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Elsevier

Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • The Langevin and Generalised Langevin Approach to the Dynamics of Atomic, Polymeric and Colloidal Systems

    • 1st Edition
    • Ian Snook
    • English
    The Langevin and Generalised Langevin Approach To The Dynamics Of Atomic, Polymeric And Colloidal Systems is concerned with the description of aspects of the theory and use of so-called random processes to describe the properties of atomic, polymeric and colloidal systems in terms of the dynamics of the particles in the system. It provides derivations of the basic equations, the development of numerical schemes to solve them on computers and gives illustrations of application to typical systems.Extensive appendices are given to enable the reader to carry out computations to illustrate many of the points made in the main body of the book.

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 41
    • English
    Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Sections I-IV are disease orientated and generally report on specific medicinal agents. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design. Section VII looks at Trends and Perspectives in the pharmaceuticals market.

  • The Electrochemistry and Characteristics of Embeddable Reference Electrodes for Concrete

    • 1st Edition
    • Volume 43
    • R Myrdal
    • English
    Using reference electrodes to monitor the electrochemical potential of steel reinforcement in concrete is a well established technique for assessing the severity of corrosion and for controlling cathodic protection systems. This report gives a state-of-the-art overview of the electrochemical and physical characteristics and performance of embeddable reference electrodes for concrete, and the method used for installing them.The report first reviews electrochemical potential and reference electrodes in general. It then assesses the different types of reference electrodes for concrete. Finally, it considers key issues such as location and quality control which need to be considered when installing reference electrodes in steel-reinforced concrete structures.

  • The Alkaloids

    Chemistry and Biology
    • 1st Edition
    • Volume 63
    • Geoffrey A. Cordell
    • English
    This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than forty years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids.

  • Coherent Synchronized Oxidation Reactions by Hydrogen Peroxide

    • 1st Edition
    • Tofik M. Nagiev
    • English
    Describes the relations between reactions in chemical and biochemical systems with special emphasis to high selective oxidation reactions by hydrogen peroxide.Outlines possible ways for the application of these reactions in an industrial scale.

  • Elsevier's Dictionary of Chemoetymology

    The Whys and Whences of Chemical Nomenclature and Terminology
    • 1st Edition
    • Alexander Senning
    • English
    Noting a marked lack of comprehensiveness and/or contemporaneity among typical reference works on chemical etymology, as well as a somewhat spotty coverage of chemical terms and their etymology in comprehensive dictionaries and textbooks the author decided to write an up-to-date desk reference on chemical etymology which would satisfy the needs of casual readers as well as those of more demanding users of etymological lore. Characteristic user-friendly features of the present work include avoidance of cumbersome abbreviations, avoidance of entries in foreign alphabets, and a broad coverage of all chemical disciplines including mineralogy. Biological, medical, geological, physical and mathematical terms are only considered where they appear of interest to mainstream chemists.This book does not provide definitions of terms (unless required in the etymological context) nor guidance as to the timeliness of different nomenclature systems. The typical user will from the outset be well aware of the exact meaning of the terms he or she focuses on and only require the etymological background to be used. Examples of sources which have been drawn upon in the preparation of this book, apart from the extremely useful Internet resource Google, are listed, but an exhausting enumeration would be tiresome and impractical..

  • Solution Chemistry

    Minerals and Reagents
    • 1st Edition
    • Volume 17
    • P. Somasundaran + 1 more
    • English
    Surfactants have been used for many industrial processes such as flotation, enhanced oil recovery, soil remediation and cleansing. Flotation technology itself has been used in industry since the end of the 19th century, and even today it is an important method for mineral processing and its application range is expanding to other areas. This technology has been used in the treatment of wastewater, industrial waste materials, separation and recycling of municipal waste, and some unit processes of chemical engineering. The efficiency of all these operations depends primarily on the interactions among surfactants, solids and media. In this book, the fundamentals of solution chemistry of mineral/surfactant systems are discussed, as well as the important calculations involved. The influence of relevant physico-chemical conditions are also presented in detail.

