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Elsevier

Books in Life sciences

  • Advanced Issue Resolution in Safety Pharmacology

    • 1st Edition
    • Mary Jeanne Kallman + 1 more
    • English
    Advanced Issue Resolution in Safety Pharmacology not only discusses unique issues that may emerge during the development of new medicines, but also provides detailed insights on how to resolve them. The book employs a valuable strategy that integrates preclinical findings with the clinical resolution of those findings. In addition, it introduces key interdisciplinary topics in an accessible and systematic format. Edited and written by leaders in the field of safety pharmacology, this book considerably advances the discussion on issue resolution topics, thus raising them to the next level of importance by providing scientists with an indispensable resource on solving safety issues.

  • Animal Models for Examining Social Influences on Drug Addiction

    • 1st Edition
    • Volume 140
    • English
    Animal Models for Examining Social Influences on Drug Addiction, Volume 140 in the International Review of Neurobiology series, provides insights on social factors that mediate drug addiction. This book discusses current research and projects, with specific chapters focusing on Social Influences on Nicotine-related Behaviors in Rodents, Models of Alcohol Intake in Social Contexts, Social Factors in Ethanol Sensitization, Social Modulation of Heroin Intake, Amphetamines and Social Aspects of Addiction, Amphetamines and Social Aspects of Addiction, Social Models of Cannabis Use, Oxytocin and Rodent Models of Addiction, Social Place Preference and Reward, Social Defeat Stress, and more.

  • Whooping Cranes: Biology and Conservation

    Biodiversity of the World: Conservation from Genes to Landscapes
    • 1st Edition
    • English
    Whooping Cranes: Biology and Conservation covers one of the most endangered birds in North America, and the subject of intense research and highly visible conservation activity. The volume summarizes current biological information on Whooping Cranes and provides the basis for future research necessary for conservation of this species. This edited volume concentrates on work completed in the past 20 years in the areas of population biology, behavior and social structure, habitat use, disease and health, captive breeding, and Whooping Crane conservation. Much of the information presented comes from the study and management of remnant and reintroduced populations of Whooping Cranes in the field; some information is from experimentation and breeding of captive Whooping Cranes. Whooping Cranes: Biology and Conservation seeks to inform and galvanize action dedicated to meeting the challenges faced by Whooping Crane managers and conservationists. Thus, it describes one model of endangered species conservation and restoration that will interest a wide audience: professionals that work on cranes; researchers in the fields of small population biology, endangered species, and avian ecology; wildlife veterinarians and those involved in avian husbandry; administrators of management agencies or conservation organizations; conservationists in other fields; teachers of conservation biology or ornithology and their students; and the educated general public.

  • Whey Proteins

    From Milk to Medicine
    • 1st Edition
    • Hilton C Deeth + 1 more
    • English
    Whey Proteins: From Milk to Medicine addresses the basic properties of whey proteins including chemistry, analysis, heat sensitivity, interactions with other proteins and carbohydrates, modifications (hydrolysis, aggregation, conjugation), their industrial preparation, processing and applications, quality aspects including flavour and effects of storage, as well as their role in nutrition, sports and exercise, and health and wellness. Readers of Whey Proteins will gain a better understanding of the chemical nature of the various whey proteins in cow’s milk and the milk of other species. This includes their unique physical and functional properties; the industrial processes used to extract them from milk, to process them into various forms, and to modify them to enhance their functionality; and their nutritive value and application in the fields of sports and exercise science, infant nutrition and medicine. This book is an essential resource for food and nutrition researchers, dairy and food companies, pharmaceutical organizations, and graduate students.

  • Encyclopedia of Biomedical Engineering

    • 1st Edition
    • Roger Narayan
    • English
    Encyclopedia of Biomedical Engineering, Three Volume Set is a unique source for rapidly evolving updates on topics that are at the interface of the biological sciences and engineering. Biomaterials, biomedical devices and techniques play a significant role in improving the quality of health care in the developed world. The book covers an extensive range of topics related to biomedical engineering, including biomaterials, sensors, medical devices, imaging modalities and imaging processing. In addition, applications of biomedical engineering, advances in cardiology, drug delivery, gene therapy, orthopedics, ophthalmology, sensing and tissue engineering are explored. This important reference work serves many groups working at the interface of the biological sciences and engineering, including engineering students, biological science students, clinicians, and industrial researchers.

  • Handbook of in Vivo Neural Plasticity Techniques

    A Systems Neuroscience Approach to the Neural Basis of Memory and Cognition
    • 1st Edition
    • Volume 28
    • English
    Handbook of in Vivo Neural Plasticity Techniques, Volume 28: A Systems Neuroscience Approach to the Neural Basis of Memory and Cognition gives a comprehensive overview of the current methods and approaches that are used to study neural plasticity from a systems neuroscience perspective. In addition, the book offers in-depth methodological advice that provides the necessary foundation for researchers establishing methods and students who need to understand the theoretical and methodological bases of these approaches. This is the ideal resource for anyone new to the study of cognitive and behavioral neuroscience who seeks an introduction to state-of-the-art techniques.

