollutants. Drawing on concepts and techniques from the natural, social and mathematical sciences, the book emphasizes how pollutant-related evidence is gathered, assessed, communicated and applied in decision-making. Each chapter begins with a real-world example before exploring fundamental cognitive, social, statistical or natural science concepts to explain the opening example. Methods from other disciplines for recognizing, reducing or removing the influence of impediments in wise decision-making are highlighted in each chapter. Misreading evidence by the scientific community, and miscommunication to regulators and the public, remain major impediments to wise action in pollution issues. Which evidence comes to dominate the dialogue among scientists, regulators and decision makers depends on social and scientific dynamics. Yet psychological and sociological factors that influence the movement of evidence through scientific communities to regulators receive cursory discussion by professionals unfamiliar with the sociology literature. Toxicologists, environmental scientists, psychologists and professionals and students across the sciences will find the book useful for understanding how evidence is generated, assessed and communicated in their own fields.
  • Apprentices to Genius: A tribute to Solomon H. Snyder

    • 1st Edition
    • Volume 82
    • English
    Apprentices to Genius: A tribute to Solomon H. Snyder, a volume in the Advances in Pharmacology series, presents a tribute to Dr. Solomon H. Snyder, highlighting chapters submitted from a broad range of his students. It covers many different areas of neuroscience and pharmacology, with this volume exploring how receptor binding and drug discovery, the emerging role of glutamate in the pathophysiology of mental illness, nitric oxide signaling in neurodegeneration and cell death, carboxypeptidase E and the identification of novel neuropeptides as potential therapeutic targets, the regulation of mitochondrial functions by TSPO, clozapine and its translational investigation, and more.
  • Endothelium and Cardiovascular Diseases

    Vascular Biology and Clinical Syndromes
    • 1st Edition
    • Protasio L. Da Luz + 3 more
    • English
    Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians.
  • Lifestyle in Heart Health and Disease

    • 1st Edition
    • Ronald Ross Watson + 1 more
    • English
    Lifestyle and Heart Health and Disease provides a comprehensive evaluation of lifestyle factors that modify heart function and structure. It includes coverage of a wide range of lifestyle factors, including physical activity, alcohol, tobacco, drugs of abuse, nutrition and psychosocial factors. The book clearly presents the scientific evaluation of published research relating to general responses by scientists, physicians and patients, along with new research on the role of lifestyle in the prevention, amelioration and causation of cardiac remodeling and disease.
  • Thyroid Hormone

    • 1st Edition
    • Volume 106
    • English
    Thyroid hormone, Volume 106, the latest release in the Vitamins and Hormones series first published in 1943 provides up-to-date information on crystal structures and basic structural studies on neurotrophins and their receptors, neurotrophin functions and the biological actions of neurotrophins related to clinical conditions and disease. This new release focuses on timely topics, including the Nuclear Import and Export of the Thyroid Hormone Receptor, the Thyroid hormone and the white matter of the central nervous system: from development to repair, Thyroid hormone and astrocyte differentiation, and the Molecular Basis of Nongenomic Actions of Thyroid Hormone, amongst other topics.
  • Long Non-coding RNA

    The Dark Side of the Genome
    • 1st Edition
    • Antonin Morillon
    • English
    The dark side of the genome represents vast domains of the genome that are not encoding for proteins – the basic bricks of cellular structure and metabolism. Up to 98% of the human genome is non-coding and produces so-called long non-coding RNA. Some of these non-coding RNA play fundamental roles in cellular identity, cell development and cancer progression. They are now widely studied in many organisms to understand their function. This book reviews this expanding field of research and present the broad functional diversities of those molecules and their putative fundamental and therapeutic roles and develops the recent history of non-coding RNA, their very much debated classification and how they raise a formidable interest for developmental and tumorigenesis biology. Using classical examples and an extensive bibliography, the book illustrates the most studied and attractive examples of these long non-coding RNA, how they interface with epigenetics, genome integrity and expression and what are the current models of their regulatory mechanisms.
  • Understanding Intuition

    A Journey In and Out of Science
    • 1st Edition
    • Lois Isenman
    • English
    Understanding Intuition: A Journey In and Out of Science explores the biological and cognitive mechanisms that account for intuition, and examines the first-person experience. The book integrates both scientific and personal perspectives on this important yet elusive mental capacity. It uses specific encounters to illustrate that intuition is enhanced when we can attend to the subtle aspects of our inner experiences, such as bodily sensations, images, and differing kinds of intuitive evaluative feelings, all of which may emerge no further than on the fringe of awareness. This awareness of subtle inner experiences helps forge a more fluid exchange between the unconscious and conscious minds, and allows readers to calibrate their own intuitions. Over the course of the book, readers will gain a deeper appreciation and respect for the unconscious mind and its potential sophistication, and even its potential wisdom. Understanding Intuition is a timely and critical resource for students and researchers in psychology, cognitive science, theology, women’s studies, and neuroscience.
  • Bioactive Seaweeds for Food Applications

    Natural Ingredients for Healthy Diets
    • 1st Edition
    • Yimin Qin
    • English
    Bioactive Seaweed Substances for Functional Food Applications: Natural Ingredients for Healthy Diets presents various types of bioactive seaweed substances and introduces their applications in functional food products. Presenting summaries of the substances derived from seaweed, this book systematically explores new ingredients and the bioactive substances that are both environmentally friendly and highly beneficial to human health. This evidence-based resource offers an abundance of information on the applications of seaweed as a solution to meet an increasing global demand for sustainable food sources. It is an essential reference for anyone involved in seaweed substance research, seaweed processing, and food and health disciplines.
  • Soft Computing Based Medical Image Analysis

    • 1st Edition
    • Nilanjan Dey + 3 more
    • English
    Soft Computing Based Medical Image Analysis presents the foremost techniques of soft computing in medical image analysis and processing. It includes image enhancement, segmentation, classification-based soft computing, and their application in diagnostic imaging, as well as an extensive background for the development of intelligent systems based on soft computing used in medical image analysis and processing. The book introduces the theory and concepts of digital image analysis and processing based on soft computing with real-world medical imaging applications. Comparative studies for soft computing based medical imaging techniques and traditional approaches in medicine are addressed, providing flexible and sophisticated application-oriented solutions.