  • The Encyclopedia of Mass Spectrometry

    Volume 8: Hyphenated Methods
    • 1st Edition
    • English
    Volume 8: Hyphenated Methods Starting with gas chromatography–mass spectrometry (GC–MS) and continuing through GCxGC–MS, LC–MSn, and LC–NMR–MS, hyphenated methods have revolutionized chemical analysis. This volume covers that revolution in two parts. The first (Chapters 1–4) describes principles, instrumentation, and technology, and the second (Chapters 5–10) organizes major application areas in GC–MS and LC–MS. After a general introduction (Chapter 1), attention is paid to principles and instrumentation of GC–MS (Chapter 2) and LC–MS (Chapter 3). Other hyphenated methods, including online combinations of capillary electromigration methods and supercritical fluid chromatography with mass spectrometry, are in Chapter 4. Applications are then covered in the remaining chapters. The application-oriented chapters are focused on the role of mainly LC–MS in the pharmaceutical field (Chapter 5) and biochemical and biotechnological applications (Chapter 10), and the application of both GC–MS and LC–MS in relation to environmental analysis (Chapter 6), food safety and food analysis (Chapter 7), characterization of natural products (Chapter 8), and clinical, toxicological, and forensic analysis (Chapter 9).

  • Interface Science in Drinking Water Treatment

    Theory and Applications
    • 1st Edition
    • Volume 10
    • Gayle Newcombe + 1 more
    • English
    It is difficult to imagine anything more important to the human population than safe drinking water. Lack of clean drinking water is still the major cause of illness and death in young children in developing countries. In more fortunate communities, where water treatment is practiced, the primary aim of water authorities is to provide water that is free from pathogens and toxins. Most countries now have water quality regulations, or guidelines, which are driving water authorities to produce purer water, with the minimum of contamination from natural or man-made origin. At the same time, consumers are demanding that chemicals added during the treatment of drinking water be kept to a minimum. As a consequence, conventional clarification methods are being challenged to comply with the new regulations and restrictions and our understanding of the mechanisms involved is being tested as never before. Interface Science in Drinking Water Treatment contains a rigorous review of water treatment practices from a fundamental viewpoint. The book includes material from leading experts in the field of water treatment, reviewing their specific fields of expertise against a background of colloid and surface chemistry, and examines each step of the journey from source to consumer tap. It therefore permits the reader to develop a deep understanding of the complex processes taking place and of the necessary treatments which are vital for the provision of safe and palatable drinking water. The book is aimed at researchers, educators and practitioners in science and engineering, particularly those involved in water treatment and colloidal chemistry.

  • Handbook of Adhesives and Sealants

    General Knowledge, Application of Adhesives, New Curing Techniques
    • 1st Edition
    • Volume 2
    • Philippe Cognard
    • English
    Contributions from more than 60 authors, each a well-known specialist in their field, have been co-ordinated to produce the most comprehensive Handbook of Adhesives and Sealants ever published. The handbook will be published as 8 volumes, over a period of 4 years and will contain over 2800 pages, rich with case studies, industrial applications and the latest research. It is a work in progress, enabling the latest new and important applications to be included as they happen. Volume 2 of Elsevier’s Handbook of Adhesives & Sealants Series, General knowledge, application of adhesives & new curing techniques, covers the mechanisms of adhesion, its application, and drying and curing techniques. The volume is divided in to the following sections: • Theory of adhesion • Metering and dispensing • Design and calculation of bonded joints• Heat stable adhesives• UV curing • Flexible bonding and sealants Each contributing author is a scientist, practitioner, engineer, or chemist with an abundance of practical experience in their respective field, making this text an authoritative reference source for any materials scientist or engineer, whether in academia or industry.

  • Chemistry and Application of H-Phosphonates

    • 1st Edition
    • Kolio D. Troev
    • English
    Chemistry and Application of H-Phosphonates is an excellent source for those planning the synthesis of new phosphorus-containin... compounds and in particular derivatives containing a phosphonate, phosphoramide or phosphonic acid diester group. The rich chemistry, low cost and easy availability of diesters of H-phosphonic acid makes them an excellent choice as synthone in a number of practically important reactions. Phosphonic acid esters are intermediates in the synthesis of important classes of compounds such as alpha-aminophosphoni... acids, bisphosphonates, epoxyalkylphosphonat... alpha-hydroxyalkylph... phosphoramides, poly(alkylene H-phosphonate)s, poly(alkylene phosphate)s, nucleoside H-phosphonates. The synthesis of each of these compound classes is reviewed in detail.Alpha-Aminoph... acids are an important class of biologically active compounds, which have received an increasing amount of attention because they are considered to be structural analogues of the corresponding Alpha-amino acids. The utilities of alpha-aminophosphona... as peptide mimics, haptens of catalytic antibodies, enzyme inhibitors, inhibitors of cancers, tumours, viruses, antibiotics and pharmacologic agents are well documented. Alpha-Hydroxyalkanep... are compounds of significant biological and medicinal applications. Dialkyl epoxyalkylphosphonat... are of interest because of their use as intermediates in the synthesis of bioactive substances, and as modifiers of natural and synthetic polymers. Bisphosphonates are drugs that have been widely used in different bone diseases, and have recently been used successfully against many parasites. Poly(alkylene H-phosphonate)s and poly(alkylene phosphate)s are promising, biodegradable, water soluble, new polymer-carriers of drugs. Nucleoside H-phosphonates seem to be the most attractive candidates as starting materials in the chemical synthesis of DNA and RNA fragments. The 5’-hydrogen phosphonate-3’-azido... is one of the most significant anti-HIV prodrug, which is currently in clinical trials.Chapters review the synthesis; physical and spectral properties (1H, 13C, 31P and 17O NMR data); characteristic reactions; important classes of compounds based on these esters of H-phosphonic acid; their application as physiologically active substances, flame retardants, catalysts, heat and light stabilizers, lubricants, scale inhibitors, polymer-carriers of drugs; preparation of H-phosphonate diesters and general procedures for conducting the most important reactions.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 91
    • Alan R. Katritzky
    • English
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area - one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 58
    • Graham A. Webb
    • English
    Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has grown to such importance as NMR spectroscopy. It is used in all branches of science where precise structural determination is required and where the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy.