  • Pathology of Wildlife and Zoo Animals

    • 1st Edition
    • Karen A. Terio + 2 more
    • English
    Pathology of Wildlife and Zoo Animals is a comprehensive resource that covers the pathology of wildlife and zoo species, including a wide scope of animals, disease types and geographic regions. It is the definitive book for students, biologists, scientists, physicians, veterinary clinicians and pathologists working with non-domestic species in a variety of settings. General chapters include information on performing necropsies, proper techniques to meet the specialized needs of forensic cases, laboratory diagnostics, and an introduction into basic principles of comparative clinical pathology. The taxon-based chapters provide information about disease in related groups of animals and include descriptions of gross and histologic lesions, pathogenesis and diagnostics. For each group of animals, notable, unique gross and microscopic anatomical features are provided to further assist the reader in deciding whether differences from the domestic animal paradigm are "normal." Additional online content, which includes text, images, and whole scanned glass slides of selected conditions, expands the published material resulting in a comprehensive approach to the topic.

  • Handbook of Pharmaceutical Wet Granulation

    Theory and Practice in a Quality by Design Paradigm
    • 1st Edition
    • Ajit S. Narang + 1 more
    • English
    Handbook of Pharmaceutical Wet Granulation: Theory and Practice in a Quality by Design Paradigm offers a single and comprehensive reference dedicated to all aspects of pharmaceutical wet granulation, taking a holistic approach by combining introductory principles with practical solutions. Chapters are written by international experts across industry, academic and regulatory settings, and cover a wide spectrum of relevant and contemporary wet granulation topics, techniques and processes. The books' focus on process analytical technology, quality by design principles, granulation equipment, modeling, scale-up, control and real time release makes it a timely and valuable resource for all those involved in pharmaceutical wet granulation.

  • A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics

    From the Bench to the Clinic
    • 1st Edition
    • Xiao-Dong Chen
    • English
    A Roadmap to Non-hematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic is a resource that provides an overview of the principles of stem cell therapy, the promises and challenges of using stem cells for treating various clinical conditions, and future perspectives. The overall goal is to facilitate the translation of basic research on stem cells to clinical applications. The properties of stem cells from various sources are reviewed and the advantages and disadvantages of each for clinical use are discussed. Modifying stem cell properties through preconditioning strategies using physical, chemical, genetic, and molecular manipulation to improve cell survival, increase cell differentiation potential, enhance production of paracrine factors, and facilitate homing to the site of injury or disease upon transplantation are reviewed. Various routes of stem cell administration and dosing, and the duration of effects, are explored. Individual chapters are written by experts in the field and focus on the use of stem cells in treating various degenerative diseases, autoimmune diseases, wound healing, cardiovascular disease, spinal cord injury, oral and dental diseases, and skeletal disorders. Finally, experts in the regulatory arena discuss mechanisms used in different countries for approving the use of stem cells to treat diseases and many common issues that are typically encountered while seeking approval for this class of therapeutic agent.

  • Enzymes in Synthetic Biology

    • 1st Edition
    • Volume 608
    • English
    Volume 608 of the series Methods in Enzymology covers key aspects of enzyme discovery, engineering tools and platforms, and examples of applications in the enzymology of synthetic biology.

  • Institutions as Conscious Food Consumers

    Leveraging Purchasing Power to Drive Systems Change
    • 1st Edition
    • Sapna Elizabeth Thottathil + 1 more
    • English
    Institutions like schools, hospitals, and universities are not well known for having quality, healthy food. In fact, institutional food often embodies many of the worst traits of our industrialized food system, with long supply chains that are rife with environmental and social problems and growing market concentration in many stages of food production and distribution. Recently, however, non-profit organizations, government agencies, university research institutes, and activists have partnered with institutions to experiment with a wide range of more ethical and sustainable models for food purchasing, also known as values-based procurement. Institutions as Conscious Food Consumers brings together in-depth case studies from several of promising models of institutional food purchasing that aim to be more sustainable, healthy, equitable, and local. With chapters written by a diverse set of authors, including leaders in the food movement and policy researchers, this book: Documents growing interest among non-profit organizations and activists in institutional food interventions through case studies and first-hand experiences; Highlights emerging evidence about how these new procurement models affect agro-food supply chains; and Examines the role of policy and regional or geographic identity in promoting food systems change. Institutions as Conscious Food Consumers makes the case that institutions can use their budgets to change the food system for the better, although significant challenges remain. It is a must read for food systems practitioners, food chain researchers, and foodservice professionals interested in values-based procurement.

