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Books in Life sciences

  • Lysosomal Pathophysiology of Parkinson’s Disease

    • 1st Edition
    • Mattia Volta + 1 more
    • English
    Lysosomal Pathophysiology of Parkinson’s Disease delves into the genetic and genomic revelations that have transformed our understanding of Parkinson’s Disease at the molecular level. The book highlights the critical role of the autophagy-lysosome pathway in the disease's pathogenic processes, drawing a comprehensive timeline of disease onset and progression. It offers a detailed examination of how disruptions in this pathway contribute to the hallmarks of Parkinson’s Disease, providing invaluable insights for researchers and clinicians alike. Subsequent chapters extend these insights by comparing Parkinson’s Disease to other neurodegenerative disorders such as Alzheimer’s Disease and Frontotemporal Dementia. By exploring protein pathology and synaptic alterations, the book underscores the broader implications of autophagy-lysosome dysfunction. Additionally, it discusses how the molecular perspectives gleaned from Parkinson’s Disease can inform our understanding of these other conditions, presenting a unified approach to studying neurodegeneration.
  • Alternative Splicing

    Recent Advances in Health and Disease
    • 1st Edition
    • Sayeed ur Rehman A. Kalam + 1 more
    • English
    Alternative Splicing: Recent Advances in Health and Disease offers a comprehensive study of this cellular process, its fundamental characteristics, latest advances and clinical utilization. Opening with an introduction to alternative splicing and its function in generating transcriptome and protein diversity, the book considers the role of this process across a range of diseases and disorders, including cardiovascular disease, cancer, obesity, and viral infections. Key methods used to study alternative splicing are also investigated, including high-throughput sequencing-based methods, bioinformatics tools, computational methods, single-cell sequencing techniques and mass-spectrometry based proteomics. This is followed with analysis of therapeutic approaches associated with alternative splicing. This is an ideal reference for those involved in investigating alternative splicing and its impact to health and disease, and is therefore relevant to researchers across cell biology, molecular biology, pharmacology and related areas.
  • Gestational Diabetes Mellitus

    Epidemiology, Clinical Practice and Evidence-Based Guidelines
    • 1st Edition
    • Moshe Hod + 6 more
    • English
    Gestational Diabetes Mellitus: Epidemiology, Clinical Practice and Evidence-Based Guidelines is an invaluable resource for healthcare professionals seeking to understand the latest developments in GDM. Over the past 20 years, significant progress has been made in the study of its epidemiology, mechanisms, diagnosis, management, and prevention. This book delves into these advancements, offering insights that are crucial for both researchers and clinicians. It explores potential therapeutic solutions to enhance patient care, and is essential reading for obstetricians, endocrinologists, diabetes researchers, maternal health specialists, and pediatric endocrinologists, as well as specialty fellows, residents, postdoctoral fellows, and graduate students in these fields.
  • Nanomaterials for Stem Cell Modulation

    Innovation and Clinical Applications
    • 1st Edition
    • Syed Mahmood + 3 more
    • English
    Nanomaterials for Stem Cell Modulation: Innovation and Clinical Applications provides a comprehensive exploration of how nanotechnology is transforming stem cell science and regenerative medicine. This authoritative volume examines the physicochemical properties of nanomaterials, their interactions with stem cells, and their capacity to direct stem cell behaviors such as proliferation, differentiation, and therapeutic delivery. By blending foundational principles with cutting-edge innovations, the book bridges the gap between basic laboratory discoveries and clinical translation. Written by experts in the field, the book addresses the critical need for an integrated resource that unifies current knowledge with emerging research and practical applications. While interest in nanotechnology and stem cells continues to grow, the literature remains fragmented. This book fills that gap by offering structured insights, case studies, and guidance on selecting nanomaterial systems tailored to specific therapeutic goals, while also navigating regulatory and translational challenges. Designed for researchers, graduate students, and professionals, the text serves as both a practical guide and an academic reference across disciplines including nanotechnology, stem cell biology, regenerative medicine, tissue engineering, biomedical engineering, and pharmaceutical sciences. It is equally valuable for industry scientists and clinical researchers seeking to develop advanced nanomaterial-based therapies. With its interdisciplinary approach, Nanomaterials for Stem Cell Modulation empowers readers to understand fundamental mechanisms, explore current innovations, and apply nanotechnology-drive... strategies to solve complex healthcare challenges, making it an essential resource for advancing the future of regenerative medicine.
  • Trauma During Pregnancy

    • 1st Edition
    • Jorge Hidalgo + 2 more
    • English
    Trauma During Pregnancy is a volume in the Critical Care Obstetrics series. It’s a novel reference to educate physicians, nurses, and all allied healthcare personnel caring for pregnant women experiencing trauma. The authors offer best practices and evidence-based material explicitly focused on the most common complications in pregnant patients that may occur to improve patient care. It not only covers critical care investigation from medical-surgical complications that any patient can present, but also how to prepare and anticipate complications in the critical care unit.
  • Capsule Endoscopy in Pediatric Patients from Theory to Practice