  • Pharmaceutical Manufacturing Encyclopedia, 3rd Edition Database

    • 3rd Edition
    • William Andrew William Andrew Publishing
    • English
    This industry standard database on pharmaceutical manufacturing processes has been completely updated to include FDA drugs approved up to the summer of 2004. The database gives details for the manufacture of 2226 pharmaceuticals that are being marketed as a trade-named product somewhere in the world. Each entry includes:ò Therapeutic function ò Chemical and common nameò Structural Formulaò Chemical Abstracts Registry no.ò Trade name, manufacturer, country, and year introducedò Raw Materialsò Manufacturing ProcessIn addition, references are also cited under each drug's entry to major pharmaceutical works where additional information can be obtained on synthesis and the pharmacology of the individual products. The database is for the Windows OS.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 57
    • Graham A. Webb
    • English
    Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has grown to such importance as NMR spectroscopy. It is used in all branches of science where precise structural determination is required and where the nature of interactions and reactions in solution is being studied. Annual Reports on NMR has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy.

  • Studies in Natural Products Chemistry

    Bioactive Natural Products (Part M)
    • 1st Edition
    • Volume 33
    • Atta-ur Rahman
    • English
    Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry.The present volume contains 22 articles written by leading experts in natural product chemistry on biologically active natural products. It includes research on a variety of different classes of natural products including sesquiterpenes, quassinoids, diterpenoids, lignans, oligostilbenes, phenylethanoids, phenylpropanoid glycosides, curcumin analogues, glycosphingolipids etc. Many of these have been found to be active in a number of different disease conditions.

  • Crystallography Made Crystal Clear

    A Guide for Users of Macromolecular Models
    • 3rd Edition
    • Gale Rhodes
    • English
    Crystallography Made Crystal Clear makes crystallography accessible to readers who have no prior knowledge of the field or its mathematical basis. This is the most comprehensive and concise reference for beginning Macromolecular crystallographers, written by a leading expert in the field. Rhodes' uses visual and geometric models to help readers understand the mathematics that form the basis of x-ray crystallography. He has invested a great deal of time and effort on World Wide Web tools for users of models, including beginning-level tutorials in molecular modeling on personal computers. Rhodes' personal CMCC Home Page also provides access to tools and links to resources discussed in the text. Most significantly, the final chapter introduces the reader to macromolecular modeling on personal computers-featuring SwissPdbViewer, a free, powerful modeling program now available for PC, Power Macintosh, and Unix computers. This updated and expanded new edition uses attractive four-color art, web tool access for further study, and concise language to explain the basis of X-ray crystallography, increasingly vital in today's research labs.

  • Fundamentals of Preparative and Nonlinear Chromatography

    • 2nd Edition
    • Georges Guiochon + 2 more
    • English
    Fundamentals of Preparative and Nonlinear Chromatography, Second Edition is devoted to the fundamentals of a new process of purification or extraction of chemicals or proteins widely used in the pharmaceutical industry and in preparative chromatography. This process permits the preparation of extremely pure compounds satisfying the requests of the US Food and Drug Administration. The book describes the fundamentals of thermodynamics, mass transfer kinetics, and flow through porous media that are relevant to chromatography. It presents the models used in chromatography and their solutions, discusses the applications made, describes the different processes used, their numerous applications, and the methods of optimization of the experimental conditions of this process.