  • Human Reproductive and Prenatal Genetics

    • 1st Edition
    • Peter C.K. Leung + 1 more
    • English
    Human Reproductive and Prenatal Genetics presents the latest material from a detailed molecular, cellular and translational perspective. Considering its timeliness and potential international impact, this all-inclusive and authoritative work is ideal for researchers, students, and clinicians worldwide. Currently, there are no comprehensive books covering the field of human reproductive and prenatal genetics. As such, this book aims to be among the largest and most useful references available. Named a Highly Commended book in the Basic and Clinical Sciences by the British Medical Association.

  • Microfluidics in Cell Biology Part B: Microfluidics in Single Cells

    • 1st Edition
    • Volume 147
    • English
    Microfluidics in Cell Biology Part B: Microfluidics in Single Cells, Volume 147, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are three sections on microfluidics in various single cell models, including microfludics in micro-organisms, microfluidics for cell culture and cell sorting of mammalian cells, and microfluidics for cell migration. Specific sections in this latest release include Temperature control and drug delivery for cell division cycle control in fission yeast H2O2 stress response in budding yeast, Antibiotic resistance in bacteria, Metabolism in bacteria, Fluidized beds for bacterial sorting and amplification, Microfluidics for cell culture and cell sorting of mammalian cells, Hydrogel microwells, Immune cells migration in complex environments, Neutrophiles migration in health and disease, Cell guidance by physical cues, Stable gradients in gels of extracellular matrix for cancer cell migration, and more.

  • Neural Mechanisms of Addiction

    • 1st Edition
    • Mary Torregrossa
    • English
    Neural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research.

  • Computational Molecular Modelling in Structural Biology

    • 1st Edition
    • Volume 113
    • English
    Computational Molecular modelling in Structural Biology, Volume 113, the latest release in the Advances in Protein Chemistry and Structural Biology, highlights new advances in the field, with this new volume presenting interesting chapters on charting the Bromodomain BRD4: Towards the Identification of Novel Inhibitors with Molecular Similarity and Receptor Mapping, and Computational Methods to Discover Compounds for the Treatment of Chagas Disease.

  • Neurobiology of the Placebo Effect Part II

    • 1st Edition
    • Volume 139
    • English
    Neurobiology of the Placebo Effect, Part II, Volume 139, the latest release in the International Review of Neurobiology series, is the second part of a two-volume set that provides the latest placebo studies in clinically relevant models. Specific chapters cover the History of placebo effects in medicine, Lumping or Splitting: Towards a taxonomy of placebo and related effects, Theories and brain mechanisms of placebo analgesia, Pain Modulation: From CPM to placebo and nocebo effects in experimental and clinical pain, Modulation of the motor system by placebo and nocebo effects, and the role of sleep in learning placebo effects, amongst other topics.

  • Phosphatases

    • 1st Edition
    • Volume 607
    • English
    Methods in Enzymology, Volume 607: Phosphatases, the latest release in this ongoing series, highlights new advances in the field as detailed by an international board of authors. This latest release includes chapters on Empirical Valence Bond Simulations of the Evolution of Enzyme Function, QM/MM Free Energy and Kinetic Isotope Analysis of Phosphoryl Transfer in Enzymes, the Structural, Mechanism and Evolution of Phosphatases, How to Define Rapid Motions in Pumping Pyrophosphatases, The Evolution of K+-Independence in Pyrophosphatases, the Crystallization of Michaelis, Intermediate and Inhibited Complexes in Phosphatases, and an Investigation of Nucleotide Loading and Effector Binding of K-Ras.

  • Goal-Directed Decision Making

    Computations and Neural Circuits
    • 1st Edition
    • Richard W. Morris + 2 more
    • English
    Goal-Directed Decision Making: Computations and Neural Circuits examines the role of goal-directed choice. It begins with an examination of the computations performed by associated circuits, but then moves on to in-depth examinations on how goal-directed learning interacts with other forms of choice and response selection. This is the only book that embraces the multidisciplinary nature of this area of decision-making, integrating our knowledge of goal-directed decision-making from basic, computational, clinical, and ethology research into a single resource that is invaluable for neuroscientists, psychologists and computer scientists alike. The book presents discussions on the broader field of decision-making and how it has expanded to incorporate ideas related to flexible behaviors, such as cognitive control, economic choice, and Bayesian inference, as well as the influences that motivation, context and cues have on behavior and decision-making.