    • 1st Edition
    • Thomas M. Attard
    • English
    Capsule Endoscopy in Pediatric Patients from Theory to Practice is a practical and authoritative guide that empowers pediatric gastroenterologists, physicians, and trainees to navigate the complexities of Video Capsule Endoscopy (VCE) in children. With a focus on bridging knowledge gaps and providing practical insights, this book offers updated information on understanding and utilizing VCE in the pediatric population. The book covers the background and technical aspects of VCE, including guidance on setting up a pediatric VCE service and an overview of indications and limitations. It delves into practical aspects such as preprocedural preparation, artifact reduction techniques, and management of capsule retention. By exploring VCE in various disease conditions such as inflammatory bowel disease, gastrointestinal bleeding, hereditary polyposis syndromes, and chronic abdominal pain, readers gain a comprehensive understanding of diagnosis, surveillance, and management. Special content elements, including key terms, case studies, and a timeline of recent advances, enhance the learning experience. This essential resource empowers readers to optimize patient care, make informed decisions, and confidently navigate the realm of VCE in children.
  • Sleep Neurology

    • 1st Edition
    • Anne Marie Morse
    • English
    Sleep Neurology explores the intricate relationship between sleep and neurological health, bridging the gap between theoretical knowledge and practical application. This comprehensive reference highlights the role of sleep in overall health and provides an examination of how sleep influences a wide range of neurological disorders. From neurodevelopmental issues to neurodegenerative diseases, this book offers a detailed review of how sleep science can be applied to improve patient outcomes in various neurological conditions. Structured around key neurological topics, the book offers insights into conditions such as epilepsy, stroke, and traumatic brain injury, emphasizing the importance of sleep management in their treatment. Each chapter not only discusses the scientific underpinnings of sleep but also provides tangible strategies for integrating sleep health into primary neurological care.
  • Artificial Intelligence and Clinical Cognition in Pediatric and Neonatal Medicine

    • 1st Edition
    • Anthony Chang + 1 more
    • English
    Artificial Intelligence and Clinical Cognition in Pediatric and Neonatal Medicine is an essential guide with an introduction to data science and artificial intelligence to provide the reader with a quick orientation and education on AI in healthcare. This book vastly improves the speed of adoption of AI in pediatric and neonatal healthcare by providing a framework of AI deployment in children and healthcare. In addition to a large section on the principles and theories of artificial intelligence as well as its application in a number of pediatric subspecialties, the book will have about 50 commentaries that all have the same structure The book is presented in a systematic manner for all clinicians to understand the in-depth thinking of the leaders in the pediatric AI domain from an international perspective. Artificial Intelligence and Clinical Cognition in Pediatric and Neonatal Medicine is an essential guide with an introduction to data science and artificial intelligence to provide the reader with a quick orientation and education on AI in healthcare. It also offers a framework for success in planning, deployment, implementation, and evaluation of AI models in healthcare. In addition, current state of the art of pediatric subspecialties will be presented with future directions to guide the pediatric and neonatal clinicians. Finally, a colorful collection of commentaries by leaders of AI use in children’s health is inserted throughout the book.
  • Antimicrobial Resistance, Sepsis, and the Invisible Threats to Women’s Health

    • 1st Edition
    • Uzma Syed + 1 more
    • English
    Antimicrobial Resistance, Sepsis, and the Invisible Threats to Women’s Health serves as a comprehensive guide to understanding and addressing the health disparities and risk factors that impact women globally. By focusing on the burden of antimicrobial resistance (AMR) and sepsis on women's health, the book aims to educate both the researchers and healthcare professionals. The book begins by introducing the fundamental concepts of antimicrobial resistance and sepsis, setting the stage for a deeper exploration of their impact on women's health. It examines the epidemiology of sepsis and antimicrobial resistance in women, highlighting key risk factors and research gaps and discusses reproductive health, antimicrobial resistance, and sepsis in detail, emphasizing the disproportionate impact on women's health. Additional coverage includes strategies for recruiting women in clinical trials and research studies, exploring the One Health approach integrating women's health into the broader context of AMR and sepsis, and the role of artificial intelligence and technology in combating AMR and sepsis. The book concludes with case studies of female patients and their families affected by AMR and sepsis. Through insightful analysis and practical recommendations, the book aims to provide a deeper understanding of the challenges faced by women seeking healthcare and how to improve their outcomes when affected by sepsis due to antimicrobial resistance through informed practices.
  • Emerging Technologies in Bioengineering for Oncology

    Fundamentals, Research, and Future Prospects
    • 1st Edition
    • Saikat Das + 2 more
    • English
    Emerging Bioengineering Technologies for Oncology explores the integration of engineering, biology, and medicine to tackle challenges in developing innovative tools for cancer diagnosis and treatment. This comprehensive resource addresses the evolving landscape of bioengineering in oncology, highlighting the intersection of various disciplines to drive advancements in diagnostic and therapeutic approaches. The book explores a range of cutting-edge technologies such as lab-on-chip devices, wearable biosensors, 3D bioprinting, and targeted nanomedicine, offering promising avenues for enhanced diagnostic precision, treatment effectiveness, and personalized healthcare. Geared towards medical students and professionals, it provides detailed insights into the latest developments, practical applications, and future research directions in the field. By offering a deep dive into the realm of bioengineering for oncology, this book serves as a valuable asset for those seeking to advance cancer care through interdisciplinary collaboration and innovation.