  • Statistical Design - Chemometrics

    • 1st Edition
    • Volume 25
    • Roy E Bruns + 2 more
    • English
    Statistical Design-Chemometrics is applicable to researchers and professionals who wish to perform experiments in chemometrics and carry out analysis of the data in the most efficient way possible. The language is clear, direct and oriented towards real applications. The book provides 106 exercises with answers to accompany the study of theoretical principles. Forty two cases studies with real data are presented showing designs and the complete statistical analyses for problems in the areas chromatography, electroanalytical and electrochemistry, calibration, polymers, gas adsorption, semiconductors, food technology, biotechnology, photochemistry, catalysis, detergents and ceramics. These studies serve as a guide that the reader can use to perform correct data analyses.

  • Advances in Quantum Chemistry

    • 1st Edition
    • Volume 49
    • John R. Sabin + 1 more
    • English
    Advances in Quantum Chemistry presents surveys of current developments in this rapidly developing field that falls between the historically established areas of mathematics, physics, chemistry, and biology. With invited reviews written by leading international researchers, each presenting new results, it provides a single vehicle for following progress in this interdisciplinary area. This volume continues the tradition with high quality and thorough reviews of various aspects of quantum chemistry. It contains a variety of topics that include an extended and in depth discussion on the calculation of analytical first derivatives of the energy in a similarity transformed equation of motion couples cluster method.

  • Profiles of Drug Substances, Excipients and Related Methodology

    • 1st Edition
    • Volume 32
    • Harry G. Brittain
    • English
    Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions are now augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change meets the needs of the pharmaceutical community and allows the development of a timely vehicle for publishing review materials on this topic. While offering comprehensive and specialised chapters, Profiles of Drug Substances, Excipients and Related Methodology, Volume 32 also presents a methodology review article on the validation of chromatographic methods of analysis, as well as a summary of the publications in 2004 that dealt with polymorphism and solvatomorphism.

  • Chemistry and Biology of Heparin and Heparan Sulfate

    • 1st Edition
    • Hari G. Garg + 2 more
    • English
    The chemistry, biochemistry and pharmacology of heparin and heparan sulfate have been and continue to be a major scientific undertaking - heparin and its derivative remain important drugs in clinical practice. Chemistry and Biology of Heparin and Heparan Sulfate provides readers with an insight into the chemistry, biology and clinical applications of heparin and heparan sulfate and examines their function in various physiological and pathological conditions. Providing a wealth of useful information, no other tome covers the diversity of topics in the field. Students, doctors, chemists, biochemists, and research scientists will find this book an invaluable source for updating their current knowledge of developments in this area.

  • Landmark Papers in Clinical Chemistry

    • 1st Edition
    • Richard M. Rocco
    • English
    This is the first major review of the developments in clinical laboratory science in the 20th century presented in the words of the original inventors and discoverers. Introductory comments by the editor help place the works within the historical context.Landmark Papers addresses:*The origin of the home pregnancy test available today in every drugstore*The woman who invented a billion dollar technology, refused to patent it and went on to win a Nobel Prize*The scientists who worked on the US Government’s crash program at the start of WWII to find a substitute for the malaria drug quinine*The blood test used to monitor the effectiveness of cholesterol lowering drugs that today are taken by over 20 million patients*The graduate student who invented a technology for testing for infectious diseases, took it to Africa to screen people for malaria for the first time and which is now used to test for HIV infection world-wide*The invention of molecular diagnostics by Linus Pauling and the road to individualized medicine*The development of the glucose meter used by diabetics up to six times a day to monitor their metabolic control

  • The Encyclopedia of Mass Spectrometry

    Volume 3: Biological Applications Part B
    • 1st Edition
    • Richard Caprioli
    • English
    Volume 3 looks at classes of biomolecules including carbohydrates, nucleic acids, and lipids. In addition, special areas of application are included, such as pharmaceuticals, natural products, isotope ratio methods for biomolecules analysis, and clinical applications. The articles are arranged under general headings for continuity and ease of access, although several of these are of interest across the various disciplines. The articles are intended to teach and therefore strive to cover basics and sufficient additional detail to bring the reader up-to-date on a given subject. Some advanced topics are also covered, either in a special section of articles or in additional reading citations.

  • Quantum Chemistry

    • 3rd Edition
    • John P. Lowe + 1 more
    • English
    Lowe's new edition assumes little mathematical or physical sophistication and emphasizes an understanding of the techniques and results of quantum chemistry. It can serve as a primary text in quantum chemistry courses, and enables students and researchers to comprehend the current literature. This third edition has been thoroughly updated and includes numerous new exercises to facilitate self-study and solutions to selected exercises.