  • Oxidants, Antioxidants, and Impact of the Oxidative Status in Male Reproduction

    • 1st Edition
    • Ralf Henkel + 2 more
    • English
    Oxidants, Antioxidants and Impact of the Oxidative Status in Male Reproduction is an essential reference for fertility practitioners and research and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology. The book focuses on unravelling the pathophysiology of oxidative stress mediated male infertility, recruiting top researchers and clinicians to contribute chapters. This collection of expertise delves into the physico-chemical aspects of oxidative stress, including a new focus on reductive stress. Furthermore, the inclusion of clinical techniques to determine oxidative stress and the OMICS of reductive oxidative stress are also included. This is a must-have reference in the area of oxidative stress and male reproductive function.

  • Enzymes in Food Biotechnology

    Production, Applications, and Future Prospects
    • 1st Edition
    • Mohammed Kuddus
    • English
    Enzymes in Food Biotechnology: Production, Applications, and Future Prospects presents a comprehensive review of enzyme research and the potential impact of enzymes on the food sector. This valuable reference brings together novel sources and technologies regarding enzymes in food production, food processing, food preservation, food engineering and food biotechnology that are useful for researchers, professionals and students. Discussions include the process of immobilization, thermal and operational stability, increased product specificity and specific activity, enzyme engineering, implementation of high-throughput techniques, screening to relatively unexplored environments, and the development of more efficient enzymes.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 86
    • English
    Advances in Clinical Chemistry, Volume 86, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Biodiversity of Fishes in Arunachal Himalaya

    Systematics, Classification, and Taxonomic Identification
    • 1st Edition
    • Achom Darshan Singh + 2 more
    • English
    Biodiversity of Fishes in Arunachal Himalaya: Systematics, Classification, and Taxonomic Identification provides a detailed piscatorial resource of the fish species living in the rich mountain waterbodies of the eastern Himalayan region. It presents the latest classifications and updated taxa of fish dwelling in high-altitude cold waters, mid-altitude cold and warm waters, and warm waters in the low altitude foothill regions of the Arunachal Himalaya. The book includes the scientific and vernacular names of more than 200 fish species, as well as coloration, distributional and conservational status. It addresses increasing threats to the endemic fishes of this region, including habitat shrinkage, habitat destruction, and more. This book will be a valuable resource for biodiversity and conservation researchers, especially those specializing in ichthyo-faunal diversity. Fishery researchers and students will also find the information presented on taxonomic and classification very useful to their initiatives.

  • Breeding Sorghum for Diverse End Uses

    • 1st Edition
    • Aruna C + 3 more
    • English
    Breeding Sorghum for Diverse End Uses is a comprehensive overview of all significant global efforts for the genetic improvement of sorghum, a major crop of many semi-arid nations that is suitable for a huge range of uses, from human food, to biofuels. Split into two main sections, the book initially reviews the genetic suitability of sorghum for breeding, also providing the history of the genetic improvement of the grain. Finally, other sections look at specific breeding programs that could be improved in a number of areas, including human food, animal feed and industrial usage. Readers in academics, research, plant genetics and sorghum development will find this resource of great value. In addition, it is essential reading for engineers who utilize sorghum for food, feed and industrial materials in industry.

  • Drug Delivery Nanosystems for Biomedical Applications

    • 1st Edition
    • Chandra P. Sharma
    • English
    Drug Delivery Nanosystems for Biomedical Application reviews some of the most challenging nanosystems with different routes of delivery that are useful for specific drugs, from both efficacy and bioavailability points-of-view. The chapters explore how this area is developing, the present state of the field, and future developments, in particular, inorganic, metallic, polymeric, composite and lipid nanosystems and their possible evolution to clinical applications. The book is a valuable research reference for both researchers and industrial partners who are not only interested in learning about this area, but also want to gain insights on how to move towards translational research.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 104
    • English
    Advances in Applied Microbiology, Volume 104, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas, with this updated volume including chapters covering Cold Shock Responses in Salmonella, Microbial Processes in Geotechnical Engineering, Microbial Diversity and Functional Analysis, The Mycosphere and Turnover of Contaminants, and the Enhancement of Metallosphaera Sedula Bioleaching by Targeted Recombination and Adaptive Laboratory Evolution.

  • Risk Assessment for Human Metal Exposures

    Mode of Action and Kinetic Approaches
    • 1st Edition
    • Gunnar F. Nordberg + 1 more
    • English
    Risk Assessment for Human Metal Exposures: Mode of Action and Kinetic Approaches examines the current principles of risk assessment in human metal exposures, with a focus on Mode of Action(MOA), Toxicokinetic and Toxicodynamic (TKTD) considerations, and computer models. Derived from the highly respected Handbook on the Toxicology of Metals, Fourth Edition (2014), the book summarizes principles and methods and provides examples of how MOA –TKTD can be used. In addition, it presents tactics on how information generated by such methods can be confirmed by epidemiological data. Furthermore, it demonstrates how epidemiological data can be confirmed and evaluated by the examined models and considerations. This resource uniquely integrates several important topics, such as risk assessment, characterization, management and communication—the classic risk assessment paradigm—with mode of action, TKTD, and epidemiology, all topics related to human exposure. Written by pioneers in the field, this book is an essential reference for researchers, students and technicians in toxicology and risk assessment.

