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Smart Approaches for Cancer Diagnosis, Therapy, and its Associated Challenges

  • 1st Edition - January 1, 2027
  • Latest edition
  • Editors: Paul A. Millner, Arindam Pramanik, Ajay Kumar
  • Language: English

Smart and Translational Approaches in Cancer Diagnosis and Therapy: Innovations and Challenges presents a comprehensive exploration of cutting-edge technologies transforming cancer… Read more

Description

Smart and Translational Approaches in Cancer Diagnosis and Therapy: Innovations and Challenges presents a comprehensive exploration of cutting-edge technologies transforming cancer care. This edited volume bridges foundational science with clinical relevance, offering insights into theranostics, nanomedicine, and molecular therapeutics. The book delves into advanced diagnostic tools such as biosensors and theranostic nanoparticles, and therapeutic innovations including peptide-drug conjugates, epigenetic modulation, and nucleic acid-based treatments. It addresses key challenges in glioblastoma, pediatric brain tumors, and drug-resistant cancers, while highlighting translational strategies that integrate diagnostics and therapy. Academics benefit from a multidisciplinary reference that supports research, fosters innovation, and enhances understanding of emerging cancer therapies. It equips researchers with the latest developments to advance precision medicine and improve patient outcomes.

Key features

  • Explores cutting-edge cancer therapies including nanotechnology, epigenetics, and nucleic acid-based treatments
  • Provides interdisciplinary insights from oncology, molecular biology, and bioengineering to address complex cancer challenges
  • Highlights translational innovations in diagnostics and personalized medicine for improved clinical outcomes

Readership

Cancer researchers and translational scientists specializing in oncology, nanomedicine, and molecular therapeutics

Table of contents

1. Cancer Theranostic: A Conceptual Framework and Overview of Current Approaches

2. Advances in Sensors and Biosensors for Cancer Detection

3. Nanoparticle-Based Cancer Diagnosis: Innovations in Imaging and Biomarker Detection

4. Metallic Nanoparticles for Theranostic Applications

5. Cancer Metabolomics: Biomarker Discovery and Clinical Translation

6. Nanotechnology in Targeted Drug Delivery for Cancer Therapy

7. Innovative Strategies in Therapeutic Management of Glioblastoma

8. Stromal Regulation of Therapy Responses in Breast Cancers

9. Advances of Peptide-Drug Conjugates for Management of Metastatic Cancers

10. Epigenetic Approaches in Cancer Therapy

11. Nucleic Acid-Based Approaches for Cancer Therapeutics

12. Harnessing the Power of Extracellular Vehicles in Cancer Therapy

13. Advancements in Immunotherapy, Vaccines and CAR-T Therapy

14. Challenges for Drug Discovery in Paediatric Brain Tumors

15. Overcoming Challenges in Drug Resistant Cancer Therapeutics

16. Bridging the Translational Divide: Current Gaps and Future Directions in Cancer Theranostics

Product details

  • Edition: 1
  • Latest edition
  • Published: January 1, 2027
  • Language: English

About the editors

PM

Paul A. Millner

Professor Paul A. Millner is a leading figure in bionanotechnology at the University of Leeds, currently serving as a Visiting Professor in the School of Biomedical Sciences. He earned his BSc in Biochemistry and PhD in Plant Sciences from Leeds, followed by postdoctoral research at Purdue University and Imperial College London. Initially focused on plant cell signaling, his research transitioned to biotechnology, emphasizing biosensors, biocatalysis and cancer theranostics.

Professor Millner's work centers on integrating biomolecules like enzymes and synthetic receptors (e.g., Affimers) with non-biological surfaces to develop functional devices for diagnostics and environmental applications. His group has pioneered reagentless electrochemical immunosensors and explored nanoparticle-based systems for targeted drug delivery and imaging. Notably, he coordinated EU-funded projects such as ELISHA and SANTS, leading to the establishment of ELISHA Systems Ltd. He has published more than 150 research articles and numerous books and book chapters.

Affiliations and expertise
University of Leeds, UK

AP

Arindam Pramanik

Dr. Arindam Pramanik is an Assistant Professor at the Amity University Noida, and serves as a Visiting Research Fellow at the University of Leeds. He earned his PhD in Life Science and Biotechnology from Jadavpur University, focusing on targeted drug delivery using polymeric and metal-based nanoparticles. His postdoctoral research includes prestigious fellowships from India's Department of Science and Technology (DST) and Department of Biotechnology (DBT). As a part of Newton fellowship from royal society at University of Leeds, he contributed to cancer therapeutics, notably developing Affimer-conjugated cubosomes for targeted delivery to colon and breast cancer cells. He has been recognized internationally, earning him the Joe Gray Travel Award by Oregon State University, USA. Dr. Pramanik's research interests encompass cancer biomarkers, gene therapy, and nanostructured drug delivery systems, including liposomal and hydrogel-based platforms. He is leading multiple research projects and has published numerous book/chapters in reputed journals.

Affiliations and expertise
University of Leeds, UK

AK

Ajay Kumar

Dr. Ajay Kumar is currently working as an assistant professor at Amity Institute of Biotechnology, Amity University, Noida, India. Dr. Kumar recently completed his tenure as a visiting scientist from Agriculture Research Organization, Volcani Center, Israel. He has published more than 200 research, review articles, and book chapters in international and national journals. He serves as an associate editor for Frontiers in Microbiology, BMC Microbiology and as guest editor for various journals such as Plants, Microorganisms, and Sustainability. Dr. Kumar has also edited more than 40 books with the leading publishers such as Elsevier, Springer, and Wiley. Dr. Kumar’s research experience is in the field of plant–microbe interactions, postharvest management, cyanobacterial biology, and so on

Affiliations and expertise
Amity Institute of Biotechnology, Amity University, Noida, India