  • Contemporary Aspects of Boron: Chemistry and Biological Applications

    • 1st Edition
    • Volume 22
    • Hijazi Abu Ali + 2 more
    • English
    Contemporary Aspects of Boron: Chemistry and Biological Applications highlights the biological activity and applications of boron containing compounds. The authors’ specific approach surveys general features of the subject, while exploring new and novel strategies for preparing certain chemical and natural boron products that are of significant substance in medicinal chemistry. For example, cancer treatment is one of the most important issues related to such products. In addition to contributing to the development of new drugs by addressing biological applications in medicinal and industrial fields, the book provides a comprehensive review of the most relevant components that comprise the pharmaceutical, medicinal and environmental applications of boron containing compounds.

  • Handbook of Adhesives and Sealants

    Basic Concepts and High Tech Bonding
    • 1st Edition
    • Volume 1
    • Philippe Cognard
    • English
    Handbook of Adhesives and Sealants is the most comprehensive Adhesives and Sealants Handbook ever published, with the cooperation of around 35 authors from all over the world – each one a specialist in their field. It will include 80 chapters dealing with general information, theory of bonding and sealing, design of bonding parts, technical characteristics, chemistry, types of adhesives, application, equipment, controls, standards etc. Industrial applications such as automotive, aeronautics, building and civil engineering, electronics, packaging, wood, furniture, metals, plastics and composites, textiles, footwear etc.

  • Strategies and Tactics in Organic Synthesis

    • 1st Edition
    • Volume 6
    • Michael Harmata
    • English
    A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project. In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world.

  • Strategic Applications of Named Reactions in Organic Synthesis

    • 1st Edition
    • Laszlo Kurti + 1 more
    • English
    Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist.

  • Special Distillation Processes

    • 1st Edition
    • Zhigang Lei + 2 more
    • English
    Special distillation processes are required for separation of mixtures close to boiling point or for forming azeotrope mixtures into their pure components. In Special Distillation Processes, the authors focus on latest developments in the field, such as separation methods that may prove useful for solving problems encountered during research. Topics include extraction, membrane and adsorption distillation involving the separation principle, process design and experimental techniques. The relationship between the processes and the techniques are also presented. Comprehensive and easy-to-read, this book provides key information needed to understand the processes and is a valuable reference source for chemical engineers as well as students wishing to branch out in chemical engineering.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 54
    • Graham A. Webb
    • English
    Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has grown to such importance as NMR spectroscopy. It is used in all branches of science where precise structural determination is required and where the nature of interactions and reactions in solution is being studied. Annual Reports on NMR has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy.

  • Analytical Pyrolysis of Synthetic Organic Polymers

    • 1st Edition
    • Volume 25
    • Serban C. Moldoveanu
    • English
    Analytical Pyrolysis of Synthetic Organic Polymers is a follow-up to Analytical Pyrolysis of Natural Organic Polymers, which is volume 20 of the series. The main focus of the book is on practical applications of analytical pyrolysis in synthetic organic polymer identification and characterization. The first part of the book has five chapters including an introduction, a discussion on physico-chemistry of thermal degradation of synthetic polymers and on instrumentation used in analytical pyrolysis, a chapter discussing what type of information can be obtained from analytical pyrolysis, and a chapter dedicated to the analysis and characterization of synthetic polymers.The second part systematically covers the analytical pyrolysis of various classes of synthetic polymers. Some theoretical background for the understanding of polymer structure using analytical pyrolysis is also discussed.

  • Profiles of Drug Substances, Excipients and Related Methodology

    • 1st Edition
    • Volume 31
    • Harry G. Brittain
    • English
    Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions will now also be augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change is required to better meet the needs of the pharmaceutical communtiy and to allow the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series will encompass review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodologoy related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

  • Encyclopedia of Analytical Science

    • 2nd Edition
    • Paul J. Worsfold + 2 more
    • English
    As with the first edition of the Encyclopedia of Analytical Science, Second Edition is designed to provide a detailed and comprehensive publication covering all facets of the science and practice of analysis. The new work has been extensively revised in terms of the titles and content of the first edition, and includes comprehensive coverage of techniques used for the determination of specific elements, compounds and groups of compounds, in physical or biological matrices. It addresses applications of chemical analysis in all areas, ranging from such topics as medicine to environmental science, and geology to food science. Important characterisation techniques, such as microscopy and surface analysis are also included. The complete work consists of around 610 articles, each consisting of about 4000 words, figures and summary tables. These articles are combined to form larger entries providing comprehensive coverage of important topics and assisting the reader in locating material of interest. The entries are arranged in an A to Z format providing a final publication of about two and a half million words in ten volumes. The articles are structured to allow easy access to information on specific analytes, instrumental techniques and sample matrices. There is extensive cross-referencing throughout the Encyclopedia and a detailed index. Also available online via ScienceDirect – featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedire...