  • Encyclopedia of Bioinformatics and Computational Biology

    ABC of Bioinformatics
    • 1st Edition
    • Shoba Ranganathan + 2 more
    • English
    Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries.

  • Bioethanol Production from Food Crops

    Sustainable Sources, Interventions, and Challenges
    • 1st Edition
    • Ramesh C. Ray + 1 more
    • English
    Bioethanol Production from Food Crops: Sustainable Sources, Interventions and Challenges comprehensively covers the global scenario of ethanol production from both food and non-food crops and other sources. The book guides readers through the balancing of the debate on food vs. fuel, giving important insights into resource management and the environmental and economic impact of this balance between demands. Sections cover Global Bioethanol from Food Crops and Forest Resource, Bioethanol from Bagasse and Lignocellulosic wastes, Bioethanol from algae, and Economics and Challenges, presenting a multidisciplinary approach to this complex topic. As biofuels continue to grow as a vital alternative energy source, it is imperative that the proper balance is reached between resource protection and human survival. This book provides important insights into achieving that balance.

  • Noninvasive Prenatal Testing (NIPT)

    Applied Genomics in Prenatal Screening and Diagnosis
    • 1st Edition
    • Lieve Page-Christiaens + 1 more
    • English
    Since its introduction in 2012, cell-free (cf) DNA based Non-Invasive Prenatal Testing (NIPT) has been employed to test for fetal chromosome abnormalities, and gene mutations that lead to a variety of genetic conditions, by millions of pregnant women, in more than 90 countries worldwide. With Noninvasive Prenatal Testing (NIPT): Applied Genomics in Prenatal Screening and Diagnosis, Dr Lieve Page-Christiaens and Dr Hanns-Georg Klein have compiled the first authoritative volume on cfDNA NIPT methods and their clinical implementation.

  • Cardiovascular Thrombus

    From Pathology and Clinical Presentations to Imaging, Pharmacotherapy and Interventions
    • 1st Edition
    • On Topaz
    • English
    Cardiovascular Thrombus: From Pathology and Clinical Presentations to Imaging, Pharmacotherapy and Interventions provides a comprehensive, up-to-date presentation of the research and clinical practices as related to the contemporary aspects of the diagnosis and management of cardiovascular thrombosis. The formation, identification and management of cardiovascular thrombus is of paramount importance for researchers and practicing physicians, yet it remains one of the most challenging diagnostic and clinical scenarios. This important reference connects between research, up-to-date clinical knowledge, and the technological tools available for diagnosis and management of thrombus in cardiovascular medicine. The book includes comprehensive descriptions and review of pathology, clinical presentations, diagnosis, pharmacotherapy, interventions and future trends. It is the perfect reference for basic science students and researchers in general and interventional cardiology, general and interventional radiology, vascular medicine specialists, and vascular, general and cardiac surgeons.

  • Analysis of Pesticide in Tea

    Chromatography-Mass Spectrometry Methodology
    • 1st Edition
    • Guo-Fang Pang
    • English
    Analysis of Pesticide in Tea: Chromatography-Mass Spectrometry Methodology is a comprehensive book, providing serial, rapid, high-throughput analytical methods for determining more than 600 pesticides in tea. There are increasing numbers of strict limit standards for pesticide residues in edible agricultural products in countries all over the world. The threshold for pesticide residues in tea is high for international trade. At present, 17 countries and international organizations have stipulated MRL levels for over 800 pesticide residues in tea. All methods described in this book are validated by an independent, U.S.-based organization (AOAC International), and all indexes have satisfied AOAC International's criteria. China has a history of 5000 years in growing tea and is a large tea producer with 80 million people involved in tea growing. China exports tea to over 100 countries worldwide, enjoying a high reputation for quality and variety.

  • Advanced Rehabilitative Technology

    Neural Interfaces and Devices
    • 1st Edition
    • Qingsong Ai + 3 more
    • English
    Advanced Rehabilitative Technology: Neural Interfaces and Devices teaches readers how to acquire and process bio-signals using biosensors and acquisition devices, how to identify the human movement intention and decode the brain signal, how to design physiological and musculoskeletal models and establish the neural interfaces, and how to develop neural devices and control them efficiently using biological signals. The book takes a multidisciplinary theme between the engineering and medical field, including sections on neuromuscular/brain signal processing, human motion and intention recognition, biomechanics modelling and interfaces, and neural devices and control for rehabilitation. Each chapter goes through a detailed description of the bio-mechatronic systems used and then presents implementation and testing tactics. In addition, it details new neural interfaces and devices, some of which have never been published before in any journals or conferences. With this book, readers will quickly get up-to-speed on the most recent and future advancements in bio-mechatronics engineering for applications in rehabilitation.