  • The Encyclopedia of Mass Spectrometry

    Volume 4: Fundamentals of and Applications to Organic (and Organometallic) Compounds
    • 1st Edition
    • Nico Nibbering
    • English
    Volume 4: Organic and Organometallic Compounds presents a cross section of applications in organic and organometallic chemistry in two parts. Chapters 1 to 6 are devoted to the fundamentals whereas chapters 7 and 8 cover applications to organic and organometallic compounds, either available as pure compounds or present in complex mixtures. Chapter 1 describes the theory for organic mass spectrometry, building on and complementing material in Volume 1. The themes for Chapter 2 are the structures and properties of gas-phase ions of conventional, distonic, and non-covalent complexes. Chapter 3 covers methodology used in study of gas-phase ions. Chapters 4 and 5 turn to mechanisms of both unimolecular and bimolecular reactions of ions and include topics in stereochemistry and radical chemistry. Chapter 6 contains a number of articles on the formation and reactivity of metal ion complexes and organometallic cations and anions, drawing connections with molecular recognition, catalysis and organic synthesis. Chapter 7 deals with the structure determination of organic compounds, including chiral compounds and natural products. In chapter 8 are contributions that provide illustrative examples of the determination of organic compounds present at low levels in complex samples that originate from various natural and biological sources. Included is an article on the determination of explosives.

  • Nitrosation Reactions and the Chemistry of Nitric Oxide

    • 1st Edition
    • D.L.H. Williams
    • English
    Since 1988, there has been much literature published on the chemistry of nitric oxide, particularly in the field of S-nitrosation and the chemistry of S-nitroso compounds. Written by a chemist for the chemistry community, this book provides an update of the chemistry of nitrosation reactions, dealing with both the synthetic and mechanistic aspects of these reactions. It also looks at the chemistry of nitric oxide in relation to the amazing biological properties of this simple diatomic molecule, which were unknown until around 1990.

  • The Encyclopedia of Mass Spectrometry

    Volume 2: Biological Applications Part A
    • 1st Edition
    • Richard Caprioli + 1 more
    • English
    The focus of Volume 2 of the Encyclopedia of Mass Spectrometry is on peptides and proteins, separation techniques, preparation protocols, and the fundamental characteristics as ionic gas phase species that lie within the breadth of the field of mass spectrometry. This volume is divided into four sections; experimental approaches and protocols, sequence analysis, other structural analyses, and targeted applications.

  • Molecular Diversity and Combinatorial Chemistry

    Principles and Applications
    • 1st Edition
    • Volume 24
    • Michael C. Pirrung
    • English
    The field of combinatorial chemistry has seen tremendous growth over the past decade, with a prominence that suggests it will have a continuing impact. Volume 24 in the Tetrahedron Organic Chemistry Series represents new approaches to solving problems in chemical reactivity and function. Molecular Diversity and Combinatorial Chemistry emphasises principles and exemplifies these with examples drawn from recent literature and thus is an excellent guide to the conceptual framework of the field. The textbook includes exercises and worked problems which can provide more independent learning experiences and can also be used by an instructor leading a class on this topic. This volume has been written with the advanced undergraduate and graduate student in mind.

  • Molecular Diversity and Combinatorial Chemistry

    Principles and Applications
    • 1st Edition
    • Volume 24
    • Michael C. Pirrung
    • English
    The field of combinatorial chemistry has seen tremendous growth over the past decade, with a prominence that suggests it will have a continuing impact. Volume 24 in the Tetrahedron Organic Chemistry Series represents new approaches to solving problems in chemical reactivity and function. Molecular Diversity and Combinatorial Chemistry emphasises principles and exemplifies these with examples drawn from recent literature and thus is an excellent guide to the conceptual framework of the field. The textbook includes exercises and worked problems which can provide more independent learning experiences and can also be used by an instructor leading a class on this topic. This volume has been written with the advanced undergraduate and graduate student in mind.

  • Strategies and Tactics in Organic Synthesis

    • 1st Edition
    • Volume 5
    • Michael Harmata
    • English
    A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project. In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world.

  • Secondary Metabolism in Model Systems

    Recent Advances in Phytochemistry
    • 1st Edition
    • Volume 38
    • John Romeo
    • English
    The chapters presented in Secondary Metabolism in Model Systems are a microcosm of what the recent completion, or near completion, of various genome projects are enabling biochemists to understand not only about control and regulation of secondary metabolism, and how various pathways relate to each other, but also about its relation to primary metabolism. A major paradigm shift is occurring in the way researchers need to view "secondary" metabolism in the future.It is also clear that model systems, such as the ones discussed in the symposium, are providing new information and insight almost faster than researchers can process it! The volumes in this series contain articles on developing topics of interest to scientists, students and individuals interested in recent developments in the biochemistry, chemistry and molecular biology of plants.

  • Supercritical Fluids as Solvents and Reaction Media

    • 1st Edition
    • Gerd H. Brunner
    • English
    Supercritical fluids behave either like a gas or a liquid, depending on the values of thermodynamic properties. This tuning of properties, and other advantageous properties of supercritical fluids led to innovative technologies. More than 100 plants of production size are now in operation worldwide in the areas of process and production technology, environmental applications, and particle engineering. New processes are under research and development in various fields. This book provides an overview of the research activities in the field of Supercritical Fluids in Germany. It is based on the research program "Supercritical fluids as solvents and reaction media" on the initiative of the "GVC-Fachausschuß Hochdruckverfahrenst... (i.e. the German working party on High Pressure Chemical Engineering of the Society of Chemical Engineers).This research program provided an immensely valuable platform for exchange of knowledge and experience. More than 50 young researchers were involved contributing with their expertise, their new ideas, and the motivation of youth. The results of this innovative research are described in this book.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 51
    • English
    Almost all branches of chemistry and material science now interface with organometallic chemistry - the study of compounds containing carbon-metal bonds. This widely acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964.

  • Strategies and Tactics in Organic Synthesis

    • 1st Edition
    • Volume 4
    • Michael Harmata
    • English
    A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project. In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world.

  • The Role of Chemistry in the Evolution of Molecular Medicine

    • 1st Edition
    • Imre Csizmadia + 2 more
    • English
    This volume entitled 'The Role of Chemistry in the Evolution of Molecular Medicine' contains a collection of papers that form the proceedings of the Symposium held at the University of Szeged (27-29 June 2003). As well as covering developments in the field over the last 60 years, the proceedings of this Symposium has laid the foundations for the future of the field of molecular medicine. Contributors span a wide range of molecular science disciplines including mathematics, physics, computer science, chemistry, biochemistry, biology and medicine, and cover the whole territory in agreement with the legacy of Professor Albert Szent-Györgyi. This volume was particularly inspired by the booklet published in 1960 by Albert Szent-Györgyi under the title 'Introduction to submolecular biology', and the contents of this booklet have been included here in its entirety as an Appendix.

  • Proteome Analysis

    Interpreting the Genome
    • 1st Edition
    • David W Speicher
    • English
    This book explores the current status of proteomics, an exciting new discipline, which is less than 10 years old. This new field has rapidly grown into a major commercial and research enterprise with great prospects for dramatically advancing our knowledge of basic biological and disease processes. The contributors to this book are an international panel of proteomics experts, who review and discuss the current status of specific technologies and approaches. Proteomics represents an exciting new way to pursue biological and biomedical science at an unprecedented pace. Proteomics takes a broad, comprehensive, systematic approach to understanding biology that is generally unbiased and not dependent upon existing knowledge. The major components of proteomics from basic discovery using a range of alternative analytical methods to discovery validation and use for clinical applications are discussed. State-of-the-art protein profiling methods include high resolution two-dimensional gels, two-dimensional differential in-gel electrophoresis, LC-MS and LC-MS/MS using accurate mass tags, and protein identifications of proteins from gels using mass spectrometry methods are discussed in depth. Other chapters describe comprehensive characterization of proteomes using electrophoretic prefractionation and analyses of sub-proteomes based on specific posttranslational modifications including the phospho-proteome, the glyco-proteome, and nitrated proteins. These conventional proteome analysis chapters are complemented by discussion of emerging technologies and approaches such as affinity based biosensor proteomics as well as the use of protein microarrays, microfluidics and nanotechnology. Strategies for improving throughput by automation are also discussed. Additional chapters address the application of current proteome techniques to clinical problems and the availability of protein expression library resources for proteome studies.