  • Darwin’s Pangenesis and Its Rediscovery Part B

    • 1st Edition
    • Volume 102
    • Dhavendra Kumar
    • English
    Darwin’s Pangenesis and its Rediscovery Part B explores Darwin's Pangenesis, an expanded cell theory and unified theory of heredity and variation from over 150 years ago that strengthened his theory of evolution and explained many phenomena of life. Now, new discoveries on circulating DNA, mobile RNAs, prions and extracellular vesicles are providing striking evidence for the chemical existence of Darwin’s imaginary gemmules. In addition, new evidence for the inheritance of acquired characters, graft hybridization, and many other phenomena that Pangenesis supposedly explains are progressing, and are hence explored in this comprehensive volume. Specific chapters in this new volume include Darwin and Mendel: The Historical Connection, Darwin’s Pangenesis and Graft Hybridization, Darwin’s Pangenesis and Medical Genetics, Darwin’s Pangenesis and Certain Anomalous Phenomena, and Natural Selection and Pangenesis: The Darwinian Synthesis.

  • Polyphenols in Plants

    Isolation, Purification and Extract Preparation
    • 2nd Edition
    • Ronald Ross Watson
    • English
    Polyphenols in Plants: Isolation, Purification and Extract Preparation, 2nd edition, provides a detailed insight into polyphenols that occur naturally in plants and how they can be affected during growth and development, then effectively removed and optimized for various applications in food production. Historically, plants have been the major sources for drugs and health promotion. While there are a small number of nutrients contained, the growing focus is on the very diverse, complex ring structures: polyphenols that are not nutritious. In order to study or use them in patient treatment, the polyphenols need to be isolated, identified, and purified for application and study. This book brings together experts in the field who share their ongoing examination of isolation and purification of polyphenols as well as determination of their structures and composition. Polyphenols in Plants covers a range of new topics including polyphenols in vegetable waste and agricultural byproducts, extraction methods and characterization of polyphenols, and isolation techniques in the development of new compounds and their use in cancer therapy. This book will be useful to plant scientists and dietary supplement producers, as well as scientists in the food industry and alternative medicine who are interested in the specific health benefits of various dietary extracts and other polyphenol resources.

  • Postharvest Disinfection of Fruits and Vegetables

    • 1st Edition
    • Mohammed Wasim Siddiqui
    • English
    Postharvest Disinfection of Fruits and Vegetables describes available technologies to reduce microbial infection for maintaining postharvest quality and safety. The book analyzes alternative and traditional methodologies and points out the significant advantages and limitations of each technique, thus facilitating both cost and time savings. This reference is for anyone in the fresh produce industry who is involved in postharvest handling and management. It discusses, in detail, the latest disinfection approaches, low-cost treatment strategies, management and protocols to control fresh produce qualities, diseases and insect infestation.

  • Obesity

    Oxidative Stress and Dietary Antioxidants
    • 1st Edition
    • Amelia Marti del Moral + 1 more
    • English
    Obesity: Oxidative Stress and Dietary Antioxidants cover the science of oxidative stress in obesity and associated conditions, including metabolic syndrome, bariatric surgery, and the potentially therapeutic usage of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are not described in isolation, but in concert with other processes, such as apoptosis, cell signaling and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is but a single component. The book is designed for nutritionists, dietitians, food scientists, physicians and clinical workers, health care workers and research scientists.

  • The Teeth of Mammalian Vertebrates

    • 1st Edition
    • Barry Berkovitz + 1 more
    • English
    "The Teeth of Mammalian Vertebrates is an important reference for researchers in dentistry, comparative morphology, anthropology, and vertebrate palaeontology, and those with an interest in exploring and understanding diversity. The book provides a comprehensive and informed analysis of mammalian dentitions and highlights the importance of teeth as drivers and mirrors of evolution and diversity." - Journal of Anatomy The Teeth of Mammalian Vertebrates presents a comprehensive survey of mammalian dentitions that is based on material gathered from museums and research workers from around the world. The teeth are major factors in the success of mammals, and knowledge of tooth form and function is essential in mammalian biology. Illustrated with high-quality color photographs of skulls and dentitions, together with X-rays, CT images and histology, this book reveals the tremendous variety of tooth form and structure in mammals. Written by two internationally-reco... experts in dental anatomy, the book provides an up-to-date account of how teeth are adapted to acquiring and processing food. With its companion volume, this book provides a complete survey of the teeth of vertebrates. It is the ideal resource for students and researchers in zoology, biology, anthropology, archaeology and dentistry.

  • Lentils

    Potential Resources for Enhancing Genetic Gains
    • 1st Edition
    • Mohar Singh
    • English
    Lentils: Potential Resources for Enhancing Genetic Gains describes the evolutionary aspects and agronomic potential of this important pulse with emphasis placed on wide hybridization, including molecular aspects and future breeding strategies. The existing variability among cultivated germplasm has been exploited to reach a desirable level of productivity. However, to attain further breakthroughs in increasing yield and improving stability in future cultivars, new sources of genes/alleles need to be identified and incorporated into cultivated varieties. This book provides specific use information, including wild lentil germplasm utilization, thus allowing for the selection of transgressive interspecific recombinants that can be adapted to specific environments.

  • Principles of Regenerative Medicine

    • 3rd Edition
    • Anthony Atala + 3 more
    • English
    Principles of Regenerative Medicine, Third Edition, details the technologies and advances applied in recent years to strategies for healing and generating tissue. Contributions from a stellar cast of researchers cover the biological and molecular basis of regenerative medicine, highlighting stem cells, wound healing and cell and tissue development. Advances in cell and tissue therapy, including replacement of tissues and organs damaged by disease and previously untreatable conditions, such as diabetes, heart disease, liver disease and renal failure are also incorporated to provide a view to the future and framework for additional studies.

  • Retrovirus-Cell Interactions

    • 1st Edition
    • Leslie Parent
    • English
    Retrovirus-Cell Interactions provides an up-to-date review of the interactions between retroviruses and the cells they infect, offering a comprehensive understanding of how retroviruses hijack cellular factors to facilitate virus replication. Drugs targeting viral enzymes have been developed to treat HIV; the next challenge is to inhibit virus-cell interactions as next generation treatment strategies. Organized according to the retrovirus' replication cycle, this book does not focus exclusively on HIV, but rather includes important findings in other retroviral systems, including animal retroviruses, retrotransposons, and endogenous retroelements to allow broad comparisons on important commonalities and differences.

  • Radical SAM Enzymes

    • 1st Edition
    • Volume 606
    • English
    Radical SAM Enzymes, Volume 606, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on the Characterization of the glycyl radical enzyme choline trimethylamine-lyase and its radical S-adenosylmethionine activating enzyme, Diphathimide biosynthesis, Radical SAM glycyl radical activating enzymes, Radical SAM enzyme BioB in the biosynthesis of biotin, Biogenesis of the PQQ cofactor, Role of MoaAC in the biogenesis of the molybdenum cofactor, Biosynthesis of the nitrogenase cofactor, Bioinformatics of the radical SAM superfamily, The involvement of SAM radical enzymes in the biosynthesis of methanogenic coenzymes, methanopterin and coenzyme F420, and more.

  • Cerebral Lateralization and Cognition: Evolutionary and Developmental Investigations of Behavioral Biases

    • 1st Edition
    • Volume 238
    • English
    Cerebral Lateralization and Cognition: Evolutionary and Developmental Investigations of Motor Biases, Volume 238, the latest release in the Progress in Brain Research series, discusses interdisciplinary research on the influence of cerebral lateralization on cognition within an evolutionary framework. Chapters of note in this release include Evolutionary Perspectives: Visual/Motor Biases and Cognition, Manual laterality and cognition through evolution: An archeological perspective, Laterality in insects, Motor asymmetries in fish, amphibians and reptiles, Visual biases and social cognition in animals, Mother and offspring lateralized social interaction across animal species, Manual bias, personality and cognition in common marmosets and other primates, and more.

  • Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies

    • 1st Edition
    • Sorin Hostiuc
    • English
    Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies offers thorough discussions on preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, sex selection, predictive testing, secondary findings, embryo reduction and the moral status of the embryo, genetic enhancement, and the sharing of genetic data. Chapter contributions from leading bioethicists and clinicians encourage a global, holistic perspective on applied challenges and the moral questions relating the implementation of genetic reproductive technology. The book is an ideal resource for practitioners, regulators, lawmakers, clinical researchers, genetic counselors and graduate and medical students. As the Human Genome Project has triggered a technological revolution that has influenced nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, prenatal genetic testing, and gene therapy, this book presents a timely resource.

  • Neuro-oncology, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 36-3
    • Patrick Y Wen + 1 more
    • English
    This issue of Neurologic Clinics, edited by Drs. Patrick Y. Wen and Eudocia Quant Lee, will focus on Neuro-oncology. Topiocs include, but are not limited to, Epidemiology of brain tumors, Molecular pathogenesis of brain tumors, Changes in WHO classification of brain tumors, Neurologic and medical management of brain tumors, Grade 2 and 3 Gliomas, Glioblastoma, Benign brain tumors, Primary CNS lymphoma and neurologic complications of systemic lymphoma, Pediatric brain tumors, Brain metastases, Metastatic complications of cancer, Neurologic complications of radiation therapy, Neurologic complications of systemic anticancer therapies, Neurocognitive complaints in cancer patients, and Paraneoplastic syndromes.