  • Hydrocarbon Thermal Isomerizations

    • 2nd Edition
    • Joseph J. Gajewski
    • English
    Hydrocarbon Thermal Isomerizations summarizes rearrangements which are induced by heating neutral hydrocarbons under non-catalytic conditions in the vapor phase or in non-polar solution. This subject has attracted the interest of mechanistic organic chemists and theorists in the last quarter century because it is one of the few fields workable by state of the art techniques of both camps. This work collects together most of the crucial rate and stereochemical data in a single volume, along with a critical analysis of each of these reactions. Unlike reviews or other books in this area that focus on reaction types, e.g.. electrocyclic reactions, or Claisen rearrangements, this volume is organized like the Chemical Abstracts Formula Index, but with an important exception: all of the relevant derivatives of each parent compound are discussed with the parent and not in their logical formula index positions. As it is not always obvious what is a parent material and what is a derivative, detailed cross-references are included throughout. An important aspect of this edition is the inclusion of calculational results that provide insight, often more than was anticipated, into these relatively simple reactions.

  • Valve-Regulated Lead-Acid Batteries

    • 1st Edition
    • Patrick T. Moseley + 3 more
    • English
    For many decades, the lead-acid battery has been the most widely used energy-storage device for medium- and large-scale applications (approximately 100Wh and above). In recent years, the traditional, flooded design of the battery has begun to be replaced by an alternative design. This version - the valve-regulated lead-acid (VRLA) battery - requires no replenishment of the water content of the electrolyte solution, does not spill liquids, and can be used in any desired orientation. Since the VRLA battery operates in a somewhat different manner from its flooded counterpart, considerable technological development has been necessary to meet the exacting performance requirements of the full range of applications in which rechargeable batteries are used. The valve-regulated design is now well established in the industrial battery sector, and also appears set to be adopted widely for automotive duty. This book provides a comprehensive account of VRLA technology and its uses. In the future, all industrial processes - including the manufacture of batteries - will be required to conform to the conventions of sustainability. Accordingly, the crucial areas of the environmental impact associated with the production and use of VRLA batteries and the recycling of spent units are also treated thoroughly. Valve-Regulated Lead-Acid Batteries gives an essential insight into the science that underlies the development and operation of VRLA batteries and is a comprehensive reference source for those involved in the practical use of the technology in key energy-storage applications.

  • Electrochemistry in Molecular and Microscopic Dimensions

    Proceedings of the 53rd Annual Meeting of the International Society of Elctrochemistry jointly organized with GDCh-Fachgruppe Angewandte Electrochemie, Düsseldorf, Germany, 15-20 September 2002
    • 1st Edition
    • Joachim W. Schultze + 1 more
    • English
    This book is a hard bound edition of a special issue (vol. 48/20-22) of the journal Electrochimica Acta. It summarizes the highlights of the 53rd Annual meeting of the International Society of Electrochemistry and Annual meeting of the GDCh-Fachgruppe Angewandte Elektrochemie. The theme of the conference was Electrochemistry in Molecular and Microscopic dimensions and was based on the role of electrochemistry in the miniaturization of chemical and physical methods. Topics covered are : - development of electrochemistry with microscopic and molecular resolution;- initiation of advances in Electrochemical Microsystem Technologies EMT, and micro/nano-electroni... development of Electrochemical Materials Science for nanomaterials;- enhancement of miniaturization and sensitivity of electroanalysis, and;- the bridge from electrochemistry to biology and medicine of microscopic and molecular understanding.

  • Best Synthetic Methods: Acetylenes, Allenes and Cumulenes

    • 1st Edition
    • Lambert Brandsma
    • English
    There is a vast and often bewildering array of synthetic methods and reagents available to organic chemists today. The Best Synthetic Methods series allows any scientist who is interested in the chemical transformations of molecules to choose between all the alternatives and assess their real advantages and limitations. With the emphasis on laboratory use, these volumes represent a comprehensive and practical guide to modern synthetic organic chemistry. Best Synthetic Methods: Acetylenes, Allenes and Cumulenes is the product of the author's many years practical experience and reading of the original literature. It contains a valuable distillation and critical evaluation of the Best Synthetic Methods for the formation and reaction of molecules containing carbon-carbon triple bonds or cumulative carbon-carbon double bonds. A brief review of each area is provided, but the emphasis in all cases is on describing efficient practical methods to effect the transformations described. The reader can therefore use this book to rapidly review and select the best methods of performing a synthetic conversion to create or modify a molecule containing an acetylene, allene or cumulene functionality. In addition, the documentation of a large number of experimental recipes enables the user to synthesise an unsaturated molecule without the need to access to the original literature.

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