  • Gunner Goggles Neurology

    • 1st Edition
    • Hao-Hua Wu + 1 more
    • English
    The Gunner Goggles Series is the first exam prep resource written by a high-scoring peer group of medical students, ensuring the most practical and efficient study guidance. It organizes topics around the USMLE and NBME content outlines for the required shelf exams and features state-of-the-art Augmented Reality (AR) mobile application to extend learning beyond the book. This innovative series features AR opportunities throughout the text for an integrated print-mobile experience that maximizes learning and test preparation. The Gunner Goggle function allows you to scan pages for integrated AR links, unlocking animations, visuals, and 3D models that clarify complex anatomy, conditions, and concepts in a remarkably effective and unique manner. Gunner Goggles Series: Neurology is one of seven authoritative exam preparation guides that use cutting-edge AR technology to fully prepare you for the NBME clinical shelf exams, the USMLE Step 2 Clinical Knowledge (CK) exam, and successful clinical rotations.

  • Marine Mammal Ecotoxicology

    Impacts of Multiple Stressors on Population Health
    • 1st Edition
    • Maria Cristina Fossi + 1 more
    • English
    Marine Mammal Ecotoxicology: Impacts of Multiple Stressors on Population Health provides tactics on how to develop a comprehensive methodology for the study of existing threats to marine mammals. By presenting a conservation-biology approach and new and emerging technologies, this work helps provide crucial knowledge on the status of marine mammal populations that not only helps readers understand the ecosystem’s health, but also instigate mitigation measures. This volume provides information that helps investigators unravel the relationships between exposure to environmental stressors (e.g., climate change, pollutants, marine litter, pathogens and biotoxins) and a range of endpoints in marine mammal species. The application of robust examination procedures and biochemical, immunological, and molecular techniques, combined with pathological examination and feeding ecology, has led to the development of health assessment methods at the individual and population levels in wild marine mammals.

  • Polyphenols: Mechanisms of Action in Human Health and Disease

    • 2nd Edition
    • Ronald Ross Watson + 2 more
    • English
    Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products. This very diverse and multi-functional group of active plant compounds contain powerful antioxidant properties and exhibit remarkable chemical, biological and physiological properties, including cancer prevention and cardio-protective activities.

  • Polyphenols: Prevention and Treatment of Human Disease

    • 2nd Edition
    • Ronald Ross Watson + 2 more
    • English
    Polyphenols in Prevention and Treatment of Human Disease, Second Edition authoritatively covers evidence of the powerful health benefits of polyphenols, touching on cardiovascular disease, cancer, obesity, diabetes and osteoporosis. This collection represents the contributions of an international group of experts in polyphenol research who share their expertise in endocrinology, public health, cardiology, pharmacology, agriculture and veterinary science. Researchers from diverse backgrounds will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted insights into the mechanisms of disease. This reference fills a void in research where nutritionists and alternative therapies may be applicable.

  • The Use of Mass Spectrometry Technology (MALDI-TOF) in Clinical Microbiology

    • 1st Edition
    • Fernando Cobo
    • English
    The Use of Mass Spectrometry Technology (MALDI-TOF) in Clinical Microbiology presents the state-of the-art for MALDI-TOF mass spectrometry. It is a key reference defining how MALDI-TOF mass spectrometry is used in clinical settings as a diagnostic tool of microbial identification and characterization that is based on the detection of a mass of molecules. The book provides updated applications of MALDI-TOF techniques in clinical microbiology, presenting the latest information available on a technology that is now used for rapid microbial identification at relatively low cost, thus offering an alternative to conventional laboratory diagnosis and proteomic identification systems. Although the main use of the technology has, until now, been identification or typing of bacteria from a positive culture, applications in the field of virology, mycology, microbacteriology and resistances are opening up new opportunities.

  • Human Genome Informatics

    Translating Genes into Health
    • 1st Edition
    • Christophe Lambert + 2 more
    • English
    Human Genome Informatics: Translating Genes into Health examines the most commonly used electronic tools for translating genomic information into clinically meaningful formats. By analyzing and comparing interpretation methods of whole genome data, the book discusses the possibilities of their application in genomic and translational medicine. Topics such as electronic decision-making tools, translation algorithms, interpretation and translation of whole genome data for rare diseases are thoroughly explored. In addition, discussions of current human genome databases and the possibilities of big data in genomic medicine are presented. With an updated approach on recent techniques and current human genomic databases, the book is a valuable source for students and researchers in genome and medical informatics. It is also ideal for workers in the bioinformatics industry who are interested in recent developments in the field.

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